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Fusion gene ID: 2414 |
FusionGeneSummary for ARHGAP24_NOA1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARHGAP24_NOA1 | Fusion gene ID: 2414 | Hgene | Tgene | Gene symbol | ARHGAP24 | NOA1 | Gene ID | 83478 | 84273 |
| Gene name | Rho GTPase activating protein 24 | nitric oxide associated 1 | |
| Synonyms | FILGAP|RC-GAP72|RCGAP72|p73|p73RhoGAP | C4orf14|MTG3|hAtNOS1|hNOA1|mAtNOS1 | |
| Cytomap | 4q21.23-q21.3 | 4q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rho GTPase-activating protein 24RAC1- and CDC42-specific GTPase-activating protein of 72 kDafilamin-A-associated RhoGAPrhoGAP of 73 kDasarcoma antigen NY-SAR-88 | nitric oxide-associated protein 1mitochondrial GTPase 3 homolognitric oxide synthase, mitochondrial (putative)putative ortholog of Arabidopsis mitochondrial nitric oxide synthase | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q8N264 | Q8NC60 | |
| Ensembl transtripts involved in fusion gene | ENST00000395184, ENST00000503995, ENST00000506421, ENST00000395183, ENST00000264343, | ENST00000264230, | |
| Fusion gene scores | * DoF score | 5 X 6 X 4=120 | 2 X 1 X 2=4 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: ARHGAP24 [Title/Abstract] AND NOA1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E2-A1IO-01A | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000395184 | ENST00000264230 | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
| In-frame | ENST00000503995 | ENST00000264230 | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
| 3UTR-3CDS | ENST00000506421 | ENST00000264230 | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
| intron-3CDS | ENST00000395183 | ENST00000264230 | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
| intron-3CDS | ENST00000264343 | ENST00000264230 | ARHGAP24 | chr4 | 86643125 | + | NOA1 | chr4 | 57840188 | - |
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FusionProtFeatures for ARHGAP24_NOA1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARHGAP24 | NOA1 |
| Rho GTPase-activating protein involved in cell polarity,cell morphology and cytoskeletal organization. Acts as a GTPaseactivator for the Rac-type GTPase by converting it to an inactiveGDP-bound state. Controls actin remodeling by inactivating Racdownstream of Rho leading to suppress leading edge protrusion andpromotes cell retraction to achieve cellular polarity. Able tosuppress RAC1 and CDC42 activity in vitro. Overexpression inducescell rounding with partial or complete disruption of actin stressfibers and formation of membrane ruffles, lamellipodia, andfilopodia. Isoform 2 is a vascular cell-specific GAP involved inmodulation of angiogenesis. {ECO:0000269|PubMed:15302923,ECO:0000269|PubMed:15611138, ECO:0000269|PubMed:16862148}. | Involved in regulation of mitochondrial proteintranslation and respiration. Plays a role in mitochondria-mediatedcell death. May act as a scaffolding protein or stabilizer ofrespiratory chain supercomplexes. Binds GTP.{ECO:0000269|PubMed:19103604}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000264343 | + | 1 | 7 | 649_729 | -220 | 656 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395183 | + | 1 | 8 | 649_729 | -93 | 654 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395184 | + | 3 | 10 | 649_729 | 89 | 749 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000503995 | + | 3 | 6 | 649_729 | 89 | 247 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000264343 | + | 1 | 7 | 135_329 | -220 | 656 | Domain | Rho-GAP |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000264343 | + | 1 | 7 | 19_125 | -220 | 656 | Domain | PH |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395183 | + | 1 | 8 | 135_329 | -93 | 654 | Domain | Rho-GAP |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395183 | + | 1 | 8 | 19_125 | -93 | 654 | Domain | PH |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395184 | + | 3 | 10 | 135_329 | 89 | 749 | Domain | Rho-GAP |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000395184 | + | 3 | 10 | 19_125 | 89 | 749 | Domain | PH |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000503995 | + | 3 | 6 | 135_329 | 89 | 247 | Domain | Rho-GAP |
| Hgene | >ARHGAP24 | chr4:86643125 | chr4:57840188 | ENST00000503995 | + | 3 | 6 | 19_125 | 89 | 247 | Domain | PH |
| Tgene | NOA1 | chr4:86643125 | chr4:57840188 | ENST00000264230 | - | 0 | 7 | 202_503 | 381 | 699 | Domain | CP-type G |
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FusionGeneSequence for ARHGAP24_NOA1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ARHGAP24_ENST00000395184_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_407aa MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENPGKFLFEVVPG TTLNLLKFPICNPTPYRMFKRHQRLKKDSTQAEEDLSEQEQNQLNVLKKHGYVVGRVGRTFLYSEEQKDNIPFEFDADSLAFDMENDPVM GTHKSTKQVELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIVPRTFVLKPGMVLFLGAIGRIDFLQGNQSAWFTVVASN ILPVHITSLDRADALYQKHAGHTLLQIPMGGKERMAGFPPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTV >In-frame_ARHGAP24_ENST00000503995_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_407aa MEENNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENPGKFLFEVVPG TTLNLLKFPICNPTPYRMFKRHQRLKKDSTQAEEDLSEQEQNQLNVLKKHGYVVGRVGRTFLYSEEQKDNIPFEFDADSLAFDMENDPVM GTHKSTKQVELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIVPRTFVLKPGMVLFLGAIGRIDFLQGNQSAWFTVVASN ILPVHITSLDRADALYQKHAGHTLLQIPMGGKERMAGFPPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ARHGAP24_ENST00000395184_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_1221nt ATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGA GGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTG GGTACTATTTTTCTGCCTGGAAATAAAGTTTCTGAGCATCCCTGCAATGAAGAGAACCCAGGGAAGTTCCTTTTTGAAGTAGTTCCAGGT ACTACATTAAACCTTCTGAAGTTTCCTATTTGCAACCCAACTCCTTACAGAATGTTTAAAAGGCATCAAAGACTTAAAAAAGATTCAACT CAAGCTGAAGAAGATCTTAGTGAGCAAGAACAAAATCAGCTTAATGTCCTCAAAAAGCATGGTTATGTCGTAGGAAGAGTTGGAAGGACA TTCTTGTATTCAGAAGAACAGAAGGATAACATTCCCTTTGAGTTTGATGCTGATTCACTTGCCTTTGACATGGAAAATGACCCTGTTATG GGTACACACAAATCCACCAAACAAGTAGAATTGACTGCACAAGATGTGAAAGATGCCCACTGGTTTTATGACACCCCTGGAATTACAAAA GAAAATTGTATTTTAAATCTTCTAACAGAAAAAGAAGTAAATATTGTTTTGCCAACACAGTCCATTGTTCCAAGAACTTTTGTGCTTAAA CCAGGAATGGTTCTGTTTTTGGGTGCTATAGGCCGCATAGATTTCCTGCAGGGAAATCAGTCAGCTTGGTTTACAGTCGTGGCTTCCAAC ATCCTCCCTGTGCATATCACCTCCTTGGACAGGGCAGACGCTCTGTATCAGAAGCATGCAGGTCATACGTTACTCCAGATTCCAATGGGT GGAAAAGAACGAATGGCAGGATTTCCTCCTCTTGTTGCTGAAGACATTATGTTAAAAGAAGGACTGGGGGCATCTGAAGCAGTGGCCGAC ATCAAGTTTTCCTCTGCAGGTTGGGTTTCAGTAACACCTAATTTTAAGGACAGACTGCATCTCCGAGGCTATACACCTGAAGGAACAGTT TTGACCGTCCGGCCCCCTCTCTTGCCATATATTGTTAACATCAAAGGACAGCGCATCAAGAAAAGTGTGGCCTATAAAACCAAGAAGCCT >In-frame_ARHGAP24_ENST00000503995_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_1221nt ATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGA GGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTG GGTACTATTTTTCTGCCTGGAAATAAAGTTTCTGAGCATCCCTGCAATGAAGAGAACCCAGGGAAGTTCCTTTTTGAAGTAGTTCCAGGT ACTACATTAAACCTTCTGAAGTTTCCTATTTGCAACCCAACTCCTTACAGAATGTTTAAAAGGCATCAAAGACTTAAAAAAGATTCAACT CAAGCTGAAGAAGATCTTAGTGAGCAAGAACAAAATCAGCTTAATGTCCTCAAAAAGCATGGTTATGTCGTAGGAAGAGTTGGAAGGACA TTCTTGTATTCAGAAGAACAGAAGGATAACATTCCCTTTGAGTTTGATGCTGATTCACTTGCCTTTGACATGGAAAATGACCCTGTTATG GGTACACACAAATCCACCAAACAAGTAGAATTGACTGCACAAGATGTGAAAGATGCCCACTGGTTTTATGACACCCCTGGAATTACAAAA GAAAATTGTATTTTAAATCTTCTAACAGAAAAAGAAGTAAATATTGTTTTGCCAACACAGTCCATTGTTCCAAGAACTTTTGTGCTTAAA CCAGGAATGGTTCTGTTTTTGGGTGCTATAGGCCGCATAGATTTCCTGCAGGGAAATCAGTCAGCTTGGTTTACAGTCGTGGCTTCCAAC ATCCTCCCTGTGCATATCACCTCCTTGGACAGGGCAGACGCTCTGTATCAGAAGCATGCAGGTCATACGTTACTCCAGATTCCAATGGGT GGAAAAGAACGAATGGCAGGATTTCCTCCTCTTGTTGCTGAAGACATTATGTTAAAAGAAGGACTGGGGGCATCTGAAGCAGTGGCCGAC ATCAAGTTTTCCTCTGCAGGTTGGGTTTCAGTAACACCTAATTTTAAGGACAGACTGCATCTCCGAGGCTATACACCTGAAGGAACAGTT TTGACCGTCCGGCCCCCTCTCTTGCCATATATTGTTAACATCAAAGGACAGCGCATCAAGAAAAGTGTGGCCTATAAAACCAAGAAGCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ARHGAP24_ENST00000395184_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_1767nt TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA TGAAACCAAGCCCTTGGGTACTATTTTTCTGCCTGGAAATAAAGTTTCTGAGCATCCCTGCAATGAAGAGAACCCAGGGAAGTTCCTTTT TGAAGTAGTTCCAGGTACTACATTAAACCTTCTGAAGTTTCCTATTTGCAACCCAACTCCTTACAGAATGTTTAAAAGGCATCAAAGACT TAAAAAAGATTCAACTCAAGCTGAAGAAGATCTTAGTGAGCAAGAACAAAATCAGCTTAATGTCCTCAAAAAGCATGGTTATGTCGTAGG AAGAGTTGGAAGGACATTCTTGTATTCAGAAGAACAGAAGGATAACATTCCCTTTGAGTTTGATGCTGATTCACTTGCCTTTGACATGGA AAATGACCCTGTTATGGGTACACACAAATCCACCAAACAAGTAGAATTGACTGCACAAGATGTGAAAGATGCCCACTGGTTTTATGACAC CCCTGGAATTACAAAAGAAAATTGTATTTTAAATCTTCTAACAGAAAAAGAAGTAAATATTGTTTTGCCAACACAGTCCATTGTTCCAAG AACTTTTGTGCTTAAACCAGGAATGGTTCTGTTTTTGGGTGCTATAGGCCGCATAGATTTCCTGCAGGGAAATCAGTCAGCTTGGTTTAC AGTCGTGGCTTCCAACATCCTCCCTGTGCATATCACCTCCTTGGACAGGGCAGACGCTCTGTATCAGAAGCATGCAGGTCATACGTTACT CCAGATTCCAATGGGTGGAAAAGAACGAATGGCAGGATTTCCTCCTCTTGTTGCTGAAGACATTATGTTAAAAGAAGGACTGGGGGCATC TGAAGCAGTGGCCGACATCAAGTTTTCCTCTGCAGGTTGGGTTTCAGTAACACCTAATTTTAAGGACAGACTGCATCTCCGAGGCTATAC ACCTGAAGGAACAGTTTTGACCGTCCGGCCCCCTCTCTTGCCATATATTGTTAACATCAAAGGACAGCGCATCAAGAAAAGTGTGGCCTA TAAAACCAAGAAGCCTCCTTCCCTTATGTACAACGTGAGGAAGAAGAAAGGAAAGATAAATGTATGAGACCGACCTTGTTCACTCCAGAT >In-frame_ARHGAP24_ENST00000503995_chr4_86643125_+_NOA1_ENST00000264230_chr4_57840188_-_1643nt GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGGGTACTATTTTTCTGCCT GGAAATAAAGTTTCTGAGCATCCCTGCAATGAAGAGAACCCAGGGAAGTTCCTTTTTGAAGTAGTTCCAGGTACTACATTAAACCTTCTG AAGTTTCCTATTTGCAACCCAACTCCTTACAGAATGTTTAAAAGGCATCAAAGACTTAAAAAAGATTCAACTCAAGCTGAAGAAGATCTT AGTGAGCAAGAACAAAATCAGCTTAATGTCCTCAAAAAGCATGGTTATGTCGTAGGAAGAGTTGGAAGGACATTCTTGTATTCAGAAGAA CAGAAGGATAACATTCCCTTTGAGTTTGATGCTGATTCACTTGCCTTTGACATGGAAAATGACCCTGTTATGGGTACACACAAATCCACC AAACAAGTAGAATTGACTGCACAAGATGTGAAAGATGCCCACTGGTTTTATGACACCCCTGGAATTACAAAAGAAAATTGTATTTTAAAT CTTCTAACAGAAAAAGAAGTAAATATTGTTTTGCCAACACAGTCCATTGTTCCAAGAACTTTTGTGCTTAAACCAGGAATGGTTCTGTTT TTGGGTGCTATAGGCCGCATAGATTTCCTGCAGGGAAATCAGTCAGCTTGGTTTACAGTCGTGGCTTCCAACATCCTCCCTGTGCATATC ACCTCCTTGGACAGGGCAGACGCTCTGTATCAGAAGCATGCAGGTCATACGTTACTCCAGATTCCAATGGGTGGAAAAGAACGAATGGCA GGATTTCCTCCTCTTGTTGCTGAAGACATTATGTTAAAAGAAGGACTGGGGGCATCTGAAGCAGTGGCCGACATCAAGTTTTCCTCTGCA GGTTGGGTTTCAGTAACACCTAATTTTAAGGACAGACTGCATCTCCGAGGCTATACACCTGAAGGAACAGTTTTGACCGTCCGGCCCCCT CTCTTGCCATATATTGTTAACATCAAAGGACAGCGCATCAAGAAAAGTGTGGCCTATAAAACCAAGAAGCCTCCTTCCCTTATGTACAAC GTGAGGAAGAAGAAAGGAAAGATAAATGTATGAGACCGACCTTGTTCACTCCAGATATTAACTGTATTGAACACAACAAAATACATTGAA |
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FusionGenePPI for ARHGAP24_NOA1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ARHGAP24 | APP | NOA1 | ARF1, COL9A2, HSPA8, MPP3, ICT1, GRB10, BOK, LIN28A, ZNF346, TRA2A, TRMT10B, MRPS11, MRPS27, MRPS34, AURKAIP1, FGF8, MRPS15, KLHL22, CCDC59 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ARHGAP24_NOA1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ARHGAP24_NOA1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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