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Fusion gene ID: 23564 |
FusionGeneSummary for NCAPG_NCAPG |
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Fusion gene information | Fusion gene name: NCAPG_NCAPG | Fusion gene ID: 23564 | Hgene | Tgene | Gene symbol | NCAPG | NCAPG | Gene ID | 64151 | 64151 |
Gene name | non-SMC condensin I complex subunit G | non-SMC condensin I complex subunit G | |
Synonyms | CAPG|CHCG|NY-MEL-3|YCG1 | CAPG|CHCG|NY-MEL-3|YCG1 | |
Cytomap | 4p15.31 | 4p15.31 | |
Type of gene | protein-coding | protein-coding | |
Description | condensin complex subunit 3XCAP-G homologchromosome condensation protein Gchromosome-associated protein Gcondensin subunit CAP-Gmelanoma antigen NY-MEL-3 | condensin complex subunit 3XCAP-G homologchromosome condensation protein Gchromosome-associated protein Gcondensin subunit CAP-Gmelanoma antigen NY-MEL-3 | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | Q9BPX3 | Q9BPX3 | |
Ensembl transtripts involved in fusion gene | ENST00000251496, | ENST00000251496, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
# samples | 1 | 1 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: NCAPG [Title/Abstract] AND NCAPG [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | NCAPG | GO:0007076 | mitotic chromosome condensation | 11136719 |
Tgene | NCAPG | GO:0007076 | mitotic chromosome condensation | 11136719 |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AW794691 | NCAPG | chr4 | 17844002 | + | NCAPG | chr4 | 17841698 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000251496 | ENST00000251496 | NCAPG | chr4 | 17844002 | + | NCAPG | chr4 | 17841698 | + |
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FusionProtFeatures for NCAPG_NCAPG |
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Hgene | Tgene |
NCAPG | NCAPG |
Regulatory subunit of the condensin complex, a complexrequired for conversion of interphase chromatin into mitotic-likecondense chromosomes. The condensin complex probably introducespositive supercoils into relaxed DNA in the presence of type Itopoisomerases and converts nicked DNA into positive knotted formsin the presence of type II topoisomerases.{ECO:0000269|PubMed:11136719}. | Regulatory subunit of the condensin complex, a complexrequired for conversion of interphase chromatin into mitotic-likecondense chromosomes. The condensin complex probably introducespositive supercoils into relaxed DNA in the presence of type Itopoisomerases and converts nicked DNA into positive knotted formsin the presence of type II topoisomerases.{ECO:0000269|PubMed:11136719}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NCAPG_NCAPG |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for NCAPG_NCAPG |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
NCAPG | PTP4A3, DNMT3B, NPM1, PARP1, XRCC1, FEN1, LIG3, POLD1, POLB, RAD21, NCAPD2, SMC2, NCAPH, SMC4, CDK1, CUL3, PAXIP1, EPS15L1, CCAR2, PLEC, EGFR, TNFSF13B, ARPC1A, MAGIX, GPR137B, ARRDC1, HTR6, NTRK1, MED4, MED20, MED23, FOXA3, FOXL1, ESR1, UBC, DTX3L, HECTD1, NCAPH2, SNW1, PPP3CA, DPEP1, BMP1, INTU, FZD10, MAS1, FUZ, HTR2C, CDH19, CHRM4, C3AR1, AARSD1 | NCAPG | PTP4A3, DNMT3B, NPM1, PARP1, XRCC1, FEN1, LIG3, POLD1, POLB, RAD21, NCAPD2, SMC2, NCAPH, SMC4, CDK1, CUL3, PAXIP1, EPS15L1, CCAR2, PLEC, EGFR, TNFSF13B, ARPC1A, MAGIX, GPR137B, ARRDC1, HTR6, NTRK1, MED4, MED20, MED23, FOXA3, FOXL1, ESR1, UBC, DTX3L, HECTD1, NCAPH2, SNW1, PPP3CA, DPEP1, BMP1, INTU, FZD10, MAS1, FUZ, HTR2C, CDH19, CHRM4, C3AR1, AARSD1 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NCAPG_NCAPG |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NCAPG_NCAPG |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |