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Fusion gene ID: 23518 |
FusionGeneSummary for NBPF14_ANKRD10 |
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Fusion gene information | Fusion gene name: NBPF14_ANKRD10 | Fusion gene ID: 23518 | Hgene | Tgene | Gene symbol | NBPF14 | ANKRD10 | Gene ID | 25832 | 55608 |
Gene name | NBPF member 14 | ankyrin repeat domain 10 | |
Synonyms | DJ328E19.C1.1|NBPF | - | |
Cytomap | 1q21.2 | 13q34 | |
Type of gene | protein-coding | protein-coding | |
Description | neuroblastoma breakpoint family member 14AE5 | ankyrin repeat domain-containing protein 10 | |
Modification date | 20180519 | 20180519 | |
UniProtAcc | Q5TI25 | Q9NXR5 | |
Ensembl transtripts involved in fusion gene | ENST00000369219, | ENST00000267339, ENST00000375758, ENST00000489973, ENST00000310847, | |
Fusion gene scores | * DoF score | 4 X 4 X 1=16 | 4 X 4 X 2=32 |
# samples | 4 | 4 | |
** MAII score | log2(4/16*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: NBPF14 [Title/Abstract] AND ANKRD10 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AW860861 | NBPF14 | chr1 | 145112445 | + | ANKRD10 | chr13 | 111548772 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000369219 | ENST00000267339 | NBPF14 | chr1 | 145112445 | + | ANKRD10 | chr13 | 111548772 | + |
intron-intron | ENST00000369219 | ENST00000375758 | NBPF14 | chr1 | 145112445 | + | ANKRD10 | chr13 | 111548772 | + |
intron-intron | ENST00000369219 | ENST00000489973 | NBPF14 | chr1 | 145112445 | + | ANKRD10 | chr13 | 111548772 | + |
intron-intron | ENST00000369219 | ENST00000310847 | NBPF14 | chr1 | 145112445 | + | ANKRD10 | chr13 | 111548772 | + |
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FusionProtFeatures for NBPF14_ANKRD10 |
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Hgene | Tgene |
NBPF14 | ANKRD10 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NBPF14_ANKRD10 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for NBPF14_ANKRD10 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NBPF14_ANKRD10 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NBPF14_ANKRD10 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |