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Fusion gene ID: 25067 |
FusionGeneSummary for NUDCD1_TMEM184C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NUDCD1_TMEM184C | Fusion gene ID: 25067 | Hgene | Tgene | Gene symbol | NUDCD1 | TMEM184C | Gene ID | 84955 | 55751 |
| Gene name | NudC domain containing 1 | transmembrane protein 184C | |
| Synonyms | CML66|OVA66 | TMEM34 | |
| Cytomap | 8q23.1 | 4q31.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nudC domain-containing protein 1chronic myelogenous leukemia tumor antigen 66tumor antigen CML66 | transmembrane protein 184Ctransmembrane protein 34 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q96RS6 | Q9NVA4 | |
| Ensembl transtripts involved in fusion gene | ENST00000239690, ENST00000427660, | ENST00000296582, ENST00000508208, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 3 X 2 X 4=24 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/24*10)=1.05889368905357 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NUDCD1 [Title/Abstract] AND TMEM184C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-E2-A1LH-01A | NUDCD1 | chr8 | 110334538 | - | TMEM184C | chr4 | 148544985 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000239690 | ENST00000296582 | NUDCD1 | chr8 | 110334538 | - | TMEM184C | chr4 | 148544985 | + |
| In-frame | ENST00000239690 | ENST00000508208 | NUDCD1 | chr8 | 110334538 | - | TMEM184C | chr4 | 148544985 | + |
| In-frame | ENST00000427660 | ENST00000296582 | NUDCD1 | chr8 | 110334538 | - | TMEM184C | chr4 | 148544985 | + |
| In-frame | ENST00000427660 | ENST00000508208 | NUDCD1 | chr8 | 110334538 | - | TMEM184C | chr4 | 148544985 | + |
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FusionProtFeatures for NUDCD1_TMEM184C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NUDCD1 | TMEM184C |
| Possible tumor suppressor which may play a role in cellgrowth. {ECO:0000269|PubMed:17072649}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 179_199 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 212_232 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 254_274 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 287_307 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 48_68 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 86_106 | 41 | 439 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 179_199 | 41 | 262 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 212_232 | 41 | 262 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 254_274 | 41 | 262 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 287_307 | 41 | 262 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 48_68 | 41 | 262 | Transmembrane | Helical |
| Tgene | >TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 86_106 | 41 | 262 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NUDCD1 | chr8:110334538 | chr4:148544985 | ENST00000239690 | - | 2 | 10 | 273_361 | 91 | 584 | Domain | CS |
| Hgene | >NUDCD1 | chr8:110334538 | chr4:148544985 | ENST00000427660 | - | 2 | 10 | 273_361 | 62 | 555 | Domain | CS |
| Tgene | TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000296582 | + | 0 | 10 | 17_37 | 41 | 439 | Transmembrane | Helical |
| Tgene | TMEM184C | chr8:110334538 | chr4:148544985 | ENST00000508208 | + | 0 | 8 | 17_37 | 41 | 262 | Transmembrane | Helical |
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FusionGeneSequence for NUDCD1_TMEM184C |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_489aa MEVAANCSLRVKRPLLDPRFEGYKLSLEPLPCYQLELDAAVAEVKLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVM LVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLT NYLTNRYPNLVLILEAKDQQKHFPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMS QLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEAVATGLQDFIICIEMFLAAIAHHY TFSYKPYVQEAEEGSCFDSFLAMWDVSDIRDDISEQVRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAISIASSMPPSPMGHYQG >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_312aa MEVAANCSLRVKRPLLDPRFEGYKLSLEPLPCYQLELDAAVAEVKLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVM LVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLT NYLTNRYPNLVLILEAKDQQKHFPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMS >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_460aa MLYLQGWSMPAVAEVKLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVMLVGIHTKAWFIAGIFLLLTIPISLWVILQ HLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPLCCC PPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFL CVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEEGSCFDSFLAMWDVSDI RDDISEQVRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAISIASSMPPSPMGHYQGFGHTVTPQTTPTTAKISDEILSDTIGEKK >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_283aa MLYLQGWSMPAVAEVKLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVMLVGIHTKAWFIAGIFLLLTIPISLWVILQ HLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPLCCC PPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_1467nt ATGGAGGTGGCGGCTAATTGCTCCCTACGGGTGAAGAGACCTCTGTTGGATCCCCGCTTCGAGGGTTACAAGCTCTCTCTTGAGCCGCTG CCTTGTTACCAGCTGGAGCTTGACGCAGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATGCATGCTTTTGGA ATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAATTTAACAGTAATG CTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTGATATTGCAACAC TTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGATAGTTGGATAGCT TTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATGGGATTCCTTACC AATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTATGTTGCTGTCCA CCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACCACCATCGTTGCT TTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATAAACAACATGTCA CAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGCAAATTTCTTTGT GTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCAAGCAGTAGTTATTGCTTTGTTGGTAAAAGTTGGCGTTATTTCTGAAAAGCATACGTGG GAATGGCAAACTGTAGAAGCTGTGGCCACCGGACTCCAGGATTTTATTATCTGTATTGAGATGTTCCTCGCTGCCATTGCTCATCATTAC ACATTCTCATATAAACCATATGTCCAAGAAGCAGAAGAGGGCTCATGCTTTGATTCCTTTCTTGCCATGTGGGATGTCTCAGATATTAGA GATGATATTTCTGAACAAGTAAGGCATGTTGGACGGACAGTCAGGGGACATCCCAGGAAAAAATTGTTTCCCGAGGATCAAGATCAAAAT GAACATACAAGTTTATTATCATCATCATCACAAGATGCAATTTCCATTGCTTCTTCTATGCCACCTTCACCCATGGGTCACTACCAAGGG TTTGGACACACTGTGACTCCCCAGACTACACCTACCACAGCTAAGATATCTGATGAAATCCTTAGTGATACTATAGGAGAGAAAAAAGAA >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_936nt ATGGAGGTGGCGGCTAATTGCTCCCTACGGGTGAAGAGACCTCTGTTGGATCCCCGCTTCGAGGGTTACAAGCTCTCTCTTGAGCCGCTG CCTTGTTACCAGCTGGAGCTTGACGCAGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATGCATGCTTTTGGA ATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAATTTAACAGTAATG CTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTGATATTGCAACAC TTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGATAGTTGGATAGCT TTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATGGGATTCCTTACC AATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTATGTTGCTGTCCA CCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACCACCATCGTTGCT TTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATAAACAACATGTCA CAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGCAAATTTCTTTGT >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_1380nt ATGCTTTATCTCCAGGGTTGGAGCATGCCTGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATGCATGCTTTT GGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAATTTAACAGTA ATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTGATATTGCAA CACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGATAGTTGGATA GCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATGGGATTCCTT ACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTATGTTGCTGT CCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACCACCATCGTT GCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATAAACAACATG TCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGCAAATTTCTT TGTGTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCAAGCAGTAGTTATTGCTTTGTTGGTAAAAGTTGGCGTTATTTCTGAAAAGCATACG TGGGAATGGCAAACTGTAGAAGCTGTGGCCACCGGACTCCAGGATTTTATTATCTGTATTGAGATGTTCCTCGCTGCCATTGCTCATCAT TACACATTCTCATATAAACCATATGTCCAAGAAGCAGAAGAGGGCTCATGCTTTGATTCCTTTCTTGCCATGTGGGATGTCTCAGATATT AGAGATGATATTTCTGAACAAGTAAGGCATGTTGGACGGACAGTCAGGGGACATCCCAGGAAAAAATTGTTTCCCGAGGATCAAGATCAA AATGAACATACAAGTTTATTATCATCATCATCACAAGATGCAATTTCCATTGCTTCTTCTATGCCACCTTCACCCATGGGTCACTACCAA GGGTTTGGACACACTGTGACTCCCCAGACTACACCTACCACAGCTAAGATATCTGATGAAATCCTTAGTGATACTATAGGAGAGAAAAAA >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_849nt ATGCTTTATCTCCAGGGTTGGAGCATGCCTGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATGCATGCTTTT GGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAATTTAACAGTA ATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTGATATTGCAA CACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGATAGTTGGATA GCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATGGGATTCCTT ACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTATGTTGCTGT CCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACCACCATCGTT GCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATAAACAACATG TCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGCAAATTTCTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_4129nt CGGACTTAGACCCTCAGTAGCTCGGGCACCTAAGCACACAGAAAGCTAGAACACGCATTTCCGGGGCGGGGTCTCGCCACCCTGCCTATA ATGTGAGAATTTAACCAGCGCGGGCCGCCTCCTGGTTGCTAGGGCCTCTGGGTAACAGAGTTCAGACCTTGCCGTCGCGCGCGCGTTAAG TACCAGGAGAACTACATAGCCCAGCATGCAACAGTCTCAACTTTTTCACGGACACTACATTTCCCAGAAGGCAGTTCGCACCGCAGTGTT TTCTGGGATGGGAACCACGCCGCTTCCCAGTCTCTGTGCGAGGCGTGAAGCGCGGACCTTTCAACAAGGGCTTTATTAATTCTCACGCTG CGGCCCTGGAAAGCGATGGAGGTGGCGGCTAATTGCTCCCTACGGGTGAAGAGACCTCTGTTGGATCCCCGCTTCGAGGGTTACAAGCTC TCTCTTGAGCCGCTGCCTTGTTACCAGCTGGAGCTTGACGCAGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACAC ATGCATGCTTTTGGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATG AATTTAACAGTAATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGG GTGATATTGCAACACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTA GATAGTTGGATAGCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTT ATGGGATTCCTTACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCT TTATGTTGCTGTCCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTC ACCACCATCGTTGCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATA ATAAACAACATGTCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTT GGCAAATTTCTTTGTGTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCAAGCAGTAGTTATTGCTTTGTTGGTAAAAGTTGGCGTTATTTCT GAAAAGCATACGTGGGAATGGCAAACTGTAGAAGCTGTGGCCACCGGACTCCAGGATTTTATTATCTGTATTGAGATGTTCCTCGCTGCC ATTGCTCATCATTACACATTCTCATATAAACCATATGTCCAAGAAGCAGAAGAGGGCTCATGCTTTGATTCCTTTCTTGCCATGTGGGAT GTCTCAGATATTAGAGATGATATTTCTGAACAAGTAAGGCATGTTGGACGGACAGTCAGGGGACATCCCAGGAAAAAATTGTTTCCCGAG GATCAAGATCAAAATGAACATACAAGTTTATTATCATCATCATCACAAGATGCAATTTCCATTGCTTCTTCTATGCCACCTTCACCCATG GGTCACTACCAAGGGTTTGGACACACTGTGACTCCCCAGACTACACCTACCACAGCTAAGATATCTGATGAAATCCTTAGTGATACTATA GGAGAGAAAAAAGAACCTTCAGATAAATCCGTGGATTCCTGAACAGTATGGAAAAGCAAACTGTGCAACTACTACATTATATCATTACCT GGTATCCCATGGATTTTGTGCTTGGGACAGACCATAAATGATGGAAAATGTCAACACAAAAATAGCTGAAAGCCAGGTACAACTACTGCA TTTATATATGTAAGTTTTGTATATCAAAAATAATTGGTCTAAATTTCCTAGACTTAGACTTGATTTCTTAACATTAGGGTATCGCATACT CAAATGGTAGACAATGACCCCAACTAAATCTTCCTGATGTTACACTGCTTTATCAAGAGGATGGACTTTTTTTTTTTTGAGACAGACAGA GTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGGTCACTGCAAGCTCTGCCTCCCAAGTTCATGCCATTCTCCTGCCT CAGCCTCCCAAGTAGCTGGGACTACAGGCACCTGCCACCATGCCCAGCTAATTTTTTTTTTTTCAGTAGAGACAGGGTCTCACCATGTTA GCCAGGATGGTCTTGATCTGACCTCGTGATCCGCCGACCTCGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACTGCGCCTGGCCA AGAATGGACATTTTTTAAAAAAACATCAGTACTTCCTACCACTGCTGCATGAGTATAATGCTCCGGAATTATCAGAAAGCATAATGCAGA AATACGAATTAGTGGAACTTAATCATGTGCCATATAAGCTTACCTAACAAACAGTTATATCCCTATTCCTCAACTGAATGTCTTTCAATA AATAAGAATTTATCATTTATTTTCTGCAACTTTTTTATGTCTCATTCTTTAAACATTAAAAACCCTTAATATTTTAACAAAAATTTCTTG ATTAGAGGCACAGTGAAAAAGAAGTCAAAAAAAAAAGTTCTACTTTTCATCAGTGCTATTAAAGGTGGCAGCAAATGTAAATCTTGGCTG AATGGTCTTAATTACTCATTAAACCACAGTCAGAAAGACATATAGGTGCTATTTGGGAAAACTTTTTATTACCTAGGATGGGGTTTCTCT AATTGCTAATCACAACCCCACTGGGTCATGTTTGACATTTTATAATGAAAATAAAACAGAAAGTGCCATAGTATGTTACAGAAAGCAAAG ATGAGTATTGTTTCTCAAAGCCTTTGCTTTATGTATTTATACACATACTCATTCATATCTATCTATATATATAGAGAGAGATAGTGGTTC ACAGTAATCATACAAAGTCTTTATTCCATCCACTATTATAAACATTTCTATTAAAACTAAAACTGGGCTCTATGTAAAAACCCCAAAGAT ACACACACAAAAAAAATCTGTTTGTTAGAACTCAAGTGAATTCAGTAAAGTTGCAGAATACAAAATCAACATACAAAAAGCATTAGCATT TTTATACATAAATAATGAAAATAATGACCTAACTGAAAAATTAAGATGCCATTTATGATAGCATAAAAAAAATACTTACTTAGGAATAAA TTTAACACCAAGGCAGTAAAAGATCTGTATGTACACTGAAAACTATGAAACACTGATGAAAGAAAGACACAAATAAATGGAAAGGTATCC CGTGCTCATGGATCAGAATAATACTGTTAAAATGGTCACACTACCCAAAGCAATTCAGAATCAATGCAATCCTATCAAAATTCCAATGGC ATTATTTACACAAACAGAAAAAAATCCTAAAATTCATATGTAACGATAAAAGACCCTGAATAGGCAAAAGAATACTGAGGAAAAAATGTT GGAGACATCACATTTCCTAATTATAAATTATACTACAAAACTATAGTAATCAAGACAGTATGGTACTGGTATAAAAACACATACACAGGC CAGTGGGACAGAAGAAAGAGTCCAGATATAAATCCAAACATACACAGTCAACTAATTTTTGACAAAGACACCAAGAAGACACATCGGGGA AAGAACAGTCTTCATTAAGTGTTCTTAATGAAGATGCTGGGAAAACTGCACTTCCACATGCAAAACAATGAAATCAGACCCTTATCTTAG ACCTACACAACAATCAATTCAAAATGGATAAAAGACCTAAATGTAAGACCAGAAACTATAGAAGAGAACATAGGAGAAAAGTTCCTGGAC ACTGACCCTTGGCAATGATTTTTTGGATATCACACCAAAAGCTCAGTCAACAAAAACAAAAACAAATGTGACTACATCAAACCAAAAAGC >In-frame_NUDCD1_ENST00000239690_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_1482nt CGGACTTAGACCCTCAGTAGCTCGGGCACCTAAGCACACAGAAAGCTAGAACACGCATTTCCGGGGCGGGGTCTCGCCACCCTGCCTATA ATGTGAGAATTTAACCAGCGCGGGCCGCCTCCTGGTTGCTAGGGCCTCTGGGTAACAGAGTTCAGACCTTGCCGTCGCGCGCGCGTTAAG TACCAGGAGAACTACATAGCCCAGCATGCAACAGTCTCAACTTTTTCACGGACACTACATTTCCCAGAAGGCAGTTCGCACCGCAGTGTT TTCTGGGATGGGAACCACGCCGCTTCCCAGTCTCTGTGCGAGGCGTGAAGCGCGGACCTTTCAACAAGGGCTTTATTAATTCTCACGCTG CGGCCCTGGAAAGCGATGGAGGTGGCGGCTAATTGCTCCCTACGGGTGAAGAGACCTCTGTTGGATCCCCGCTTCGAGGGTTACAAGCTC TCTCTTGAGCCGCTGCCTTGTTACCAGCTGGAGCTTGACGCAGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACAC ATGCATGCTTTTGGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATG AATTTAACAGTAATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGG GTGATATTGCAACACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTA GATAGTTGGATAGCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTT ATGGGATTCCTTACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCT TTATGTTGCTGTCCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTC ACCACCATCGTTGCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATA ATAAACAACATGTCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTT GGCAAATTTCTTTGTGTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCCTTAACCCCGAAACTGACTATACTGGAGAAGGAAAGGCCGTGTA AAGACACAACAAGAAAGCAGAATCTGCAATCCAGGAAGAGAATCCTCACAAGAAACCAAACTTGCCAACACCTTGATCATGGTCTTCCAG >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000296582_chr4_148544985_+_3766nt AGTACTTCATAGACTTTATCATACTTCGTAGCATCCAGTATGTTTTCTTTGCTAAGATTATTGATTTTGTATTGAAGGGTCCCATGTCCA TCGTTTTCAATGCTTTATCTCCAGGGTTGGAGCATGCCTGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATG CATGCTTTTGGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAAT TTAACAGTAATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTG ATATTGCAACACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGAT AGTTGGATAGCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATG GGATTCCTTACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTA TGTTGCTGTCCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACC ACCATCGTTGCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATA AACAACATGTCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGC AAATTTCTTTGTGTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCAAGCAGTAGTTATTGCTTTGTTGGTAAAAGTTGGCGTTATTTCTGAA AAGCATACGTGGGAATGGCAAACTGTAGAAGCTGTGGCCACCGGACTCCAGGATTTTATTATCTGTATTGAGATGTTCCTCGCTGCCATT GCTCATCATTACACATTCTCATATAAACCATATGTCCAAGAAGCAGAAGAGGGCTCATGCTTTGATTCCTTTCTTGCCATGTGGGATGTC TCAGATATTAGAGATGATATTTCTGAACAAGTAAGGCATGTTGGACGGACAGTCAGGGGACATCCCAGGAAAAAATTGTTTCCCGAGGAT CAAGATCAAAATGAACATACAAGTTTATTATCATCATCATCACAAGATGCAATTTCCATTGCTTCTTCTATGCCACCTTCACCCATGGGT CACTACCAAGGGTTTGGACACACTGTGACTCCCCAGACTACACCTACCACAGCTAAGATATCTGATGAAATCCTTAGTGATACTATAGGA GAGAAAAAAGAACCTTCAGATAAATCCGTGGATTCCTGAACAGTATGGAAAAGCAAACTGTGCAACTACTACATTATATCATTACCTGGT ATCCCATGGATTTTGTGCTTGGGACAGACCATAAATGATGGAAAATGTCAACACAAAAATAGCTGAAAGCCAGGTACAACTACTGCATTT ATATATGTAAGTTTTGTATATCAAAAATAATTGGTCTAAATTTCCTAGACTTAGACTTGATTTCTTAACATTAGGGTATCGCATACTCAA ATGGTAGACAATGACCCCAACTAAATCTTCCTGATGTTACACTGCTTTATCAAGAGGATGGACTTTTTTTTTTTTGAGACAGACAGAGTC TTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGGTCACTGCAAGCTCTGCCTCCCAAGTTCATGCCATTCTCCTGCCTCAG CCTCCCAAGTAGCTGGGACTACAGGCACCTGCCACCATGCCCAGCTAATTTTTTTTTTTTCAGTAGAGACAGGGTCTCACCATGTTAGCC AGGATGGTCTTGATCTGACCTCGTGATCCGCCGACCTCGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACTGCGCCTGGCCAAGA ATGGACATTTTTTAAAAAAACATCAGTACTTCCTACCACTGCTGCATGAGTATAATGCTCCGGAATTATCAGAAAGCATAATGCAGAAAT ACGAATTAGTGGAACTTAATCATGTGCCATATAAGCTTACCTAACAAACAGTTATATCCCTATTCCTCAACTGAATGTCTTTCAATAAAT AAGAATTTATCATTTATTTTCTGCAACTTTTTTATGTCTCATTCTTTAAACATTAAAAACCCTTAATATTTTAACAAAAATTTCTTGATT AGAGGCACAGTGAAAAAGAAGTCAAAAAAAAAAGTTCTACTTTTCATCAGTGCTATTAAAGGTGGCAGCAAATGTAAATCTTGGCTGAAT GGTCTTAATTACTCATTAAACCACAGTCAGAAAGACATATAGGTGCTATTTGGGAAAACTTTTTATTACCTAGGATGGGGTTTCTCTAAT TGCTAATCACAACCCCACTGGGTCATGTTTGACATTTTATAATGAAAATAAAACAGAAAGTGCCATAGTATGTTACAGAAAGCAAAGATG AGTATTGTTTCTCAAAGCCTTTGCTTTATGTATTTATACACATACTCATTCATATCTATCTATATATATAGAGAGAGATAGTGGTTCACA GTAATCATACAAAGTCTTTATTCCATCCACTATTATAAACATTTCTATTAAAACTAAAACTGGGCTCTATGTAAAAACCCCAAAGATACA CACACAAAAAAAATCTGTTTGTTAGAACTCAAGTGAATTCAGTAAAGTTGCAGAATACAAAATCAACATACAAAAAGCATTAGCATTTTT ATACATAAATAATGAAAATAATGACCTAACTGAAAAATTAAGATGCCATTTATGATAGCATAAAAAAAATACTTACTTAGGAATAAATTT AACACCAAGGCAGTAAAAGATCTGTATGTACACTGAAAACTATGAAACACTGATGAAAGAAAGACACAAATAAATGGAAAGGTATCCCGT GCTCATGGATCAGAATAATACTGTTAAAATGGTCACACTACCCAAAGCAATTCAGAATCAATGCAATCCTATCAAAATTCCAATGGCATT ATTTACACAAACAGAAAAAAATCCTAAAATTCATATGTAACGATAAAAGACCCTGAATAGGCAAAAGAATACTGAGGAAAAAATGTTGGA GACATCACATTTCCTAATTATAAATTATACTACAAAACTATAGTAATCAAGACAGTATGGTACTGGTATAAAAACACATACACAGGCCAG TGGGACAGAAGAAAGAGTCCAGATATAAATCCAAACATACACAGTCAACTAATTTTTGACAAAGACACCAAGAAGACACATCGGGGAAAG AACAGTCTTCATTAAGTGTTCTTAATGAAGATGCTGGGAAAACTGCACTTCCACATGCAAAACAATGAAATCAGACCCTTATCTTAGACC TACACAACAATCAATTCAAAATGGATAAAAGACCTAAATGTAAGACCAGAAACTATAGAAGAGAACATAGGAGAAAAGTTCCTGGACACT GACCCTTGGCAATGATTTTTTGGATATCACACCAAAAGCTCAGTCAACAAAAACAAAAACAAATGTGACTACATCAAACCAAAAAGCTTC >In-frame_NUDCD1_ENST00000427660_chr8_110334538_-_TMEM184C_ENST00000508208_chr4_148544985_+_1119nt AGTACTTCATAGACTTTATCATACTTCGTAGCATCCAGTATGTTTTCTTTGCTAAGATTATTGATTTTGTATTGAAGGGTCCCATGTCCA TCGTTTTCAATGCTTTATCTCCAGGGTTGGAGCATGCCTGCTGTGGCAGAGGTAAAACTTCGAGATGATCAATATACACTGGAACACATG CATGCTTTTGGAATGTATAATTACCTGCACTGTGATTCATGGTATCAAGACAGTGTCTACTATATTGATACCCTTGGAAGAATTATGAAT TTAACAGTAATGCTGGTTGGAATACACACCAAGGCTTGGTTTATTGCTGGAATCTTTTTGCTGTTGACTATTCCTATATCACTGTGGGTG ATATTGCAACACTTAGTGCATTATACACAACCTGAACTACAAAAACCAATAATAAGGATTCTTTGGATGGTACCTATTTACAGTTTAGAT AGTTGGATAGCTTTGAAATATCCCGGAATTGCAATATATGTGGATACCTGCAGAGAATGCTATGAAGCTTATGTAATTTACAACTTTATG GGATTCCTTACCAATTATCTAACTAACCGGTATCCAAATCTGGTATTAATCCTTGAAGCCAAAGATCAACAGAAACATTTCCCTCCTTTA TGTTGCTGTCCACCATGGGCTATGGGAGAAGTATTGCTGTTTAGGTGCAAACTAGGTGTATTACAGTACACAGTTGTCAGACCTTTCACC ACCATCGTTGCTTTAATCTGTGAGCTGCTTGGTATATATGACGAAGGGAACTTTAGCTTTTCAAATGCTTGGACTTATTTGGTTATAATA AACAACATGTCACAGTTGTTTGCCATGTATTGTCTCCTGCTCTTTTATAAAGTACTAAAAGAAGAACTGAGCCCAATCCAACCTGTTGGC AAATTTCTTTGTGTAAAGCTGGTGGTTTTTGTTTCTTTTTGGCCTTAACCCCGAAACTGACTATACTGGAGAAGGAAAGGCCGTGTAAAG ACACAACAAGAAAGCAGAATCTGCAATCCAGGAAGAGAATCCTCACAAGAAACCAAACTTGCCAACACCTTGATCATGGTCTTCCAGCCT |
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FusionGenePPI for NUDCD1_TMEM184C |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NUDCD1 | USP36, NPM1, HECW2, ERP44, PDCD10, PLD3, TYMP, UBA5, DHX8, DHX38, DHX16, COPB1, COPG2, DHX40, ARCN1, DHX33, COPZ1, GBA, COPE, FUOM, COPA, COPB2, COPG1, DHX15, DNHD1, VWA8, SLC34A2, ERBB4, F12, LIPH, NTRK1, DHX32, ABCF2, FAM19A3, CCND2 | TMEM184C | SGK1, TCTN3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NUDCD1_TMEM184C |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NUDCD1_TMEM184C |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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