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FusionGeneSummary

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Fusion gene ID: 21758

FusionGeneSummary for MFN1_KMT2C

check button Fusion gene summary
Fusion gene informationFusion gene name: MFN1_KMT2C
Fusion gene ID: 21758
HgeneTgene
Gene symbol

MFN1

KMT2C

Gene ID

55669

58508

Gene namemitofusin 1lysine methyltransferase 2C
Synonymshfzo1|hfzo2HALR|KLEFS2|MLL3
Cytomap

3q26.33

7q36.1

Type of geneprotein-codingprotein-coding
Descriptionmitofusin-1fzo homologmitochondrial transmembrane GTPase FZO-2mitochondrial transmembrane GTPase Fzo-1putative transmembrane GTPasetransmembrane GTPase MFN1histone-lysine N-methyltransferase 2CALR-like proteinhistone-lysine N-methyltransferase MLL3histone-lysine N-methyltransferase, H3 lysine-4 specifichomologous to ALR proteinlysine (K)-specific methyltransferase 2Cmyeloid/lymphoid or mixed-lineage le
Modification date2018052320180523
UniProtAcc

Q8IWA4

Q8NEZ4

Ensembl transtripts involved in fusion geneENST00000280653, ENST00000471841, 
ENST00000263969, 		ENST00000262189, 
ENST00000355193, ENST00000485655, 
ENST00000485241, 
Fusion gene scores* DoF score2 X 1 X 2=49 X 13 X 6=702
# samples 215
** MAII scorelog2(2/4*10)=2.32192809488736log2(15/702*10)=-2.22650852980868
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MFN1 [Title/Abstract] AND KMT2C [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMFN1

GO:0008053

mitochondrial fusion

20436456

HgeneMFN1

GO:0046039

GTP metabolic process

27920125


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUSCTCGA-L3-A524-01AMFN1chr3

179069823

+KMT2Cchr7

151921264

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000280653ENST00000262189MFN1chr3

179069823

+KMT2Cchr7

151921264

-
In-frameENST00000280653ENST00000355193MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000280653ENST00000485655MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000280653ENST00000485241MFN1chr3

179069823

+KMT2Cchr7

151921264

-
In-frameENST00000471841ENST00000262189MFN1chr3

179069823

+KMT2Cchr7

151921264

-
In-frameENST00000471841ENST00000355193MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000471841ENST00000485655MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000471841ENST00000485241MFN1chr3

179069823

+KMT2Cchr7

151921264

-
In-frameENST00000263969ENST00000262189MFN1chr3

179069823

+KMT2Cchr7

151921264

-
In-frameENST00000263969ENST00000355193MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000263969ENST00000485655MFN1chr3

179069823

+KMT2Cchr7

151921264

-
5CDS-intronENST00000263969ENST00000485241MFN1chr3

179069823

+KMT2Cchr7

151921264

-

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FusionProtFeatures for MFN1_KMT2C


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MFN1

Q8IWA4

KMT2C

Q8NEZ4

Mitochondrial outer membrane GTPase that mediatesmitochondrial clustering and fusion (PubMed:12475957,PubMed:12759376, PubMed:27920125, PubMed:28114303). Membraneclustering requires GTPase activity (PubMed:27920125). It mayinvolve a major rearrangement of the coiled coil domains(PubMed:27920125, PubMed:28114303). Mitochondria are highlydynamic organelles, and their morphology is determined by theequilibrium between mitochondrial fusion and fission events(PubMed:12475957, PubMed:12759376). Overexpression induces theformation of mitochondrial networks (in vitro) (PubMed:12759376).Has low GTPase activity (PubMed:27920125, PubMed:28114303).{ECO:0000269|PubMed:12475957, ECO:0000269|PubMed:12759376,ECO:0000269|PubMed:27920125, ECO:0000269|PubMed:28114303}. Histone methyltransferase. Methylates 'Lys-4' of histoneH3. H3 'Lys-4' methylation represents a specific tag forepigenetic transcriptional activation. Central component of theMLL2/3 complex, a coactivator complex of nuclear receptors,involved in transcriptional coactivation. KMT2C/MLL3 may be acatalytic subunit of this complex. May be involved inleukemogenesis and developmental disorder.{ECO:0000269|PubMed:17500065}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+2179_7382742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+3169_7382631RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+3189_7382742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591338_136610524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591754_178710524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18593054_308110524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18593173_327210524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18593391_343310524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601338_136610524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601754_178710524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18603054_308110524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18603173_327210524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18603391_343310524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591719_179610524912Compositional biasNote=Gln-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591834_228110524912Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18592412_263010524912Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18592690_278610524912Compositional biasNote=Asp-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18593012_350910524912Compositional biasNote=Gln-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18593277_338110524912Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601719_179610524969Compositional biasNote=Gln-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601834_228110524969Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18602412_263010524969Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18602690_278610524969Compositional biasNote=Asp-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18603012_350910524969Compositional biasNote=Gln-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18603277_338110524969Compositional biasNote=Pro-rich
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594545_460510524912DomainFYR N-terminal
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594606_469110524912DomainFYR C-terminal
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594771_488710524912DomainSET
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594895_491110524912DomainPost-SET
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604545_460510524969DomainFYR N-terminal
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604606_469110524969DomainFYR C-terminal
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604771_488710524969DomainSET
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604895_491110524969DomainPost-SET
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594848_484910524912RegionS-adenosyl-L-methionine binding
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604848_484910524969RegionS-adenosyl-L-methionine binding
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591084_113910524912Zinc fingerPHD-type 7
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594399_443910524912Zinc fingerC2HC pre-PHD-type 2
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18594460_450710524912Zinc fingerPHD-type 8
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601084_113910524969Zinc fingerPHD-type 7
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604399_443910524969Zinc fingerC2HC pre-PHD-type 2
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18604460_450710524969Zinc fingerPHD-type 8

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217371_40882742Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217679_73482742Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316371_40882631Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316679_73482631Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318371_40882742Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318679_73482742Coiled coilOntology_term=ECO:0000255
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+21772_32182742DomainDynamin-type G
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+31672_32182631DomainDynamin-type G
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+31872_32182742DomainDynamin-type G
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+21785_9082742Nucleotide bindingGTP
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+31685_9082631Nucleotide bindingGTP
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+31885_9082742Nucleotide bindingGTP
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217108_10982742RegionG2 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217178_18182742RegionG3 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217237_24082742RegionG4 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217266_26682742RegionG5 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217338_36482742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217703_73482742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+21782_8982742RegionG1 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316108_10982631RegionG2 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316178_18182631RegionG3 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316237_24082631RegionG4 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316266_26682631RegionG5 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316338_36482631RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316703_73482631RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+31682_8982631RegionG1 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318108_10982742RegionG2 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318178_18182742RegionG3 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318237_24082742RegionG4 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318266_26682742RegionG5 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318338_36482742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318703_73482742RegionPart of a helix bundle domain%2C formed by helices from N-terminal and C-terminal regions
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+31882_8982742RegionG1 motif
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+2171_58482742Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217606_60882742Topological domainMitochondrial intermembrane
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217630_74182742Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+3161_58482631Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316606_60882631Topological domainMitochondrial intermembrane
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316630_74182631Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+3181_58482742Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318606_60882742Topological domainMitochondrial intermembrane
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318630_74182742Topological domainCytoplasmic
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217585_60582742TransmembraneHelical%3B Name%3D1
HgeneMFN1chr3:179069823chr7:151921264ENST00000263969+217609_62982742TransmembraneHelical%3B Name%3D2
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316585_60582631TransmembraneHelical%3B Name%3D1
HgeneMFN1chr3:179069823chr7:151921264ENST00000280653+316609_62982631TransmembraneHelical%3B Name%3D2
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318585_60582742TransmembraneHelical%3B Name%3D1
HgeneMFN1chr3:179069823chr7:151921264ENST00000471841+318609_62982742TransmembraneHelical%3B Name%3D2
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859644_67210524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-185992_11210524912Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860644_67210524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-186092_11210524969Coiled coilOntology_term=ECO:0000255
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-185934_4610524912DNA bindingNote=A.T hook
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-186034_4610524969DNA bindingNote=A.T hook
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859436_48910524912DomainDHHC
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860436_48910524969DomainDHHC
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-18591007_105710524912Zinc fingerPHD-type 6
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859227_26210524912Zinc fingerC2HC pre-PHD-type 1%3B degenerate
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859283_33110524912Zinc fingerPHD-type 1
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859341_39110524912Zinc fingerPHD-type 2
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859344_38910524912Zinc fingerRING-type
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859388_43810524912Zinc fingerPHD-type 3
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859464_52010524912Zinc fingerPHD-type 4
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000262189-1859957_101010524912Zinc fingerPHD-type 5
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-18601007_105710524969Zinc fingerPHD-type 6
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860227_26210524969Zinc fingerC2HC pre-PHD-type 1%3B degenerate
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860283_33110524969Zinc fingerPHD-type 1
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860341_39110524969Zinc fingerPHD-type 2
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860344_38910524969Zinc fingerRING-type
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860388_43810524969Zinc fingerPHD-type 3
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860464_52010524969Zinc fingerPHD-type 4
TgeneKMT2Cchr3:179069823chr7:151921264ENST00000355193-1860957_101010524969Zinc fingerPHD-type 5


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FusionGeneSequence for MFN1_KMT2C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_3942aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTK
TLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPE
PVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPD
VPSMGLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGV
RKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKAS
PPASPPIAFPPAFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSL
KPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCT
NIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFH
SPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG
EDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPY
SKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLT

>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_3999aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQVRQLSLLPLMEPIIGVNFAHFLPYGSGQFNSGNRLLGTFGSATLEGVSDY
YSQLIYKQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPA
SLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLY
FASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSAN
PPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCF
ILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEAKPDELKVTVKLKP
RLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLD
LDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHE
QELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIE
EKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGR
NPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGL
GLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSS

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_3942aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTK
TLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPE
PVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPD
VPSMGLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGV
RKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKAS
PPASPPIAFPPAFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSL
KPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCT
NIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFH
SPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG
EDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPY
SKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLT

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_3999aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQVRQLSLLPLMEPIIGVNFAHFLPYGSGQFNSGNRLLGTFGSATLEGVSDY
YSQLIYKQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPA
SLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLY
FASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSAN
PPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCF
ILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEAKPDELKVTVKLKP
RLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLD
LDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHE
QELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIE
EKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGR
NPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGL
GLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSS

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_3942aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTK
TLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPE
PVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPD
VPSMGLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGV
RKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKAS
PPASPPIAFPPAFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSL
KPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCT
NIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFH
SPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG
EDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPY
SKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLT

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_3999aa
MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDC
CESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGE
LMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTL
VDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTK
SGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLY
KIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDK
NSAFNPMASDPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQER
APYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQ
QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ
AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP
PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRP
VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRIS
EGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAH
DVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQD
SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV
PPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRH
GNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQ
PSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKK
SMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNH
VSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ
NRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMG
QVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAK
KAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ
LQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERER
KERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ
GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGH
SYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPN
MAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQR
SKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQVRQLSLLPLMEPIIGVNFAHFLPYGSGQFNSGNRLLGTFGSATLEGVSDY
YSQLIYKQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPA
SLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLY
FASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSAN
PPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCF
ILYSSTAQAKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEAKPDELKVTVKLKP
RLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLD
LDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKPKGIHE
QELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIE
EKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGR
NPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGL
GLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_11826nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCT
ATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAA
ACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGAT
GTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGT
TTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAA
CCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGC
ACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCT
GCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGAT
GTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGA
TCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATAT
AAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTG
CGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAAT
AACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGA
GAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCT
CCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAG
CTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGG
AGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTT
AAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTC
AACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTG
GAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACC
AACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGA
ATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAA
CGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCAT
TCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGC
TCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCT
AAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGA
GAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGA
TACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAG
AGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTAT
AGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATT
CAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCC
AACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACA
GGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATC
AGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCAC

>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_11997nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCTCTAATGGAACCAATCATTGGAGTGAACTTTGCGCAC
TTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACTTTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTAC
TATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGT
CAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGA
CCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCC
TCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCC
TCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCG
TCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATAT
TTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAAC
ATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCC
ATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAAC
CCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCT
AGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCT
TTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTT
ATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCT
TCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCC
TCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCT
CGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCAT
ATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGAT
CCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGAC
TTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCT
CTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTAT
CACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAG
CAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAA
CGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAA
GCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAG
GAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTC
TGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTG
TTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGA
AATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTG
TTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAG
TTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTG
GGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAA
GAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCC
GCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGT
CGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGCT

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_11826nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCT
ATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAA
ACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGAT
GTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGT
TTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAA
CCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGC
ACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCT
GCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGAT
GTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGA
TCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATAT
AAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTG
CGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAAT
AACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGA
GAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCT
CCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAG
CTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGG
AGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTT
AAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTC
AACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTG
GAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACC
AACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGA
ATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAA
CGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCAT
TCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGC
TCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCT
AAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGA
GAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGA
TACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAG
AGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTAT
AGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATT
CAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCC
AACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACA
GGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATC
AGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCAC

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_11997nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCTCTAATGGAACCAATCATTGGAGTGAACTTTGCGCAC
TTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACTTTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTAC
TATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGT
CAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGA
CCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCC
TCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCC
TCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCG
TCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATAT
TTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAAC
ATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCC
ATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAAC
CCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCT
AGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCT
TTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTT
ATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCT
TCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCC
TCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCT
CGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCAT
ATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGAT
CCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGAC
TTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCT
CTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTAT
CACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAG
CAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAA
CGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAA
GCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAG
GAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTC
TGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTG
TTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGA
AATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTG
TTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAG
TTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTG
GGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAA
GAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCC
GCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGT
CGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGCT

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_11826nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCT
ATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAA
ACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGAT
GTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGT
TTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAA
CCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGC
ACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCT
GCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGAT
GTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGA
TCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATAT
AAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTG
CGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAAT
AACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGA
GAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCT
CCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAG
CTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGG
AGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTT
AAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTC
AACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTG
GAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACC
AACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGA
ATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAA
CGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCAT
TCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGC
TCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCT
AAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGA
GAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGA
TACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAG
AGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTAT
AGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATT
CAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCC
AACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACA
GGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATC
AGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCAC

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_11997nt
ATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACT
GAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATAT
AAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGT
GGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGC
TATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAG
GAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGC
TGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACT
GAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAAT
CAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAA
CTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTC
AAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGA
TCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTTA
GTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCT
GCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGA
GCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAA
TCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGAT
GATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCA
CGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATAT
AAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAG
CCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCT
CATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAA
AATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTCG
AATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAAT
TTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGA
GCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAA
CAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAA
TGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAG
CAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTG
ACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCT
ACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAG
GCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAA
ATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATCA
TCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAAT
GACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTT
TCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAA
AGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCT
CCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGA
CCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCC
CATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCT
GTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACT
GTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCT
GATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCA
GAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCT
TTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTT
TCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCAT
GATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCT
GGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAA
TTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGAC
TCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCT
GGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTT
GCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTG
CCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACAA
ATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAA
CTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACAT
GGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCT
GTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAAC
CATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAG
CCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAA
GACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACT
AATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAA
AGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAA
AACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAAT
TCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCA
GACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGT
GCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGT
TTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCAT
GTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAAC
CATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCA
ACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAG
AATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGA
CAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAA
ATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGC
CAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCT
AGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTG
CTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAG
AAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAG
ATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATG
ATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAG
CTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCT
CCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTC
TCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGT
AAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAA
ATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGT
GATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAA
GGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCA
TCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGG
CCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACAC
AGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAG
AAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACT
ACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAAT
ATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCA
AATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGC
CAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCC
CATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTG
AATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTG
CAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGA
AGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCT
AGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCTCTAATGGAACCAATCATTGGAGTGAACTTTGCGCAC
TTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACTTTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTAC
TATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGT
CAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGA
CCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCC
TCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCC
TCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCG
TCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATAT
TTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAAC
ATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCC
ATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAAC
CCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCT
AGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCT
TTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTT
ATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCT
TCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCC
TCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCT
CGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCAT
ATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGAT
CCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGAC
TTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCT
CTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTAT
CACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAG
CAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAA
CGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAA
GCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAG
GAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTC
TGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTG
TTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGA
AATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTG
TTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAG
TTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTG
GGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAA
GAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCC
GCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGT
CGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGCT


* Fusion transcript sequences (Full-length transcript).
>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_13859nt
AGTGACCGCCCTTTGCCACTCCCCCTGCCTCCTCTCCGCCTTTAACTTCTCGGGAAGATGAGGCAGTTTGGCATCTGTGGCCGAGTTGCT
GTTGCCGGGTGATAGTTGGAGCGGAGACTTAGCATAATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATT
ACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACTGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATA
GCCACTGAAGATGATCTGGTAGAAATGCAAGGATATAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTG
GCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGTGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGC
GCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGCTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGA
TGGATGCATGCAGTTTGTCAGAACTTAAATACTGAGGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCC
TATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCA
CCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAA
CGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCA
AGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGAT
GATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGG
CAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGA
GATGATGGCTGGAGTGAGCAGTTACCAGATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATAC
CGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCTGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAA
AGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGAGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTA
GATCCACTACTTAGTTCATCCTCGGCTCCAACAAAATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTA
AACACAGATGATGACATTCTTGGAATAATTTCAGATGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCT
TCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAA
ATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTT
AGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGG
ATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCA
ATTGCACAATCCTCTTATCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCA
GCTCCCACTGTGGAAGGAGAAAATGACACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATG
GCAACTGTTGCCCCAGTTCTCTACACCAATATTAATTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATT
GCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGAGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAA
GTACAGATGTCAAATGATTCCATGAAAAGGCAGCAACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGAT
CCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAA
GCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGT
TCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAA
CTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCC
CCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAAC
TCACGACCACCATCTCCAATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAAT
TCTGCTGCACCAGTGGAAAACTGTACACCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCT
GTCAGAGATTTATGTTCTTCTTCCACGACAAATAATGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTT
CCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTTTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACT
AAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAAAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGT
GGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCT
GTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCC
CTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAG
GACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCT
TACTCTCAACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGAC
TTGTTTGTTACACCTGTAACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTAC
TCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGAT
CCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCTTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCC
CCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTTTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCT
CAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCATGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCA
AACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAG
AATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAG
AAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTT
AACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTC
CCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGT
CATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTA
TCTGTAGATATGCCTAGGCCTTTAAATAACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTT
CAGCAGCACAACATACTGGGCCAAGCATATATTGAACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCT
GGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACATGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATG
CGACGACCTCCCCAGGGTCTACCTAATCAGCTACCTGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCT
GTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCT
GAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAA
CTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAG
GTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCA
TATACAGATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAG
TGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTT
ACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAAT
GTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCAGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTT
GAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGTGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCT
TGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGTTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCA
CCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCC
ATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCA
ACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCC
CAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTT
TTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGAT
TTTGATGCAATTACAGATCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATG
CCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCC
ATTCCTCAGGATGGCAGTATAACACATCAGATTTCTAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAG
CAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTGCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCT
AAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAGAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACT
GAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAA
CAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACC
ATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGA
ATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTA
CCAATAAAAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAAC
AATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAG
GTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTG
TCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGTGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAA
ATGGGGCAGGTTTTACAGCAGCAGAATATACAACAAGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGG
CAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAAT
CTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTC
CCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCA
GAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGAT
ATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAA
GAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGAT
TTCTCACAAGCAACTCCAAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATA
AAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCT
GTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCCCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAA
CACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTGAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAAT
AAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTGCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCA
AAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGG
AAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCA
ACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGA
AAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTG
GCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATA
CAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTAT
CCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCA
GAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGT
CTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGA
ATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTAT
CGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTA
CCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGT
TGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACC
AAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAG
GAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGAT
GTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTC
GAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTC
AATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAA
ATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAA
GGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAG
GTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACG
GGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGAC
AAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAG
CGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATT
GGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGC
ACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAA
GGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCT
GAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTT
CCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGT
GCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTT
CAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAA
TGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATT
GAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGC
ATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAA
GTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTT
GACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGC
TCAGCGGGCGGCTTGTCCCTAGGAAGAGGCGATTCAACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGA
CTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTG
AAGTGGCCGAGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGT
TTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTG
CCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAA
GGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAG
CTAAGGGATAATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGA
AACTTTTGTATTTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACT
AACAAACCCTGTTACTTTGTACAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCT
GCAGCAGCTCGGGGGCTTATAAAATGTTCATAGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACC
AAAATTTCAACCTAGAGTGTTGGGGGTTTTTTGGAAACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGG
GGCGTATGCTACGACTACAACTTTTATAGCTGTTTTGGTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGT
CAGGTTTTTTTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAA
GTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGC
CTTCTATTTAACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTT
TGGAAGATGTAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAA
ACTTAATCAGCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGT
TTTGTGTGCACAATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCT
TACAGAATAAATCAATTGTATATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATAT
CCTGACATCCTACCAGTATTTGTCCTACCGGGTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTT

>In-frame_MFN1_ENST00000280653_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_14026nt
AGTGACCGCCCTTTGCCACTCCCCCTGCCTCCTCTCCGCCTTTAACTTCTCGGGAAGATGAGGCAGTTTGGCATCTGTGGCCGAGTTGCT
GTTGCCGGGTGATAGTTGGAGCGGAGACTTAGCATAATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATT
ACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACTGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATA
GCCACTGAAGATGATCTGGTAGAAATGCAAGGATATAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTG
GCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGTGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGC
GCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGCTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGA
TGGATGCATGCAGTTTGTCAGAACTTAAATACTGAGGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCC
TATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCA
CCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAA
CGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCA
AGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGAT
GATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGG
CAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGA
GATGATGGCTGGAGTGAGCAGTTACCAGATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATAC
CGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCTGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAA
AGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGAGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTA
GATCCACTACTTAGTTCATCCTCGGCTCCAACAAAATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTA
AACACAGATGATGACATTCTTGGAATAATTTCAGATGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCT
TCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAA
ATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTT
AGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGG
ATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCA
ATTGCACAATCCTCTTATCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCA
GCTCCCACTGTGGAAGGAGAAAATGACACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATG
GCAACTGTTGCCCCAGTTCTCTACACCAATATTAATTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATT
GCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGAGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAA
GTACAGATGTCAAATGATTCCATGAAAAGGCAGCAACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGAT
CCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAA
GCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGT
TCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAA
CTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCC
CCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAAC
TCACGACCACCATCTCCAATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAAT
TCTGCTGCACCAGTGGAAAACTGTACACCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCT
GTCAGAGATTTATGTTCTTCTTCCACGACAAATAATGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTT
CCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTTTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACT
AAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAAAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGT
GGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCT
GTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCC
CTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAG
GACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCT
TACTCTCAACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGAC
TTGTTTGTTACACCTGTAACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTAC
TCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGAT
CCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCTTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCC
CCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTTTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCT
CAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCATGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCA
AACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAG
AATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAG
AAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTT
AACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTC
CCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGT
CATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTA
TCTGTAGATATGCCTAGGCCTTTAAATAACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTT
CAGCAGCACAACATACTGGGCCAAGCATATATTGAACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCT
GGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACATGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATG
CGACGACCTCCCCAGGGTCTACCTAATCAGCTACCTGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCT
GTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCT
GAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAA
CTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAG
GTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCA
TATACAGATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAG
TGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTT
ACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAAT
GTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCAGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTT
GAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGTGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCT
TGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGTTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCA
CCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCC
ATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCA
ACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCC
CAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTT
TTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGAT
TTTGATGCAATTACAGATCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATG
CCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCC
ATTCCTCAGGATGGCAGTATAACACATCAGATTTCTAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAG
CAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTGCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCT
AAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAGAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACT
GAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAA
CAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACC
ATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGA
ATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTA
CCAATAAAAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAAC
AATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAG
GTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTG
TCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGTGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAA
ATGGGGCAGGTTTTACAGCAGCAGAATATACAACAAGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGG
CAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAAT
CTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTC
CCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCA
GAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGAT
ATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAA
GAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGAT
TTCTCACAAGCAACTCCAAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATA
AAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCT
GTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCCCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAA
CACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTGAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAAT
AAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTGCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCA
AAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGG
AAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCT
CTAATGGAACCAATCATTGGAGTGAACTTTGCGCACTTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACT
TTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTACTATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCT
GCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGA
GTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCT
CTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCAC
TGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTG
TCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGA
AGGAATGACATCAAAACTGAGCCAGGCACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCT
GTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAAC
AGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCAT
TTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCT
CCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGT
AAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTA
GAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATT
CCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGT
CTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAG
CCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAA
TGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAA
TTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGA
TTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAG
ACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACT
AGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATG
CTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAG
GTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTG
CTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTAT
GCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAA
GACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTC
CAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTT
GAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCT
GAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACA
GTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCC
AATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATC
GGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAAC
GACCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACT
TTTGAGAGAGGACACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAA
GATGACCAGCACAAGATTCCGTGTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGC
GGCTTGTCCCTAGGAAGAGGCGATTCAACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAA
AAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCG
AGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTT
CCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTGCCCTGCCCC
GGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAAGGGGCAGGC
CCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAGCTAAGGGAT
AATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGAAACTTTTGT
ATTTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAACCC
TGTTACTTTGTACAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCT
CGGGGGCTTATAAAATGTTCATAGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCA
ACCTAGAGTGTTGGGGGTTTTTTGGAAACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGC
TACGACTACAACTTTTATAGCTGTTTTGGTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTT
TTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTG
ATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGCCTTCTATTT
AACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTTTGGAAGATG
TAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAAACTTAATCA
GCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGTTTTGTGTGC
ACAATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAATA
AATCAATTGTATATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATC
CTACCAGTATTTGTCCTACCGGGTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATA

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_13859nt
AGTGACCGCCCTTTGCCACTCCCCCTGCCTCCTCTCCGCCTTTAACTTCTCGGGAAGATGAGGCAGTTTGGCATCTGTGGCCGAGTTGCT
GTTGCCGGGTGATAGTTGGAGCGGAGACTTAGCATAATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATT
ACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACTGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATA
GCCACTGAAGATGATCTGGTAGAAATGCAAGGATATAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTG
GCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGTGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGC
GCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGCTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGA
TGGATGCATGCAGTTTGTCAGAACTTAAATACTGAGGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCC
TATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCA
CCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAA
CGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCA
AGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGAT
GATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGG
CAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGA
GATGATGGCTGGAGTGAGCAGTTACCAGATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATAC
CGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCTGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAA
AGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGAGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTA
GATCCACTACTTAGTTCATCCTCGGCTCCAACAAAATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTA
AACACAGATGATGACATTCTTGGAATAATTTCAGATGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCT
TCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAA
ATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTT
AGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGG
ATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCA
ATTGCACAATCCTCTTATCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCA
GCTCCCACTGTGGAAGGAGAAAATGACACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATG
GCAACTGTTGCCCCAGTTCTCTACACCAATATTAATTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATT
GCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGAGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAA
GTACAGATGTCAAATGATTCCATGAAAAGGCAGCAACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGAT
CCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAA
GCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGT
TCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAA
CTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCC
CCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAAC
TCACGACCACCATCTCCAATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAAT
TCTGCTGCACCAGTGGAAAACTGTACACCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCT
GTCAGAGATTTATGTTCTTCTTCCACGACAAATAATGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTT
CCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTTTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACT
AAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAAAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGT
GGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCT
GTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCC
CTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAG
GACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCT
TACTCTCAACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGAC
TTGTTTGTTACACCTGTAACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTAC
TCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGAT
CCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCTTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCC
CCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTTTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCT
CAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCATGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCA
AACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAG
AATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAG
AAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTT
AACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTC
CCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGT
CATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTA
TCTGTAGATATGCCTAGGCCTTTAAATAACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTT
CAGCAGCACAACATACTGGGCCAAGCATATATTGAACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCT
GGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACATGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATG
CGACGACCTCCCCAGGGTCTACCTAATCAGCTACCTGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCT
GTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCT
GAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAA
CTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAG
GTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCA
TATACAGATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAG
TGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTT
ACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAAT
GTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCAGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTT
GAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGTGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCT
TGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGTTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCA
CCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCC
ATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCA
ACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCC
CAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTT
TTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGAT
TTTGATGCAATTACAGATCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATG
CCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCC
ATTCCTCAGGATGGCAGTATAACACATCAGATTTCTAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAG
CAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTGCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCT
AAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAGAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACT
GAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAA
CAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACC
ATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGA
ATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTA
CCAATAAAAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAAC
AATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAG
GTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTG
TCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGTGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAA
ATGGGGCAGGTTTTACAGCAGCAGAATATACAACAAGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGG
CAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAAT
CTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTC
CCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCA
GAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGAT
ATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAA
GAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGAT
TTCTCACAAGCAACTCCAAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATA
AAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCT
GTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCCCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAA
CACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTGAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAAT
AAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTGCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCA
AAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGG
AAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCA
ACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGA
AAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTG
GCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATA
CAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTAT
CCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCA
GAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGT
CTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGA
ATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTAT
CGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTA
CCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGT
TGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACC
AAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAG
GAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGAT
GTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTC
GAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTC
AATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAA
ATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAA
GGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAG
GTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACG
GGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGAC
AAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAG
CGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATT
GGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGC
ACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAA
GGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCT
GAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTT
CCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGT
GCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTT
CAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAA
TGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATT
GAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGC
ATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAA
GTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTT
GACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGC
TCAGCGGGCGGCTTGTCCCTAGGAAGAGGCGATTCAACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGA
CTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTG
AAGTGGCCGAGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGT
TTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTG
CCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAA
GGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAG
CTAAGGGATAATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGA
AACTTTTGTATTTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACT
AACAAACCCTGTTACTTTGTACAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCT
GCAGCAGCTCGGGGGCTTATAAAATGTTCATAGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACC
AAAATTTCAACCTAGAGTGTTGGGGGTTTTTTGGAAACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGG
GGCGTATGCTACGACTACAACTTTTATAGCTGTTTTGGTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGT
CAGGTTTTTTTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAA
GTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGC
CTTCTATTTAACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTT
TGGAAGATGTAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAA
ACTTAATCAGCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGT
TTTGTGTGCACAATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCT
TACAGAATAAATCAATTGTATATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATAT
CCTGACATCCTACCAGTATTTGTCCTACCGGGTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTT

>In-frame_MFN1_ENST00000471841_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_14026nt
AGTGACCGCCCTTTGCCACTCCCCCTGCCTCCTCTCCGCCTTTAACTTCTCGGGAAGATGAGGCAGTTTGGCATCTGTGGCCGAGTTGCT
GTTGCCGGGTGATAGTTGGAGCGGAGACTTAGCATAATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATT
ACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACTGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATA
GCCACTGAAGATGATCTGGTAGAAATGCAAGGATATAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTG
GCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTGTGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGC
GCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGCTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGA
TGGATGCATGCAGTTTGTCAGAACTTAAATACTGAGGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCC
TATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCA
CCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAA
CGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCA
AGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGAT
GATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGG
CAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGA
GATGATGGCTGGAGTGAGCAGTTACCAGATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATAC
CGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCTGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAA
AGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGAGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTA
GATCCACTACTTAGTTCATCCTCGGCTCCAACAAAATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTA
AACACAGATGATGACATTCTTGGAATAATTTCAGATGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCT
TCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAA
ATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTT
AGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGG
ATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCA
ATTGCACAATCCTCTTATCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCA
GCTCCCACTGTGGAAGGAGAAAATGACACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATG
GCAACTGTTGCCCCAGTTCTCTACACCAATATTAATTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATT
GCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGAGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAA
GTACAGATGTCAAATGATTCCATGAAAAGGCAGCAACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGAT
CCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAA
GCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGT
TCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAA
CTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCC
CCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAAC
TCACGACCACCATCTCCAATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAAT
TCTGCTGCACCAGTGGAAAACTGTACACCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCT
GTCAGAGATTTATGTTCTTCTTCCACGACAAATAATGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTT
CCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTTTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACT
AAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAAAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGT
GGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCT
GTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCC
CTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAG
GACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCT
TACTCTCAACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGAC
TTGTTTGTTACACCTGTAACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTAC
TCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGAT
CCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCTTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCC
CCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTTTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCT
CAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCATGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCA
AACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAG
AATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAG
AAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTT
AACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTC
CCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGT
CATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTA
TCTGTAGATATGCCTAGGCCTTTAAATAACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTT
CAGCAGCACAACATACTGGGCCAAGCATATATTGAACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCT
GGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACATGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATG
CGACGACCTCCCCAGGGTCTACCTAATCAGCTACCTGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCT
GTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCT
GAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAA
CTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAG
GTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCA
TATACAGATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAG
TGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTT
ACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAAT
GTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCAGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTT
GAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGTGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCT
TGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGTTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCA
CCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCC
ATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCA
ACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCC
CAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTT
TTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGAT
TTTGATGCAATTACAGATCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATG
CCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCC
ATTCCTCAGGATGGCAGTATAACACATCAGATTTCTAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAG
CAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTGCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCT
AAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAGAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACT
GAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAA
CAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACC
ATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGA
ATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTA
CCAATAAAAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAAC
AATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAG
GTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTG
TCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGTGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAA
ATGGGGCAGGTTTTACAGCAGCAGAATATACAACAAGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGG
CAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAAT
CTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTC
CCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCA
GAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGAT
ATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAA
GAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGAT
TTCTCACAAGCAACTCCAAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATA
AAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCT
GTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCCCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAA
CACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTGAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAAT
AAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTGCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCA
AAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGG
AAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCT
CTAATGGAACCAATCATTGGAGTGAACTTTGCGCACTTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACT
TTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTACTATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCT
GCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGA
GTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCT
CTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCAC
TGTGGTGATCGAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTG
TCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGA
AGGAATGACATCAAAACTGAGCCAGGCACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCT
GTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAAC
AGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCAT
TTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCT
CCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGT
AAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTA
GAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATT
CCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGT
CTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAG
CCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAA
TGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAA
TTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGA
TTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAG
ACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACT
AGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATG
CTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAG
GTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTG
CTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTAT
GCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAA
GACCTGGTTCTAAGTGACATCTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTC
CAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTT
GAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCT
GAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACA
GTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCC
AATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATC
GGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAAC
GACCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACT
TTTGAGAGAGGACACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAA
GATGACCAGCACAAGATTCCGTGTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGC
GGCTTGTCCCTAGGAAGAGGCGATTCAACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAA
AAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCG
AGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTT
CCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTGCCCTGCCCC
GGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAAGGGGCAGGC
CCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAGCTAAGGGAT
AATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGAAACTTTTGT
ATTTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAACCC
TGTTACTTTGTACAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCT
CGGGGGCTTATAAAATGTTCATAGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCA
ACCTAGAGTGTTGGGGGTTTTTTGGAAACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGC
TACGACTACAACTTTTATAGCTGTTTTGGTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTT
TTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTG
ATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGCCTTCTATTT
AACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTTTGGAAGATG
TAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAAACTTAATCA
GCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGTTTTGTGTGC
ACAATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAATA
AATCAATTGTATATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATC
CTACCAGTATTTGTCCTACCGGGTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATA

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000262189_chr7_151921264_-_13824nt
TTGATGAATGTCACTGGTGTGTCATCAGTTTGCATGTCTATCATCCACTTTAGTTGGTGCTTTTCTAACTTTATCTCCCTCTAGTAGCAT
AATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTAC
TGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATA
TAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTG
TGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTG
CTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGA
GGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTG
CTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGAC
TGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAA
TCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGA
ACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGT
CAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAG
ATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTT
AGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCC
TGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGG
AGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAA
ATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGA
TGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTC
ACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATA
TAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACA
GCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCC
TCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAA
AAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTC
GAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAA
TTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAG
AGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCA
ACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGA
ATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCA
GCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTT
GACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTC
TACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCA
GGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAA
AATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATC
ATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAA
TGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGT
TTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACA
AAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCC
TCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAG
ACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGC
CCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACC
TGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTAC
TGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTC
TGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTC
AGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGC
TTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGT
TTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCA
TGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTC
TGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAA
ATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGA
CTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCC
TGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGT
TGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGT
GCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACA
AATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGA
ACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACA
TGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACC
TGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAA
CCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCA
GCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAA
AGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAAC
TAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAA
AAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGA
AAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAA
TTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTC
AGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAG
TGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAG
TTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCA
TGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAA
CCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGC
AACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCA
GAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAG
ACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAA
AATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGG
CCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTC
TAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCT
GCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAA
GAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACA
GATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCAT
GATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCA
GCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGC
TCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGT
CTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACG
TAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGA
AATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTG
TGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACA
AGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACC
ATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAG
GCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACA
CAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAA
GAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAAC
TACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAA
TATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGC
AAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGG
CCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCC
CCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTT
GAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACT
GCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCG
AAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTC
TAGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCC
TATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAA
AACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGA
TGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAG
TTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGA
ACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGG
CACTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGC
TGCTGAGAACATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGA
TGTCCCATCCATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGG
ATCTGCAAACCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATA
TAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGT
GCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAA
TAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAG
AGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTC
TCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAA
GCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTG
GAGCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCT
TAAACCTGATCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACT
CAACCTTGACTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGT
GGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCAC
CAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGG
AATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCA
ACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCA
TTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTG
CTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACC
TAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGG
AGAGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCG
ATACGGCCGAAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAA
GAGGTTTGTGTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTA
TAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGAT
TCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGC
CAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCAC
AGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCAT
CAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCA
CTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGCGGCTTGTCCCTAGGAAGAGGCGATTC
AACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCT
CAGTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCGAGGTTAAACGGAATCACAGAATGGTC
CAGCACTTTTGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTT
GGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTGCCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAA
GACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAAGGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAAT
AAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAGCTAAGGGATAATAACTTGCACTAAATACATTTAAA
TACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGAAACTTTTGTATTTATTATTGAATAAGTGAATGAAG
CTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAACCCTGTTACTTTGTACAGATATGTAAATA
TTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCTCGGGGGCTTATAAAATGTTCATAGGG
ATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCAACCTAGAGTGTTGGGGGTTTTTTGGA
AACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGCTACGACTACAACTTTTATAGCTGTTT
TGGTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTTTTGTGCTTACAATTTGTGATAACTGT
GAATAACTGCTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAG
AATCATGTAAACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGCCTTCTATTTAACACAAAAATTTGAAAAAGTTAAAA
AAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTTTGGAAGATGTAATTTTAAAATGTGTTTGTATGAAC
TGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAAACTTAATCAGCATTTTGAACCAGGTTAGCTTTTTA
TTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGTTTTGTGTGCACAATTCAAGTGGACTGTAAACTGTT
GGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAATAAATCAATTGTATATATTTTTCTCTTG
ATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATCCTACCAGTATTTGTCCTACCGGGTTT
TTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATACAGAGTGTTATGGGTTTTGGAATTTG

>In-frame_MFN1_ENST00000263969_chr3_179069823_+_KMT2C_ENST00000355193_chr7_151921264_-_13991nt
TTGATGAATGTCACTGGTGTGTCATCAGTTTGCATGTCTATCATCCACTTTAGTTGGTGCTTTTCTAACTTTATCTCCCTCTAGTAGCAT
AATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTAC
TGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATA
TAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGTGTGTTTGGTGCAGACACTG
TGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTG
CTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGA
GGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTG
CTGTGAATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGAC
TGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAA
TCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGA
ACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGT
CAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAG
ATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCAGATACTTT
AGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCC
TGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGG
AGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAA
ATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGA
TGATCTAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTC
ACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATA
TAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACA
GCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCC
TCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAA
AAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGACACAATGTC
GAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAA
TTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAG
AGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCA
ACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGA
ATGGAAATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCA
GCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTT
GACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTC
TACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCA
GGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAA
AATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACACCTTTATC
ATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAA
TGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGT
TTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACA
AAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCC
TCCATCCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAG
ACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGC
CCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACC
TGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTAC
TGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTC
TGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCAAGGATTTC
AGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGC
TTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGT
TTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCA
TGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTC
TGGTGTCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAA
ATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGA
CTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCC
TGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGT
TGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGT
GCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAATAACTCACA
AATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGA
ACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACA
TGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACC
TGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAA
CCATCCACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCA
GCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAA
AGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAAC
TAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAA
AAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGA
AAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAA
TTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTC
AGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAG
TGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAG
TTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCA
TGTGTCAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAA
CCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGC
AACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCA
GAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAG
ACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAA
AATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCTTTTATGGG
CCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTC
TAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCT
GCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAA
GAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACA
GATTCGTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCAT
GATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCA
GCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGC
TCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGT
CTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACG
TAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGA
AATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTG
TGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACA
AGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACC
ATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAG
GCCTTCTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACA
CAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAA
GAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAAC
TACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAA
TATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGC
AAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGG
CCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCC
CCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTT
GAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACT
GCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCG
AAGCAAACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTC
TAGCACTGACACGTTTACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCTCTAATGGAACCAATCATTGGAGTGAACTTTGCGCA
CTTTCTTCCTTATGGCAGTGGCCAATTTAATAGTGGGAATCGACTTCTAGGAACTTTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTA
CTATTCTCAGTTGATCTACAAGCAGAATAATTTAAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTG
TCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGG
ACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGC
CTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATCGAGATACTCCTGACAGTTTTGTTCC
CTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCCTCCAGAACCGGTGCC
GTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACTTTATA
TTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAA
CATTAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATC
CATGGGTTTGGTCAGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAA
CCCTCCCAGATTAGTGAGCTCTTACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTC
TAGTCATGGTATTGCAGAAAGCGCAGCACTCAGACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATC
TTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTT
TATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATTCCTTCATTGCCACAATCACCTATGAGAGAAACGCC
TTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGCTCCCAGAGAAAGCTTCTCCCCCTGC
CTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGACAGTCAAGCTGAAGCC
TCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGCATTCA
TATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGA
TCCTGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGA
CTTGGATCTGTGGGTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGC
TCTGAGGAGAGGCCTACAAATGAAATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTA
TCACTTCACTTGCGCCATTAAAGCACAATGCATGTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGA
GCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGA
ACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAA
AGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGCGCTGCCGCTACCTGTGCTCCATTGA
GGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACATCTCACCTAAAGGTGT
CTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAGGATCT
GTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCG
AAATCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGT
GTTAAGGCCTCACACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACA
GTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCT
GGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAA
AGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCC
CGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAG
TCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGTGTCACTGTGGAGC
TGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGCGGCTTGTCCCTAGGAAGAGGCGATTCAACACACCA
TTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTT
AGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCGAGGTTAAACGGAATCACAGAATGGTCCAGCACTTT
TGCTTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTA
GTCTCACTAAGGAGAAACTTTTACTGGGGCAAAGAGCCGATGGCTGCCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAAGACTGAAAT
CACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCTTATTAAAAAGGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAATAAAGTAGAC
ACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAGCTAAGGGATAATAACTTGCACTAAATACATTTAAATACTTGATT
CCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGAAACTTTTGTATTTATTATTGAATAAGTGAATGAAGCTATTTTTA
AATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAACCCTGTTACTTTGTACAGATATGTAAATATTTTGAGAA
AAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCTCGGGGGCTTATAAAATGTTCATAGGGATGTTACAA
TATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCAACCTAGAGTGTTGGGGGTTTTTTGGAAACCGCAGT
CTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGCTACGACTACAACTTTTATAGCTGTTTTGGTAATTT
AAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTTTTGTGCTTACAATTTGTGATAACTGTGAATAACTG
CTTAAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAGAATCATGTA
AACGTAATAGGATCATGTAGCAGAAACTTAAATCTAACCCTTTAGCCTTCTATTTAACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGG
AGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAATAGGGTTTTTGGAAGATGTAATTTTAAAATGTGTTTGTATGAACTGTTTGTTT
ACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAAACTTAATCAGCATTTTGAACCAGGTTAGCTTTTTATTTTGTACT
TAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGTTTTGTGTGCACAATTCAAGTGGACTGTAAACTGTTGGTATATTC
AGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAATAAATCAATTGTATATATTTTTCTCTTGATAAATAGC
TGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATCCTACCAGTATTTGTCCTACCGGGTTTTTGTTGTTT
TCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATACAGAGTGTTATGGGTTTTGGAATTTGTGGACACAG


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FusionGenePPI for MFN1_KMT2C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MFN1MARCH5, PARK2, ILF2, CCNB1, MAVS, FAF2, NTRK1, PLK2, SLC25A38, MFN2, TOMM22, FLNC, MGRN1, MFN1KMT2CAK1, NCOA6, ASH2L, RBBP5, HIST2H3C, ASCL2, KDM6A, SMARCB1, MAPK14, JUN, PAXIP1, H3F3A, PAGR1, WDR82, CDC73, TSC22D1, KDM4B, ELAVL1, WDR5, HIST1H3A, APPL2, ERP44, HIST3H3, DPY30, MTNR1B, FOXA1, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MFN1_KMT2C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MFN1_KMT2C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMFN1C2931673Ceroid lipofuscinosis, neuronal 1, infantile1CTD_human
TgeneKMT2CC0001418Adenocarcinoma1CTD_human
TgeneKMT2CC0005695Bladder Neoplasm1CTD_human
TgeneKMT2CC0007138Carcinoma, Transitional Cell1CTD_human
TgeneKMT2CC0010606Adenoid Cystic Carcinoma1CTD_human
TgeneKMT2CC0023467Leukemia, Myelocytic, Acute1CTD_human
TgeneKMT2CC0023897Liver Diseases, Parasitic1CTD_human
TgeneKMT2CC0036920Sezary Syndrome1CTD_human
TgeneKMT2CC0038356Stomach Neoplasms1CTD_human
TgeneKMT2CC0206698Cholangiocarcinoma1CTD_human
TgeneKMT2CC0279626Squamous cell carcinoma of esophagus1CTD_human
TgeneKMT2CC2239176Liver carcinoma1CTD_human