![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 2326 |
FusionGeneSummary for ARF5_ARF5 |
![]() |
Fusion gene information | Fusion gene name: ARF5_ARF5 | Fusion gene ID: 2326 | Hgene | Tgene | Gene symbol | ARF5 | ARF5 | Gene ID | 381 | 381 |
Gene name | ADP ribosylation factor 5 | ADP ribosylation factor 5 | |
Synonyms | - | - | |
Cytomap | 7q32.1 | 7q32.1 | |
Type of gene | protein-coding | protein-coding | |
Description | ADP-ribosylation factor 5 | ADP-ribosylation factor 5 | |
Modification date | 20180526 | 20180526 | |
UniProtAcc | P84085 | P84085 | |
Ensembl transtripts involved in fusion gene | ENST00000000233, ENST00000467281, | ENST00000000233, ENST00000467281, | |
Fusion gene scores | * DoF score | 1 X 2 X 1=2 | 2 X 3 X 2=12 |
# samples | 3 | 4 | |
** MAII score | log2(3/2*10)=3.90689059560852 | log2(4/12*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: ARF5 [Title/Abstract] AND ARF5 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | G30809 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - | ||
ChiTaRS3.1 | AA077782 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - | ||
ChiTaRS3.1 | BF765618 | ARF5 | chr7 | 127230161 | + | ARF5 | chr7 | 127231421 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000000233 | ENST00000000233 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - |
5CDS-intron | ENST00000000233 | ENST00000467281 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - |
3UTR-intron | ENST00000467281 | ENST00000000233 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - |
3UTR-intron | ENST00000467281 | ENST00000467281 | ARF5 | chr7 | 127229181 | + | ARF5 | chr7 | 127229648 | - |
5CDS-3UTR | ENST00000000233 | ENST00000000233 | ARF5 | chr7 | 127230161 | + | ARF5 | chr7 | 127231421 | - |
5CDS-intron | ENST00000000233 | ENST00000467281 | ARF5 | chr7 | 127230161 | + | ARF5 | chr7 | 127231421 | - |
intron-3UTR | ENST00000467281 | ENST00000000233 | ARF5 | chr7 | 127230161 | + | ARF5 | chr7 | 127231421 | - |
intron-intron | ENST00000467281 | ENST00000467281 | ARF5 | chr7 | 127230161 | + | ARF5 | chr7 | 127231421 | - |
Top |
FusionProtFeatures for ARF5_ARF5 |
![]() |
Hgene | Tgene |
ARF5 | ARF5 |
GTP-binding protein that functions as an allostericactivator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulatevesicle budding and uncoating within the Golgi apparatus. | GTP-binding protein that functions as an allostericactivator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulatevesicle budding and uncoating within the Golgi apparatus. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for ARF5_ARF5 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for ARF5_ARF5 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for ARF5_ARF5 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ARF5_ARF5 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |