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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 24991

FusionGeneSummary for NT5E_MDM2

check button Fusion gene summary
Fusion gene informationFusion gene name: NT5E_MDM2
Fusion gene ID: 24991
HgeneTgene
Gene symbol

NT5E

MDM2

Gene ID

4907

4193

Gene name5'-nucleotidase ectoMDM2 proto-oncogene
SynonymsCALJA|CD73|E5NT|NT|NT5|NTE|eN|eNTACTFS|HDMX|hdm2
Cytomap

6q14.3

12q15

Type of geneprotein-codingprotein-coding
Description5'-nucleotidase5'-NTPurine 5-Prime-Nucleotidaseecto-5'-nucleotidaseE3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, hum
Modification date2018052020180527
UniProtAcc

P21589

Q00987

Ensembl transtripts involved in fusion geneENST00000369646, ENST00000257770, 
ENST00000369651, 
ENST00000462284, 
ENST00000356290, ENST00000540827, 
ENST00000258149, ENST00000428863, 
ENST00000393412, ENST00000258148, 
ENST00000544561, ENST00000393410, 
ENST00000393413, ENST00000517852, 
ENST00000545204, ENST00000350057, 
ENST00000360430, ENST00000299252, 
ENST00000348801, ENST00000478070, 
ENST00000544125, 
Fusion gene scores* DoF score2 X 1 X 2=410 X 7 X 6=420
# samples 29
** MAII scorelog2(2/4*10)=2.32192809488736log2(9/420*10)=-2.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NT5E [Title/Abstract] AND MDM2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNT5E

GO:0007159

leukocyte cell-cell adhesion

7595232

TgeneMDM2

GO:0000122

negative regulation of transcription by RNA polymerase II

9271120|17310983

TgeneMDM2

GO:0006511

ubiquitin-dependent protein catabolic process

11278372|15314173|16173922|17310983

TgeneMDM2

GO:0016567

protein ubiquitination

9450543|15878855|19656744|20153724

TgeneMDM2

GO:0031648

protein destabilization

9529249|10360174|15314173

TgeneMDM2

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

11278372

TgeneMDM2

GO:0034504

protein localization to nucleus

10360174

TgeneMDM2

GO:0042176

regulation of protein catabolic process

9153395

TgeneMDM2

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

9529249|10360174

TgeneMDM2

GO:0045184

establishment of protein localization

10360174

TgeneMDM2

GO:0045892

negative regulation of transcription, DNA-templated

9271120

TgeneMDM2

GO:0065003

protein-containing complex assembly

10608892|12915590

TgeneMDM2

GO:0071157

negative regulation of cell cycle arrest

9529249

TgeneMDM2

GO:0071480

cellular response to gamma radiation

16213212

TgeneMDM2

GO:0072717

cellular response to actinomycin D

15314173

TgeneMDM2

GO:1901797

negative regulation of signal transduction by p53 class mediator

16173922


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSARCTCGA-DX-A23Y-01ANT5Echr6

86160196

+MDM2chr12

69207334

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000369646ENST00000462284NT5Echr6

86160196

+MDM2chr12

69207334

+
In-frameENST00000369646ENST00000356290NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000540827NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000258149NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000428863NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000393412NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000258148NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000544561NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000393410NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000393413NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000517852NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000545204NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000350057NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000360430NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000299252NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000348801NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000478070NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369646ENST00000544125NT5Echr6

86160196

+MDM2chr12

69207334

+
In-frameENST00000257770ENST00000462284NT5Echr6

86160196

+MDM2chr12

69207334

+
In-frameENST00000257770ENST00000356290NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000540827NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000258149NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000428863NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000393412NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000258148NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000544561NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000393410NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000393413NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000517852NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000545204NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000350057NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000360430NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000299252NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000348801NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000478070NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000257770ENST00000544125NT5Echr6

86160196

+MDM2chr12

69207334

+
In-frameENST00000369651ENST00000462284NT5Echr6

86160196

+MDM2chr12

69207334

+
In-frameENST00000369651ENST00000356290NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000540827NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000258149NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000428863NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000393412NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000258148NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000544561NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000393410NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000393413NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000517852NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000545204NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000350057NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000360430NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000299252NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000348801NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000478070NT5Echr6

86160196

+MDM2chr12

69207334

+
5CDS-intronENST00000369651ENST00000544125NT5Echr6

86160196

+MDM2chr12

69207334

+

Top

FusionProtFeatures for NT5E_MDM2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NT5E

P21589

MDM2

Q00987

Hydrolyzes extracellular nucleotides into membranepermeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidaseactivities. {ECO:0000269|PubMed:21933152}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19210_21527437Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19243_30127437Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05210_21527322Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05243_30127322Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03210_2150266Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03243_3010266Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16210_21527322Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16243_30127322Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04210_2150297Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04243_3010297Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03210_215-92219Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03243_301-92219Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02210_2150219Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02243_3010219Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04210_215-102271Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04243_301-102271Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111210_21533498Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111243_30133498Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05210_215-102297Compositional biasNote=Poly-Ser
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05243_301-102297Compositional biasNote=Asp/Glu-rich (acidic)
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+1927_10727437DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+0527_10727322DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+0327_1070266DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+1627_10727322DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+0427_1070297DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+0327_107-92219DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+0227_1070219DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+0427_107-102271DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+0527_107-102297DomainNote=SWIB
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19179_18527437MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19190_20227437MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19466_47327437MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05179_18527322MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05190_20227322MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05466_47327322MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03179_1850266MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03190_2020266MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03466_4730266MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16179_18527322MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16190_20227322MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16466_47327322MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04179_1850297MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04190_2020297MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04466_4730297MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03179_185-92219MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03190_202-92219MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03466_473-92219MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02179_1850219MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02190_2020219MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02466_4730219MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04179_185-102271MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04190_202-102271MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04466_473-102271MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111179_18533498MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111190_20233498MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111466_47333498MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05179_185-102297MotifNuclear localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05190_202-102297MotifNote=Nuclear export signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05466_473-102297MotifNucleolar localization signal
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19210_30427437RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19242_33127437RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05210_30427322RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05242_33127322RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03210_3040266RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03242_3310266RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16210_30427322RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16242_33127322RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04210_3040297RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04242_3310297RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03210_304-92219RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03242_331-92219RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02210_3040219RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02242_3310219RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04210_304-102271RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04242_331-102271RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111210_30433498RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111242_33133498RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05210_304-102297RegionNote=ARF-binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05242_331-102297RegionNote=Region II
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19299_32827437Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19438_47927437Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05299_32827322Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05438_47927322Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03299_3280266Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03438_4790266Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16299_32827322Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16438_47927322Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04299_3280297Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04438_4790297Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03299_328-92219Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03438_479-92219Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02299_3280219Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02438_4790219Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04299_328-102271Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04438_479-102271Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111299_32833498Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111438_47933498Zinc fingerRING-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05299_328-102297Zinc fingerRanBP2-type
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05438_479-102297Zinc fingerRING-type

- In-frame and not-retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNT5Echr6:86160196chr12:69207334ENST00000257770+19500_506113575RegionNote=Substrate binding
HgeneNT5Echr6:86160196chr12:69207334ENST00000369651+18500_506113525RegionNote=Substrate binding
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+11127_10733498DomainNote=SWIB


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FusionGeneSequence for NT5E_MDM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_578aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVK
EHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRH
KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDE
VTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKK
TIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGK

>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_408aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEVTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGR

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_578aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVK
EHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRH
KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDE
VTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKK
TIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGK

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_408aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEVTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGR

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_578aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVK
EHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRH
KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDE
VTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKK
TIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGK

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_408aa
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGT
IWFTVYKGAEVAHFMNALRYDAMVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEVTQVTVTQAGESDTDSFEEDPEISLADTWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDTSQPSTSSSIITSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_1734nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAA
CGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAA
GAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAG
AACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCT
AGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCAC
AAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAA
TCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAG
TTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAG
GTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAA
TGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAA
GGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAA
ACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTAT
TCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAG
AGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAA
ACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATG

>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_1224nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGAT
CCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCC
CTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAA
GAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAA
GCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTT
GAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGA
CCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCC

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_1734nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAA
CGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAA
GAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAG
AACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCT
AGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCAC
AAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAA
TCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAG
TTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAG
GTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAA
TGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAA
GGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAA
ACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTAT
TCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAG
AGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAA
ACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATG

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_1224nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGAT
CCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCC
CTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAA
GAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAA
GCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTT
GAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGA
CCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCC

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_1734nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAA
CGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAA
GAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAG
AACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCT
AGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCAC
AAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAA
TCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAG
TTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAG
GTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAA
TGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAA
GGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAA
ACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTAT
TCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAG
AGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAA
ACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATG

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_1224nt
ATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACG
ATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGC
GTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACT
ATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTT
TTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGAT
CCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCC
CTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAA
GAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAA
GCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTT
GAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGA
CCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_7368nt
GCACTCGCCCGGCTCGCCCGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCT
CGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGAC
CAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGC
CGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTT
CATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTA
TACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTC
AAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGT
AGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCT
TGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGAC
AGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGC
TCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGT
AAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGA
TTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATAC
AGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACA
TTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGA
AAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAA
TGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCA
AGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTG
TGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCT
AAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGACCTGTCTATAAGA
GAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGTGAGAAAATGCCTCAATTCA
CATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGACTTGAATATGTAGCTCATC
CTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTTCTTAAATATGTATATGACA
TTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAG
CTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCACCACACCTGGCTAATTTTT
TGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAA
GTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAAAATGTGTGAAAGATTTAGT
TTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTGCAGTGTCATGATCTAGCAG
TCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACCACCATGCCCAGCTAATTTT
TGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGGTCACCCGCCTCGGCCTCCC
GAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTTTTTTTTTTTTTTTTTTTTT
TTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCTTCTGGGTTCAAG
CTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTTGTATTTTTAGTAAAGACAG
GGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAAAATGCTGGGATTACAGATG
TGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTCTTTCTAGGTTAAAAAAAAA
AAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAGGGTCTCCCTGTGTTGCCCA
GGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACAGGCGTTAGCCACCACACCC
GGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTTATCTGTGAAAATAGCCACC
ATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACACACAAAAAAATCCTTTATG
GGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTGGCCTGGGTTACATGGTTCC
CAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAAATTTGATAAACAGAATTGT
TATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTTCAAGAATGACAGGGTCAGC
ATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGCTCAGCACTGAGAAGTGTTA
GTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATTGTATAAACATAAATGTCAC
AAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAATAATGAGCTTACAGTGGATT
TGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAGTGAAGACAGTTGAAAAGAT
CAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCAAAGAAGTCAGGCAAAACTC
ATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAGACATGGCAGAGGTTTCCTA
AAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAAATTATTGACTTATTTTTTA
TATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGATGTTTGATCGCATCTCATT
GTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGTTAATGGTACTAGACAACAT
GTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATATGCCCTTTATTATAGAAGGG
AGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTCTTATTTTGGTTTATTAGTG
TCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTCTGACAGATAGTTGGGGATG
AGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAACTTGTCATTCCTGGTAGAA
CAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTGTGTGGGTTTTTTTTTTTTT
AAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCACTTTTAATGGGTACAGAGTT
AAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTAAAAGTACTAATCCCTTTGG
CCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAAATAAATGATATTTGAGCTG
ATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACAATTATGTATTTAACATTTA
AAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAGCAAAACAGTGAAAATAACC
ATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAACTGTAAGCTTAGAATAGGA
CTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTGTCTGTCTCAATAAATGGCC
AAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAACCAAGCAGAATCTCTTTTTT
TTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAGCTAGAACCTAGTAGAATCT
GTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATCTGTTTTTTTCTGAGGAGTA
TCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAAATTTAAATCTGCAAATGGA
TTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAAATGATTAAGAATTGTTTCA
AGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTGGGTAACAAAAGGCACAAGT
CTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTTGAAGCAGTTGGGAGCCTCC
AATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTCTCTTAGGTCACATGGCAGC
CTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCACCGTACCACTTGTCAGCGTG
AAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTCTTGATTGTGAGGCACAAAT
GTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGGGACTAGCTTTTGGCATTAT
ATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTTGCTCTGTGGCTCAGGCTGG
AGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGCCTCCCAAGTAGCTGGGGTT
AGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCAGGCTGGGCTCAAACTCCTG
ACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCCTAATAAGGGTTTTAAAGAT
AATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAGTTGCGCTTTATGGGTGGAT
GCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAAGTTTGTGATCATATTGTCT
ACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGATATCTGAAAGCACCAGCAC

>In-frame_NT5E_ENST00000369646_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_6855nt
GCACTCGCCCGGCTCGCCCGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCT
CGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGAC
CAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGC
CGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTT
CATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTA
TACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGA
ATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGT
TACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATG
CAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAA
AGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAA
TGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATC
AACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATC
TAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCT
TATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAAC
TTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACA
TATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTA
CTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGG
TTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAG
TGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACA
GTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGAC
CTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGA
TATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCC
AGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTAC
AGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGAC
CTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTT
TAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGC
TCACTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAG
CTGATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCT
CAGCCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCT
CCAAAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAAC
AATAGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAA
GTAGGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGA
GTAATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGC
CCTTTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAA
GTACCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAG
TTAATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCA
TCATTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGG
CCCATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAG
GTGTTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAG
CAACTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAAC
TACTGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGT
TCAGGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTA
ACAGGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTT
AGAACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACA
GATAATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTA
CGCTATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTG
CAGTAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGAT
TTTAATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCT
TTTAATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATA
CTAAGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTT
GCAATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCA
CACAAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGAC
CTCCAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGT
TCTTGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACA
CCATATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATA
TGAATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAA
AATCAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCT
CTCTCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACT
TCAGCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGA
TAATATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAAC
CAAGCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCT
ATTTTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGT
GTTGAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATA
TCATATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCA
CTGGGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTC
TCCCTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTT
GGGCTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAG
CTGGGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTA
AGCCAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGA
GACGGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGT
TCTGCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCAC
TATGTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGC
CACGCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGA
AAAGTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAA
ATTGTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATAC
TTTGAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAA

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_7368nt
GCACTCGCCCGGCTCGCCCGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCT
CGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGAC
CAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGC
CGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTT
CATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTA
TACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTC
AAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGT
AGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCT
TGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGAC
AGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGC
TCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGT
AAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGA
TTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATAC
AGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACA
TTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGA
AAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAA
TGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCA
AGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTG
TGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCT
AAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGACCTGTCTATAAGA
GAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGTGAGAAAATGCCTCAATTCA
CATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGACTTGAATATGTAGCTCATC
CTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTTCTTAAATATGTATATGACA
TTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAG
CTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCACCACACCTGGCTAATTTTT
TGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAA
GTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAAAATGTGTGAAAGATTTAGT
TTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTGCAGTGTCATGATCTAGCAG
TCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACCACCATGCCCAGCTAATTTT
TGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGGTCACCCGCCTCGGCCTCCC
GAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTTTTTTTTTTTTTTTTTTTTT
TTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCTTCTGGGTTCAAG
CTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTTGTATTTTTAGTAAAGACAG
GGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAAAATGCTGGGATTACAGATG
TGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTCTTTCTAGGTTAAAAAAAAA
AAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAGGGTCTCCCTGTGTTGCCCA
GGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACAGGCGTTAGCCACCACACCC
GGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTTATCTGTGAAAATAGCCACC
ATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACACACAAAAAAATCCTTTATG
GGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTGGCCTGGGTTACATGGTTCC
CAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAAATTTGATAAACAGAATTGT
TATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTTCAAGAATGACAGGGTCAGC
ATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGCTCAGCACTGAGAAGTGTTA
GTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATTGTATAAACATAAATGTCAC
AAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAATAATGAGCTTACAGTGGATT
TGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAGTGAAGACAGTTGAAAAGAT
CAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCAAAGAAGTCAGGCAAAACTC
ATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAGACATGGCAGAGGTTTCCTA
AAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAAATTATTGACTTATTTTTTA
TATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGATGTTTGATCGCATCTCATT
GTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGTTAATGGTACTAGACAACAT
GTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATATGCCCTTTATTATAGAAGGG
AGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTCTTATTTTGGTTTATTAGTG
TCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTCTGACAGATAGTTGGGGATG
AGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAACTTGTCATTCCTGGTAGAA
CAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTGTGTGGGTTTTTTTTTTTTT
AAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCACTTTTAATGGGTACAGAGTT
AAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTAAAAGTACTAATCCCTTTGG
CCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAAATAAATGATATTTGAGCTG
ATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACAATTATGTATTTAACATTTA
AAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAGCAAAACAGTGAAAATAACC
ATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAACTGTAAGCTTAGAATAGGA
CTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTGTCTGTCTCAATAAATGGCC
AAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAACCAAGCAGAATCTCTTTTTT
TTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAGCTAGAACCTAGTAGAATCT
GTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATCTGTTTTTTTCTGAGGAGTA
TCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAAATTTAAATCTGCAAATGGA
TTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAAATGATTAAGAATTGTTTCA
AGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTGGGTAACAAAAGGCACAAGT
CTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTTGAAGCAGTTGGGAGCCTCC
AATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTCTCTTAGGTCACATGGCAGC
CTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCACCGTACCACTTGTCAGCGTG
AAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTCTTGATTGTGAGGCACAAAT
GTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGGGACTAGCTTTTGGCATTAT
ATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTTGCTCTGTGGCTCAGGCTGG
AGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGCCTCCCAAGTAGCTGGGGTT
AGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCAGGCTGGGCTCAAACTCCTG
ACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCCTAATAAGGGTTTTAAAGAT
AATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAGTTGCGCTTTATGGGTGGAT
GCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAAGTTTGTGATCATATTGTCT
ACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGATATCTGAAAGCACCAGCAC

>In-frame_NT5E_ENST00000257770_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_6855nt
GCACTCGCCCGGCTCGCCCGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCT
CGCCCTGGGCGCGGTGCTGTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGAC
CAGCGAGGACTCCAGCAAGTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGC
CGAACCCAACGTGCTGCTGCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTT
CATGAACGCCCTGCGCTACGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTA
TACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGA
ATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGT
TACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATG
CAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAA
AGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAA
TGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATC
AACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATC
TAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCT
TATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAAC
TTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACA
TATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTA
CTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGG
TTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAG
TGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACA
GTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGAC
CTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGA
TATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCC
AGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTAC
AGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGAC
CTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTT
TAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGC
TCACTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAG
CTGATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCT
CAGCCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCT
CCAAAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAAC
AATAGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAA
GTAGGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGA
GTAATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGC
CCTTTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAA
GTACCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAG
TTAATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCA
TCATTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGG
CCCATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAG
GTGTTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAG
CAACTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAAC
TACTGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGT
TCAGGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTA
ACAGGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTT
AGAACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACA
GATAATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTA
CGCTATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTG
CAGTAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGAT
TTTAATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCT
TTTAATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATA
CTAAGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTT
GCAATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCA
CACAAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGAC
CTCCAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGT
TCTTGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACA
CCATATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATA
TGAATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAA
AATCAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCT
CTCTCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACT
TCAGCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGA
TAATATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAAC
CAAGCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCT
ATTTTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGT
GTTGAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATA
TCATATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCA
CTGGGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTC
TCCCTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTT
GGGCTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAG
CTGGGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTA
AGCCAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGA
GACGGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGT
TCTGCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCAC
TATGTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGC
CACGCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGA
AAAGTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAA
ATTGTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATAC
TTTGAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAGTAACAAATTATAAAATGAGCTAACAAACGAAAGGCAAAATAA

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000462284_chr12_69207334_+_7350nt
CGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCT
GTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAA
GTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCT
GCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTA
CGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCT
TTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGA
TTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGA
ATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGA
AGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGA
ATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGA
GATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGA
TTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGA
AGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGA
TCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCCCTTCCATCACATTGCAACAGATGTTGGGC
CCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGA
AGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATGTGTTGAGGAAAATGATGATAAAATTACACA
AGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGATGTGAAAGAGTT
TGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAAGGTCG
ACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCC
CTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGACCTGTCTATAAGAGAATTATATATTTCTAAC
TATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGTGAGAAAATGCCTCAATTCACATAGATTTCTTCTCTTT
AGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGACTTGAATATGTAGCTCATCCTTTACACCAACTCCTAA
TTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTTCTTAAATATGTATATGACATTTAAATGTAACTTATTA
TTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCG
CACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCACCACACCTGGCTAATTTTTTGTACTTTTAGTAGAGAC
AGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCA
TGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAAAATGTGTGAAAGATTTAGTTTTTTGTTTTTTTGTTTG
TTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTGCAGTGTCATGATCTAGCAGTCTCCGCTTCCCGGGTTC
AAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGAT
AGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGGTCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTGCAG
ATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCT
TGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCTTCTGGGTTCAAGCTATTCTCCTGCCTCAGC
CTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTAGCC
AGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAAAATGCTGGGATTACAGATGTGAGGCACCTGGCCTCAG
ATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTCTTTCTAGGTTAAAAAAAAAAAGGCTCTTATATTTGGT
GCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTCGAACTCCT
GGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACAGGCGTTAGCCACCACACCCGGCTGTAAAAATGTACTT
ATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTTATCTGTGAAAATAGCCACCATTTACCCGTAAGACAAA
ACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACACACAAAAAAATCCTTTATGGGATTTAATGGAATCTGT
TGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTGGCCTGGGTTACATGGTTCCCAGCCTAGGTTTCAGACT
TTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAAATTTGATAAACAGAATTGTTATTTAAAAACTAACTGG
AAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTTCAAGAATGACAGGGTCAGCATGTGGAATTCCAAGATA
CCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGCTCAGCACTGAGAAGTGTTAGTTTCTTTGGGACCCATC
TACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATTGTATAAACATAAATGTCACAAAAACTTTAAAAGAAGT
GCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAATAATGAGCTTACAGTGGATTTGAATTTGAAAAATATAG
TAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAGTGAAGACAGTTGAAAAGATCAAACAAATGCCAAGCTA
TATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCAAAGAAGTCAGGCAAAACTCATCTTGACCCCTGTTGCA
GGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAGACATGGCAGAGGTTTCCTAAAAATCTCATTATCTATA
ACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAAATTATTGACTTATTTTTTATATAAGGTCACTCCGATG
AAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGATGTTTGATCGCATCTCATTGTTAACTCTTTACTGATA
TGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGTTAATGGTACTAGACAACATGTAATTAATGACATTCAA
AAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATATGCCCTTTATTATAGAAGGGAGGATATAAGGAACCAAC
AGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTCTTATTTTGGTTTATTAGTGTCTTAGAACAAAATGGCC
TTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTCTGACAGATAGTTGGGGATGAGAGCCGAATAAGGTTTG
CCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAACTTGTCATTCCTGGTAGAACAAGCTTTATTTTTCGAG
CCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTGTGTGGGTTTTTTTTTTTTTAAAGCCACACAATAATTT
TGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCACTTTTAATGGGTACAGAGTTAAATTTGAAGGAATAAGT
TCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTAAAAGTACTAATCCCTTTGGCCATTTATTGAGAGAGAG
AGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAAATAAATGATATTTGAGCTGATGGGTGTGCTAATTACA
CTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACAATTATGTATTTAACATTTAAAATTTCTAATATAAGTA
TCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAGCAAAACAGTGAAAATAACCATCTTGATTTAGTGTTTT
TCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAACTGTAAGCTTAGAATAGGACTGAGGTAATTCTGCACA
GCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTGTCTGTCTCAATAAATGGCCAAAGGGATTAGTAGTTTA
CCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAACCAAGCAGAATCTCTTTTTTTTGGAGGTCCTCGAAGCA
TTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAGCTAGAACCTAGTAGAATCTGTTTTTTTCCTTTGGAGG
TCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATCTGTTTTTTTCTGAGGAGTATCGGTAGCATAAATGTGA
TTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAAATTTAAATCTGCAAATGGATTCAACATGTTTATGGGT
TATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAAATGATTAAGAATTGTTTCAAGAATGCAATTATTTGAT
CTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTGGGTAACAAAAGGCACAAGTCTGAATGTGTTTCTTTTT
CTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTTGAAGCAGTTGGGAGCCTCCAATGAGAGCAACTTGAGA
GAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTCTCTTAGGTCACATGGCAGCCTGGCCTAAGTGATCGTG
AATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCACCGTACCACTTGTCAGCGTGAAAAGTAAGATTGTAATT
GCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTCTTGATTGTGAGGCACAAATGTAAGTACATCAGAAAAA
AACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGGGACTAGCTTTTGGCATTATATAATTAAGATTTTTTAA
ATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTTGCTCTGTGGCTCAGGCTGGAGTACAGTGGTGCAATCT
TGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGCCTCCCAAGTAGCTGGGGTTAGAGCACCCTGTCACCAC
GCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCAGGCTGGGCTCAAACTCCTGACCTCAAGTGATCTGCCC
GCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCCTAATAAGGGTTTTAAAGATAATTAGTGTGTAGGTCTG
TAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAGTTGCGCTTTATGGGTGGATGCTGAATTACATTTTGAT
TTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAAGTTTGTGATCATATTGTCTACCATGTAGCCAGCTTTC
AATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGATATCTGAAAGCACCAGCACTTGGAAGGTGTTCAGAAG

>In-frame_NT5E_ENST00000369651_chr6_86160196_+_MDM2_ENST00000356290_chr12_69207334_+_6837nt
CGCTTTCGCACCCAGTTCACGCGCCACAGCTATGTGTCCCCGAGCCGCGCGGGCGCCCGCGACGCTACTCCTCGCCCTGGGCGCGGTGCT
GTGGCCTGCGGCTGGCGCCTGGGAGCTTACGATTTTGCACACCAACGACGTGCACAGCCGGCTGGAGCAGACCAGCGAGGACTCCAGCAA
GTGCGTCAACGCCAGCCGCTGCATGGGTGGCGTGGCTCGGCTCTTCACCAAGGTTCAGCAGATCCGCCGCGCCGAACCCAACGTGCTGCT
GCTGGACGCCGGCGACCAGTACCAGGGCACTATCTGGTTCACCGTGTACAAGGGCGCCGAGGTGGCGCACTTCATGAACGCCCTGCGCTA
CGATGCCATGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCT
TGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCT
CGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGG
GGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCC
CCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAA
AGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAGAGAGTCATG
TGTTGAGGAAAATGATGATAAAATTACACAAGCTTCACAATCACAAGAAAGTGAAGACTATTCTCAGCCATCAACTTCTAGTAGCATTAT
TTATAGCAGCCAAGAAGATGTGAAAGAGTTTGAAAGGGAAGAAACCCAAGACAAAGAAGAGAGTGTGGAATCTAGTTTGCCCCTTAATGC
CATTGAACCTTGTGTGATTTGTCAAGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATG
TGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGAC
CTGTCTATAAGAGAATTATATATTTCTAACTATATAACCCTAGGAATTTAGACAACCTGAAATTTATTCACATATATCAAAGTGAGAAAA
TGCCTCAATTCACATAGATTTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGTGGAATAGTGAATACTTACTATAATTTGACTTGAAT
ATGTAGCTCATCCTTTACACCAACTCCTAATTTTAAATAATTTCTACTCTGTCTTAAATGAGAAGTACTTGGTTTTTTTTTTTCTTAAAT
ATGTATATGACATTTAAATGTAACTTATTATTTTTTTTGAGACCGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTG
GCTCACTGCAAGCTCTGCCTCCCGGGTTCGCACCATTCTCCTGCCTCAGCCTCCCAATTAGCTTGGCCTACAGTCATCTGCCACCACACC
TGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCT
CGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCGGCCTAAATGTCACTTAGTACCTTTGATATAAAGAGAAAATGTGT
GAAAGATTTAGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTGTTTGTTTTGAGATGAGTCTCTCTGTCGCCCAGGCTGGAGTGCAGTGTC
ATGATCTAGCAGTCTCCGCTTCCCGGGTTCAAGCCATTCTCCTGGCTCAGCCTCTGGAGCAGCTGGGATTACAGGCATGCACCACCATGC
CCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGGCTGGTCACGAACTCCTGACCTCAAGTGAGGTCACCCG
CCTCGGCCTCCCGAAGTGCTGGGATTGCAGATGTGAGCCACCATGTCCAGCCAAGAATTAGTATTTAAATTTTAGATACTCTTTTTTTTT
TTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCACCCATGCTAGAGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCT
TCTGGGTTCAAGCTATTCTCCTGCCTCAGCCTTCCAAGTAACTGGGATTACAGGCATGTACCACCATACCAGCTGATTTTTTTGTATTTT
TAGTAAAGACAGGGTTTCACCATGTTAGCCAGGCTGATCTTGAACTCCTAAACTCAAGTGATCTACTCACCTCAGCCTCCCAAAATGCTG
GGATTACAGATGTGAGGCACCTGGCCTCAGATTTTTGATACTCTTAAACCTTCTGATCCTTAGTTTCTCTCTCCAAAATACTCTTTCTAG
GTTAAAAAAAAAAAGGCTCTTATATTTGGTGCTATGTAAATGAAAATGTTTTTTAGGTTTTCTTGATTTAACAATAGAGACAGGGTCTCC
CTGTGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGAGATCCTCCTGTCTTGGCCTCGCAAAGTGCTAAGTAGGATTACAGGCGTTA
GCCACCACACCCGGCTGTAAAAATGTACTTATTCTCCAGCCTCTTTTGTATAAACCATAGTAAGGGATGGGAGTAATGATGTTATCTGTG
AAAATAGCCACCATTTACCCGTAAGACAAAACTTGTTAAAGCCTCCTGAGTCTAACCTAGATTACATCAGGCCCTTTTTCACACACAAAA
AAATCCTTTATGGGATTTAATGGAATCTGTTGTTTCCCCCTAAGTTGAAAAACAACTCTAAGACACTTTAAAGTACCTTCTTGGCCTGGG
TTACATGGTTCCCAGCCTAGGTTTCAGACTTTTGCTTAAGGCCAGTTTTAGAAACCCGTGAATTCAGAAAAGTTAATTCAGAAATTTGAT
AAACAGAATTGTTATTTAAAAACTAACTGGAAAGATTGTTAAGTTCTTTCTGAATTATTCAGAAATTATGCATCATTTTCCTTCAAGAAT
GACAGGGTCAGCATGTGGAATTCCAAGATACCTCTTGACTTCCTCTCAAGCTCCGTGTTTGGTCAGTGGAGGCCCATCCGAGCTCAGCAC
TGAGAAGTGTTAGTTTCTTTGGGACCCATCTACCCTGACCACATCATGATGTTCATCTGCAGCTGTTGCAAGGTGTTCAGATTGTATAAA
CATAAATGTCACAAAAACTTTAAAAGAAGTGCAATTCTCAAAAGGTTAGGTGGACTAAAGCATTCTGTAAAGCAACTGCTAATAATGAGC
TTACAGTGGATTTGAATTTGAAAAATATAGTAACAAGCCTGTCAAATATCTGCAAGAACTATGGAATAAAACTACTGATGCAGTGAAGAC
AGTTGAAAAGATCAAACAAATGCCAAGCTATATTTATAATGAACAAATTCAAGAAAAAGGACTACGGAAAGTTCAGGACATCAAAGAAGT
CAGGCAAAACTCATCTTGACCCCTGTTGCAGGCAAAGGAACGCAGCTGGAAGAAAAGATGATATAACAGTTAACAGGATGCAGACATGGC
AGAGGTTTCCTAAAAATCTCATTATCTATAACCATTTCTATATTTACATTTGAAAATCTCCTTTGGAGACTTAGAACCTCTAAATTATTG
ACTTATTTTTTATATAAGGTCACTCCGATGAAAGGTGATTACAAAATCATCTACATTGCTGTCTACAAAACAGATAATATGGATGTTTGA
TCGCATCTCATTGTTAACTCTTTACTGATATGTTTGTAAATACAGAAGTGAAATGTGGACATAAAATAGTTACGCTATTTGGTTAATGGT
ACTAGACAACATGTAATTAATGACATTCAAAAATTTATGGCTAGTGATATATATAAAGTAAAATTTTCTTTGCAGTAAAATATGCCCTTT
ATTATAGAAGGGAGGATATAAGGAACCAACAGTTTGTATGAAAATAGCTCAAATAATATCTTTTATTTTGATTTTAATATTTCTTATTTT
GGTTTATTAGTGTCTTAGAACAAAATGGCCTTATATAATGAAGCCTAGTTATGCTGGACTGTTTTGATCTCTTTTAATTGTTCTGACAGA
TAGTTGGGGATGAGAGCCGAATAAGGTTTGCCTGAAATAACTGACACTATATAATTTCTGCTTTGGCAAATACTAAGTTCTAACTTGTCA
TTCCTGGTAGAACAAGCTTTATTTTTCGAGCCTAGCAATGATCTAGAAGCAGATGTTATCTCAGTGCCTTTTGCAATTTGTTGTGTGGGT
TTTTTTTTTTTTAAAGCCACACAATAATTTTGGAAAACAATGTATGGGTAGAACATGTGTCTGTTAATTGCACACAAAACCACTTTTAAT
GGGTACAGAGTTAAATTTGAAGGAATAAGTTCTAGCTGAAGTATTATGAACTCCAAATAATGCTTTGAGGACCTCCAAAGGTAAAAGTAC
TAATCCCTTTGGCCATTTATTGAGAGAGAGAGAGAGAGAGAGTAGGGTGACTATAGTTAATGTATTGAATGTTCTTGCTACAAATAAATG
ATATTTGAGCTGATGGGTGTGCTAATTACACTGATTTGATCAATACCCATTGTATGTGAAACAGTACATACACCATATTTACAATTATGT
ATTTAACATTTAAAATTTCTAATATAAGTATCTCTCAAACTGTGGATTAACTTCTTGATTTATATTTAAATATGAATCTTAAGCAAAACA
GTGAAAATAACCATCTTGATTTAGTGTTTTTCTCCCATATGTGAATTGTATATACTTAGGTGAAGACAATAAAATCAACTGAACTGTAAG
CTTAGAATAGGACTGAGGTAATTCTGCACAGCAACTTTACTAATGGTACATTGTTGCTTCAAAACTCTCTCTCTCTCTCTCTGTCTGTCT
CAATAAATGGCCAAAGGGATTAGTAGTTTACCTGTGGAGGTCCTCCAAGCATTATTTGGAGTTGATAATACTTCAGCTACAACCAAGCAG
AATCTCTTTTTTTTGGAGGTCCTCGAAGCATTATTTGGAGTTGATAATACTTCAGCTTCAATTTGGAGTTGATAATATTTCAGCTAGAAC
CTAGTAGAATCTGTTTTTTTCCTTTGGAGGTCCTCAAAGCATTATTGGAGTTCATAATACTGAAGCTAGAACCAAGCAGAATCTGTTTTT
TTCTGAGGAGTATCGGTAGCATAAATGTGATTATAAACATAGTACACTTGATATATGGAGGCAGTGACAGCTATTTTTACAAAATTTAAA
TCTGCAAATGGATTCAACATGTTTATGGGTTATTAAAATTGTCTGATTTCTTAGGTTCTTTATAGTACACGTGTTGAAAATAAATGATTA
AGAATTGTTTCAAGAATGCAATTATTTGATCTTAAATTTTTATGAGTTGTTAAAATAGAAATTATTTGAATATCATATATTTGGGTAACA
AAAGGCACAAGTCTGAATGTGTTTCTTTTTCTGGAATGGCCATGCCTGCCCACTTTAGAAATACAAATATCACTGGGCAGCTTGAAGCAG
TTGGGAGCCTCCAATGAGAGCAACTTGAGAGAATGATGTTGCAAGTTAGTAGGAGTAAGAAATGCTGTGTTCTCCCTGTCTTCTCTTAGG
TCACATGGCAGCCTGGCCTAAGTGATCGTGAATGGTCTATAAGGGAGGTAGCTGGGACAGGGAGGGGAGTTTGGGCTAGCCACCGTACCA
CTTGTCAGCGTGAAAAGTAAGATTGTAATTGCCTGTTTAGTTTTCTGCCTCATCTTTGAAAGTTCCACCAAGCTGGGAACCTCTTGATTG
TGAGGCACAAATGTAAGTACATCAGAAAAAAACAAAAAAACTGGCTTTAAAGCAGGAGCTTGTGGGCCCCTAAGCCAGACGGGGACTAGC
TTTTGGCATTATATAATTAAGATTTTTTAAATCCTTAATAAGGGTTTTATTTTATTTTTATTTATTTTTTGAGACGGAGTCTTGCTCTGT
GGCTCAGGCTGGAGTACAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTGTGTTCAAGTGGTTCTGCTTCAGCCTCCCAA
GTAGCTGGGGTTAGAGCACCCTGTCACCACGCCCCGCTAATTTTTGTATTTCTAGCAGAGATGAAGTTTCACTATGTTGGCCAGGCTGGG
CTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCCCCCAAAGTGCTGTGATTACAGGCGTGAGCCGCCACGCCCAGCCTAATAAG
GGTTTTAAAGATAATTAGTGTGTAGGTCTGTAGGCTTATGATGGTAACCACAAGTTGTTAATGGCATTGTGAAAAGTTTTTAGTTGCGCT
TTATGGGTGGATGCTGAATTACATTTTGATTTGATACTTATAAAAAGAAAAAGTATTTCTTCAGCTTAAAAAATTGTTTAAAAGTTTGTG
ATCATATTGTCTACCATGTAGCCAGCTTTCAATTATATGTAAGAGGGACTTTTTGACATTTACAAATAATACTTTGAGGTAGATATCTGA


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FusionGenePPI for NT5E_MDM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
NT5EAFF1, SLC30A5, NDUFA2, SYNJ2BP, PCDH7, TMEM177, XPO7, CHD1L, FLVCR1, ATR, RPTOR, GLMN, RDH13, SCAMP1, USP22, HSDL1, RFC2, RAB9A, DNAAF5, MTOR, GHITM, PDS5A, RHOG, TNPO2, PLAA, SLC7A2, ARL2, STEAP3, SLC41A1, ADIPOR1, SLC47A1, ARF5, DEGS1, SAR1B, USP36, GJA1, SLC44A1, GNL3L, SLC16A2, SLC26A6, ARL8A, SLC6A8, VANGL2, NR2F2, CYP2S1, USP3, CXCR4, TMEM192MDM2TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19170_30627437MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05170_30627322MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03170_3060266MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16170_30627322MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04170_3060297MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03170_306-92219MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02170_3060219MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04170_306-102271MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111170_30633498MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05170_306-102297MTBP
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19150_23027437PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05150_23027322PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03150_2300266PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16150_23027322PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04150_2300297PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03150_230-92219PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02150_2300219PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04150_230-102271PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111150_23033498PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05150_230-102297PYHIN1 and necessary for interaction with RFFL and RNF34
TgeneMDM2chr6:86160196chr12:69207334ENST00000258149+19223_23227437USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000299252+05223_23227322USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000348801+03223_2320266USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000356290+16223_23227322USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000360430+04223_2320297USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000393412+03223_232-92219USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000393413+02223_2320219USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000428863+04223_232-102271USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000462284+111223_23233498USP7
TgeneMDM2chr6:86160196chr12:69207334ENST00000540827+05223_232-102297USP7


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for NT5E_MDM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneNT5EP21589DB00806Pentoxifylline5'-nucleotidasesmall moleculeapproved|investigational
TgeneMDM2Q00987DB01593ZincE3 ubiquitin-protein ligase Mdm2small moleculeapproved|investigational

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RelatedDiseases for NT5E_MDM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNT5EC0023893Liver Cirrhosis, Experimental1CTD_human
HgeneNT5EC0038356Stomach Neoplasms1CTD_human
HgeneNT5EC1859372Calcification of Joints and Arteries1CTD_human;ORPHANET;UNIPROT
TgeneMDM2C0007131Non-Small Cell Lung Carcinoma2CTD_human
TgeneMDM2C0007621Neoplastic Cell Transformation1CTD_human
TgeneMDM2C0019693HIV Infections1CTD_human
TgeneMDM2C0021364Male infertility1CTD_human
TgeneMDM2C0025202melanoma1CTD_human
TgeneMDM2C0032927Precancerous Conditions1CTD_human
TgeneMDM2C0033578Prostatic Neoplasms1CTD_human
TgeneMDM2C1458155Mammary Neoplasms1CTD_human