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Fusion gene ID: 23562 |
FusionGeneSummary for NCAPG2_N4BP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NCAPG2_N4BP2 | Fusion gene ID: 23562 | Hgene | Tgene | Gene symbol | NCAPG2 | N4BP2 | Gene ID | 54892 | 55728 |
| Gene name | non-SMC condensin II complex subunit G2 | NEDD4 binding protein 2 | |
| Synonyms | CAP-G2|CAPG2|LUZP5|MTB|hCAP-G2 | B3BP | |
| Cytomap | 7q36.3 | 4p14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | condensin-2 complex subunit G2chromosome-associated protein G2leucine zipper protein 5more than blood homolog | NEDD4-binding protein 2BCL-3-binding protein | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q86XI2 | Q86UW6 | |
| Ensembl transtripts involved in fusion gene | ENST00000356309, ENST00000409423, ENST00000275830, ENST00000409339, ENST00000449727, ENST00000541468, ENST00000479022, | ENST00000261435, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 2 X 3 X 1=6 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/6*10)=2.32192809488736 | |
| Context | PubMed: NCAPG2 [Title/Abstract] AND N4BP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E9-A1R6-01A | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000356309 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| In-frame | ENST00000409423 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| intron-3CDS | ENST00000275830 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| Frame-shift | ENST00000409339 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| In-frame | ENST00000449727 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| intron-3CDS | ENST00000541468 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
| intron-3CDS | ENST00000479022 | ENST00000261435 | NCAPG2 | chr7 | 158494513 | - | N4BP2 | chr4 | 40154400 | + |
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FusionProtFeatures for NCAPG2_N4BP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NCAPG2 | N4BP2 |
| Regulatory subunit of the condensin-2 complex, a complexwhich establishes mitotic chromosome architecture and is involvedin physical rigidity of the chromatid axis.{ECO:0000269|PubMed:14532007}. | Has 5'-polynucleotide kinase and nicking endonucleaseactivity. May play a role in DNA repair or recombination.{ECO:0000269|PubMed:12730195}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NCAPG2_N4BP2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NCAPG2_ENST00000409423_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_82aa >In-frame_NCAPG2_ENST00000449727_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_82aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NCAPG2_ENST00000409423_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_248nt ATGGAAAAACGTGAGACGTTTGTACAAGCCGTGTCTAAGGAGCTGGTTGGAGAGTTTTTGCAATTTGTTCAACTTGATAATTTAAGCAGA ACGGTGGGAAGCCCTATTTGTCTGTGATTACGGGGAGAGGAAACCACAGCCAGGGAGGAGTTGCTCGCATCAAACCAGCTGTCATTAAGT >In-frame_NCAPG2_ENST00000449727_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_248nt ATGGAAAAACGTGAGACGTTTGTACAAGCCGTGTCTAAGGAGCTGGTTGGAGAGTTTTTGCAATTTGTTCAACTTGATAATTTAAGCAGA ACGGTGGGAAGCCCTATTTGTCTGTGATTACGGGGAGAGGAAACCACAGCCAGGGAGGAGTTGCTCGCATCAAACCAGCTGTCATTAAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NCAPG2_ENST00000409423_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_4436nt GAGGGCGGGGCCCGTCTGGGGCGCCGGCGGGTGCGTTTGAATCTGGTCCGAGCGCGGGAAACGGCGGGTCCCCGAGCCCAGTACCAGACC TCCTGTGCGAAGAGTAACCTGCTCTTCGGACTGATAACTGGATGGGTTACAAAATAAATGCCATTTGAACAGTGCCATCTGTCATGGAAA AACGTGAGACGTTTGTACAAGCCGTGTCTAAGGAGCTGGTTGGAGAGTTTTTGCAATTTGTTCAACTTGATAATTTAAGCAGAACGGTGG GAAGCCCTATTTGTCTGTGATTACGGGGAGAGGAAACCACAGCCAGGGAGGAGTTGCTCGCATCAAACCAGCTGTCATTAAGTACCTCAT AAGCCATAGCTTCAGGTTCTCTGAAATTAAACCAGGGTGCTTGAAAGTCATGCTAAAGTAAAATAAACATCCTTGAATTAGAAGTATGAA GGTTTGTAGGTTAAAATTACTTTTATTTGCAGTAATTCAGTCAATTCTACCCTAAAGATGTGTTTTATTATAAATAATATTCAATTATGA AACAAAAAAATTATGATGTTTTTCAAAATGCAAGTGAGGTTTGATTTTTTACTGAATCAAATGCAAATGTTACCTGTTAAAGATATTACA GAGAAATTTTATTGATTACAAAATATGTAAGAAAATTATCAGCTACAGTTTTAAAGTTTAAAATGCTCTGATTGTTTCTCAGAAAAGGTT ACCTTTGTATTAATTGTTGTATGACATTTAGTAATGTCCTAAAAGTCTTTTGTGAGAGGTATTTAAAGTGCTTTGAGACCTGATTCATGC CCCCCAAAGGGTGGTATTAAAAGAGGAAAAAGGACATAGTAGTGGTAGTAAAGAAAAAAAGGAGATCTAACAAAAACACTTGAATATTTT TTATTTTCAAAACTAAACACATAAAATGCTTTTATTTTGCCATATCCTACAGGAAGGAAGACATGCTTTTGCCCTTTCTTCTGCTTTGTA TATGACCTTGATCTTTTACCTTTTGTTCTGTTCTTCTGTGTGCATTTTATGGAAAGAAAGTTGGGTCTGAGATTATATTGTAATTTTATA CTTTCTATAGACAGAAAGGTTTTCAGAGAAAAAGAAATGGTTAAATATCTTCCAGATGTTGCTGCCTTATCGAAATGCTTCTAGAACTGT CTGTATAAGTCGTATTTCAGACAGTACTAAATACTTATATTTTATTTTTGAGGCATGTAATTTTAAAACTGCAGTAGGTTAAAATTCTAT TAAACAAATATAGAAAATATTTTGTTTATAATTGGCCTGGTGTGGTGGCCCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTAGGT GGATCGCCTGAGGTCAGAAGTTCAAGACCAGCCTGGCCAACATGGTGAATCCCCGTCTCTATTAAAAATACAAAAATTAGCTGGGTGTGG TGGCGTGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAACCGCTTAAACCTGGGAGGTGGAGGTTGCAGTGACCCGAGATC GAGATCACACCACTGCACTCAGCCTGGGTGACAGAGCAAGACTCCGTCTCCAAAAAAAAAAAAGAAAAAAAAGAGAAAATATTTTGGTTA TAATCATAAGAAGAATCCTTACAATTTAAAATATTTTCACTTTTATTTTGAAAAAGAGCCAACTTTCTCAAAGGAAGCTGTCATTAACTT CTGTTGTTTGGTTAGCTAATAAATTCTGTTAGTATGCAAGTTAAACCTGTGTAAAGGAGGTTATAATGTGGTAAGGTATAATTTTCCAAT ATGAGACAATGGCTTAAATTTGCCTTTGGAGATGGAGAATATTTTCAACATACATAATTTTAACAAATAGTTTTGTTGCTTTTTGTTAAG CTTAAAAAAAAATTTGGATCAGAAATTATAGGATTGAGCTGGTACCAAAAGAATCCTAAAGTACAGAATGGTTTTCCAAAAGAGCAGACA TTTCAATGAAAATAAAACCCCAAAACATTTTTTTTATATATCATGATTGCATGCTTTTAAAATAAGGAGGCTTATCATTGAATTTTAGTT CCATAAAAATGAAAATACATGTTTATTATTTAGAAATGGTTAGTGACTGGTATTGAAGTATTATTCACACTTATGTTTGTAATAATTTAT TTAAAGAATGCCAACAGTTTAGCACACTTTTGTAATCTCTAGAACAGTTCTATACATTAAAAATAAACATTAAAAATAAAGCAGTTCCTT TAAACAACTTACTATGAAACTATAATTGTTAATGAAATAAGATATTCCTATGTATACATTAGTATGATTTAAGGGTATGAAAAACAGTGC TAAAATGTGGAGTTAATTGGAATGTGTGCAGCTGCATACTCACTTTCTGTGTTTTTATATTTCCTTACCTAGTTTTAAAAATCATCACTT TTCGGCACTTCAGCTAGACTTATTTCAATATTATAATTATGATTAATGAAGGAGCAGTCAGAAGTAGAGGTGTGGTATTCCGTGGGCAGA AGTCAAATGAAAAAAGCTATATTGTTTACTTGTTTACTATATCAATGTTAATATTATGCCTTATTTTGATAAATCAAATAGTATATCTTA ATCATTGTTGATAAATATACAGGCAAAGTTTGAGCATCATATGTATTTTTATGAAGCTGCTTAATTCCAAATTGCCTCCCACCCCACTAT CTAGCATAGTTTAAGCAACACATAATTTTGAAAGAAAAGTTTGTAATCCCTCCTTTCTTTTTTTTGCCCATTTCTAAATCCTGTATGCCC GCAGTAAAGATAGTTTGGGGATTTTAAAAGTTTTCTCTATTACCCATTTCTAAATCCTGTATGTCAAAGATAGTTTGGAGATTATAAAAA TTTTCATGTATTGGTGTAGGTTGAGTATCCCTAATGAGAAAATTCAAAATCTGAAATGCTTCAAAATCTGAAATTTTTCGAGCACAGACA TGATGCTCAAAGGAAATACTCACAGAGCATTTTACATTTGTAGGTTAGCGATACTCAACAAGTAAATATAATGCACATGTTCTAAAATAT CCCCCCAAACCCCAGCAATCCAAAACACTTCTGGTCCTAAGCATTTTGAGTAGGGGATACTCACTCAACCTGTATATTTGTGCTAATACA TGACTCATTAGAATGATTCTTTGTAAACTTAATATTTTAAAAGTACAGCACTTCTGTAGTATGGAAGGTTTCAGTAATAATTATATTCAT TCAGTAGTCTCTTACCATTATCTCCCAGATGGAAAAAGAGGACTAATGTGGAAACCCCAGAGGGTGTCCAGTTGGACCAGGGAGATATTA GACACTTAACAGTATTTTCAGTCTGTCCATCTCTTTATTCCAATGTGAGAAATGGAAGTGTTTTTTTTTTTACGTTTATTGGCTCTTCAT ATTTCTCTACATTATTTTTAATGTGCAGTTTCTTCAATTGGTTAGTATTTCCATACTATTTGCAACTTTATGGCCTTTAAATATAGGACA TATTATATAGCAGAAATTTTGACTTTAAATCCTCTTGAGTAGTATATTTTGAGAAGAAAAGCTATACTGCTCTTCTGGATGGTTTCCATC CTTTATTTAGGTCTTTTCTTTTTGAATTCAAGTGTTTTGTATGCTTAGAAAGTAGACATGTATAATATTGAGATCGGTTATTTCTGAGCT GGAAATTGGAAACTTTGGAAACTCAGGAAATTGCTCTGACAATGTTTTAACTGCTCTCAATTTAAGAAAATGACGAAATGTATAAAAAAG ACAAAAATAACGTGTGCTGTTTTTTCCAAGTGCTTTTTCTAAGTGCTTTTCCATTGTGCAATGAGGTGAAGTTTGGTAATTTTTCGGTGT AGTAGTTAAATATTGCTCAATTTTTATTTACATGTAAAGAAAACAGATTTAAATGTTTATGTGGCCAAAAGGTGTCATTTAAAAGGTAAA ATAAGTTTATGTAGAATGTATGTTCATGGTGCTTATTTTTAAAATGTAATTCAAGTTTACAGTATTACTTAATGCTTCTTTACAGAATTT AATAGAGAAACAAGGCTAGAACACATCTACATCCTGAAGAGCCGTTTATAACTTCATATTATATGATGACAAAGTTCATTATTTTCCTTA AAGTTGAGCAATTGACTTTTATGGTCCAATGATGAACTTATTATTAATAAATGATTGAGTTAACTGTGAGGCTTCTCATTAAAATACAAT ATTGCAGCTATCAGTTGGAGAATATATTATAAAATTTTCAGACAGTATATCAGAAAAATGTTTTTATTTGTACTGTATAGAAAATGTAAT TTTGCTGTTAACTCTGTACTTTTTAAATTGAAAATGTTTTATAAATTTGCTTTTAAATTTTCTTATGAAGCCATTTGCAAATTACATACT >In-frame_NCAPG2_ENST00000449727_chr7_158494513_-_N4BP2_ENST00000261435_chr4_40154400_+_4398nt GAATCTGGTCCGAGCGCGGGAAACGGCGGGTCCCCGAGCCCAGTACCAGACCTCCTGTGCGAAGAGTAACCTGCTCTTCGGACTGATAAC TGGATGGGTTACAAAATAAATGCCATTTGAACAGTGCCATCTGTCATGGAAAAACGTGAGACGTTTGTACAAGCCGTGTCTAAGGAGCTG GTTGGAGAGTTTTTGCAATTTGTTCAACTTGATAATTTAAGCAGAACGGTGGGAAGCCCTATTTGTCTGTGATTACGGGGAGAGGAAACC ACAGCCAGGGAGGAGTTGCTCGCATCAAACCAGCTGTCATTAAGTACCTCATAAGCCATAGCTTCAGGTTCTCTGAAATTAAACCAGGGT GCTTGAAAGTCATGCTAAAGTAAAATAAACATCCTTGAATTAGAAGTATGAAGGTTTGTAGGTTAAAATTACTTTTATTTGCAGTAATTC AGTCAATTCTACCCTAAAGATGTGTTTTATTATAAATAATATTCAATTATGAAACAAAAAAATTATGATGTTTTTCAAAATGCAAGTGAG GTTTGATTTTTTACTGAATCAAATGCAAATGTTACCTGTTAAAGATATTACAGAGAAATTTTATTGATTACAAAATATGTAAGAAAATTA TCAGCTACAGTTTTAAAGTTTAAAATGCTCTGATTGTTTCTCAGAAAAGGTTACCTTTGTATTAATTGTTGTATGACATTTAGTAATGTC CTAAAAGTCTTTTGTGAGAGGTATTTAAAGTGCTTTGAGACCTGATTCATGCCCCCCAAAGGGTGGTATTAAAAGAGGAAAAAGGACATA GTAGTGGTAGTAAAGAAAAAAAGGAGATCTAACAAAAACACTTGAATATTTTTTATTTTCAAAACTAAACACATAAAATGCTTTTATTTT GCCATATCCTACAGGAAGGAAGACATGCTTTTGCCCTTTCTTCTGCTTTGTATATGACCTTGATCTTTTACCTTTTGTTCTGTTCTTCTG TGTGCATTTTATGGAAAGAAAGTTGGGTCTGAGATTATATTGTAATTTTATACTTTCTATAGACAGAAAGGTTTTCAGAGAAAAAGAAAT GGTTAAATATCTTCCAGATGTTGCTGCCTTATCGAAATGCTTCTAGAACTGTCTGTATAAGTCGTATTTCAGACAGTACTAAATACTTAT ATTTTATTTTTGAGGCATGTAATTTTAAAACTGCAGTAGGTTAAAATTCTATTAAACAAATATAGAAAATATTTTGTTTATAATTGGCCT GGTGTGGTGGCCCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTAGGTGGATCGCCTGAGGTCAGAAGTTCAAGACCAGCCTGGCC AACATGGTGAATCCCCGTCTCTATTAAAAATACAAAAATTAGCTGGGTGTGGTGGCGTGTGCCTGTAATCCCAGCTACTTGGGAGGCTGA GGCAGGAGAACCGCTTAAACCTGGGAGGTGGAGGTTGCAGTGACCCGAGATCGAGATCACACCACTGCACTCAGCCTGGGTGACAGAGCA AGACTCCGTCTCCAAAAAAAAAAAAGAAAAAAAAGAGAAAATATTTTGGTTATAATCATAAGAAGAATCCTTACAATTTAAAATATTTTC ACTTTTATTTTGAAAAAGAGCCAACTTTCTCAAAGGAAGCTGTCATTAACTTCTGTTGTTTGGTTAGCTAATAAATTCTGTTAGTATGCA AGTTAAACCTGTGTAAAGGAGGTTATAATGTGGTAAGGTATAATTTTCCAATATGAGACAATGGCTTAAATTTGCCTTTGGAGATGGAGA ATATTTTCAACATACATAATTTTAACAAATAGTTTTGTTGCTTTTTGTTAAGCTTAAAAAAAAATTTGGATCAGAAATTATAGGATTGAG CTGGTACCAAAAGAATCCTAAAGTACAGAATGGTTTTCCAAAAGAGCAGACATTTCAATGAAAATAAAACCCCAAAACATTTTTTTTATA TATCATGATTGCATGCTTTTAAAATAAGGAGGCTTATCATTGAATTTTAGTTCCATAAAAATGAAAATACATGTTTATTATTTAGAAATG GTTAGTGACTGGTATTGAAGTATTATTCACACTTATGTTTGTAATAATTTATTTAAAGAATGCCAACAGTTTAGCACACTTTTGTAATCT CTAGAACAGTTCTATACATTAAAAATAAACATTAAAAATAAAGCAGTTCCTTTAAACAACTTACTATGAAACTATAATTGTTAATGAAAT AAGATATTCCTATGTATACATTAGTATGATTTAAGGGTATGAAAAACAGTGCTAAAATGTGGAGTTAATTGGAATGTGTGCAGCTGCATA CTCACTTTCTGTGTTTTTATATTTCCTTACCTAGTTTTAAAAATCATCACTTTTCGGCACTTCAGCTAGACTTATTTCAATATTATAATT ATGATTAATGAAGGAGCAGTCAGAAGTAGAGGTGTGGTATTCCGTGGGCAGAAGTCAAATGAAAAAAGCTATATTGTTTACTTGTTTACT ATATCAATGTTAATATTATGCCTTATTTTGATAAATCAAATAGTATATCTTAATCATTGTTGATAAATATACAGGCAAAGTTTGAGCATC ATATGTATTTTTATGAAGCTGCTTAATTCCAAATTGCCTCCCACCCCACTATCTAGCATAGTTTAAGCAACACATAATTTTGAAAGAAAA GTTTGTAATCCCTCCTTTCTTTTTTTTGCCCATTTCTAAATCCTGTATGCCCGCAGTAAAGATAGTTTGGGGATTTTAAAAGTTTTCTCT ATTACCCATTTCTAAATCCTGTATGTCAAAGATAGTTTGGAGATTATAAAAATTTTCATGTATTGGTGTAGGTTGAGTATCCCTAATGAG AAAATTCAAAATCTGAAATGCTTCAAAATCTGAAATTTTTCGAGCACAGACATGATGCTCAAAGGAAATACTCACAGAGCATTTTACATT TGTAGGTTAGCGATACTCAACAAGTAAATATAATGCACATGTTCTAAAATATCCCCCCAAACCCCAGCAATCCAAAACACTTCTGGTCCT AAGCATTTTGAGTAGGGGATACTCACTCAACCTGTATATTTGTGCTAATACATGACTCATTAGAATGATTCTTTGTAAACTTAATATTTT AAAAGTACAGCACTTCTGTAGTATGGAAGGTTTCAGTAATAATTATATTCATTCAGTAGTCTCTTACCATTATCTCCCAGATGGAAAAAG AGGACTAATGTGGAAACCCCAGAGGGTGTCCAGTTGGACCAGGGAGATATTAGACACTTAACAGTATTTTCAGTCTGTCCATCTCTTTAT TCCAATGTGAGAAATGGAAGTGTTTTTTTTTTTACGTTTATTGGCTCTTCATATTTCTCTACATTATTTTTAATGTGCAGTTTCTTCAAT TGGTTAGTATTTCCATACTATTTGCAACTTTATGGCCTTTAAATATAGGACATATTATATAGCAGAAATTTTGACTTTAAATCCTCTTGA GTAGTATATTTTGAGAAGAAAAGCTATACTGCTCTTCTGGATGGTTTCCATCCTTTATTTAGGTCTTTTCTTTTTGAATTCAAGTGTTTT GTATGCTTAGAAAGTAGACATGTATAATATTGAGATCGGTTATTTCTGAGCTGGAAATTGGAAACTTTGGAAACTCAGGAAATTGCTCTG ACAATGTTTTAACTGCTCTCAATTTAAGAAAATGACGAAATGTATAAAAAAGACAAAAATAACGTGTGCTGTTTTTTCCAAGTGCTTTTT CTAAGTGCTTTTCCATTGTGCAATGAGGTGAAGTTTGGTAATTTTTCGGTGTAGTAGTTAAATATTGCTCAATTTTTATTTACATGTAAA GAAAACAGATTTAAATGTTTATGTGGCCAAAAGGTGTCATTTAAAAGGTAAAATAAGTTTATGTAGAATGTATGTTCATGGTGCTTATTT TTAAAATGTAATTCAAGTTTACAGTATTACTTAATGCTTCTTTACAGAATTTAATAGAGAAACAAGGCTAGAACACATCTACATCCTGAA GAGCCGTTTATAACTTCATATTATATGATGACAAAGTTCATTATTTTCCTTAAAGTTGAGCAATTGACTTTTATGGTCCAATGATGAACT TATTATTAATAAATGATTGAGTTAACTGTGAGGCTTCTCATTAAAATACAATATTGCAGCTATCAGTTGGAGAATATATTATAAAATTTT CAGACAGTATATCAGAAAAATGTTTTTATTTGTACTGTATAGAAAATGTAATTTTGCTGTTAACTCTGTACTTTTTAAATTGAAAATGTT |
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FusionGenePPI for NCAPG2_N4BP2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NCAPG2 | TAL1, NCAPH2, SMC2, NCAPD3, EGFR, FUS, RIC3, NTRK1, ACTN4, CLTB, SSU72, ESR1, EPHA1, RAF1, CCP110, UHRF2 | N4BP2 | CREBBP, BCL3, EP300, KDM6A, TP63, TP73, TOLLIP, N4BP2, CEP250, RPGRIP1L, FAM98A, FAM136A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NCAPG2_N4BP2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NCAPG2_N4BP2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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