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Fusion gene ID: 24456 |
FusionGeneSummary for NLGN4Y_SHISA6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NLGN4Y_SHISA6 | Fusion gene ID: 24456 | Hgene | Tgene | Gene symbol | NLGN4Y | SHISA6 | Gene ID | 22829 | 388336 |
| Gene name | neuroligin 4 Y-linked | shisa family member 6 | |
| Synonyms | - | - | |
| Cytomap | Yq11.221 | 17p12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neuroligin-4, Y-linked | protein shisa-6protein shisa-6 homologshisa homolog 6 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8NFZ3 | Q6ZSJ9 | |
| Ensembl transtripts involved in fusion gene | ENST00000476359, ENST00000297967, | ENST00000432116, ENST00000441885, ENST00000409168, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 2 X 2 X 1=4 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: NLGN4Y [Title/Abstract] AND SHISA6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A48U-01A | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000476359 | ENST00000432116 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| 3UTR-3CDS | ENST00000476359 | ENST00000441885 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| 3UTR-3CDS | ENST00000476359 | ENST00000409168 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| In-frame | ENST00000297967 | ENST00000432116 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| In-frame | ENST00000297967 | ENST00000441885 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
| In-frame | ENST00000297967 | ENST00000409168 | NLGN4Y | chrY | 16835149 | + | SHISA6 | chr17 | 11459057 | + |
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FusionProtFeatures for NLGN4Y_SHISA6 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NLGN4Y | SHISA6 |
| Putative neuronal cell surface protein involved in cell-cell-interactions. | Involved in maintenance of high-frequency synaptictransmission at hippocampal CA3-CA1 synapses. Regulates AMPA-typeglutamate receptor (AMPAR) immobilization at postsynaptic densitykeeping the channels in an activated state in the presence ofglutamate and preventing synaptic depression. May play a role inself-renewal and differentiation of spermatogonial stem cells byinhibiting canonical Wnt signaling pathway.{ECO:0000250|UniProtKB:Q3UH99}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NLGN4Y_SHISA6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000432116_chr17_11459057_+_463aa MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQP PESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIH EQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILEKPRMNNILTSATEPYDLSFSRSFQNLAHLPPSYESAVKTNP SKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRILSDEQLLST ERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMSKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHH >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000441885_chr17_11459057_+_463aa MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQP PESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIH EQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILEKPRMNNILTSATEPYDLSFSRSFQNLAHLPPSYESAVKTNP SKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRILSDEQLLST ERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMSKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHH >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000409168_chr17_11459057_+_463aa MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQP PESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIH EQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILEKPRMNNILTSATEPYDLSFSRSFQNLAHLPPSYESAVKTNP SKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRILSDEQLLST ERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMSKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000432116_chr17_11459057_+_1389nt ATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTGTGGATAACT GCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGCCTAAGAACA CCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGGTTTCAGCCA CCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGATTCTTATTG CATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTTTACTTAAAC ATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAAGATATTCAT GAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGCAGCATTTTG GCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTGACATCAGCC ACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAGACCAACCCC AGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTGGCTGCCCGC GGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCCATGTCCCAG GACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTGCTCTCCACG GAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCGCACACGGAC GTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATACGCCACCCTG GGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCGGGCCACCAC >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000441885_chr17_11459057_+_1389nt ATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTGTGGATAACT GCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGCCTAAGAACA CCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGGTTTCAGCCA CCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGATTCTTATTG CATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTTTACTTAAAC ATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAAGATATTCAT GAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGCAGCATTTTG GCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTGACATCAGCC ACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAGACCAACCCC AGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTGGCTGCCCGC GGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCCATGTCCCAG GACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTGCTCTCCACG GAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCGCACACGGAC GTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATACGCCACCCTG GGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCGGGCCACCAC >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000409168_chr17_11459057_+_1389nt ATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTGTGGATAACT GCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGCCTAAGAACA CCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGGTTTCAGCCA CCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGATTCTTATTG CATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTTTACTTAAAC ATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAAGATATTCAT GAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGCAGCATTTTG GCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTGACATCAGCC ACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAGACCAACCCC AGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTGGCTGCCCGC GGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCCATGTCCCAG GACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTGCTCTCCACG GAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCGCACACGGAC GTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATACGCCACCCTG GGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCGGGCCACCAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000432116_chr17_11459057_+_7247nt TTTTCGAAAGACTTATCTTTCTGCAGGCTCGCCTCTGAGCTTTGTCTCCTTGGAGCCACCTCACTTAGACAGCTTCGGATGTGGATGCAG ATTTGAACCATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTG TGGATAACTGCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGC CTAAGAACACCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGG TTTCAGCCACCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGA TTCTTATTGCATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTT TACTTAAACATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAA GATATTCATGAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGC AGCATTTTGGCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTG ACATCAGCCACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAG ACCAACCCCAGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTG GCTGCCCGCGGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCC ATGTCCCAGGACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTG CTCTCCACGGAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCG CACACGGACGTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATAC GCCACCCTGGGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCG GGCCACCACACCTGCTACACAGCCAGCAAGACCGAAGTGACCGTGTGACCGGCGGGGCAGGGCCGGGGCTGCTGGGCGTGGCAGAGCAGA GCGGGGGCCGGGAGGGGCCAGGAGCAGAGCTTCTAGCCTTGCCACTCTCCCTTCCCTTGTCCCCTCTGTAGGAAGTGGGGGTGGGCCACC TTTGCCCAAAAAGCCATACCCCCGGGGACACAGCCCCGATGGCCTGGTCCAATACACTTAGACCCAGGACCAAGAGCAATCGCTCTTGCT CCTCCAGAAGAATCAGTGGGGAGTGAGGAGGGGGCTAGGCCCCATTCTCACCCCCGACCACCTTCACCAACTCCCTTTCCGTCCCGCGCC TCCTTCTCCCCATCCGGGGGACTCAGCTGCAGGTTCTGTCAGCAGAGAGACCCTTGCTTGACTGTGGTCTGAAGCTGCCTGGGTTTGAAG GGGCCAGCGGGTCCAATCAGTGGGCTGACCGGATAGGCTACTCGGTCTCATTCATTCATCTAGAACCGCATCACAGAAATCTCCTAGTGC CTAAAAACTGCCTGCTCGCTCTCTCAGAGCCAGGGAGCTGCTGTGTCCATAAGCACAATAATGATTCTTTTCTTGCCTGCTGGAACTCTC TGGTCCCCACTGAGTGACCCTTCCTTTGCTGACCCCTGAGGGCCCAACCCTGGCCCTGTGCCCCTCCCCTCAACTCCAGGACCAGGAGGG GTTCCCTTCCTTCAGCTGCCTCCCCATTGGTGGGAACTCCACCCCCTTCCAGCTGACTGCCCGCCCATAAGGACCCTGGGCCTGTCCTTT CAGCGGGCTGTGCTCCTTCCCTGGCCCTGAGGATTTCACCCTTGAGTTTTCTGGGGTTTTGGCTGTAGCCTTCGCAGAGGGGAGTAGCAA TGGGGTGCTGGCCCTCCCAGACACCCGATCATCTCCGCACTCCCTCCAGGCCTCTAGACCTGACCATGACTGCCACTCAGGCTGCCTTCT CCACCCCTGCTCTGCTCCCAGGAGGCACCTGCGGTGGCCAGAGAGCCAGGGTGGGGAGGGCCACTGTGATGTGCGGGGTCTCGGGCTCAA CATTCGCATCCTGCAGGGCTCCACCTGTTCCCACATGCACCTCCGGCAGGACCTAGACAGAAGTTTCTAGAGAGCAGCTTTTCAGCCCCC AGACAAGGAGGATGAGAGGTGGTTGTCCTGCATCCTCTCCGCTCATCCTTCCTTCCCCATCTCTGTCTACCTGCTCAGTTCAGAGATCAC TCCTACTGCCTGTGTCCCCTTCCCCCACATCCTCCCTGCAACTTTATTCCTCCTAGCTGATCCTTCAGATCCGTGCCTCCTCTGGATCAA AGGGACAAAGACCTATTAGCAAAAGCAAACAAAGGTCCTCCAGGCGACTGGCCTAGGGGCTAACTGGGCAGGTCCCCACAGCATCATCCC TTTGTGCAGGCACTGGGGTACCTGGTAGACCATGGTCCTCAGCTCTGTTGGGGGACCGCCACTGCCCGCCCACCTCAGCCTCTTCCCCGC CTCCAGCCTGGGGGTTGGCATGGTGTGACGGCCTCCTGGGGAGGTGACAGTGAATTCAGCAGCATCCGCTCCCCCAAGACCAGAGAGCCT GGTGGGGGAAAGAAGGGGTTCCCTCATTCTCAGGGCCAGGGCACCCGCTGGGTTGGGGCTGGGGGAATCAACTCCAGGCTATTGGGTGAA GGTGTGATCCTAAAAACAGTCAGATCCAACAGCAGTGCCCTTATAAATGGGGTTTTACCTGCCCTCAGTTCTGCACTCATGGCCCTTTAA AAAGGCGAGTGTAGAAGGAGAATTTATTGGTGTCAGCCCTGGAGATTTTTAATCTAACCAAGTCCACAAACCACAGAGAAAGCAATGGAC TGTGTCCTTTCACTGATTTCAAGAGTTCCAAAGCTCTCATCTCCTTCTCCCCTCTGCAGGGTGTGCCTCCCAACAGGAACAGGAAACCAT CACCCTGGATCTTAGGGGGATGGAGGCTGGGGGTTGTGAAAGCCACTGTCAGACCCCACACTGGGGATGCATTCCTGGAGTCGTGCGGCT GGAAGGCCAGGGACTACCCTCTCTGCTTTCCTCCCAACAGACACATAAACCTTCTTAAGGGCTGGTCCCCAGGGGTTTATAAGAGTTTGT TCCAGAAGGTGAGGCTAAGAGGGTTGGAAAGGAAGAAGTGAGTCTGAATAGAGCAGGTGGCTCCCAGCTGGGCCCCTGAGCCCAGCACCT TTGAATCGTCTAATCTGTGGCCATCCCTTGGAAGGCAGGATGCTGGTGGTGAGGGGAAAGGACCTGAGTGGCTGAGAATGCCCTTCCCAG GTGTCTACATGCAGGTATACACCAAACCAGAAAGCTGATCCCATCTCCAGTGTCAAAGCTTCTCAGCACCAAGTTCTCCAGCCCCCAGGG TGACACTTTTCCCCAGGGGTCCTCCCCAAGCCCTGTCTCTGACAGGGTTTCTGTCTCTCTCAGGGGTTGTTGATGAGTTGATTCCAAGAC ATTTCTCATCCCAGCCTTACCACTGTCTGGCTGAAAGGCTCTGATGTCAGTTGGGTTGGAAAATTCTACTGCAATGCTTACTTCTTTTCA AGGATTTCTTCTGCTTCACCTTTGGGTCTAGAAGCAAGGAATGAAGGGAGGGAGAGAGGGAGGGAGGGAGGGGAGGAGGGAAGAAAAAAG AAGTAGAGATAGGTCTACAGACTTGCTCCAATTCAGTCCCACATTTCAAAATCCAGAAAACTATGTCATAGCTGGGACAGAGAGGTATCC CATTTATTCAGCTGTCCCATCCATCTTCATGGAACAAGCAAAGCCACATCAATAGGCAAGTTCACGTAGCAGATAAAAGAGGCTTCTGGG GCTGGAACCTAGATGCCATGATTTCTAGCCCAACCAGGCTGGTGGCCTCTACCATACATAGAAGTACCATCCACCCTTACAGTAAAAGCC TCCCTCCTGCTCACAAAGGAAGCCTAAAGCCCAAGATTTCCCTCTCCTTGTTTTATTCATTTTTGCACATCTCTGTTGCTCTAACAGAAA TGAACTGGAATCTGCACAGGTTCTCTCCTGCCCTGAAAGTTCTGCCTGGTTTCCTTGGCCTCTGATGGCATTGAAGCTTTCACAATCCCT CCTGCATCTCCACCTTCCCTGTCTTGCTCCAGGCTCCTGGCTCCATGCCTTCCTGTGTCAAAAAGGCTTTGCCAAGAATTACTTCACCTC CTAACCAGGCTTCTGCCCTCAGGGCTCCCCCAGTGTCTTGGGAGTGTCTTGGGCCACACGACTGCCTCTTAGAAAGTTCCAACCTTGCCC CCAATTCAAATTTCTCCTCCCCTCTTTCCACTCTCCCTCCCAGAAACTCCTGATTTCCAGAAAACCTCAGATTTCCAGGCCAGGTCACTC ATTCCTTCCTCTCATCTCCCTCTTCCTCCATCTACCTTCCTCCATTCACCTTCCTCCATTCCTAATTTCTTTTCCCTGGTCTTGCTATAA TCTCCAGCTCTAAAAATCAGAGCTCTCAATGAAAACAATGGAAGAATAAGACATTCTTTCGGTCTTCTGTTTGCCTCACTGGTGTATCCT TCATCTCCTGCCCCTGTGAGTTGATACCCCAGTGCACGGAGCCAAGGGCTTTTCCCCTCTGAGCTCTGGGAGGGAAGGGAATGGAGCTCT GGGTTTGAGATGTCATGGCCTGTGATAGTCAGTTTGGTTCCTGCCACTAGCAAGTCCCCTGAAGCTCCCAACCCAGCCTGATGTTAGCCC AGAAGCTCCTGCTCTGGCCAAAGACTCCTATCCTTGAGGGCTCTCAGCCACTGCTCCAACACACTTGCCCCCTTCCTGCTTGTGTATGTC ACTTATCCTCCTTTGTCCACAAAGACTTGAGGGCCTCCTGAGTCTCCAAGCATGGAGGAATATCCATGCCAACATCCCTGCCATCAAACT CAATCCATTTTCTTCAGAGATACCTTGTCTGTCACCAGCCTCCAACTTCATATTCCTTCCACAGGCAACTGTGCACTTGACCCAAGGTAA AATGAAAGGGCTGCCAATCACTCGGACTCCAGAAGGTGCCTGCCCTGAGAAGAGCTGGCATGTTACCTCCCACATACATTTCCTGTCATC CTGTCCGAATCTGGGAAATTTTGCTCTGGAGTATTTTCAAGAAAGCGCATTGTGTTTTAATGAAGTATTTTTCAGGGTTCCAATGTTATT TTTTATAAATGCAGCATTTTAATGGCAGATTCAATATGAAGGACATGTCTTCCTGGGCTCTATATTTGATTTTGGAAGGCAGCATACTCT AGGAGAAAAAAAGCATAGGGCTGAGGCTCTGAAGACACAGCTTCCAGCCCTGGCTTTGTCTCCGAGGGGGAGTCATGTTCCCCACTCAGT GCCTCAGTTTCCCCATCTGTAAAATGAGGGGCTTTGACTAGATGAGCTCTGAAGTTTCATCCAGCTCTTACACTGTAGGGCTTTCATTCC CTGCCAGCACCTGCTCTCCCCGTTCCTCCCCACCTCCACTGAGCTGCACACATCCCACAATGCCTGCCCCACAGCGATGTCCTCAGATGT CCTGGACAGCCACCGCACTCCTCACTAGAGCCTGGGGTGGGCCTGATGGGCTCGGCCACCCAGGGATGCCCTCGTACCTGAAGTTTAAGG GCCTAACCATTCAATAGGTCACCAACTGTGTGCCATGGAAGCCCTCTTGTAAAGACACACCTAAACCATCCTAAGTGACTGTGGAATTCT GGGGAATTCTGAGTTTGGAGTTTCCATTTGGATACGGTCCTTATAGCTGGAGGGAGGCGGTTCCAATTTCAGAGAGGGAGCTGGCTGGAG AGAAAGGTCTGGAGGTTGGCCCATAAGGGCATGAAGTTTGTACTTGAGGGCAGCTGGGAAATTCATTTCAAGCTGCAGAGGAACGTGTTC ACAGGCTGTTGTGTGGCAATGAATGTCATGATAACCCACTCTGGAATATGTGTCCTGAAGACCAAGTCTGGACACTGAGGCTCCATTCCA ACTGGAGGAGGAGGCATCTCCATCTGGGCTGCTAGGAAGGGGCACTCATCCCATCCTAGTACCTTTGTAGCCCTTCGTCATGACACTACC GTCCTCCCGGTGAAGGCTTGTGAAGCAAGAATGGAGAGTCCAAGTTTGTGATATTCAAACCCATCTTGTAAATCAGCAAACACATTAACC TTCCATCAGTCAGAGAAATAATGTTGTGGCTGTGTGTTTCCTTAATGCTCTCCCTCCTGAGGGAGGAGAAGACCCTGCTCAACTTTGCTG CCCACCCTGCAGTGACCCCTGAATGCCACACCATGGGAGGACTCATTCATTGGCTTTGTAGTGGCAAATATTCCTCTAGTTCTATAACTC AACTAGACATTTTGTAGTAAAGAATTCTTGAAATTCTCTAATAAAAAGCAATTCTTACTGTAATATTTTTAGTTTGGGGACACAATTTCC TAAGGGGGGATTAATGAACATTTTTATGCATTAGCCCAATTTATGAATTCCATGTTTATTATATGGTAGTACTGATGAAAAGTACCTTTC TATCTGTATCTTTGCAGTTTCTTCGTTACTCATATGTAAGCCTCATGGTAAGCAGTGCTCTAGTAACTGCTTCTCTGTACAAATCTCATC GTTCTACTTACCTGTCAAAGCACATTCTACATGTACTGTAAACAGATACACTTTAGTAAGATTTAGTCTTAAGGATTTTTCCACTTTTGT >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000441885_chr17_11459057_+_7247nt TTTTCGAAAGACTTATCTTTCTGCAGGCTCGCCTCTGAGCTTTGTCTCCTTGGAGCCACCTCACTTAGACAGCTTCGGATGTGGATGCAG ATTTGAACCATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTG TGGATAACTGCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGC CTAAGAACACCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGG TTTCAGCCACCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGA TTCTTATTGCATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTT TACTTAAACATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAA GATATTCATGAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGC AGCATTTTGGCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTG ACATCAGCCACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAG ACCAACCCCAGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTG GCTGCCCGCGGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCC ATGTCCCAGGACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTG CTCTCCACGGAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCG CACACGGACGTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATAC GCCACCCTGGGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCG GGCCACCACACCTGCTACACAGCCAGCAAGACCGAAGTGACCGTGTGACCGGCGGGGCAGGGCCGGGGCTGCTGGGCGTGGCAGAGCAGA GCGGGGGCCGGGAGGGGCCAGGAGCAGAGCTTCTAGCCTTGCCACTCTCCCTTCCCTTGTCCCCTCTGTAGGAAGTGGGGGTGGGCCACC TTTGCCCAAAAAGCCATACCCCCGGGGACACAGCCCCGATGGCCTGGTCCAATACACTTAGACCCAGGACCAAGAGCAATCGCTCTTGCT CCTCCAGAAGAATCAGTGGGGAGTGAGGAGGGGGCTAGGCCCCATTCTCACCCCCGACCACCTTCACCAACTCCCTTTCCGTCCCGCGCC TCCTTCTCCCCATCCGGGGGACTCAGCTGCAGGTTCTGTCAGCAGAGAGACCCTTGCTTGACTGTGGTCTGAAGCTGCCTGGGTTTGAAG GGGCCAGCGGGTCCAATCAGTGGGCTGACCGGATAGGCTACTCGGTCTCATTCATTCATCTAGAACCGCATCACAGAAATCTCCTAGTGC CTAAAAACTGCCTGCTCGCTCTCTCAGAGCCAGGGAGCTGCTGTGTCCATAAGCACAATAATGATTCTTTTCTTGCCTGCTGGAACTCTC TGGTCCCCACTGAGTGACCCTTCCTTTGCTGACCCCTGAGGGCCCAACCCTGGCCCTGTGCCCCTCCCCTCAACTCCAGGACCAGGAGGG GTTCCCTTCCTTCAGCTGCCTCCCCATTGGTGGGAACTCCACCCCCTTCCAGCTGACTGCCCGCCCATAAGGACCCTGGGCCTGTCCTTT CAGCGGGCTGTGCTCCTTCCCTGGCCCTGAGGATTTCACCCTTGAGTTTTCTGGGGTTTTGGCTGTAGCCTTCGCAGAGGGGAGTAGCAA TGGGGTGCTGGCCCTCCCAGACACCCGATCATCTCCGCACTCCCTCCAGGCCTCTAGACCTGACCATGACTGCCACTCAGGCTGCCTTCT CCACCCCTGCTCTGCTCCCAGGAGGCACCTGCGGTGGCCAGAGAGCCAGGGTGGGGAGGGCCACTGTGATGTGCGGGGTCTCGGGCTCAA CATTCGCATCCTGCAGGGCTCCACCTGTTCCCACATGCACCTCCGGCAGGACCTAGACAGAAGTTTCTAGAGAGCAGCTTTTCAGCCCCC AGACAAGGAGGATGAGAGGTGGTTGTCCTGCATCCTCTCCGCTCATCCTTCCTTCCCCATCTCTGTCTACCTGCTCAGTTCAGAGATCAC TCCTACTGCCTGTGTCCCCTTCCCCCACATCCTCCCTGCAACTTTATTCCTCCTAGCTGATCCTTCAGATCCGTGCCTCCTCTGGATCAA AGGGACAAAGACCTATTAGCAAAAGCAAACAAAGGTCCTCCAGGCGACTGGCCTAGGGGCTAACTGGGCAGGTCCCCACAGCATCATCCC TTTGTGCAGGCACTGGGGTACCTGGTAGACCATGGTCCTCAGCTCTGTTGGGGGACCGCCACTGCCCGCCCACCTCAGCCTCTTCCCCGC CTCCAGCCTGGGGGTTGGCATGGTGTGACGGCCTCCTGGGGAGGTGACAGTGAATTCAGCAGCATCCGCTCCCCCAAGACCAGAGAGCCT GGTGGGGGAAAGAAGGGGTTCCCTCATTCTCAGGGCCAGGGCACCCGCTGGGTTGGGGCTGGGGGAATCAACTCCAGGCTATTGGGTGAA GGTGTGATCCTAAAAACAGTCAGATCCAACAGCAGTGCCCTTATAAATGGGGTTTTACCTGCCCTCAGTTCTGCACTCATGGCCCTTTAA AAAGGCGAGTGTAGAAGGAGAATTTATTGGTGTCAGCCCTGGAGATTTTTAATCTAACCAAGTCCACAAACCACAGAGAAAGCAATGGAC TGTGTCCTTTCACTGATTTCAAGAGTTCCAAAGCTCTCATCTCCTTCTCCCCTCTGCAGGGTGTGCCTCCCAACAGGAACAGGAAACCAT CACCCTGGATCTTAGGGGGATGGAGGCTGGGGGTTGTGAAAGCCACTGTCAGACCCCACACTGGGGATGCATTCCTGGAGTCGTGCGGCT GGAAGGCCAGGGACTACCCTCTCTGCTTTCCTCCCAACAGACACATAAACCTTCTTAAGGGCTGGTCCCCAGGGGTTTATAAGAGTTTGT TCCAGAAGGTGAGGCTAAGAGGGTTGGAAAGGAAGAAGTGAGTCTGAATAGAGCAGGTGGCTCCCAGCTGGGCCCCTGAGCCCAGCACCT TTGAATCGTCTAATCTGTGGCCATCCCTTGGAAGGCAGGATGCTGGTGGTGAGGGGAAAGGACCTGAGTGGCTGAGAATGCCCTTCCCAG GTGTCTACATGCAGGTATACACCAAACCAGAAAGCTGATCCCATCTCCAGTGTCAAAGCTTCTCAGCACCAAGTTCTCCAGCCCCCAGGG TGACACTTTTCCCCAGGGGTCCTCCCCAAGCCCTGTCTCTGACAGGGTTTCTGTCTCTCTCAGGGGTTGTTGATGAGTTGATTCCAAGAC ATTTCTCATCCCAGCCTTACCACTGTCTGGCTGAAAGGCTCTGATGTCAGTTGGGTTGGAAAATTCTACTGCAATGCTTACTTCTTTTCA AGGATTTCTTCTGCTTCACCTTTGGGTCTAGAAGCAAGGAATGAAGGGAGGGAGAGAGGGAGGGAGGGAGGGGAGGAGGGAAGAAAAAAG AAGTAGAGATAGGTCTACAGACTTGCTCCAATTCAGTCCCACATTTCAAAATCCAGAAAACTATGTCATAGCTGGGACAGAGAGGTATCC CATTTATTCAGCTGTCCCATCCATCTTCATGGAACAAGCAAAGCCACATCAATAGGCAAGTTCACGTAGCAGATAAAAGAGGCTTCTGGG GCTGGAACCTAGATGCCATGATTTCTAGCCCAACCAGGCTGGTGGCCTCTACCATACATAGAAGTACCATCCACCCTTACAGTAAAAGCC TCCCTCCTGCTCACAAAGGAAGCCTAAAGCCCAAGATTTCCCTCTCCTTGTTTTATTCATTTTTGCACATCTCTGTTGCTCTAACAGAAA TGAACTGGAATCTGCACAGGTTCTCTCCTGCCCTGAAAGTTCTGCCTGGTTTCCTTGGCCTCTGATGGCATTGAAGCTTTCACAATCCCT CCTGCATCTCCACCTTCCCTGTCTTGCTCCAGGCTCCTGGCTCCATGCCTTCCTGTGTCAAAAAGGCTTTGCCAAGAATTACTTCACCTC CTAACCAGGCTTCTGCCCTCAGGGCTCCCCCAGTGTCTTGGGAGTGTCTTGGGCCACACGACTGCCTCTTAGAAAGTTCCAACCTTGCCC CCAATTCAAATTTCTCCTCCCCTCTTTCCACTCTCCCTCCCAGAAACTCCTGATTTCCAGAAAACCTCAGATTTCCAGGCCAGGTCACTC ATTCCTTCCTCTCATCTCCCTCTTCCTCCATCTACCTTCCTCCATTCACCTTCCTCCATTCCTAATTTCTTTTCCCTGGTCTTGCTATAA TCTCCAGCTCTAAAAATCAGAGCTCTCAATGAAAACAATGGAAGAATAAGACATTCTTTCGGTCTTCTGTTTGCCTCACTGGTGTATCCT TCATCTCCTGCCCCTGTGAGTTGATACCCCAGTGCACGGAGCCAAGGGCTTTTCCCCTCTGAGCTCTGGGAGGGAAGGGAATGGAGCTCT GGGTTTGAGATGTCATGGCCTGTGATAGTCAGTTTGGTTCCTGCCACTAGCAAGTCCCCTGAAGCTCCCAACCCAGCCTGATGTTAGCCC AGAAGCTCCTGCTCTGGCCAAAGACTCCTATCCTTGAGGGCTCTCAGCCACTGCTCCAACACACTTGCCCCCTTCCTGCTTGTGTATGTC ACTTATCCTCCTTTGTCCACAAAGACTTGAGGGCCTCCTGAGTCTCCAAGCATGGAGGAATATCCATGCCAACATCCCTGCCATCAAACT CAATCCATTTTCTTCAGAGATACCTTGTCTGTCACCAGCCTCCAACTTCATATTCCTTCCACAGGCAACTGTGCACTTGACCCAAGGTAA AATGAAAGGGCTGCCAATCACTCGGACTCCAGAAGGTGCCTGCCCTGAGAAGAGCTGGCATGTTACCTCCCACATACATTTCCTGTCATC CTGTCCGAATCTGGGAAATTTTGCTCTGGAGTATTTTCAAGAAAGCGCATTGTGTTTTAATGAAGTATTTTTCAGGGTTCCAATGTTATT TTTTATAAATGCAGCATTTTAATGGCAGATTCAATATGAAGGACATGTCTTCCTGGGCTCTATATTTGATTTTGGAAGGCAGCATACTCT AGGAGAAAAAAAGCATAGGGCTGAGGCTCTGAAGACACAGCTTCCAGCCCTGGCTTTGTCTCCGAGGGGGAGTCATGTTCCCCACTCAGT GCCTCAGTTTCCCCATCTGTAAAATGAGGGGCTTTGACTAGATGAGCTCTGAAGTTTCATCCAGCTCTTACACTGTAGGGCTTTCATTCC CTGCCAGCACCTGCTCTCCCCGTTCCTCCCCACCTCCACTGAGCTGCACACATCCCACAATGCCTGCCCCACAGCGATGTCCTCAGATGT CCTGGACAGCCACCGCACTCCTCACTAGAGCCTGGGGTGGGCCTGATGGGCTCGGCCACCCAGGGATGCCCTCGTACCTGAAGTTTAAGG GCCTAACCATTCAATAGGTCACCAACTGTGTGCCATGGAAGCCCTCTTGTAAAGACACACCTAAACCATCCTAAGTGACTGTGGAATTCT GGGGAATTCTGAGTTTGGAGTTTCCATTTGGATACGGTCCTTATAGCTGGAGGGAGGCGGTTCCAATTTCAGAGAGGGAGCTGGCTGGAG AGAAAGGTCTGGAGGTTGGCCCATAAGGGCATGAAGTTTGTACTTGAGGGCAGCTGGGAAATTCATTTCAAGCTGCAGAGGAACGTGTTC ACAGGCTGTTGTGTGGCAATGAATGTCATGATAACCCACTCTGGAATATGTGTCCTGAAGACCAAGTCTGGACACTGAGGCTCCATTCCA ACTGGAGGAGGAGGCATCTCCATCTGGGCTGCTAGGAAGGGGCACTCATCCCATCCTAGTACCTTTGTAGCCCTTCGTCATGACACTACC GTCCTCCCGGTGAAGGCTTGTGAAGCAAGAATGGAGAGTCCAAGTTTGTGATATTCAAACCCATCTTGTAAATCAGCAAACACATTAACC TTCCATCAGTCAGAGAAATAATGTTGTGGCTGTGTGTTTCCTTAATGCTCTCCCTCCTGAGGGAGGAGAAGACCCTGCTCAACTTTGCTG CCCACCCTGCAGTGACCCCTGAATGCCACACCATGGGAGGACTCATTCATTGGCTTTGTAGTGGCAAATATTCCTCTAGTTCTATAACTC AACTAGACATTTTGTAGTAAAGAATTCTTGAAATTCTCTAATAAAAAGCAATTCTTACTGTAATATTTTTAGTTTGGGGACACAATTTCC TAAGGGGGGATTAATGAACATTTTTATGCATTAGCCCAATTTATGAATTCCATGTTTATTATATGGTAGTACTGATGAAAAGTACCTTTC TATCTGTATCTTTGCAGTTTCTTCGTTACTCATATGTAAGCCTCATGGTAAGCAGTGCTCTAGTAACTGCTTCTCTGTACAAATCTCATC GTTCTACTTACCTGTCAAAGCACATTCTACATGTACTGTAAACAGATACACTTTAGTAAGATTTAGTCTTAAGGATTTTTCCACTTTTGT >In-frame_NLGN4Y_ENST00000297967_chrY_16835149_+_SHISA6_ENST00000409168_chr17_11459057_+_7247nt TTTTCGAAAGACTTATCTTTCTGCAGGCTCGCCTCTGAGCTTTGTCTCCTTGGAGCCACCTCACTTAGACAGCTTCGGATGTGGATGCAG ATTTGAACCATGTTGCGTCCCCAGGGACTGCTATGGCTCCCTTTGTTGTTCACCTCTGTCTGTGTCATGTTAAACTCCAATGTTCTTCTG TGGATAACTGCTCTTGCCATCAAGTTCACCCTCATTGACAGCCAAGCACAGTATCCAGTTGTCAACACAAATTATGGTAAAATCCAGGGC CTAAGAACACCATTACCCAGTGAGATCTTGGGTCCAGTGGAGCAGTACTTAGGGGTCCCCTATGCCTCACCCCCAACTGGAGAGAGGCGG TTTCAGCCACCAGAATCCCCATCCTCCTGGACTGGCATCCGAAATGCTACTCAGTTTTCTGCTGTGTGCCCCCAGCACCTGGATGAAAGA TTCTTATTGCATGACATGCTGCCCATCTGGTTTACCACCAGTTTGGATACTTTGATGACCTATGTTCAAGATCAAAATGAAGACTGCCTT TACTTAAACATCTATGTGCCCATGGAAGATGGAACCAACATAAAGAGAAATGCAGACGATATAACCAGTAATGACCATGGTGAAGATAAA GATATTCATGAACAGAACAGTAAGAAGCCTGTTATGGTCTATATCCATGGGGGATCTTACATGGAGGGAACCGGTAACATGATTGATGGC AGCATTTTGGCCAGCTATGGGAACGTCATCGTTATCACCATTAACTACCGTCTGGGAATACTAGAGAAGCCACGGATGAACAACATCCTG ACATCAGCCACCGAGCCCTATGACCTCTCCTTCTCCCGCTCGTTCCAGAACTTGGCCCACCTGCCCCCATCCTACGAGTCTGCAGTAAAG ACCAACCCCAGCAAGTATTCATCTCTGAAGAGGCTAACCGACAAGGAGGCTGACGAGTATTACATGAGACGGCGGCACCTGCCCGACCTG GCTGCCCGCGGCACCCTCCCCCTCAATGTCATCCAGATGTCCCAACAGAAGCCGTTGCCAAGGGAACGACCCCGCCGGCCCATCCGGGCC ATGTCCCAGGACAGGGTCCTGTCCCCGGATCGGGGCCTGCCAGATGAGTTCAGCATGCCCTACGACCGCATCCTGTCCGACGAGCAGCTG CTCTCCACGGAGCGCCTGCACTCCCAGGACCCGCTGCTGTCCCCGGAGCGGACGGCCTTTCCCGAGCAGTCGCTGTCCAGGGCCATCTCG CACACGGACGTCTTTGTGTCCACACCCGTGCTGGACCGCTACCGCATGAGCAAGATGCACTCTCATCCCAGTGCCTCCAATAACTCATAC GCCACCCTGGGCCAGAGCCAGACGGCAGCCAAGCGTCATGCCTTTGCCTCACGCAGACACAACACGGTGGAGCAGCTGCACTACATCCCG GGCCACCACACCTGCTACACAGCCAGCAAGACCGAAGTGACCGTGTGACCGGCGGGGCAGGGCCGGGGCTGCTGGGCGTGGCAGAGCAGA GCGGGGGCCGGGAGGGGCCAGGAGCAGAGCTTCTAGCCTTGCCACTCTCCCTTCCCTTGTCCCCTCTGTAGGAAGTGGGGGTGGGCCACC TTTGCCCAAAAAGCCATACCCCCGGGGACACAGCCCCGATGGCCTGGTCCAATACACTTAGACCCAGGACCAAGAGCAATCGCTCTTGCT CCTCCAGAAGAATCAGTGGGGAGTGAGGAGGGGGCTAGGCCCCATTCTCACCCCCGACCACCTTCACCAACTCCCTTTCCGTCCCGCGCC TCCTTCTCCCCATCCGGGGGACTCAGCTGCAGGTTCTGTCAGCAGAGAGACCCTTGCTTGACTGTGGTCTGAAGCTGCCTGGGTTTGAAG GGGCCAGCGGGTCCAATCAGTGGGCTGACCGGATAGGCTACTCGGTCTCATTCATTCATCTAGAACCGCATCACAGAAATCTCCTAGTGC CTAAAAACTGCCTGCTCGCTCTCTCAGAGCCAGGGAGCTGCTGTGTCCATAAGCACAATAATGATTCTTTTCTTGCCTGCTGGAACTCTC TGGTCCCCACTGAGTGACCCTTCCTTTGCTGACCCCTGAGGGCCCAACCCTGGCCCTGTGCCCCTCCCCTCAACTCCAGGACCAGGAGGG GTTCCCTTCCTTCAGCTGCCTCCCCATTGGTGGGAACTCCACCCCCTTCCAGCTGACTGCCCGCCCATAAGGACCCTGGGCCTGTCCTTT CAGCGGGCTGTGCTCCTTCCCTGGCCCTGAGGATTTCACCCTTGAGTTTTCTGGGGTTTTGGCTGTAGCCTTCGCAGAGGGGAGTAGCAA TGGGGTGCTGGCCCTCCCAGACACCCGATCATCTCCGCACTCCCTCCAGGCCTCTAGACCTGACCATGACTGCCACTCAGGCTGCCTTCT CCACCCCTGCTCTGCTCCCAGGAGGCACCTGCGGTGGCCAGAGAGCCAGGGTGGGGAGGGCCACTGTGATGTGCGGGGTCTCGGGCTCAA CATTCGCATCCTGCAGGGCTCCACCTGTTCCCACATGCACCTCCGGCAGGACCTAGACAGAAGTTTCTAGAGAGCAGCTTTTCAGCCCCC AGACAAGGAGGATGAGAGGTGGTTGTCCTGCATCCTCTCCGCTCATCCTTCCTTCCCCATCTCTGTCTACCTGCTCAGTTCAGAGATCAC TCCTACTGCCTGTGTCCCCTTCCCCCACATCCTCCCTGCAACTTTATTCCTCCTAGCTGATCCTTCAGATCCGTGCCTCCTCTGGATCAA AGGGACAAAGACCTATTAGCAAAAGCAAACAAAGGTCCTCCAGGCGACTGGCCTAGGGGCTAACTGGGCAGGTCCCCACAGCATCATCCC TTTGTGCAGGCACTGGGGTACCTGGTAGACCATGGTCCTCAGCTCTGTTGGGGGACCGCCACTGCCCGCCCACCTCAGCCTCTTCCCCGC CTCCAGCCTGGGGGTTGGCATGGTGTGACGGCCTCCTGGGGAGGTGACAGTGAATTCAGCAGCATCCGCTCCCCCAAGACCAGAGAGCCT GGTGGGGGAAAGAAGGGGTTCCCTCATTCTCAGGGCCAGGGCACCCGCTGGGTTGGGGCTGGGGGAATCAACTCCAGGCTATTGGGTGAA GGTGTGATCCTAAAAACAGTCAGATCCAACAGCAGTGCCCTTATAAATGGGGTTTTACCTGCCCTCAGTTCTGCACTCATGGCCCTTTAA AAAGGCGAGTGTAGAAGGAGAATTTATTGGTGTCAGCCCTGGAGATTTTTAATCTAACCAAGTCCACAAACCACAGAGAAAGCAATGGAC TGTGTCCTTTCACTGATTTCAAGAGTTCCAAAGCTCTCATCTCCTTCTCCCCTCTGCAGGGTGTGCCTCCCAACAGGAACAGGAAACCAT CACCCTGGATCTTAGGGGGATGGAGGCTGGGGGTTGTGAAAGCCACTGTCAGACCCCACACTGGGGATGCATTCCTGGAGTCGTGCGGCT GGAAGGCCAGGGACTACCCTCTCTGCTTTCCTCCCAACAGACACATAAACCTTCTTAAGGGCTGGTCCCCAGGGGTTTATAAGAGTTTGT TCCAGAAGGTGAGGCTAAGAGGGTTGGAAAGGAAGAAGTGAGTCTGAATAGAGCAGGTGGCTCCCAGCTGGGCCCCTGAGCCCAGCACCT TTGAATCGTCTAATCTGTGGCCATCCCTTGGAAGGCAGGATGCTGGTGGTGAGGGGAAAGGACCTGAGTGGCTGAGAATGCCCTTCCCAG GTGTCTACATGCAGGTATACACCAAACCAGAAAGCTGATCCCATCTCCAGTGTCAAAGCTTCTCAGCACCAAGTTCTCCAGCCCCCAGGG TGACACTTTTCCCCAGGGGTCCTCCCCAAGCCCTGTCTCTGACAGGGTTTCTGTCTCTCTCAGGGGTTGTTGATGAGTTGATTCCAAGAC ATTTCTCATCCCAGCCTTACCACTGTCTGGCTGAAAGGCTCTGATGTCAGTTGGGTTGGAAAATTCTACTGCAATGCTTACTTCTTTTCA AGGATTTCTTCTGCTTCACCTTTGGGTCTAGAAGCAAGGAATGAAGGGAGGGAGAGAGGGAGGGAGGGAGGGGAGGAGGGAAGAAAAAAG AAGTAGAGATAGGTCTACAGACTTGCTCCAATTCAGTCCCACATTTCAAAATCCAGAAAACTATGTCATAGCTGGGACAGAGAGGTATCC CATTTATTCAGCTGTCCCATCCATCTTCATGGAACAAGCAAAGCCACATCAATAGGCAAGTTCACGTAGCAGATAAAAGAGGCTTCTGGG GCTGGAACCTAGATGCCATGATTTCTAGCCCAACCAGGCTGGTGGCCTCTACCATACATAGAAGTACCATCCACCCTTACAGTAAAAGCC TCCCTCCTGCTCACAAAGGAAGCCTAAAGCCCAAGATTTCCCTCTCCTTGTTTTATTCATTTTTGCACATCTCTGTTGCTCTAACAGAAA TGAACTGGAATCTGCACAGGTTCTCTCCTGCCCTGAAAGTTCTGCCTGGTTTCCTTGGCCTCTGATGGCATTGAAGCTTTCACAATCCCT CCTGCATCTCCACCTTCCCTGTCTTGCTCCAGGCTCCTGGCTCCATGCCTTCCTGTGTCAAAAAGGCTTTGCCAAGAATTACTTCACCTC CTAACCAGGCTTCTGCCCTCAGGGCTCCCCCAGTGTCTTGGGAGTGTCTTGGGCCACACGACTGCCTCTTAGAAAGTTCCAACCTTGCCC CCAATTCAAATTTCTCCTCCCCTCTTTCCACTCTCCCTCCCAGAAACTCCTGATTTCCAGAAAACCTCAGATTTCCAGGCCAGGTCACTC ATTCCTTCCTCTCATCTCCCTCTTCCTCCATCTACCTTCCTCCATTCACCTTCCTCCATTCCTAATTTCTTTTCCCTGGTCTTGCTATAA TCTCCAGCTCTAAAAATCAGAGCTCTCAATGAAAACAATGGAAGAATAAGACATTCTTTCGGTCTTCTGTTTGCCTCACTGGTGTATCCT TCATCTCCTGCCCCTGTGAGTTGATACCCCAGTGCACGGAGCCAAGGGCTTTTCCCCTCTGAGCTCTGGGAGGGAAGGGAATGGAGCTCT GGGTTTGAGATGTCATGGCCTGTGATAGTCAGTTTGGTTCCTGCCACTAGCAAGTCCCCTGAAGCTCCCAACCCAGCCTGATGTTAGCCC AGAAGCTCCTGCTCTGGCCAAAGACTCCTATCCTTGAGGGCTCTCAGCCACTGCTCCAACACACTTGCCCCCTTCCTGCTTGTGTATGTC ACTTATCCTCCTTTGTCCACAAAGACTTGAGGGCCTCCTGAGTCTCCAAGCATGGAGGAATATCCATGCCAACATCCCTGCCATCAAACT CAATCCATTTTCTTCAGAGATACCTTGTCTGTCACCAGCCTCCAACTTCATATTCCTTCCACAGGCAACTGTGCACTTGACCCAAGGTAA AATGAAAGGGCTGCCAATCACTCGGACTCCAGAAGGTGCCTGCCCTGAGAAGAGCTGGCATGTTACCTCCCACATACATTTCCTGTCATC CTGTCCGAATCTGGGAAATTTTGCTCTGGAGTATTTTCAAGAAAGCGCATTGTGTTTTAATGAAGTATTTTTCAGGGTTCCAATGTTATT TTTTATAAATGCAGCATTTTAATGGCAGATTCAATATGAAGGACATGTCTTCCTGGGCTCTATATTTGATTTTGGAAGGCAGCATACTCT AGGAGAAAAAAAGCATAGGGCTGAGGCTCTGAAGACACAGCTTCCAGCCCTGGCTTTGTCTCCGAGGGGGAGTCATGTTCCCCACTCAGT GCCTCAGTTTCCCCATCTGTAAAATGAGGGGCTTTGACTAGATGAGCTCTGAAGTTTCATCCAGCTCTTACACTGTAGGGCTTTCATTCC CTGCCAGCACCTGCTCTCCCCGTTCCTCCCCACCTCCACTGAGCTGCACACATCCCACAATGCCTGCCCCACAGCGATGTCCTCAGATGT CCTGGACAGCCACCGCACTCCTCACTAGAGCCTGGGGTGGGCCTGATGGGCTCGGCCACCCAGGGATGCCCTCGTACCTGAAGTTTAAGG GCCTAACCATTCAATAGGTCACCAACTGTGTGCCATGGAAGCCCTCTTGTAAAGACACACCTAAACCATCCTAAGTGACTGTGGAATTCT GGGGAATTCTGAGTTTGGAGTTTCCATTTGGATACGGTCCTTATAGCTGGAGGGAGGCGGTTCCAATTTCAGAGAGGGAGCTGGCTGGAG AGAAAGGTCTGGAGGTTGGCCCATAAGGGCATGAAGTTTGTACTTGAGGGCAGCTGGGAAATTCATTTCAAGCTGCAGAGGAACGTGTTC ACAGGCTGTTGTGTGGCAATGAATGTCATGATAACCCACTCTGGAATATGTGTCCTGAAGACCAAGTCTGGACACTGAGGCTCCATTCCA ACTGGAGGAGGAGGCATCTCCATCTGGGCTGCTAGGAAGGGGCACTCATCCCATCCTAGTACCTTTGTAGCCCTTCGTCATGACACTACC GTCCTCCCGGTGAAGGCTTGTGAAGCAAGAATGGAGAGTCCAAGTTTGTGATATTCAAACCCATCTTGTAAATCAGCAAACACATTAACC TTCCATCAGTCAGAGAAATAATGTTGTGGCTGTGTGTTTCCTTAATGCTCTCCCTCCTGAGGGAGGAGAAGACCCTGCTCAACTTTGCTG CCCACCCTGCAGTGACCCCTGAATGCCACACCATGGGAGGACTCATTCATTGGCTTTGTAGTGGCAAATATTCCTCTAGTTCTATAACTC AACTAGACATTTTGTAGTAAAGAATTCTTGAAATTCTCTAATAAAAAGCAATTCTTACTGTAATATTTTTAGTTTGGGGACACAATTTCC TAAGGGGGGATTAATGAACATTTTTATGCATTAGCCCAATTTATGAATTCCATGTTTATTATATGGTAGTACTGATGAAAAGTACCTTTC TATCTGTATCTTTGCAGTTTCTTCGTTACTCATATGTAAGCCTCATGGTAAGCAGTGCTCTAGTAACTGCTTCTCTGTACAAATCTCATC GTTCTACTTACCTGTCAAAGCACATTCTACATGTACTGTAAACAGATACACTTTAGTAAGATTTAGTCTTAAGGATTTTTCCACTTTTGT |
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FusionGenePPI for NLGN4Y_SHISA6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NLGN4Y | NLGN3, PRIM1, PRIM2 | SHISA6 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NLGN4Y_SHISA6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NLGN4Y_SHISA6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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