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Fusion gene ID: 22123 |
FusionGeneSummary for MKS1_KSR1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MKS1_KSR1 | Fusion gene ID: 22123 | Hgene | Tgene | Gene symbol | MKS1 | KSR1 | Gene ID | 54903 | 8844 |
| Gene name | Meckel syndrome, type 1 | kinase suppressor of ras 1 | |
| Synonyms | BBS13|JBTS28|MES|MKS|POC12 | KSR|RSU2 | |
| Cytomap | 17q22 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | Meckel syndrome type 1 proteinPOC12 centriolar protein homolog | kinase suppressor of Ras 1 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NXB0 | Q8IVT5 | |
| Ensembl transtripts involved in fusion gene | ENST00000393119, ENST00000313863, ENST00000337050, ENST00000537529, ENST00000546108, | ENST00000509603, ENST00000319524, ENST00000268763, ENST00000398988, ENST00000581975, ENST00000582410, ENST00000578981, | |
| Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 10 X 7 X 5=350 |
| # samples | 3 | 9 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(9/350*10)=-1.95935801550265 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MKS1 [Title/Abstract] AND KSR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E2-A14V-01A | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000393119 | ENST00000509603 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| In-frame | ENST00000393119 | ENST00000319524 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000393119 | ENST00000268763 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000393119 | ENST00000398988 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000393119 | ENST00000581975 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000393119 | ENST00000582410 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000393119 | ENST00000578981 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| Frame-shift | ENST00000313863 | ENST00000509603 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| Frame-shift | ENST00000313863 | ENST00000319524 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000313863 | ENST00000268763 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000313863 | ENST00000398988 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000313863 | ENST00000581975 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000313863 | ENST00000582410 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000313863 | ENST00000578981 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| In-frame | ENST00000337050 | ENST00000509603 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| In-frame | ENST00000337050 | ENST00000319524 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000337050 | ENST00000268763 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000337050 | ENST00000398988 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000337050 | ENST00000581975 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000337050 | ENST00000582410 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000337050 | ENST00000578981 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| In-frame | ENST00000537529 | ENST00000509603 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| In-frame | ENST00000537529 | ENST00000319524 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000537529 | ENST00000268763 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-5UTR | ENST00000537529 | ENST00000398988 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000537529 | ENST00000581975 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000537529 | ENST00000582410 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5CDS-intron | ENST00000537529 | ENST00000578981 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-3CDS | ENST00000546108 | ENST00000509603 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-3CDS | ENST00000546108 | ENST00000319524 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-5UTR | ENST00000546108 | ENST00000268763 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-5UTR | ENST00000546108 | ENST00000398988 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-intron | ENST00000546108 | ENST00000581975 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-intron | ENST00000546108 | ENST00000582410 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
| 5UTR-intron | ENST00000546108 | ENST00000578981 | MKS1 | chr17 | 56294027 | - | KSR1 | chr17 | 25904518 | + |
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FusionProtFeatures for MKS1_KSR1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MKS1 | KSR1 |
| Component of the tectonic-like complex, a complexlocalized at the transition zone of primary cilia and acting as abarrier that prevents diffusion of transmembrane proteins betweenthe cilia and plasma membranes. Involved in centrosome migrationto the apical cell surface during early ciliogenesis. Required forciliary structure and function, including a role in regulatinglength and appropriate number through modulating centrosomeduplication. Required for cell branching morphology.{ECO:0000269|PubMed:17185389, ECO:0000269|PubMed:19515853,ECO:0000269|PubMed:26490104}. | Scaffolding protein that is part of a multiproteinsignaling complex. Promotes phosphorylation of Raf family membersand activation of downstream MAP kinases. Promotes activation ofMAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does nothave kinase activity by itself. {ECO:0000250|UniProtKB:Q61097}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >KSR1 | chr17:56294027 | chr17:25904518 | ENST00000268763 | + | 2 | 22 | 17_21 | -13 | 787 | Compositional bias | Note=Poly-Gly |
| Tgene | >KSR1 | chr17:56294027 | chr17:25904518 | ENST00000268763 | + | 2 | 22 | 289_292 | -13 | 787 | Compositional bias | Note=Poly-Pro |
| Tgene | >KSR1 | chr17:56294027 | chr17:25904518 | ENST00000268763 | + | 2 | 22 | 613_883 | -13 | 787 | Domain | Protein kinase |
| Tgene | >KSR1 | chr17:56294027 | chr17:25904518 | ENST00000268763 | + | 2 | 22 | 1_172 | -13 | 787 | Region | Mediates association with membranes |
| Tgene | >KSR1 | chr17:56294027 | chr17:25904518 | ENST00000268763 | + | 2 | 22 | 347_391 | -13 | 787 | Zinc finger | Phorbol-ester/DAG-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MKS1 | chr17:56294027 | chr17:25904518 | ENST00000393119 | - | 3 | 18 | 311_439 | 87 | 560 | Domain | B9 |
| Hgene | >MKS1 | chr17:56294027 | chr17:25904518 | ENST00000537529 | - | 3 | 18 | 311_439 | 77 | 550 | Domain | B9 |
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FusionGeneSequence for MKS1_KSR1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_840aa MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIP RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGR AGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLT RSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLP LTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFN FPAAYFIHHRQQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQT SVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFC KGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYL APEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPS >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_887aa MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIP RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGR AGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLT RSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLP LTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFN FPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDE VDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHE NVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGIS GVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVS >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_840aa MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIP RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGR AGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLT RSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLP LTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFN FPAAYFIHHRQQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQT SVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFC KGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYL APEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPS >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_887aa MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIP RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGR AGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLT RSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLP LTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFN FPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDE VDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHE NVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGIS GVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVS >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_830aa MAVPVSSFAQRTRSRFRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIPRDLTLDALLE MNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRS ISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLG NRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESV PSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHR QQFIFPDISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIP FEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVR DPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTP GKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEK >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_877aa MAVPVSSFAQRTRSRFRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQEIPRDLTLDALLE MNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRS ISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLG NRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESV PSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHR QQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRP WRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACM NPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRREN QLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2520nt ATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTG CAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAG CCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCC CGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGT GGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGAT GCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGA GCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTC TCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTG CGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACC CGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATG GTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATG ATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCA CTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCC AAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCC TCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAAC TTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCT GCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCA GAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACC AGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGC GGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATG AACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGC AAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAG GGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACA GACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTG GCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACT GTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATG AAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGC TTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGAGCTG >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_2661nt ATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTG CAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAG CCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCC CGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGT GGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGAT GCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGA GCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTC TCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTG CGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACC CGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATG GTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATG ATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCA CTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCC AAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCC TCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAAC TTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCTCCTTATTGCA GAAAGTTTAAAGGAAAACGCTTTCAACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGAC CAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAG GTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGAC ATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCC ATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAG AACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTT GTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAG GGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCA GGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATG ACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGA GACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGC TTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTG GAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGTTGTACCCCGG >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2520nt ATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTG CAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAG CCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCC CGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGT GGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGAT GCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGA GCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTC TCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTG CGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACC CGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATG GTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATG ATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCA CTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCC AAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCC TCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAAC TTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCT GCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCA GAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACC AGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGC GGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATG AACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGC AAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAG GGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACA GACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTG GCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACT GTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATG AAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGC TTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGAGCTG >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_2661nt ATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTG CAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAG CCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCC CGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGT GGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGAT GCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGA GCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTC TCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTG CGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACC CGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATG GTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATG ATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCA CTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCC AAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCC TCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAAC TTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCTCCTTATTGCA GAAAGTTTAAAGGAAAACGCTTTCAACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGAC CAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAG GTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGAC ATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCC ATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAG AACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTT GTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAG GGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCA GGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATG ACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGA GACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGC TTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTG GAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGTTGTACCCCGG >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2490nt ATGGCTGTGCCAGTTTCCTCATTTGCACAGCGCACGAGGTCCCGCTTTCGAGTCCACCTGCAAAGAATCACATCAAGCAACTTTCTTCAT TATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGAGGAA GACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCTGGAG ATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTGCCTG CGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCCTTCC ACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACGCTCC ATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGCCAGC GGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACCACGG ACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCTGGGG AACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATCGGGCTGTCGGTGACG CACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTGCAGG TTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATCTGTC CCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCCTCCG GCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTCCCGACATCATCCAAC CCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCATAGA CAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCG AAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGAC GACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACATCCCC TTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGC CTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTG GTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGTGAGG GACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAGGGCATC GTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTG GTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCC GGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGACTGG CCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGG AAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAA >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_2631nt ATGGCTGTGCCAGTTTCCTCATTTGCACAGCGCACGAGGTCCCGCTTTCGAGTCCACCTGCAAAGAATCACATCAAGCAACTTTCTTCAT TATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGAGGAA GACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCTGGAG ATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTGCCTG CGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCCTTCC ACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACGCTCC ATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGCCAGC GGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACCACGG ACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCTGGGG AACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATCGGGCTGTCGGTGACG CACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTGCAGG TTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATCTGTC CCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCCTCCG GCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTCCCGACATCATCCAAC CCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCATAGA CAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCTCCTTATTGCAGAAAGTTTAAAGGAAAACGCTTTCAACATT TCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCAC GAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCC TGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAG CCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAAC CAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATG AACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATC AACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAG AACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAAC CAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCA TTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAG GCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCG GCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCGGCTC TCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGTTGTACCCCGGTTTGAAAGGTTTGGCTTGGGCGTCCTGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2595nt CCGATCCAGCGTCTCCGTTGCCAGGAAAACAGAGCGGCGCGCTTTCCGGCGCAGTCGCGGCGCGTCGCAGCTGTCATGGCGGAGACCGTC TGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTGCAAAGAATCACATCA AGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGA CACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTG GATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTAT GCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGT GGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCC CAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATT CCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAG CTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCAT GAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATC GGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAG TGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGG AGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAG AAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTC CCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTAC TTCATTCATCATAGACAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGG CTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGAT GAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAG GAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGC GAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACG CGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTG CACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTT CATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTT GGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTA CGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTG CAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACT TCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATG >In-frame_MKS1_ENST00000393119_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_3035nt CCGATCCAGCGTCTCCGTTGCCAGGAAAACAGAGCGGCGCGCTTTCCGGCGCAGTCGCGGCGCGTCGCAGCTGTCATGGCGGAGACCGTC TGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCGAGTCCACCTGCAAAGAATCACATCA AGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGA CACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTG GATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTAT GCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGT GGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCC CAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATT CCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAG CTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCAT GAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATC GGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAG TGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGG AGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAG AAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTC CCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTAC TTCATTCATCATAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCTCCTTATTGCAGAAAGTTTAAAGGAA AACGCTTTCAACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGAT GTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCG AGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAG GTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAG ATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTC ATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAG ACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAA GATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAG GGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGAC GAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAG AACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTC AGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAG CTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGTTGTACCCCGGTTTGAAAGGTTTGGC TTGGGCGTCCTGGAGTCCAGTAATCCAAAGATGTAGCCAGCCATATGGTTTTTCGCTGCTGATCTCTTTCTTTTTAAAATGTGTTTCTGA AACATCCCAACAACCACCACGACAAAAAAACACTGCCTGCCCAGCGCTGCAAACCAGGAGCACACGTCCTAGATTCAGACTGTTGGCCAT AAACCCCACTCGGGAGATGGAGCTGCACCTGCTATTTCTTAAAATGACACCACCAACAACCAAACCTGTCATGACAGACAGCAAATGTTT >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2530nt CGCAGCTGTCATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCG AGTCCACCTGCAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTT TAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCA GGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGG GGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAG TTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCA GCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAG TGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCAC ACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCC CACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATC CCCACAGATGGTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCA GAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATC CTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGG AACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTC CACACCCTCCTCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAG CAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCT CCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGC TGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGC CAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCG GGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAA AGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCAC CAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGA GATCATCAAGGGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGT GGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCT GTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGC ATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGG GGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGA GAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTC >In-frame_MKS1_ENST00000337050_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_2970nt CGCAGCTGTCATGGCGGAGACCGTCTGGAGCACTGACACCGGGGAGGCAGTGTATCGCTCCCGGGACCCCGTGCGCAACTTGCGCCTCCG AGTCCACCTGCAAAGAATCACATCAAGCAACTTTCTTCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTT TAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGAGGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCA GGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCTGGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGG GGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAG TTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCA GCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAG TGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCAC ACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCC CACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATC CCCACAGATGGTACGGAGGGATATCGGGCTGTCGGTGACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCA GAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATC CTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGG AACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTC CACACCCTCCTCACCGGCGCCCTTCCCGACATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAG CAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCT CCTTATTGCAGAAAGTTTAAAGGAAAACGCTTTCAACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCG GCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGA TGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCA GGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGG CGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGAC GCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTT GCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCT TCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTT TGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGT ACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCT GCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGAC TTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGAT GGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGT TGTACCCCGGTTTGAAAGGTTTGGCTTGGGCGTCCTGGAGTCCAGTAATCCAAAGATGTAGCCAGCCATATGGTTTTTCGCTGCTGATCT CTTTCTTTTTAAAATGTGTTTCTGAAACATCCCAACAACCACCACGACAAAAAAACACTGCCTGCCCAGCGCTGCAAACCAGGAGCACAC GTCCTAGATTCAGACTGTTGGCCATAAACCCCACTCGGGAGATGGAGCTGCACCTGCTATTTCTTAAAATGACACCACCAACAACCAAAC CTGTCATGACAGACAGCAAATGTTTACACGTATATTTCTCCTGAGTGAACCTGATGTTTTACAATAGGTAATAATAAAAACAGTCTGTGC >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000509603_chr17_25904518_+_2584nt AGTGTGGCATGGTGGAAAAGGTAGAGGGCGAAGACTCAGGCCACCTGGTCCCCGTCATCATTTCTGCATCTATCTGTCTATATGAAGTGG GCTGATGGCTGTGCCAGTTTCCTCATTTGCACAGCGCACGAGGTCCCGCTTTCGAGTCCACCTGCAAAGAATCACATCAAGCAACTTTCT TCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGA GGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCT GGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTG CCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCC TTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACG CTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGC CAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACC ACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCT GGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATCGGGCTGTCGGT GACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTG CAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATC TGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCC TCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTCCCGACATCATC CAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCA TAGACAGCAGTTTATCTTTCCAGACATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCA GCCGAAAGCAGATGTGTTGGAAGCTCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGT GGACGACTTGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACAT CCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCAT TCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAA CGTGGTGCTCTTCATGGGGGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGT GAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAGGG CATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGG CGTGGTCCGAGAGGGACGGCGTGAGAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGAC CCCCGGGAAGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGA CTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTT GGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGA >In-frame_MKS1_ENST00000537529_chr17_56294027_-_KSR1_ENST00000319524_chr17_25904518_+_3024nt AGTGTGGCATGGTGGAAAAGGTAGAGGGCGAAGACTCAGGCCACCTGGTCCCCGTCATCATTTCTGCATCTATCTGTCTATATGAAGTGG GCTGATGGCTGTGCCAGTTTCCTCATTTGCACAGCGCACGAGGTCCCGCTTTCGAGTCCACCTGCAAAGAATCACATCAAGCAACTTTCT TCATTATCAGCCTGCTGCCGAGCTCGGGAAGGACCTCATAGACTTGGCCACTTTTAGGCCTCAGCCAACTGCCAGTGGACACCGCCCAGA GGAAGACGAAGAGGAGGAGATTGTGATTGGGTGGCAGGAGAAGCTCTTTAGCCAGGAGATCCCCCGAGACCTCACGCTGGATGCCCTGCT GGAGATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGCAGTATGCCCTCACCTG CCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAGTTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCC TTCCACGGACACCCTCTCAGCAGCCAGCCTGCCCTGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACG CTCCATCTCCGTGTCAGCTCTGCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATTCCCCTGCACGC CAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTGCGACGGCACACCAAGCTGAAGCCACC ACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGCCCAGCTTCCCCACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCT GGGGAACCGCATTGATGACGTCTCCTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATCGGGCTGTCGGT GACGCACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAGTGAAGTGCAAGCATTG CAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATCCTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATC TGTCCCCTCGGACATCAACAACCCGGTGGACAGAGCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCC TCCGGCCATGAATCACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTCCCGACATCATC CAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAACTTCCCAGCTGCCTACTTCATTCATCA TAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCTGGAAATGCCTCCTTATTGCAGAAAGTTTAAAGGAAAACGCTTTCAA CATTTCAGCCTTTGCACACGCAGCCCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGC TCACGAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGACGACTTGCCGAGCTCTCGCCG GCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCAGGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGG CGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTGCACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCA CAACCAGGACCACCTGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGGGGCCTG CATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTTGTGAGGGACCCCAAGACGTCTCTGGA CATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCATGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATC TAAGAACGTCTTCTATGACAACGGCAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGA GAACCAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCCGGGAAGGACGAGGATCAGCT GCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCTGCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGC AGAGGCATCCATCTGGCAGATTGGAAGCGGGGAAGGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCT GTCGGCCTGCTGGGCTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAACCGGCG GCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGACATTAACAGCAGCAAAGTTGTACCCCGGTTTGAAAGGTTTGGCTTGGGCGTCCT GGAGTCCAGTAATCCAAAGATGTAGCCAGCCATATGGTTTTTCGCTGCTGATCTCTTTCTTTTTAAAATGTGTTTCTGAAACATCCCAAC AACCACCACGACAAAAAAACACTGCCTGCCCAGCGCTGCAAACCAGGAGCACACGTCCTAGATTCAGACTGTTGGCCATAAACCCCACTC GGGAGATGGAGCTGCACCTGCTATTTCTTAAAATGACACCACCAACAACCAAACCTGTCATGACAGACAGCAAATGTTTACACGTATATT |
Top |
FusionGenePPI for MKS1_KSR1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MKS1 | DDX24, SHMT2, KLK5, TMEM231, ENPP6, LIPH, THBS3, B9D2, AP3M1, ARFGAP3, B9D1, R3HCC1L, CAD, CC2D1A, CCT2, CCT3, CCT4, CCT5, CCT6A, CCT7, COPA, COPB1, COPZ1, DBT, DNAJC11, ECH1, EGLN1, FKBP4, GLMN, HAUS7, HAUS8, KIAA0355, MB21D2, NUDC, NUDCD2, NUDCD3, PDCL3, PIH1D1, RELA, RFC5, RPAP3, RRM2, SAMD4B, SUGT1, TBC1D2B, TCP1, TNRC6B, UNC45A, UXT, YTHDF1, AIP, BAG2, DNAJA1, DNAJA2, DNAJC7, LRRC49, TPGS1, TUBA8, TCTN2, CC2D2A, TMEM17, XPO1, SYNE2, TCTN1, DOCK5, LGALS7, PDDC1, C6orf141, CDC16, ARPC5, RAD51D, IL17RA, SSH3, ADAMTS4, ENPP7, PSG8, TSPYL6, PPIAL4G, CRYBA4, SNX21, RCCD1, TRIM35, POSTN | KSR1 | MAP2K1, BRAF, BRAP, KSR1, MARK3, RAF1, LSP1, HSP90AA1, YWHAE, YWHAB, SDF4, SKAP1, PRMT2, XPO1, VPRBP, NF2, PJA2, KCTD3, KIF13B, ZBTB21, GIGYF1, CGN, LRFN1, DENND1A, SH3PXD2A, RTKN, DENND4C, MAST3, SRGAP2, EIF4E2, SIPA1L1, PPM1H, LPIN3, LIMA1, MAGI1, TESK2, DCLK1, ZNF638, MAPKAP1, NF1, HDAC4, CBY1, SH3RF3, SRSF12, CDC25C, SYDE1, AGAP1, NADK, GIGYF2, CDC25B, CDK16, TANC2, CAMSAP2, PTPN13, RALGPS2, FAM110B, USP21, KIAA1804, RASAL2, TIAM1, ANKRD34A, FAM53C, PHLDB2, RPTOR, PLEKHA7, OSBPL6, KIF1C, MELK, NAV1, DENND4A, FAM110A, GAB2, STARD13, PTPN14, DEPDC1B, HDAC7, CWC25, INPP5E, LARP1, RAB11FIP2, PLEKHA5, MTFR1L, MLLT4, CHEK1, KIF1B, CSNK1A1, TBC1D25, EDC3, HDAC5, TBC1D1, DACT3, PANK2, REEP3, CRTC2, CRTC3, MICALL1, SH3BP4, BAIAP2, FGD6 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MKS1_KSR1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MKS1_KSR1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MKS1 | C0752166 | Bardet-Biedl Syndrome | 1 | CTD_human;ORPHANET |
| Hgene | MKS1 | C2673873 | BARDET-BIEDL SYNDROME 13 | 1 | UNIPROT |
| Hgene | MKS1 | C3714506 | Meckel syndrome type 1 | 1 | CTD_human;UNIPROT |
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