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Fusion gene ID: 22929 |
FusionGeneSummary for MXRA8_CDK11A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MXRA8_CDK11A | Fusion gene ID: 22929 | Hgene | Tgene | Gene symbol | MXRA8 | CDK11A | Gene ID | 54587 | 728642 |
| Gene name | matrix remodeling associated 8 | cyclin dependent kinase 11A | |
| Synonyms | ASP3 | CDC2L2|CDC2L3|CDK11-p110|CDK11-p46|CDK11-p58|PITSLRE|p58GTA | |
| Cytomap | 1p36.33 | 1p36.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | matrix remodeling-associated protein 8limitrinmatrix-remodeling-associated protein 8matrix-remodelling associated 8 | cyclin-dependent kinase 11APITSLRE BPITSLRE protein kinase beta SV1 isoformPITSLRE protein kinase beta SV16 isoformPITSLRE protein kinase beta SV17 isoformPITSLRE protein kinase beta SV18 isoformPITSLRE protein kinase beta SV2 isoformPITSLRE protei | |
| Modification date | 20180403 | 20180523 | |
| UniProtAcc | Q9BRK3 | Q9UQ88 | |
| Ensembl transtripts involved in fusion gene | ENST00000309212, ENST00000342753, ENST00000445648, ENST00000477278, | ENST00000356200, ENST00000378638, ENST00000378633, ENST00000357760, ENST00000404249, ENST00000358779, ENST00000495016, ENST00000378635, | |
| Fusion gene scores | * DoF score | 4 X 2 X 3=24 | 2 X 2 X 2=8 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/24*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: MXRA8 [Title/Abstract] AND CDK11A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CDK11A | GO:0006468 | protein phosphorylation | 12501247 |
| Tgene | CDK11A | GO:0050684 | regulation of mRNA processing | 12501247 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-43-5670-01A | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000309212 | ENST00000356200 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| In-frame | ENST00000309212 | ENST00000378638 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000309212 | ENST00000378633 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000309212 | ENST00000357760 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000309212 | ENST00000404249 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000309212 | ENST00000358779 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-intron | ENST00000309212 | ENST00000495016 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000309212 | ENST00000378635 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| In-frame | ENST00000342753 | ENST00000356200 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| In-frame | ENST00000342753 | ENST00000378638 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000342753 | ENST00000378633 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000342753 | ENST00000357760 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000342753 | ENST00000404249 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000342753 | ENST00000358779 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-intron | ENST00000342753 | ENST00000495016 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000342753 | ENST00000378635 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| In-frame | ENST00000445648 | ENST00000356200 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| In-frame | ENST00000445648 | ENST00000378638 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000445648 | ENST00000378633 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000445648 | ENST00000357760 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000445648 | ENST00000404249 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000445648 | ENST00000358779 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-intron | ENST00000445648 | ENST00000495016 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| 5CDS-5UTR | ENST00000445648 | ENST00000378635 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-3CDS | ENST00000477278 | ENST00000356200 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-3CDS | ENST00000477278 | ENST00000378638 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-5UTR | ENST00000477278 | ENST00000378633 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-5UTR | ENST00000477278 | ENST00000357760 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-5UTR | ENST00000477278 | ENST00000404249 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-5UTR | ENST00000477278 | ENST00000358779 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-intron | ENST00000477278 | ENST00000495016 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
| intron-5UTR | ENST00000477278 | ENST00000378635 | MXRA8 | chr1 | 1293836 | - | CDK11A | chr1 | 1654270 | - |
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FusionProtFeatures for MXRA8_CDK11A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MXRA8 | CDK11A |
| May play a role in the maturation and maintenance ofblood-brain barrier. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000358779 | - | 0 | 20 | 15_381 | -5 | 771 | Compositional bias | Note=Glu-rich |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000378633 | - | 0 | 20 | 15_381 | -5 | 784 | Compositional bias | Note=Glu-rich |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000404249 | - | 0 | 20 | 15_381 | -5 | 781 | Compositional bias | Note=Glu-rich |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000358779 | - | 0 | 20 | 427_647 | -5 | 771 | Domain | Protein kinase |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000378633 | - | 0 | 20 | 427_647 | -5 | 784 | Domain | Protein kinase |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000404249 | - | 0 | 20 | 427_647 | -5 | 781 | Domain | Protein kinase |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000358779 | - | 0 | 20 | 432_440 | -5 | 771 | Nucleotide binding | ATP |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000378633 | - | 0 | 20 | 432_440 | -5 | 784 | Nucleotide binding | ATP |
| Tgene | >CDK11A | chr1:1293836 | chr1:1654270 | ENST00000404249 | - | 0 | 20 | 432_440 | -5 | 781 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 364_367 | 16 | 443 | Compositional bias | Note=Poly-Arg |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 364_367 | 16 | 451 | Compositional bias | Note=Poly-Arg |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 160_288 | 16 | 443 | Domain | Note=Ig-like V-type 2 |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 29_157 | 16 | 443 | Domain | Note=Ig-like V-type 1 |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 160_288 | 16 | 451 | Domain | Note=Ig-like V-type 2 |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 29_157 | 16 | 451 | Domain | Note=Ig-like V-type 1 |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 20_341 | 16 | 443 | Topological domain | Extracellular |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 363_442 | 16 | 443 | Topological domain | Cytoplasmic |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 20_341 | 16 | 451 | Topological domain | Extracellular |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 363_442 | 16 | 451 | Topological domain | Cytoplasmic |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000309212 | - | 1 | 10 | 342_362 | 16 | 443 | Transmembrane | Helical |
| Hgene | >MXRA8 | chr1:1293836 | chr1:1654270 | ENST00000445648 | - | 1 | 10 | 342_362 | 16 | 451 | Transmembrane | Helical |
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FusionGeneSequence for MXRA8_CDK11A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_16aa >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_16aa >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_16aa >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_16aa >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_16aa >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_16aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_49nt >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_49nt >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_49nt >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_49nt >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_49nt >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_49nt |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_2733nt GTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATGTTTTAACT CAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAA GCAGAGATAAAACGCTTAAAAAATGTAAGCCATATTTTTTTAAGTAAGTGGTTTTCTTAAAGGAGATTTAATTTCTTTGCCCTCATTTTT CCATTAGAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAG GAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAA GATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAAAGAGAAAAGAAAAATGT AGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAGAAGAACAG GATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGCAGTTA GAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGG CGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGG AGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGAC CTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAG GAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAG GAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAA AATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGA ACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGCTGCCCAAG TACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGA GCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAGG GAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATC GTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATC CAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGC ATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGTACCGC GCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAG AAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGC TACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGAC CAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGC GAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGG CCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCC TCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGGAGAACTCAGCCGGGACCACAGGCGTGGC TACTGCGGCTGGAGCTGCGATGAGACTCGGAACTCCTCGTCTTACTTTGTGCTCCATGTTTTGTTTTTGTATTTTGGTTTGTAAATTTGT >In-frame_MXRA8_ENST00000309212_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_2509nt GTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATGTTTTAACT CAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAA GCAGAGATAAAACGCTTAAAAAATAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCA AGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCAATGG AAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAA AGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAAC GACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGG ACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGC GGCGGGCGGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAG TGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGA AAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAAT CAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGG AAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTG AAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGG AAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCA AGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCT ATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCC CGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACA TGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGG TGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGC TGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGG TGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCG GGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTG AGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCG GGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCA AGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGC GGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCA >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_2738nt GCCGAGTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATGTTT TAACTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGG AGAAAGCAGAGATAAAACGCTTAAAAAATGTAAGCCATATTTTTTTAAGTAAGTGGTTTTCTTAAAGGAGATTTAATTTCTTTGCCCTCA TTTTTCCATTAGAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCAAGCGGGATTCCC TTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAG AAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAAAGAGAAAAGAAA AATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAGAAG AACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGC AGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGG AGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCC ACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAA GGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTT CTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGG AGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAAC GAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTG AGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGCTGC CCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCT ACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCC TGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCT ACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGA TGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACG CCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGT ACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGA CTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGC CCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCT CAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATT TCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCC CGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGG GGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGGAGAACTCAGCCGGGACCACAGGC GTGGCTACTGCGGCTGGAGCTGCGATGAGACTCGGAACTCCTCGTCTTACTTTGTGCTCCATGTTTTGTTTTTGTATTTTGGTTTGTAAA >In-frame_MXRA8_ENST00000342753_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_2514nt GCCGAGTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATGTTT TAACTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGG AGAAAGCAGAGATAAAACGCTTAAAAAATAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGA TTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTC AATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGA TGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCG GAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGA AAGGGACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCG CGAGCGGCGGGCGGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGA CAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGA AGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGC GGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGA GGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAAT GAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGC AGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGA GCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGG CACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGG CTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAG CAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGG GGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAA CCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGT CGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCAT CTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCC CAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCG CTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGG CCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGT GAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCT >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000356200_chr1_1654270_-_2741nt AGAGCCGAGTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATG TTTTAACTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAG AGGAGAAAGCAGAGATAAAACGCTTAAAAAATGTAAGCCATATTTTTTTAAGTAAGTGGTTTTCTTAAAGGAGATTTAATTTCTTTGCCC TCATTTTTCCATTAGAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCAAGCGGGATT CCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCAATGGAAGACAGAG GAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAAAGAGAAAAG AAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAG AAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGG AGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGG AGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCA GCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAG AAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAG GTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAG AGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAG AACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGG GTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGC TGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGG TCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGT CCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGA TCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCC TGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCC ACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGT GGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGC TGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCT GGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGC TCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGT ATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCA GCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACC AGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGGAGAACTCAGCCGGGACCACA GGCGTGGCTACTGCGGCTGGAGCTGCGATGAGACTCGGAACTCCTCGTCTTACTTTGTGCTCCATGTTTTGTTTTTGTATTTTGGTTTGT >In-frame_MXRA8_ENST00000445648_chr1_1293836_-_CDK11A_ENST00000378638_chr1_1654270_-_2517nt AGAGCCGAGTGGGACAAAGCCTGGGGCTGGGCGGGGGCCATGGCGCTGCCATCCCGAATCCTGCTTTGGAAACTTGTGCTTCTGCAGATG TTTTAACTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAG AGGAGAAAGCAGAGATAAAACGCTTAAAAAATAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCG GGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGA CTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAA AGATGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACG TCGGAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAG AGAAAGGGACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGA GCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAG CGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAA AGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTC AGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGA GGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGA AATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGA AGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCAT CGAGCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGA GGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGA GGGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGG CAGCAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCC AGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTC CAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCC GGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTG CATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGAC CCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAA GCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGA CGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCG TGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCA |
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FusionGenePPI for MXRA8_CDK11A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MXRA8 | CDK11A | SKIV2L, PAK1, EIF3F, CCNL2, CCNL1, B4GALT1, RNPS1, SMAD3, HSP90AA1, CSNK2A1, SOX2, GADD45A, CSNK2A2, CSNK2B, PRPF40A, RBM25, PSMD1, KPNA2, C18orf25, A2M, KPNB1, HKR1, ZNF267, ZNF460, ZNF510, ZFP14, ZNF33A, CDKN2A, NOP58, PIN1, CDC37, FKBP5, WDR47, DDB2, CDK11B, ZG16B, C12orf43, SPRR3, CRNN, AP3B1, CTR9, DPF2, LEO1, NOLC1, PELP1, SAP30BP, SUPT16H, MED4, AP4M1, FOXK2, HSP90AB3P, HSP90AA5P, HSP90AB1, CCT6B, CCT6A, CCT2, CCT3, CCT4, USP15, SPAG9, MCM2, MCM4, MCM6, EPS15L1, IVNS1ABP, NCL, PDHA1, UHRF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MXRA8_CDK11A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MXRA8_CDK11A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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