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Fusion gene ID: 21784 |
FusionGeneSummary for MFSD8_HIPK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MFSD8_HIPK2 | Fusion gene ID: 21784 | Hgene | Tgene | Gene symbol | MFSD8 | HIPK2 | Gene ID | 256471 | 28996 |
| Gene name | major facilitator superfamily domain containing 8 | homeodomain interacting protein kinase 2 | |
| Synonyms | CCMD|CLN7 | PRO0593 | |
| Cytomap | 4q28.2 | 7q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | major facilitator superfamily domain-containing protein 8ceroid-lipofuscinosis, neuronal 7, late infantile | homeodomain-interacting protein kinase 2hHIPk2 | |
| Modification date | 20180524 | 20180522 | |
| UniProtAcc | Q8NHS3 | Q9H2X6 | |
| Ensembl transtripts involved in fusion gene | ENST00000296468, ENST00000515130, ENST00000513559, ENST00000541133, | ENST00000406875, ENST00000428878, ENST00000342645, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 5 X 2=50 |
| # samples | 1 | 5 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(5/50*10)=0 | |
| Context | PubMed: MFSD8 [Title/Abstract] AND HIPK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | HIPK2 | GO:0006468 | protein phosphorylation | 19448668 |
| Tgene | HIPK2 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 14647468 |
| Tgene | HIPK2 | GO:0045766 | positive regulation of angiogenesis | 19046997 |
| Tgene | HIPK2 | GO:0060395 | SMAD protein signal transduction | 12874272 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | STAD | TCGA-BR-7704-01A | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296468 | ENST00000406875 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| In-frame | ENST00000296468 | ENST00000428878 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| In-frame | ENST00000296468 | ENST00000342645 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| 5UTR-3CDS | ENST00000515130 | ENST00000406875 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| 5UTR-3CDS | ENST00000515130 | ENST00000428878 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| 5UTR-3CDS | ENST00000515130 | ENST00000342645 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000513559 | ENST00000406875 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000513559 | ENST00000428878 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000513559 | ENST00000342645 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000541133 | ENST00000406875 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000541133 | ENST00000428878 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
| Frame-shift | ENST00000541133 | ENST00000342645 | MFSD8 | chr4 | 128870959 | - | HIPK2 | chr7 | 139305309 | - |
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FusionProtFeatures for MFSD8_HIPK2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MFSD8 | HIPK2 |
| May be a carrier that transport small solutes by usingchemiosmotic ion gradients. {ECO:0000305}. | Serine/threonine-protein kinase involved intranscription regulation, p53/TP53-mediated cellular apoptosis andregulation of the cell cycle. Acts as a corepressor of severaltranscription factors, including SMAD1 and POU4F1/Brn3a andprobably NK homeodomain transcription factors. PhosphorylatesPDX1, ATF1, PML, p53/TP53, CREB1, CTBP1, CBX4, RUNX1, EP300,CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotesapoptosis through the activation of p53/TP53 both at thetranscription level and at the protein level (by phosphorylationand indirect acetylation). The phosphorylation of p53/TP53 may bemediated by a p53/TP53-HIPK2-AXIN1 complex. Involved in theresponse to hypoxia by acting as a transcriptional co-suppressorof HIF1A. Mediates transcriptional activation of TP73. In responseto TGFB, cooperates with DAXX to activate JNK. Negative regulatorthrough phosphorylation and subsequent proteasomal degradation ofCTNNB1 and the antiapoptotic factor CTBP1. In the Wnt/beta-cateninsignaling pathway acts as an intermediate kinase betweenMAP3K7/TAK1 and NLK to promote the proteasomal degradation of MYB.Phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity. Activates CREB1 and ATF1 transcriptionfactors by phosphorylation in response to genotoxic stress. Inresponse to DNA damage, stabilizes PML by phosphorylation. PML,HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. Promotes angiogenesis, and is involvedin erythroid differentiation, especially during fetal livererythropoiesis. Phosphorylation of RUNX1 and EP300 stimulatesEP300 transcription regulation activity. Triggers ZBTB4 proteindegradation in response to DNA damage. Modulates HMGA1 DNA-bindingaffinity. In response to high glucose, triggers phosphorylation-mediated subnuclear localization shifting of PDX1. Involved in theregulation of eye size, lens formation and retinal laminationduring late embryogenesis. {ECO:0000269|PubMed:11740489,ECO:0000269|PubMed:11925430, ECO:0000269|PubMed:12851404,ECO:0000269|PubMed:12874272, ECO:0000269|PubMed:14678985,ECO:0000269|PubMed:17018294, ECO:0000269|PubMed:17960875,ECO:0000269|PubMed:18695000, ECO:0000269|PubMed:18809579,ECO:0000269|PubMed:19015637, ECO:0000269|PubMed:19046997,ECO:0000269|PubMed:19448668, ECO:0000269|PubMed:20307497,ECO:0000269|PubMed:20573984, ECO:0000269|PubMed:20637728,ECO:0000269|PubMed:20980392, ECO:0000269|PubMed:21192925,ECO:0000269|PubMed:22825850}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 13_14 | 66 | 519 | Motif | Note=Dileucine internalization motif |
| Hgene | MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 1_40 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 41_61 | 66 | 519 | Transmembrane | Helical |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 1088_1094 | 539 | 1199 | Compositional bias | Note=Poly-Ala |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 1088_1094 | 539 | 1172 | Compositional bias | Note=Poly-Ala |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 802_805 | 539 | 1199 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 832_835 | 539 | 1199 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 802_805 | 539 | 1172 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 832_835 | 539 | 1172 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 873_980 | 539 | 1199 | Region | Required for localization to nuclear speckles |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 984_1198 | 539 | 1199 | Region | Note=Autoinhibitory domain (AID) |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 873_980 | 539 | 1172 | Region | Required for localization to nuclear speckles |
| Tgene | >HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 984_1198 | 539 | 1172 | Region | Note=Autoinhibitory domain (AID) |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 127_131 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 153_173 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 195_211 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 233_266 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 288_304 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 326_337 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 359_412 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 434_451 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 473_482 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 504_518 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 62_74 | 66 | 519 | Topological domain | Extracellular |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 96_105 | 66 | 519 | Topological domain | Cytoplasmic |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 106_126 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 132_152 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 174_194 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 212_232 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 267_287 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 305_325 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 338_358 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 413_433 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 452_472 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 483_503 | 66 | 519 | Transmembrane | Helical |
| Hgene | >MFSD8 | chr4:128870959 | chr7:139305309 | ENST00000296468 | - | 4 | 13 | 75_95 | 66 | 519 | Transmembrane | Helical |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 199_527 | 539 | 1199 | Domain | Protein kinase |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 199_527 | 539 | 1172 | Domain | Protein kinase |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 205_213 | 539 | 1199 | Nucleotide binding | ATP |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 205_213 | 539 | 1172 | Nucleotide binding | ATP |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 97_230 | 539 | 1199 | Region | Transcriptional corepression |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 97_230 | 539 | 1172 | Region | Transcriptional corepression |
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FusionGeneSequence for MFSD8_HIPK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000406875_chr7_139305309_-_725aa MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKRQIMFPEHGDLQASGEYVXHGEPE QNPFHHARGPQHVHQPDHDLXQPADHCPQPGSLLYQCHYFLSQSRSLHTKLPIYTLPALSGIHGCSGPAEHAPADRNSPDLCPAXPVPAS SHRVSPRLPRLAGLSLXARWLLGANGKCSSHRHSSPRSSASSDPTRSACPAGLAKWDPADPASPSMAATDWSGHPHISAACHRDSRDHGR HPAAGGLEKYACSRKPLXSHHAAACTIDRSCDPSSSTALKCGCGPRDAAAANQHHLLPEEXAAPVICEKCLHLXGVLLSGHQLPTAIQAC QGEHTSPLCHGAQXPGLQHLGHLWVGRRGLQHHPGTAAADNCHSRHSQPHGQRHHHQQXHGRGGGTETRPHQHCLQAKKKRHQLCHSPRL PLLRLLQQHQPLLRAAACWAQQCQCLXHQGEPGESLHGEPPNHHRATPENPGQRSIGGVXXPGASQHQSPLVLLQVQVLQQRDLHQRSLF RELIWSHHLPAAAAGPPLPAAAATQSQPGSAAHHHGPHWEPPKAAGLHHSHHGPGSVLLPAQQPQPRHCAPASGCSRCRCPPPHPAPPLH LHCAGGPGLHRHRGPPGGLARLCAPHRAAHCLPSQHRPPGPREHGPPGPALAHHPPESVSSPICPPDLHQRLASLHRLHWIPTEPRQGQP >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000428878_chr7_139305309_-_698aa MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKRQIMFPEHGDLQASGEYVXHGEPE QNPFHHARGPQHVHQPDHDLXQPADHCPQPALSGIHGCSGPAEHAPADRNSPDLCPAXPVPASSHRVSPRLPRLAGLSLXARWLLGANGK CSSHRHSSPRSSASSDPTRSACPAGLAKWDPADPASPSMAATDWSGHPHISAACHRDSRDHGRHPAAGGLEKYACSRKPLXSHHAAACTI DRSCDPSSSTALKCGCGPRDAAAANQHHLLPEEXAAPVICEKCLHLXGVLLSGHQLPTAIQACQGEHTSPLCHGAQXPGLQHLGHLWVGR RGLQHHPGTAAADNCHSRHSQPHGQRHHHQQXHGRGGGTETRPHQHCLQAKKKRHQLCHSPRLPLLRLLQQHQPLLRAAACWAQQCQCLX HQGEPGESLHGEPPNHHRATPENPGQRSIGGVXXPGASQHQSPLVLLQVQVLQQRDLHQRSLFRELIWSHHLPAAAAGPPLPAAAATQSQ PGSAAHHHGPHWEPPKAAGLHHSHHGPGSVLLPAQQPQPRHCAPASGCSRCRCPPPHPAPPLHLHCAGGPGLHRHRGPPGGLARLCAPHR >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000342645_chr7_139305309_-_445aa MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKRQIMFPEHGDLQASGEYVXHGEPE QNPFHHARGPQHVHQPDHDLXQPADHCPQPGSLLYQCHYFLSQSRSLHTKLPIYTLPALSGIHGCSGPAEHAPADRNSPDLCPAXPVPAS SHRVSPRLPRLAGLSLXARWLLGANGKCSSHRHSSPRSSASSDPTRSACPAGLAKWDPADPASPSMAATDWSGHPHISAACHRDSRDHGR HPAAGGLEKYACSRKPLXSHHAAACTIDRSCDPSSSTALKCGCGPRDAAAANQHHLLPEEXAAPVISKKKRHQLCHSPRLPLLRLLQQHQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000406875_chr7_139305309_-_2176nt ATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACACCTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAG CATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTCTCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATA TGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGCAAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAG CAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACCATGACCTTTAACAACCAGCTGACCACTGTCCACAACCA GGCTCCCTCCTCTACCAGTGCCACTATTTCCTTAGCCAATCCCGAAGTCTCCATACTAAACTACCCATCTACACTCTACCAGCCCTCAGC GGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAGACAGGAACAGCCCAGATTTGTGCCCGGCCTGACCCGTTCCAGCAAGC TCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCTCCCTCTAAGCACGCTGGCTACTCGGTGCGAATGGAAAATGCAGTTCC CATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAACCAGGTCTGCTTGCCCAGCAGGCTTGGCCAAGTGGGACCCAGCAGAT CCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACCCACACATCAGTGCAGCATGCCACCGTGATTCCCGAGACCATGGCAGG CACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGAAGCCATTATAATCCCATCATGCAGCAGCCTGCACTATTGACCGGTCA TGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCCCACGTGATGCGGCAGCAGCCAACCAGCACCACCTCCTCCCGGAAGAG TAAGCAGCACCAGTCATCTGTGAGAAATGTCTCCACCTGTGAGGTGTCCTCCTCTCAGGCCATCAGCTCCCCACAGCGATCCAAGCGTGT CAAGGAGAACACACCTCCCCGCTGTGCCATGGTGCACAGTAGCCCGGCCTGCAGCACCTCGGTCACCTGTGGGTGGGGCGACGTGGCCTC CAGCACCACCCGGGAACGGCAGCGGCAGACAATTGTCATTCCCGACACTCCCAGCCCCACGGTCAGCGTCATCACCATCAGCAGTGACAC GGACGAGGAGGAGGAACAGAAACACGCCCCCACCAGCACTGTCTCCAAGCAAAGAAAAAACGTCATCAGCTGTGTCACAGTCCACGACTC CCCCTACTCCGACTCCTCCAGCAACACCAGCCCCTACTCCGTGCAGCAGCGTGCTGGGCACAACAATGCCAATGCCTTTGACACCAAGGG GAGCCTGGAGAATCACTGCACGGGGAACCCCCGAACCATCATCGTGCCACCCCTGAAAACCCAGGCCAGCGAAGTATTGGTGGAGTGTGA TAGCCTGGTGCCAGTCAACACCAGTCACCACTCGTCCTCCTACAAGTCCAAGTCCTCCAGCAACGTGACCTCCACCAGCGGTCACTCTTC AGGGAGCTCATCTGGAGCCATCACCTACCGGCAGCAGCGGCCGGGCCCCCACTTCCAGCAGCAGCAGCCACTCAATCTCAGCCAGGCTCA GCAGCACATCACCACGGACCGCACTGGGAGCCACCGAAGGCAGCAGGCCTACATCACTCCCACCATGGCCCAGGCTCCGTACTCCTTCCC GCACAACAGCCCCAGCCACGGCACTGTGCACCCGCATCTGGCTGCAGCCGCTGCCGCTGCCCACCTCCCCACCCAGCCCCACCTCTACAC CTACACTGCGCCGGCGGCCCTGGGCTCCACCGGCACCGTGGCCCACCTGGTGGCCTCGCAAGGCTCTGCGCGCCACACCGTGCAGCACAC TGCCTACCCAGCCAGCATCGTCCACCAGGTCCCCGTGAGCATGGGCCCCCGGGTCCTGCCCTCGCCCACCATCCACCCGAGTCAGTATCC AGCCCAATTTGCCCACCAGACCTACATCAGCGCCTCGCCAGCCTCCACCGTCTACACTGGATACCCACTGAGCCCCGCCAAGGTCAACCA >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000428878_chr7_139305309_-_2095nt ATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACACCTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAG CATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTCTCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATA TGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGCAAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAG CAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACCATGACCTTTAACAACCAGCTGACCACTGTCCACAACCA GCCCTCAGCGGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAGACAGGAACAGCCCAGATTTGTGCCCGGCCTGACCCGTT CCAGCAAGCTCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCTCCCTCTAAGCACGCTGGCTACTCGGTGCGAATGGAAAA TGCAGTTCCCATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAACCAGGTCTGCTTGCCCAGCAGGCTTGGCCAAGTGGGAC CCAGCAGATCCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACCCACACATCAGTGCAGCATGCCACCGTGATTCCCGAGAC CATGGCAGGCACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGAAGCCATTATAATCCCATCATGCAGCAGCCTGCACTATT GACCGGTCATGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCCCACGTGATGCGGCAGCAGCCAACCAGCACCACCTCCTC CCGGAAGAGTAAGCAGCACCAGTCATCTGTGAGAAATGTCTCCACCTGTGAGGTGTCCTCCTCTCAGGCCATCAGCTCCCCACAGCGATC CAAGCGTGTCAAGGAGAACACACCTCCCCGCTGTGCCATGGTGCACAGTAGCCCGGCCTGCAGCACCTCGGTCACCTGTGGGTGGGGCGA CGTGGCCTCCAGCACCACCCGGGAACGGCAGCGGCAGACAATTGTCATTCCCGACACTCCCAGCCCCACGGTCAGCGTCATCACCATCAG CAGTGACACGGACGAGGAGGAGGAACAGAAACACGCCCCCACCAGCACTGTCTCCAAGCAAAGAAAAAACGTCATCAGCTGTGTCACAGT CCACGACTCCCCCTACTCCGACTCCTCCAGCAACACCAGCCCCTACTCCGTGCAGCAGCGTGCTGGGCACAACAATGCCAATGCCTTTGA CACCAAGGGGAGCCTGGAGAATCACTGCACGGGGAACCCCCGAACCATCATCGTGCCACCCCTGAAAACCCAGGCCAGCGAAGTATTGGT GGAGTGTGATAGCCTGGTGCCAGTCAACACCAGTCACCACTCGTCCTCCTACAAGTCCAAGTCCTCCAGCAACGTGACCTCCACCAGCGG TCACTCTTCAGGGAGCTCATCTGGAGCCATCACCTACCGGCAGCAGCGGCCGGGCCCCCACTTCCAGCAGCAGCAGCCACTCAATCTCAG CCAGGCTCAGCAGCACATCACCACGGACCGCACTGGGAGCCACCGAAGGCAGCAGGCCTACATCACTCCCACCATGGCCCAGGCTCCGTA CTCCTTCCCGCACAACAGCCCCAGCCACGGCACTGTGCACCCGCATCTGGCTGCAGCCGCTGCCGCTGCCCACCTCCCCACCCAGCCCCA CCTCTACACCTACACTGCGCCGGCGGCCCTGGGCTCCACCGGCACCGTGGCCCACCTGGTGGCCTCGCAAGGCTCTGCGCGCCACACCGT GCAGCACACTGCCTACCCAGCCAGCATCGTCCACCAGGTCCCCGTGAGCATGGGCCCCCGGGTCCTGCCCTCGCCCACCATCCACCCGAG TCAGTATCCAGCCCAATTTGCCCACCAGACCTACATCAGCGCCTCGCCAGCCTCCACCGTCTACACTGGATACCCACTGAGCCCCGCCAA >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000342645_chr7_139305309_-_1336nt ATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACACCTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAG CATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTCTCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATA TGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGCAAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAG CAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACCATGACCTTTAACAACCAGCTGACCACTGTCCACAACCA GGCTCCCTCCTCTACCAGTGCCACTATTTCCTTAGCCAATCCCGAAGTCTCCATACTAAACTACCCATCTACACTCTACCAGCCCTCAGC GGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAGACAGGAACAGCCCAGATTTGTGCCCGGCCTGACCCGTTCCAGCAAGC TCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCTCCCTCTAAGCACGCTGGCTACTCGGTGCGAATGGAAAATGCAGTTCC CATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAACCAGGTCTGCTTGCCCAGCAGGCTTGGCCAAGTGGGACCCAGCAGAT CCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACCCACACATCAGTGCAGCATGCCACCGTGATTCCCGAGACCATGGCAGG CACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGAAGCCATTATAATCCCATCATGCAGCAGCCTGCACTATTGACCGGTCA TGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCCCACGTGATGCGGCAGCAGCCAACCAGCACCACCTCCTCCCGGAAGAG TAAGCAGCACCAGTCATCTCAAAGAAAAAACGTCATCAGCTGTGTCACAGTCCACGACTCCCCCTACTCCGACTCCTCCAGCAACACCAG CCCCTACTCCGTGCAGCAGCGTGCTGGGCACAACAATGCCAATGCCTTTGACACCAAGGGGAGCCTGGAGAATCACTGCACGGGGAACCC CCGAACCATCATCGTGCCACCCCTGAAAACCCAGGCCAGCGAAGTATTGGTGGAGTGTGATAGCCTGGTGCCAGGTAATTTGGGGCCAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000406875_chr7_139305309_-_13661nt AGGTTACAAGCAGCAGATCCCACCTTCAGTCCTGGCTCTGACAAGCCCTCCAGCTTCACGCCACCCGGGATGGGAGAAAGCAGGTGTCGC GAGAGTTGGGCGCAAGACGCCTTGTAGGGAGTGTAACTATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACAC CTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAGCATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTC TCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATATGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGC AAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAGCAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACC ATGACCTTTAACAACCAGCTGACCACTGTCCACAACCAGGCTCCCTCCTCTACCAGTGCCACTATTTCCTTAGCCAATCCCGAAGTCTCC ATACTAAACTACCCATCTACACTCTACCAGCCCTCAGCGGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAGACAGGAACA GCCCAGATTTGTGCCCGGCCTGACCCGTTCCAGCAAGCTCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCTCCCTCTAAG CACGCTGGCTACTCGGTGCGAATGGAAAATGCAGTTCCCATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAACCAGGTCTG CTTGCCCAGCAGGCTTGGCCAAGTGGGACCCAGCAGATCCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACCCACACATCA GTGCAGCATGCCACCGTGATTCCCGAGACCATGGCAGGCACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGAAGCCATTAT AATCCCATCATGCAGCAGCCTGCACTATTGACCGGTCATGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCCCACGTGATG CGGCAGCAGCCAACCAGCACCACCTCCTCCCGGAAGAGTAAGCAGCACCAGTCATCTGTGAGAAATGTCTCCACCTGTGAGGTGTCCTCC TCTCAGGCCATCAGCTCCCCACAGCGATCCAAGCGTGTCAAGGAGAACACACCTCCCCGCTGTGCCATGGTGCACAGTAGCCCGGCCTGC AGCACCTCGGTCACCTGTGGGTGGGGCGACGTGGCCTCCAGCACCACCCGGGAACGGCAGCGGCAGACAATTGTCATTCCCGACACTCCC AGCCCCACGGTCAGCGTCATCACCATCAGCAGTGACACGGACGAGGAGGAGGAACAGAAACACGCCCCCACCAGCACTGTCTCCAAGCAA AGAAAAAACGTCATCAGCTGTGTCACAGTCCACGACTCCCCCTACTCCGACTCCTCCAGCAACACCAGCCCCTACTCCGTGCAGCAGCGT GCTGGGCACAACAATGCCAATGCCTTTGACACCAAGGGGAGCCTGGAGAATCACTGCACGGGGAACCCCCGAACCATCATCGTGCCACCC CTGAAAACCCAGGCCAGCGAAGTATTGGTGGAGTGTGATAGCCTGGTGCCAGTCAACACCAGTCACCACTCGTCCTCCTACAAGTCCAAG TCCTCCAGCAACGTGACCTCCACCAGCGGTCACTCTTCAGGGAGCTCATCTGGAGCCATCACCTACCGGCAGCAGCGGCCGGGCCCCCAC TTCCAGCAGCAGCAGCCACTCAATCTCAGCCAGGCTCAGCAGCACATCACCACGGACCGCACTGGGAGCCACCGAAGGCAGCAGGCCTAC ATCACTCCCACCATGGCCCAGGCTCCGTACTCCTTCCCGCACAACAGCCCCAGCCACGGCACTGTGCACCCGCATCTGGCTGCAGCCGCT GCCGCTGCCCACCTCCCCACCCAGCCCCACCTCTACACCTACACTGCGCCGGCGGCCCTGGGCTCCACCGGCACCGTGGCCCACCTGGTG GCCTCGCAAGGCTCTGCGCGCCACACCGTGCAGCACACTGCCTACCCAGCCAGCATCGTCCACCAGGTCCCCGTGAGCATGGGCCCCCGG GTCCTGCCCTCGCCCACCATCCACCCGAGTCAGTATCCAGCCCAATTTGCCCACCAGACCTACATCAGCGCCTCGCCAGCCTCCACCGTC TACACTGGATACCCACTGAGCCCCGCCAAGGTCAACCAGTACCCTTACATATAAACACTGGAGGGGAGGGAGGGAGGGAGGGAGGGAGAG AATGGCCCGAGGGAGGAGGGAGAGAAGGAGGGAGGCGCTCCTGGGACCGTGGGCGCTGGCCTTTTATACTGAAGATGCCGCACACAAACA ATGCAAACGGGGCAGGGGCGGGGGGGGGGGGGGGGGCAGAGGGCAGGGGGACGGGTCGGGACACCAGTGAAACTTGAACCGGGAAGTGGG AGGACGTAGAGCAGAGAAGAGAACATTTTTAAAAGGAAGGGATTAAAGAGGGTGGGAAATCTATGGTTTTTATTTTAAAAAAGAAAAAGG AAAAAAAAAAAGTCAATAACAAAAAACCCAGCTCAAGAACCCATTCTACGCCAAACTGGAAAGGAGAAGAGAGCAACAGGAAGATTCCAG AAACGGGGGGCCCCAGTTTTTGAAGAACTTTATGAACTTTTCAAAGATTATTTTCATATGGCAGCAAGTGATACGGAAGACTGCTGTCAG GGACACCTGATATGGAAATCAAATAGATTTTTAATTAATTGAACATAAGATTTAGGGATTTTTCCAGAACTCGAAAGGGTCAACAGCCCT CCAGAATGTCGGGCTGCAGCCTGAGGAGGCTGATGTTTGGAGCTGGTGTGGGATTGGCGAAGCCCAGTCCGGGCTCCCTAGTCAGGAAAG ACGGGGGACGGCCAGGCTGCTGGAAGGCCCCCGGGGGCGCGGGGCGAGTTTTCTTTTTCTGAGCACTCTGGATAAATCCCTAAGCAACGT TGTTTCTCAAATGTCATTAATAATGTGTGTTGCAAACTTTAGGTTTTTTTCTTTTCTGAAAATGTATTTTCTCTTTGAATCCACCCCTAG TCGCGTAGCGTAGGGCTAGCGGTCGTCACAGACACCCTAGTAGAATGTAGCACTCAGCACCCTTGTCTCCTACCTTGTGTTCAACTCCAA TGATACCAATAGAATATTCCTCAATGTAATTGCACAAAAAAAAGCGATATAACATAGGCATGTAACCAATGTGGCGGTGCAGGTGTGCGG GTGAGCGAGCACGTGTGGGTGTGCACGCGCCGCCCTCCCCGCGTGGCCCTCGGCGCCGCCACCCTAGCTGGCGCAGTCTTGACACTGCAT CCTTCCCTCCTAGTGCCTTACCGAGCGACAGACGCGGCGTGAGGGTTTACTTCCACTGGTACTCCAAGAAACTGAGGCTAGTCAGACACA ATCTCAGCTCTTCTGTTGTGCTGTTGTAACAGTTTACGCTGGCCTTTTTTTTTTCTTTTTCTTTTTCTTTTTAAAATGTTAATGCCCGTT GTCTTTCCTGGGCTGTTTGCTAGCGGAAGGATGCCAGGGAAGCCAGCAGGAGCTAGGAGAGAGTCCGTGGATCTCGAAAGAAATATGGGA GACAGATGCCCGGCGGGTGCGTCTGGAGATGGGGACGGCGGGAGTTGAGTTGTGGCAGTAGTTGAGTTGTAATTTGTGGGCGGAGGCCCA GAGAGACTCCCCACCCTTCACCCCTGCCCCACTCTGTCCCCAGTTCCGCCATTTGTGAGGCCAGAGGTTTCCGGACTGTTGGCCTCGCCA GGCAGCCGTCTCCCGCCCCAGGCGGCATCCCCCAGTCCCTCCCGCCTCCACGAGAGCCTGGAGCTCTCAGCCTCGCCCGGGGCTCCACTC TCTCCTCCGGCTCCCTGGGCTGTTTTGCTCTAACGATCTTGCCAGATCCCTCCCTCTGTAGACAACCACCAACCTCTGTTTGCTGTTGAA TTCTCTCCTCACATTACCCAGGTCTGCTCAAGACATGATTTTGGTTTTGGTTTCTGAGGGTTCTAGTGGGCAGAAGGTTGGAGGGACACT TATGAGGGTGGCCGGGGGTCTGACGCTGCACTTTGGAAAAACTCACACAGTTGAATTTCCAAAGAAATCTGCCCTTTGCCCTCTTTGCAC CTTTGATACATTCTGGAAGTTTTCTCAGGCTTTGGACACTTCTGGGGATGGAGGTGTGGAGAAGTGGGGAGTTCCCTCTCTTCATAGTAA ATAACTCTGAAATATGTGAATGTGAATGGCAGGAGAATCTGGCCAAGGATGGGGCCGAAAAGGGTGGTTCTAATTGTTTGCTTCTGATGT TGAGTCTTTAGCTGACCCCACAGGCAGGTTTCCAAGGTGCAAAGAGATCTTTCCCGAGTCAGCGGCCCCATCCTCATCCTCCCTCCCTTT ACTTCCTCACTGTGCAGTCTCCCTCAAGGATCTACTGTGAAAGGTGTGTTTGTAGTGATATCCAACCTAACTCAGTAACGAAGTCGTTAC TTAGCTCTTAGCTGTGAAATAACTCTGGAAACTTCCCCACCCCAACCATAAATTCTTACTTATAAAGAAACAGGTCCCCAAACTGGAAAC AGCTTAGTCCAGGCCTCAGCGAGAAGGAAGGACACCATGACTGCTCCATGCTGGGCACAGCCGGGCAGTCTTGCCAAGTGCCTGCTGGAG GCTGTGCCGGCAAGAGGCCTGCAGCAAGGAGATTCCCTTCCCTCGGGCCATTATCAATACTGTCTTTATCTGGAGGTGGGGAAGCGCAGC CCTCTGAGACAGCAGGACAATGGTCAGTTCAGAGAGGGTGAGGGCAGCAAACGCTTCAGAGGACACAGAAGCCAGAGGACCCCCCCCCGC CCCACAGCTGGGTCAGCCTGGAAAATCCATCTATTAGGGACTTTTTGGCAGCCAGATGGCAGCAATAGCCCATTAGGTCTCATCCCGAGT TCCAAGTCTTGGCTGCAAATGAGCCTCAGTTCGCCTTACTGGAGAGCACCCCCAGATTCCTGGGCACAGTTCATTTCCAGCCCTTTCTAG ATCTGATCTTTTAGGGGGAAAGACAGCTTAAAATGTTCTTTTCATTTTAAAGAAAATTATTCTGTCTGCTTAAGTTGGAGGCTACTTACT CTTTCACCTGACATTTTCTTTCCTTTTATTCTTCCAGATCAGGAATGAAATTTCCATGCTGCTCATAAAGATAATATTATTGTACTAATT ATTTTTATTACCATTGTAATTATGATCATTATGTTGATATTTTAGTCAGGGTTTTAAATGCACATTTATTCCAAGTATCTTTGTGTTTTC TCTTTAATATTTAAACTTATTCTCTCTGTGAGTATATAAGTAGACTGGAGGGACATCCAGATGTCCAGTTTTGTCAGGCAAAAAAAAAAA GGAAAGACTTAGGAAGTAGGAAAATTGTTTCTGTCATCTCTATCCCAACAAGAGACGTCAAGAAAGATCCACCACAGAACAAAAGTTTAA AGAAGAATCAAAGCCTTGATTGGGCTTCTGACAACATGGTCACCATCAAGGTTGTCATTTTCTAGATCCCAGAGGCCTGGGATGCGACGT CAGGTGGCATCTCATGGGCTCGGGGAATGTCGAGTCACTGACTGTCCAGCCCTTAGCCAGCTTCTCTCCCACATCCTCAGAGCTCTCCTG TGCTTCTGAAATCTGTTAACTAAATCTTTGGCTTGCCTCTGGTATTTAAGCAAGAAAATTCCCTCCCAGAGGTGACCCCATCCGCTTCCC CACAATCCATCCTTTTGCCATCGGCGCACCTGGGGCGTGGCTTAGGTTCTTCAATGCAGGGACATTTGCCCCCTCCCAGAAGCTGCTGGG CACAGTGAGGTGGCGTAAGAGTGACTGGCAGGTGGTACCTTCCCCAGGAAATTTCACCACACCACCCAGTTCCTCAGCCTGCCCCCTCCC CCTGTGATGCATGCCCCCAGCACCCAATTCTAGCCAGCTGGAAGTGGGTGGAGGGACAGCAGGAGGCCAGAGAAACCCTGAACAAAGCTG GGCGGCTGCTCAGGCATCACAGGCTGCACCCCCTCTGAAAGCATCCCCACTGGGCTCCGGCCACATCTTCAGTGCACTGTGCTGTGTGCG CTGGGTGCTCACACGCTGTCCCCAGACCCACAAAGTGCTAGGCCCCAGTTGAAGAAAGGGGTGAAATAGCCAGCTTCACCGAAGGGAAGG GAAGGGAAGTATTGGGCGATGCCAGCCCCACAGACGCTCAGCAAACATTAGTGCACATTCTCCTAGTCCTCACCCAATGGCCTCCTCTAC CCCCATGCATGGAGCTGCCACATCAGAAGCCCCAAGAGAAGCTCCCTGCAGGAGAGGCCAGCTCCCTGGATGCCCAATTGCATACCTGGC CGAATCTGCCATTGAGTCACCTTAGCAAATAGGCTGCTGTCACTAGGACCAAGCTCTCAAGCAGAGGGATGCCAACCTAGTCCTTACTTA GCCCACGAATCATCTAGAGCATCCTCTAGTCTTTTGTGGGCTCCCTCCTTCCCATTTGAAGAGACATTGTTCAGAGGAAGAGGGGAAGAT TTGAAATGTCAGGTCACGGAGGAGTGTTTAACTGGAGCCTGGTGAACCGCAGGGCAATTTGCTTCTGCTCACTGGGTTCTGACTGGCCCG TCTGGACGTGGGCCCCCATGTCTCTGTGCTTAGGGCCTCTTCATGATGTTTTGGATGTTTCCAAGGGAAGTGGGTGAGCAGATCAAGGGG TGGGAGAGTCGAGGCTTGATGCCAGTTAATACTGTGAAGTGGAGCGTGCGGTCAGTGGAATTCAGAGGAAAAAGAAGGGTTGGAGCAAAG CGGCATTCATCTCCTGGACTGTTAGCCTTTCTAGTCTTCCTGGTGGCTGAGGTGTTCACGGGCTGGGGGAGCCAGCTGACCTTTGTCCTC TTCAACCTAGAAGACTCAGCCCGCCCAGACACCAACGTGTGAGACGGATGGACATCAGGAAGGGAAGGGGAGATTAGCCCAACTGCTGAC AGAACGATTTCCCTTGGTTGGACCTTGGGAATGGCAAACACTCATATTGGAACAAGCTTGGGGTGGAAGATTTAGGCCGTGTGAGCATGT GTGAGTGAGTGGAACAAACTTTCTTGGAAACTGGAGGGAGGAGATGAGGAGGCTTCGGGAAGTATTACTGATGGCTCATGGTTGAGAGAG CGACGTGGGGACCCAGCTCGCCCCAGCTTTTGTCCCAGGTTCTCTTTGTCTGATGCTGAGGGCAGGGTGGGGTGTGGGACCACCACTCTT GTTGGCCTGTCAAGTAGACCCTAGGACAGAAAATGGAAAGAAGGAAATGGCTCGGTGCTCTCAACTAGCAGAGAGAATTGAGGAGAGGTA AGGGTTCCTTCTGCAGGCCAGCCTGGGACTCCACAGCGCCAGCAGGAGTGACTTGGCCACAAGACATTCCAGCCCCAGGGACTTTGCAGG CTTCATTCCCTGTCTGTGTCTTTTCCTTCTGGTGTGTTTTACAGACTTCTGATGGGGAAGCTTCAAACTTGAGCAGGCCAGAGATGTCCT TACCAAATTGGAAAGGAAGGTGAAACTGTTCCTTTCTTTAGCCAAAGAACCCTTCTCAAAGACGCCTCCAGAAATGGACAAAATGGCCTT CCCTTCGTTCCTTTCCAGGCAATAATGACATCATTAGTGATGCAATTCTATTTGTCTTTCTCTTTCCTCTCTGTCCTTTTTTTTAAAAAA AAAAAATGCATTTATTTCAAAACTGTGCTATTCTTTTAAGAGGAGTGGAGGTGACCCCTTCGATGCTGCTGCTATCGGGAGACAAGGTGC CATACCAATACGTGGGCTTGACTAATCCCAGGCCACCATGGGAGAGAGCAAAGCAGGGCTGCCAGGAGTTCAGTTGCATCAAGGGCGTAG AGCACGCGGGGGCTGGGCTCGGAATAGCAGTACTTTTCCACTTTGATGCCTTAGAACTCTCACTTCTCATCTCCACAGACCAGACTCAGT AAAATCTCAGGCCACTAGAGAATGGAAGGCGGTGAAACAGGATTTAAATGCAAAAAAAACCTATTGGAGGCTTTTGGCACCGTGGCTCAC TAGAGGGACCCAGCATAGTAGAGGTTTCTCTTGTTGCAGCTTCTGAAAAGTTCAAAAAAGAACTCCAGGCCGTTCTTCCCTCAAACCCAG TGAGAGTTTGCAGAGAAGTGCCCCCTGCAGGGCTCCCGTCCCAGAACACCAGCACCAGAGAGGGTCTTCCCGATGCCCCCCGCTGGACTT GCCCAAGCCTCTGGGAGCCCCTCATCTCAGATCCCTGTGTTGAACATGACACTGACTGTCCCTTATTTGTTAAAATTTGCAATATCTCTC AAGTAAATAATAGCCAACATTTGTTGAATGCTTTCATGACTCCCGGGCTAAGGCCTTTATGAGCGTTGTCTCAAGGGGCCCCAACAGCCA TCCCACAGGGAGGGGGATAACAGCCCCCATTTATAGATAAGGGAGCTGACCGGATGCTCTGAGAAGTGGCAGGTGTTGAAGGAAGGATAA AGCAGTGATGGGCCAGAATCCCCAAGGTTCCCTTTTTTGTTCATCAGGCCCTTCCTGAGATGTGATTTTTAATCTTTTAACTTTTTTTAA TTAATAGCAATGCGTGGCCTCATATTTCTATGAACCATTTAGTGATACTCCCGCTTCCTGCATGCCACACACTGTGCTGGGAATTGCTCA TGGGTTGTCCTGTTTCATCTTCTCCGTAGCCCTGTGAGATCGGCAATATTAGTCCCCCTACAGCCAAGGAAACTGCCCAGAGCCACACAA CTCTTGAGGGGCGAGGAGGGCTTGAACCTGAGTCTGCCCAGCTCCAGAACTGAGCTTGCAGCCATTAGCCACAGCTGTCTCCTGCATGTC TGAGCAAAGAAAGGCCTTTACACAGCATCACCCTGTGCCATCCCATGCACCGTGGGACTCAGCTAAAGGACTGTGCAAAGAGGGGGCTCC TGAGTTGGATTTAGGCAAAAGGGGCAGAATTCGTTTGATTTTTAGAGAAAATCTCTGGAGAGTTTCTTTTGATTCATAGAATTCCTTTTA GATTTCTTTCCAGCATACCAACTAGCTTTAGTAGTGCTGCTACAACCAGCTCTTATAAGTAAGAGTGAAAAAGTATTCTTTTCTTCTTTA AAAAATAAGTTTTTCTTGCTTATAGTTAATTCTAGAAAGGCAATACTAAAGGTATATATTTTTTTCAAAATGCTATTTTTTACTGCACTT GATAATTATCCTGACAGCTCTGATCTCTGTAATAGATTCACTCTTCAGCTCTGGGCAGAACCAGAGGCAGGGTTCACACCAAATTTGTAA ATACCATATGTGGGTCTGGTGTCCAGGAACTTTTTTCTTTCTGTTAAAAAAAAGAAAAAAAAAAGAAAAAAAAAAAGAAGTAGAGGTGGA AGAAAGACAAGACTTAGAGGAACAAAAGAATGTTTTCTTTTGAGATACTCTTCTCAAAGAAATAGCAACAATTGTATAAACAGGAAAACC AGCCAGCTTTCATGATAAAAGGAAGGCGTGTCTCTTGCCCTGGTATGAGATTAACAGAAATACAGATGCATTTTTATTTTGATTGAAAGA TGGTGAGAATGTAGAAATGCTTAGGACTAGATTTTTAATTTTTTAAAATAACTATTATCATTTATTATGAAATATTTGTTCAGTTGTTTT GAGTGGGTTTCTTGTTCCTTTTTTCATTTAAAACCTTCTTTGTTGACTGGCTCCAGGCTTGTTTGCCTAAATTCTTAGGTAGTTTACACA AGTTCTAGAATCTTTTAGAACTTTAACTCCATTGGAAGCAAACCTAACTAATCGGAGTTTGAGATCCTGGTTGGTTTCAATAGGTATTCT GGAATTCTGGCAGAACACCTAAAGATTTTTTTTTTTTTTAGAAGGTTTTAGATACATTATCTTACACAAACTGTGACCTAATGGCAATAA TTACCTCAAATGTGGGCATTCATCCTGGTTTTAGCCTTTTTTGAAATCATGTAGCCAGCTTGATCTTGGAATTTAAAGACTATGAATTCT CTGTGGGCTGAAAATAATGATTACTTCATACCCCCGGTCATCGTTGCTTAAGTGAATTCTGAAAATAGCTCATCTTTACAACAAAAATTA AACCAAGGAAGAGATTATTCTTTGTGTGTTGTACTCAAATGCGATGTTCAAATGCACATGTTAAGTATATATGTTTTTAGCTACTGTAAA ATGCTGTTAGCCTTCTAAGCTATCAAAACAGTCACATTTTAAATGAGTAAACTAAACAATTGACTGTGGATACTTAAGCATATTTCTGGC TACGTTTTATAGTTAAAGTGTTTTATAGTTTACATTTAGACTGGTACTTTTTAAAGAAAAGTTCTGTTTATAACTGACATCCGCAAACCC CAGTGAATGCCTCTTAGTTGGAGGTTGTGTCTCCCCCAAGGCAAGTGTGTTGTCCCAGACTCTTCTGTAGTCCAGCATGCGCACTTCCCT CTGGATTATTACTTTCCACGTGAACTCAAGAGAACATGAAAGGCAATCCAGATGGAGGGAAAAGGTGTGAGTCCGCAGCCCGGGCCAGAT GCGAAGGTCTCATGCGTGTCGTCTAAACACTTGTCTTCAAGGCCTTCTCTCTGACATCTTGGAAGAGTCATTGAGAACAGATAACCTGGT TCATTGATTTTTGTCTTGATTTGAATATTTAACTTATTAATAGATCCACTGATTTCCAGGCACCAGGCAGTAGAAGAGACTGGGATTCAG GTGACCATGAAGGCACAGCTGCTACTTCTGGGCCGGGGGTGATATTTTGATCAGCGTTTTGTAGGGGAGGACCATATACCCCTATTCCCA TGGTCGCTGGCTGGGTTTTCCATATATCTGCTGTCATTTATTCGTTTTCCCCTTAAAAGCAAAATCAATGTAAAAGGCTATGTTTACGTT TTACTCATTGTCCAGCTTAGACTCAAAGTCTAGTTCGGTGGGAGGGGGACCTTAGCATCCTCTCAGAGATGGTCAGGGCTGAGCAGGAGG AGGCAGAGACAGAGGGGCAGCTCAGCCTGGTCCATTGAGACCCACTCTAAACAGACATCATATTTGGAACAAGAAGATGCTTCGAGACAG GAATGGGCCCCACTGTCATGCAGAAACAGACTGGGGGAATGGCAGTTTCCCTGAGTCTTGGTTTCTTTTATGTTTTCTCTTGTGCCACCA CCAAACTGCAGAGGACCTGCTGTGACCTAAAGGGCATTCCTTTAGCAGATAAGACCTTGAAAACTGCAAAACACCTGGGACCAGGGAGCT TTTAAAAAATACAAAAAAATACCACATTTGCTTTTTCCCTGTGAACTGTATTGACAGCGTGTTCTTAGGACAGTCTTTTGGTGGAAATGT TACTGTAAAATAGTTTTCATCTCACCCCTCCTAATCATACTCCCACTTTCCTGTTTGTGTGGTGGTGTTGCTGTTTTTTCCTTTACATGA ATTAACCAAATGAATTTTGTGTCATTGTTTTTGGGGCTTATATTTTTAAAACATAGAAATTGCCTTTTGTTCATTTGAAAAGTAAGTATG TTGTATCTGAAAAAGGGCTCTGCCTCTGCTCTCCCTCGCTTCCTTGTAACCAATCTCCAAACGAATCTCTCCTGGCACCGCCCCCTTCCT TATATAGGGTCACTGTCCCCGGGGCCACCTCTGCCTCCACCCTGCTGTCACCACTGCCCTGGGCCAAGGCACCCAGGACTCCCAGAAAGC GCGAGAGCCAGCAAGAAGGCCCCACTCAGCCTTGAGACTGGTGGTCACACCTCCCTGTCAGAGTCGCCTGCTGGGCTGAAGGGGCAATGG ATTGTCATTGTTGAAATTGTTTGGCTCAGGTTATAAGGAGGAACTTGGGAAGTAGAAAGTGACTTGACCATGTGCATCCTTGGTAGCTTC CTGTAACTAACAAATGGAACAGAGAGCACACCCCCGCCCCGCCCCACCCCAAGCAGATGTTCCCGTCAGCGCTGCCCTGAGTCAGTCGGT CCCCCGTTTCTGCTCTCCTCCCTTTTGTGTTCCTGCTCACTTCAAGCTTCTTCCATGGACTTTCCAGGGCACAGTCATCTCTAGCCCCCA AATCATCTCTTCATCCTCTGTGTGTGCATTTTTTTAACCAAATGAAATAGACAAGAAAGTCATACTTTGGGGCAGCAGAATTTCTAATTT AGTAGAATCACTGTATAGAGATAGATGTTGATATATATGTTTGTGTATATATATCAAACCAAATTGGATAGGAGAAGTATAGCTTTACAG ATGAGGAGAAGGAGCTCTTTAGAGGTCGGAGTCAAGACTGGTGTCTTGGACGTGCATGGGCTGTGTCCCAGGCCACTCCGCACACATGGG GCTGAGGCGTGGCGCCGGGCCCTTGTCATCCACCTCACCACGGCAGAGCCAGCAGGCCCTGTAGGGTGCTGCTGCTGTCTCACTGGGTCC CAGCTTCAAGCGCATCAGTGGGTGACGGGGGCAACAAATCAGAGTGACTGGAAGTTTCCATCCCGTTTTGCTTTGACCACGTGTACTGAG CTGCAGCCTCTGATACTCTGTCACGTTTCCAAAAATGGTATCCATTAGGATAGAAAGAGAATGGATCTGCAGAAATGTTTACCTTTCAAC TGCTCATGAATTCAGGACACTGGATAGAAAGACTCACTCCCCAAAATGAGAACAGGGAAGAGGAGACCCGGCGACACTAAGTCACCAGGT CCAAGGAACGTGGCTCCCTCCCCAGGGTCATCTCACCTAGATCTTTCTCTCCCAGGTCATCTCAGCTCAATCTCAATAACCCTATGAAAG CCCTGGTCTGTTGTGTTCCTTCACCGTACGGTTTCTGTAATAAAAAGTGTTAATCCATGTTAATCTGTGTGAAAATTATTGCGTGCAACA GTATTTTCTCGTGTACCTCTTTTTCCTATGTGAATTGTCCCTCTTTTTTATTTATAAATGTCTACTTTTGTTTTTTTAAAGACAAACCAA TGTGTTGTAGACCTATATGTAACCTATTCCTTAGTCTCATATTATAGGTATGTTATAAGAATGGATATTTTACTTGGCTTTAGAATGTTT TACAAGAAAACTAATTCTTAACTGATCAAGTCCTTGCTACTAAAATGCTTGTGTTTTTCATCATGACGTCGTGTGCTTCTAAATTAATCA TTTTCGTTGTAGAAAAATGGAGTGAATTTATATTAGTCTTGGAAACTAATAATAGCATTGTAAATTTATGAGATGATTTTAACAGAAAAA ATATAGAAGAATATAGTTATTTTAATTGTAATATTACTAACTGTAGGGTGAGAAAAAGGGGGGGGGGTCCCATTGTGGTGAACTATGTTA TAGCTTGTTACTCATAGTTTCTTTTTGATCATTTTTTCGGTCTCCGAGGTGAAATGACTTATTAATTAAAATTTGTAAACTCACATATGC >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000428878_chr7_139305309_-_2521nt AGGTTACAAGCAGCAGATCCCACCTTCAGTCCTGGCTCTGACAAGCCCTCCAGCTTCACGCCACCCGGGATGGGAGAAAGCAGGTGTCGC GAGAGTTGGGCGCAAGACGCCTTGTAGGGAGTGTAACTATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACAC CTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAGCATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTC TCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATATGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGC AAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAGCAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACC ATGACCTTTAACAACCAGCTGACCACTGTCCACAACCAGCCCTCAGCGGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAG ACAGGAACAGCCCAGATTTGTGCCCGGCCTGACCCGTTCCAGCAAGCTCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCT CCCTCTAAGCACGCTGGCTACTCGGTGCGAATGGAAAATGCAGTTCCCATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAA CCAGGTCTGCTTGCCCAGCAGGCTTGGCCAAGTGGGACCCAGCAGATCCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACC CACACATCAGTGCAGCATGCCACCGTGATTCCCGAGACCATGGCAGGCACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGA AGCCATTATAATCCCATCATGCAGCAGCCTGCACTATTGACCGGTCATGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCC CACGTGATGCGGCAGCAGCCAACCAGCACCACCTCCTCCCGGAAGAGTAAGCAGCACCAGTCATCTGTGAGAAATGTCTCCACCTGTGAG GTGTCCTCCTCTCAGGCCATCAGCTCCCCACAGCGATCCAAGCGTGTCAAGGAGAACACACCTCCCCGCTGTGCCATGGTGCACAGTAGC CCGGCCTGCAGCACCTCGGTCACCTGTGGGTGGGGCGACGTGGCCTCCAGCACCACCCGGGAACGGCAGCGGCAGACAATTGTCATTCCC GACACTCCCAGCCCCACGGTCAGCGTCATCACCATCAGCAGTGACACGGACGAGGAGGAGGAACAGAAACACGCCCCCACCAGCACTGTC TCCAAGCAAAGAAAAAACGTCATCAGCTGTGTCACAGTCCACGACTCCCCCTACTCCGACTCCTCCAGCAACACCAGCCCCTACTCCGTG CAGCAGCGTGCTGGGCACAACAATGCCAATGCCTTTGACACCAAGGGGAGCCTGGAGAATCACTGCACGGGGAACCCCCGAACCATCATC GTGCCACCCCTGAAAACCCAGGCCAGCGAAGTATTGGTGGAGTGTGATAGCCTGGTGCCAGTCAACACCAGTCACCACTCGTCCTCCTAC AAGTCCAAGTCCTCCAGCAACGTGACCTCCACCAGCGGTCACTCTTCAGGGAGCTCATCTGGAGCCATCACCTACCGGCAGCAGCGGCCG GGCCCCCACTTCCAGCAGCAGCAGCCACTCAATCTCAGCCAGGCTCAGCAGCACATCACCACGGACCGCACTGGGAGCCACCGAAGGCAG CAGGCCTACATCACTCCCACCATGGCCCAGGCTCCGTACTCCTTCCCGCACAACAGCCCCAGCCACGGCACTGTGCACCCGCATCTGGCT GCAGCCGCTGCCGCTGCCCACCTCCCCACCCAGCCCCACCTCTACACCTACACTGCGCCGGCGGCCCTGGGCTCCACCGGCACCGTGGCC CACCTGGTGGCCTCGCAAGGCTCTGCGCGCCACACCGTGCAGCACACTGCCTACCCAGCCAGCATCGTCCACCAGGTCCCCGTGAGCATG GGCCCCCGGGTCCTGCCCTCGCCCACCATCCACCCGAGTCAGTATCCAGCCCAATTTGCCCACCAGACCTACATCAGCGCCTCGCCAGCC TCCACCGTCTACACTGGATACCCACTGAGCCCCGCCAAGGTCAACCAGTACCCTTACATATAAACACTGGAGGGGAGGGAGGGAGGGAGG GAGGGAGAGAATGGCCCGAGGGAGGAGGGAGAGAAGGAGGGAGGCGCTCCTGGGACCGTGGGCGCTGGCCTTTTATACTGAAGATGCCGC ACACAAACAATGCAAACGGGGCAGGGGCGGGGGGGGGGGGGGGGGCAGAGGGCAGGGGGACGGGTCGGGACACCAGTGAAACTTGAACCG GGAAGTGGGAGGACGTAGAGCAGAGAAGAGAACATTTTTAAAAGGAAGGGATTAAAGAGGGTGGGAAATCTATGGTTTTTATTTTAAAAA >In-frame_MFSD8_ENST00000296468_chr4_128870959_-_HIPK2_ENST00000342645_chr7_139305309_-_1464nt AGGTTACAAGCAGCAGATCCCACCTTCAGTCCTGGCTCTGACAAGCCCTCCAGCTTCACGCCACCCGGGATGGGAGAAAGCAGGTGTCGC GAGAGTTGGGCGCAAGACGCCTTGTAGGGAGTGTAACTATGGCCGGCCTGCGGAACGAAAGTGAACAGGAGCCGCTCTTAGGCGACACAC CTGGAAGCAGAGAATGGGACATTTTAGAGACTGAAGAGCATTATAAGAGCCGATGGAGATCTATTAGGATTTTATATCTTACTATGTTTC TCAGCAGTGTAGGGTTTTCTGTAGTGATGATGTCCATATGGCCATATCTCCAAAAGCGTCAAATCATGTTTCCAGAACATGGAGATCTGC AAGCGTCGGGTGAATATGTATGACACGGTGAACCAGAGCAAAACCCCTTTCATCACGCACGTGGCCCCCAGCACGTCCACCAACCTGACC ATGACCTTTAACAACCAGCTGACCACTGTCCACAACCAGGCTCCCTCCTCTACCAGTGCCACTATTTCCTTAGCCAATCCCGAAGTCTCC ATACTAAACTACCCATCTACACTCTACCAGCCCTCAGCGGCATCCATGGCTGCAGTGGCCCAGCGGAGCATGCCCCTGCAGACAGGAACA GCCCAGATTTGTGCCCGGCCTGACCCGTTCCAGCAAGCTCTCATCGTGTGTCCCCCCGGCTTCCAAGGCTTGCAGGCCTCTCCCTCTAAG CACGCTGGCTACTCGGTGCGAATGGAAAATGCAGTTCCCATCGTCACTCAAGCCCCAGGAGCTCAGCCTCTTCAGATCCAACCAGGTCTG CTTGCCCAGCAGGCTTGGCCAAGTGGGACCCAGCAGATCCTGCTTCCCCCAGCATGGCAGCAACTGACTGGAGTGGCCACCCACACATCA GTGCAGCATGCCACCGTGATTCCCGAGACCATGGCAGGCACCCAGCAGCTGGCGGACTGGAGAAATACGCATGCTCACGGAAGCCATTAT AATCCCATCATGCAGCAGCCTGCACTATTGACCGGTCATGTGACCCTTCCAGCAGCACAGCCCTTAAATGTGGGTGTGGCCCACGTGATG CGGCAGCAGCCAACCAGCACCACCTCCTCCCGGAAGAGTAAGCAGCACCAGTCATCTCAAAGAAAAAACGTCATCAGCTGTGTCACAGTC CACGACTCCCCCTACTCCGACTCCTCCAGCAACACCAGCCCCTACTCCGTGCAGCAGCGTGCTGGGCACAACAATGCCAATGCCTTTGAC ACCAAGGGGAGCCTGGAGAATCACTGCACGGGGAACCCCCGAACCATCATCGTGCCACCCCTGAAAACCCAGGCCAGCGAAGTATTGGTG GAGTGTGATAGCCTGGTGCCAGGTAATTTGGGGCCAGGACAGGGCAGGAACCTCTCCCTGGAGAGTGGTTTTCCTGCTTTTCTGCTGCTA |
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FusionGenePPI for MFSD8_HIPK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MFSD8 | HLA-DQA1, ASGR2, P2RY12, ZACN, LPAR1, EPHX1, TPRA1, CYB5R1, FPR2, CD97, PTPRN, TNFSF8, SLC22A9, PTGIR, IPPK, GPR114, SLC22A16, C3AR1, EBP, DNAJC19, GPR21, YIPF3 | HIPK2 | DAXX, SP100, UBE2I, SUMO1, SKI, SMAD1, SMAD2, SMAD3, TP53INP1, TP53, CREBBP, RANBP9, NKX2-1, TRADD, TP73, TP63, FBXW7, BTRC, CUL1, MYB, RUNX1, EP300, HIPK2, NLK, MAP3K7, MYBL1, MYBL2, WSB1, SIAH1P1, SIAH1, SIAH2, CXCL1, AXIN1, HIST2H2BE, SENP2, SENP1, FBXO3, PML, CBX4, PAX6, CHMP4B, DCAF7, DYRK1A, DYRK1B, MAP3K1, MDM2, ZBTB4, MECP2, MBP, MKNK1, AATF, XAF1, SUMO2, SUMO3, RGMA, ABL1, PARP1, HSPA1A, STUB1, LZTS2, ACTBL2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 935_1049 | 539 | 1199 | AXIN1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 935_1049 | 539 | 1172 | AXIN1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 774_876 | 539 | 1199 | CTBP1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 774_876 | 539 | 1172 | CTBP1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 787_897 | 539 | 1199 | HMGA1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 787_897 | 539 | 1172 | HMGA1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 752_897 | 539 | 1199 | POU4F1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 752_897 | 539 | 1172 | POU4F1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 539_844 | 539 | 1199 | SKI and SMAD1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 539_844 | 539 | 1172 | SKI and SMAD1 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 846_941 | 539 | 1199 | TP53 and TP73 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 846_941 | 539 | 1172 | TP53 and TP73 |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 873_907 | 539 | 1199 | UBE2I |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 873_907 | 539 | 1172 | UBE2I |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000406875 | - | 5 | 15 | 189_520 | 539 | 1199 | DAXX |
| Tgene | HIPK2 | chr4:128870959 | chr7:139305309 | ENST00000428878 | - | 5 | 15 | 189_520 | 539 | 1172 | DAXX |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MFSD8_HIPK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MFSD8_HIPK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MFSD8 | C1838571 | Ceroid Lipofuscinosis, Neuronal, 7 | 7 | CTD_human;ORPHANET;UNIPROT |
| Hgene | MFSD8 | C4015371 | MACULAR DYSTROPHY WITH CENTRAL CONE INVOLVEMENT | 1 | UNIPROT |
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