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Fusion gene ID: 25248 |
FusionGeneSummary for NUP88_NLRP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NUP88_NLRP1 | Fusion gene ID: 25248 | Hgene | Tgene | Gene symbol | NUP88 | NLRP1 | Gene ID | 4927 | 22861 |
| Gene name | nucleoporin 88 | NLR family pyrin domain containing 1 | |
| Synonyms | - | AIADK|CARD7|CIDED|CLR17.1|DEFCAP|DEFCAP-L/S|MSPC|NAC|NALP1|PP1044|SLEV1|VAMAS1 | |
| Cytomap | 17p13.2 | 17p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nuclear pore complex protein Nup88karyoporinnuclear pore complex protein 88nucleoporin 88kDanucleoporin Nup88 | NACHT, LRR and PYD domains-containing protein 1NACHT, LRR and PYD containing protein 1NACHT, leucine rich repeat and PYD (pyrin domain) containing 1NACHT, leucine rich repeat and PYD containing 1caspase recruitment domain protein 7caspase recruitment | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q99567 | Q9C000 | |
| Ensembl transtripts involved in fusion gene | ENST00000573169, ENST00000573584, | ENST00000262467, ENST00000345221, ENST00000269280, ENST00000572272, ENST00000354411, ENST00000577119, ENST00000571307, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 7 X 4 X 6=168 |
| # samples | 1 | 9 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(9/168*10)=-0.900464326449086 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NUP88 [Title/Abstract] AND NLRP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NLRP1 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 15212762 |
| Tgene | NLRP1 | GO:0051402 | neuron apoptotic process | 15212762 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-KQ-A41N-01A | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000573169 | ENST00000262467 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-3CDS | ENST00000573169 | ENST00000345221 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-3CDS | ENST00000573169 | ENST00000269280 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-3CDS | ENST00000573169 | ENST00000572272 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-intron | ENST00000573169 | ENST00000354411 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-intron | ENST00000573169 | ENST00000577119 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| intron-5UTR | ENST00000573169 | ENST00000571307 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| In-frame | ENST00000573584 | ENST00000262467 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| In-frame | ENST00000573584 | ENST00000345221 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| In-frame | ENST00000573584 | ENST00000269280 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| In-frame | ENST00000573584 | ENST00000572272 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| 5CDS-intron | ENST00000573584 | ENST00000354411 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| 5CDS-intron | ENST00000573584 | ENST00000577119 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
| 5CDS-5UTR | ENST00000573584 | ENST00000571307 | NUP88 | chr17 | 5319833 | - | NLRP1 | chr17 | 5440260 | - |
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FusionProtFeatures for NUP88_NLRP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NUP88 | NLRP1 |
| Essential component of nuclear pore complex. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NUP88_NLRP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000262467_chr17_5440260_-_575aa MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGG EEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCRLDQTTLSDEMRQELRALEQEKPQL LIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAGKSHEESSPEVVPVELLCVPSPASQGD LHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAE PGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVT FHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVK >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000345221_chr17_5440260_-_629aa MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGG EEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCRLDQTTLSDEMRQELRALEQEKPQL LIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTK PLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAV EAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLY LIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQY >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000269280_chr17_5440260_-_629aa MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGG EEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCRLDQTTLSDEMRQELRALEQEKPQL LIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTK PLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAV EAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLY LIPSDCSIRKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQY >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000572272_chr17_5440260_-_673aa MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGG EEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCRLDQTTLSDEMRQELRALEQEKPQL LIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTK PLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAV EAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLY LIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKD ETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000262467_chr17_5440260_-_1725nt ATGGCGGCCGCCGAGGGACCGGTGGGCGACGGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGA CTGAAAAACCAGAGTCCAACCGAAGCTGAGAAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTG GTCTTTGGCCTCGGCGGAGAGCTTTTCCTGTGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGC GAAGAGCCCGCCCTGTCCCAGTACCAGAGATTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAA CATCATGTAGCACTTATAGGAATAAAAGGACTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAA TCAACAGTGAATTGTAGGCTGGACCAGACAACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTG CTCATCTTCAGCAGACGGAAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAG CGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCT GAGATTGCAGGCAAGAGCCACGAGGAAAGCTCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGAC CTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTG TACCGAGTTCACTTCCCTGTAGCTGGCTCCTACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATT GAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAG CCTGGAGCTGTGGAAGCTGTGCACCTCCCTCACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTT AAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTC CTCCTGAAAATGATCCATAATGCCCTGCGCTTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACC TTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAGGCCATAGATGATCTAGAAATGAAATTCCAGTTTGTGCGAATCCACAAG CCACCCCCGCTGACCCCACTTTATATGGGCTGTCGTTACACTGTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTG GAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAA GACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAAGGAACACCAGCCAGCCGTGGAACCTCAGGTGCAACAGAGAC >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000345221_chr17_5440260_-_1887nt ATGGCGGCCGCCGAGGGACCGGTGGGCGACGGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGA CTGAAAAACCAGAGTCCAACCGAAGCTGAGAAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTG GTCTTTGGCCTCGGCGGAGAGCTTTTCCTGTGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGC GAAGAGCCCGCCCTGTCCCAGTACCAGAGATTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAA CATCATGTAGCACTTATAGGAATAAAAGGACTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAA TCAACAGTGAATTGTAGGCTGGACCAGACAACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTG CTCATCTTCAGCAGACGGAAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAG CGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCT GAGATTGCAGAGGAAAGCTCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAG CCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCAC TTCCCTGTAGCTGGCTCCTACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTG TGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTG GAAGCTGTGCACCTCCCTCACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGG ATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATG ATCCATAATGCCCTGCGCTTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTAC CTGATCCCAAGTGACTGCTCCATTCGGAAGGAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTT GGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGATCTC ATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATAGCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTAT CGAGAGCAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAGAGG GTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGGAAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTAC >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000269280_chr17_5440260_-_1887nt ATGGCGGCCGCCGAGGGACCGGTGGGCGACGGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGA CTGAAAAACCAGAGTCCAACCGAAGCTGAGAAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTG GTCTTTGGCCTCGGCGGAGAGCTTTTCCTGTGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGC GAAGAGCCCGCCCTGTCCCAGTACCAGAGATTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAA CATCATGTAGCACTTATAGGAATAAAAGGACTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAA TCAACAGTGAATTGTAGGCTGGACCAGACAACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTG CTCATCTTCAGCAGACGGAAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAG CGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCT GAGATTGCAGAGGAAAGCTCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAG CCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCAC TTCCCTGTAGCTGGCTCCTACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTG TGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTG GAAGCTGTGCACCTCCCTCACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGG ATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATG ATCCATAATGCCCTGCGCTTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTAC CTGATCCCAAGTGACTGCTCCATTCGGAAGGAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTT GGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGATCTC ATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATAGCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTAT CGAGAGCAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAGAGG GTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGGAAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTAC >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000572272_chr17_5440260_-_2019nt ATGGCGGCCGCCGAGGGACCGGTGGGCGACGGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGA CTGAAAAACCAGAGTCCAACCGAAGCTGAGAAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTG GTCTTTGGCCTCGGCGGAGAGCTTTTCCTGTGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGC GAAGAGCCCGCCCTGTCCCAGTACCAGAGATTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAA CATCATGTAGCACTTATAGGAATAAAAGGACTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAA TCAACAGTGAATTGTAGGCTGGACCAGACAACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTG CTCATCTTCAGCAGACGGAAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAG CGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCT GAGATTGCAGAGGAAAGCTCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAG CCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCAC TTCCCTGTAGCTGGCTCCTACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTG TGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTG GAAGCTGTGCACCTCCCTCACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGG ATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATG ATCCATAATGCCCTGCGCTTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTAC CTGATCCCAAGTGACTGCTCCATTCGGAAGGCCATAGATGATCTAGAAATGAAATTCCAGTTTGTGCGAATCCACAAGCCACCCCCGCTG ACCCCACTTTATATGGGCTGTCGTTACACTGTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTGGAGCTCTGCTAT CGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGAT GAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATAGCCGTACCTTCA CCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAGCAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGAC AAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGGAAGCTGTTCAGC TTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCCCTGAAGGAGACCCATCCTCACCTCATTATGGAACTCTGGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000262467_chr17_5440260_-_2664nt ACAGACCCCTGGGAGGTGTACTTTCCGGGTGCAGACCGCGAATGGATCGCAGCGTATTCTGGGAAGTGTTGTTTTATCGACCGGCCCCAC GTGGAGACAGATTTAGGCATCCAAGCGAAATGCGTGAGGCCAGCCCGACCTGCACTGAGGGAGGTAAGTCTTGAGGGAAAGTTCTGGATG CCTGGGTTTACCCAGATGGAGGTGTCCAATAGGCAATTAGATACACAAGTCTCAGGCTCTCCCCAGGTGCTAGATTTCCAGCAGCACCAC CATTATGTTGACTTCTCGTCCCGCCCCCTTGGGCTTCAGAAATAATGGTGATTGGCTTTCCCTTGGTGACGCCCCTGCTTGGTGGGCTGG CCTCGCCTTCGCCCCCCGACCTGGCACGAGCCTCTCGAGCTTCCGGGCCGTCTGCTCGGTGATTGGCCGAAACAGTGAGTGGACGGCCGC GGATTGGCTGTGCTCAGCGGCGGGCTGAGCAACTGGAGTGAGGGGAGCAGTTGGGCCAAGATGGCGGCCGCCGAGGGACCGGTGGGCGAC GGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGACTGAAAAACCAGAGTCCAACCGAAGCTGAG AAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTGGTCTTTGGCCTCGGCGGAGAGCTTTTCCTG TGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGCGAAGAGCCCGCCCTGTCCCAGTACCAGAGA TTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAACATCATGTAGCACTTATAGGAATAAAAGGA CTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAATCAACAGTGAATTGTAGGCTGGACCAGACA ACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGGAAACCAAGTGTG ATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCT TCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGGCAAGAGCCACGAGGAAAGC TCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAGCCTTTGGGGACTGACGAT GACTTCTGGGGCCCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCC TACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTGTGGGACCAGTTCCTGGGT GAGATCAACCCACAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCT CACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGGATGCTCCTGGAGAAGCCA GCCAGGGTGGAGCTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGC TTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTACCTGATCCCAAGTGACTGC TCCATTCGGAAGGCCATAGATGATCTAGAAATGAAATTCCAGTTTGTGCGAATCCACAAGCCACCCCCGCTGACCCCACTTTATATGGGC TGTCGTTACACTGTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGAC CAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAG GCCTTGGTGAAACCAGGAAGGAACACCAGCCAGCCGTGGAACCTCAGGTGCAACAGAGACGCCAGGAGATACTAGTGCCCAGCAGCCTGC GGCAGTACCAATGAAGCCAGAGAGGGCTTGGTGGATGACAAGGAGGCCTGAGTAGACCGCAGGTGGGTCTGAGAAATGGGCTTAGGTGAG GCAGGTCTTTGAAGGATTTGTTCTTAATCATATGCGAGATGCTCAAAAGGCTGGATGCCTGCTTTTGTGGGTGAAGAGCAAGAAGAGAAA ACAGGTTGTACACATACAGATGCAGATGGAGAGACAGAGAAAAAAAAGGAAGAAGGCAGAGAAATGCACCAATTCTTGAGCTGTATTATC TCTGGACCTTGGGATTGTGGGAGGCTTTATTTTACTACTGATTTTGCCTACACTGTTTTCTCAATTTCTAGTTTTCTACAAAGATGATGT >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000345221_chr17_5440260_-_3032nt ACAGACCCCTGGGAGGTGTACTTTCCGGGTGCAGACCGCGAATGGATCGCAGCGTATTCTGGGAAGTGTTGTTTTATCGACCGGCCCCAC GTGGAGACAGATTTAGGCATCCAAGCGAAATGCGTGAGGCCAGCCCGACCTGCACTGAGGGAGGTAAGTCTTGAGGGAAAGTTCTGGATG CCTGGGTTTACCCAGATGGAGGTGTCCAATAGGCAATTAGATACACAAGTCTCAGGCTCTCCCCAGGTGCTAGATTTCCAGCAGCACCAC CATTATGTTGACTTCTCGTCCCGCCCCCTTGGGCTTCAGAAATAATGGTGATTGGCTTTCCCTTGGTGACGCCCCTGCTTGGTGGGCTGG CCTCGCCTTCGCCCCCCGACCTGGCACGAGCCTCTCGAGCTTCCGGGCCGTCTGCTCGGTGATTGGCCGAAACAGTGAGTGGACGGCCGC GGATTGGCTGTGCTCAGCGGCGGGCTGAGCAACTGGAGTGAGGGGAGCAGTTGGGCCAAGATGGCGGCCGCCGAGGGACCGGTGGGCGAC GGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGACTGAAAAACCAGAGTCCAACCGAAGCTGAG AAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTGGTCTTTGGCCTCGGCGGAGAGCTTTTCCTG TGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGCGAAGAGCCCGCCCTGTCCCAGTACCAGAGA TTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAACATCATGTAGCACTTATAGGAATAAAAGGA CTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAATCAACAGTGAATTGTAGGCTGGACCAGACA ACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGGAAACCAAGTGTG ATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCT TCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGCTCCCCAGAGGTA GTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGC CCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCCTACCGCTGGCCC AACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCA CAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCTCACTTTGTGGCT CTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAG CTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGCTTCATTCCCGTC ACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAG GAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAA GTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCC CGCATAGCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAGCAGCTGATAGCCCGAGTGACATCG GTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAG ATGCGGAAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCCCTGAAGGAGACCCATCCTCACCTC ATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGACTCCTGCCACTCAGCAGCTGAAGTATCAACACCAGCCCTTGACCCTTGAGTCCT GGCTTTGGCTGACCCTTCTTTGGGTCTCAGTTTCTTTCTCTGCAAACAAGTTGCCATCTGGTTTGCCTTCCAGCACTAAAGTAATGGAAC TTTGATGATGCCTTTGCTGGGCATTATGTGTCCATGCCAGGGATGCCACAGGGGGCCCCAGTCCAGGTGGCCTAACAGCATCTCAGGGAA TGTCCATCTGGAGCTGGCAAGACCCCTGCAGACCTCATAGAGCCTCATCTGGTGGCCACAGCAGCCAAGCCTAGAGCCCTCCGGATCCCA TCCAGGCGCAAAGAGGAATAGGAGGGACATGGAACCATTTGCCTCTGGCTGTGTCACAGGGTGAGCCCCAAAATTGGGGTTCAGCGTGGG AGGCCACGTGGATTCTTGGCTTTGTACAGGAAGATCTACAAGAGCAAGCCAACAGAGTAAAGTGGAAGGAAGTTTATTCAGAAAATAAAG GAGTATCACAGCTCTTTTAGAATTTGTCTAGCAGGCTTTCCAGTTTTTACCAGAAAACCCCTATAAATTAAAAATTTTTTACTTAAATTT >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000269280_chr17_5440260_-_3024nt ACAGACCCCTGGGAGGTGTACTTTCCGGGTGCAGACCGCGAATGGATCGCAGCGTATTCTGGGAAGTGTTGTTTTATCGACCGGCCCCAC GTGGAGACAGATTTAGGCATCCAAGCGAAATGCGTGAGGCCAGCCCGACCTGCACTGAGGGAGGTAAGTCTTGAGGGAAAGTTCTGGATG CCTGGGTTTACCCAGATGGAGGTGTCCAATAGGCAATTAGATACACAAGTCTCAGGCTCTCCCCAGGTGCTAGATTTCCAGCAGCACCAC CATTATGTTGACTTCTCGTCCCGCCCCCTTGGGCTTCAGAAATAATGGTGATTGGCTTTCCCTTGGTGACGCCCCTGCTTGGTGGGCTGG CCTCGCCTTCGCCCCCCGACCTGGCACGAGCCTCTCGAGCTTCCGGGCCGTCTGCTCGGTGATTGGCCGAAACAGTGAGTGGACGGCCGC GGATTGGCTGTGCTCAGCGGCGGGCTGAGCAACTGGAGTGAGGGGAGCAGTTGGGCCAAGATGGCGGCCGCCGAGGGACCGGTGGGCGAC GGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGACTGAAAAACCAGAGTCCAACCGAAGCTGAG AAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTGGTCTTTGGCCTCGGCGGAGAGCTTTTCCTG TGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGCGAAGAGCCCGCCCTGTCCCAGTACCAGAGA TTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAACATCATGTAGCACTTATAGGAATAAAAGGA CTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAATCAACAGTGAATTGTAGGCTGGACCAGACA ACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGGAAACCAAGTGTG ATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCT TCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGCTCCCCAGAGGTA GTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGC CCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCCTACCGCTGGCCC AACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCA CAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCTCACTTTGTGGCT CTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAG CTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGCTTCATTCCCGTC ACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAG GAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAA GTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAACCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCC CGCATAGCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAGCAGCTGATAGCCCGAGTGACATCG GTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAGCAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAG ATGCGGAAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCCCTGAAGGAGACCCATCCTCACCTC ATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGACTCCTGCCACTCAGCAGCTGAAGTATCAACACCAGCCCTTGACCCTTGAGTCCT GGCTTTGGCTGACCCTTCTTTGGGTCTCAGTTTCTTTCTCTGCAAACAAGTTGCCATCTGGTTTGCCTTCCAGCACTAAAGTAATGGAAC TTTGATGATGCCTTTGCTGGGCATTATGTGTCCATGCCAGGGATGCCACAGGGGGCCCCAGTCCAGGTGGCCTAACAGCATCTCAGGGAA TGTCCATCTGGAGCTGGCAAGACCCCTGCAGACCTCATAGAGCCTCATCTGGTGGCCACAGCAGCCAAGCCTAGAGCCCTCCGGATCCCA TCCAGGCGCAAAGAGGAATAGGAGGGACATGGAACCATTTGCCTCTGGCTGTGTCACAGGGTGAGCCCCAAAATTGGGGTTCAGCGTGGG AGGCCACGTGGATTCTTGGCTTTGTACAGGAAGATCTACAAGAGCAAGCCAACAGAGTAAAGTGGAAGGAAGTTTATTCAGAAAATAAAG GAGTATCACAGCTCTTTTAGAATTTGTCTAGCAGGCTTTCCAGTTTTTACCAGAAAACCCCTATAAATTAAAAATTTTTTACTTAAATTT >In-frame_NUP88_ENST00000573584_chr17_5319833_-_NLRP1_ENST00000572272_chr17_5440260_-_2529nt ACAGACCCCTGGGAGGTGTACTTTCCGGGTGCAGACCGCGAATGGATCGCAGCGTATTCTGGGAAGTGTTGTTTTATCGACCGGCCCCAC GTGGAGACAGATTTAGGCATCCAAGCGAAATGCGTGAGGCCAGCCCGACCTGCACTGAGGGAGGTAAGTCTTGAGGGAAAGTTCTGGATG CCTGGGTTTACCCAGATGGAGGTGTCCAATAGGCAATTAGATACACAAGTCTCAGGCTCTCCCCAGGTGCTAGATTTCCAGCAGCACCAC CATTATGTTGACTTCTCGTCCCGCCCCCTTGGGCTTCAGAAATAATGGTGATTGGCTTTCCCTTGGTGACGCCCCTGCTTGGTGGGCTGG CCTCGCCTTCGCCCCCCGACCTGGCACGAGCCTCTCGAGCTTCCGGGCCGTCTGCTCGGTGATTGGCCGAAACAGTGAGTGGACGGCCGC GGATTGGCTGTGCTCAGCGGCGGGCTGAGCAACTGGAGTGAGGGGAGCAGTTGGGCCAAGATGGCGGCCGCCGAGGGACCGGTGGGCGAC GGCGAGCTGTGGCAGACCTGGCTTCCTAACCACGTCGTGTTCTTGCGGCTCCGGGAGGGACTGAAAAACCAGAGTCCAACCGAAGCTGAG AAACCAGCTTCTTCGTCGTTGCCTTCGTCGCCGCCGCCGCAGTTGCTGACGAGAAACGTGGTCTTTGGCCTCGGCGGAGAGCTTTTCCTG TGGGACGGAGAAGACAGCTCCTTCTTAGTCGTTCGCCTTCGGGGCCCCAGCGGCGGCGGCGAAGAGCCCGCCCTGTCCCAGTACCAGAGA TTGCTTTGCATAAATCCACCCCTGTTTGAAATCTATCAAGTCTTGTTAAGCCCAACACAACATCATGTAGCACTTATAGGAATAAAAGGA CTTATGGTATTAGAATTACCTAAAAGATGGGGGAAGAATTCTGAATTTGAAGGTGGAAAATCAACAGTGAATTGTAGGCTGGACCAGACA ACTCTGAGTGATGAGATGAGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGGAAACCAAGTGTG ATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACATCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCT TCCCATGTTGCTCAGGCTAATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGCTCCCCAGAGGTA GTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGACCTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGC CCCACGGGGCCTGTGGCTACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCCTACCGCTGGCCC AACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATTGAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCA CAGCACAGCTGGATGGTGGCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCTCACTTTGTGGCT CTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTTAAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAG CTGCATCACATAGTTCTGGAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGCTTCATTCCCGTC ACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACCTTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAG GCCATAGATGATCTAGAAATGAAATTCCAGTTTGTGCGAATCCACAAGCCACCCCCGCTGACCCCACTTTATATGGGCTGTCGTTACACT GTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTGGAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCG GAGTTCTACGTTGGCCACTTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAGGCCTTGGTGAAA CCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATAGCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTT GTGGACCAGTATCGAGAGCAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTGCTGAGCCAGGAG CAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGGAAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAA GATGGACTCTACCAAGCCCTGAAGGAGACCCATCCTCACCTCATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGACTCCTGCCACTC |
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FusionGenePPI for NUP88_NLRP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NUP88 | NUP98, RAE1, NUP214, SET, SIRT7, CUL3, CUL2, CAND1, NXF1, RBM42, CPSF6, CIRBP, ARFGEF2, FLNC, SUZ12, RNF2, G3BP2, DDX19A, NUP62, MCM3, NTRK1, IFI16, NUP85, NUP35, CNTROB, KPNB1, NUP153, NUP107, SEH1L, C11orf30, NUP62CL, TRIM62, COG6, PLEC, PPIP5K2, AAK1, SEC24B, CCDC88A, TRIM25 | NLRP1 | NLRC4, APAF1, CASP9, CASP2, APOA1, CUL3, TRIM68, CLTC, CSNK1E, EIF6, SMC2, WWP2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NUP88_NLRP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NUP88_NLRP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NUP88 | C0019693 | HIV Infections | 1 | CTD_human |
| Tgene | NLRP1 | C1847835 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | 2 | CTD_human;UNIPROT |
| Tgene | NLRP1 | C3808876 | CORNEAL INTRAEPITHELIAL DYSKERATOSIS AND ECTODERMAL DYSPLASIA | 1 | ORPHANET;UNIPROT |
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