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Fusion gene ID: 23164 |
FusionGeneSummary for MYO5A_OIP5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MYO5A_OIP5 | Fusion gene ID: 23164 | Hgene | Tgene | Gene symbol | MYO5A | OIP5 | Gene ID | 4644 | 11339 |
| Gene name | myosin VA | Opa interacting protein 5 | |
| Synonyms | GS1|MYH12|MYO5|MYR12 | 5730547N13Rik|CT86|LINT-25|MIS18B|MIS18beta|hMIS18beta | |
| Cytomap | 15q21.2 | 15q15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | unconventional myosin-Vadilute myosin heavy chain, non-musclemyosin Vmyosin VA (heavy chain 12, myoxin)myosin, heavy polypeptide kinasemyosin-12myosin-Vamyoxin | protein Mis18-betaLAP2alpha interactor-25MIS18 kinetochore protein homolog Bcancer/testis antigen 86opa-interacting protein 5 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9Y4I1 | O43482 | |
| Ensembl transtripts involved in fusion gene | ENST00000399231, ENST00000356338, ENST00000358212, ENST00000399233, ENST00000553916, | ENST00000220514, | |
| Fusion gene scores | * DoF score | 8 X 8 X 4=256 | 2 X 2 X 2=8 |
| # samples | 8 | 2 | |
| ** MAII score | log2(8/256*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: MYO5A [Title/Abstract] AND OIP5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-JL-A3YX-01A | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000399231 | ENST00000220514 | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
| In-frame | ENST00000356338 | ENST00000220514 | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
| In-frame | ENST00000358212 | ENST00000220514 | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
| In-frame | ENST00000399233 | ENST00000220514 | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
| In-frame | ENST00000553916 | ENST00000220514 | MYO5A | chr15 | 52689398 | - | OIP5 | chr15 | 41611978 | - |
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FusionProtFeatures for MYO5A_OIP5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MYO5A | OIP5 |
| Processive actin-based motor that can move in largesteps approximating the 36-nm pseudo-repeat of the actin filament.Involved in melanosome transport. Also mediates the transport ofvesicles to the plasma membrane. May also be required for somepolarization process involved in dendrite formation.{ECO:0000269|PubMed:10448864}. | Required for recruitment of CENPA to centromeres andnormal chromosome segregation during mitosis.{ECO:0000269|PubMed:17199038}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 8_60 | 439 | 1829 | Domain | Myosin N-terminal SH3-like |
| Hgene | MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 8_60 | 439 | 1856 | Domain | Myosin N-terminal SH3-like |
| Hgene | MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 163_170 | 439 | 1829 | Nucleotide binding | ATP |
| Hgene | MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 163_170 | 439 | 1856 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 1338_1445 | 439 | 1829 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 914_1237 | 439 | 1829 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 1338_1445 | 439 | 1856 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 914_1237 | 439 | 1856 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 1534_1810 | 439 | 1829 | Domain | Dilute |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 69_763 | 439 | 1829 | Domain | Myosin motor |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 766_788 | 439 | 1829 | Domain | IQ 1 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 789_818 | 439 | 1829 | Domain | IQ 2 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 814_836 | 439 | 1829 | Domain | IQ 3 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 837_861 | 439 | 1829 | Domain | IQ 4 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 862_883 | 439 | 1829 | Domain | IQ 5 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 885_914 | 439 | 1829 | Domain | IQ 6 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 1534_1810 | 439 | 1856 | Domain | Dilute |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 69_763 | 439 | 1856 | Domain | Myosin motor |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 766_788 | 439 | 1856 | Domain | IQ 1 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 789_818 | 439 | 1856 | Domain | IQ 2 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 814_836 | 439 | 1856 | Domain | IQ 3 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 837_861 | 439 | 1856 | Domain | IQ 4 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 862_883 | 439 | 1856 | Domain | IQ 5 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 885_914 | 439 | 1856 | Domain | IQ 6 |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000356338 | - | 10 | 40 | 643_665 | 439 | 1829 | Region | Actin-binding |
| Hgene | >MYO5A | chr15:52689398 | chr15:41611978 | ENST00000399231 | - | 10 | 41 | 643_665 | 439 | 1856 | Region | Actin-binding |
| Tgene | OIP5 | chr15:52689398 | chr15:41611978 | ENST00000220514 | - | 1 | 5 | 75_174 | 129 | 230 | Domain | Mis18 |
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FusionGeneSequence for MYO5A_OIP5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MYO5A_ENST00000399231_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_540aa MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGTYNLLFCGSC GIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPENX >In-frame_MYO5A_ENST00000356338_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_540aa MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGTYNLLFCGSC GIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPENX >In-frame_MYO5A_ENST00000358212_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_540aa MKSSSLETMFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGTYNLLFCGSC GIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPENX >In-frame_MYO5A_ENST00000399233_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_540aa MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGTYNLLFCGSC GIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPENX >In-frame_MYO5A_ENST00000553916_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_540aa MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLR VRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAK LPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF CELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGTYNLLFCGSC GIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPENX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MYO5A_ENST00000399231_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_1620nt ATGGCTGCGTCGGAGCTCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA >In-frame_MYO5A_ENST00000356338_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_1620nt ATGGCTGCGTCGGAGCTCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA >In-frame_MYO5A_ENST00000358212_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_1620nt ATGAAATCTAGTAGTTTGGAAACTATGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA >In-frame_MYO5A_ENST00000399233_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_1620nt ATGGCTGCGTCGGAGCTCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA >In-frame_MYO5A_ENST00000553916_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_1620nt ATGGCTGCGTCGGAGCTCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MYO5A_ENST00000399231_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_2350nt ACCCCGGGCAGGTGGAGCGCTCGCGGCTGCTCGCGGCGAGCCCGGGAGTGATGGCGAGGCCCCTGCGGGCGGCCAGCGCCTGAGGCGCCC CGCCCCGCCCCGCCCCGCGCGGCCCTCCCCGCCCGGCCCTGCCCTGCCCTGCTCCCTGCCGGCGGCTGCGGGCGCTTCCTAGTCCGCTCG GGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGCTCTACACAAA GTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATAAAGTCCTCCT GCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTGACATACTTGT TGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATTCCAAACTTAT TTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATGCATACAGTGG TCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAAATCAGTCCAT CATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGA GGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATAATAGCAGCCG TTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGAAATCCAGAGT GGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAATGCTACGATT AGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGGCACATACTAG GCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAGGCAATGTTGG ATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTGTGGACTATGA GGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGGCCACAAATGC CCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTGCTGTCAAACA GCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGTGGGATTCCCGTTGGTTTCCATCTGTA TTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTGTGCTATCTCTTAAAAACAAAAGCCAT AGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAAGAGAAGATAGTGCTAACGCACAATCG CTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGATCCTGTACCAAAGCTTGAGTGTCAGG TTCAGGCTTTATTGCTGTCTTCAACAACAGGTGCTGCTTAGTCATTTCTTGAAAAAGATTGGCTTCAAGAATGGAGGGGAAATGCAGTTT CTATTTACCTTTAGGCTGATTTTCCAAATTATTTGTGAAGCTGTTTTTAGAAGATGAGAGACTAAGGATTCTTCTCTTTTATAGCTATTT GCCTTAAGAACTTACTTTAGATTCTTATTGAATTCATAATACTTATCTCTGAAAATGTCTTTGACTGTAAATTTAGGAATTAAGATGCAG AGTCCCATGTGTCCTCTGATCTAAAGTTGCATGGTTGGTCTGAAAATAGAGTTGGGCTTAATGTTGACTTCTATTACTCCTGCATGGAGC AGTTGTTATGAATACTAATACATCACTTTTTAACTTCTGTAAAATACAGATCATAATATTCTATAGGTAATGTTTAATAAATTGCCTGAA >In-frame_MYO5A_ENST00000356338_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_2180nt AGTCCGCTCGGGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGC TCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATA AAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTG ACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATT CCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATG CATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAA ATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTT CTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATA ATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGA AATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAA TGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGG CACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAG GCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTG TGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGG CCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTG CTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGTGGGATTCCCGTTGGTT TCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTGTGCTATCTCTTAAAAA CAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAAGAGAAGATAGTGCTAA CGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGATCCTGTACCAAAGCTT GAGTGTCAGGTTCAGGCTTTATTGCTGTCTTCAACAACAGGTGCTGCTTAGTCATTTCTTGAAAAAGATTGGCTTCAAGAATGGAGGGGA AATGCAGTTTCTATTTACCTTTAGGCTGATTTTCCAAATTATTTGTGAAGCTGTTTTTAGAAGATGAGAGACTAAGGATTCTTCTCTTTT ATAGCTATTTGCCTTAAGAACTTACTTTAGATTCTTATTGAATTCATAATACTTATCTCTGAAAATGTCTTTGACTGTAAATTTAGGAAT TAAGATGCAGAGTCCCATGTGTCCTCTGATCTAAAGTTGCATGGTTGGTCTGAAAATAGAGTTGGGCTTAATGTTGACTTCTATTACTCC TGCATGGAGCAGTTGTTATGAATACTAATACATCACTTTTTAACTTCTGTAAAATACAGATCATAATATTCTATAGGTAATGTTTAATAA >In-frame_MYO5A_ENST00000358212_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_2106nt ATGAAATCTAGTAGTTTGGAAACTATGTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGAT TATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCT CACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGA GTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGA GAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATG GCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTT GCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAA ACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGA ACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAG TTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGAT GATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCT GGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTC TGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCC ATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAAT CAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGT GGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTG TGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAA GAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGA TCCTGTACCAAAGCTTGAGTGTCAGGTTCAGGCTTTATTGCTGTCTTCAACAACAGGTGCTGCTTAGTCATTTCTTGAAAAAGATTGGCT TCAAGAATGGAGGGGAAATGCAGTTTCTATTTACCTTTAGGCTGATTTTCCAAATTATTTGTGAAGCTGTTTTTAGAAGATGAGAGACTA AGGATTCTTCTCTTTTATAGCTATTTGCCTTAAGAACTTACTTTAGATTCTTATTGAATTCATAATACTTATCTCTGAAAATGTCTTTGA CTGTAAATTTAGGAATTAAGATGCAGAGTCCCATGTGTCCTCTGATCTAAAGTTGCATGGTTGGTCTGAAAATAGAGTTGGGCTTAATGT TGACTTCTATTACTCCTGCATGGAGCAGTTGTTATGAATACTAATACATCACTTTTTAACTTCTGTAAAATACAGATCATAATATTCTAT >In-frame_MYO5A_ENST00000399233_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_2350nt ACCCCGGGCAGGTGGAGCGCTCGCGGCTGCTCGCGGCGAGCCCGGGAGTGATGGCGAGGCCCCTGCGGGCGGCCAGCGCCTGAGGCGCCC CGCCCCGCCCCGCCCCGCGCGGCCCTCCCCGCCCGGCCCTGCCCTGCCCTGCTCCCTGCCGGCGGCTGCGGGCGCTTCCTAGTCCGCTCG GGCGGCCGCCCAGGCGAGGTGCGGCCTCCGCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGCTCTACACAAA GTTTGCCAGGGTTTGGATACCTGATCCAGAGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATAAAGTCCTCCT GCTTCACCTCGAGGAAGGAAAGGATTTGGAATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTGACATACTTGT TGGTGAAAATGACCTCACAGCCCTCAGCTATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATTCCAAACTTAT TTATACGTATTGTGGTATAGTCCTAGTAGCTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATGCATACAGTGG TCAGAACATGGGTGATATGGATCCACATATCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAAATCAGTCCAT CATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGA GGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATAATAGCAGCCG TTTTGGGAAGTATATTGAGATTGGTTTTGATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGAAATCCAGAGT GGTATTCCAGGCAGAAGAGGAGAGAAACTATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAATGCTACGATT AGGAAATGCAGATAACTTTAATTACACAAAACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGGCACATACTAG GCAGGCCTGCACTTTGCTAGGAATTAGTGAATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAGGCAATGTTGG ATTTACATCCCGAGATGCAGACAGCTGCACAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTGTGGACTATGA GGAGATGTGTCACTGGCTCTGCCATCGGAAACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGGCCACAAATGC CCGCGATGCTTTGGCCAAGCACATCTATGCCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTGCTGTCAAACA GCACTCTTTTATTGGTGTGCTAGACATTTACGGTACTTACAACCTTTTATTCTGTGGTTCTTGTGGGATTCCCGTTGGTTTCCATCTGTA TTCTACCCATGCTGCCCTGGCTGCCTTGAGAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTGTGCTATCTCTTAAAAACAAAAGCCAT AGTAAATGCATCAGAGATGGATATTCAAAATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAAGAGAAGATAGTGCTAACGCACAATCG CTTAAAATCACTAATGAAGATTCTGAGTGAAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGATCCTGTACCAAAGCTTGAGTGTCAGG TTCAGGCTTTATTGCTGTCTTCAACAACAGGTGCTGCTTAGTCATTTCTTGAAAAAGATTGGCTTCAAGAATGGAGGGGAAATGCAGTTT CTATTTACCTTTAGGCTGATTTTCCAAATTATTTGTGAAGCTGTTTTTAGAAGATGAGAGACTAAGGATTCTTCTCTTTTATAGCTATTT GCCTTAAGAACTTACTTTAGATTCTTATTGAATTCATAATACTTATCTCTGAAAATGTCTTTGACTGTAAATTTAGGAATTAAGATGCAG AGTCCCATGTGTCCTCTGATCTAAAGTTGCATGGTTGGTCTGAAAATAGAGTTGGGCTTAATGTTGACTTCTATTACTCCTGCATGGAGC AGTTGTTATGAATACTAATACATCACTTTTTAACTTCTGTAAAATACAGATCATAATATTCTATAGGTAATGTTTAATAAATTGCCTGAA >In-frame_MYO5A_ENST00000553916_chr15_52689398_-_OIP5_ENST00000220514_chr15_41611978_-_2141nt GCACAGGCGGGGGGCGTAGGCGCGCGGGGCCCGCCATGGCTGCGTCGGAGCTCTACACAAAGTTTGCCAGGGTTTGGATACCTGATCCAG AGGAAGTCTGGAAGTCAGCAGAGCTGCTCAAAGATTATAAGCCAGGAGATAAAGTCCTCCTGCTTCACCTCGAGGAAGGAAAGGATTTGG AATACCATCTAGATCCAAAGACCAAGGAGCTGCCTCACTTACGAAATCCTGACATACTTGTTGGTGAAAATGACCTCACAGCCCTCAGCT ATCTTCATGAGCCTGCTGTGCTCCATAATCTCAGAGTCCGCTTTATTGATTCCAAACTTATTTATACGTATTGTGGTATAGTCCTAGTAG CTATAAATCCCTATGAACAGCTGCCTATTTATGGAGAAGATATTATTAATGCATACAGTGGTCAGAACATGGGTGATATGGATCCACATA TCTTTGCAGTAGCTGAAGAAGCTTACAAGCAAATGGCCAGAGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAA AAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCT CCAACCCCATCATGGAGTCCATTGGAAATGCTAAAACAACCAGGAATGATAATAGCAGCCGTTTTGGGAAGTATATTGAGATTGGTTTTG ATAAGAGATATCGAATCATTGGTGCCAATATGAGAACTTATCTTTTAGAGAAATCCAGAGTGGTATTCCAGGCAGAAGAGGAGAGAAACT ATCATATCTTCTATCAGCTTTGTGCCTCAGCAAAGTTACCTGAATTTAAAATGCTACGATTAGGAAATGCAGATAACTTTAATTACACAA AACAAGGAGGCAGTCCTGTGATTGAAGGAGTGGATGATGCAAAGGAGATGGCACATACTAGGCAGGCCTGCACTTTGCTAGGAATTAGTG AATCTCATCAAATGGGAATTTTCCGAATACTTGCTGGCATCCTTCACTTAGGCAATGTTGGATTTACATCCCGAGATGCAGACAGCTGCA CAATACCTCCCAAGCATGAACCTCTCTGCATCTTCTGTGAACTCATGGGTGTGGACTATGAGGAGATGTGTCACTGGCTCTGCCATCGGA AACTGGCTACTGCCACAGAGACATACATCAAGCCCATCTCCAAGCTGCAGGCCACAAATGCCCGCGATGCTTTGGCCAAGCACATCTATG CCAAGCTCTTTAACTGGATTGTAGATAATGTCAATCAGGCTCTCCATTCTGCTGTCAAACAGCACTCTTTTATTGGTGTGCTAGACATTT ACGGTACTTACAACCTTTTATTCTGTGGTTCTTGTGGGATTCCCGTTGGTTTCCATCTGTATTCTACCCATGCTGCCCTGGCTGCCTTGA GAGGTCACTTCTGCCTTTCCAGTGACAAAATGGTGTGCTATCTCTTAAAAACAAAAGCCATAGTAAATGCATCAGAGATGGATATTCAAA ATGTTCCTCTATCAGAAAAGATTGCAGAGCTGAAAGAGAAGATAGTGCTAACGCACAATCGCTTAAAATCACTAATGAAGATTCTGAGTG AAGTGACTCCTGACCAGTCCAAGCCAGAAAACTGATCCTGTACCAAAGCTTGAGTGTCAGGTTCAGGCTTTATTGCTGTCTTCAACAACA GGTGCTGCTTAGTCATTTCTTGAAAAAGATTGGCTTCAAGAATGGAGGGGAAATGCAGTTTCTATTTACCTTTAGGCTGATTTTCCAAAT TATTTGTGAAGCTGTTTTTAGAAGATGAGAGACTAAGGATTCTTCTCTTTTATAGCTATTTGCCTTAAGAACTTACTTTAGATTCTTATT GAATTCATAATACTTATCTCTGAAAATGTCTTTGACTGTAAATTTAGGAATTAAGATGCAGAGTCCCATGTGTCCTCTGATCTAAAGTTG CATGGTTGGTCTGAAAATAGAGTTGGGCTTAATGTTGACTTCTATTACTCCTGCATGGAGCAGTTGTTATGAATACTAATACATCACTTT |
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FusionGenePPI for MYO5A_OIP5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MYO5A | MLPH, DYNLL2, DLGAP1, DYNLL1, SHANK2, RAB27A, BMF, EXOC3, EXOC4, EXOC6, SIRT7, FBXO25, HGS, TRIM3, GRIA2, GRIA1, PAN2, CCDC8, PEX19, CREB3, SCP2, DTNBP1, MYH11, CAPZA2, MYO1E, PLS3, NTRK1, CDK2, DBN1, FLNA, MYH9, MYO1C, PPP1CB, IQGAP1, PDLIM7, SYNPO, LIMA1, ANLN, MYO5C, MYO19, MYO18A, FBXW7, SSH1, DKK3, CDH5, TMOD4, UBE2O, TMOD3, EID1, FEZ1, OS9, PPP6R2, MYL2, LRRIQ1, AVIL, FAM160B2, IL20RA, TRIM25 | OIP5 | RAF1, TMPO, ABL2, PEX19, CASP10, FOXJ1, RARG, TSSK3, KDM1A, CUL1, CUL3, CUL4B, BTRC, KRT15, SKIL, TPM3, TRIP6, NUP62, TFIP11, MIS18A, EIF4ENIF1, GCC1, C1orf94, CEP170P1, CEP170, UBE2T, RNF40, QKI, TRAF7, SNAP47, PDZRN3, CYTH3, MED29, STX1A, MIS18BP1, CUEDC1, C9orf16, KRAS, EZH2, GTF2E2, TACC3, CENPA, NCAPH2, CAV3, NOS1AP, PKN3, NCKAP5L, TFPT, CCHCR1, YEATS4, TUFT1, RABGAP1L, GOLGA5, CLOCK, PSMD9, VPS53, DZIP3, GRIPAP1, RCOR1, HMG20A, CCDC132, CCDC93, PHF21A, PTRF, PHLDB3, HAUS6, RPRD1A, ARNTL, MAX, GIT2, RABGEF1, NUF2, THAP11, VPS51, TSSC1, JUN, OIP5, HJURP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MYO5A_OIP5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MYO5A_OIP5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MYO5A | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Hgene | MYO5A | C0031117 | Peripheral Neuropathy | 1 | CTD_human |
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