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Fusion gene ID: 21870 |
FusionGeneSummary for MIB1_SNRPD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MIB1_SNRPD1 | Fusion gene ID: 21870 | Hgene | Tgene | Gene symbol | MIB1 | SNRPD1 | Gene ID | 57534 | 6633 |
| Gene name | mindbomb E3 ubiquitin protein ligase 1 | small nuclear ribonucleoprotein D2 polypeptide | |
| Synonyms | DIP-1|DIP1|LVNC7|MIB|ZZANK2|ZZZ6 | SMD2|SNRPD1|Sm-D2 | |
| Cytomap | 18q11.2 | 19q13.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase MIB1DAPK-interacting protein 1RING-type E3 ubiquitin transferase MIB1ubiquitin ligase mind bombzinc finger ZZ type with ankyrin repeat domain protein 2 | small nuclear ribonucleoprotein Sm D2small nuclear ribonucleoprotein D2 polypeptide 16.5kDasnRNP core protein D2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q86YT6 | P62314 | |
| Ensembl transtripts involved in fusion gene | ENST00000578646, ENST00000261537, | ENST00000300413, ENST00000579618, ENST00000582475, | |
| Fusion gene scores | * DoF score | 8 X 8 X 7=448 | 4 X 3 X 4=48 |
| # samples | 10 | 4 | |
| ** MAII score | log2(10/448*10)=-2.16349873228288 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MIB1 [Title/Abstract] AND SNRPD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SNRPD1 | GO:0000387 | spliceosomal snRNP assembly | 18984161 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-44-4112-01A | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000578646 | ENST00000300413 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| 3UTR-3CDS | ENST00000578646 | ENST00000579618 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| 3UTR-intron | ENST00000578646 | ENST00000582475 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| In-frame | ENST00000261537 | ENST00000300413 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| In-frame | ENST00000261537 | ENST00000579618 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
| 5CDS-intron | ENST00000261537 | ENST00000582475 | MIB1 | chr18 | 19359646 | + | SNRPD1 | chr18 | 19202686 | + |
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FusionProtFeatures for MIB1_SNRPD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MIB1 | SNRPD1 |
| Core component of the spliceosomal U1, U2, U4 and U5small nuclear ribonucleoproteins (snRNPs), the building blocks ofthe spliceosome. Thereby, plays an important role in the splicingof cellular pre-mRNAs. Most spliceosomal snRNPs contain a commonset of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF andSNRPG that assemble in a heptameric protein ring on the Sm site ofthe small nuclear RNA to form the core snRNP. May act as a chargedprotein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts withRNA. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23333303}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MIB1_SNRPD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000300413_chr18_19202686_+_418aa MSNSRNNRVMVEGVGARVVRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDLRILDSAPTGIKHDGTMCDTCRQ QPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGARVVRGVDWQWEDQDGGNGRRGKVTE IQDWSASSPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGSFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGG WTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRG >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000579618_chr18_19202686_+_343aa MSNSRNNRVMVEGVGARVVRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDLRILDSAPTGIKHDGTMCDTCRQ QPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGARVVRGVDWQWEDQDGGNGRRGKVTE IQDWSASSPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGSFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000300413_chr18_19202686_+_1254nt ATGAGTAACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGAC GGCGGCGAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTAC CGCTGCTCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAG CAACCAATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTA AGACATCGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGA ATCTTTGCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAA ATCCAGGACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAG GGCATGTCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAAC AGGAATCCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGA TGGACTGATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGT GGCAATAGATTTTTGATGAAATTGAGTCATGAAACTGTAACCATTGAATTGAAGAACGGAACACAGGTCCATGGAACAATCACAGGTGTG GATGTCAGCATGAATACACATCTTAAAGCTGTGAAAATGACCCTGAAGAACAGAGAACCTGTACAGCTGGAAACGCTGAGTATTCGAGGA AATAACATTCGGTATTTTATTCTACCAGACAGTTTACCTCTGGATACACTACTTGTGGATGTTGAACCTAAGGTGAAATCTAAGAAAAGG >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000579618_chr18_19202686_+_1029nt ATGAGTAACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGAC GGCGGCGAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTAC CGCTGCTCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAG CAACCAATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTA AGACATCGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGA ATCTTTGCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAA ATCCAGGACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAG GGCATGTCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAAC AGGAATCCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGA TGGACTGATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGT GGCAATAGATTTTTGATGAAATTGAGTCATGAAACTGTAACCATTGAATTGAAGAACGGAACACAGGTCCATGGAACAATCACAGTTTAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000300413_chr18_19202686_+_2836nt TGCCCGCTCTCCGCCGCCGCCTCCGAGCAGCCGCGGGCCGCCCTCCACTCCGAGCGGGGGGCGCGGCGGCGACAGCTGGGCAGCGGCTTT GGGCTCCGCGGGGACCGCGCCGCCGCCCCCGTGAGTTATTCTCACGTCCCCCGGGGCTCGCTGCCGCCCCCGCCGACGCCTAGAGTCCGG CCCGGGCCCAACTCCCTCACGGGCCCCCCGGCGGCAGCGGCGGCGGCGGCGGCGGCAGCGGCGGAGCCCACCGCCCGGGCCCCGATGAGT AACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGACGGCGGC GAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTACCGCTGC TCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAGCAACCA ATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTAAGACAT CGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGAATCTTT GCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAAATCCAG GACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAGGGCATG TCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAACAGGAAT CCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGATGGACT GATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGTGGCAAT AGATTTTTGATGAAATTGAGTCATGAAACTGTAACCATTGAATTGAAGAACGGAACACAGGTCCATGGAACAATCACAGGTGTGGATGTC AGCATGAATACACATCTTAAAGCTGTGAAAATGACCCTGAAGAACAGAGAACCTGTACAGCTGGAAACGCTGAGTATTCGAGGAAATAAC ATTCGGTATTTTATTCTACCAGACAGTTTACCTCTGGATACACTACTTGTGGATGTTGAACCTAAGGTGAAATCTAAGAAAAGGGAAGCT GTTGCAGGAAGAGGCAGAGGAAGAGGAAGAGGAAGAGGACGTGGCCGTGGCAGAGGAAGAGGGGGTCCTAGGCGATAATGTCTCTCAAGA TTTCAAAGTCATATGAGATTTGGGATATTTTTTGTACAGGTTGTGTTTGTTTATGTCAGTTTTTAATAAACATAAATGTGGGACAGAGCT GTCTATTTAGTATATCAAAGTTTTAGTAGTTTCCTCCACATTCACGAAATTACCACAGTGAGAGCTAAGCATTTCTACTGGGCAGTTTCA TTTTTAGTTGATCAGGTTTTAAGTTTTTGAACTAAAATTTTTCTTTTTCTTTTTATGATGAATAAGGTTAAAATAAAAGCCTTAGACAAA TTAAATTTGGCAGAGTTTAATTGAGCAAAGGACAATTCACAAATCAGGTAGCCCCTGAACCATAATAGGCTCAGAGGCTTCAGCCCAGCT GCATAGTTGAAGATTTATGGACAGAAGGAAAGTGATGTATGGAAAATGGAAGTGAGATACAGCAACAGCCGGATTAGTTACAGTTCAGCG TTTGCCTTATTTGAATATGGTTTGAACAGTTCGCTGTCTTTGGTTGGCTGAAACTTAGTGATTGCCACAAGAGTAGGGTACCGTCTGTTT ACACGTCCAGTTAGGCTACAGTTCTATGTACTGAGAAACCTTTAAGCTGAACTTGAGATATGTAAAGAGACTTTAGGCTAAACTTAACAA TATATATAGGATATATACCCTTCTACTTCACATGCACTGAATATGCATTTTATTGCTTTACTCTTCATTCTGTGGCACCTACCCACAGGG GAAGTAAGAAGTTTGTTTTGGTATTTCGGAAACTAAAGTCCTTATGGGATGGGGTCTAGAATTGATTCTCCTTTCCTGAGTTTTACTCCA CGGAGTCTTAGGTACCTGGTAAAAAGTTGTCTTCTAAATTAAGGGTCATTGCTTTGTTGTCTAGCTGCTAATGTCTTACTTTTGTTTCTT TTGCTTTTTAATCAGTTCTTAATAGGATATAGTTTTATGTTTTCCAAGTTATAACTTGGAGTTAATGGTCACTAGATTATCAGTTATGAG CAGTGTTAAAATCTCCTATTAATGTGTAATGTACCTGTCAGTGCCTCCTTTATTAAGGGGTTCTTTGAGAATAAAAGAGAAAAGACCTAC TTTATTTGACAGCAAAACTGTTCTAATTGTTAATAAGGACTTTTAAAAATTGTTTTTGATTTGCTAAGCTCAGAAAAAATGTCTCTCAGT GCATCAGTTCTTTGTAAAGCTTACTACGAAGTATTTATATGCTAAGGAAAACAACTGAGGATGTGGGTGGCTTAAATCTGTATTTTCATC >In-frame_MIB1_ENST00000261537_chr18_19359646_+_SNRPD1_ENST00000579618_chr18_19202686_+_1362nt TGCCCGCTCTCCGCCGCCGCCTCCGAGCAGCCGCGGGCCGCCCTCCACTCCGAGCGGGGGGCGCGGCGGCGACAGCTGGGCAGCGGCTTT GGGCTCCGCGGGGACCGCGCCGCCGCCCCCGTGAGTTATTCTCACGTCCCCCGGGGCTCGCTGCCGCCCCCGCCGACGCCTAGAGTCCGG CCCGGGCCCAACTCCCTCACGGGCCCCCCGGCGGCAGCGGCGGCGGCGGCGGCGGCAGCGGCGGAGCCCACCGCCCGGGCCCCGATGAGT AACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGACGGCGGC GAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTACCGCTGC TCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAGCAACCA ATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTAAGACAT CGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGAATCTTT GCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAAATCCAG GACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAGGGCATG TCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAACAGGAAT CCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGATGGACT GATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGTGGCAAT AGATTTTTGATGAAATTGAGTCATGAAACTGTAACCATTGAATTGAAGAACGGAACACAGGTCCATGGAACAATCACAGTTTACCTCTGG ATACACTACTTGTGGATGTTGAACCTAAGGTGAAATCTAAGAAAAGGGAAGCTGTTGCAGGAAGAGGCAGAGGAAGAGGAAGAGGAAGAG |
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FusionGenePPI for MIB1_SNRPD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MIB1 | UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2N, UBE2U, UBE2W, UBC, JAG1, RYK, DLL1, AZI2, TBK1, PCM1, SNX5, DAPK1, CMIP, SMN1, CEP131, BLM, MIB1, USP9X, ZFC3H1, RANGAP1, ZBTB10, GEMIN4, MCM3, TOP3A, DDB1, TOP3B, RBBP4, MCM7, CDC27, CEP250, FSD1, PLK4, NTRK1, CENPJ, MED4, CEP290, CEP162, SSX2IP, CEP128, CNTRL, POC5, PCNT, PRKAR2B, OFD1, DYNLL1, PER3, CEP135, FGFR1OP, MAPRE1, CCDC14, PTPN22, TPTE2, LRRCC1, CHRNA3, FAM171B, ANKRD55, LPXN, EPN3, EPB41L4A, EPB41L5 | SNRPD1 | LSM8, RNU11, PRMT5, CLNS1A, WDR77, GEMIN5, SMN1, SNRPD2, SF3A2, DDX20, SMN2, CDC5L, SRRM2, RBM39, SREK1, HDGF, ARRB1, ARRB2, HNRNPA1, CUL3, CUL4A, CUL4B, CUL5, CUL2, CUL1, COPS5, COPS6, DCUN1D1, CAND1, NEDD8, SNRPB, SF3B3, SNRPE, SF3A1, SNRPA1, SNRPD3, PRPF8, SNRNP70, LSM2, SF3B1, SF3B2, YBX1, HNRNPU, SF3B5, SF3B6, HNRNPK, PRPF6, SNRNP200, HNRNPM, EFTUD2, U2AF2, HNRNPA2B1, PRPF19, TPR, SART1, DDX5, BCAS2, TOP1, EEF1A1, HSPA5, UCHL3, TRIM28, RPS7, SRP14, SUPT16H, HSP90AB1, PTGES3, APEX1, ESR1, MAGOH, EIF4A3, SMURF1, CTNNB1, FN1, VCAM1, U2AF1, LSM3, IFIT1, IFIT2, IFIT3, IL7R, ITGA4, PAN2, CD81, IGSF8, ICAM1, NPM1, EGFR, SRPK2, SRPK3, PRPF4B, FERMT2, PDHB, SCLY, EIF5, WWOX, ASB1, ASB2, OBSL1, EZH2, SUZ12, EED, RNF2, BLK, DDX23, SNRNP40, SNUPN, MCFD2, PRPF31, RCC2, RUVBL1, SF3A3, DHX9, DPY30, LSM7, LUC7L, LUC7L2, PDCD4, SNRPF, TIA1, TMOD3, USP7, YWHAE, YWHAQ, RNU12, GEMIN7, CRBN, PTPN4, SNRPN, SNRPG, CD2BP2, LSM6, GEMIN2, PRPF3, NCL, CYLD, AAR2, EAPP, TSSC4, HEY1, LMNA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MIB1_SNRPD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MIB1_SNRPD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MIB1 | C0036572 | Seizures | 1 | CTD_human |
| Hgene | MIB1 | C3554496 | LEFT VENTRICULAR NONCOMPACTION 7 | 1 | UNIPROT |
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