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Fusion gene ID: 22343 |
FusionGeneSummary for MPHOSPH10_ATP6V1B1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MPHOSPH10_ATP6V1B1 | Fusion gene ID: 22343 | Hgene | Tgene | Gene symbol | MPHOSPH10 | ATP6V1B1 | Gene ID | 10199 | 525 |
| Gene name | M-phase phosphoprotein 10 | ATPase H+ transporting V1 subunit B1 | |
| Synonyms | CT90|MPP10|MPP10P|PPP1R106 | ATP6B1|RTA1B|VATB|VMA2|VPP3 | |
| Cytomap | 2p13.3 | 2p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | U3 small nucleolar ribonucleoprotein protein MPP10U3 small nucleolar ribonucleoproteinm phase phosphoprotein 10protein phosphatase 1, regulatory subunit 106 | V-type proton ATPase subunit B, kidney isoformATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1H(+)-transporting two-sector ATPase, 58kD subunitH+-ATPase beta 1 subunitV-ATPase B1 subunitV-ATPase subunit B 1endomembrane proton pump 58 kDa s | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | O00566 | P15313 | |
| Ensembl transtripts involved in fusion gene | ENST00000244230, ENST00000498451, ENST00000468427, | ENST00000234396, ENST00000412314, | |
| Fusion gene scores | * DoF score | 5 X 6 X 2=60 | 1 X 1 X 1=1 |
| # samples | 38 | 1 | |
| ** MAII score | log2(38/60*10)=2.66296501272243 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: MPHOSPH10 [Title/Abstract] AND ATP6V1B1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MPHOSPH10 | GO:0010923 | negative regulation of phosphatase activity | 19389623 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1846-01A | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000244230 | ENST00000234396 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| In-frame | ENST00000244230 | ENST00000412314 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| In-frame | ENST00000498451 | ENST00000234396 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| In-frame | ENST00000498451 | ENST00000412314 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| intron-3CDS | ENST00000468427 | ENST00000234396 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
| intron-3CDS | ENST00000468427 | ENST00000412314 | MPHOSPH10 | chr2 | 71361927 | + | ATP6V1B1 | chr2 | 71185176 | + |
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FusionProtFeatures for MPHOSPH10_ATP6V1B1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MPHOSPH10 | ATP6V1B1 |
| Component of the 60-80S U3 small nucleolarribonucleoprotein (U3 snoRNP). Required for the early cleavagesduring pre-18S ribosomal RNA processing. | Non-catalytic subunit of the peripheral V1 complex ofvacuolar ATPase. V-ATPase is responsible for acidifying a varietyof intracellular compartments in eukaryotic cells. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 109_138 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 205_239 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 284_324 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 134_137 | 366 | 682 | Compositional bias | Note=Poly-Glu |
| Hgene | MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 229_232 | 366 | 682 | Compositional bias | Note=Poly-Glu |
| Tgene | >ATP6V1B1 | chr2:71361927 | chr2:71185176 | ENST00000234396 | + | 1 | 14 | 510_513 | 58 | 514 | Motif | Note=PDZ-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 348_382 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 469_490 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 574_604 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 648_670 | 366 | 682 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MPHOSPH10 | chr2:71361927 | chr2:71185176 | ENST00000244230 | + | 4 | 11 | 666_670 | 366 | 682 | Compositional bias | Note=Poly-Lys |
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FusionGeneSequence for MPHOSPH10_ATP6V1B1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_822aa MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQY FQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKL EQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFF DPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSF EKRQEKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAE DFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNM ETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMY TDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDV SNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREG >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_805aa MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQY FQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKL EQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFF DPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSF EKRQEKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAE DFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNM ETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMY TDLATIYERAGRVEDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAM >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_822aa MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQY FQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKL EQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFF DPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSF EKRQEKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAE DFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNM ETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMY TDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDV SNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREG >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_805aa MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQY FQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKL EQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFF DPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSF EKRQEKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAE DFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNM ETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMY TDLATIYERAGRVEDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAM |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_2466nt ATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACG ATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGA AGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATAC TTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCA GAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAG AGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTG GAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATG GAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATT GATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTT GATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAA GCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGA GTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTT GAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAG GTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATC CTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAG GACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGAC GTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGC CAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATG GAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACG ATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACG GACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTAC ACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGGTCGGGGAGGATCCATCACACAGATCCCCATCCTCACCATGCCCAAC GACGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTACGTGGACAGACAGCTTCACAACAGACAGATC TACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTC TCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGAC CTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGAC CTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGCCGTGATCGACGAGTTCTATTCCCGCGAGGGG >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_2415nt ATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACG ATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGA AGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATAC TTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCA GAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAG AGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTG GAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATG GAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATT GATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTT GATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAA GCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGA GTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTT GAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAG GTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATC CTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAG GACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGAC GTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGC CAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATG GAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACG ATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACG GACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTAC ACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGA CAGATCTACGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCC ATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATG AAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAG GGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATT >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_2466nt ATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACG ATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGA AGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATAC TTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCA GAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAG AGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTG GAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATG GAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATT GATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTT GATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAA GCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGA GTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTT GAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAG GTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATC CTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAG GACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGAC GTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGC CAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATG GAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACG ATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACG GACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTAC ACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGGTCGGGGAGGATCCATCACACAGATCCCCATCCTCACCATGCCCAAC GACGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTACGTGGACAGACAGCTTCACAACAGACAGATC TACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTC TCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGAC CTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGAC CTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGCCGTGATCGACGAGTTCTATTCCCGCGAGGGG >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_2415nt ATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACG ATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGA AGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATAC TTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCA GAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAG AGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTG GAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATG GAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATT GATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTT GATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAA GCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGA GTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTT GAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAG GTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATC CTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAG GACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGAC GTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGC CAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATG GAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACG ATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACG GACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTAC ACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGA CAGATCTACGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCC ATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATG AAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAG GGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_3094nt AGGTCAGGGGCGTGGCGAAGGTCGCTGCTTTCCTGCTACAACGGGCCTACTTTAGCTAAAACAGAAACGTAAGGCCAGGACGGGTCACCC TTTGTGGGCCCCTGAAAAATACAAAACGAAGTTTGGAGAGAGTTGAAAGGCGTTTGGGCTGACCATGGAGATTTTTGTTTCCCACCCTCC TGCGAAAGCGCTCGCGCTGCCATTGGCTCTGGCTGAGGGCGAGTCCGGAACCTGTGCGCCGCGGAACTTTCGGCTCTGAAATCCAAGTTG CGCTGGGCGCATCTTTGCCGCGCGGTTTCCGGGCGGCTCCCTTCCCTTGCATGCTGCATTGTGTCGGGAGTTGCTGACAGCCATGGCGCC GCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACGATTCAAGA GGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGAAGCCCCTT GCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATACTTTCAGAA TGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCAGAGATAGA GGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAGAGAGCTGA AAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTGGAACAGCA GAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATGGAGGCCTA TTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATTGATTCTGA TGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTTGATCCAGT TGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAAGCAGAAGA ACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGAGTGACCTT TGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTTGAAAAAAG ACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAGGTGGCTGG CACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATCCTACGAAC TCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAGGACTTTCT GGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGACGTCATGAA CAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGCCAGGCGGG GCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATGGAGACAGC CAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACGATCGAGCG GATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACGGACATGAG TTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTACACAGACCT GGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGGTCGGGGAGGATCCATCACACAGATCCCCATCCTCACCATGCCCAACGACGATAT CACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTACGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCC CATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCA GCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTA CCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTG GAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGCCGTGATCGACGAGTTCTATTCCCGCGAGGGGGCGCTGCA GGACCTCGCGCCTGACACTGCGCTCTAGCCCCGCGCGCCGTGGCACCCCAACACCGGCAGGGAACCTACCCTCGGCTCCCGGGTCTCCCC TCCCTCGCCACCCCAACCAGCGGCTTCTGCGCCGCCCTCCGCCCTCCGCTGGCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTT CCCTCGCTCGATTCCTTTTCCCGCGCTCCATGCCTCCCCCTCGACTCCCGGTGCTGCGGAAGAACTGAAGGTTGCGATGCCTTACTCTGA >In-frame_MPHOSPH10_ENST00000244230_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_3047nt AGGTCAGGGGCGTGGCGAAGGTCGCTGCTTTCCTGCTACAACGGGCCTACTTTAGCTAAAACAGAAACGTAAGGCCAGGACGGGTCACCC TTTGTGGGCCCCTGAAAAATACAAAACGAAGTTTGGAGAGAGTTGAAAGGCGTTTGGGCTGACCATGGAGATTTTTGTTTCCCACCCTCC TGCGAAAGCGCTCGCGCTGCCATTGGCTCTGGCTGAGGGCGAGTCCGGAACCTGTGCGCCGCGGAACTTTCGGCTCTGAAATCCAAGTTG CGCTGGGCGCATCTTTGCCGCGCGGTTTCCGGGCGGCTCCCTTCCCTTGCATGCTGCATTGTGTCGGGAGTTGCTGACAGCCATGGCGCC GCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGGCAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACGATTCAAGA GGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTTTAATAAAATATTAGAGAATGGTAGGATCCATGGAAGCCCCTT GCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACAACTGGAATTGCAAAATGAACCAATTTTACAATACTTTCAGAA TGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGAGAGTGAAGAACAGGAACGTGAAGAGGATGGTTCAGAGATAGA GGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTCCGACATGGGTAATGATGATCCTGAAATGGGTGAGAGAGCTGA AAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGAGGATTCTGACCTTGACTTTGATATCAGCAAATTGGAACAGCA GAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCATAGTAGATGATAAATTCTTCAAACTCTCTGAAATGGAGGCCTA TTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGAGGAGGAGGAAGATATTGATTTTTTTGAAGATATTGATTCTGA TGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAAAAGTTCCAGAAATCTGAAATACAAAGATTTTTTTGATCCAGT TGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTCAAACAAAGAAGATGATGAAATTGCTGAAGAAGAAGCAGAAGA ACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGAAGACAATAAACAACATAAAGAAAGCTTGAAAAGAGTGACCTT TGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGTAAAGAAAAATTCTGATGAAGTTAAATCCTCCTTTGAAAAAAG ACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCCAGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAGGTGGCTGG CACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGCCAGGAAGACCACTTGCGAATTTACAGGGGACATCCTACGAAC TCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAAGCCCATTGACAAGGGGCCAGTGGTCATGGCGGAGGACTTTCT GGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGAGGAGATGATTCAGACGGGCATTTCTCCTATTGACGTCATGAA CAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCTCCCCCACAATGAGATTGCCGCTCAGATCTGCCGCCAGGCGGG GCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTTCGCCATCGTCTTTGCAGCCATGGGGGTGAACATGGAGACAGC CAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGTCTGCCTCTTCCTGAACTTGGCCAATGACCCCACGATCGAGCG GATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTACCAGTGTGAGAAGCATGTGCTGGTCATACTGACGGACATGAG TTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGTGCCTGGGCGCCGAGGGTTTCCTGGATATATGTACACAGACCT GGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTA CGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGGGGA AGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGT AGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCCCTA CGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGC CGTGATCGACGAGTTCTATTCCCGCGAGGGGGCGCTGCAGGACCTCGCGCCTGACACTGCGCTCTAGCCCCGCGCGCCGTGGCACCCCAA CACCGGCAGGGAACCTACCCTCGGCTCCCGGGTCTCCCCTCCCTCGCCACCCCAACCAGCGGCTTCTGCGCCGCCCTCCGCCCTCCGCTG GCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTTCCCTCGCTCGATTCCTTTTCCCGCGCTCCATGCCTCCCCCTCGACTCCCGG >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000234396_chr2_71185176_+_2776nt GCATGCTGCATTGTGTCGGGAGTTGCTGACAGCCATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGG CAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACGATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTT TAATAAAATATTAGAGAATGGTAGGATCCATGGAAGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACA ACTGGAATTGCAAAATGAACCAATTTTACAATACTTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGA GAGTGAAGAACAGGAACGTGAAGAGGATGGTTCAGAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTC CGACATGGGTAATGATGATCCTGAAATGGGTGAGAGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGA GGATTCTGACCTTGACTTTGATATCAGCAAATTGGAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCAT AGTAGATGATAAATTCTTCAAACTCTCTGAAATGGAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGA GGAGGAGGAAGATATTGATTTTTTTGAAGATATTGATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAA AAGTTCCAGAAATCTGAAATACAAAGATTTTTTTGATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTC AAACAAAGAAGATGATGAAATTGCTGAAGAAGAAGCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGA AGACAATAAACAACATAAAGAAAGCTTGAAAAGAGTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGT AAAGAAAAATTCTGATGAAGTTAAATCCTCCTTTGAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCC AGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAGGTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGC CAGGAAGACCACTTGCGAATTTACAGGGGACATCCTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAA GCCCATTGACAAGGGGCCAGTGGTCATGGCGGAGGACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGA GGAGATGATTCAGACGGGCATTTCTCCTATTGACGTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCT CCCCCACAATGAGATTGCCGCTCAGATCTGCCGCCAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTT CGCCATCGTCTTTGCAGCCATGGGGGTGAACATGGAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGT CTGCCTCTTCCTGAACTTGGCCAATGACCCCACGATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTA CCAGTGTGAGAAGCATGTGCTGGTCATACTGACGGACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGT GCCTGGGCGCCGAGGGTTTCCTGGATATATGTACACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGGTCGGGGAGGATC CATCACACAGATCCCCATCCTCACCATGCCCAACGACGATATCACCCACCCTATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGAT CTACGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGTGCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGG GGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGTACGCCTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGC AGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTACCTGGAATTCCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCC CTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCTGCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCA GGCCGTGATCGACGAGTTCTATTCCCGCGAGGGGGCGCTGCAGGACCTCGCGCCTGACACTGCGCTCTAGCCCCGCGCGCCGTGGCACCC CAACACCGGCAGGGAACCTACCCTCGGCTCCCGGGTCTCCCCTCCCTCGCCACCCCAACCAGCGGCTTCTGCGCCGCCCTCCGCCCTCCG CTGGCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTTCCCTCGCTCGATTCCTTTTCCCGCGCTCCATGCCTCCCCCTCGACTCC >In-frame_MPHOSPH10_ENST00000498451_chr2_71361927_+_ATP6V1B1_ENST00000412314_chr2_71185176_+_2729nt GCATGCTGCATTGTGTCGGGAGTTGCTGACAGCCATGGCGCCGCAGGTCTGGCGTCGACGGACCCTGGAGCGGTGTCTGACGGAAGTCGG CAAAGCCACGGGTCGGCCCGAGTGCTTCCTCACGATTCAAGAGGGATTGGCATCAAAGTTCACTTCTTTAACAAAAGTGCTTTATGACTT TAATAAAATATTAGAGAATGGTAGGATCCATGGAAGCCCCTTGCAAAAACTTGTGATAGAAAATTTTGATGATGAGCAGATTTGGCAACA ACTGGAATTGCAAAATGAACCAATTTTACAATACTTTCAGAATGCAGTTAGTGAAACAATTAATGATGAAGATATCAGTCTTCTCCCAGA GAGTGAAGAACAGGAACGTGAAGAGGATGGTTCAGAGATAGAGGCTGATGACAAGGAGGACCTAGAAGATTTAGAGGAGGAGGAAGTGTC CGACATGGGTAATGATGATCCTGAAATGGGTGAGAGAGCTGAAAACTCAAGCAAATCTGATCTGAGGAAAAGCCCCGTTTTCAGTGATGA GGATTCTGACCTTGACTTTGATATCAGCAAATTGGAACAGCAGAGCAAGGTGCAAAACAAAGGACAGGGAAAACCAAGAGAAAAGTCCAT AGTAGATGATAAATTCTTCAAACTCTCTGAAATGGAGGCCTATTTAGAAAACATAGAAAAAGAAGAGGAACGAAAAGATGATAATGATGA GGAGGAGGAAGATATTGATTTTTTTGAAGATATTGATTCTGATGAAGATGAAGGGGGACTGTTTGGAAGTAAAAAACTTAAGTCAGGTAA AAGTTCCAGAAATCTGAAATACAAAGATTTTTTTGATCCAGTTGAAAGTGATGAAGACATAACAAATGTTCATGATGATGAGCTGGATTC AAACAAAGAAGATGATGAAATTGCTGAAGAAGAAGCAGAAGAACTAAGTATTTCGGAAACGGATGAAGATGATGACCTTCAAGAAAATGA AGACAATAAACAACATAAAGAAAGCTTGAAAAGAGTGACCTTTGCTTTACCAGATGATGCGGAAACTGAAGATACAGGTGTTTTAAATGT AAAGAAAAATTCTGATGAAGTTAAATCCTCCTTTGAAAAAAGACAGGAAAAGTTTGCCCAGTATGCGGAGATCGTCCACTTCACCCTCCC AGATGGGACTCAGAGGAGCGGGCAGGTGCTTGAGGTGGCTGGCACCAAGGCGATTGTTCAGGTGTTTGAAGGGACATCAGGGATCGATGC CAGGAAGACCACTTGCGAATTTACAGGGGACATCCTACGAACTCCGGTGTCAGAGGACATGCTGGGTCGGGTTTTCAATGGCTCCGGCAA GCCCATTGACAAGGGGCCAGTGGTCATGGCGGAGGACTTTCTGGATATCAATGGCCAGCCCATCAACCCGCACTCCCGCATCTACCCCGA GGAGATGATTCAGACGGGCATTTCTCCTATTGACGTCATGAACAGCATTGCCCGCGGCCAGAAGATCCCCATCTTCTCAGCAGCCGGGCT CCCCCACAATGAGATTGCCGCTCAGATCTGCCGCCAGGCGGGGCTGGTGAAGAAGTCCAAGGCTGTGCTGGATTACCATGACGACAACTT CGCCATCGTCTTTGCAGCCATGGGGGTGAACATGGAGACAGCCAGATTCTTCAAGTCTGACTTTGAGCAGAATGGAACCATGGGGAACGT CTGCCTCTTCCTGAACTTGGCCAATGACCCCACGATCGAGCGGATCATCACCCCGCGCCTGGCGCTGACCACTGCTGAATTCCTTGCCTA CCAGTGTGAGAAGCATGTGCTGGTCATACTGACGGACATGAGTTCCTATGCAGAGGCCTTGCGGGAGGTCTCTGCTGCTAGAGAGGAGGT GCCTGGGCGCCGAGGGTTTCCTGGATATATGTACACAGACCTGGCCACCATCTACGAGCGGGCGGGCCGCGTGGAGGATATCACCCACCC TATCCCAGACTTGACGGGCTTCATCACAGAGGGACAGATCTACGTGGACAGACAGCTTCACAACAGACAGATCTACCCCCCCATCAACGT GCTCCCTTCCCTGTCGCGGCTGATGAAGTCAGCCATTGGGGAAGGCATGACAAGAAAGGACCATGGAGATGTCTCCAACCAGCTGTACGC CTGCTATGCCATCGGGAAGGACGTGCAGGCCATGAAGGCAGTAGTTGGGGAGGAGGCGCTCACCTCTGAGGACCTGCTCTACCTGGAATT CCTGCAGAAGTTTGAGAAGAACTTCATCAATCAGGGCCCCTACGAGAACCGCTCGGTGTTCGAGTCGCTGGACCTGGGCTGGAAGCTGCT GCGCATCTTCCCCAAGGAGATGCTGAAGCGCATTCCGCAGGCCGTGATCGACGAGTTCTATTCCCGCGAGGGGGCGCTGCAGGACCTCGC GCCTGACACTGCGCTCTAGCCCCGCGCGCCGTGGCACCCCAACACCGGCAGGGAACCTACCCTCGGCTCCCGGGTCTCCCCTCCCTCGCC ACCCCAACCAGCGGCTTCTGCGCCGCCCTCCGCCCTCCGCTGGCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTTCCCTCGCTC GATTCCTTTTCCCGCGCTCCATGCCTCCCCCTCGACTCCCGGTGCTGCGGAAGAACTGAAGGTTGCGATGCCTTACTCTGACGGGAGCAT |
Top |
FusionGenePPI for MPHOSPH10_ATP6V1B1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MPHOSPH10 | IMP3, IMP4, SIRT7, CSNK2A1, PPP1CA, RNF2, RPS2, RBM4B, DDX52, DDX56, DKC1, AATF, DDX18, EBNA1BP2, ESF1, FBL, FTSJ3, GLTSCR2, GTPBP4, IPO7, KRI1, NOP2, NOP56, NOP58, PWP2, RPS15A, TBL3, UTP18, UTP3, WDR36, NOL10, NOL6, RPS7, UTP14A, UTP15, SCARNA22, IFI16, DIEXF, DGCR8, ZNF2, RPL37A, FGF8, HIST1H1T, RRS1, ZC3HAV1, FGF3, SART3, FOXA1 | ATP6V1B1 | STX1A, ARL8B, ATP6V0D1, ATP6V1A, ATP6V0A1, ATP6V1B2, ATP6V1C1, ATP6V1D, ATP6V1E1, ATP6V1G1, ATP6V1H, BANF1, LAMTOR1, SLC35F6, CD63, CD9, CHMP1A, CHMP1B, CHMP2B, CHMP4B, CHMP5, CTSD, DNAJC13, DNAJC5, MYOF, FLOT1, FLOT2, FTH1, GBA, GGH, GNB1, IST1, LAMP1, LAMP2, MITD1, MYO1B, MYO1D, MYO3B, NCSTN, PKP4, PLBD1, RAB22A, RAB35, RALB, RRAS, S100A11, SCARB2, SERPINA3, STOM, STX12, STX8, TACSTD2, TFRC, TM9SF1, TMEM192, TMOD3, VAMP7, VAMP8, CHMP3, VTI1B, TCIRG1, HNRNPDL, TRMT1, SLC30A5, PIGS, VPS33B, MARC1, ZBED1, ABCC2, HNRNPU, ERGIC1, LIMA1, MRPL50, SLC25A3, ATP5C1, UBE2B, INTS2, SLC30A1, KDM1A, SUV39H1, ATP6V1E2, CCT6B, CCT2, DMXL1, ATP6V0A2, ATP6V1F, ATP6V1G2, ATP6V1C2, NCOA7, WDR7, SVIP, ATP6V0D2, CEP135, SOD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MPHOSPH10_ATP6V1B1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MPHOSPH10_ATP6V1B1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ATP6V1B1 | C0403554 | Renal Tubular Acidosis, Distal, with Progressive Nerve Deafness | 3 | CTD_human;UNIPROT |
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