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Fusion gene ID: 25233 |
FusionGeneSummary for NUP37_ACSS3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NUP37_ACSS3 | Fusion gene ID: 25233 | Hgene | Tgene | Gene symbol | NUP37 | ACSS3 | Gene ID | 79023 | 79611 |
| Gene name | nucleoporin 37 | acyl-CoA synthetase short chain family member 3 | |
| Synonyms | p37 | - | |
| Cytomap | 12q23.2 | 12q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nucleoporin Nup37nucleoporin 37kDanup107-160 subcomplex subunit Nup37 | acyl-CoA synthetase short-chain family member 3, mitochondrialAMP-binding enzyme, 33217 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8NFH4 | Q9H6R3 | |
| Ensembl transtripts involved in fusion gene | ENST00000552283, ENST00000251074, ENST00000543021, | ENST00000548058, ENST00000261206, ENST00000548324, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 15 X 10 X 7=1050 |
| # samples | 1 | 11 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(11/1050*10)=-3.25481389902883 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NUP37 [Title/Abstract] AND ACSS3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-D3-A2J6-06A | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000552283 | ENST00000548058 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| Frame-shift | ENST00000552283 | ENST00000261206 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| 5CDS-intron | ENST00000552283 | ENST00000548324 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| In-frame | ENST00000251074 | ENST00000548058 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| In-frame | ENST00000251074 | ENST00000261206 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| 5CDS-intron | ENST00000251074 | ENST00000548324 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| 5UTR-3CDS | ENST00000543021 | ENST00000548058 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| 5UTR-3CDS | ENST00000543021 | ENST00000261206 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
| 5UTR-intron | ENST00000543021 | ENST00000548324 | NUP37 | chr12 | 102492884 | - | ACSS3 | chr12 | 81503339 | + |
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FusionProtFeatures for NUP37_ACSS3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NUP37 | ACSS3 |
| Component of the Nup107-160 subcomplex of the nuclearpore complex (NPC). The Nup107-160 subcomplex is required for theassembly of a functional NPC. The Nup107-160 subcomplex is alsorequired for normal kinetochore microtubule attachment, mitoticprogression and chromosome segregation.{ECO:0000269|PubMed:17363900}. | Activates acetate so that it can be used for lipidsynthesis or for energy generation. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NUP37_ACSS3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000548058_chr12_81503339_+_733aa MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGTCTFQEEEADVEGIQYKTLRTFHHGVRVDGIAWSPETRLDSLP PVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRFVEGMLNICYNAVDRHIENGKGDKIAIIYD SPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASF GIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTG GYAVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQD PGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKL KARCLGNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESILSHGTVADC AVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSALSAIVNGKPYKITSTIEDPS >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000261206_chr12_81503339_+_733aa MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGTCTFQEEEADVEGIQYKTLRTFHHGVRVDGIAWSPETRLDSLP PVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRFVEGMLNICYNAVDRHIENGKGDKIAIIYD SPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASF GIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTG GYAVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQD PGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKL KARCLGNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESILSHGTVADC AVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSALSAIVNGKPYKITSTIEDPS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000548058_chr12_81503339_+_2199nt ATGAAGCAAGATGCCTCAAGAAATGCTGCCTACACTGTGGATTGTGAAGATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAATGGG GATTCAGGAAACCTAATTGCATATGGTGGCAATAATTATGTGGTCATTGGCACGTGTACGTTTCAGGAAGAAGAAGCAGACGTTGAAGGC ATTCAGTATAAAACACTTCGAACATTTCACCATGGAGTCAGGGTTGATGGCATAGCTTGGAGCCCAGAGACTAGACTTGATTCATTGCCT CCAGTAATCAAATTTTGTACTTCAGCTGCTGATATGAAAATTAGATTATTTACTTCAGATCTTCAGGATAAAAATGAATATAAGGTTTTA GAGGGCCATACCGATTTCATTAATGGTTTGGTGTTTGATCCCAAAGAAGGCCAAGAAATTGCAAGTGTGAGTGACGATCACACCTGCAGG TTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGAC AGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGC ATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATC CACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTT GGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATT TATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGAC TGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGGTGTGATTAGGCCCACTGGG GGATACGCTGTCATGCTACACTGGTCAATGTCTTCCATATACGGACTTCAACCCGGAGAGGTGTGGTGGGCAGCTTCTGACTTAGGCTGG GTTGTTGGACATTCCTATATCTGCTATGGACCTCTTCTTCATGGGAACACAACAGTTTTATATGAGGGGAAGCCTGTGGGAACACCAGAT GCTGGCGCTTATTTCCGTGTGCTTGCAGAGCATGGAGTAGCTGCCTTGTTTACAGCACCAACTGCAATTAGAGCAATCCGTCAACAGGAC CCTGGGGCAGCTTTGGGGAAGCAGTACTCTCTGACAAGGTTCAAAACATTATTTGTGGCTGGAGAACGATGTGATGTAGAGACCCTGGAA TGGTCCAAAAATGTCTTCAGAGTACCTGTCTTAGACCATTGGTGGCAAACTGAGACTGGATCTCCAATTACTGCGTCATGTGTTGGATTA GGCAATTCTAAAACACCTCCACCAGGGCAAGCAGGAAAAAGCGTCCCAGGATACAATGTTATGATTTTGGATGACAACATGCAAAAACTG AAGGCTCGGTGTTTAGGAAATATTGTGGTAAAGTTACCATTGCCACCTGGGGCTTTTTCAGGACTCTGGAAGAATCAGGAAGCATTCAAG CATTTATACTTTGAAAAATTTCCTGGATATTATGATACCATGGATGCTGGTTACATGGATGAAGAAGGCTATTTGTATGTTATGTCTCGA GTGGATGATGTAATAAATGTTGCAGGTCACAGAATTTCTGCAGGCGCCATTGAAGAGTCAATCCTTTCCCATGGTACCGTGGCAGACTGT GCTGTTGTTGGCAAGGAAGATCCCTTAAAAGGTCATGTCCCCTTAGCACTCTGTGTATTGAGAAAAGATATAAATGCAACAGAGGAGCAA GTTTTGGAAGAAATTGTGAAACACGTTAGACAGAACATTGGCCCTGTGGCTGCTTTTCGAAATGCAGTGTTTGTCAAACAGCTACCCAAA ACCAGATCTGGCAAGATCCCCCGATCAGCTTTATCTGCCATTGTCAATGGCAAGCCATACAAGATAACTTCTACAATTGAAGACCCCAGC >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000261206_chr12_81503339_+_2199nt ATGAAGCAAGATGCCTCAAGAAATGCTGCCTACACTGTGGATTGTGAAGATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAATGGG GATTCAGGAAACCTAATTGCATATGGTGGCAATAATTATGTGGTCATTGGCACGTGTACGTTTCAGGAAGAAGAAGCAGACGTTGAAGGC ATTCAGTATAAAACACTTCGAACATTTCACCATGGAGTCAGGGTTGATGGCATAGCTTGGAGCCCAGAGACTAGACTTGATTCATTGCCT CCAGTAATCAAATTTTGTACTTCAGCTGCTGATATGAAAATTAGATTATTTACTTCAGATCTTCAGGATAAAAATGAATATAAGGTTTTA GAGGGCCATACCGATTTCATTAATGGTTTGGTGTTTGATCCCAAAGAAGGCCAAGAAATTGCAAGTGTGAGTGACGATCACACCTGCAGG TTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGAC AGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGC ATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATC CACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTT GGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATT TATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGAC TGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGGTGTGATTAGGCCCACTGGG GGATACGCTGTCATGCTACACTGGTCAATGTCTTCCATATACGGACTTCAACCCGGAGAGGTGTGGTGGGCAGCTTCTGACTTAGGCTGG GTTGTTGGACATTCCTATATCTGCTATGGACCTCTTCTTCATGGGAACACAACAGTTTTATATGAGGGGAAGCCTGTGGGAACACCAGAT GCTGGCGCTTATTTCCGTGTGCTTGCAGAGCATGGAGTAGCTGCCTTGTTTACAGCACCAACTGCAATTAGAGCAATCCGTCAACAGGAC CCTGGGGCAGCTTTGGGGAAGCAGTACTCTCTGACAAGGTTCAAAACATTATTTGTGGCTGGAGAACGATGTGATGTAGAGACCCTGGAA TGGTCCAAAAATGTCTTCAGAGTACCTGTCTTAGACCATTGGTGGCAAACTGAGACTGGATCTCCAATTACTGCGTCATGTGTTGGATTA GGCAATTCTAAAACACCTCCACCAGGGCAAGCAGGAAAAAGCGTCCCAGGATACAATGTTATGATTTTGGATGACAACATGCAAAAACTG AAGGCTCGGTGTTTAGGAAATATTGTGGTAAAGTTACCATTGCCACCTGGGGCTTTTTCAGGACTCTGGAAGAATCAGGAAGCATTCAAG CATTTATACTTTGAAAAATTTCCTGGATATTATGATACCATGGATGCTGGTTACATGGATGAAGAAGGCTATTTGTATGTTATGTCTCGA GTGGATGATGTAATAAATGTTGCAGGTCACAGAATTTCTGCAGGCGCCATTGAAGAGTCAATCCTTTCCCATGGTACCGTGGCAGACTGT GCTGTTGTTGGCAAGGAAGATCCCTTAAAAGGTCATGTCCCCTTAGCACTCTGTGTATTGAGAAAAGATATAAATGCAACAGAGGAGCAA GTTTTGGAAGAAATTGTGAAACACGTTAGACAGAACATTGGCCCTGTGGCTGCTTTTCGAAATGCAGTGTTTGTCAAACAGCTACCCAAA ACCAGATCTGGCAAGATCCCCCGATCAGCTTTATCTGCCATTGTCAATGGCAAGCCATACAAGATAACTTCTACAATTGAAGACCCCAGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000548058_chr12_81503339_+_4096nt TTTCGTGACCTTGTCCAGTAGAAGGCTATTTAATTTTCACAACTGCTTGAATTTTGACATACAAGATGAAGCAAGATGCCTCAAGAAATG CTGCCTACACTGTGGATTGTGAAGATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAATGGGGATTCAGGAAACCTAATTGCATATG GTGGCAATAATTATGTGGTCATTGGCACGTGTACGTTTCAGGAAGAAGAAGCAGACGTTGAAGGCATTCAGTATAAAACACTTCGAACAT TTCACCATGGAGTCAGGGTTGATGGCATAGCTTGGAGCCCAGAGACTAGACTTGATTCATTGCCTCCAGTAATCAAATTTTGTACTTCAG CTGCTGATATGAAAATTAGATTATTTACTTCAGATCTTCAGGATAAAAATGAATATAAGGTTTTAGAGGGCCATACCGATTTCATTAATG GTTTGGTGTTTGATCCCAAAGAAGGCCAAGAAATTGCAAGTGTGAGTGACGATCACACCTGCAGGTTTGTGGAAGGAATGCTTAACATTT GTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAA CCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTA TCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTG CTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAG AGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGG TTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACC CACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGGTGTGATTAGGCCCACTGGGGGATACGCTGTCATGCTACACTGGT CAATGTCTTCCATATACGGACTTCAACCCGGAGAGGTGTGGTGGGCAGCTTCTGACTTAGGCTGGGTTGTTGGACATTCCTATATCTGCT ATGGACCTCTTCTTCATGGGAACACAACAGTTTTATATGAGGGGAAGCCTGTGGGAACACCAGATGCTGGCGCTTATTTCCGTGTGCTTG CAGAGCATGGAGTAGCTGCCTTGTTTACAGCACCAACTGCAATTAGAGCAATCCGTCAACAGGACCCTGGGGCAGCTTTGGGGAAGCAGT ACTCTCTGACAAGGTTCAAAACATTATTTGTGGCTGGAGAACGATGTGATGTAGAGACCCTGGAATGGTCCAAAAATGTCTTCAGAGTAC CTGTCTTAGACCATTGGTGGCAAACTGAGACTGGATCTCCAATTACTGCGTCATGTGTTGGATTAGGCAATTCTAAAACACCTCCACCAG GGCAAGCAGGAAAAAGCGTCCCAGGATACAATGTTATGATTTTGGATGACAACATGCAAAAACTGAAGGCTCGGTGTTTAGGAAATATTG TGGTAAAGTTACCATTGCCACCTGGGGCTTTTTCAGGACTCTGGAAGAATCAGGAAGCATTCAAGCATTTATACTTTGAAAAATTTCCTG GATATTATGATACCATGGATGCTGGTTACATGGATGAAGAAGGCTATTTGTATGTTATGTCTCGAGTGGATGATGTAATAAATGTTGCAG GTCACAGAATTTCTGCAGGCGCCATTGAAGAGTCAATCCTTTCCCATGGTACCGTGGCAGACTGTGCTGTTGTTGGCAAGGAAGATCCCT TAAAAGGTCATGTCCCCTTAGCACTCTGTGTATTGAGAAAAGATATAAATGCAACAGAGGAGCAAGTTTTGGAAGAAATTGTGAAACACG TTAGACAGAACATTGGCCCTGTGGCTGCTTTTCGAAATGCAGTGTTTGTCAAACAGCTACCCAAAACCAGATCTGGCAAGATCCCCCGAT CAGCTTTATCTGCCATTGTCAATGGCAAGCCATACAAGATAACTTCTACAATTGAAGACCCCAGCATTTTTGGCCACGTAGAAGAAATGC TGAAGCAAGCATAATGAGTTTGTCTTATTCCTATTTTGAGTTGATTTAATTTCTTAATTGAAATTAAATTATTTGAGTTGTTTCTCAGAA ATAAATATTTCAGTAGAAATTACTTGCAAAATGAAATGTGAATTGTAAAACTTGGCCTAAACAAATCTAATGAAAACATGTGAAAGACCT GTGCCTTTTTTTTGGTTTGACCCTGTTAGCATTGTTATTAGTTATCTATAACATGGCTTATTGAATGTCATCTACTGCTTTAGGAAAAAC GTATCTAGTGTATTATTTTTAAAATTGTACCTCCCAAGAAGAACACTTTAATTGAAAGCAACACTAATATAGAGCCACTTCCTGAAACCA AGAATCTGTAGTTTTGATCCAAAATCTAAAACTTAAAGTCAGAAAATAATTAAAATTTTTCTTGTAGAAATTTTAGATATTTTCTAGTAT TCTTTAGATGCTCACATTGTTTTAAATAAAATAGATGAAATGGGAAGTTTAGGTAATCATCTAGACAGATGAAATTATTATCTAGGTAGG AGGGCTTTTCTATACATTTTCTGAGGGAAAGCAGAACACCGGGGTTATAGCTATACCTTCAGGTCTTTTGTTACTTAGGCAAGGAAAACC ACATGTCTGACCTGGTTCAGCATGTAATCCGAGCACTTTGGGAGGCTGAGGCAGGCGGATCACTTGAGGTCAGCAGTTTGAGACGAGCCT GGCCAACATGGTGAAACCCTGTAGCTACTGAAAATACAAAAATAAGCCAGGCGTGGTGGCGGGAGGCTGAGGCAAGGAGAATCACTTGAA TACAAGAGGCAGAGGTTGCAGTGAGCCAAGTTCCCCCACTGTACTCCAGCCTGGGTGACAGAGTAAGACTCCATCTCAAAACAACAAAAA CAACAAAAAAACCACATGCCTGGCGGAGAACAAAGAGATCATTTAGTCCAATCTCTTCATGGAGATGAGGGCTCCTGGGAGCCCCTCTTC ATGTCTCAGGTTCTTAGTTGACTATGTTTATCCAAATGATTCCAGATTCCTGTGGAAACAAGGAATCGATGTACAAATGGGGTAGGGTGG CAAGGAAAACTCTTAAGAGAGAAACATCAAGGTTTTCACATTAGGTTAAAGACAAGAAGGTTTCTAGGCAGGTAGTGTAATGTCTAGGTG ATTTTGAAGTGAACTTAAGCCACTAGGTTTGAGGGACAAAGGACAGTAGAAAATGGTGAAGACTGCAGATCACCTGCTATACCTCAAGGA GCAGCGGACCCAGCAGAATATGGCCCAAAAAGGAGGCAGGTCTCCTGTTGCAAGAGCCTCTGTTTTTTTAAAGAGAAAACAAAGAATCCT GGTTTTTATGTGAAATCTCTAATTTTAAAATAATAACTCATTAAAAATATTGTAATGTCCAAAAGTATCTTTCCATTTAACTTCTAAAAA TCTCTTAAATGTTTTTTTTAAATAATTGTAAAGTGAGTTTTTGTTAAGCTTATAGGAATGGGCCAGTTAACTAAGGTAGACAGATGTAGG AAATTAAATATTTGATTTACTTAGGGATCTATATGACATCAGTTATCAAAGAATACATTTTAACCCAAAAGTATACCATGCTCATTGTAT CTTTGATCGTTCTTCAAGTATTTCTCAATCTTTTAATCTATCAGGAACATTACTATCAAGAGCAGATTGTTGTAACATAATACTCAGGAT ACATGAAATGTATGTGAGAGATAAATAGATAATAGAAAGTTTATTGTTATAAAAATGACCTACAACTTATATAAAAAAATTCTGAAAATG >In-frame_NUP37_ENST00000251074_chr12_102492884_-_ACSS3_ENST00000261206_chr12_81503339_+_2808nt TTTCGTGACCTTGTCCAGTAGAAGGCTATTTAATTTTCACAACTGCTTGAATTTTGACATACAAGATGAAGCAAGATGCCTCAAGAAATG CTGCCTACACTGTGGATTGTGAAGATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAATGGGGATTCAGGAAACCTAATTGCATATG GTGGCAATAATTATGTGGTCATTGGCACGTGTACGTTTCAGGAAGAAGAAGCAGACGTTGAAGGCATTCAGTATAAAACACTTCGAACAT TTCACCATGGAGTCAGGGTTGATGGCATAGCTTGGAGCCCAGAGACTAGACTTGATTCATTGCCTCCAGTAATCAAATTTTGTACTTCAG CTGCTGATATGAAAATTAGATTATTTACTTCAGATCTTCAGGATAAAAATGAATATAAGGTTTTAGAGGGCCATACCGATTTCATTAATG GTTTGGTGTTTGATCCCAAAGAAGGCCAAGAAATTGCAAGTGTGAGTGACGATCACACCTGCAGGTTTGTGGAAGGAATGCTTAACATTT GTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAA CCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTA TCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTG CTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAG AGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGG TTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACC CACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGGTGTGATTAGGCCCACTGGGGGATACGCTGTCATGCTACACTGGT CAATGTCTTCCATATACGGACTTCAACCCGGAGAGGTGTGGTGGGCAGCTTCTGACTTAGGCTGGGTTGTTGGACATTCCTATATCTGCT ATGGACCTCTTCTTCATGGGAACACAACAGTTTTATATGAGGGGAAGCCTGTGGGAACACCAGATGCTGGCGCTTATTTCCGTGTGCTTG CAGAGCATGGAGTAGCTGCCTTGTTTACAGCACCAACTGCAATTAGAGCAATCCGTCAACAGGACCCTGGGGCAGCTTTGGGGAAGCAGT ACTCTCTGACAAGGTTCAAAACATTATTTGTGGCTGGAGAACGATGTGATGTAGAGACCCTGGAATGGTCCAAAAATGTCTTCAGAGTAC CTGTCTTAGACCATTGGTGGCAAACTGAGACTGGATCTCCAATTACTGCGTCATGTGTTGGATTAGGCAATTCTAAAACACCTCCACCAG GGCAAGCAGGAAAAAGCGTCCCAGGATACAATGTTATGATTTTGGATGACAACATGCAAAAACTGAAGGCTCGGTGTTTAGGAAATATTG TGGTAAAGTTACCATTGCCACCTGGGGCTTTTTCAGGACTCTGGAAGAATCAGGAAGCATTCAAGCATTTATACTTTGAAAAATTTCCTG GATATTATGATACCATGGATGCTGGTTACATGGATGAAGAAGGCTATTTGTATGTTATGTCTCGAGTGGATGATGTAATAAATGTTGCAG GTCACAGAATTTCTGCAGGCGCCATTGAAGAGTCAATCCTTTCCCATGGTACCGTGGCAGACTGTGCTGTTGTTGGCAAGGAAGATCCCT TAAAAGGTCATGTCCCCTTAGCACTCTGTGTATTGAGAAAAGATATAAATGCAACAGAGGAGCAAGTTTTGGAAGAAATTGTGAAACACG TTAGACAGAACATTGGCCCTGTGGCTGCTTTTCGAAATGCAGTGTTTGTCAAACAGCTACCCAAAACCAGATCTGGCAAGATCCCCCGAT CAGCTTTATCTGCCATTGTCAATGGCAAGCCATACAAGATAACTTCTACAATTGAAGACCCCAGCATTTTTGGCCACGTAGAAGAAATGC TGAAGCAAGCATAATGAGTTTGTCTTATTCCTATTTTGAGTTGATTTAATTTCTTAATTGAAATTAAATTATTTGAGTTGTTTCTCAGAA ATAAATATTTCAGTAGAAATTACTTGCAAAATGAAATGTGAATTGTAAAACTTGGCCTAAACAAATCTAATGAAAACATGTGAAAGACCT GTGCCTTTTTTTTGGTTTGACCCTGTTAGCATTGTTATTAGTTATCTATAACATGGCTTATTGAATGTCATCTACTGCTTTAGGAAAAAC GTATCTAGTGTATTATTTTTAAAATTGTACCTCCCAAGAAGAACACTTTAATTGAAAGCAACACTAATATAGAGCCACTTCCTGAAACCA AGAATCTGTAGTTTTGATCCAAAATCTAAAACTTAAAGTCAGAAAATAATTAAAATTTTTCTTGTAGAAATTTTAGATATTTTCTAGTAT TCTTTAGATGCTCACATTGTTTTAAATAAAATAGATGAAATGGGAAGTTTAGGTAATCATCTAGACAGATGAAATTATTATCTAGGTAGG |
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FusionGenePPI for NUP37_ACSS3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NUP37 | NUP133, NUP107, NUP85, NUP43, SEC13, UBC, LNX1, NUP160, HYOU1, SEH1L, CCDC183, COMTD1, PNKD, IFI16, KPNB1, NUP153, SNW1 | ACSS3 | LEFTY2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NUP37_ACSS3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NUP37_ACSS3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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