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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 22553

FusionGeneSummary for MRPS22_SLC9A9

check button Fusion gene summary
Fusion gene informationFusion gene name: MRPS22_SLC9A9
Fusion gene ID: 22553
HgeneTgene
Gene symbol

MRPS22

SLC9A9

Gene ID

56945

285195

Gene namemitochondrial ribosomal protein S22solute carrier family 9 member A9
SynonymsC3orf5|COXPD5|GIBT|GK002|MRP-S22|RPMS22AUTS16|NHE9
Cytomap

3q23

3q24

Type of geneprotein-codingprotein-coding
Description28S ribosomal protein S22, mitochondrialS22mtmitochondrial small ribosomal subunit protein mS22sodium/hydrogen exchanger 9Na(+)/H(+) exchanger 9putative protein product of Nbla00118sodium/proton exchanger NHE9solute carrier family 9 (sodium/hydrogen exchanger)solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
Modification date2018052320180523
UniProtAcc

P82650

Q8IVB4

Ensembl transtripts involved in fusion geneENST00000495075, ENST00000310776, 
ENST00000465056, ENST00000478464, 
ENST00000489521, 
ENST00000316549, 
ENST00000498717, 
Fusion gene scores* DoF score4 X 4 X 2=327 X 7 X 5=245
# samples 47
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MRPS22 [Title/Abstract] AND SLC9A9 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUADTCGA-67-3774-01AMRPS22chr3

139071634

+SLC9A9chr3

143412149

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000495075ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000495075ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000310776ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000310776ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000465056ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000465056ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000478464ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000478464ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
intron-3CDSENST00000489521ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
intron-intronENST00000489521ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-

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FusionProtFeatures for MRPS22_SLC9A9


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MRPS22

P82650

SLC9A9

Q8IVB4

May act in electroneutral exchange of protons for Na(+)across membranes. Involved in the effusion of Golgi luminal H(+)in exchange for cytosolic cations. Involved in organelle ionhomeostasis by contributing to the maintenance of the uniqueacidic pH values of the Golgi and post-Golgi compartments in thecell. {ECO:0000269|PubMed:15522866}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316204_224177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316236_256177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316278_298177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316302_322177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316323_343177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316365_385177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316387_407177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316430_450177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316466_486177646TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316127_147177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-316165_185177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-31621_41177646TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549-31646_66177646TransmembraneHelical


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FusionGeneSequence for MRPS22_SLC9A9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MRPS22_ENST00000495075_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_761aa
MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAAESGSPETKKPTFMDEEVQSILTKMTGLNLQKT
FKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGT
LRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGG
MVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA
VAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGI
VAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQ
KIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDK
NMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARL

>In-frame_MRPS22_ENST00000310776_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_761aa
MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAAESGSPETKKPTFMDEEVQSILTKMTGLNLQKT
FKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGT
LRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGG
MVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA
VAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGI
VAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQ
KIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDK
NMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARL

>In-frame_MRPS22_ENST00000465056_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_760aa
MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAESGSPETKKPTFMDEEVQSILTKMTGLNLQKTF
KPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGTL
RKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGGM
VWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAV
AIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIV
AVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQK
IPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKN
MTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLG

>In-frame_MRPS22_ENST00000478464_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_720aa
MSRNETEHRYLGTHFGAESGSPETKKPTFMDEEVQSILTKMTGLNLQKTFKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPV
LEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQ
DRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGGMVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKN
GDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSF
AMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVI
FCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTL
LLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWC
GPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLNX


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MRPS22_ENST00000495075_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_2283nt
ATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAG
CCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGCAGAATCT
GGTAGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACT
TTTAAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAG
GCAGCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGA
ACAGAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACA
CTACGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTC
AAGGAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACA
GAGTATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGA
ATGGTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTG
AAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGAT
CCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCA
GTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTG
GGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTG
TGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATA
GTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTT
GAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTT
TTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAG
AAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCT
CAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACT
TGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAA
AACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGT
CCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAG
GATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTA
GGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTT

>In-frame_MRPS22_ENST00000310776_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_2283nt
ATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAG
CCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGCAGAATCT
GGTAGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACT
TTTAAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAG
GCAGCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGA
ACAGAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACA
CTACGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTC
AAGGAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACA
GAGTATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGA
ATGGTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTG
AAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGAT
CCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCA
GTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTG
GGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTG
TGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATA
GTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTT
GAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTT
TTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAG
AAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCT
CAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACT
TGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAA
AACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGT
CCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAG
GATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTA
GGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTT

>In-frame_MRPS22_ENST00000465056_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_2280nt
ATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAG
CCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGAATCTGGT
AGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTT
AAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCA
GCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACA
GAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTA
CGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAG
GAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAG
TATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATG
GTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAG
GCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCA
GTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTG
GCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGG
AATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGT
GAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTT
GCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAA
TTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTT
ATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAG
ATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAG
CCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGG
CTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAAC
ATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCT
CCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGAT
GATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGT
CTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAG

>In-frame_MRPS22_ENST00000478464_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_2160nt
ATGTCCAGAAATGAGACTGAGCACAGATATTTGGGAACCCATTTTGGAGCAGAATCTGGTAGCCCAGAGACCAAGAAACCTACATTTATG
GATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTTAAGCCAGCTATACAAGAACTGAAGCCACCA
ACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCAGCTAAAGTACGATTAAAAATGCCACCAGTT
CTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACAGAAACAACCAAATATGTGTTTACTGATATA
TCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTACGCAAAGCCTCTTGGGAAGAACGGGACCGA
ATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAGGAAGAAAATCTTAGGACTATGTATAGCCAG
GACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAGTATATCAAGGTTCATCACAAGACCTATGAA
GATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATGGTGTGGTATTTTGTAAATAATAAAAAGATT
GATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCTGGCCAGCTGAAAAAT
GGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCCATTTTCCATGAACTG
CACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACATATTCTATATCCATT
TACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATCTTCGCTGGCTCATTT
GCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTGGAAACCGGCCTGTTT
TTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGTGGAGTCACACAAGCA
CATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTGGCGGAGAACGTCATC
TTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTTCTAGCAATTTTTGTT
GCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTTCAGCACATGATGATG
TTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATGTTTACCACTACGCTG
CTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTTGGCGTGGACCTGGAT
GAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAGAGTGCTCGGCTCTTC
AGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACATTACCTGAATGGTGT
GGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATTGTAAACCAGGATGAA
CTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCTTCACCCCAGACGCCA
GGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAATCCCAGTTGAATTAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_MRPS22_ENST00000495075_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_4195nt
CCTCTTCCTGGGCGGCGATCTCTGGGACAGATGCGCAGAAGACTTCCTGCTCAACGACGACGTCCTCCCTGAGAGCGCCCAGGAAAACGT
CCACTTCCAGCCCAGCAGACGAGTCGTCCTGCGCTCCTGAGCGTTCGTCGACAGAGCTCAGGAGGACCTCTGGGATCAGGATGAGGGTGT
GTCCATCGAGAGACACTCGCAGGATCGACGTTGGCGGGAGCTCCAGCACCAGGTCGACGTCGTCCAGGGGCACACGCAGGGCACAGCCCG
CGGCCAGGACCACTATGGAGCACTTTGAGTATATCATCCCACTGTCTCCTGGAGGGCAAGATTCAGCCTTAAGGGGGTTCCCTTGTATGT
GAGTGCTGCAAGAACTGGGTGTGACTCGGAATCCCTCCCAACCACTTCCGGCGCAAGTGGCTTCTGATAATCATGGCGCCCCTCGGAACA
ACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAGCCCTGGCACGGTGGCCTG
CTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGCAGAATCTGGTAGCCCAGAGACCAAG
AAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTTAAGCCAGCTATACAA
GAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCAGCTAAAGTACGATTA
AAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACAGAAACAACCAAATAT
GTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTACGCAAAGCCTCTTGG
GAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAGGAAGAAAATCTTAGG
ACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAGTATATCAAGGTTCAT
CACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATGGTGTGGTATTTTGTA
AATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCT
GGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCC
ATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACA
TATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATC
TTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTG
GAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGT
GGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTG
GCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTT
CTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTT
CAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATG
TTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTT
GGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAG
AGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACA
TTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATT
GTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCT
TCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAA
TCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGCCAAGCTGATGAGGCA
GTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCTGGTGCCTGAAGAAAT
GAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGGCTGGGGTGGGGATGG
AGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGGCTCTCCAGGCCCTTC
ACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTTTGCTCCTAAGCTGAA
GGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCCCAGGGCAGAGCCCAG
AGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGCATCCTTCTTATGCTA
CTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTAGTAGGACCATTCCAA
GAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGTCACTTCTTGGCTGTG
CAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCAGACTGTGCAGGAGCC
CCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATGATGTGTGGGTTACAC
TGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACATGATAGCTTTTAATT
CAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATATTAGACTCGAAAAAA
TAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGACCCAAAGCTTAAAAG
TAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTATGTGCATCAATTATT
TTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTAAATATGACAAGTGGT

>In-frame_MRPS22_ENST00000310776_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_3771nt
TGATAATCATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTC
GAATCCAGCCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCG
CAGAATCTGGTAGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGC
AGAAGACTTTTAAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGG
CAGTTGAGGCAGCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTT
TGGAAGGAACAGAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAA
GTGGCACACTACGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAA
TAATTTTCAAGGAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAG
ATTCCACAGAGTATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACT
TTGGTGGAATGGTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATG
GTTTTGTGAAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTG
CTACAGATCCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGA
ATGATGCAGTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCC
AGTCTGTGGGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTA
CCAAGCTGTGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAA
CAGGGATAGTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAAC
AGTTGTTTGAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTA
ATGCTCTTTTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCC
GAAAACAGAAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACA
CAGAATCTCAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCA
TGTTGACTTGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACT
TGGATAAAAACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCC
ACTCTGGTCCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGC
TAAAAGAGGATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTG
CAAGGCTAGGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAAC
TCAAGCTTGAGCAAACTTTGGGTCAATCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGA
GGAATACAAGCCAAGCTGATGAGGCAGTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCAC
ATGGATCCTCTGGTGCCTGAAGAAATGAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGAT
TACTGGATTGGCTGGGGTGGGGATGGAGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGC
TGCGAATGCGGCTCTCCAGGCCCTTCACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAG
AGTAAACATTTTGCTCCTAAGCTGAAGGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCT
CTCAGTGACCCCAGGGCAGAGCCCAGAGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTG
TTCTTCTTGGCATCCTTCTTATGCTACTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCAC
TTTCAAGCTTAGTAGGACCATTCCAAGAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCC
TGCATGTGAGTCACTTCTTGGCTGTGCAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCT
ACCTGGCAGCAGACTGTGCAGGAGCCCCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAA
CAGAGCCAATGATGTGTGGGTTACACTGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCC
AGAGACCAACATGATAGCTTTTAATTCAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCC
AGATGTTCATATTAGACTCGAAAAAATAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACA
TCTTCCTTGGACCCAAAGCTTAAAAGTAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAG
GCACACTGCTATGTGCATCAATTATTTTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGT

>In-frame_MRPS22_ENST00000465056_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_3760nt
ATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAG
CCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGAATCTGGT
AGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTT
AAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCA
GCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACA
GAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTA
CGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAG
GAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAG
TATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATG
GTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAG
GCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCA
GTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTG
GCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGG
AATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGT
GAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTT
GCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAA
TTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTT
ATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAG
ATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAG
CCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGG
CTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAAC
ATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCT
CCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGAT
GATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGT
CTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAG
CAAACTTTGGGTCAATCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGC
CAAGCTGATGAGGCAGTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCT
GGTGCCTGAAGAAATGAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGG
CTGGGGTGGGGATGGAGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGG
CTCTCCAGGCCCTTCACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTT
TGCTCCTAAGCTGAAGGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCC
CAGGGCAGAGCCCAGAGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGC
ATCCTTCTTATGCTACTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTA
GTAGGACCATTCCAAGAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGT
CACTTCTTGGCTGTGCAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCA
GACTGTGCAGGAGCCCCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATG
ATGTGTGGGTTACACTGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACA
TGATAGCTTTTAATTCAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATA
TTAGACTCGAAAAAATAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGA
CCCAAAGCTTAAAAGTAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTA
TGTGCATCAATTATTTTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTA

>In-frame_MRPS22_ENST00000478464_chr3_139071634_+_SLC9A9_ENST00000316549_chr3_143412149_-_3745nt
GGAAGGTCAGGGAAGGGTTCCTGGCAAATATGACCAAAGCTGAGATCTGGTTAGCCATGCTAAGGAGAAAGCAAGAAGCTTCTCAAGCAT
AGGGGACAGTAGCAGATGTCCAGAAATGAGACTGAGCACAGATATTTGGGAACCCATTTTGGAGCAGAATCTGGTAGCCCAGAGACCAAG
AAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTTAAGCCAGCTATACAA
GAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCAGCTAAAGTACGATTA
AAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACAGAAACAACCAAATAT
GTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTACGCAAAGCCTCTTGG
GAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAGGAAGAAAATCTTAGG
ACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAGTATATCAAGGTTCAT
CACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATGGTGTGGTATTTTGTA
AATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCT
GGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCC
ATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACA
TATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATC
TTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTG
GAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGT
GGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTG
GCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTT
CTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTT
CAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATG
TTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTT
GGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAG
AGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACA
TTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATT
GTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCT
TCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAA
TCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGCCAAGCTGATGAGGCA
GTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCTGGTGCCTGAAGAAAT
GAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGGCTGGGGTGGGGATGG
AGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGGCTCTCCAGGCCCTTC
ACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTTTGCTCCTAAGCTGAA
GGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCCCAGGGCAGAGCCCAG
AGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGCATCCTTCTTATGCTA
CTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTAGTAGGACCATTCCAA
GAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGTCACTTCTTGGCTGTG
CAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCAGACTGTGCAGGAGCC
CCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATGATGTGTGGGTTACAC
TGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACATGATAGCTTTTAATT
CAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATATTAGACTCGAAAAAA
TAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGACCCAAAGCTTAAAAG
TAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTATGTGCATCAATTATT
TTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTAAATATGACAAGTGGT


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FusionGenePPI for MRPS22_SLC9A9


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.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MRPS22NFKBIL1, UBC, MYC, ICT1, HDGF, CUL3, CUL1, COPS5, CAND1, MRPS18B, MRPS25, MRPS35, MRPS26, QARS, TMEM126A, BARD1, SMURF1, ESR2, C1QBP, UBL4A, SOX2, TARDBP, PARK2, SMURF2, GRSF1, AURKA, CEP250, HAUS2, TP53, SHMT2, RNF2, BTRC, FBXW11, TRA2A, RPL6, ZC3H3, RPS8, TRMT10B, HNRNPA1, ZNF707, LUC7L, MRPS31, MRPS5, MRPS11, RPS6KB2, NTRK1, FAM192A, DAP3, MRPS2, MRPS27, MRPS28, MRPS9, MRPS23, PTCD3, BTK, SHD, NPM1, GBA2, ERBB3, POU5F1, MRPS34, GLTSCR2, MRPS15, SNRNP70, E4F1, DLDSLC9A9ZDHHC17, TP53


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MRPS22_SLC9A9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MRPS22_SLC9A9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMRPS22C1458155Mammary Neoplasms1CTD_human
HgeneMRPS22C2673642Combined Oxidative Phosphorylation Deficiency 51CTD_human;ORPHANET;UNIPROT
TgeneSLC9A9C0004352Autistic Disorder1CTD_human