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Fusion gene ID: 23362 |
FusionGeneSummary for NADSYN1_PPP6R3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NADSYN1_PPP6R3 | Fusion gene ID: 23362 | Hgene | Tgene | Gene symbol | NADSYN1 | PPP6R3 | Gene ID | 55191 | 55291 |
| Gene name | NAD synthetase 1 | protein phosphatase 6 regulatory subunit 3 | |
| Synonyms | - | C11orf23|PP6R3|SAP190|SAPL|SAPLa|SAPS3 | |
| Cytomap | 11q13.4 | 11q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | glutamine-dependent NAD(+) synthetaseNAD(+) synthaseNAD(+) synthetaseglutamine-dependent NAD synthetase | serine/threonine-protein phosphatase 6 regulatory subunit 3SAPS domain family, member 3sporulation-induced transcript 4-associated protein SAPL | |
| Modification date | 20180523 | 20180520 | |
| UniProtAcc | Q6IA69 | Q5H9R7 | |
| Ensembl transtripts involved in fusion gene | ENST00000319023, ENST00000539574, ENST00000530055, ENST00000526039, | ENST00000393799, ENST00000530427, ENST00000393800, ENST00000534534, ENST00000524845, ENST00000265637, ENST00000524904, ENST00000393801, ENST00000265636, ENST00000529710, ENST00000527403, | |
| Fusion gene scores | * DoF score | 13 X 12 X 8=1248 | 15 X 15 X 6=1350 |
| # samples | 18 | 19 | |
| ** MAII score | log2(18/1248*10)=-2.79354912253257 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(19/1350*10)=-2.82888808360725 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NADSYN1 [Title/Abstract] AND PPP6R3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PPP6R3 | GO:0043666 | regulation of phosphoprotein phosphatase activity | 16716191 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-D9-A3Z3-06A | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000319023 | ENST00000393799 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000530427 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000393800 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000534534 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000524845 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000265637 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000524904 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000393801 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000265636 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000529710 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000319023 | ENST00000527403 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| In-frame | ENST00000539574 | ENST00000393799 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000530427 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000393800 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000534534 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000524845 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000265637 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000524904 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000393801 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000265636 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000529710 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| 5CDS-intron | ENST00000539574 | ENST00000527403 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-3CDS | ENST00000530055 | ENST00000393799 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000530427 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000393800 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000534534 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000524845 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000265637 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000524904 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000393801 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000265636 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000529710 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000530055 | ENST00000527403 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-3CDS | ENST00000526039 | ENST00000393799 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000530427 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000393800 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000534534 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000524845 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000265637 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000524904 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000393801 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000265636 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000529710 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
| intron-intron | ENST00000526039 | ENST00000527403 | NADSYN1 | chr11 | 71189515 | + | PPP6R3 | chr11 | 68321613 | + |
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FusionProtFeatures for NADSYN1_PPP6R3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NADSYN1 | PPP6R3 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NADSYN1 | chr11:71189515 | chr11:68321613 | ENST00000319023 | + | 10 | 21 | 5_275 | 291 | 707 | Domain | CN hydrolase |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NADSYN1 | chr11:71189515 | chr11:68321613 | ENST00000319023 | + | 10 | 21 | 355_362 | 291 | 707 | Nucleotide binding | ATP |
| Hgene | >NADSYN1 | chr11:71189515 | chr11:68321613 | ENST00000319023 | + | 10 | 21 | 325_706 | 291 | 707 | Region | Ligase |
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FusionGeneSequence for NADSYN1_PPP6R3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NADSYN1_ENST00000319023_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_965aa MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHTYESDTLLHSFQVLAALVESPVTQDIICDVGMPV MHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT PHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLT ATLDLEDVRSYRAEISSRNLARHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTL LETRRPTFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTSSINGD LMELNSIGVILNMFFKTTWNNFLHTQVEICIALILASPFENTENATITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRH GYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDSSLQQA FSDTQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQ RRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSE FTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLTVDAKTETAVF >In-frame_NADSYN1_ENST00000539574_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_705aa MGISGQEVLTATLDLEDVRSYRAEISSRNLARHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLATLEKQEIIEQLLSNIFHKEKNESAI VSAIQILLTLLETRRPTFEGHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLL QTNTSSINGDLMELNSIGVILNMFFKTTWNNFLHTQVEICIALILASPFENTENATITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNE KKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETG FSQDSSLQQAFSDTQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEE KHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPT KETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKETLSLT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NADSYN1_ENST00000319023_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_2895nt ATGGGCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTTGCAAAGAATTTTAAAGAGTATT GAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCAGAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATTACGAGTCG GACACCCTCTTGCACTCGTTTCAAGTCCTAGCGGCCCTTGTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGGGATGCCTGTA ATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGGCCAATGAA GGCAACTACCGCGAGCTGCGCTGGTTCACCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATACAGGACCTG ACAAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGTGAGATCTGTGAGGAGCTCTGGACA CCCCACAGCCCGCACATCGACATGGGCCTGGATGGCGTGGAGATCATCACCAACGCCTCGGGCAGCCACCAAGTGCTGCGCAAAGCCAAC ACCAGGGTGGATCTCGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGTGACGGGGACCGCCTG TACTACGACGGCTGTGCCATGATTGCCATGAACGGAAGCGTCTTTGCTCAAGGATCCCAGTTTTCTCTGGATGACGTGGAAGTCCTGACG GCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGCGACATTCAAATGCATCACAATCACTT TGTGAAATTGTTCGCCTGAGCAGAGACCAGATGTTACAAATTCAGAACAGTACAGAGCCCGACCCCCTGCTTGCCACTCTAGAAAAGCAA GAAATTATAGAGCAGCTTCTATCAAATATTTTCCACAAGGAGAAAAATGAGTCAGCCATAGTCAGTGCAATCCAGATATTGCTGACTTTA CTTGAGACACGACGACCAACATTTGAAGGCCATATAGAGATCTGCCCACCAGGCATGAGCCATTCAGCTTGTTCAGTAAACAAGAGTGTT CTAGAAGCCATCAGAGGAAGACTTGGATCTTTTCATGAACTCCTGCTGGAGCCACCCAAGAAAAGTGTGATGAAGACCACATGGGGTGTG CTGGATCCTCCTGTGGGGAATACCCGGTTGAATGTCATTAGGTTGATATCCAGCCTGCTTCAAACCAATACCAGCAGTATAAATGGGGAC CTTATGGAGCTGAATAGCATTGGAGTCATATTGAACATGTTCTTCAAGTATACATGGAATAACTTTTTGCATACACAAGTGGAAATTTGT ATTGCACTGATTCTTGCAAGTCCTTTTGAAAACACAGAAAATGCCACAATTACCGATCAAGACTCCACTGGTGATAATTTGTTATTAAAA CATCTTTTCCAAAAATGTCAATTAATAGAACGAATACTTGAAGCCTGGGAAATGAATGAGAAGAAACAGGCTGAGGGAGGAAGACGGCAT GGTTACATGGGACACCTAACGAGGATAGCTAACTGTATCGTGCACAGCACTGACAAGGGCCCCAACAGTGCATTAGTGCAGCAGCTTATC AAAGATCTTCCCGACGAAGTCAGGGAACGATGGGAGACGTTCTGCACAAGCTCCTTAGGAGAAACTAACAAGAGGAACACGGTAGATCTA GTTACAACCTGCCATATTCATTCATCCAGTGATGATGAAATTGACTTTAAAGAAACGGGTTTCTCACAGGATTCTTCTTTGCAGCAAGCC TTTTCTGATTATCAGATGCAACAAATGACGTCCAATTTTATTGACCAGTTTGGCTTCAACGATGAGAAGTTTGCAGATCAAGATGACATT GGCAATGTTTCTTTTGATCGAGTATCAGACATCAACTTTACTCTCAATACAAATGAAAGTGGAAATATTGCCTTGTTTGAAGCATGTTGT AAGGAAAGAATACAACAGTTTGATGATGGTGGCTCTGATGAGGAAGATATATGGGAGGAAAAGCACATCGCATTCACACCAGAATCCCAA AGACGATCCAGCTCGGGGAGTACAGACAGTGAGGAAAGTACAGACTCTGAAGAAGAAGATGGAGCAAAGCAAGACTTGTTTGAACCCAGC AGTGCCAACACGGAGGATAAAATGGAGGTGGACCTGAGTGAACCACCCAACTGGTCAGCTAACTTTGATGTCCCAATGGAAACAACCCAC GGTGCTCCATTGGATTCTGTGGGATCTGATGTCTGGAGCACAGAGGAGCCGATGCCAACTAAAGAGACGGGCTGGGCTTCTTTTTCAGAG TTCACGTCTTCCCTGAGCACAAAAGATTCTTTAAGGAGTAATTCTCCAGTGGAAATGGAAACCAGCACTGAACCCATGGACCCTCTGACT CCCAGTGCGGCTGCCCTGGCAGTGCAGCCAGAAGCGGCAGGCAGTGTGGCCATGGAAGCCAGCTCTGACGGAGAGGAGGATGCAGAAAGT ACAGACAAGGTAACTGAGACAGTGATGAATGGCGGCATGAAGGAAACGCTCAGCCTCACTGTAGATGCCAAGACAGAGACTGCGGTCTTC AAAAGGTTATTGGGAGGATGCAGTGAGGAAGGGAAACTGTCTACCTCTCAAGATGCTGCTTGTAAAGACGCAGAGGAGTGTCCCGAGACT GCAGAGGCGAAGTGCGCGGCGCCCAGGCCTCCCAGCAGCAGTCCCGAGCAGAGGACTGGCCAACCAAGCGCACCAGGTGACACTTCAGTG >In-frame_NADSYN1_ENST00000539574_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_2115nt ATGGGCATCTCCGGCCAGGAAGTCCTGACGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTG GCGCGACATTCAAATGCATCACAATCACTTTGTGAAATTGTTCGCCTGAGCAGAGACCAGATGTTACAAATTCAGAACAGTACAGAGCCC GACCCCCTGCTTGCCACTCTAGAAAAGCAAGAAATTATAGAGCAGCTTCTATCAAATATTTTCCACAAGGAGAAAAATGAGTCAGCCATA GTCAGTGCAATCCAGATATTGCTGACTTTACTTGAGACACGACGACCAACATTTGAAGGCCATATAGAGATCTGCCCACCAGGCATGAGC CATTCAGCTTGTTCAGTAAACAAGAGTGTTCTAGAAGCCATCAGAGGAAGACTTGGATCTTTTCATGAACTCCTGCTGGAGCCACCCAAG AAAAGTGTGATGAAGACCACATGGGGTGTGCTGGATCCTCCTGTGGGGAATACCCGGTTGAATGTCATTAGGTTGATATCCAGCCTGCTT CAAACCAATACCAGCAGTATAAATGGGGACCTTATGGAGCTGAATAGCATTGGAGTCATATTGAACATGTTCTTCAAGTATACATGGAAT AACTTTTTGCATACACAAGTGGAAATTTGTATTGCACTGATTCTTGCAAGTCCTTTTGAAAACACAGAAAATGCCACAATTACCGATCAA GACTCCACTGGTGATAATTTGTTATTAAAACATCTTTTCCAAAAATGTCAATTAATAGAACGAATACTTGAAGCCTGGGAAATGAATGAG AAGAAACAGGCTGAGGGAGGAAGACGGCATGGTTACATGGGACACCTAACGAGGATAGCTAACTGTATCGTGCACAGCACTGACAAGGGC CCCAACAGTGCATTAGTGCAGCAGCTTATCAAAGATCTTCCCGACGAAGTCAGGGAACGATGGGAGACGTTCTGCACAAGCTCCTTAGGA GAAACTAACAAGAGGAACACGGTAGATCTAGTTACAACCTGCCATATTCATTCATCCAGTGATGATGAAATTGACTTTAAAGAAACGGGT TTCTCACAGGATTCTTCTTTGCAGCAAGCCTTTTCTGATTATCAGATGCAACAAATGACGTCCAATTTTATTGACCAGTTTGGCTTCAAC GATGAGAAGTTTGCAGATCAAGATGACATTGGCAATGTTTCTTTTGATCGAGTATCAGACATCAACTTTACTCTCAATACAAATGAAAGT GGAAATATTGCCTTGTTTGAAGCATGTTGTAAGGAAAGAATACAACAGTTTGATGATGGTGGCTCTGATGAGGAAGATATATGGGAGGAA AAGCACATCGCATTCACACCAGAATCCCAAAGACGATCCAGCTCGGGGAGTACAGACAGTGAGGAAAGTACAGACTCTGAAGAAGAAGAT GGAGCAAAGCAAGACTTGTTTGAACCCAGCAGTGCCAACACGGAGGATAAAATGGAGGTGGACCTGAGTGAACCACCCAACTGGTCAGCT AACTTTGATGTCCCAATGGAAACAACCCACGGTGCTCCATTGGATTCTGTGGGATCTGATGTCTGGAGCACAGAGGAGCCGATGCCAACT AAAGAGACGGGCTGGGCTTCTTTTTCAGAGTTCACGTCTTCCCTGAGCACAAAAGATTCTTTAAGGAGTAATTCTCCAGTGGAAATGGAA ACCAGCACTGAACCCATGGACCCTCTGACTCCCAGTGCGGCTGCCCTGGCAGTGCAGCCAGAAGCGGCAGGCAGTGTGGCCATGGAAGCC AGCTCTGACGGAGAGGAGGATGCAGAAAGTACAGACAAGGTAACTGAGACAGTGATGAATGGCGGCATGAAGGAAACGCTCAGCCTCACT GTAGATGCCAAGACAGAGACTGCGGTCTTCAAAAGGTTATTGGGAGGATGCAGTGAGGAAGGGAAACTGTCTACCTCTCAAGATGCTGCT TGTAAAGACGCAGAGGAGTGTCCCGAGACTGCAGAGGCGAAGTGCGCGGCGCCCAGGCCTCCCAGCAGCAGTCCCGAGCAGAGGACTGGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NADSYN1_ENST00000319023_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_5295nt AGACGGGGCGGGGCGATCCGTAGGCAGGGCCTGACGCCGCAGTCCTCCTTGGCCGGAGCCTCAACGGATGGGCGGGGAGGGGGCGGGGCC GGGCAACCCGGAAGGTCCGGCGTCCCAGCCGCCTACCTCGCTGGGACCCTGGTCTTGCTGTCCCCCGCTGGCCTCCTGCCCAAGCGACTG CGGCCAGGATGGGCCGGAAGGTGACCGTGGCCACCTGCGCACTCAACCAGTGGGCCCTGGACTTCGAGGGCAATTTGCAAAGAATTTTAA AGAGTATTGAAATTGCCAAAAACAGAGGAGCAAGATACAGGCTTGGACCAGAGCTGGAAATATGCGGCTACGGATGTTGGGATCATTATT ACGAGTCGGACACCCTCTTGCACTCGTTTCAAGTCCTAGCGGCCCTTGTGGAGTCTCCCGTCACTCAGGACATCATCTGCGACGTGGGGA TGCCTGTAATGCACCGAAACGTCCGCTACAACTGCAGAGTGATATTCCTCAACAGGAAGATCCTGCTCATCAGACCCAAGATGGCCTTGG CCAATGAAGGCAACTACCGCGAGCTGCGCTGGTTCACCCCGTGGTCGAGGAGTCGGCACACAGAGGAGTACTTTCTGCCTCGGATGATAC AGGACCTGACAAAGCAGGAAACCGTACCCTTCGGAGATGCGGTGCTGGTGACATGGGACACCTGCATTGGAAGTGAGATCTGTGAGGAGC TCTGGACACCCCACAGCCCGCACATCGACATGGGCCTGGATGGCGTGGAGATCATCACCAACGCCTCGGGCAGCCACCAAGTGCTGCGCA AAGCCAACACCAGGGTGGATCTCGTGACTATGGTCACCAGCAAGAACGGTGGGATTTACTTGCTGGCCAACCAGAAGGGTTGTGACGGGG ACCGCCTGTACTACGACGGCTGTGCCATGATTGCCATGAACGGAAGCGTCTTTGCTCAAGGATCCCAGTTTTCTCTGGATGACGTGGAAG TCCTGACGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGCGACATTCAAATGCATCAC AATCACTTTGTGAAATTGTTCGCCTGAGCAGAGACCAGATGTTACAAATTCAGAACAGTACAGAGCCCGACCCCCTGCTTGCCACTCTAG AAAAGCAAGAAATTATAGAGCAGCTTCTATCAAATATTTTCCACAAGGAGAAAAATGAGTCAGCCATAGTCAGTGCAATCCAGATATTGC TGACTTTACTTGAGACACGACGACCAACATTTGAAGGCCATATAGAGATCTGCCCACCAGGCATGAGCCATTCAGCTTGTTCAGTAAACA AGAGTGTTCTAGAAGCCATCAGAGGAAGACTTGGATCTTTTCATGAACTCCTGCTGGAGCCACCCAAGAAAAGTGTGATGAAGACCACAT GGGGTGTGCTGGATCCTCCTGTGGGGAATACCCGGTTGAATGTCATTAGGTTGATATCCAGCCTGCTTCAAACCAATACCAGCAGTATAA ATGGGGACCTTATGGAGCTGAATAGCATTGGAGTCATATTGAACATGTTCTTCAAGTATACATGGAATAACTTTTTGCATACACAAGTGG AAATTTGTATTGCACTGATTCTTGCAAGTCCTTTTGAAAACACAGAAAATGCCACAATTACCGATCAAGACTCCACTGGTGATAATTTGT TATTAAAACATCTTTTCCAAAAATGTCAATTAATAGAACGAATACTTGAAGCCTGGGAAATGAATGAGAAGAAACAGGCTGAGGGAGGAA GACGGCATGGTTACATGGGACACCTAACGAGGATAGCTAACTGTATCGTGCACAGCACTGACAAGGGCCCCAACAGTGCATTAGTGCAGC AGCTTATCAAAGATCTTCCCGACGAAGTCAGGGAACGATGGGAGACGTTCTGCACAAGCTCCTTAGGAGAAACTAACAAGAGGAACACGG TAGATCTAGTTACAACCTGCCATATTCATTCATCCAGTGATGATGAAATTGACTTTAAAGAAACGGGTTTCTCACAGGATTCTTCTTTGC AGCAAGCCTTTTCTGATTATCAGATGCAACAAATGACGTCCAATTTTATTGACCAGTTTGGCTTCAACGATGAGAAGTTTGCAGATCAAG ATGACATTGGCAATGTTTCTTTTGATCGAGTATCAGACATCAACTTTACTCTCAATACAAATGAAAGTGGAAATATTGCCTTGTTTGAAG CATGTTGTAAGGAAAGAATACAACAGTTTGATGATGGTGGCTCTGATGAGGAAGATATATGGGAGGAAAAGCACATCGCATTCACACCAG AATCCCAAAGACGATCCAGCTCGGGGAGTACAGACAGTGAGGAAAGTACAGACTCTGAAGAAGAAGATGGAGCAAAGCAAGACTTGTTTG AACCCAGCAGTGCCAACACGGAGGATAAAATGGAGGTGGACCTGAGTGAACCACCCAACTGGTCAGCTAACTTTGATGTCCCAATGGAAA CAACCCACGGTGCTCCATTGGATTCTGTGGGATCTGATGTCTGGAGCACAGAGGAGCCGATGCCAACTAAAGAGACGGGCTGGGCTTCTT TTTCAGAGTTCACGTCTTCCCTGAGCACAAAAGATTCTTTAAGGAGTAATTCTCCAGTGGAAATGGAAACCAGCACTGAACCCATGGACC CTCTGACTCCCAGTGCGGCTGCCCTGGCAGTGCAGCCAGAAGCGGCAGGCAGTGTGGCCATGGAAGCCAGCTCTGACGGAGAGGAGGATG CAGAAAGTACAGACAAGGTAACTGAGACAGTGATGAATGGCGGCATGAAGGAAACGCTCAGCCTCACTGTAGATGCCAAGACAGAGACTG CGGTCTTCAAAAGGTTATTGGGAGGATGCAGTGAGGAAGGGAAACTGTCTACCTCTCAAGATGCTGCTTGTAAAGACGCAGAGGAGTGTC CCGAGACTGCAGAGGCGAAGTGCGCGGCGCCCAGGCCTCCCAGCAGCAGTCCCGAGCAGAGGACTGGCCAACCAAGCGCACCAGGTGACA CTTCAGTGAATGGCCCTGTATGACGGGTGACGTCTGCTGCTGCTGACTGAGGACTGCAGACCGCCACCACTCAGGGGCTCTGGAGGGGTC AGCTGGAGCCCACCAAGCTGTCACTGCTGCACTCACTCTGCAAGGGATCAGGACCAGCAACCTTTATATTCTAGATTCTAAGACATTGTA CAGAGAAATTCAGAAGTGTAAAAATATTGCACATTGACAAATACCAAGAATTTTTGCGTATGTTTATATTGTATTGTTCTAAATAATGGG TAGCCTGTGAAATAAGATCTTGCCACCCATGTAATAATAGTAGTAATACTATAGTTAAAATGGCTGTAAGAATAGTTTTATAAAAGTGAA TACACAGATCTATTGTATTTGAAACATAACTTTGACAATTATTAGTGTGACCAAAGTATTAGGCGGTTTTCATACATTTTTCACCTTGTA CAAAATTATGAATTCATTTTTCCTCCAGGCCGACAAGGAGTTGTAGAATGAAAATGCCCTCTAAGTGTTATTTTGGTTGTTCTAACTTAC AAAAGTGATTTTGAATAAGAAATATTTGGTGTTCTTTTTATAACCAGTTTTTGATTGGTAATTGTTTTCTGTATTGTTTAAAACGGATCA AAAATGTAAGTCTATTGGTAGAGATTAAGTAAAGTATTTATTGCTACATCATAGTTGATAAATTGATGTTATCGTAAAGCCATATGTTCT GTTCAAGTCTTGTTTGCTTGAAATGATTATTCCTACAAGTGAAACACTAGACTATTTGGAGTGTATATGGCTTGTGTTTTGGGATTTTTT TTTTTTTTTTTTGGCTTTTGTTTTTGTTTGTTTTTTTGTTTCATTTGGTAGTTCATCTGCCTTTTAACCCATTCACCAAAATTTACCTTG TTAACAAGCATCACCAATGAACATTTCAGAGCAATCTGCATATTTAACAGACCTAAAATAAATCCTATTAGGCAAGTCAGTTGAAAATGC TCGTGCTGCTAATGGAATTAGAGTGCGTTCATTTTACAGGCTAGTATTTTAAAAGTAGAAATCAAAATCTGGCACCGAAGCATGCTAATT GTTTACTGTACCTTGTGAGGTTTTCACTCATAAATTTAAACCAGTGTATTTTTTTAGAACTGGTTTGTGTATATATATAGTGATTATGGA TACTAATTCAATGTAATTTATAATTTTCTATGTCAATACAAAAATACATCACAGCCTTCTCAAACAGCTCAAGCAATATATTGTATATTG CCATATCGTCTGGTGAAAGGGTTAAATTACTTCACCTCTTGCACTTTTAGATGCAAATCAGTTTTTCATTTCTGTAATAGAAAATTATTC ACGTATTTTTACATCATTTGTTTTTCCTGACCAGTATTTAAAACCAAAAGGATATTCTGAAAAATGGCCAACAATTTTTTTAGAAGTAGC ATCCCAAGCAGCGTGCCTAAACATTACATTGCATATGGAAATAAAAGAATCAAACGTCTAATGCCTTATTATTTCTGATTTCCTTTTTCA TTTTAAGTGGTGTGGAGATTCCAGCACTCCCAGGACAGTGGAGTCAGCAGTAAGCCCTGGGACAGGTGGCAAGGGTGGGTCCCTTGACCT TTGCACGCCTCCTCAGGAACCCCCTTTCCCGGGTGAGCCCCTCTCTGAAGAGACTGTCCTTGGGCCTCCTCTGGAAGCAGCACCCCCAGA GGACAGGGCTCCTCCTGCTTGCCTCAGGGCTGCCTGACTTGAATGGCGTTGGACCTCGGGGATTACTGGTAGATAATATGCTCTGGTCTC GCCTGGTGGTGAGTTTTGCCAGCCATGGCCAGGGTTTGGCTCCACTGGTGGCACACGTGGCCTCCGTGGTATGGACCTGGTGGCTTCTCC ATCCCACTGTGGCCTCTGTGGTATGGACCTGGTGGCTTCTCCATCCTACCCAAGGTAACAGTGTCTTGCTTCATCCCACTGACTGCTGGG AGAGAGCCTCTGGGACTTTTCTTTGGGGCATCATTTTGTTTTGTCTTTCGTAGCAGGGAAAGGATATGACAATGGGGAGGACAGTTCTTT TGGAGGTTGGAGGGGCCAAGCCAAGGACAGGAGCAAGTGTGCCCTCATTTTGTTTCTACTTTTAATTTCTGTGTGTTGGCCATACTGAAT >In-frame_NADSYN1_ENST00000539574_chr11_71189515_+_PPP6R3_ENST00000393799_chr11_68321613_+_5109nt ATCATTAACCGCGACAGAGCTGGAAGGGCTTTGAAGAGAAGGATTAAGTTCCTGCTGATGGGAAGTGTGGTCCTCTCCCCGTTCACGTCA GAGCCACAGGCACATTGGTGGTCGTGTTGATTGGCAGGTGTGTTGGCAATCAATCACCTGCCCCAGGACCCCCGCAGGTTCCCGGCCCCA CATCAAGCCACCAAATCGGAGTCCTCGGGGGTCTGTATATTTAGTGAGCACCAGGCAGTTGTTTCGTGCATTAGAATCCGGGAGCCGTTG CCTTACACGTCTCTAGAGTTCCTGATGTTGCCTGAGAGCTCCGTCGTAGGCTGTGGCCACAGGCCTGCTGTATTCAGAGTGGCCGCGCTG TCCTCAGGCTCGGGCCACTGCCCTCCACCAGGTCCTCCGTGGTGCACCTGAAATGGTCAACAGAAGTCTTGTGACACGTGGAATCATTTC AGAGTCACCCCTTCTGCCTCCTGCTCAAGCAACAGACCTGCCGATCACCCCCGTCGGGCCCGCGTTTCTCAGGGTCTTCCTAATCCCCTG GGCTTTCCGGCTTGTCGTGTGCCTGGAGTCAGGCCGCCGTGCGGCAGGCTGTTAACCTAGCCTCGGGGAGAGTGGGATGGAGCCACCTTC TCATGGAACGATCCTCGCCTTCCCTCATCTCCATTGTTTTATGGCTTCACACGGACCGTGGCTTTCTGCATGGAAGCTTGGTGGCCAGGG TGCTGTCACTTTGGGAAGCAGCCAGAGAACCACAGGATGCGTGAATCGGTCTCCTTGTCTTCATGGGCATCTCCGGCCAGGAAGTCCTGA CGGCCACGCTGGATCTGGAGGACGTCCGGAGCTACAGGGCGGAGATTTCATCTCGAAACCTGGCGCGACATTCAAATGCATCACAATCAC TTTGTGAAATTGTTCGCCTGAGCAGAGACCAGATGTTACAAATTCAGAACAGTACAGAGCCCGACCCCCTGCTTGCCACTCTAGAAAAGC AAGAAATTATAGAGCAGCTTCTATCAAATATTTTCCACAAGGAGAAAAATGAGTCAGCCATAGTCAGTGCAATCCAGATATTGCTGACTT TACTTGAGACACGACGACCAACATTTGAAGGCCATATAGAGATCTGCCCACCAGGCATGAGCCATTCAGCTTGTTCAGTAAACAAGAGTG TTCTAGAAGCCATCAGAGGAAGACTTGGATCTTTTCATGAACTCCTGCTGGAGCCACCCAAGAAAAGTGTGATGAAGACCACATGGGGTG TGCTGGATCCTCCTGTGGGGAATACCCGGTTGAATGTCATTAGGTTGATATCCAGCCTGCTTCAAACCAATACCAGCAGTATAAATGGGG ACCTTATGGAGCTGAATAGCATTGGAGTCATATTGAACATGTTCTTCAAGTATACATGGAATAACTTTTTGCATACACAAGTGGAAATTT GTATTGCACTGATTCTTGCAAGTCCTTTTGAAAACACAGAAAATGCCACAATTACCGATCAAGACTCCACTGGTGATAATTTGTTATTAA AACATCTTTTCCAAAAATGTCAATTAATAGAACGAATACTTGAAGCCTGGGAAATGAATGAGAAGAAACAGGCTGAGGGAGGAAGACGGC ATGGTTACATGGGACACCTAACGAGGATAGCTAACTGTATCGTGCACAGCACTGACAAGGGCCCCAACAGTGCATTAGTGCAGCAGCTTA TCAAAGATCTTCCCGACGAAGTCAGGGAACGATGGGAGACGTTCTGCACAAGCTCCTTAGGAGAAACTAACAAGAGGAACACGGTAGATC TAGTTACAACCTGCCATATTCATTCATCCAGTGATGATGAAATTGACTTTAAAGAAACGGGTTTCTCACAGGATTCTTCTTTGCAGCAAG CCTTTTCTGATTATCAGATGCAACAAATGACGTCCAATTTTATTGACCAGTTTGGCTTCAACGATGAGAAGTTTGCAGATCAAGATGACA TTGGCAATGTTTCTTTTGATCGAGTATCAGACATCAACTTTACTCTCAATACAAATGAAAGTGGAAATATTGCCTTGTTTGAAGCATGTT GTAAGGAAAGAATACAACAGTTTGATGATGGTGGCTCTGATGAGGAAGATATATGGGAGGAAAAGCACATCGCATTCACACCAGAATCCC AAAGACGATCCAGCTCGGGGAGTACAGACAGTGAGGAAAGTACAGACTCTGAAGAAGAAGATGGAGCAAAGCAAGACTTGTTTGAACCCA GCAGTGCCAACACGGAGGATAAAATGGAGGTGGACCTGAGTGAACCACCCAACTGGTCAGCTAACTTTGATGTCCCAATGGAAACAACCC ACGGTGCTCCATTGGATTCTGTGGGATCTGATGTCTGGAGCACAGAGGAGCCGATGCCAACTAAAGAGACGGGCTGGGCTTCTTTTTCAG AGTTCACGTCTTCCCTGAGCACAAAAGATTCTTTAAGGAGTAATTCTCCAGTGGAAATGGAAACCAGCACTGAACCCATGGACCCTCTGA CTCCCAGTGCGGCTGCCCTGGCAGTGCAGCCAGAAGCGGCAGGCAGTGTGGCCATGGAAGCCAGCTCTGACGGAGAGGAGGATGCAGAAA GTACAGACAAGGTAACTGAGACAGTGATGAATGGCGGCATGAAGGAAACGCTCAGCCTCACTGTAGATGCCAAGACAGAGACTGCGGTCT TCAAAAGGTTATTGGGAGGATGCAGTGAGGAAGGGAAACTGTCTACCTCTCAAGATGCTGCTTGTAAAGACGCAGAGGAGTGTCCCGAGA CTGCAGAGGCGAAGTGCGCGGCGCCCAGGCCTCCCAGCAGCAGTCCCGAGCAGAGGACTGGCCAACCAAGCGCACCAGGTGACACTTCAG TGAATGGCCCTGTATGACGGGTGACGTCTGCTGCTGCTGACTGAGGACTGCAGACCGCCACCACTCAGGGGCTCTGGAGGGGTCAGCTGG AGCCCACCAAGCTGTCACTGCTGCACTCACTCTGCAAGGGATCAGGACCAGCAACCTTTATATTCTAGATTCTAAGACATTGTACAGAGA AATTCAGAAGTGTAAAAATATTGCACATTGACAAATACCAAGAATTTTTGCGTATGTTTATATTGTATTGTTCTAAATAATGGGTAGCCT GTGAAATAAGATCTTGCCACCCATGTAATAATAGTAGTAATACTATAGTTAAAATGGCTGTAAGAATAGTTTTATAAAAGTGAATACACA GATCTATTGTATTTGAAACATAACTTTGACAATTATTAGTGTGACCAAAGTATTAGGCGGTTTTCATACATTTTTCACCTTGTACAAAAT TATGAATTCATTTTTCCTCCAGGCCGACAAGGAGTTGTAGAATGAAAATGCCCTCTAAGTGTTATTTTGGTTGTTCTAACTTACAAAAGT GATTTTGAATAAGAAATATTTGGTGTTCTTTTTATAACCAGTTTTTGATTGGTAATTGTTTTCTGTATTGTTTAAAACGGATCAAAAATG TAAGTCTATTGGTAGAGATTAAGTAAAGTATTTATTGCTACATCATAGTTGATAAATTGATGTTATCGTAAAGCCATATGTTCTGTTCAA GTCTTGTTTGCTTGAAATGATTATTCCTACAAGTGAAACACTAGACTATTTGGAGTGTATATGGCTTGTGTTTTGGGATTTTTTTTTTTT TTTTTTGGCTTTTGTTTTTGTTTGTTTTTTTGTTTCATTTGGTAGTTCATCTGCCTTTTAACCCATTCACCAAAATTTACCTTGTTAACA AGCATCACCAATGAACATTTCAGAGCAATCTGCATATTTAACAGACCTAAAATAAATCCTATTAGGCAAGTCAGTTGAAAATGCTCGTGC TGCTAATGGAATTAGAGTGCGTTCATTTTACAGGCTAGTATTTTAAAAGTAGAAATCAAAATCTGGCACCGAAGCATGCTAATTGTTTAC TGTACCTTGTGAGGTTTTCACTCATAAATTTAAACCAGTGTATTTTTTTAGAACTGGTTTGTGTATATATATAGTGATTATGGATACTAA TTCAATGTAATTTATAATTTTCTATGTCAATACAAAAATACATCACAGCCTTCTCAAACAGCTCAAGCAATATATTGTATATTGCCATAT CGTCTGGTGAAAGGGTTAAATTACTTCACCTCTTGCACTTTTAGATGCAAATCAGTTTTTCATTTCTGTAATAGAAAATTATTCACGTAT TTTTACATCATTTGTTTTTCCTGACCAGTATTTAAAACCAAAAGGATATTCTGAAAAATGGCCAACAATTTTTTTAGAAGTAGCATCCCA AGCAGCGTGCCTAAACATTACATTGCATATGGAAATAAAAGAATCAAACGTCTAATGCCTTATTATTTCTGATTTCCTTTTTCATTTTAA GTGGTGTGGAGATTCCAGCACTCCCAGGACAGTGGAGTCAGCAGTAAGCCCTGGGACAGGTGGCAAGGGTGGGTCCCTTGACCTTTGCAC GCCTCCTCAGGAACCCCCTTTCCCGGGTGAGCCCCTCTCTGAAGAGACTGTCCTTGGGCCTCCTCTGGAAGCAGCACCCCCAGAGGACAG GGCTCCTCCTGCTTGCCTCAGGGCTGCCTGACTTGAATGGCGTTGGACCTCGGGGATTACTGGTAGATAATATGCTCTGGTCTCGCCTGG TGGTGAGTTTTGCCAGCCATGGCCAGGGTTTGGCTCCACTGGTGGCACACGTGGCCTCCGTGGTATGGACCTGGTGGCTTCTCCATCCCA CTGTGGCCTCTGTGGTATGGACCTGGTGGCTTCTCCATCCTACCCAAGGTAACAGTGTCTTGCTTCATCCCACTGACTGCTGGGAGAGAG CCTCTGGGACTTTTCTTTGGGGCATCATTTTGTTTTGTCTTTCGTAGCAGGGAAAGGATATGACAATGGGGAGGACAGTTCTTTTGGAGG TTGGAGGGGCCAAGCCAAGGACAGGAGCAAGTGTGCCCTCATTTTGTTTCTACTTTTAATTTCTGTGTGTTGGCCATACTGAATTATGAG |
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FusionGenePPI for NADSYN1_PPP6R3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NADSYN1 | CUTC, MYO15B, UPF1, AIP, STUB1, EGFR, FKBPL, CSGALNACT2 | PPP6R3 | KDM6A, TNFAIP3, USP21, USP36, USP49, PPP6C, PRKDC, HDAC1, HDAC2, ELAVL1, SIRT7, TERF2IP, TINF2, TFAP4, GRK5, PFAS, BRCA1, ECT2, NOTCH1, LATS1, GPSM1, HDAC11, USP10, ANKRD28, MOB1A, MOB1B, ACAD11, ANKRD44, ANKRD52, AP1B1, AP2A1, AP2A2, AURKA, DNAJC11, ECH1, ERLIN2, PPP6R1, PPP6R2, CDC37, ENAH, ETFA, HSP90AA1, HSP90AB1, RUVBL2, SRRT, TPM1, USP7, CSNK1E, SNAI2, RNF2, GPHA2, RPS6KB2, UNK, DIEXF, NSUN5, EIF4A3, TIPRL, NTRK1, CEP44, CEP19, XPO1, ZNRF2, ZNF746, TRMT2A, TRIM25, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NADSYN1_PPP6R3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | NADSYN1 | Q6IA69 | DB00142 | Glutamic Acid | Glutamine-dependent NAD(+) synthetase | small molecule | approved|nutraceutical |
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RelatedDiseases for NADSYN1_PPP6R3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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