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Fusion gene ID: 22100 |
FusionGeneSummary for MKLN1_IMMP2L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MKLN1_IMMP2L | Fusion gene ID: 22100 | Hgene | Tgene | Gene symbol | MKLN1 | IMMP2L | Gene ID | 4289 | 83943 |
| Gene name | muskelin 1 | inner mitochondrial membrane peptidase subunit 2 | |
| Synonyms | TWA2 | IMMP2L-IT1|IMP2|IMP2-LIKE | |
| Cytomap | 7q32.3 | 7q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | muskelinmuskelin 1, intracellular mediator containing kelch motifs | mitochondrial inner membrane protease subunit 2IMP2 inner mitochondrial membrane peptidase-likeIMP2 inner mitochondrial membrane protease-likeinner mitochondrial membrane peptidase 2 like | |
| Modification date | 20180522 | 20180526 | |
| UniProtAcc | Q9UL63 | Q96T52 | |
| Ensembl transtripts involved in fusion gene | ENST00000421797, ENST00000429546, ENST00000352689, ENST00000498778, | ENST00000405709, ENST00000331762, ENST00000452895, ENST00000415362, ENST00000447215, ENST00000437687, ENST00000489381, ENST00000450877, | |
| Fusion gene scores | * DoF score | 9 X 9 X 6=486 | 15 X 7 X 10=1050 |
| # samples | 9 | 15 | |
| ** MAII score | log2(9/486*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/1050*10)=-2.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MKLN1 [Title/Abstract] AND IMMP2L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-38-4631-01A | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000421797 | ENST00000405709 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000421797 | ENST00000331762 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000421797 | ENST00000452895 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000421797 | ENST00000415362 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000421797 | ENST00000447215 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000421797 | ENST00000437687 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000421797 | ENST00000489381 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000421797 | ENST00000450877 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000429546 | ENST00000405709 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000429546 | ENST00000331762 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000429546 | ENST00000452895 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000429546 | ENST00000415362 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000429546 | ENST00000447215 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000429546 | ENST00000437687 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000429546 | ENST00000489381 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000429546 | ENST00000450877 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| Frame-shift | ENST00000352689 | ENST00000405709 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000352689 | ENST00000331762 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000352689 | ENST00000452895 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000352689 | ENST00000415362 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000352689 | ENST00000447215 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000352689 | ENST00000437687 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000352689 | ENST00000489381 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000352689 | ENST00000450877 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000498778 | ENST00000405709 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000498778 | ENST00000331762 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000498778 | ENST00000452895 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000498778 | ENST00000415362 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000498778 | ENST00000447215 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000498778 | ENST00000437687 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000498778 | ENST00000489381 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000498778 | ENST00000450877 | MKLN1 | chr7 | 131130662 | + | IMMP2L | chr7 | 110303777 | - |
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FusionProtFeatures for MKLN1_IMMP2L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MKLN1 | IMMP2L |
| Acts as a mediator of cell spreading and cytoskeletalresponses to the extracellular matrix component THBS1.{ECO:0000250|UniProtKB:O89050}. | Catalyzes the removal of transit peptides required forthe targeting of proteins from the mitochondrial matrix, acrossthe inner membrane, into the inter-membrane space. Known toprocess the nuclear encoded protein DIABLO.{ECO:0000269|PubMed:15814844}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MKLN1_IMMP2L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_456aa MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLK HFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRG GHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFY RYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPED IQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRALTS >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_456aa MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLK HFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRG GHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFY RYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPED IQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRALTS >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_456aa MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLK HFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRG GHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFY RYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPED IQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRALTS >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_548aa MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVF GGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLC LKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGM RGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSD FYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGP EDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRAL >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_548aa MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVF GGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLC LKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGM RGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSD FYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGP EDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRAL >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_548aa MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVF GGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLC LKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGM RGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSD FYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGP EDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRALAEIGICSSSRAL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_1369nt ATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGAT GAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTT AGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAA CACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATT CATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATC AGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGA GGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCG TACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGC ATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTAT CGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATG TGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAA CCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGAC ATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTG AATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGG ACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGT >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_1369nt ATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGAT GAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTT AGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAA CACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATT CATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATC AGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGA GGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCG TACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGC ATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTAT CGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATG TGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAA CCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGAC ATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTG AATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGG ACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGT >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_1369nt ATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGAT GAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTT AGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAA CACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATT CATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATC AGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGA GGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCG TACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGC ATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTAT CGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATG TGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAA CCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGAC ATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTG AATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGG ACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGT >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_1645nt ATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCCCTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTAC CTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTA AAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTT GGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAA ATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTT GAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGC CTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACA GATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAG TATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATG AGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTC TGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAA ATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGAC TTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCAT CAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCC AGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCT GAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACC TATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTC CCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTT >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_1645nt ATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCCCTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTAC CTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTA AAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTT GGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAA ATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTT GAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGC CTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACA GATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAG TATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATG AGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTC TGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAA ATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGAC TTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCAT CAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCC AGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCT GAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACC TATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTC CCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTT >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_1645nt ATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCCCTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTAC CTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTA AAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTT GGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAA ATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTT GAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGC CTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACA GATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAG TATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATG AGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTC TGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAA ATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGAC TTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCAT CAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCC AGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCT GAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACC TATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTC CCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_2329nt AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC CAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAG TTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGA GAAATATTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTATTAAATGGCACCTGATTTTGTGT TAAATTTTAGTTCCCTGTTGTTTAATGCCCCCAAAATATGCAGACCTTTGGGAATATAAAAATATTGCACCCACATGTCTTAATGGGGCT GAATTTCAGATTATTTGTTACATATACTTATTATATTGATTGTTGGGTTTTGATTTTGGTGCTTGCTGCTGAAATAAATTGAAAATTAAT ATTCAATAAAAATGATGTATTTGTCACTTGCTGTTAAGGTAGAACAAGAAGGAACACATATTATACACATAATGATGGGAATTACATTGT >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_1967nt AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC CAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAG TTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGA >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_1781nt AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000331762_chr7_110303777_-_2233nt GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC GCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAGTTGCTG GCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGAGAAATA TTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTATTAAATGGCACCTGATTTTGTGTTAAATT TTAGTTCCCTGTTGTTTAATGCCCCCAAAATATGCAGACCTTTGGGAATATAAAAATATTGCACCCACATGTCTTAATGGGGCTGAATTT CAGATTATTTGTTACATATACTTATTATATTGATTGTTGGGTTTTGATTTTGGTGCTTGCTGCTGAAATAAATTGAAAATTAATATTCAA TAAAAATGATGTATTTGTCACTTGCTGTTAAGGTAGAACAAGAAGGAACACATATTATACACATAATGATGGGAATTACATTGTGATTTG >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000452895_chr7_110303777_-_1871nt GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC GCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAGTTGCTG GCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGAGAAATA >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_IMMP2L_ENST00000415362_chr7_110303777_-_1685nt GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC |
Top |
FusionGenePPI for MKLN1_IMMP2L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MKLN1 | RNPS1, MYC, RANBP9, ELAVL1, MKLN1, MAEA, GID8, RMND5A, SOX2, PTGER3, GDNF, GLIPR1L2, MMP7, SFRP2, TDGF1, GGH, MRPL4, GPS2, NR1H3, HLA-DPB1, ADCYAP1, PRG2, IFI30, UNK, DYNC1H1, BMP1, PRG3, INSL6, PIGT, CCDC120, TIGD5, SUCLA2, NFATC1, LILRB4, CARKD, IKZF1, C4orf27, TLE4, ARMC8, ZMYND19, GID4, HTRA2, WDR26, PMFBP1, AAMP, MMADHC, HSPBP1, LONP1, RSPH10B, NDUFS2, SOAT1, RMND5B, YPEL5, RANBP10, RAB8A, TRIM25 | IMMP2L | HNRNPD |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MKLN1_IMMP2L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MKLN1_IMMP2L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | IMMP2L | C0004352 | Autistic Disorder | 1 | CTD_human |
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