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Fusion gene ID: 21969 |
FusionGeneSummary for MINK1_USO1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MINK1_USO1 | Fusion gene ID: 21969 | Hgene | Tgene | Gene symbol | MINK1 | USO1 | Gene ID | 50488 | 8615 |
| Gene name | misshapen like kinase 1 | USO1 vesicle transport factor | |
| Synonyms | B55|MAP4K6|MINK|YSK2|ZC3 | P115|TAP|VDP | |
| Cytomap | 17p13.2 | 4q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | misshapen-like kinase 1GCK family kinase MINKMAPK/ERK kinase kinase kinase 6MEK kinase kinase 6MEKKK 6misshapen/NIK-related kinasemitogen-activated protein kinase kinase kinase kinase 6 | general vesicular transport factor p115USO1 vesicle docking protein homologtranscytosis associated proteinvesicle docking protein p115 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8N4C8 | O60763 | |
| Ensembl transtripts involved in fusion gene | ENST00000355280, ENST00000347992, ENST00000453408, | ENST00000538159, ENST00000514213, | |
| Fusion gene scores | * DoF score | 8 X 4 X 5=160 | 4 X 4 X 3=48 |
| # samples | 9 | 5 | |
| ** MAII score | log2(9/160*10)=-0.830074998557688 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: MINK1 [Title/Abstract] AND USO1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MINK1 | GO:0046777 | protein autophosphorylation | 15469942 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-38-4632-01A | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| TCGA | LD | LUAD | TCGA-38-4632-01A | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000355280 | ENST00000538159 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| In-frame | ENST00000355280 | ENST00000514213 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| In-frame | ENST00000347992 | ENST00000538159 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| In-frame | ENST00000347992 | ENST00000514213 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| In-frame | ENST00000453408 | ENST00000538159 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| In-frame | ENST00000453408 | ENST00000514213 | MINK1 | chr17 | 4736935 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000355280 | ENST00000538159 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000355280 | ENST00000514213 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000347992 | ENST00000538159 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000347992 | ENST00000514213 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000453408 | ENST00000538159 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
| intron-3CDS | ENST00000453408 | ENST00000514213 | MINK1 | chr17 | 4762623 | + | USO1 | chr4 | 76720775 | + |
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FusionProtFeatures for MINK1_USO1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MINK1 | USO1 |
| Serine/threonine kinase which acts as a negativeregulator of Ras-related Rap2-mediated signal transduction tocontrol neuronal structure and AMPA receptor trafficking. Requiredfor normal synaptic density, dendrite complexity, as well assurface AMPA receptor expression in hippocampal neurons. Canactivate the JNK and MAPK14/p38 pathways and mediates stimulationof the stress-activated protein kinase MAPK14/p38 MAPK downstreamof the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation byRAP2A, MBP and SMAD1. Has an essential function in negativeselection of thymocytes, perhaps by coupling NCK1 to activation ofJNK1. Isoform 4 can activate the JNK pathway. Involved in theregulation of actin cytoskeleton reorganization, cell-matrixadhesion, cell-cell adhesion and cell migration. | General vesicular transport factor required forintercisternal transport in the Golgi stack; it is required fortranscytotic fusion and/or subsequent binding of the vesicles tothe target membrane. May well act as a vesicular anchor byinteracting with the target membrane and holding the vesicular andtarget membranes in proximity. {ECO:0000250|UniProtKB:P41542}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000347992 | + | 1 | 32 | 359_495 | 19 | 1304 | Compositional bias | Note=Gln-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000347992 | + | 1 | 32 | 542_729 | 19 | 1304 | Compositional bias | Note=Pro-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000355280 | + | 1 | 32 | 359_495 | 19 | 1333 | Compositional bias | Note=Gln-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000355280 | + | 1 | 32 | 542_729 | 19 | 1333 | Compositional bias | Note=Pro-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000453408 | + | 1 | 32 | 359_495 | 19 | 1313 | Compositional bias | Note=Gln-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000453408 | + | 1 | 32 | 542_729 | 19 | 1313 | Compositional bias | Note=Pro-rich |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000347992 | + | 1 | 32 | 1019_1306 | 19 | 1304 | Domain | CNH |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000347992 | + | 1 | 32 | 25_289 | 19 | 1304 | Domain | Protein kinase |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000355280 | + | 1 | 32 | 1019_1306 | 19 | 1333 | Domain | CNH |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000355280 | + | 1 | 32 | 25_289 | 19 | 1333 | Domain | Protein kinase |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000453408 | + | 1 | 32 | 1019_1306 | 19 | 1313 | Domain | CNH |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000453408 | + | 1 | 32 | 25_289 | 19 | 1313 | Domain | Protein kinase |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000347992 | + | 1 | 32 | 31_39 | 19 | 1304 | Nucleotide binding | ATP |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000355280 | + | 1 | 32 | 31_39 | 19 | 1333 | Nucleotide binding | ATP |
| Hgene | >MINK1 | chr17:4736935 | chr4:76720775 | ENST00000453408 | + | 1 | 32 | 31_39 | 19 | 1313 | Nucleotide binding | ATP |
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FusionGeneSequence for MINK1_USO1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_498aa MGDPAPARSLDDIDLSALRGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNS LESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTL EQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRL REEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAF AKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLAD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1690nt GGCTGGCTCCGGGGAGATAGCGCCTGTCAGTCGGTGGGTCGGTCCTCGCGCCGGCCCTCCCCCTCCCCGGTCTCCGGGGGAGGCGCGGTG GAGTCCGCCCCCGGGGTTCTCCGATGGGGGAGAAGCGGCGACGGCGGCAGTGGAGTAACCGAGCCGGAGCGTGAGCGGCCCCGGTGCCCC GTTCCCCACGGAGGCCATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAAC AAGAGTTGGATTATTAATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCC ATTTCTTACAGGACAAATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTA TTTCAATGATAACTCACTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAA ACTAGGATTTATTAGCAAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGA TCATGAGTTTACGAAGCTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGA GGTGAAAAAAACATTAGAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAG GCAGCAGGTTTCTACATTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCA GTATAATCTTCTTAAAATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGA AGAAATTGGTAGATTGCGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGAT TGAAAATATGAAATCTTCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATT AAAACAGGAACTGGCAACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACA GAAAACAGAAGCGTTTGCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACT GTCAGCATTATTACAAGAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTC ATCTAATAGTACCATTGCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTT GGTGCTCTTGGCCGATCAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACT >In-frame_MINK1_ENST00000355280_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1690nt GGCTGGCTCCGGGGAGATAGCGCCTGTCAGTCGGTGGGTCGGTCCTCGCGCCGGCCCTCCCCCTCCCCGGTCTCCGGGGGAGGCGCGGTG GAGTCCGCCCCCGGGGTTCTCCGATGGGGGAGAAGCGGCGACGGCGGCAGTGGAGTAACCGAGCCGGAGCGTGAGCGGCCCCGGTGCCCC GTTCCCCACGGAGGCCATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAAC AAGAGTTGGATTATTAATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCC ATTTCTTACAGGACAAATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTA TTTCAATGATAACTCACTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAA ACTAGGATTTATTAGCAAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGA TCATGAGTTTACGAAGCTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGA GGTGAAAAAAACATTAGAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAG GCAGCAGGTTTCTACATTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCA GTATAATCTTCTTAAAATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGA AGAAATTGGTAGATTGCGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGAT TGAAAATATGAAATCTTCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATT AAAACAGGAACTGGCAACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACA GAAAACAGAAGCGTTTGCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACT GTCAGCATTATTACAAGAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTC ATCTAATAGTACCATTGCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTT GGTGCTCTTGGCCGATCAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACT >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1678nt GGAGATAGCGCCTGTCAGTCGGTGGGTCGGTCCTCGCGCCGGCCCTCCCCCTCCCCGGTCTCCGGGGGAGGCGCGGTGGAGTCCGCCCCC GGGGTTCTCCGATGGGGGAGAAGCGGCGACGGCGGCAGTGGAGTAACCGAGCCGGAGCGTGAGCGGCCCCGGTGCCCCGTTCCCCACGGA GGCCATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATT ATTAATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGG ACAAATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAA CTCACTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTAT TAGCAAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTAC GAAGCTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAAC ATTAGAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTC TACATTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCT TAAAATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAG ATTGCGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAA ATCTTCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACT GGCAACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGC GTTTGCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATT ACAAGAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTAC CATTGCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGC CGATCAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGA >In-frame_MINK1_ENST00000347992_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1678nt GGAGATAGCGCCTGTCAGTCGGTGGGTCGGTCCTCGCGCCGGCCCTCCCCCTCCCCGGTCTCCGGGGGAGGCGCGGTGGAGTCCGCCCCC GGGGTTCTCCGATGGGGGAGAAGCGGCGACGGCGGCAGTGGAGTAACCGAGCCGGAGCGTGAGCGGCCCCGGTGCCCCGTTCCCCACGGA GGCCATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATT ATTAATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGG ACAAATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAA CTCACTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTAT TAGCAAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTAC GAAGCTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAAC ATTAGAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTC TACATTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCT TAAAATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAG ATTGCGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAA ATCTTCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACT GGCAACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGC GTTTGCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATT ACAAGAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTAC CATTGCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGC CGATCAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGA >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000538159_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA >In-frame_MINK1_ENST00000453408_chr17_4736935_+_USO1_ENST00000514213_chr4_76720775_+_1494nt ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCCGCCCTGCGGGGAAGCAAAATACAAACAAGAGTTGGATTATTA ATGTTGCTTTGTACCTGGCTAAGCAATTGTCCCATTGCAGTAACGCATTTTCTTCACAATTCAGCCAATGTTCCATTTCTTACAGGACAA ATTGCAGAAAATCTTGGAGAAGAAGAGCAGTTGGTCCAAGGCTTATGTGCCCTTTTGTTGGGCATTTCGATTTATTTCAATGATAACTCA CTTGAGAGCTACATGAAAGAGAAGCTAAAACAACTGATTGAGAAGAGGATTGGCAAAGAGAATTTCATAGAGAAACTAGGATTTATTAGC AAACATGAGTTGTATTCCAGAGCATCTCAGAAACCCCAGCCAAACTTTCCCAGTCCAGAATACATGATATTTGATCATGAGTTTACGAAG CTGGTAAAAGAACTTGAAGGTGTTATAACTAAGGCTATTTATAAGTCCAGTGAAGAAGATAAAAAAGAAGAAGAGGTGAAAAAAACATTA GAACAGCATGACAATATTGTGACTCACTACAAAAATATGATTCGAGAGCAGGATCTCCAACTTGAGGAATTAAGGCAGCAGGTTTCTACA TTAAAATGTCAAAATGAACAGCTCCAGACGGCAGTCACACAGCAAGTATCACAGATCCAGCAGCACAAAGACCAGTATAATCTTCTTAAA ATACAGCTAGGAAAAGACAATCAGCATCAAGGTTCTTACAGTGAGGGGGCTCAGATGAATGGCATTCAGCCAGAAGAAATTGGTAGATTG CGAGAAGAGATAGAAGAATTAAAACGTAATCAGGAACTTTTACAAAGCCAGCTGACTGAAAAGGACTCTATGATTGAAAATATGAAATCT TCCCAAACATCTGGCACAAATGAACAGTCTTCAGCAATAGTTTCAGCTAGAGATTCTGAACAAGTTGCAGAATTAAAACAGGAACTGGCA ACTTTAAAGTCTCAGTTAAACTCACAATCTGTGGAGATCACCAAACTACAGACAGAAAAGCAGGAACTGTTACAGAAAACAGAAGCGTTT GCAAAATCAGTTGAGGTACAAGGAGAGACCGAGACTATAATAGCCACCAAAACTACTGATGTAGAAGGAAGACTGTCAGCATTATTACAA GAGACCAAAGAGTTAAAGAATGAAATTAAAGCTCTGTCTGAGGAAAGAACTGCCATTAAAGAGCAGCTGGATTCATCTAATAGTACCATT GCCATTTTACAAACTGAGAAAGACAAACTAGAGTTGGAAATTACAGATTCTAAAAAAGAACAAGATGATCTCTTGGTGCTCTTGGCCGAT CAAGATCAGAAAATACTGTCATTGAAGAATAAACTCAAGGATCTTGGTCATCCAGTTGAAGAAGAGGATGAACTTGAATCTGGAGACCAA |
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FusionGenePPI for MINK1_USO1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MINK1 | NCK1, NEDD4L, HSP90AA1, MAP4K4, TEX264, NCK2, NOP2, ATM, CDH1, PTPRK, NANOS2, PPP1R15A, TSEN15, TRIM25 | USO1 | GABPB1, C1orf94, GAK, PTP4A3, GOSR1, GOSR2, BET1, YKT6, STX5, SEC22A, SCFD1, GOLGA2, GOLGB1, RAB1A, CASP3, NCOA2, TRAF3, TP53, MAPK3, USO1, VCL, USP28, XIAP, ZNF593, PDE4DIP, SEC16A, PRKACA, CCDC168, TRIP11, PRKAR2B, CEP68, FAM184A, HUWE1, AKAP9, DUSP12, XPO7, PHYKPL, MDM2, RNF114, EFNB2, SETD9, TXNDC11, ACTL6A, SCN2B, CYP1A1, POLE3, CTTN, DNAJA1, HSP90B1, KHDRBS1, NTRK1, CEP290, TMEM17, CLTC, GTSE1, FOXQ1, CDC5L, CDH1, SLCO1B1, DDX20, ZNF488, SNRNP27, SEMA4F, CPNE5, FGB, TSNAXIP1, PDHA1, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MINK1_USO1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MINK1_USO1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | USO1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Tgene | USO1 | C0037274 | Dermatologic disorders | 1 | CTD_human |
| Tgene | USO1 | C0311375 | Arsenic Poisoning | 1 | CTD_human |
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