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Fusion gene ID: 24108 |
FusionGeneSummary for NF1_SLC46A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NF1_SLC46A1 | Fusion gene ID: 24108 | Hgene | Tgene | Gene symbol | NF1 | SLC46A1 | Gene ID | 4763 | 113235 |
| Gene name | neurofibromin 1 | solute carrier family 46 member 1 | |
| Synonyms | NFNS|VRNF|WSS | G21|HCP1|PCFT | |
| Cytomap | 17q11.2 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neurofibrominneurofibromatosis 1neurofibromatosis-related protein NF-1truncated neurofibromin 1 | proton-coupled folate transporterheme carrier protein 1solute carrier family 46 (folate transporter), member 1 | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | P21359 | Q96NT5 | |
| Ensembl transtripts involved in fusion gene | ENST00000356175, ENST00000358273, ENST00000431387, ENST00000581113, ENST00000417592, ENST00000444181, | ENST00000321666, ENST00000440501, ENST00000584729, | |
| Fusion gene scores | * DoF score | 35 X 18 X 19=11970 | 1 X 1 X 1=1 |
| # samples | 46 | 1 | |
| ** MAII score | log2(46/11970*10)=-4.70164548088649 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NF1 [Title/Abstract] AND SLC46A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NF1 | GO:0043547 | positive regulation of GTPase activity | 2121371 |
| Tgene | SLC46A1 | GO:0015884 | folic acid transport | 17129779|17475902|19762432 |
| Tgene | SLC46A1 | GO:0051958 | methotrexate transport | 19762432 |
| Tgene | SLC46A1 | GO:1902600 | proton transmembrane transport | 17129779 |
| Tgene | SLC46A1 | GO:1904447 | folate import across plasma membrane | 19762432 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUSC | TCGA-22-5482-01A | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000356175 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| In-frame | ENST00000356175 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| 5CDS-5UTR | ENST00000356175 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| In-frame | ENST00000358273 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| In-frame | ENST00000358273 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| 5CDS-5UTR | ENST00000358273 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| In-frame | ENST00000431387 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| In-frame | ENST00000431387 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| 5CDS-5UTR | ENST00000431387 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000581113 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000581113 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-5UTR | ENST00000581113 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000417592 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000417592 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-5UTR | ENST00000417592 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000444181 | ENST00000321666 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-3CDS | ENST00000444181 | ENST00000440501 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
| intron-5UTR | ENST00000444181 | ENST00000584729 | NF1 | chr17 | 29509683 | + | SLC46A1 | chr17 | 26733015 | - |
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FusionProtFeatures for NF1_SLC46A1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NF1 | SLC46A1 |
| Stimulates the GTPase activity of Ras. NF1 shows greateraffinity for Ras GAP, but lower specific activity. May be aregulator of Ras activity. {ECO:0000269|PubMed:2121371,ECO:0000269|PubMed:8417346}. | Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal hemetransporter which mediates heme uptake from the gut lumen intoduodenal epithelial cells. The iron is then released from heme andmay be transported into the bloodstream. Dietary heme iron is animportant nutritional source of iron. Shows a higher affinity forfolate than heme. {ECO:0000269|PubMed:17129779,ECO:0000269|PubMed:17156779, ECO:0000269|PubMed:17446347,ECO:0000269|PubMed:17475902}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 108_113 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 138_145 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 169_180 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 1_24 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 204_212 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 237_265 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 289_309 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 329_331 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 357_359 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 382_393 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 413_424 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 450_459 | -32 | 460 | Topological domain | Cytoplasmic |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 49_84 | -32 | 460 | Topological domain | Extracellular |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 114_137 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 146_168 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 181_203 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 213_236 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 25_48 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 266_288 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 310_328 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 332_356 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 360_381 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 394_412 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 425_449 | -32 | 460 | Transmembrane | Helical |
| Tgene | >SLC46A1 | chr17:29509683 | chr17:26733015 | ENST00000440501 | - | 0 | 6 | 85_107 | -32 | 460 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000356175 | + | 8 | 57 | 1352_1355 | 296 | 2819 | Compositional bias | Note=Poly-Ser |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000358273 | + | 8 | 58 | 1352_1355 | 296 | 2840 | Compositional bias | Note=Poly-Ser |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000431387 | + | 8 | 15 | 1352_1355 | 296 | 594 | Compositional bias | Note=Poly-Ser |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000356175 | + | 8 | 57 | 1235_1451 | 296 | 2819 | Domain | Ras-GAP |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000356175 | + | 8 | 57 | 1580_1738 | 296 | 2819 | Domain | CRAL-TRIO |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000358273 | + | 8 | 58 | 1235_1451 | 296 | 2840 | Domain | Ras-GAP |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000358273 | + | 8 | 58 | 1580_1738 | 296 | 2840 | Domain | CRAL-TRIO |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000431387 | + | 8 | 15 | 1235_1451 | 296 | 594 | Domain | Ras-GAP |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000431387 | + | 8 | 15 | 1580_1738 | 296 | 594 | Domain | CRAL-TRIO |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000356175 | + | 8 | 57 | 2555_2571 | 296 | 2819 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000358273 | + | 8 | 58 | 2555_2571 | 296 | 2840 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000431387 | + | 8 | 15 | 2555_2571 | 296 | 594 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000356175 | + | 8 | 57 | 1580_1837 | 296 | 2819 | Region | Note=Lipid binding |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000358273 | + | 8 | 58 | 1580_1837 | 296 | 2840 | Region | Note=Lipid binding |
| Hgene | >NF1 | chr17:29509683 | chr17:26733015 | ENST00000431387 | + | 8 | 15 | 1580_1837 | 296 | 594 | Region | Note=Lipid binding |
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FusionGeneSequence for NF1_SLC46A1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_296aa MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTL EKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_888nt ATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACA CATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACT ATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTG GAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTT CTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTC AATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTA CAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTA GCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACT GATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_3037nt AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA ACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGCAGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAG CTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCCCGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGG TAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACC TCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACT GGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCC CGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCGTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCG TGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTC GCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGG CCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCCATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAA AGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGA AACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCA CACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAGCATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCC TGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCA CGCCTCTCATGTTCACAGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAATAGCCTGGCCATGCTGACGGCCTCCGGCTTCAACTCACTCT ACCCAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGCCTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACAT TCTGGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCCCCCGAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGC TGAACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAGCCGGCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCC GCGGCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCACCCCAAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGC AGCTGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCCTATTTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGA >In-frame_NF1_ENST00000356175_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_3124nt AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA ACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGCAGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAG CTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCCCGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGG TAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACC TCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACT GGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCC CGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCGTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCG TGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTC GCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGG CCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCCATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAA AGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGA AACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCA CACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAGCATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCC TGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCA CGCCTCTCATGTTCACAGGATATGGGTTGCTTTTCCTGTCATTAGTCATCACACCTGTCATCCGGGCTAAACTCTCCAAGCTGGTGAGAG AGACAGAGCAGGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAATAGCCTGGCCATGCTGACGGCCTCCGGCATTTTCAACTCACTCTACC CAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGCCTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACATTCT GGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCCCCCGAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGCTGA ACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAGCCGGCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCCGCG GCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCACCCCAAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGCAGC TGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCCTATTTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGAACT >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_3037nt AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA ACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGCAGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAG CTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCCCGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGG TAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACC TCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACT GGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCC CGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCGTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCG TGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTC GCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGG CCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCCATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAA AGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGA AACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCA CACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAGCATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCC TGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCA CGCCTCTCATGTTCACAGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAATAGCCTGGCCATGCTGACGGCCTCCGGCTTCAACTCACTCT ACCCAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGCCTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACAT TCTGGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCCCCCGAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGC TGAACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAGCCGGCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCC GCGGCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCACCCCAAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGC AGCTGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCCTATTTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGA >In-frame_NF1_ENST00000358273_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_3124nt AATCTCTAGCTCGCTCGCGCTCCCTCTCCCCGGGCCGTGGAAAGGATCCCACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGAT GGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCCCCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCC TCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCCCCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTC CACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCCCTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGC CGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGGGTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAA TAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAACAAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTT TGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGAATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTC AGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAGGACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGT TGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAGCATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTAT TTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACCAGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTG ATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAATTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAG CCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCATTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAA AACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTATTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTA AAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAAATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACA ACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGCAGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAG CTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCCCGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGG TAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACC TCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACT GGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCC CGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCGTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCG TGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTC GCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGG CCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCCATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAA AGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGA AACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCA CACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAGCATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCC TGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCA CGCCTCTCATGTTCACAGGATATGGGTTGCTTTTCCTGTCATTAGTCATCACACCTGTCATCCGGGCTAAACTCTCCAAGCTGGTGAGAG AGACAGAGCAGGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAATAGCCTGGCCATGCTGACGGCCTCCGGCATTTTCAACTCACTCTACC CAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGCCTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACATTCT GGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCCCCCGAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGCTGA ACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAGCCGGCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCCGCG GCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCACCCCAAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGCAGC TGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCCTATTTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGAACT >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000321666_chr17_26733015_-_2987nt ACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGATGGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCC CCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCCTCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCC CCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTCCACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCC CTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGCCGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGG GTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAAC AAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGA ATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAG GACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAG CATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACC AGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAA TTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCA TTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTA TTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAA ATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACAACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGC AGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAGCTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCC CGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGGTAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCG CTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACCTCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCG GACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACTGGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCC ACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCCCGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCC GTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCGTGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTG GCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTCGCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCT GGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGGCCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCC ATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAAAGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATT GTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGAAACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCAC TTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCACACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAG CATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCCTGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTC AACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCACGCCTCTCATGTTCACAGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAAT AGCCTGGCCATGCTGACGGCCTCCGGCTTCAACTCACTCTACCCAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCT GGCCTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACATTCTGGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCC CCCGAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGCTGAACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAG CCGGCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCCGCGGCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCAC CCCAAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGCAGCTGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCC TATTTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGAACTGCAACACTCCCATCCCGGAGGACTAGGCGCTCCCCGTGCCTTGCCCC >In-frame_NF1_ENST00000431387_chr17_29509683_+_SLC46A1_ENST00000440501_chr17_26733015_-_3074nt ACTTCCGGTGGGGTGTCATGGCGGCGTCTCGGACTGTGATGGCTGTGGGGAGACGGCGCTAGTGGGGAGAGCGACCAAGAGGCCCCCTCC CCTCCCCGGGTCCCCTTCCCCTATCCCCCTCCCCCCAGCCTCCTTGCCAACGCCCCCTTTCCCTCTCCCCCTCCCGCTCGGCGCTGACCC CCCATCCCCACCCCCGTGGGAACACTGGGAGCCTGCACTCCACAGACCCTCTCCTTGCCTCTTCCCTCACCTCAGCCTCCGCTCCCCGCC CTCTTCCCGGCCCAGGGCGCCGGCCCACCCTTCCCTCCGCCGCCCCCCGGCCGCGGGGAGGACATGGCCGCGCACAGGCCGGTGGAATGG GTCCAGGCCGTGGTCAGCCGCTTCGACGAGCAGCTTCCAATAAAAACAGGACAGCAGAACACACATACCAAAGTCAGTACTGAGCACAAC AAGGAATGTCTAATCAATATTTCCAAATACAAGTTTTCTTTGGTTATAAGCGGCCTCACTACTATTTTAAAGAATGTTAACAATATGAGA ATATTTGGAGAAGCTGCTGAAAAAAATTTATATCTCTCTCAGTTGATTATATTGGATACACTGGAAAAATGTCTTGCTGGGCAACCAAAG GACACAATGAGATTAGATGAAACGATGCTGGTCAAACAGTTGCTGCCAGAAATCTGCCATTTTCTTCACACCTGTCGTGAAGGAAACCAG CATGCAGCTGAACTTCGGAATTCTGCCTCTGGGGTTTTATTTTCTCTCAGCTGCAACAACTTCAATGCAGTCTTTAGTCGCATTTCTACC AGGTTACAGGAATTAACTGTTTGTTCAGAAGACAATGTTGATGTTCATGATATAGAATTGTTACAGTATATCAATGTGGATTGTGCAAAA TTAAAACGACTCCTGAAGGAAACAGCATTTAAATTTAAAGCCCTAAAGAAGGTTGCGCAGTTAGCAGTTATAAATAGCCTGGAAAAGGCA TTTTGGAACTGGGTAGAAAATTATCCAGATGAATTTACAAAACTGTACCAGATCCCACAGACTGATATGGCTGAATGTGCAGAAAAGCTA TTTGACTTGGTGGATGGTTTTGCTGAAAGCACCAAACGTAAAGCAGCAGTTTGGCCACTACAAATCATTCTCCTTATCTTGTGTCCAGAA ATAATCCAGGATATATCCAAAGACGTGGTTGATGAAAACAACATGAATAAGACAGCGCAAGCCCCACGCCACGCGTCGCTGGTCCCAGGC AGCGAGTCGCTCGCGCGCCCCGCCGCCCGCCTGGCGACAGCTCCGCCGCGCACGCACATGGAGGGGAGCGCGAGCCCCCCGGAAAAGCCC CGCGCCCGCCCTGCGGCTGCCGTGCTGTGCCGGGGCCCGGTAGAGCCGCTGGTCTTCCTGGCCAACTTTGCCTTGGTCCTGCAGGGCCCG CTCACCACGCAGTATCTGTGGCACCGCTTCAGCGCCGACCTCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCG GACCCCACCATGCAGGAAGTGGAGACCCTTACCTCCCACTGGACCCTCTACATGAACGTGGGCGGCTTCCTGGTGGGGCTCTTCTCGTCC ACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCCCGCTGCTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCC GTTTTTGTGGTGCAGCTGCAGCTCCACGTCGGCTACTTCGTGCTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTTCTG GCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGTCGCAGCCGCACCTTCCGGATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCT GGGATGCTGGCAAGCCTCCTCGGGGGCCACTGGCTCCGGGCCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTGGCCTTGCTGATAGCC ATGACTCTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAAAGGAGCCAAAGTCCACCCGGCTCTTCACGTTCCGTCACCACCGATCCATT GTCCAGCTCTATGTGGCTCCCGCCCCAGAGAAGTCCAGGAAACATTTAGCCCTCTACTCACTGGCCATCTTCGTGGTGATCACTGTGCAC TTTGGGGCCCAGGACATCTTAACCCTTTATGAACTAAGCACACCCCTCTGCTGGGACTCCAAACTAATCGGCTATGGTTCTGCAGCTCAG CATCTCCCCTACCTCACCAGCCTGCTGGCCCTGAAGCTCCTGCAGTACTGCCTGGCCGATGCCTGGGTAGCTGAGATCGGCCTGGCCTTC AACATCCTGGGGATGGTGGTCTTTGCCTTTGCCACTATCACGCCTCTCATGTTCACAGGATATGGGTTGCTTTTCCTGTCATTAGTCATC ACACCTGTCATCCGGGCTAAACTCTCCAAGCTGGTGAGAGAGACAGAGCAGGGTGCTCTCTTTTCTGCTGTGGCCTGTGTGAATAGCCTG GCCATGCTGACGGCCTCCGGCATTTTCAACTCACTCTACCCAGCCACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGC CTCCTGCTCATCCCGGCTGTTCTGATTGGGCACACATTCTGGCAGTTCCGCCATGAGAACCCCCAGACCCGGGTTGGGGGCCCGCCCCCC GAGGGGCTGCCGGGCTTCAACAGCGGGGTGATGTTGCTGAACCTGGAGGCCATGCGCCAGTCCCCGCTCTACAGCCGCCTGCTGGAGCCG GCGCAGGTGCAGCAGCTGGCCGACAAGTACCACTTCCGCGGCCACCTCGGGGACCAGGACTTCTTCACCATGATCGGCATGGAGCACCCC AAGCTCTTCCATGTGCTGGACTGTACCTGGAACCGGCAGCTGTGCACCTGGTGGAGGGACCATGGCTACAGTGACGTCTTCGAGGCCTAT TTCAGGTGTGAGGGCCACGTCAAGATCTACCACGGGAACTGCAACACTCCCATCCCGGAGGACTAGGCGCTCCCCGTGCCTTGCCCCCGG |
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FusionGenePPI for NF1_SLC46A1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NF1 | HRAS, SMARCA4, POLR2A, TIRAP, SIRT7, VCP, NSFL1C, CAV1, YWHAB, FAF2, NXF1, CCDC8, HLA-DPA1, EFNB2, CD274, TNFSF13B, CA14, SLAMF1, VSIG4, TGOLN2, HTR6, NOSIP, KRAS, CLK1, CDC5L, APP, YWHAH, PML, TRAF6, PTEN, SDC2, EGFR, CD79B, P4HA3, SCN3B, VSIG1, SIGLECL1, EPHA1, FAM174A, KCTD3, KIF13B, ZBTB21, KSR1, CGN, GIGYF1, LRFN1, RTKN, MAST3, DENND1A, SH3PXD2A, SRGAP2, DENND4C, PPM1H, EIF4E2, SIPA1L1, LIMA1, RALGPS2, MAGI1, CBY1, TESK2, CDC25C, DCLK1, GIGYF2, HDAC4, LPIN3, ZNF638, CAMSAP2, NADK, MAPKAP1, SRSF12, RASAL2, SYDE1, KIAA1804, TIAM1, AGAP1, CDC25B, CDK16, SH3RF3, PHLDB2, PLEKHA7, KIF1C, OSBPL6, FAM110B, USP21, NAV1, TANC2, PTPN13, FAM53C, ANKRD34A, STARD13, PTPN14, GAB2, DENND4A, INPP5E, TOP1, TOP2A, TOP3A, NRAS | SLC46A1 | SLC39A4, SLC22A9 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NF1_SLC46A1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NF1_SLC46A1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NF1 | C0027831 | Neurofibromatosis 1 | 34 | CTD_human;ORPHANET;UNIPROT |
| Hgene | NF1 | C2931482 | Neurofibromatosis-Noonan syndrome | 5 | CTD_human;ORPHANET;UNIPROT |
| Hgene | NF1 | C0349639 | Juvenile Myelomonocytic Leukemia | 3 | CTD_human;HPO;ORPHANET |
| Hgene | NF1 | C0004114 | Astrocytoma | 2 | CTD_human;HPO |
| Hgene | NF1 | C0023467 | Leukemia, Myelocytic, Acute | 2 | CTD_human |
| Hgene | NF1 | C0025202 | melanoma | 2 | CTD_human |
| Hgene | NF1 | C0206727 | Nerve Sheath Tumors | 2 | CTD_human |
| Hgene | NF1 | C0001430 | Adenoma | 1 | CTD_human |
| Hgene | NF1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Hgene | NF1 | C0016057 | Fibrosarcoma | 1 | CTD_human |
| Hgene | NF1 | C0017636 | Glioblastoma | 1 | CTD_human |
| Hgene | NF1 | C0017638 | Glioma | 1 | CTD_human |
| Hgene | NF1 | C0023186 | Learning Disorders | 1 | CTD_human |
| Hgene | NF1 | C0023827 | liposarcoma | 1 | CTD_human |
| Hgene | NF1 | C0027809 | Neurilemmoma | 1 | CTD_human |
| Hgene | NF1 | C0027830 | neurofibroma | 1 | CTD_human |
| Hgene | NF1 | C0027962 | Melanocytic nevus | 1 | CTD_human |
| Hgene | NF1 | C0031511 | Pheochromocytoma | 1 | CTD_human |
| Hgene | NF1 | C0162678 | Neurofibromatoses | 1 | CTD_human;HPO |
| Hgene | NF1 | C1261473 | Sarcoma | 1 | CTD_human |
| Hgene | NF1 | C1834235 | NEUROFIBROMATOSIS, FAMILIAL SPINAL | 1 | CTD_human;UNIPROT |
| Hgene | NF1 | C3714756 | Intellectual Disability | 1 | CTD_human;HPO |
| Tgene | SLC46A1 | C0342705 | Folate Malabsorption, Hereditary | 5 | CTD_human;ORPHANET;UNIPROT |
| Tgene | SLC46A1 | C0024523 | Malabsorption Syndrome | 2 | CTD_human |
| Tgene | SLC46A1 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Tgene | SLC46A1 | C0002871 | Anemia | 1 | CTD_human |
| Tgene | SLC46A1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | SLC46A1 | C0030312 | Pancytopenia | 1 | CTD_human |
| Tgene | SLC46A1 | C0598608 | Hyperhomocysteinemia | 1 | CTD_human |
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