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Fusion gene ID: 23449 |
FusionGeneSummary for NAT8L_DBNDD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NAT8L_DBNDD1 | Fusion gene ID: 23449 | Hgene | Tgene | Gene symbol | NAT8L | DBNDD1 | Gene ID | 339983 | 79007 |
| Gene name | N-acetyltransferase 8 like | dysbindin domain containing 1 | |
| Synonyms | CML3|NACED|NAT8-LIKE | - | |
| Cytomap | 4p16.3 | 16q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | N-acetylaspartate synthetaseN-acetyltransferase 8-like (GCN5-related, putative)NAA synthetaseShaticamello-like protein 3 | dysbindin domain-containing protein 1dysbindin (dystrobrevin binding protein 1) domain containing 1 | |
| Modification date | 20180519 | 20180329 | |
| UniProtAcc | Q8N9F0 | Q9H9R9 | |
| Ensembl transtripts involved in fusion gene | ENST00000423729, ENST00000331662, | ENST00000304733, ENST00000002501, ENST00000392973, ENST00000568838, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NAT8L [Title/Abstract] AND DBNDD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | GBM | TCGA-06-0157-01A | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000423729 | ENST00000304733 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| In-frame | ENST00000423729 | ENST00000002501 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| Frame-shift | ENST00000423729 | ENST00000392973 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| In-frame | ENST00000423729 | ENST00000568838 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| In-frame | ENST00000331662 | ENST00000304733 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| In-frame | ENST00000331662 | ENST00000002501 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| Frame-shift | ENST00000331662 | ENST00000392973 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
| In-frame | ENST00000331662 | ENST00000568838 | NAT8L | chr4 | 2062889 | + | DBNDD1 | chr16 | 90075838 | - |
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FusionProtFeatures for NAT8L_DBNDD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NAT8L | DBNDD1 |
| Plays a role in the regulation of lipogenesis byproducing N-acetylaspartate acid (NAA), a brain-specificmetabolite. NAA occurs in high concentration in brain and itshydrolysis plays a significant part in the maintenance of intactwhite matter. Promotes dopamine uptake by regulating TNF-alphaexpression. Attenuates methamphetamine-induced inhibition ofdopamine uptake. {ECO:0000269|PubMed:19524112}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NAT8L | chr4:2062889 | chr16:90075838 | ENST00000423729 | + | 2 | 3 | 40_73 | 180 | 303 | Compositional bias | Note=Pro-rich |
| Hgene | NAT8L | chr4:2062889 | chr16:90075838 | ENST00000423729 | + | 2 | 3 | 121_141 | 180 | 303 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NAT8L | chr4:2062889 | chr16:90075838 | ENST00000331662 | + | 2 | 3 | 40_73 | 12 | 135 | Compositional bias | Note=Pro-rich |
| Hgene | >NAT8L | chr4:2062889 | chr16:90075838 | ENST00000331662 | + | 2 | 3 | 143_283 | 12 | 135 | Domain | N-acetyltransferase |
| Hgene | >NAT8L | chr4:2062889 | chr16:90075838 | ENST00000423729 | + | 2 | 3 | 143_283 | 180 | 303 | Domain | N-acetyltransferase |
| Hgene | >NAT8L | chr4:2062889 | chr16:90075838 | ENST00000331662 | + | 2 | 3 | 121_141 | 12 | 135 | Transmembrane | Helical |
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FusionGeneSequence for NAT8L_DBNDD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_329aa MHCGPPDMVCETKIVAAEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPAPPPAPVAQPHGGAGGAGPPGGRGVCIREFRAAEQEA ARRIFYDGIMERIPNTAFRGLRQHPRAQLLYALLAALCFAVSRSLLLTCLVPAALLGLRYYYSRKVIRAYLECALHTDMADIEQYYMKPP EIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENL >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_329aa MHCGPPDMVCETKIVAAEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPAPPPAPVAQPHGGAGGAGPPGGRGVCIREFRAAEQEA ARRIFYDGIMERIPNTAFRGLRQHPRAQLLYALLAALCFAVSRSLLLTCLVPAALLGLRYYYSRKVIRAYLECALHTDMADIEQYYMKPP EIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENL >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_329aa MHCGPPDMVCETKIVAAEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPAPPPAPVAQPHGGAGGAGPPGGRGVCIREFRAAEQEA ARRIFYDGIMERIPNTAFRGLRQHPRAQLLYALLAALCFAVSRSLLLTCLVPAALLGLRYYYSRKVIRAYLECALHTDMADIEQYYMKPP EIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENL >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_161aa MADIEQYYMKPPEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQEL >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_161aa MADIEQYYMKPPEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQEL >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_161aa MADIEQYYMKPPEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQEL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_987nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_987nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_987nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_483nt ATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAG GGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGG AGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTG GCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGC TCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACG >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_483nt ATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAG GGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGG AGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTG GCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGC TCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACG >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_483nt ATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAG GGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGG AGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTG GCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGC TCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_2457nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC CACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACC ATCTCCACCTGCCCCAGCTCCTGCAGGGATGGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGC CCACGAGGCTCCAGCCGTCACCTCCTGACACACACCCTGGGGGCAGCTCTCTGCCAGCCCCGAGACCGGCCTTGTCTGCTGGGCACGGGT CTTCGCCTCACTTGGAGACCAGCCGGCTTTCCTGGGGGACACACGGGGCCCCCGGATGCCTCTGGGAGCCCCAGCACAAGCACAGCCCAG TGGCCTTACGTCCAGCTCGTTCCTGGGCCCCGAGTCAGGAAGACAGCGTCACGGAGTCACTGCCAGGAACGTGCTGAGGAATGGAGTGGC CCACGGCGGCCTTGGGGTGAAGGGGACCCAGGCCTGTGACAGCCACTCCAGGAACTCCTGGGGGTGCTCCAACCTCCGCGTTTTCCTGTG CTGCCAAGCTCAGAAGCCAGAGGCGGGTTTGGTAGTGGCTAATGGGACAATGTGCTGTCCAGCAAAGCACACATGGAGAAGCGGCCCCAA AATTCCCACCTTGATTTCCATCCTGCCCCTTCTTCTACTCCACGGAGGCGCTGTCTCACTAGGGTCCCCTCCCCAAGGCTCAGCTCTAAG ACCTGCACCTGCTTCTCTTGGCCCCTGCGTGACAGACAAGTCCATTCCCTCCTTAGCTCAGAACACCAAATATCACCAGACTGCCTAAGA GACTTGATGACACCTCCCGGAATGCTCTCGGGGTGGGGTTCACCTCTCCTTGTCCTGCACCCACTGCTAGGCCACATTCTCGTTTCTGCT CACATCCCATTGCCCGGCTACAAGGCCTGCCCACGGCCCTTAAACTTGCTGGGCAGGTTTGGAGCCCATGGGACCCCGTGGGTCTCTGTC CAGGAGCAGCAGAGGAGGCTGACAGGCCCTGCTCCCTCTGCTCTGGGGGTGTCTGGGAGCCCCAGCTCACACCCTCCCAATGCTTATATG CTGAAGCTCACAGAATGGGCTTCTTGCCTGACAGCAAGTCAAAGAATGAGTTTAATATCAAAGTGTAAGCTTACTTTCCATCCCCAAGCC AGCCTGCCCCCTGCCCCATTTCCCATGAGCACACTTCTGGGGAAGGAAAACAGGCTCCTGGCCTTCACTCTCAGCAGAGCTTTGGAGATG CCCCAGGCATGCCCTGAGCTCCTTCTGTGTACCTGCTCCCACTTCTGAGCCACCCGCTGCCCCTCCGCACTGCTGGCAAACCCAGTTCCT GCCTCAGCCAGGTCTCCTTCCCTGGTTTCCAGTCACACAGAGCCCAGCAGCTTTCTCTTTCAGTCCCATAAGGGCAGCCTTGTGTCCCTG GCCACACTTCCACCCGCCAGGGTCTTCCTCCCCATCTTTCCATCCTTCCTGCTGAGCTTCCACAGAGCTCGTTTGCAAACAGGGGGATTA >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_2457nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC CACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACC ATCTCCACCTGCCCCAGCTCCTGCAGGGATGGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGC CCACGAGGCTCCAGCCGTCACCTCCTGACACACACCCTGGGGGCAGCTCTCTGCCAGCCCCGAGACCGGCCTTGTCTGCTGGGCACGGGT CTTCGCCTCACTTGGAGACCAGCCGGCTTTCCTGGGGGACACACGGGGCCCCCGGATGCCTCTGGGAGCCCCAGCACAAGCACAGCCCAG TGGCCTTACGTCCAGCTCGTTCCTGGGCCCCGAGTCAGGAAGACAGCGTCACGGAGTCACTGCCAGGAACGTGCTGAGGAATGGAGTGGC CCACGGCGGCCTTGGGGTGAAGGGGACCCAGGCCTGTGACAGCCACTCCAGGAACTCCTGGGGGTGCTCCAACCTCCGCGTTTTCCTGTG CTGCCAAGCTCAGAAGCCAGAGGCGGGTTTGGTAGTGGCTAATGGGACAATGTGCTGTCCAGCAAAGCACACATGGAGAAGCGGCCCCAA AATTCCCACCTTGATTTCCATCCTGCCCCTTCTTCTACTCCACGGAGGCGCTGTCTCACTAGGGTCCCCTCCCCAAGGCTCAGCTCTAAG ACCTGCACCTGCTTCTCTTGGCCCCTGCGTGACAGACAAGTCCATTCCCTCCTTAGCTCAGAACACCAAATATCACCAGACTGCCTAAGA GACTTGATGACACCTCCCGGAATGCTCTCGGGGTGGGGTTCACCTCTCCTTGTCCTGCACCCACTGCTAGGCCACATTCTCGTTTCTGCT CACATCCCATTGCCCGGCTACAAGGCCTGCCCACGGCCCTTAAACTTGCTGGGCAGGTTTGGAGCCCATGGGACCCCGTGGGTCTCTGTC CAGGAGCAGCAGAGGAGGCTGACAGGCCCTGCTCCCTCTGCTCTGGGGGTGTCTGGGAGCCCCAGCTCACACCCTCCCAATGCTTATATG CTGAAGCTCACAGAATGGGCTTCTTGCCTGACAGCAAGTCAAAGAATGAGTTTAATATCAAAGTGTAAGCTTACTTTCCATCCCCAAGCC AGCCTGCCCCCTGCCCCATTTCCCATGAGCACACTTCTGGGGAAGGAAAACAGGCTCCTGGCCTTCACTCTCAGCAGAGCTTTGGAGATG CCCCAGGCATGCCCTGAGCTCCTTCTGTGTACCTGCTCCCACTTCTGAGCCACCCGCTGCCCCTCCGCACTGCTGGCAAACCCAGTTCCT GCCTCAGCCAGGTCTCCTTCCCTGGTTTCCAGTCACACAGAGCCCAGCAGCTTTCTCTTTCAGTCCCATAAGGGCAGCCTTGTGTCCCTG GCCACACTTCCACCCGCCAGGGTCTTCCTCCCCATCTTTCCATCCTTCCTGCTGAGCTTCCACAGAGCTCGTTTGCAAACAGGGGGATTA >In-frame_NAT8L_ENST00000423729_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_1133nt ATGCATTGTGGGCCTCCCGACATGGTCTGCGAGACGAAGATCGTGGCCGCCGAGGACCATGAGGCGCTGCCGGGGGCCAAGAAGGACGCG CTGCTCGCCGCCGCCGGCGCCATGTGGCCCCCGCTGCCCGCCGCGCCCGGGCCGGCCGCCGCGCCCCCCGCGCCCCCACCTGCCCCGGTG GCTCAGCCTCACGGCGGGGCGGGGGGCGCGGGGCCGCCGGGGGGGCGCGGCGTGTGCATCCGCGAGTTCCGTGCGGCCGAGCAGGAGGCG GCGCGCCGCATCTTCTACGACGGCATCATGGAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTC TACGCCCTGCTGGCGGCGCTGTGCTTCGCCGTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTAC TACTACAGCCGCAAGGTGATCCGCGCCTACCTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCC GAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAG GAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTC CACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTC AACACCGAGTCCCCAGCAGGTCTGCACCCGCTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGC CACGAGAAGCAGCCCCTAGGCGACCCCGAGCGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACC ATCTCCACCTGCCCCAGCTCCTGCAGGGATGGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGC >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000304733_chr16_90075838_-_2157nt GAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTCTACGCCCTGCTGGCGGCGCTGTGCTTCGCC GTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTACTACTACAGCCGCAAGGTGATCCGCGCCTAC CTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAG GCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCG GGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTC ACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCG CTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAG CGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACCATCTCCACCTGCCCCAGCTCCTGCAGGGAT GGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGCCCACGAGGCTCCAGCCGTCACCTCCTGACA CACACCCTGGGGGCAGCTCTCTGCCAGCCCCGAGACCGGCCTTGTCTGCTGGGCACGGGTCTTCGCCTCACTTGGAGACCAGCCGGCTTT CCTGGGGGACACACGGGGCCCCCGGATGCCTCTGGGAGCCCCAGCACAAGCACAGCCCAGTGGCCTTACGTCCAGCTCGTTCCTGGGCCC CGAGTCAGGAAGACAGCGTCACGGAGTCACTGCCAGGAACGTGCTGAGGAATGGAGTGGCCCACGGCGGCCTTGGGGTGAAGGGGACCCA GGCCTGTGACAGCCACTCCAGGAACTCCTGGGGGTGCTCCAACCTCCGCGTTTTCCTGTGCTGCCAAGCTCAGAAGCCAGAGGCGGGTTT GGTAGTGGCTAATGGGACAATGTGCTGTCCAGCAAAGCACACATGGAGAAGCGGCCCCAAAATTCCCACCTTGATTTCCATCCTGCCCCT TCTTCTACTCCACGGAGGCGCTGTCTCACTAGGGTCCCCTCCCCAAGGCTCAGCTCTAAGACCTGCACCTGCTTCTCTTGGCCCCTGCGT GACAGACAAGTCCATTCCCTCCTTAGCTCAGAACACCAAATATCACCAGACTGCCTAAGAGACTTGATGACACCTCCCGGAATGCTCTCG GGGTGGGGTTCACCTCTCCTTGTCCTGCACCCACTGCTAGGCCACATTCTCGTTTCTGCTCACATCCCATTGCCCGGCTACAAGGCCTGC CCACGGCCCTTAAACTTGCTGGGCAGGTTTGGAGCCCATGGGACCCCGTGGGTCTCTGTCCAGGAGCAGCAGAGGAGGCTGACAGGCCCT GCTCCCTCTGCTCTGGGGGTGTCTGGGAGCCCCAGCTCACACCCTCCCAATGCTTATATGCTGAAGCTCACAGAATGGGCTTCTTGCCTG ACAGCAAGTCAAAGAATGAGTTTAATATCAAAGTGTAAGCTTACTTTCCATCCCCAAGCCAGCCTGCCCCCTGCCCCATTTCCCATGAGC ACACTTCTGGGGAAGGAAAACAGGCTCCTGGCCTTCACTCTCAGCAGAGCTTTGGAGATGCCCCAGGCATGCCCTGAGCTCCTTCTGTGT ACCTGCTCCCACTTCTGAGCCACCCGCTGCCCCTCCGCACTGCTGGCAAACCCAGTTCCTGCCTCAGCCAGGTCTCCTTCCCTGGTTTCC AGTCACACAGAGCCCAGCAGCTTTCTCTTTCAGTCCCATAAGGGCAGCCTTGTGTCCCTGGCCACACTTCCACCCGCCAGGGTCTTCCTC >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000002501_chr16_90075838_-_2157nt GAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTCTACGCCCTGCTGGCGGCGCTGTGCTTCGCC GTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTACTACTACAGCCGCAAGGTGATCCGCGCCTAC CTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAG GCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCG GGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTC ACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCG CTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAG CGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACCATCTCCACCTGCCCCAGCTCCTGCAGGGAT GGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGCCCACGAGGCTCCAGCCGTCACCTCCTGACA CACACCCTGGGGGCAGCTCTCTGCCAGCCCCGAGACCGGCCTTGTCTGCTGGGCACGGGTCTTCGCCTCACTTGGAGACCAGCCGGCTTT CCTGGGGGACACACGGGGCCCCCGGATGCCTCTGGGAGCCCCAGCACAAGCACAGCCCAGTGGCCTTACGTCCAGCTCGTTCCTGGGCCC CGAGTCAGGAAGACAGCGTCACGGAGTCACTGCCAGGAACGTGCTGAGGAATGGAGTGGCCCACGGCGGCCTTGGGGTGAAGGGGACCCA GGCCTGTGACAGCCACTCCAGGAACTCCTGGGGGTGCTCCAACCTCCGCGTTTTCCTGTGCTGCCAAGCTCAGAAGCCAGAGGCGGGTTT GGTAGTGGCTAATGGGACAATGTGCTGTCCAGCAAAGCACACATGGAGAAGCGGCCCCAAAATTCCCACCTTGATTTCCATCCTGCCCCT TCTTCTACTCCACGGAGGCGCTGTCTCACTAGGGTCCCCTCCCCAAGGCTCAGCTCTAAGACCTGCACCTGCTTCTCTTGGCCCCTGCGT GACAGACAAGTCCATTCCCTCCTTAGCTCAGAACACCAAATATCACCAGACTGCCTAAGAGACTTGATGACACCTCCCGGAATGCTCTCG GGGTGGGGTTCACCTCTCCTTGTCCTGCACCCACTGCTAGGCCACATTCTCGTTTCTGCTCACATCCCATTGCCCGGCTACAAGGCCTGC CCACGGCCCTTAAACTTGCTGGGCAGGTTTGGAGCCCATGGGACCCCGTGGGTCTCTGTCCAGGAGCAGCAGAGGAGGCTGACAGGCCCT GCTCCCTCTGCTCTGGGGGTGTCTGGGAGCCCCAGCTCACACCCTCCCAATGCTTATATGCTGAAGCTCACAGAATGGGCTTCTTGCCTG ACAGCAAGTCAAAGAATGAGTTTAATATCAAAGTGTAAGCTTACTTTCCATCCCCAAGCCAGCCTGCCCCCTGCCCCATTTCCCATGAGC ACACTTCTGGGGAAGGAAAACAGGCTCCTGGCCTTCACTCTCAGCAGAGCTTTGGAGATGCCCCAGGCATGCCCTGAGCTCCTTCTGTGT ACCTGCTCCCACTTCTGAGCCACCCGCTGCCCCTCCGCACTGCTGGCAAACCCAGTTCCTGCCTCAGCCAGGTCTCCTTCCCTGGTTTCC AGTCACACAGAGCCCAGCAGCTTTCTCTTTCAGTCCCATAAGGGCAGCCTTGTGTCCCTGGCCACACTTCCACCCGCCAGGGTCTTCCTC >In-frame_NAT8L_ENST00000331662_chr4_2062889_+_DBNDD1_ENST00000568838_chr16_90075838_-_833nt GAGCGCATCCCTAACACGGCCTTCCGCGGCCTGCGGCAGCACCCGCGCGCGCAGCTGCTCTACGCCCTGCTGGCGGCGCTGTGCTTCGCC GTGAGCCGCTCGCTGCTGCTGACGTGCCTGGTGCCGGCCGCGCTGCTGGGCCTGCGCTACTACTACAGCCGCAAGGTGATCCGCGCCTAC CTGGAGTGCGCGCTGCACACGGACATGGCGGACATCGAGCAGTACTACATGAAGCCGCCCGAGATCGTTAAGGAGGCTGAGGTGCCGCAG GCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCG GGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTC ACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGGTCTGCACCCG CTGCCCCGGGCCGGCTACCTGCGCTCCCCTTCCTGGACGAGGACAAGGGCTGAGCAGAGCCACGAGAAGCAGCCCCTAGGCGACCCCGAG CGGCAGGCCACAGTCCTGGACACGTTTCTCACTGTGGAGAGGCCCCAGGAGGACTAGACCATCTCCACCTGCCCCAGCTCCTGCAGGGAT GGGGTCCGAACACGATGGCAGATCTGGGCAGTGCTGACCCAGCAGACACACTTCACCCGCCCACGAGGCTCCAGCCGTCACCTCCTGACA |
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FusionGenePPI for NAT8L_DBNDD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NAT8L | TSPAN5, FLNC, KIAA0232, FAT3 | DBNDD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NAT8L_DBNDD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NAT8L_DBNDD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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