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Fusion gene ID: 23987 |
FusionGeneSummary for NEGR1_C1orf173 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NEGR1_C1orf173 | Fusion gene ID: 23987 | Hgene | Tgene | Gene symbol | NEGR1 | C1orf173 | Gene ID | 257194 |
| Gene name | neuronal growth regulator 1 | ||
| Synonyms | DMML2433|IGLON4|KILON|Ntra | ||
| Cytomap | 1p31.1 | ||
| Type of gene | protein-coding | ||
| Description | neuronal growth regulator 1IgLON family member 4a kindred of IgLONneurotractin | ||
| Modification date | 20180522 | ||
| UniProtAcc | Q7Z3B1 | ||
| Ensembl transtripts involved in fusion gene | ENST00000357731, ENST00000306821, ENST00000434200, ENST00000467479, | ENST00000326665, ENST00000433746, ENST00000420661, | |
| Fusion gene scores | * DoF score | 7 X 3 X 6=126 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NEGR1 [Title/Abstract] AND C1orf173 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-OL-A5RW-01A | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000357731 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000357731 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000357731 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-3CDS | ENST00000306821 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000306821 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000306821 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| In-frame | ENST00000434200 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000434200 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| 5CDS-intron | ENST00000434200 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-3CDS | ENST00000467479 | ENST00000326665 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000467479 | ENST00000433746 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
| intron-intron | ENST00000467479 | ENST00000420661 | NEGR1 | chr1 | 72748002 | - | C1orf173 | chr1 | 75114999 | - |
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FusionProtFeatures for NEGR1_C1orf173 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NEGR1 | C1orf173 |
| May be involved in cell-adhesion. May function as atrans-neural growth-promoting factor in regenerative axonsprouting in the mammalian brain (By similarity). {ECO:0000250}. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000326665 | - | 0 | 15 | 254_259 | 7 | 2993 | Compositional bias | Note=Poly-Arg |
| Tgene | >C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000326665 | - | 0 | 15 | 415_1489 | 7 | 2993 | Compositional bias | Note=Glu-rich |
| Tgene | >C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000420661 | - | 0 | 7 | 254_259 | -60 | 534 | Compositional bias | Note=Poly-Arg |
| Tgene | >C1orf173 | chr1:72748002 | chr1:75114999 | ENST00000420661 | - | 0 | 7 | 415_1489 | -60 | 534 | Compositional bias | Note=Glu-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 139_221 | 58 | 355 | Domain | Note=Ig-like C2-type 2 |
| Hgene | >NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 225_313 | 58 | 355 | Domain | Note=Ig-like C2-type 3 |
| Hgene | >NEGR1 | chr1:72748002 | chr1:75114999 | ENST00000357731 | - | 1 | 7 | 38_134 | 58 | 355 | Domain | Note=Ig-like C2-type 1 |
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FusionGeneSequence for NEGR1_C1orf173 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NEGR1_ENST00000357731_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_58aa >In-frame_NEGR1_ENST00000434200_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_56aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NEGR1_ENST00000357731_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_176nt ATGGACATGATGCTGTTGGTGCAGGGTGCTTGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCC >In-frame_NEGR1_ENST00000434200_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_170nt ATGATGCTGTTGGTGCAGGGTGCTTGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCCTGCCTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NEGR1_ENST00000357731_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_7333nt GAAGAGGAGGAGGGGAGGCAAAAACACCGAAAAACAAAAAGAGAGAAACAACACCCAACAACTGGGGTGGGGGGAAGAAAGAAAGAAAAG AAACCCACCCACCCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCCTGTGGCGCGCCGCCTGGTTCCCGGGAAGACTCGCCAG CACCAGGGGGTGGGGGAGTGCGAGCTGAAAGCTGCTGGAGAGTGAGCAGCCCTAGCAGGGATGGACATGATGCTGTTGGTGCAGGGTGCT TGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCCTGCCTCCCGGCTGGACAGAGTGTGGACTTC CCCTGGGCGGCCGTGGACAACATGATGGTCAGAAAAGGGGACACGGCGGTGCTTAGGTTACTTGCTGCATATAATAGCCTTATGGATAAA CACCTGGCTGGGTATTTTAACAATACAAGGATAAGGCGTCATCTCTTAAGATCAGGACTGATCACAAGAAGTGGAAGAATACTTTCTGAA AAAGAATATAAACTAAATATGATGAAGCGGGATCATCAAAAATATATCCGGGAATGCTTAGCCCAGGCAATTTTTCATAAAGTTCTTGAT ATGGAGCGTTACCATCAGCTTGAAATAAAAAAGAAATTGGAGACCTTAGCTAGGAAGGAGCGAATCCAGAGGTTTAAGGGAGAGCACACA AGAAGGTCTGTTGAAAATAACATGCCAATCCTGTCTCCCCACCCACCAGTTGGCCCAAAGAGTAATCGTGGCCATAGTGTTCTGGTTGAT GAAGGACATTCCAGTCCGTTAGCACTGACAGCCCCTCGACCATATACTGCTCCAGGAAATATGCAGCCTCCAATTCGATTACAGCCTCTT CCCAGTAATCCTGCAGTAGAAACTGTTCCAAAGGTAACTTCAAGGTCCAGATCAAAAACCTCATTGCTGGAAAATGAAGCTCTGTTTCCC ATTGGGGGCAAGAAGGCAGTGATGAAGTTCAGGAACTCCATAGGCAATTCACAGAGAATGAATTCATATCAACTTCCAAACATTAACAGT TACATGATGCCTATTCCTCCTCCACTTCCCCCAACTGGGAAAATCACAAGAGAAAATAGATCTGAAACATGGAGAAGGAGAAGATTTCGT CCAACCACTGCTCCAAATGGCTTAGAACCTCTTTTGACAAAGGATTCAAGAAGGATTCATAAAACATCCTTACATAGTAATGCAGCTATT ACAATGATCTATTTGGGGAAAAATGTGCACCTATCTTCTGATAATCCTGACTTCCGGGATGAAATTAAAGTTTATCAGCAGCACTGTGGT GGGGAAAACCTTTGTGTCTACAAAGGCAAACTACTTGAAAAAGAGACCTTTCAGTTTATTTCCAAAAGGCATCATGGTTTCCCCTTCAGT CTCACCTTTTTCCTGAATGGGATGCAGGTGAACAGGTTAAGCTCCTGTTGTGAATACAAGCATCGGAAAGGTTCCAGGCTTGGAGGCAAA CGAGGCTACTTTGGGTTTGTGTGTGTTGAGAGATCATCTCCTTGCTACAAGTGCATTATTGCAATGGGCCTTGACAAAAAACCGTCTTTG CCGAAATCTAGGAAAGAAAAGAGCACTGAGAAAGGAGAGGAACTGAAGAAGGCTGAGGGGAAAGTGAGGAAAGAGAGAGAGTATGTGATA CCAAAAAGAAATGAGATCAAGGAGAACAAAACCTCTGTTTCAGCCAAATTTTCAGCTCAAGAAATAAAAACAGGGCTCAAAGAAGTGGTA ACTGCTGTGGAGGAAATGACAAGTAAAGGAAAACCAGGACAAGAAGTCTTGGAAGACGACCAGGAAAATACTTTAAAATATGAGTATGAA GAAGACTTTGAAGTAGATGAGGAGAAACAAGGTGAAAAATCTAATGAAGAAGGACAGGCTGATGTTCAAATGAATGGAATACCGCAGTCA CCTTTGGATGATAAAAAAGATAATTTAGACCCTGAAAAAGAGAGTGAAACCTCATCACAGAAGGCACCAGATGCCCGTGACAATGTGAAA GATGAGAATGATGGATGCTCTGAGAGTGAACTGGAAGAGGATAAACAAGATATGAAAACTGCTTCATCAACCTCATCCAGAAGTCACCCT TATTCTAGTGACAGTGAGGATGAATCTGCAGTGGGGGACAGGGAAGCCCACACTGACAGCAGCACAGATGAAAGTGCCAGAAGGTCATCT TCTCAGGAACTGAGTGAAAATGATAAGCCAAGAAAGTCTCACCTTCCAATTGAGGAATCCTTAGAAATTGAAATTGAAGACCAAGAAATA ACAAAAGCAGATGTGGAGACCAAGCCGATGCCAATAGACGAAAGCTTTGAGAATGTTCTTAAAGAAGGAACGGAGAAAGGAACCCAAGAG ATTGCAGAGGGTTTATCTGAGAAGTCCGGGAAACATGTTTCTGCAGAAGAAAAGGAAAAGGATAAGAGTAAGCTTTGGGAAGAAAGCACT GCTCAGGTGAAGGACAAAAAGGCAGGTCTCCCTGGGTTGGAGGAAGGTGGAAAGGATTCATTGCCATTAGCCTATGTCCTGGCTCTTGGT GCACCAACAATGAATTTCATGGTGGATGAAACAGCAGCAATCAACTCAAACAAGGAATCCCAGCAATTGGTGCAAAAAACGTATACACTG GAGAAGAAAGAAGCAATGGAGGAAGATGAAGCGCCCCAGCACAGAGATGCTGACATAGTACAGGGAAAAGGGGAGGCAGCACTGTGGGGA GAAGCAGGAGCTGTTCATGAGGCTCCCTTGAGGGCGTGGAAGCCAACAGCAGAGCAGCCAGAATTGGCAGAAGAGTTTACAGAAAAAAGG GAGATCCCTCCAGGCATAGAAAGGGGGGCAGAGGGAGCAGCAGAAGCAGAAGGGGTCAGAAGGCTGGGTGAAGGGGGGTCAGACCCCATA GGACAAGCAGCAGCAAAAGATGCTGTGGGTCTGAGTAAAGATGAGGCTCCTGAAAAGCAAGCCTTGATGCTCACAGTGCTTGAGACAGAC AAAGCAGCTTCTGAAGGGGAACAGGGTTTAGAGAAGGCAGTGCTTGCAAATGAAGCAGCAGCCCTGAACTTGGAGCATCTTCATGAAGTA GCAGCCCTGAGAGAGGCAGCGACATCGGAGGAGGGAGAGGCTGAGGGTGGGGTGGCTGTGAGTGATGTCGGAGAAAGTGAAGAGGAAGCA TCCATAGACCTAGAGGACACAGGACCCATGGAGGACACAGCATCAAAGAGAGAGGACGGTTCTGAAGAGGCAATTCTTGGGGGAGAGGAA CCAGCCAAAGAGAGAAAAGAGGTTATGAGAACAGAAACACGCTTGAGCCCCTTCACAGGAGAGGCAGAGGCAAGCCGGATGCAGGTTTCG GAGGGCAGCCCTGAGGAAGGAAGCCTTGCAAAGGAAGCCTTCCTTTGCAAGGAAGATGTGGAAGGGGAAGAGATGGTGACTGAGGCAGAA GCTAATAGGGAAGATGATAGGAAAGAAATTTTACCCAAGGAATTAGATTTAGCAAGAGAGCGAAGGAAAGCTGAGAGGCCAAAAACATCT CTGAGGAAAACTGACTCTGAGAGAGAAGAGGTGACAAGGGCAAATGCACTCAAGGATGAAGATGCTTTTAAAGAAGAGCAAAAACTTAAA GCGGAAGAAGGGGAAACAGAGACAGAAGTAAGAGCTGAGGAAGAGACAAAAGCTCCCCCAAATGAAATGGGATCTGATGCTGAGAACGAA GCACCTGTGGAGGCTTCTGAGTTGTCTGACAATCCAGGGCTTCTAGGAGAAGATTCACTAAAAGAGACAGTGGTTCCCATATTTGAAGCA ACGCCTGGATTTGAAAAGTCGCTGGAAAACATAACAGCTCTGAGGAAAGAAGGAGGAGGGGAAAGACTGAGTGAAGCCAGAGACACAGAG CACAAAGACAGAGAAGAGCTGTCCAGCAGGGAGAATAGGGCCCTGAAGGAAGGGCACCGCCAAGATGGAGAGGGGGCCTTAGCAGCTCCT GAAGCTGAGCCAGCAGGAAAGGTGCAGGCCCCTGAGGGGCTGATCCCAGCCACAGGCCAGGCAGAGGAGCTAGCAGCCAAAGATCACGAC TCCTGCGCAGGACTGGAGGGGAGAGCTGAAGGGCAAGGAGGAGTGGATGTCGTGCTAAGGACCCAGGAAGCTGTTGCTGAGGAAGATCCC ATAATGGCAGAAAAGTTCAGGGAGGAAGCGGTGGATGAGGACCCAGAGGAGGAAGAGGACAAAGAGTGCACTCTGGAGACAGAAGCGATG CAGGACAGGAACTCGGAAGGGGACGGGGACATGGAAGGAGAAGGAAACACACAAAAGAATGAGGGCATGGGAGGAGGAAGGGTTGTGGCT GTGGAAGTTCTACACGGAGGTGGTGAAACGGCAGAAACAGCCGCAGAGGAGAGGGAGGTGTTGGCAGGTTCGGAGACAGCCGAGGAGAAA ACAATAGCAAATAAAGCCTCCTCCTTTTCAGATGTTGCTGAGGAAGAAACCTGGCACCAACAGGATGAGTTAGTAGGAAAAACAGCAGCT GCAGGGAAGGTGGTGGTAGAGGAATTAGCACGGAGTGGGGAGGAAGTGCCAGCAGCAGAGGAGATGACAGTGACATATACAACAGAGGCT GGGGTGGGCACTCCAGGAGCCCTGGAGCGGAAGACCTCAGGGCTAGGACAGGAGCAAGAGGAAGGGTCAGAGGGCCAGGAGGCAGCCACT GGGAGTGGCGATGGGAGGCAGGAGACAGGAGCAGCTGAAAAATTCCGATTAGGATTATCACGGGAGGGAGAGAGGGAATTGAGTCCGGAG AGTCTACAGGCGATGGCAACACTTCCAGTGAAGCCTGATTTCACTGAAACCCGAGAGAAGCAACAGCATATGGTGCAAGGAGAAAGCGAG ACTGCAGATGTTTCCCCCAACAACGTGCAGGTCTAGGAGACTTGCTGGCAGACAGATAATTTAAAGATGTCTTCTGAAGATGTAAAGAGT GGAGAAAGATTCACGCAAGCATCTCACCAGGATTCTTGATTTTCTCTCTCTCCTCTTTAGTTGCTGGTTGCGCTTGTCTGAGATGATTCC CAATCTGTCAGCCCTGGTCAGTAGCTCAGTAAGCACCTTGAGAATAGCTCAAGTAGATCTGTAGGACCCTTCTTAGAAGCAGTGGTTCCT CATGGAGAAACTTGTGAGGCTGTTACACATTCTACACACCTAACATTATTTTCAAACAAAAATGATAATTTTCAGATGCTTGACTTTTAC CAAAGATCACTGGAAGGCCCAGTCCTAATGTTAGGGGTTTGTTTAAAGTCCTTTTTATTTTACAATACAGAGCCCCAGTCAATTCCACAA TCTCAATTTCATACATGGGAATTTTATTTAAAAATCTGTGGTTTGGGGCTTTAATGAATTGGCCTGTGAAAATGAGCTCTAAATTTCCTC CCACGTACACTCAAAACTCAAGATTGCTCCAAATCTCTAAGTTCTTCCAGCAAAAGATTTCTTGGCATGTATATTCACTTATACTTAGAA ATATTCATTCTTTTAATTTATGCCAGAATAACAAAGTGGAAATCTTATTTCAAAATGCTCTTTGTTTTTTTGTGTGTGTTTCTGTAGTTC TGCTTTCTGGGGTAGACTAGTAAAATGGTAGCTTCCAGCATTTTGTCCCTGGGGCCTTCTTTATAGGGCCACTCAAATTTAAATAAAAGT AGTAAATAATTTAGCTAAGTGGAATAAGTATAATAATTATAGTGGTAAGCATAGCACATCAGCATTATGCCAACATTCTAGACTCTTTAG TTGATGTCATTAAATGGAAAAGAAACTTGGATTAAATGAGTGTGCTGCTCACCTTCCCAAGTTCTGTTATTTCAAACCTGTGAACTAACC TTGCAGTTCATTATAAATCAACAGTAACAACTGCATTCTAAATTACTCCCTGATATTATTTTCTAGTTGTGTATCAGCCTGTCTCCTAGG GGTTTTCATTTCCCTGAAGACATACAAGTGCCCCAGAGCGCATGTATATGTCTACCATTTCTCTATATGAGAAGGTAAAAAAAATTTCCT TAAGCAGTGATTTTCCAGCCAGAATATACATTAGATTTTCATGGGACGCTTTTATAAATGACTCAACCCTTTTCCCCACCCCAGAGATTC AGACTTAATTCGTTTTAGATGGATCTACACATCAGTATATATATATTTTTAACTTTTCACTTGATTCTTCTCTGTAGCCAAGGTTGAGAA CCGCTGTTCTAAATCATCATATAATCCATGCTGGCCACATTACACTCAAGGTCCCTAGGGACCAGGCATATTATCATAGTAGGTATTTTC CATTTTAATGTGTAATGGAGCCATTCAATGATCAAAAATACACTGGACCAGATAGTAGACTGGTCCCTTGATCAGAAGCATCAGCACATC AGCATCACCTGGAAATTGTTCCCAGCCTTTGTCTCCTACCTACTAAATTAGAAACTCTTGGTGGGTTCCAGTAATCCATAGCTTAACAAG CCCTGCAGTTAATACTGATGTACACTGATGTCCAAAAACTGCTGTCATGGACTATTGATTGTATTGAGGATTAGTCTCAGTTGGAAAGCC AACTACAGAGGCATTTTGAACTTTCTTTCTTTGCCTCTCTATGTCTCTCTGTCTTTTCCTGTCTTCTGATTTATCTGTCTTTCTTTCTCT AGTAAATGGCACTCAATATAAAAGTGGTGGAGTCAATCTTAAACTTATTTTTATTATGATTGTATTGATACATGCACGAAGTCCCTCTGC CCTACTCCCTATTCAAGGATATTACTCACTGCACATCATAAATCTCCATCATCTGTCTTAAAGTTTTATGAGTAGATTTCATCTACATTA TATTCAAGTTCATTTATTACTGAGCTGTATTACTGTGGAGCTCTAACAGTATTTGTTTCCTGATTTCAAACTCAATGCTACAGAGCACTT TGAATACATCACACCTTATAGGAAAGATAGTAAATGTATTAATCCCATTGAAAAATTAGTTTTGTACAATGTGCTAAATAGTATTGCATT GGATTACTTTTATATTTAACACACTCCATCAAAACATCCCATAACATAATTTTACAATCTGCATGTGAATTTAACTGTGAAATTCAGTAT TGTGATATTTTGAATAAGTGAATTCTTTCTCTGCAAATACTATGTTGATAAAATTACTTGTATGTTCCCCTGAAATGGTTTGTTTCCTGT >In-frame_NEGR1_ENST00000434200_chr1_72748002_-_C1orf173_ENST00000326665_chr1_75114999_-_7087nt ATGATGCTGTTGGTGCAGGGTGCTTGTTGCTCGAACCAGTGGCTGGCGGCGGTGCTCCTCAGCCTGTGCTGCCTGCTACCCTCCTGCCTC CCGGCTGGACAGAGTGTGGACTTCCCCTGGGCGGCCGTGGACAACATGATGGTCAGAAAAGGGGACACGGCGGTGCTTAGGTTACTTGCT GCATATAATAGCCTTATGGATAAACACCTGGCTGGGTATTTTAACAATACAAGGATAAGGCGTCATCTCTTAAGATCAGGACTGATCACA AGAAGTGGAAGAATACTTTCTGAAAAAGAATATAAACTAAATATGATGAAGCGGGATCATCAAAAATATATCCGGGAATGCTTAGCCCAG GCAATTTTTCATAAAGTTCTTGATATGGAGCGTTACCATCAGCTTGAAATAAAAAAGAAATTGGAGACCTTAGCTAGGAAGGAGCGAATC CAGAGGTTTAAGGGAGAGCACACAAGAAGGTCTGTTGAAAATAACATGCCAATCCTGTCTCCCCACCCACCAGTTGGCCCAAAGAGTAAT CGTGGCCATAGTGTTCTGGTTGATGAAGGACATTCCAGTCCGTTAGCACTGACAGCCCCTCGACCATATACTGCTCCAGGAAATATGCAG CCTCCAATTCGATTACAGCCTCTTCCCAGTAATCCTGCAGTAGAAACTGTTCCAAAGGTAACTTCAAGGTCCAGATCAAAAACCTCATTG CTGGAAAATGAAGCTCTGTTTCCCATTGGGGGCAAGAAGGCAGTGATGAAGTTCAGGAACTCCATAGGCAATTCACAGAGAATGAATTCA TATCAACTTCCAAACATTAACAGTTACATGATGCCTATTCCTCCTCCACTTCCCCCAACTGGGAAAATCACAAGAGAAAATAGATCTGAA ACATGGAGAAGGAGAAGATTTCGTCCAACCACTGCTCCAAATGGCTTAGAACCTCTTTTGACAAAGGATTCAAGAAGGATTCATAAAACA TCCTTACATAGTAATGCAGCTATTACAATGATCTATTTGGGGAAAAATGTGCACCTATCTTCTGATAATCCTGACTTCCGGGATGAAATT AAAGTTTATCAGCAGCACTGTGGTGGGGAAAACCTTTGTGTCTACAAAGGCAAACTACTTGAAAAAGAGACCTTTCAGTTTATTTCCAAA AGGCATCATGGTTTCCCCTTCAGTCTCACCTTTTTCCTGAATGGGATGCAGGTGAACAGGTTAAGCTCCTGTTGTGAATACAAGCATCGG AAAGGTTCCAGGCTTGGAGGCAAACGAGGCTACTTTGGGTTTGTGTGTGTTGAGAGATCATCTCCTTGCTACAAGTGCATTATTGCAATG GGCCTTGACAAAAAACCGTCTTTGCCGAAATCTAGGAAAGAAAAGAGCACTGAGAAAGGAGAGGAACTGAAGAAGGCTGAGGGGAAAGTG AGGAAAGAGAGAGAGTATGTGATACCAAAAAGAAATGAGATCAAGGAGAACAAAACCTCTGTTTCAGCCAAATTTTCAGCTCAAGAAATA AAAACAGGGCTCAAAGAAGTGGTAACTGCTGTGGAGGAAATGACAAGTAAAGGAAAACCAGGACAAGAAGTCTTGGAAGACGACCAGGAA AATACTTTAAAATATGAGTATGAAGAAGACTTTGAAGTAGATGAGGAGAAACAAGGTGAAAAATCTAATGAAGAAGGACAGGCTGATGTT CAAATGAATGGAATACCGCAGTCACCTTTGGATGATAAAAAAGATAATTTAGACCCTGAAAAAGAGAGTGAAACCTCATCACAGAAGGCA CCAGATGCCCGTGACAATGTGAAAGATGAGAATGATGGATGCTCTGAGAGTGAACTGGAAGAGGATAAACAAGATATGAAAACTGCTTCA TCAACCTCATCCAGAAGTCACCCTTATTCTAGTGACAGTGAGGATGAATCTGCAGTGGGGGACAGGGAAGCCCACACTGACAGCAGCACA GATGAAAGTGCCAGAAGGTCATCTTCTCAGGAACTGAGTGAAAATGATAAGCCAAGAAAGTCTCACCTTCCAATTGAGGAATCCTTAGAA ATTGAAATTGAAGACCAAGAAATAACAAAAGCAGATGTGGAGACCAAGCCGATGCCAATAGACGAAAGCTTTGAGAATGTTCTTAAAGAA GGAACGGAGAAAGGAACCCAAGAGATTGCAGAGGGTTTATCTGAGAAGTCCGGGAAACATGTTTCTGCAGAAGAAAAGGAAAAGGATAAG AGTAAGCTTTGGGAAGAAAGCACTGCTCAGGTGAAGGACAAAAAGGCAGGTCTCCCTGGGTTGGAGGAAGGTGGAAAGGATTCATTGCCA TTAGCCTATGTCCTGGCTCTTGGTGCACCAACAATGAATTTCATGGTGGATGAAACAGCAGCAATCAACTCAAACAAGGAATCCCAGCAA TTGGTGCAAAAAACGTATACACTGGAGAAGAAAGAAGCAATGGAGGAAGATGAAGCGCCCCAGCACAGAGATGCTGACATAGTACAGGGA AAAGGGGAGGCAGCACTGTGGGGAGAAGCAGGAGCTGTTCATGAGGCTCCCTTGAGGGCGTGGAAGCCAACAGCAGAGCAGCCAGAATTG GCAGAAGAGTTTACAGAAAAAAGGGAGATCCCTCCAGGCATAGAAAGGGGGGCAGAGGGAGCAGCAGAAGCAGAAGGGGTCAGAAGGCTG GGTGAAGGGGGGTCAGACCCCATAGGACAAGCAGCAGCAAAAGATGCTGTGGGTCTGAGTAAAGATGAGGCTCCTGAAAAGCAAGCCTTG ATGCTCACAGTGCTTGAGACAGACAAAGCAGCTTCTGAAGGGGAACAGGGTTTAGAGAAGGCAGTGCTTGCAAATGAAGCAGCAGCCCTG AACTTGGAGCATCTTCATGAAGTAGCAGCCCTGAGAGAGGCAGCGACATCGGAGGAGGGAGAGGCTGAGGGTGGGGTGGCTGTGAGTGAT GTCGGAGAAAGTGAAGAGGAAGCATCCATAGACCTAGAGGACACAGGACCCATGGAGGACACAGCATCAAAGAGAGAGGACGGTTCTGAA GAGGCAATTCTTGGGGGAGAGGAACCAGCCAAAGAGAGAAAAGAGGTTATGAGAACAGAAACACGCTTGAGCCCCTTCACAGGAGAGGCA GAGGCAAGCCGGATGCAGGTTTCGGAGGGCAGCCCTGAGGAAGGAAGCCTTGCAAAGGAAGCCTTCCTTTGCAAGGAAGATGTGGAAGGG GAAGAGATGGTGACTGAGGCAGAAGCTAATAGGGAAGATGATAGGAAAGAAATTTTACCCAAGGAATTAGATTTAGCAAGAGAGCGAAGG AAAGCTGAGAGGCCAAAAACATCTCTGAGGAAAACTGACTCTGAGAGAGAAGAGGTGACAAGGGCAAATGCACTCAAGGATGAAGATGCT TTTAAAGAAGAGCAAAAACTTAAAGCGGAAGAAGGGGAAACAGAGACAGAAGTAAGAGCTGAGGAAGAGACAAAAGCTCCCCCAAATGAA ATGGGATCTGATGCTGAGAACGAAGCACCTGTGGAGGCTTCTGAGTTGTCTGACAATCCAGGGCTTCTAGGAGAAGATTCACTAAAAGAG ACAGTGGTTCCCATATTTGAAGCAACGCCTGGATTTGAAAAGTCGCTGGAAAACATAACAGCTCTGAGGAAAGAAGGAGGAGGGGAAAGA CTGAGTGAAGCCAGAGACACAGAGCACAAAGACAGAGAAGAGCTGTCCAGCAGGGAGAATAGGGCCCTGAAGGAAGGGCACCGCCAAGAT GGAGAGGGGGCCTTAGCAGCTCCTGAAGCTGAGCCAGCAGGAAAGGTGCAGGCCCCTGAGGGGCTGATCCCAGCCACAGGCCAGGCAGAG GAGCTAGCAGCCAAAGATCACGACTCCTGCGCAGGACTGGAGGGGAGAGCTGAAGGGCAAGGAGGAGTGGATGTCGTGCTAAGGACCCAG GAAGCTGTTGCTGAGGAAGATCCCATAATGGCAGAAAAGTTCAGGGAGGAAGCGGTGGATGAGGACCCAGAGGAGGAAGAGGACAAAGAG TGCACTCTGGAGACAGAAGCGATGCAGGACAGGAACTCGGAAGGGGACGGGGACATGGAAGGAGAAGGAAACACACAAAAGAATGAGGGC ATGGGAGGAGGAAGGGTTGTGGCTGTGGAAGTTCTACACGGAGGTGGTGAAACGGCAGAAACAGCCGCAGAGGAGAGGGAGGTGTTGGCA GGTTCGGAGACAGCCGAGGAGAAAACAATAGCAAATAAAGCCTCCTCCTTTTCAGATGTTGCTGAGGAAGAAACCTGGCACCAACAGGAT GAGTTAGTAGGAAAAACAGCAGCTGCAGGGAAGGTGGTGGTAGAGGAATTAGCACGGAGTGGGGAGGAAGTGCCAGCAGCAGAGGAGATG ACAGTGACATATACAACAGAGGCTGGGGTGGGCACTCCAGGAGCCCTGGAGCGGAAGACCTCAGGGCTAGGACAGGAGCAAGAGGAAGGG TCAGAGGGCCAGGAGGCAGCCACTGGGAGTGGCGATGGGAGGCAGGAGACAGGAGCAGCTGAAAAATTCCGATTAGGATTATCACGGGAG GGAGAGAGGGAATTGAGTCCGGAGAGTCTACAGGCGATGGCAACACTTCCAGTGAAGCCTGATTTCACTGAAACCCGAGAGAAGCAACAG CATATGGTGCAAGGAGAAAGCGAGACTGCAGATGTTTCCCCCAACAACGTGCAGGTCTAGGAGACTTGCTGGCAGACAGATAATTTAAAG ATGTCTTCTGAAGATGTAAAGAGTGGAGAAAGATTCACGCAAGCATCTCACCAGGATTCTTGATTTTCTCTCTCTCCTCTTTAGTTGCTG GTTGCGCTTGTCTGAGATGATTCCCAATCTGTCAGCCCTGGTCAGTAGCTCAGTAAGCACCTTGAGAATAGCTCAAGTAGATCTGTAGGA CCCTTCTTAGAAGCAGTGGTTCCTCATGGAGAAACTTGTGAGGCTGTTACACATTCTACACACCTAACATTATTTTCAAACAAAAATGAT AATTTTCAGATGCTTGACTTTTACCAAAGATCACTGGAAGGCCCAGTCCTAATGTTAGGGGTTTGTTTAAAGTCCTTTTTATTTTACAAT ACAGAGCCCCAGTCAATTCCACAATCTCAATTTCATACATGGGAATTTTATTTAAAAATCTGTGGTTTGGGGCTTTAATGAATTGGCCTG TGAAAATGAGCTCTAAATTTCCTCCCACGTACACTCAAAACTCAAGATTGCTCCAAATCTCTAAGTTCTTCCAGCAAAAGATTTCTTGGC ATGTATATTCACTTATACTTAGAAATATTCATTCTTTTAATTTATGCCAGAATAACAAAGTGGAAATCTTATTTCAAAATGCTCTTTGTT TTTTTGTGTGTGTTTCTGTAGTTCTGCTTTCTGGGGTAGACTAGTAAAATGGTAGCTTCCAGCATTTTGTCCCTGGGGCCTTCTTTATAG GGCCACTCAAATTTAAATAAAAGTAGTAAATAATTTAGCTAAGTGGAATAAGTATAATAATTATAGTGGTAAGCATAGCACATCAGCATT ATGCCAACATTCTAGACTCTTTAGTTGATGTCATTAAATGGAAAAGAAACTTGGATTAAATGAGTGTGCTGCTCACCTTCCCAAGTTCTG TTATTTCAAACCTGTGAACTAACCTTGCAGTTCATTATAAATCAACAGTAACAACTGCATTCTAAATTACTCCCTGATATTATTTTCTAG TTGTGTATCAGCCTGTCTCCTAGGGGTTTTCATTTCCCTGAAGACATACAAGTGCCCCAGAGCGCATGTATATGTCTACCATTTCTCTAT ATGAGAAGGTAAAAAAAATTTCCTTAAGCAGTGATTTTCCAGCCAGAATATACATTAGATTTTCATGGGACGCTTTTATAAATGACTCAA CCCTTTTCCCCACCCCAGAGATTCAGACTTAATTCGTTTTAGATGGATCTACACATCAGTATATATATATTTTTAACTTTTCACTTGATT CTTCTCTGTAGCCAAGGTTGAGAACCGCTGTTCTAAATCATCATATAATCCATGCTGGCCACATTACACTCAAGGTCCCTAGGGACCAGG CATATTATCATAGTAGGTATTTTCCATTTTAATGTGTAATGGAGCCATTCAATGATCAAAAATACACTGGACCAGATAGTAGACTGGTCC CTTGATCAGAAGCATCAGCACATCAGCATCACCTGGAAATTGTTCCCAGCCTTTGTCTCCTACCTACTAAATTAGAAACTCTTGGTGGGT TCCAGTAATCCATAGCTTAACAAGCCCTGCAGTTAATACTGATGTACACTGATGTCCAAAAACTGCTGTCATGGACTATTGATTGTATTG AGGATTAGTCTCAGTTGGAAAGCCAACTACAGAGGCATTTTGAACTTTCTTTCTTTGCCTCTCTATGTCTCTCTGTCTTTTCCTGTCTTC TGATTTATCTGTCTTTCTTTCTCTAGTAAATGGCACTCAATATAAAAGTGGTGGAGTCAATCTTAAACTTATTTTTATTATGATTGTATT GATACATGCACGAAGTCCCTCTGCCCTACTCCCTATTCAAGGATATTACTCACTGCACATCATAAATCTCCATCATCTGTCTTAAAGTTT TATGAGTAGATTTCATCTACATTATATTCAAGTTCATTTATTACTGAGCTGTATTACTGTGGAGCTCTAACAGTATTTGTTTCCTGATTT CAAACTCAATGCTACAGAGCACTTTGAATACATCACACCTTATAGGAAAGATAGTAAATGTATTAATCCCATTGAAAAATTAGTTTTGTA CAATGTGCTAAATAGTATTGCATTGGATTACTTTTATATTTAACACACTCCATCAAAACATCCCATAACATAATTTTACAATCTGCATGT GAATTTAACTGTGAAATTCAGTATTGTGATATTTTGAATAAGTGAATTCTTTCTCTGCAAATACTATGTTGATAAAATTACTTGTATGTT |
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FusionGenePPI for NEGR1_C1orf173 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NEGR1 | NTM, LSAMP, NEGR1 | C1orf173 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NEGR1_C1orf173 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NEGR1_C1orf173 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NEGR1 | C0028754 | Obesity | 1 | CTD_human |
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