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Fusion gene ID: 21741 |
FusionGeneSummary for MFAP1_STRC |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MFAP1_STRC | Fusion gene ID: 21741 | Hgene | Tgene | Gene symbol | MFAP1 | STRC | Gene ID | 4236 | 161497 |
| Gene name | microfibril associated protein 1 | stereocilin | |
| Synonyms | AMP | DFNB16 | |
| Cytomap | 15q15.3 | 15q15.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | microfibrillar-associated protein 1microfibrillar associated protein 1 | stereocilin | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | P55081 | Q7RTU9 | |
| Ensembl transtripts involved in fusion gene | ENST00000267812, | ENST00000450892, ENST00000541030, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 2 X 1 X 2=4 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: MFAP1 [Title/Abstract] AND STRC [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-EJ-5516-01A | MFAP1 | chr15 | 44105185 | - | STRC | chr15 | 43897597 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000267812 | ENST00000450892 | MFAP1 | chr15 | 44105185 | - | STRC | chr15 | 43897597 | - |
| In-frame | ENST00000267812 | ENST00000541030 | MFAP1 | chr15 | 44105185 | - | STRC | chr15 | 43897597 | - |
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FusionProtFeatures for MFAP1_STRC |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MFAP1 | STRC |
| May be required for pre-mRNA splicing.{ECO:0000250|UniProtKB:Q9W062}. | Essential to the formation of horizontal top connectorsbetween outer hair cell stereocilia. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MFAP1 | chr15:44105185 | chr15:43897597 | ENST00000267812 | - | 6 | 9 | 51_318 | 295 | 440 | Compositional bias | Glu-rich |
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FusionGeneSequence for MFAP1_STRC |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000450892_chr15_43897597_-_807aa MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQ NRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESE SESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDE NDEEEYEAWKVRELKRIKRDREDREAIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGEVLETLGPLV GFLGTESTRQIPLQILLSHLSQLQGFCLGETFATELGWLLLQESVLGKPELWSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLE KQQSWEQSRVGQLCREPQLAAKKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAAWSATQIAEMELSDFEDCLTLFAGDPGLGPEELRAA MGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTLGQIDGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLC GLRPEELQHISSWEFSQAALFLGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQIQGVTPLAIS >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000541030_chr15_43897597_-_807aa MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQ NRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESE SESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDE NDEEEYEAWKVRELKRIKRDREDREAIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGEVLETLGPLV GFLGTESTRQIPLQILLSHLSQLQGFCLGETFATELGWLLLQESVLGKPELWSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLE KQQSWEQSRVGQLCREPQLAAKKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAAWSATQIAEMELSDFEDCLTLFAGDPGLGPEELRAA MGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTLGQIDGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLC GLRPEELQHISSWEFSQAALFLGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQIQGVTPLAIS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000450892_chr15_43897597_-_2421nt ATGTCGGTCCCAAGCGCTCTCATGAAGCAACCGCCCATTCAGTCTACGGCTGGGGCCGTCCCAGTTCGCAATGAGAAAGGTGAGATTTCA ATGGAAAAAGTGAAGGTAAAGCGTTATGTGTCCGGAAAAAGGCCAGACTATGCCCCTATGGAGTCCTCAGATGAGGAGGATGAAGAATTT CAGTTCATTAAGAAAGCCAAAGAACAAGAAGCAGAGCCTGAGGAACAGGAGGAGGATTCATCCAGTGACCCCCGGCTACGGCGTTTACAG AACCGTATTAGTGAAGATGTGGAAGAGAGATTGGCTCGACATCGAAAAATAGTGGAACCTGAAGTGGTAGGAGAGAGTGACTCAGAAGTA GAAGGAGATGCTTGGCGCATGGAACGAGAAGACAGCAGTGAAGAAGAGGAGGAGGAAATTGATGATGAGGAAATAGAGCGGCGGCGTGGC ATGATGCGTCAGCGAGCACAGGAGAGAAAAAATGAAGAGATGGAAGTCATGGAAGTGGAAGATGAGGGTCGTTCTGGAGAGGAGTCAGAA TCAGAGTCTGAGTATGAAGAGTACACAGACAGTGAAGATGAGATGGAGCCTCGCCTTAAGCCAGTCTTCATTCGAAAGAAGGACCGAGTG ACAGTTCAAGAACGTGAAGCCGAAGCATTGAAACAGAAGGAGCTGGAGCAGGAAGCAAAACGCATGGCTGAGGAAAGGCGCAAGTACACA CTCAAGATTGTCGAAGAGGAAACCAAAAAAGAGCTGGAAGAGAACAAGCGATCCCTGGCTGCATTGGATGCACTCAATACTGATGATGAA AATGATGAGGAGGAATATGAGGCATGGAAAGTTCGAGAGCTAAAAAGAATCAAGAGGGACAGAGAAGATCGAGAAGCGATCCAGTTGATG GACAGACTATCCAATGAATCCATTATGTTGGTGGTGGAGCTGGTGCAAAGAGCTCCAGAGCAGCTGCTGGCACTGACCCCCCTCCACCAG GCAGCCCTGGCAGAGAGGGCACTACAAAACCTGGCTCCAAAGGAGACTCCAGTCTCAGGGGAAGTGCTGGAGACCTTAGGCCCTTTGGTT GGATTCCTGGGGACAGAGAGCACACGACAGATCCCCCTACAGATCCTGCTGTCCCATCTCAGTCAGCTGCAAGGCTTCTGCCTAGGAGAG ACATTTGCCACAGAGCTGGGATGGCTGCTATTGCAGGAGTCTGTTCTTGGGAAACCAGAGTTGTGGAGCCAGGATGAAGTAGAGCAAGCT GGACGCCTAGTATTCACTCTGTCTACTGAGGCAATTTCCTTGATCCCCAGGGAGGCCTTGGGTCCAGAGACCCTGGAGCGGCTTCTAGAA AAGCAGCAGAGCTGGGAGCAGAGCAGAGTTGGACAGCTGTGTAGGGAGCCACAGCTTGCTGCCAAGAAAGCAGCCCTGGTAGCAGGGGTG GTGCGACCAGCTGCTGAGGATCTTCCAGAACCTGTGCCAAATTGTGCAGATGTACGAGGGACATTCCCAGCAGCCTGGTCTGCAACCCAG ATTGCAGAGATGGAGCTCTCAGACTTTGAGGACTGCCTGACATTATTTGCAGGAGACCCAGGACTTGGGCCTGAGGAACTGCGGGCAGCC ATGGGCAAAGCAAAACAGTTGTGGGGTCCCCCCCGGGGATTTCGTCCTGAGCAGATCCTGCAGCTTGGTAGGCTCTTAATAGGTCTAGGA GATCGGGAACTACAGGAGCTGATCCTAGTGGACTGGGGAGTGCTGAGCACCCTGGGGCAGATAGATGGCTGGAGCACCACTCAGCTCCGC ATTGTGGTCTCCAGTTTCCTACGGCAGAGTGGTCGGCATGTGAGCCACCTGGACTTCGTTCATCTGACAGCGCTGGGTTATACTCTCTGT GGACTGCGGCCAGAGGAGCTCCAGCACATCAGCAGTTGGGAGTTCAGCCAAGCAGCTCTCTTCCTCGGCACCCTGCATCTCCAGTGCTCT GAGGAACAACTGGAGGTTCTGGCCCACCTACTTGTACTGCCTGGTGGGTTTGGCCCAATCAGTAACTGGGGGCCTGAGATCTTCACTGAA ATTGGCACCATAGCAGCTGGGATCCCAGACCTGGCTCTTTCAGCACTGCTGCGGGGACAGATCCAGGGCGTTACTCCTCTTGCCATTTCT GTCATCCCTCCTCCTAAATTTGCTGTGGTGTTTAGTCCCATCCAACTATCTAGTCTCACCAGTGCTCAGGCTGTGGCTGTCACTCCTGAG CAAATGGCCTTTCTGAGTCCTGAGCAGCGACGAGCAGTTGCATGGGCCCAACATGAGGGAAAGGAGAGCCCAGAACAGCAAGGTCGAAGT >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000541030_chr15_43897597_-_2421nt ATGTCGGTCCCAAGCGCTCTCATGAAGCAACCGCCCATTCAGTCTACGGCTGGGGCCGTCCCAGTTCGCAATGAGAAAGGTGAGATTTCA ATGGAAAAAGTGAAGGTAAAGCGTTATGTGTCCGGAAAAAGGCCAGACTATGCCCCTATGGAGTCCTCAGATGAGGAGGATGAAGAATTT CAGTTCATTAAGAAAGCCAAAGAACAAGAAGCAGAGCCTGAGGAACAGGAGGAGGATTCATCCAGTGACCCCCGGCTACGGCGTTTACAG AACCGTATTAGTGAAGATGTGGAAGAGAGATTGGCTCGACATCGAAAAATAGTGGAACCTGAAGTGGTAGGAGAGAGTGACTCAGAAGTA GAAGGAGATGCTTGGCGCATGGAACGAGAAGACAGCAGTGAAGAAGAGGAGGAGGAAATTGATGATGAGGAAATAGAGCGGCGGCGTGGC ATGATGCGTCAGCGAGCACAGGAGAGAAAAAATGAAGAGATGGAAGTCATGGAAGTGGAAGATGAGGGTCGTTCTGGAGAGGAGTCAGAA TCAGAGTCTGAGTATGAAGAGTACACAGACAGTGAAGATGAGATGGAGCCTCGCCTTAAGCCAGTCTTCATTCGAAAGAAGGACCGAGTG ACAGTTCAAGAACGTGAAGCCGAAGCATTGAAACAGAAGGAGCTGGAGCAGGAAGCAAAACGCATGGCTGAGGAAAGGCGCAAGTACACA CTCAAGATTGTCGAAGAGGAAACCAAAAAAGAGCTGGAAGAGAACAAGCGATCCCTGGCTGCATTGGATGCACTCAATACTGATGATGAA AATGATGAGGAGGAATATGAGGCATGGAAAGTTCGAGAGCTAAAAAGAATCAAGAGGGACAGAGAAGATCGAGAAGCGATCCAGTTGATG GACAGACTATCCAATGAATCCATTATGTTGGTGGTGGAGCTGGTGCAAAGAGCTCCAGAGCAGCTGCTGGCACTGACCCCCCTCCACCAG GCAGCCCTGGCAGAGAGGGCACTACAAAACCTGGCTCCAAAGGAGACTCCAGTCTCAGGGGAAGTGCTGGAGACCTTAGGCCCTTTGGTT GGATTCCTGGGGACAGAGAGCACACGACAGATCCCCCTACAGATCCTGCTGTCCCATCTCAGTCAGCTGCAAGGCTTCTGCCTAGGAGAG ACATTTGCCACAGAGCTGGGATGGCTGCTATTGCAGGAGTCTGTTCTTGGGAAACCAGAGTTGTGGAGCCAGGATGAAGTAGAGCAAGCT GGACGCCTAGTATTCACTCTGTCTACTGAGGCAATTTCCTTGATCCCCAGGGAGGCCTTGGGTCCAGAGACCCTGGAGCGGCTTCTAGAA AAGCAGCAGAGCTGGGAGCAGAGCAGAGTTGGACAGCTGTGTAGGGAGCCACAGCTTGCTGCCAAGAAAGCAGCCCTGGTAGCAGGGGTG GTGCGACCAGCTGCTGAGGATCTTCCAGAACCTGTGCCAAATTGTGCAGATGTACGAGGGACATTCCCAGCAGCCTGGTCTGCAACCCAG ATTGCAGAGATGGAGCTCTCAGACTTTGAGGACTGCCTGACATTATTTGCAGGAGACCCAGGACTTGGGCCTGAGGAACTGCGGGCAGCC ATGGGCAAAGCAAAACAGTTGTGGGGTCCCCCCCGGGGATTTCGTCCTGAGCAGATCCTGCAGCTTGGTAGGCTCTTAATAGGTCTAGGA GATCGGGAACTACAGGAGCTGATCCTAGTGGACTGGGGAGTGCTGAGCACCCTGGGGCAGATAGATGGCTGGAGCACCACTCAGCTCCGC ATTGTGGTCTCCAGTTTCCTACGGCAGAGTGGTCGGCATGTGAGCCACCTGGACTTCGTTCATCTGACAGCGCTGGGTTATACTCTCTGT GGACTGCGGCCAGAGGAGCTCCAGCACATCAGCAGTTGGGAGTTCAGCCAAGCAGCTCTCTTCCTCGGCACCCTGCATCTCCAGTGCTCT GAGGAACAACTGGAGGTTCTGGCCCACCTACTTGTACTGCCTGGTGGGTTTGGCCCAATCAGTAACTGGGGGCCTGAGATCTTCACTGAA ATTGGCACCATAGCAGCTGGGATCCCAGACCTGGCTCTTTCAGCACTGCTGCGGGGACAGATCCAGGGCGTTACTCCTCTTGCCATTTCT GTCATCCCTCCTCCTAAATTTGCTGTGGTGTTTAGTCCCATCCAACTATCTAGTCTCACCAGTGCTCAGGCTGTGGCTGTCACTCCTGAG CAAATGGCCTTTCTGAGTCCTGAGCAGCGACGAGCAGTTGCATGGGCCCAACATGAGGGAAAGGAGAGCCCAGAACAGCAAGGTCGAAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000450892_chr15_43897597_-_2928nt GCAGAAACCGACTCGACTTCCTAGCTGTGGGCGCCCAAACGTCGTCCACCATCCCACAATCCTCTCGTCACGTATTTCCGGTTTATCTAG CTCAGCCGTAAGTAGTTTCTCTATCAGTCGCGCAGCTGTGTTCGCGGACTCAGGTGGAAGGAATTTCTTCTCTTCGTTGACGTTGCTGGT GTTCACTGTTTGGAATTAGTCAAGTTTCGGGAATCACCGTCGCTGCCATCAACATGTCGGTCCCAAGCGCTCTCATGAAGCAACCGCCCA TTCAGTCTACGGCTGGGGCCGTCCCAGTTCGCAATGAGAAAGGTGAGATTTCAATGGAAAAAGTGAAGGTAAAGCGTTATGTGTCCGGAA AAAGGCCAGACTATGCCCCTATGGAGTCCTCAGATGAGGAGGATGAAGAATTTCAGTTCATTAAGAAAGCCAAAGAACAAGAAGCAGAGC CTGAGGAACAGGAGGAGGATTCATCCAGTGACCCCCGGCTACGGCGTTTACAGAACCGTATTAGTGAAGATGTGGAAGAGAGATTGGCTC GACATCGAAAAATAGTGGAACCTGAAGTGGTAGGAGAGAGTGACTCAGAAGTAGAAGGAGATGCTTGGCGCATGGAACGAGAAGACAGCA GTGAAGAAGAGGAGGAGGAAATTGATGATGAGGAAATAGAGCGGCGGCGTGGCATGATGCGTCAGCGAGCACAGGAGAGAAAAAATGAAG AGATGGAAGTCATGGAAGTGGAAGATGAGGGTCGTTCTGGAGAGGAGTCAGAATCAGAGTCTGAGTATGAAGAGTACACAGACAGTGAAG ATGAGATGGAGCCTCGCCTTAAGCCAGTCTTCATTCGAAAGAAGGACCGAGTGACAGTTCAAGAACGTGAAGCCGAAGCATTGAAACAGA AGGAGCTGGAGCAGGAAGCAAAACGCATGGCTGAGGAAAGGCGCAAGTACACACTCAAGATTGTCGAAGAGGAAACCAAAAAAGAGCTGG AAGAGAACAAGCGATCCCTGGCTGCATTGGATGCACTCAATACTGATGATGAAAATGATGAGGAGGAATATGAGGCATGGAAAGTTCGAG AGCTAAAAAGAATCAAGAGGGACAGAGAAGATCGAGAAGCGATCCAGTTGATGGACAGACTATCCAATGAATCCATTATGTTGGTGGTGG AGCTGGTGCAAAGAGCTCCAGAGCAGCTGCTGGCACTGACCCCCCTCCACCAGGCAGCCCTGGCAGAGAGGGCACTACAAAACCTGGCTC CAAAGGAGACTCCAGTCTCAGGGGAAGTGCTGGAGACCTTAGGCCCTTTGGTTGGATTCCTGGGGACAGAGAGCACACGACAGATCCCCC TACAGATCCTGCTGTCCCATCTCAGTCAGCTGCAAGGCTTCTGCCTAGGAGAGACATTTGCCACAGAGCTGGGATGGCTGCTATTGCAGG AGTCTGTTCTTGGGAAACCAGAGTTGTGGAGCCAGGATGAAGTAGAGCAAGCTGGACGCCTAGTATTCACTCTGTCTACTGAGGCAATTT CCTTGATCCCCAGGGAGGCCTTGGGTCCAGAGACCCTGGAGCGGCTTCTAGAAAAGCAGCAGAGCTGGGAGCAGAGCAGAGTTGGACAGC TGTGTAGGGAGCCACAGCTTGCTGCCAAGAAAGCAGCCCTGGTAGCAGGGGTGGTGCGACCAGCTGCTGAGGATCTTCCAGAACCTGTGC CAAATTGTGCAGATGTACGAGGGACATTCCCAGCAGCCTGGTCTGCAACCCAGATTGCAGAGATGGAGCTCTCAGACTTTGAGGACTGCC TGACATTATTTGCAGGAGACCCAGGACTTGGGCCTGAGGAACTGCGGGCAGCCATGGGCAAAGCAAAACAGTTGTGGGGTCCCCCCCGGG GATTTCGTCCTGAGCAGATCCTGCAGCTTGGTAGGCTCTTAATAGGTCTAGGAGATCGGGAACTACAGGAGCTGATCCTAGTGGACTGGG GAGTGCTGAGCACCCTGGGGCAGATAGATGGCTGGAGCACCACTCAGCTCCGCATTGTGGTCTCCAGTTTCCTACGGCAGAGTGGTCGGC ATGTGAGCCACCTGGACTTCGTTCATCTGACAGCGCTGGGTTATACTCTCTGTGGACTGCGGCCAGAGGAGCTCCAGCACATCAGCAGTT GGGAGTTCAGCCAAGCAGCTCTCTTCCTCGGCACCCTGCATCTCCAGTGCTCTGAGGAACAACTGGAGGTTCTGGCCCACCTACTTGTAC TGCCTGGTGGGTTTGGCCCAATCAGTAACTGGGGGCCTGAGATCTTCACTGAAATTGGCACCATAGCAGCTGGGATCCCAGACCTGGCTC TTTCAGCACTGCTGCGGGGACAGATCCAGGGCGTTACTCCTCTTGCCATTTCTGTCATCCCTCCTCCTAAATTTGCTGTGGTGTTTAGTC CCATCCAACTATCTAGTCTCACCAGTGCTCAGGCTGTGGCTGTCACTCCTGAGCAAATGGCCTTTCTGAGTCCTGAGCAGCGACGAGCAG TTGCATGGGCCCAACATGAGGGAAAGGAGAGCCCAGAACAGCAAGGTCGAAGTACAGCCTGGGGCCTCCAGGACTGGTCACGACCTTCCT GGTCCCTGGTATTGACTATCAGCTTCCTTGGCCACCTGCTATGAGCCTGTCTCTACAGTAGAAGGAGATTGTGGGGAGAGAAATCTTAAG TCATAATGAATAAAGTGCAAACAGAAGTGCATCCTGATTATTTTCAGAAGCTGATGAGGAATATGGGTAAAATGTTAATGCTTTCCACCC ACCTGAGAATCAGTGTTCCTGGGTTGCCATATCTGGAGTCTCTTTCCATCATAAATAATCCCACTGCCTCTTTTCATTTCCTGAAGGCTG >In-frame_MFAP1_ENST00000267812_chr15_44105185_-_STRC_ENST00000541030_chr15_43897597_-_2693nt GCAGAAACCGACTCGACTTCCTAGCTGTGGGCGCCCAAACGTCGTCCACCATCCCACAATCCTCTCGTCACGTATTTCCGGTTTATCTAG CTCAGCCGTAAGTAGTTTCTCTATCAGTCGCGCAGCTGTGTTCGCGGACTCAGGTGGAAGGAATTTCTTCTCTTCGTTGACGTTGCTGGT GTTCACTGTTTGGAATTAGTCAAGTTTCGGGAATCACCGTCGCTGCCATCAACATGTCGGTCCCAAGCGCTCTCATGAAGCAACCGCCCA TTCAGTCTACGGCTGGGGCCGTCCCAGTTCGCAATGAGAAAGGTGAGATTTCAATGGAAAAAGTGAAGGTAAAGCGTTATGTGTCCGGAA AAAGGCCAGACTATGCCCCTATGGAGTCCTCAGATGAGGAGGATGAAGAATTTCAGTTCATTAAGAAAGCCAAAGAACAAGAAGCAGAGC CTGAGGAACAGGAGGAGGATTCATCCAGTGACCCCCGGCTACGGCGTTTACAGAACCGTATTAGTGAAGATGTGGAAGAGAGATTGGCTC GACATCGAAAAATAGTGGAACCTGAAGTGGTAGGAGAGAGTGACTCAGAAGTAGAAGGAGATGCTTGGCGCATGGAACGAGAAGACAGCA GTGAAGAAGAGGAGGAGGAAATTGATGATGAGGAAATAGAGCGGCGGCGTGGCATGATGCGTCAGCGAGCACAGGAGAGAAAAAATGAAG AGATGGAAGTCATGGAAGTGGAAGATGAGGGTCGTTCTGGAGAGGAGTCAGAATCAGAGTCTGAGTATGAAGAGTACACAGACAGTGAAG ATGAGATGGAGCCTCGCCTTAAGCCAGTCTTCATTCGAAAGAAGGACCGAGTGACAGTTCAAGAACGTGAAGCCGAAGCATTGAAACAGA AGGAGCTGGAGCAGGAAGCAAAACGCATGGCTGAGGAAAGGCGCAAGTACACACTCAAGATTGTCGAAGAGGAAACCAAAAAAGAGCTGG AAGAGAACAAGCGATCCCTGGCTGCATTGGATGCACTCAATACTGATGATGAAAATGATGAGGAGGAATATGAGGCATGGAAAGTTCGAG AGCTAAAAAGAATCAAGAGGGACAGAGAAGATCGAGAAGCGATCCAGTTGATGGACAGACTATCCAATGAATCCATTATGTTGGTGGTGG AGCTGGTGCAAAGAGCTCCAGAGCAGCTGCTGGCACTGACCCCCCTCCACCAGGCAGCCCTGGCAGAGAGGGCACTACAAAACCTGGCTC CAAAGGAGACTCCAGTCTCAGGGGAAGTGCTGGAGACCTTAGGCCCTTTGGTTGGATTCCTGGGGACAGAGAGCACACGACAGATCCCCC TACAGATCCTGCTGTCCCATCTCAGTCAGCTGCAAGGCTTCTGCCTAGGAGAGACATTTGCCACAGAGCTGGGATGGCTGCTATTGCAGG AGTCTGTTCTTGGGAAACCAGAGTTGTGGAGCCAGGATGAAGTAGAGCAAGCTGGACGCCTAGTATTCACTCTGTCTACTGAGGCAATTT CCTTGATCCCCAGGGAGGCCTTGGGTCCAGAGACCCTGGAGCGGCTTCTAGAAAAGCAGCAGAGCTGGGAGCAGAGCAGAGTTGGACAGC TGTGTAGGGAGCCACAGCTTGCTGCCAAGAAAGCAGCCCTGGTAGCAGGGGTGGTGCGACCAGCTGCTGAGGATCTTCCAGAACCTGTGC CAAATTGTGCAGATGTACGAGGGACATTCCCAGCAGCCTGGTCTGCAACCCAGATTGCAGAGATGGAGCTCTCAGACTTTGAGGACTGCC TGACATTATTTGCAGGAGACCCAGGACTTGGGCCTGAGGAACTGCGGGCAGCCATGGGCAAAGCAAAACAGTTGTGGGGTCCCCCCCGGG GATTTCGTCCTGAGCAGATCCTGCAGCTTGGTAGGCTCTTAATAGGTCTAGGAGATCGGGAACTACAGGAGCTGATCCTAGTGGACTGGG GAGTGCTGAGCACCCTGGGGCAGATAGATGGCTGGAGCACCACTCAGCTCCGCATTGTGGTCTCCAGTTTCCTACGGCAGAGTGGTCGGC ATGTGAGCCACCTGGACTTCGTTCATCTGACAGCGCTGGGTTATACTCTCTGTGGACTGCGGCCAGAGGAGCTCCAGCACATCAGCAGTT GGGAGTTCAGCCAAGCAGCTCTCTTCCTCGGCACCCTGCATCTCCAGTGCTCTGAGGAACAACTGGAGGTTCTGGCCCACCTACTTGTAC TGCCTGGTGGGTTTGGCCCAATCAGTAACTGGGGGCCTGAGATCTTCACTGAAATTGGCACCATAGCAGCTGGGATCCCAGACCTGGCTC TTTCAGCACTGCTGCGGGGACAGATCCAGGGCGTTACTCCTCTTGCCATTTCTGTCATCCCTCCTCCTAAATTTGCTGTGGTGTTTAGTC CCATCCAACTATCTAGTCTCACCAGTGCTCAGGCTGTGGCTGTCACTCCTGAGCAAATGGCCTTTCTGAGTCCTGAGCAGCGACGAGCAG TTGCATGGGCCCAACATGAGGGAAAGGAGAGCCCAGAACAGCAAGGTCGAAGTACAGCCTGGGGCCTCCAGGACTGGTCACGACCTTCCT |
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FusionGenePPI for MFAP1_STRC |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MFAP1 | YWHAG, JMJD6, CDK2, U2SURP, RPL37, PRPF40B, BARD1, U2AF1, PRPF3, SART1, SNW1, SNIP1, IK, SMU1, HSPB1, DHX8, DHX38, FRA10AC1, CSNK2A1, SOX2, AES, PHC2, GOLGA2, KIFC3, VPS52, TADA2A, ZBTB14, COIL, MAD1L1, STX11, FXR2, NDC80, MID2, MTUS2, LDOC1, AMOTL2, CEP55, CDCA7L, ZFP64, TRIM54, ZNF398, CARD9, HMBOX1, KATNBL1, GKAP1, CEP70, SSX2IP, KRT40, MIPOL1, FAM9B, BEND7, CCDC57, CEP57L1, TRIM42, ZBTB8A, OBSL1, SUZ12, RNF2, SLC25A41, PRPF38A, NTRK1, EWSR1, XPO1, MMGT1, EGFR, AP3B1, EAF1, DDX20, POLD1, NAF1, RBM14, NOLC1, EIF2AK1, ATRX, CD2BP2, TSSC4, G3BP1, LMNA | STRC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MFAP1_STRC |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MFAP1_STRC |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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