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Fusion gene ID: 21869 |
FusionGeneSummary for MIB1_MYO5B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MIB1_MYO5B | Fusion gene ID: 21869 | Hgene | Tgene | Gene symbol | MIB1 | MYO5B | Gene ID | 57534 | 4645 |
| Gene name | mindbomb E3 ubiquitin protein ligase 1 | myosin VB | |
| Synonyms | DIP-1|DIP1|LVNC7|MIB|ZZANK2|ZZZ6 | - | |
| Cytomap | 18q11.2 | 18q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase MIB1DAPK-interacting protein 1RING-type E3 ubiquitin transferase MIB1ubiquitin ligase mind bombzinc finger ZZ type with ankyrin repeat domain protein 2 | unconventional myosin-VbMYO5B variant proteinmyosin-Vb | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q86YT6 | Q9ULV0 | |
| Ensembl transtripts involved in fusion gene | ENST00000578646, ENST00000261537, | ENST00000285039, ENST00000324581, ENST00000592688, ENST00000587895, | |
| Fusion gene scores | * DoF score | 8 X 8 X 7=448 | 9 X 9 X 7=567 |
| # samples | 10 | 11 | |
| ** MAII score | log2(10/448*10)=-2.16349873228288 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/567*10)=-2.36584521141757 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MIB1 [Title/Abstract] AND MYO5B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-G4-6322-01A | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000578646 | ENST00000285039 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| 3UTR-3CDS | ENST00000578646 | ENST00000324581 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| 3UTR-intron | ENST00000578646 | ENST00000592688 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| 3UTR-intron | ENST00000578646 | ENST00000587895 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| In-frame | ENST00000261537 | ENST00000285039 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| In-frame | ENST00000261537 | ENST00000324581 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| 5CDS-intron | ENST00000261537 | ENST00000592688 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
| 5CDS-intron | ENST00000261537 | ENST00000587895 | MIB1 | chr18 | 19438607 | + | MYO5B | chr18 | 47406825 | - |
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FusionProtFeatures for MIB1_MYO5B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MIB1 | MYO5B |
| May be involved in vesicular trafficking via itsassociation with the CART complex. The CART complex is necessaryfor efficient transferrin receptor recycling but not for EGFRdegradation. Required in a complex with RAB11A and RAB11FIP2 forthe transport of NPC1L1 to the plasma membrane. Together withRAB11A participates in CFTR trafficking to the plasma membrane andTF (transferrin) recycling in nonpolarized cells. Together withRAB11A and RAB8A participates in epithelial cell polarization.Together with RAB25 regulates transcytosis.{ECO:0000269|PubMed:21206382, ECO:0000269|PubMed:21282656}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MIB1_MYO5B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000285039_chr18_47406825_-_1794aa MSNSRNNRVMVEGVGARVVRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDLRILDSAPTGIKHDGTMCDTCRQ QPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGARVVRGVDWQWEDQDGGNGRRGKVTE IQDWSASSPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGSFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGG WTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAE AMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVASAGSAISNASGERLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDL LKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNK GHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD MQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKCHKEKVSGQVGSRSPSMIS NDSETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQC RAVVERRVPFIMCCGGKSSEDATDDISSGNIPVLQKDKDNTNVNADVQKLQQQLQDIKEQRVADLEQENALLKDEKEQLNNQILCQSKDE FAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIG LEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVAD QATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS KTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNE NLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSG TVPCLPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNF DLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDP EIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCT >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000324581_chr18_47406825_-_1768aa MSNSRNNRVMVEGVGARVVRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDLRILDSAPTGIKHDGTMCDTCRQ QPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGARVVRGVDWQWEDQDGGNGRRGKVTE IQDWSASSPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGSFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGG WTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAE AMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVASAGSAISNASGERLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDL LKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNK GHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD MQDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLCPDPNLCKALAKCHKEKVSGQVGSRSPSMIS NDSETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQC RAVVERRVPFIMCCGGKSSEDATDDISSGNIPVLQKDKDNTNVNADVQKLQQQLQDIKEQRVADLEQENALLKDEKEQLNNQILCQSKDE FAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIG LEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVAD QATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNR LLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYM KKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVPCLPAYILYMCIRHADYTNDDLKV HSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEG VLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRK DVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000285039_chr18_47406825_-_5382nt ATGAGTAACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGAC GGCGGCGAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTAC CGCTGCTCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAG CAACCAATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTA AGACATCGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGA ATCTTTGCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAA ATCCAGGACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAG GGCATGTCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAAC AGGAATCCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGA TGGACTGATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGT GGCAATAGGTGGACCTTCAATCCTGCTGTTCTCACTAAAGCGAACATTGTCCGAAGTGGAGATGCTGCTCAGGGTGCAGAAGGAGGCACC TCGCAGTTTCAAGTGGGTGATCTTGTACAAGTTTGTTATGACCTGGAACGAATTAAACTTCTACAAAGAGGACATGGAGAATGGGCTGAA GCGATGCTTCCAACTTTAGGTAAAGTTGGCCGAGTACAACAGATTTATTCAGACAGTGATTTAAAGGTGGAAGTTTGTGGAACATCTTGG ACATACAATCCAGCAGCAGTTTCCAAGGTGGCATCTGCAGGATCAGCCATTAGCAATGCATCTGGTGAAAGACTCTCACAACTCCTGAAG AAATTATTTGAAACCCAAGAATCTGGTGACCTCAATGAAGAATTAGTTAAGGCTGCTGCCAATGGAGATGTTGCTAAAGTGGAAGATTTG CTTAAAAGACCAGATGTGGATGTAAATGGGCAATGTGCTGGCCACACAGCTATGCAAGCTGCTAGTCAGAATGGACATGTTGACATTTTG AAGTTACTTTTGAAGCAAAACGTGGATGTCGAAGCAGAGGATAAAGATGGTGATAGAGCAGTTCACCATGCAGCTTTTGGAGATGAAGGC GCTGTTATAGAAGTACTACATCGAGGTAGTGCTGATTTGAATGCTCGAAACAAGCGCCGACAGACACCACTTCATATTGCTGTCAATAAA GGTCATCTTCAAGTTGTGAAGACTTTATTGGACTTTGGCTGTCATCCCAGTCTCCAGGATTCTGAAGGTGATACCCCTCTTCATGATGCA ATAAGTAAGAAACGTGATGATATCCTAGCAGTTCTTTTGGAAGCTGGAGCAGATGTTACCATCACAAACAATAATGGATTTAATGCTCTG CATCATGCTGCACTAAGGGGAAATCCCAGTGCAATGCGTGTTTTACTATCTAAATTACCAAGACCATGGATTGTGGATGAGAAGAAAGAT GATGGTTATACTGCCTTACATCTGGCTGCCCTTAATAATCACGTAGAAGTGGCTGAACTGTTGGTACATCAGGGTAATGCAAACCTGGAT ATCCAGAATGTGAACCAACAAACTGCCCTACACCTTGCTGTTGAACGACAGCATACCCAGATTGTTAGGCTTTTGGTCCGTGCAGGTGCC AAGCTTGATATTCAGGATAAGGATGGGGATACTCCTTTGCATGAAGCTCTAAGGCATCACACTTTGTCTCAGCTACGTCAGCTCCAAGAT ATGCAAGATGTGGGGAAGGTGGATGCTGCCTGGGAGCCATCCAAAAACACGTTAATAATGGGACTTGGTACCCAGGGGGCAGAGAAGAAG AGTGCAGCATCTATTGCCTGTTTCTTGGCAGCCAATGGTGCTGACCTGAGCATTCGAAATAAGAAGGGTCAATCGCCACTTGATCTCTGT CCTGATCCGAATCTCTGCAAAGCACTGGCAAAGTGTCATAAGGAAAAAGTCAGTGGTCAAGTGGGTTCTCGGAGTCCTTCTATGATTAGT AATGATTCTGAAACCTTAGAAGAGTGTATGGTGTGCTCAGATATGAAGAGAGATACTCTTTTTGGTCCATGTGGACATATTGCTACCTGT TCTTTATGTTCTCCACGTGTCAAGAAATGCCTCATCTGTAAAGAACAGGTTCAATCCAGGACAAAGATTGAAGAATGTGTGGTATGCTCT GACAAGAAAGCAGCTGTTCTTTTTCAACCCTGTGGCCACATGTGTGCTTGTGAGAACTGTGCTAACCTGATGAAAAAGTGTGTGCAGTGT CGAGCAGTAGTTGAACGAAGAGTGCCTTTCATTATGTGCTGTGGAGGGAAAAGTTCAGAAGATGCCACTGATGATATCTCAAGTGGGAAT ATTCCAGTATTACAAAAGGACAAGGATAATACCAATGTCAATGCAGATGTGCAAAAGTTGCAGCAACAGTTACAAGACATTAAAGAGCAG CGAGTTGCAGACCTGGAGCAAGAAAATGCTCTCTTGAAAGATGAGAAAGAACAGCTCAACAACCAAATCCTGTGCCAGTCTAAAGATGAA TTTGCCCAGAACTCTGTGAAGGAAAATCTCATGAAGAAAGAACTGGAGGAGGAGCGATCCCGGTACCAGAACCTTGTGAAGGAATATTCA CAGTTGGAGCAGAGATACGACAACCTTCGGGATGAAATGACCATCATAAAGCAAACTCCAGGTCATAGGCGGAACCCATCAAACCAAAGT AGCTTAGAATCTGACTCCAATTACCCCTCCATCTCCACATCTGAGATCGGAGACACTGAGGATGCCCTCCAGCAGGTGGAGGAAATTGGC CTGGAGAAGGCAGCCATGGACATGACGGTCTTCCTGAAGCTGCAGAAGAGAGTACGGGAGCTGGAGCAGGAGAGGAAAAAGCTGCAAGTG CAGCTGGAGAAGAGAGAACAGCAGGACAGCAAGAAAGTCCAGGCGGAACCACCACAGACTGACATAGATTTGGACCCGAATGCAGATCTG GCCTACAATAGTCTGAAGAGGCAAGAGCTGGAGTCAGAGAACAAAAAGCTGAAGAATGACCTGAATGAGCTGAGGAAAGCCGTGGCCGAC CAAGCCACGCAGAATAACTCCAGCCACGGCTCCCCAGATAGCTACAGCCTCCTGCTGAACCAGCTCAAGCTGGCCCACGAGGAGCTCGAG GTGCGCAAGGAGGAGGTGCTCATCCTCAGGACCCAGATCGTGAGCGCCGACCAGCGGCGACTCGCCGGCAGGAACGCGGAGCCGAACATT AATGCCAGATCAAGTTGGCCTAACAGTGAAAAGCATGTTGACCAGGAGGATGCCATTGAGGCCTATCACGGGGTCTGCCAGACAAACAGC AAGACTGAGGATTGGGGATATTTAAATGAAGATGGAGAACTCGGCTTGGCCTACCAAGGCCTAAAGCAAGTTGCCAGGCTGCTGGAGGCT CAGCTGCAGGCCCAGAGCCTGGAGCATGAGGAGGAGGTGGAGCATCTCAAGGCTCAGCTCGAGGCCCTGAAGGAGGAGATGGACAAACAG CAGCAGACCTTCTGCCAGACGCTACTGCTCTCCCCAGAGGCCCAGGTGGAATTCGGCGTTCAGCAGGAAATATCCCGGCTGACCAACGAG AATCTGGACCTTAAAGAACTGGTAGAAAAGCTGGAAAAGAATGAGAGGAAGCTCAAAAAGCAACTGAAGATTTACATGAAGAAAGCCCAG GACCTAGAAGCTGCCCAGGCATTGGCCCAGAGTGAGAGGAAGCGCCATGAGCTCAACAGGCAGGTCACGGTCCAGCGGAAAGAGAAGGAT TTCCAGGGCATGCTGGAGTACCACAAAGAGGACGAGGCCCTCCTCATCCGGAACCTGGTGACAGACTTGAAGCCCCAGATGCTGTCGGGC ACAGTGCCCTGTCTCCCCGCCTACATCCTCTACATGTGCATCCGGCACGCGGACTACACCAACGACGATCTCAAGGTGCACTCCCTGCTG ACCTCCACCATCAACGGCATTAAGAAAGTCCTGAAAAAGCACAATGATGACTTTGAGATGACGTCATTCTGGTTATCCAACACCTGCCGC CTTCTTCACTGTCTGAAGCAGTACAGCGGGGATGAGGGCTTCATGACTCAGAACACTGCAAAGCAGAATGAACACTGTCTTAAGAATTTT GACCTCACCGAATACCGTCAGGTGCTGAGTGACCTTTCCATTCAGATCTACCAGCAGCTCATTAAAATTGCCGAGGGCGTGTTACAGCCG ATGATAGTTTCTGCCATGTTGGAAAATGAGAGCATTCAGGGTCTATCTGGTGTGAAGCCCACCGGCTACCGGAAGCGCTCCTCCAGCATG GCAGATGGGGATAACTCATACTGCCTGGAAGCTATCATCCGCCAGATGAATGCCTTTCATACAGTCATGTGTGACCAGGGCTTGGACCCT GAGATCATCCTGCAGGTATTCAAACAGCTCTTCTACATGATCAACGCAGTGACTCTTAACAACCTGCTCTTGCGGAAGGACGTCTGCTCT TGGAGCACAGGCATGCAACTCAGGTACAATATAAGTCAGCTTGAGGAGTGGCTTCGGGGAAGAAACCTTCACCAGAGTGGAGCAGTTCAG ACCATGGAACCTCTGATCCAAGCAGCCCAGCTCCTGCAATTAAAGAAGAAAACCCAGGAGGACGCAGAGGCTATCTGCTCCCTGTGTACC TCCCTCAGCACCCAGCAGATTGTCAAAATTTTAAACCTTTATACTCCCCTGAATGAATTTGAAGAACGGGTAACAGTGGCCTTTATACGA ACAATCCAGGCACAACTACAAGAGCGGAATGACCCTCAGCAACTGCTATTAGATGCCAAGCACATGTTTCCTGTTTTGTTTCCATTTAAT >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000324581_chr18_47406825_-_5304nt ATGAGTAACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGAC GGCGGCGAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTAC CGCTGCTCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAG CAACCAATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTA AGACATCGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGA ATCTTTGCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAA ATCCAGGACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAG GGCATGTCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAAC AGGAATCCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGA TGGACTGATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGT GGCAATAGGTGGACCTTCAATCCTGCTGTTCTCACTAAAGCGAACATTGTCCGAAGTGGAGATGCTGCTCAGGGTGCAGAAGGAGGCACC TCGCAGTTTCAAGTGGGTGATCTTGTACAAGTTTGTTATGACCTGGAACGAATTAAACTTCTACAAAGAGGACATGGAGAATGGGCTGAA GCGATGCTTCCAACTTTAGGTAAAGTTGGCCGAGTACAACAGATTTATTCAGACAGTGATTTAAAGGTGGAAGTTTGTGGAACATCTTGG ACATACAATCCAGCAGCAGTTTCCAAGGTGGCATCTGCAGGATCAGCCATTAGCAATGCATCTGGTGAAAGACTCTCACAACTCCTGAAG AAATTATTTGAAACCCAAGAATCTGGTGACCTCAATGAAGAATTAGTTAAGGCTGCTGCCAATGGAGATGTTGCTAAAGTGGAAGATTTG CTTAAAAGACCAGATGTGGATGTAAATGGGCAATGTGCTGGCCACACAGCTATGCAAGCTGCTAGTCAGAATGGACATGTTGACATTTTG AAGTTACTTTTGAAGCAAAACGTGGATGTCGAAGCAGAGGATAAAGATGGTGATAGAGCAGTTCACCATGCAGCTTTTGGAGATGAAGGC GCTGTTATAGAAGTACTACATCGAGGTAGTGCTGATTTGAATGCTCGAAACAAGCGCCGACAGACACCACTTCATATTGCTGTCAATAAA GGTCATCTTCAAGTTGTGAAGACTTTATTGGACTTTGGCTGTCATCCCAGTCTCCAGGATTCTGAAGGTGATACCCCTCTTCATGATGCA ATAAGTAAGAAACGTGATGATATCCTAGCAGTTCTTTTGGAAGCTGGAGCAGATGTTACCATCACAAACAATAATGGATTTAATGCTCTG CATCATGCTGCACTAAGGGGAAATCCCAGTGCAATGCGTGTTTTACTATCTAAATTACCAAGACCATGGATTGTGGATGAGAAGAAAGAT GATGGTTATACTGCCTTACATCTGGCTGCCCTTAATAATCACGTAGAAGTGGCTGAACTGTTGGTACATCAGGGTAATGCAAACCTGGAT ATCCAGAATGTGAACCAACAAACTGCCCTACACCTTGCTGTTGAACGACAGCATACCCAGATTGTTAGGCTTTTGGTCCGTGCAGGTGCC AAGCTTGATATTCAGGATAAGGATGGGGATACTCCTTTGCATGAAGCTCTAAGGCATCACACTTTGTCTCAGCTACGTCAGCTCCAAGAT ATGCAAGATGTGGGGAAGGTGGATGCTGCCTGGGAGCCATCCAAAAACACGTTAATAATGGGACTTGGTACCCAGGGGGCAGAGAAGAAG AGTGCAGCATCTATTGCCTGTTTCTTGGCAGCCAATGGTGCTGACCTGAGCATTCGAAATAAGAAGGGTCAATCGCCACTTGATCTCTGT CCTGATCCGAATCTCTGCAAAGCACTGGCAAAGTGTCATAAGGAAAAAGTCAGTGGTCAAGTGGGTTCTCGGAGTCCTTCTATGATTAGT AATGATTCTGAAACCTTAGAAGAGTGTATGGTGTGCTCAGATATGAAGAGAGATACTCTTTTTGGTCCATGTGGACATATTGCTACCTGT TCTTTATGTTCTCCACGTGTCAAGAAATGCCTCATCTGTAAAGAACAGGTTCAATCCAGGACAAAGATTGAAGAATGTGTGGTATGCTCT GACAAGAAAGCAGCTGTTCTTTTTCAACCCTGTGGCCACATGTGTGCTTGTGAGAACTGTGCTAACCTGATGAAAAAGTGTGTGCAGTGT CGAGCAGTAGTTGAACGAAGAGTGCCTTTCATTATGTGCTGTGGAGGGAAAAGTTCAGAAGATGCCACTGATGATATCTCAAGTGGGAAT ATTCCAGTATTACAAAAGGACAAGGATAATACCAATGTCAATGCAGATGTGCAAAAGTTGCAGCAACAGTTACAAGACATTAAAGAGCAG CGAGTTGCAGACCTGGAGCAAGAAAATGCTCTCTTGAAAGATGAGAAAGAACAGCTCAACAACCAAATCCTGTGCCAGTCTAAAGATGAA TTTGCCCAGAACTCTGTGAAGGAAAATCTCATGAAGAAAGAACTGGAGGAGGAGCGATCCCGGTACCAGAACCTTGTGAAGGAATATTCA CAGTTGGAGCAGAGATACGACAACCTTCGGGATGAAATGACCATCATAAAGCAAACTCCAGGTCATAGGCGGAACCCATCAAACCAAAGT AGCTTAGAATCTGACTCCAATTACCCCTCCATCTCCACATCTGAGATCGGAGACACTGAGGATGCCCTCCAGCAGGTGGAGGAAATTGGC CTGGAGAAGGCAGCCATGGACATGACGGTCTTCCTGAAGCTGCAGAAGAGAGTACGGGAGCTGGAGCAGGAGAGGAAAAAGCTGCAAGTG CAGCTGGAGAAGAGAGAACAGCAGGACAGCAAGAAAGTCCAGGCGGAACCACCACAGACTGACATAGATTTGGACCCGAATGCAGATCTG GCCTACAATAGTCTGAAGAGGCAAGAGCTGGAGTCAGAGAACAAAAAGCTGAAGAATGACCTGAATGAGCTGAGGAAAGCCGTGGCCGAC CAAGCCACGCAGAATAACTCCAGCCACGGCTCCCCAGATAGCTACAGCCTCCTGCTGAACCAGCTCAAGCTGGCCCACGAGGAGCTCGAG GTGCGCAAGGAGGAGGTGCTCATCCTCAGGACCCAGATCGTGAGCGCCGACCAGCGGCGACTCGCCGGCAGGAACGCGGAGCCGAACATT AATGCCAGATCAAGTTGGCCTAACAGTGAAAAGCATGTTGACCAGGAGGATGCCATTGAGGCCTATCACGGGGTCTGCCAGACAAACAGG CTGCTGGAGGCTCAGCTGCAGGCCCAGAGCCTGGAGCATGAGGAGGAGGTGGAGCATCTCAAGGCTCAGCTCGAGGCCCTGAAGGAGGAG ATGGACAAACAGCAGCAGACCTTCTGCCAGACGCTACTGCTCTCCCCAGAGGCCCAGGTGGAATTCGGCGTTCAGCAGGAAATATCCCGG CTGACCAACGAGAATCTGGACCTTAAAGAACTGGTAGAAAAGCTGGAAAAGAATGAGAGGAAGCTCAAAAAGCAACTGAAGATTTACATG AAGAAAGCCCAGGACCTAGAAGCTGCCCAGGCATTGGCCCAGAGTGAGAGGAAGCGCCATGAGCTCAACAGGCAGGTCACGGTCCAGCGG AAAGAGAAGGATTTCCAGGGCATGCTGGAGTACCACAAAGAGGACGAGGCCCTCCTCATCCGGAACCTGGTGACAGACTTGAAGCCCCAG ATGCTGTCGGGCACAGTGCCCTGTCTCCCCGCCTACATCCTCTACATGTGCATCCGGCACGCGGACTACACCAACGACGATCTCAAGGTG CACTCCCTGCTGACCTCCACCATCAACGGCATTAAGAAAGTCCTGAAAAAGCACAATGATGACTTTGAGATGACGTCATTCTGGTTATCC AACACCTGCCGCCTTCTTCACTGTCTGAAGCAGTACAGCGGGGATGAGGGCTTCATGACTCAGAACACTGCAAAGCAGAATGAACACTGT CTTAAGAATTTTGACCTCACCGAATACCGTCAGGTGCTGAGTGACCTTTCCATTCAGATCTACCAGCAGCTCATTAAAATTGCCGAGGGC GTGTTACAGCCGATGATAGTTTCTGCCATGTTGGAAAATGAGAGCATTCAGGGTCTATCTGGTGTGAAGCCCACCGGCTACCGGAAGCGC TCCTCCAGCATGGCAGATGGGGATAACTCATACTGCCTGGAAGCTATCATCCGCCAGATGAATGCCTTTCATACAGTCATGTGTGACCAG GGCTTGGACCCTGAGATCATCCTGCAGGTATTCAAACAGCTCTTCTACATGATCAACGCAGTGACTCTTAACAACCTGCTCTTGCGGAAG GACGTCTGCTCTTGGAGCACAGGCATGCAACTCAGGTACAATATAAGTCAGCTTGAGGAGTGGCTTCGGGGAAGAAACCTTCACCAGAGT GGAGCAGTTCAGACCATGGAACCTCTGATCCAAGCAGCCCAGCTCCTGCAATTAAAGAAGAAAACCCAGGAGGACGCAGAGGCTATCTGC TCCCTGTGTACCTCCCTCAGCACCCAGCAGATTGTCAAAATTTTAAACCTTTATACTCCCCTGAATGAATTTGAAGAACGGGTAACAGTG GCCTTTATACGAACAATCCAGGCACAACTACAAGAGCGGAATGACCCTCAGCAACTGCTATTAGATGCCAAGCACATGTTTCCTGTTTTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000285039_chr18_47406825_-_9304nt TGCCCGCTCTCCGCCGCCGCCTCCGAGCAGCCGCGGGCCGCCCTCCACTCCGAGCGGGGGGCGCGGCGGCGACAGCTGGGCAGCGGCTTT GGGCTCCGCGGGGACCGCGCCGCCGCCCCCGTGAGTTATTCTCACGTCCCCCGGGGCTCGCTGCCGCCCCCGCCGACGCCTAGAGTCCGG CCCGGGCCCAACTCCCTCACGGGCCCCCCGGCGGCAGCGGCGGCGGCGGCGGCGGCAGCGGCGGAGCCCACCGCCCGGGCCCCGATGAGT AACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGACGGCGGC GAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTACCGCTGC TCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAGCAACCA ATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTAAGACAT CGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGAATCTTT GCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAAATCCAG GACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAGGGCATG TCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAACAGGAAT CCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGATGGACT GATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGTGGCAAT AGGTGGACCTTCAATCCTGCTGTTCTCACTAAAGCGAACATTGTCCGAAGTGGAGATGCTGCTCAGGGTGCAGAAGGAGGCACCTCGCAG TTTCAAGTGGGTGATCTTGTACAAGTTTGTTATGACCTGGAACGAATTAAACTTCTACAAAGAGGACATGGAGAATGGGCTGAAGCGATG CTTCCAACTTTAGGTAAAGTTGGCCGAGTACAACAGATTTATTCAGACAGTGATTTAAAGGTGGAAGTTTGTGGAACATCTTGGACATAC AATCCAGCAGCAGTTTCCAAGGTGGCATCTGCAGGATCAGCCATTAGCAATGCATCTGGTGAAAGACTCTCACAACTCCTGAAGAAATTA TTTGAAACCCAAGAATCTGGTGACCTCAATGAAGAATTAGTTAAGGCTGCTGCCAATGGAGATGTTGCTAAAGTGGAAGATTTGCTTAAA AGACCAGATGTGGATGTAAATGGGCAATGTGCTGGCCACACAGCTATGCAAGCTGCTAGTCAGAATGGACATGTTGACATTTTGAAGTTA CTTTTGAAGCAAAACGTGGATGTCGAAGCAGAGGATAAAGATGGTGATAGAGCAGTTCACCATGCAGCTTTTGGAGATGAAGGCGCTGTT ATAGAAGTACTACATCGAGGTAGTGCTGATTTGAATGCTCGAAACAAGCGCCGACAGACACCACTTCATATTGCTGTCAATAAAGGTCAT CTTCAAGTTGTGAAGACTTTATTGGACTTTGGCTGTCATCCCAGTCTCCAGGATTCTGAAGGTGATACCCCTCTTCATGATGCAATAAGT AAGAAACGTGATGATATCCTAGCAGTTCTTTTGGAAGCTGGAGCAGATGTTACCATCACAAACAATAATGGATTTAATGCTCTGCATCAT GCTGCACTAAGGGGAAATCCCAGTGCAATGCGTGTTTTACTATCTAAATTACCAAGACCATGGATTGTGGATGAGAAGAAAGATGATGGT TATACTGCCTTACATCTGGCTGCCCTTAATAATCACGTAGAAGTGGCTGAACTGTTGGTACATCAGGGTAATGCAAACCTGGATATCCAG AATGTGAACCAACAAACTGCCCTACACCTTGCTGTTGAACGACAGCATACCCAGATTGTTAGGCTTTTGGTCCGTGCAGGTGCCAAGCTT GATATTCAGGATAAGGATGGGGATACTCCTTTGCATGAAGCTCTAAGGCATCACACTTTGTCTCAGCTACGTCAGCTCCAAGATATGCAA GATGTGGGGAAGGTGGATGCTGCCTGGGAGCCATCCAAAAACACGTTAATAATGGGACTTGGTACCCAGGGGGCAGAGAAGAAGAGTGCA GCATCTATTGCCTGTTTCTTGGCAGCCAATGGTGCTGACCTGAGCATTCGAAATAAGAAGGGTCAATCGCCACTTGATCTCTGTCCTGAT CCGAATCTCTGCAAAGCACTGGCAAAGTGTCATAAGGAAAAAGTCAGTGGTCAAGTGGGTTCTCGGAGTCCTTCTATGATTAGTAATGAT TCTGAAACCTTAGAAGAGTGTATGGTGTGCTCAGATATGAAGAGAGATACTCTTTTTGGTCCATGTGGACATATTGCTACCTGTTCTTTA TGTTCTCCACGTGTCAAGAAATGCCTCATCTGTAAAGAACAGGTTCAATCCAGGACAAAGATTGAAGAATGTGTGGTATGCTCTGACAAG AAAGCAGCTGTTCTTTTTCAACCCTGTGGCCACATGTGTGCTTGTGAGAACTGTGCTAACCTGATGAAAAAGTGTGTGCAGTGTCGAGCA GTAGTTGAACGAAGAGTGCCTTTCATTATGTGCTGTGGAGGGAAAAGTTCAGAAGATGCCACTGATGATATCTCAAGTGGGAATATTCCA GTATTACAAAAGGACAAGGATAATACCAATGTCAATGCAGATGTGCAAAAGTTGCAGCAACAGTTACAAGACATTAAAGAGCAGCGAGTT GCAGACCTGGAGCAAGAAAATGCTCTCTTGAAAGATGAGAAAGAACAGCTCAACAACCAAATCCTGTGCCAGTCTAAAGATGAATTTGCC CAGAACTCTGTGAAGGAAAATCTCATGAAGAAAGAACTGGAGGAGGAGCGATCCCGGTACCAGAACCTTGTGAAGGAATATTCACAGTTG GAGCAGAGATACGACAACCTTCGGGATGAAATGACCATCATAAAGCAAACTCCAGGTCATAGGCGGAACCCATCAAACCAAAGTAGCTTA GAATCTGACTCCAATTACCCCTCCATCTCCACATCTGAGATCGGAGACACTGAGGATGCCCTCCAGCAGGTGGAGGAAATTGGCCTGGAG AAGGCAGCCATGGACATGACGGTCTTCCTGAAGCTGCAGAAGAGAGTACGGGAGCTGGAGCAGGAGAGGAAAAAGCTGCAAGTGCAGCTG GAGAAGAGAGAACAGCAGGACAGCAAGAAAGTCCAGGCGGAACCACCACAGACTGACATAGATTTGGACCCGAATGCAGATCTGGCCTAC AATAGTCTGAAGAGGCAAGAGCTGGAGTCAGAGAACAAAAAGCTGAAGAATGACCTGAATGAGCTGAGGAAAGCCGTGGCCGACCAAGCC ACGCAGAATAACTCCAGCCACGGCTCCCCAGATAGCTACAGCCTCCTGCTGAACCAGCTCAAGCTGGCCCACGAGGAGCTCGAGGTGCGC AAGGAGGAGGTGCTCATCCTCAGGACCCAGATCGTGAGCGCCGACCAGCGGCGACTCGCCGGCAGGAACGCGGAGCCGAACATTAATGCC AGATCAAGTTGGCCTAACAGTGAAAAGCATGTTGACCAGGAGGATGCCATTGAGGCCTATCACGGGGTCTGCCAGACAAACAGCAAGACT GAGGATTGGGGATATTTAAATGAAGATGGAGAACTCGGCTTGGCCTACCAAGGCCTAAAGCAAGTTGCCAGGCTGCTGGAGGCTCAGCTG CAGGCCCAGAGCCTGGAGCATGAGGAGGAGGTGGAGCATCTCAAGGCTCAGCTCGAGGCCCTGAAGGAGGAGATGGACAAACAGCAGCAG ACCTTCTGCCAGACGCTACTGCTCTCCCCAGAGGCCCAGGTGGAATTCGGCGTTCAGCAGGAAATATCCCGGCTGACCAACGAGAATCTG GACCTTAAAGAACTGGTAGAAAAGCTGGAAAAGAATGAGAGGAAGCTCAAAAAGCAACTGAAGATTTACATGAAGAAAGCCCAGGACCTA GAAGCTGCCCAGGCATTGGCCCAGAGTGAGAGGAAGCGCCATGAGCTCAACAGGCAGGTCACGGTCCAGCGGAAAGAGAAGGATTTCCAG GGCATGCTGGAGTACCACAAAGAGGACGAGGCCCTCCTCATCCGGAACCTGGTGACAGACTTGAAGCCCCAGATGCTGTCGGGCACAGTG CCCTGTCTCCCCGCCTACATCCTCTACATGTGCATCCGGCACGCGGACTACACCAACGACGATCTCAAGGTGCACTCCCTGCTGACCTCC ACCATCAACGGCATTAAGAAAGTCCTGAAAAAGCACAATGATGACTTTGAGATGACGTCATTCTGGTTATCCAACACCTGCCGCCTTCTT CACTGTCTGAAGCAGTACAGCGGGGATGAGGGCTTCATGACTCAGAACACTGCAAAGCAGAATGAACACTGTCTTAAGAATTTTGACCTC ACCGAATACCGTCAGGTGCTGAGTGACCTTTCCATTCAGATCTACCAGCAGCTCATTAAAATTGCCGAGGGCGTGTTACAGCCGATGATA GTTTCTGCCATGTTGGAAAATGAGAGCATTCAGGGTCTATCTGGTGTGAAGCCCACCGGCTACCGGAAGCGCTCCTCCAGCATGGCAGAT GGGGATAACTCATACTGCCTGGAAGCTATCATCCGCCAGATGAATGCCTTTCATACAGTCATGTGTGACCAGGGCTTGGACCCTGAGATC ATCCTGCAGGTATTCAAACAGCTCTTCTACATGATCAACGCAGTGACTCTTAACAACCTGCTCTTGCGGAAGGACGTCTGCTCTTGGAGC ACAGGCATGCAACTCAGGTACAATATAAGTCAGCTTGAGGAGTGGCTTCGGGGAAGAAACCTTCACCAGAGTGGAGCAGTTCAGACCATG GAACCTCTGATCCAAGCAGCCCAGCTCCTGCAATTAAAGAAGAAAACCCAGGAGGACGCAGAGGCTATCTGCTCCCTGTGTACCTCCCTC AGCACCCAGCAGATTGTCAAAATTTTAAACCTTTATACTCCCCTGAATGAATTTGAAGAACGGGTAACAGTGGCCTTTATACGAACAATC CAGGCACAACTACAAGAGCGGAATGACCCTCAGCAACTGCTATTAGATGCCAAGCACATGTTTCCTGTTTTGTTTCCATTTAATCCATCT TCTCTAACCATGGACTCAATCCACATCCCAGCGTGTCTCAATCTGGAATTCCTCAATGAAGTCTGAAGATGCATGTTTCCAGCATTAGTT TGATTCCCAATGTGAGCAAGAAGGAAGTATATACAGTAAAGTAAATTCAAGGATCTGTTAAATCTGGTAAAAGTAGATCAAATCAGAGAT TGACAGCCTGTGGAGGGTGCTGAACTATACAGAATTAGACACAACTATGTCATTATTTTTTGTACCTACTGCTCAGAATAAAAACACTTG AAATATGGAAGATTTTAAGTTTGATTTCAGTCCAACACATATACATAATTTATAGACACCAAGCAGTCCCCATAGACATATAAAAGGTGT CAATTCTATAAAACGAAGCTGCCTAGTTTTGATCTTTGCATAGAACTAGAGAATGTCCAAATTAAAATACCAAATATATATAAGTCACAT AAATTGCCTTCAAAGGGCTTTAACAAATAATGGTACTAATAACCATGATAATGGCATATACTGACATTTCCCAAAGTTTGCAAACCATAG GTGTGGTTGAGTTTGTGGTGAGATGTTTTAAGAACAAAAATATGGGGATGAGACTTCTGAGAAATATTCCCAAAATATTTTTTAATGGCT GATTATACACAGACAGTGGTGTAACTGACCTCCAGACCAGACATTTTGAGTACTGGTTTCTGAAGCAAAATTAGAAGTGCCAGTCCTCAG TGTGCTCAAACGCTTTTGTGTTATCTTGATTTAATGGAAGAGATTATTAAAATGCTGCTATCCCAAACTCCAAGTGAGAAAGATGGAAAA ATATTTTGTTTCTGATGCTAGTCCATACACTTTCCAAGTCCCACAAAACTTTCACAAAAATGTATATAAGCTAAATATTAGAAACGGATA ACAAACTTGTTTTATTTATAGATGTAAAAACCAAACAAGTCAATATGAAAGCTTTTAATCTCTTAATACCATTAAGCTTCCAGTAAGAGC ATCACATAATGCTCTACTGTTCCAGAAACCAAATAGTAAAACAAACTAAAGTTCGCACATCAGATCATCTGAAAAACCTTCAAAAATAAT CAGTTCAGGGATATTATACAAAAGTTTGGGTTTTTTTTTTTTAAGAGAATAAAATGGCTTAGGTCAACTTTCCCTTTTCAGGTTATTTTC AACGTTTTTCAAATTTAGCACACAAAAAATTGTAAATATCTCTCCCACAAAATAAGGATTTTAAAAAAGTAATTCAGTAATATAACAGGC TTAGATGTTTGCTGCTCTTAGAATTTTTTTTAACTTGTTTTTGGTTTCTTCAAAAGCAAGCATTCAATTGGAAACCCATATTCTTTCCAC ACTTTTTTTTACTGTCTTTTCTGTATTTCTTGATAGCAGTATGCTGTTCCCATAAGAAAAAAATGGTATTTGCAAATCATGGAAGAACAG CCTCTGTATTACATTGAGAAAATAAGATTTATCCATGAATTGGAAGTAGAACAGCCTGCCTTCACCCTCTTTTACTCAACCACCCAACTT AAAAGGCTCTTGGAAACACAGCACACTCCACGCTACCTTCTGCACTGTGCCCTTAGAGCACAGCTTCCTCAGTTGTTCTCTGCATCTCCT GGGGCTTAGGCCAGTCTTAGCCTGGGTTAAGGCTGCTGACATTGTGTTCCAATCAGTTGTCATGGGCATTATCCCCTCTACATCCACATT AAACATGCCGGCTTCTCTTGGGCATCGGCAGAGCTGTGCCTTTTTCTTTCAGTTACAGTTACATAATCACTGACGTCCATGACACTTACC CATGGATCCATGTGCTGACTTCATTTAGAAGGCCAATCTAAAACAACTGGGTTTGTGGCTACCTCTTTAAAGTTGTTTGTGAAGGATAAT TTGTTTTTTAATGCACTTTAGTTTGAAAGTGAGTCTCTTATGTAAGGACCATCCTTAAAAGACCAAAAATGCCTTGTTAGAGTGTTAAGG AGTTTTGACATGCAGTGGTTCCACAAACACAGTGGCTTACTATCCTTATACACTGTCTTATACCATCATTCTCTCCATCTCTCTTGGTCA CTACTCTCTGCTGTCACTGGTTAATCACTAGGTGCCAAGAGCTTACTGAATAAAAGCTTGGCAATTAGAATAAATGGGGAGGGAAGGACC TTATGAATAGTCCATTTAGCCTAAGAAATGGCAGATTTAGTTCTTCTCTTCCAAAAGATAAAGGTATATCCTGGAATTGTACTTAAAACT TACAGATGACTAACAAATATATACTTTATATGTAGTTAATATTTAGATCTGTCTTATTTAATACTTGGAGGCTAGAAGAAGCATCTTTAG GGGAACTATATAATCTTTTGTTAGCATTTTCTCTGCATTTTAAAAAATCATTTCAATTCAAACATTTATCAGTGTCATGAAATCAGTAAT GACTCTTTAACAATTCAGGTTTGAACTCTGCATTAGATGTCTCTTTAATTTTTTAATATTTAAAATTTAGTTGACATTTTTTTCACCAGG TGCCTTTAGCGGTTACTAAGATAACTGACATCAGTTGTTTCTCTGAAATAAGTGTTGCTGTGGGAATAATTTTAATGTTCAAGGTGATAT CATGGGGGAGTTTTGTCTTTTAAAACATTAGAAGCATTTTAAATATTAAGAATCAAATATTTATAGATCAAAACTTGTGTTTTAAGTATT ATACGGGACCTGTTTACTTATAGTAAATGTGAATGTACACATGAGTTGTTGCTGAAGCTGACAAGCATATTACATACATGCATTTTCCCT GTGCCCTCATAGTTGCAGTTAGAGTTCCAGTACCTGTAGGCTCACCTGGGAGGCAGATTAGACCCAAAGGTAGATGTTTTTCCCCTTTCC ATGAAGCATGTCAGTGGGAGTTGCTTCCTTTGATTTCCCTAGTACTAAATTTTAAGGCTTTTGTAAAAACAAAACAAAACTAGGAGCTTG GAACAGTTAAAAATCAACACTGCTACCATCAATTCATCAAATATTTACTTAGAGCTTTCATACATTAAGATTCCAGTAACCAATAAATTA GAATTCATTTCTTCTGCATAAAGTAAATTTTCATACACTTGACCTACTAAGACAGCAAGGGTGTCCTAAATTGAGGCATTTGTATAATGC CTGCATAACTAAATGGTCACTAAAATGGGACAGCATGGGGCAAGACCTTGTAGTTCTTCACAGAATATTTGTGGTCAGTTTCTCCAATTA ATTTGCTGCATGAGCCAAATAACCATAATTCACTTTTTATACCCACTGGTGCCATAATTAGAGAATTAGAGGGTGTAGACAGAGGTTAAT GCCAATGAGAAACACAGGACAGGGTTTTTTTTATTATAAAGGTCATTAGATACAAAAGATTGTTTTTCAAAAAATTTCTAATTCTAACAA AGGGGATCAATCAGAAATGAAACTAAGCTACTTTCTAAAGTGACACTGTATCAGAATAATCCAGATTTGAATATAACATTTTGCCACCAA CTGACATTTAGATGAAGGACTGCCTCTCTGAAAGAGTTCAGATCATATTCAGGGGTGAATCCAACACCATGGAAGAAAGACTACTGATGA AAATATTTTCCCACTTTGCACAAATCTGTAAACTACACCTTTGTTTATAGAAAAATGCTTGTAATAGTCACTGTAATATTTAGCTGTGGA >In-frame_MIB1_ENST00000261537_chr18_19438607_+_MYO5B_ENST00000324581_chr18_47406825_-_5779nt TGCCCGCTCTCCGCCGCCGCCTCCGAGCAGCCGCGGGCCGCCCTCCACTCCGAGCGGGGGGCGCGGCGGCGACAGCTGGGCAGCGGCTTT GGGCTCCGCGGGGACCGCGCCGCCGCCCCCGTGAGTTATTCTCACGTCCCCCGGGGCTCGCTGCCGCCCCCGCCGACGCCTAGAGTCCGG CCCGGGCCCAACTCCCTCACGGGCCCCCCGGCGGCAGCGGCGGCGGCGGCGGCGGCAGCGGCGGAGCCCACCGCCCGGGCCCCGATGAGT AACTCCCGGAATAACCGGGTGATGGTGGAAGGGGTTGGCGCTCGGGTAGTGCGCGGCCCGGACTGGAAGTGGGGGAAGCAGGACGGCGGC GAGGGCCATGTGGGCACCGTCCGGAGCTTCGAGAGCCCCGAGGAGGTGGTGGTAGTGTGGGACAACGGCACAGCTGCCAACTACCGCTGC TCCGGGGCTTACGACCTCCGCATCCTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACCATGTGTGATACCTGCCGCCAGCAACCA ATCATTGGCATTCGATGGAAGTGTGCAGAGTGTACAAATTATGATTTGTGCACAGTGTGTTATCATGGAGATAAACATCATTTAAGACAT CGCTTTTACCGAATTACTACACCGGGAAGTGAGAGGGTTCTGTTAGAGTCTCGTAGGAAATCTAAGAAGATTACAGCCAGAGGAATCTTT GCAGGTGCCAGAGTGGTGCGAGGAGTGGACTGGCAGTGGGAAGATCAAGATGGAGGAAATGGACGTAGGGGAAAGGTAACAGAAATCCAG GACTGGAGTGCATCAAGCCCACATAGCGCAGCATATGTCCTCTGGGATAATGGTGCTAAGAACCTTTACAGAGTTGGCTTTGAGGGCATG TCTGATCTGAAATGTGTCCAGGATGCCAAGGGAGGTTCTTTCTACAGAGATCACTGCCCTGTGCTAGGTGAGCAGAATGGCAACAGGAAT CCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGATCTCGACCTCGAAATTGTACAGTCTTTGCAGCATGGTCATGGAGGATGGACT GATGGAATGTTTGAGACTTTAACTACAACTGGAACTGTTTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGTGGCAAT AGGTGGACCTTCAATCCTGCTGTTCTCACTAAAGCGAACATTGTCCGAAGTGGAGATGCTGCTCAGGGTGCAGAAGGAGGCACCTCGCAG TTTCAAGTGGGTGATCTTGTACAAGTTTGTTATGACCTGGAACGAATTAAACTTCTACAAAGAGGACATGGAGAATGGGCTGAAGCGATG CTTCCAACTTTAGGTAAAGTTGGCCGAGTACAACAGATTTATTCAGACAGTGATTTAAAGGTGGAAGTTTGTGGAACATCTTGGACATAC AATCCAGCAGCAGTTTCCAAGGTGGCATCTGCAGGATCAGCCATTAGCAATGCATCTGGTGAAAGACTCTCACAACTCCTGAAGAAATTA TTTGAAACCCAAGAATCTGGTGACCTCAATGAAGAATTAGTTAAGGCTGCTGCCAATGGAGATGTTGCTAAAGTGGAAGATTTGCTTAAA AGACCAGATGTGGATGTAAATGGGCAATGTGCTGGCCACACAGCTATGCAAGCTGCTAGTCAGAATGGACATGTTGACATTTTGAAGTTA CTTTTGAAGCAAAACGTGGATGTCGAAGCAGAGGATAAAGATGGTGATAGAGCAGTTCACCATGCAGCTTTTGGAGATGAAGGCGCTGTT ATAGAAGTACTACATCGAGGTAGTGCTGATTTGAATGCTCGAAACAAGCGCCGACAGACACCACTTCATATTGCTGTCAATAAAGGTCAT CTTCAAGTTGTGAAGACTTTATTGGACTTTGGCTGTCATCCCAGTCTCCAGGATTCTGAAGGTGATACCCCTCTTCATGATGCAATAAGT AAGAAACGTGATGATATCCTAGCAGTTCTTTTGGAAGCTGGAGCAGATGTTACCATCACAAACAATAATGGATTTAATGCTCTGCATCAT GCTGCACTAAGGGGAAATCCCAGTGCAATGCGTGTTTTACTATCTAAATTACCAAGACCATGGATTGTGGATGAGAAGAAAGATGATGGT TATACTGCCTTACATCTGGCTGCCCTTAATAATCACGTAGAAGTGGCTGAACTGTTGGTACATCAGGGTAATGCAAACCTGGATATCCAG AATGTGAACCAACAAACTGCCCTACACCTTGCTGTTGAACGACAGCATACCCAGATTGTTAGGCTTTTGGTCCGTGCAGGTGCCAAGCTT GATATTCAGGATAAGGATGGGGATACTCCTTTGCATGAAGCTCTAAGGCATCACACTTTGTCTCAGCTACGTCAGCTCCAAGATATGCAA GATGTGGGGAAGGTGGATGCTGCCTGGGAGCCATCCAAAAACACGTTAATAATGGGACTTGGTACCCAGGGGGCAGAGAAGAAGAGTGCA GCATCTATTGCCTGTTTCTTGGCAGCCAATGGTGCTGACCTGAGCATTCGAAATAAGAAGGGTCAATCGCCACTTGATCTCTGTCCTGAT CCGAATCTCTGCAAAGCACTGGCAAAGTGTCATAAGGAAAAAGTCAGTGGTCAAGTGGGTTCTCGGAGTCCTTCTATGATTAGTAATGAT TCTGAAACCTTAGAAGAGTGTATGGTGTGCTCAGATATGAAGAGAGATACTCTTTTTGGTCCATGTGGACATATTGCTACCTGTTCTTTA TGTTCTCCACGTGTCAAGAAATGCCTCATCTGTAAAGAACAGGTTCAATCCAGGACAAAGATTGAAGAATGTGTGGTATGCTCTGACAAG AAAGCAGCTGTTCTTTTTCAACCCTGTGGCCACATGTGTGCTTGTGAGAACTGTGCTAACCTGATGAAAAAGTGTGTGCAGTGTCGAGCA GTAGTTGAACGAAGAGTGCCTTTCATTATGTGCTGTGGAGGGAAAAGTTCAGAAGATGCCACTGATGATATCTCAAGTGGGAATATTCCA GTATTACAAAAGGACAAGGATAATACCAATGTCAATGCAGATGTGCAAAAGTTGCAGCAACAGTTACAAGACATTAAAGAGCAGCGAGTT GCAGACCTGGAGCAAGAAAATGCTCTCTTGAAAGATGAGAAAGAACAGCTCAACAACCAAATCCTGTGCCAGTCTAAAGATGAATTTGCC CAGAACTCTGTGAAGGAAAATCTCATGAAGAAAGAACTGGAGGAGGAGCGATCCCGGTACCAGAACCTTGTGAAGGAATATTCACAGTTG GAGCAGAGATACGACAACCTTCGGGATGAAATGACCATCATAAAGCAAACTCCAGGTCATAGGCGGAACCCATCAAACCAAAGTAGCTTA GAATCTGACTCCAATTACCCCTCCATCTCCACATCTGAGATCGGAGACACTGAGGATGCCCTCCAGCAGGTGGAGGAAATTGGCCTGGAG AAGGCAGCCATGGACATGACGGTCTTCCTGAAGCTGCAGAAGAGAGTACGGGAGCTGGAGCAGGAGAGGAAAAAGCTGCAAGTGCAGCTG GAGAAGAGAGAACAGCAGGACAGCAAGAAAGTCCAGGCGGAACCACCACAGACTGACATAGATTTGGACCCGAATGCAGATCTGGCCTAC AATAGTCTGAAGAGGCAAGAGCTGGAGTCAGAGAACAAAAAGCTGAAGAATGACCTGAATGAGCTGAGGAAAGCCGTGGCCGACCAAGCC ACGCAGAATAACTCCAGCCACGGCTCCCCAGATAGCTACAGCCTCCTGCTGAACCAGCTCAAGCTGGCCCACGAGGAGCTCGAGGTGCGC AAGGAGGAGGTGCTCATCCTCAGGACCCAGATCGTGAGCGCCGACCAGCGGCGACTCGCCGGCAGGAACGCGGAGCCGAACATTAATGCC AGATCAAGTTGGCCTAACAGTGAAAAGCATGTTGACCAGGAGGATGCCATTGAGGCCTATCACGGGGTCTGCCAGACAAACAGGCTGCTG GAGGCTCAGCTGCAGGCCCAGAGCCTGGAGCATGAGGAGGAGGTGGAGCATCTCAAGGCTCAGCTCGAGGCCCTGAAGGAGGAGATGGAC AAACAGCAGCAGACCTTCTGCCAGACGCTACTGCTCTCCCCAGAGGCCCAGGTGGAATTCGGCGTTCAGCAGGAAATATCCCGGCTGACC AACGAGAATCTGGACCTTAAAGAACTGGTAGAAAAGCTGGAAAAGAATGAGAGGAAGCTCAAAAAGCAACTGAAGATTTACATGAAGAAA GCCCAGGACCTAGAAGCTGCCCAGGCATTGGCCCAGAGTGAGAGGAAGCGCCATGAGCTCAACAGGCAGGTCACGGTCCAGCGGAAAGAG AAGGATTTCCAGGGCATGCTGGAGTACCACAAAGAGGACGAGGCCCTCCTCATCCGGAACCTGGTGACAGACTTGAAGCCCCAGATGCTG TCGGGCACAGTGCCCTGTCTCCCCGCCTACATCCTCTACATGTGCATCCGGCACGCGGACTACACCAACGACGATCTCAAGGTGCACTCC CTGCTGACCTCCACCATCAACGGCATTAAGAAAGTCCTGAAAAAGCACAATGATGACTTTGAGATGACGTCATTCTGGTTATCCAACACC TGCCGCCTTCTTCACTGTCTGAAGCAGTACAGCGGGGATGAGGGCTTCATGACTCAGAACACTGCAAAGCAGAATGAACACTGTCTTAAG AATTTTGACCTCACCGAATACCGTCAGGTGCTGAGTGACCTTTCCATTCAGATCTACCAGCAGCTCATTAAAATTGCCGAGGGCGTGTTA CAGCCGATGATAGTTTCTGCCATGTTGGAAAATGAGAGCATTCAGGGTCTATCTGGTGTGAAGCCCACCGGCTACCGGAAGCGCTCCTCC AGCATGGCAGATGGGGATAACTCATACTGCCTGGAAGCTATCATCCGCCAGATGAATGCCTTTCATACAGTCATGTGTGACCAGGGCTTG GACCCTGAGATCATCCTGCAGGTATTCAAACAGCTCTTCTACATGATCAACGCAGTGACTCTTAACAACCTGCTCTTGCGGAAGGACGTC TGCTCTTGGAGCACAGGCATGCAACTCAGGTACAATATAAGTCAGCTTGAGGAGTGGCTTCGGGGAAGAAACCTTCACCAGAGTGGAGCA GTTCAGACCATGGAACCTCTGATCCAAGCAGCCCAGCTCCTGCAATTAAAGAAGAAAACCCAGGAGGACGCAGAGGCTATCTGCTCCCTG TGTACCTCCCTCAGCACCCAGCAGATTGTCAAAATTTTAAACCTTTATACTCCCCTGAATGAATTTGAAGAACGGGTAACAGTGGCCTTT ATACGAACAATCCAGGCACAACTACAAGAGCGGAATGACCCTCAGCAACTGCTATTAGATGCCAAGCACATGTTTCCTGTTTTGTTTCCA TTTAATCCATCTTCTCTAACCATGGACTCAATCCACATCCCAGCGTGTCTCAATCTGGAATTCCTCAATGAAGTCTGAAGATGCATGTTT CCAGCATTAGTTTGATTCCCAATGTGAGCAAGAAGGAAGTATATACAGTAAAGTAAATTCAAGGATCTGTTAAATCTGGTAAAAGTAGAT CAAATCAGAGATTGACAGCCTGTGGAGGGTGCTGAACTATACAGAATTAGACACAACTATGTCATTATTTTTTGTACCTACTGCTCAGAA |
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FusionGenePPI for MIB1_MYO5B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MIB1 | UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2N, UBE2U, UBE2W, UBC, JAG1, RYK, DLL1, AZI2, TBK1, PCM1, SNX5, DAPK1, CMIP, SMN1, CEP131, BLM, MIB1, USP9X, ZFC3H1, RANGAP1, ZBTB10, GEMIN4, MCM3, TOP3A, DDB1, TOP3B, RBBP4, MCM7, CDC27, CEP250, FSD1, PLK4, NTRK1, CENPJ, MED4, CEP290, CEP162, SSX2IP, CEP128, CNTRL, POC5, PCNT, PRKAR2B, OFD1, DYNLL1, PER3, CEP135, FGFR1OP, MAPRE1, CCDC14, PTPN22, TPTE2, LRRCC1, CHRNA3, FAM171B, ANKRD55, LPXN, EPN3, EPB41L4A, EPB41L5 | MYO5B | CXCR2, RAB11FIP2, KIAA1549, COIL, PAN2, RAB11A, RAB11B, RAB25, RAB8A, POLR1C, BNIP2, TCF4, AMOTL2, TRIM54, CCDC8, PEX19, LRRC39, TMOD1, CAPZB, CAPZA2, DBN1, MYH9, PPP1CB, IQGAP1, SYNPO, LIMA1, ANLN, MYO19, SKA3, MYO18A, EXOC6, SYTL4, RAB3B, STX3, TBC1D30, EVI5, SSH1, TMOD3, DKK3, MYL2, PPP6R2, PDF, RAC1, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MIB1_MYO5B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MIB1_MYO5B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MIB1 | C0036572 | Seizures | 1 | CTD_human |
| Hgene | MIB1 | C3554496 | LEFT VENTRICULAR NONCOMPACTION 7 | 1 | UNIPROT |
| Tgene | MYO5B | C0341306 | Microvillus inclusion disease | 5 | CTD_human;ORPHANET;UNIPROT |
| Tgene | MYO5B | C0011991 | Diarrhea | 1 | CTD_human |
| Tgene | MYO5B | C0021831 | Intestinal Diseases | 1 | CTD_human |
| Tgene | MYO5B | C0023903 | Liver neoplasms | 1 | CTD_human |
| Tgene | MYO5B | C0025521 | Inborn Errors of Metabolism | 1 | CTD_human |
| Tgene | MYO5B | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | MYO5B | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
| Tgene | MYO5B | C0525045 | Mood Disorders | 1 | PSYGENET |
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