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Fusion gene ID: 22098 |
FusionGeneSummary for MKLN1_EXOC4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MKLN1_EXOC4 | Fusion gene ID: 22098 | Hgene | Tgene | Gene symbol | MKLN1 | EXOC4 | Gene ID | 4289 | 60412 |
| Gene name | muskelin 1 | exocyst complex component 4 | |
| Synonyms | TWA2 | SEC8|SEC8L1|Sec8p | |
| Cytomap | 7q32.3 | 7q33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | muskelinmuskelin 1, intracellular mediator containing kelch motifs | exocyst complex component 4SEC8-like 1exocyst complex component Sec8 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9UL63 | Q96A65 | |
| Ensembl transtripts involved in fusion gene | ENST00000421797, ENST00000429546, ENST00000352689, ENST00000498778, | ENST00000253861, ENST00000539845, ENST00000393161, ENST00000545148, ENST00000460346, ENST00000541309, | |
| Fusion gene scores | * DoF score | 9 X 9 X 6=486 | 15 X 12 X 7=1260 |
| # samples | 9 | 15 | |
| ** MAII score | log2(9/486*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/1260*10)=-3.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MKLN1 [Title/Abstract] AND EXOC4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-G4-6315-01A | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000421797 | ENST00000253861 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| In-frame | ENST00000421797 | ENST00000539845 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000421797 | ENST00000393161 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000421797 | ENST00000545148 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000421797 | ENST00000460346 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000421797 | ENST00000541309 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-3CDS | ENST00000429546 | ENST00000253861 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-3CDS | ENST00000429546 | ENST00000539845 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000429546 | ENST00000393161 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000429546 | ENST00000545148 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000429546 | ENST00000460346 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000429546 | ENST00000541309 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| In-frame | ENST00000352689 | ENST00000253861 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| In-frame | ENST00000352689 | ENST00000539845 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000352689 | ENST00000393161 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000352689 | ENST00000545148 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000352689 | ENST00000460346 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| 5CDS-intron | ENST00000352689 | ENST00000541309 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-3CDS | ENST00000498778 | ENST00000253861 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-3CDS | ENST00000498778 | ENST00000539845 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000498778 | ENST00000393161 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000498778 | ENST00000545148 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000498778 | ENST00000460346 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
| intron-intron | ENST00000498778 | ENST00000541309 | MKLN1 | chr7 | 131130662 | + | EXOC4 | chr7 | 133682245 | + |
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FusionProtFeatures for MKLN1_EXOC4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MKLN1 | EXOC4 |
| Acts as a mediator of cell spreading and cytoskeletalresponses to the extracellular matrix component THBS1.{ECO:0000250|UniProtKB:O89050}. | Component of the exocyst complex involved in the dockingof exocytic vesicles with fusion sites on the plasma membrane.{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 172_204 | 508 | 736 | Domain | LisH |
| Hgene | MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 206_258 | 508 | 736 | Domain | CTLH |
| Hgene | MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 284_330 | 508 | 736 | Repeat | Note=Kelch 1 |
| Hgene | MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 339_391 | 508 | 736 | Repeat | Note=Kelch 2 |
| Hgene | MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 408_458 | 508 | 736 | Repeat | Note=Kelch 3 |
| Tgene | >EXOC4 | chr7:131130662 | chr7:133682245 | ENST00000393161 | + | 0 | 10 | 32_114 | -10 | 474 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 469_515 | 508 | 736 | Repeat | Note=Kelch 4 |
| Hgene | >MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 526_578 | 508 | 736 | Repeat | Note=Kelch 5 |
| Hgene | >MKLN1 | chr7:131130662 | chr7:133682245 | ENST00000352689 | + | 12 | 18 | 597_651 | 508 | 736 | Repeat | Note=Kelch 6 |
| Tgene | EXOC4 | chr7:131130662 | chr7:133682245 | ENST00000253861 | + | 13 | 18 | 32_114 | 735 | 975 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for MKLN1_EXOC4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_656aa MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLK HFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRG GHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFY RYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPED IQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQD MADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYF RRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRL >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_656aa MNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLK HFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRG GHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFY RYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPED IQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQD MADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYF RRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRL >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_748aa MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVF GGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLC LKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGM RGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSD FYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGP EDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_748aa MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVF GGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLC LKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGM RGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSD FYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGP EDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVLSPAQDSHTNTDLPPVSEQIMQTLSELAKSF QDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQ YFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_1968nt ATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGAT GAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTT AGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAA CACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATT CATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATC AGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGA GGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCG TACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGC ATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTAT CGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATG TGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAA CCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGAC ATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTG AATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCT GCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGAT ATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTAT GCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGC GCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTC AGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAG GCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAG TACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTG >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_1968nt ATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGAT GAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTT AGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAA CACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATT CATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATC AGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGA GGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCG TACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGC ATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTAT CGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATG TGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAA CCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGAC ATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTG AATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCT GCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGAT ATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTAT GCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGC GCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTC AGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAG GCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAG TACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTG >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_2244nt ATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCCCTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTAC CTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTA AAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTT GGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAA ATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTT GAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGC CTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACA GATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAG TATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATG AGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTC TGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAA ATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGAC TTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCAT CAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCC AGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCT GAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACC TATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTT TCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTC CAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGG AACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCC ATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAG TACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCG CGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGT GTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACG >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_2244nt ATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCCCTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTAC CTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTA AAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTT GGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAA ATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTT GAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGC CTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACA GATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAG TATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATG AGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTC TGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAA ATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGAC TTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCAT CAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCC AGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCT GAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACC TATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTT TCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTC CAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGG AACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCC ATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAG TACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCG CGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGT GTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_3611nt AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGT GTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGT GAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCC CCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGA AGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAG GAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCT TTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCT GCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCAT CAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTT TTTCCTTGGTATGTTATTGAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTC TGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACG GGACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTC AATATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTAT TACATAAACAGTAGGGTTTTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTG CCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAG TCTTTTGATCCCAGTCCCTGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTG CTGTATAAAAACCAAGAGCCAGACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCC TAATTTCTGAGAGAATAATGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCT GAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCC CCCGCAATGTGGGCACTTACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAG GTCATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACA GTGATGCCTCACACCCTGAAGGTGGGGGATTTTGTACCTGTTTGTACAACTTTGGTCTTGATGGGAAAAATGGAGAATTAAAAAGTGTTT >In-frame_MKLN1_ENST00000421797_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_2439nt AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGT GTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGT GAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCC CCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGA AGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAG GAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCT TTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCT GCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCAT CAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTT >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000253861_chr7_133682245_+_3515nt GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT AATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGA GCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGT TCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGT GGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCT GGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACAT TTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAA CACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCG CAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCA AGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCT TGGTATGTTATTGAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTT TGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTA GGGTGGGATAGGGAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATA TATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATA AACAGTAGGGTTTTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAA TCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTT GATCCCAGTCCCTGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTAT AAAAACCAAGAGCCAGACAATTAGACAACTATGGAGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTT CTGAGAGAATAATGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTC AGCTGAATGCAGGGAAGATGGGACAGAGTGACATTTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCA ATGTGGGCACTTACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATA GAAGGCAGCAATGCACTGACTGGGCCACATCTTGAAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATG CCTCACACCCTGAAGGTGGGGGATTTTGTACCTGTTTGTACAACTTTGGTCTTGATGGGAAAAATGGAGAATTAAAAAGTGTTTTGAGAA >In-frame_MKLN1_ENST00000352689_chr7_131130662_+_EXOC4_ENST00000539845_chr7_133682245_+_2343nt GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT AATATCAGATGGCACCAAGAAAGACTCTGGGATGGTGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGA GCAGATCATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGT TCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGT GGTCAAGCTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCT GGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACAT TTTTGTTCTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAA CACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCG CAGCCAGACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCA AGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCT |
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FusionGenePPI for MKLN1_EXOC4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MKLN1 | RNPS1, MYC, RANBP9, ELAVL1, MKLN1, MAEA, GID8, RMND5A, SOX2, PTGER3, GDNF, GLIPR1L2, MMP7, SFRP2, TDGF1, GGH, MRPL4, GPS2, NR1H3, HLA-DPB1, ADCYAP1, PRG2, IFI30, UNK, DYNC1H1, BMP1, PRG3, INSL6, PIGT, CCDC120, TIGD5, SUCLA2, NFATC1, LILRB4, CARKD, IKZF1, C4orf27, TLE4, ARMC8, ZMYND19, GID4, HTRA2, WDR26, PMFBP1, AAMP, MMADHC, HSPBP1, LONP1, RSPH10B, NDUFS2, SOAT1, RMND5B, YPEL5, RANBP10, RAB8A, TRIM25 | EXOC4 | MYC, DLG3, EXOC3, GRIN2B, DLG4, EXOC7, GTF2E2, DISC1, DTNBP1, CEP63, EXOC1, MYO5A, EXOC2, EXOC8, EXOC5, IQCB1, EGFR, ATG5, ATG12, BECN1, SNAP29, BSG, TPM1, SETDB1, EXOC6, NTRK1, MED4, SCLT1, OFD1, PCM1, CNTROB, FGFR1OP, CEP128, CEP44, CNTRL, ODF2, DYNLT1, TMEM17, SNW1, CDC5L, PTAR1, MTMR4, STX11, IKBIP, IL1R2, GGA1, APLNR, EXOC3L2, EXOC6B, TSSC1, RABEP2, VPS51, RABEP1, RALB, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MKLN1_EXOC4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MKLN1_EXOC4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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