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Fusion gene ID: 21662 |
FusionGeneSummary for METAP2_VEZT |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: METAP2_VEZT | Fusion gene ID: 21662 | Hgene | Tgene | Gene symbol | METAP2 | VEZT | Gene ID | 10988 | 55591 |
| Gene name | methionyl aminopeptidase 2 | vezatin, adherens junctions transmembrane protein | |
| Synonyms | MAP2|MNPEP|p67eIF2 | VEZATIN | |
| Cytomap | 12q22 | 12q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | methionine aminopeptidase 2eIF-2-associated p67 homologinitiation factor 2-associated 67 kDa glycoproteinpeptidase M 2testicular tissue protein Li 17 | vezatin | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | P50579 | Q9HBM0 | |
| Ensembl transtripts involved in fusion gene | ENST00000323666, ENST00000546753, ENST00000261220, ENST00000550777, ENST00000551840, | ENST00000436874, ENST00000261219, ENST00000356859, | |
| Fusion gene scores | * DoF score | 2 X 3 X 3=18 | 5 X 5 X 5=125 |
| # samples | 5 | 7 | |
| ** MAII score | log2(5/18*10)=1.47393118833241 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/125*10)=-0.836501267717121 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: METAP2 [Title/Abstract] AND VEZT [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | METAP2 | GO:0016485 | protein processing | 8858118 |
| Hgene | METAP2 | GO:0018206 | peptidyl-methionine modification | 8858118 |
| Hgene | METAP2 | GO:0031365 | N-terminal protein amino acid modification | 8858118 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A7-A13D-01B | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| TCGA | LD | BRCA | TCGA-A7-A13D-01A | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| TCGA | RV | LIHC | TCGA-G3-AAUZ-01A | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000323666 | ENST00000436874 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000323666 | ENST00000261219 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| 5CDS-3UTR | ENST00000323666 | ENST00000356859 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000546753 | ENST00000436874 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000546753 | ENST00000261219 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| 5CDS-3UTR | ENST00000546753 | ENST00000356859 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000261220 | ENST00000436874 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000261220 | ENST00000261219 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| 5CDS-3UTR | ENST00000261220 | ENST00000356859 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000550777 | ENST00000436874 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000550777 | ENST00000261219 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| 5CDS-3UTR | ENST00000550777 | ENST00000356859 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000551840 | ENST00000436874 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| Frame-shift | ENST00000551840 | ENST00000261219 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| 5CDS-3UTR | ENST00000551840 | ENST00000356859 | METAP2 | chr12 | 95868106 | + | VEZT | chr12 | 95663827 | + |
| In-frame | ENST00000323666 | ENST00000436874 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000323666 | ENST00000261219 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| 5CDS-3UTR | ENST00000323666 | ENST00000356859 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000546753 | ENST00000436874 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000546753 | ENST00000261219 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| 5CDS-3UTR | ENST00000546753 | ENST00000356859 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000261220 | ENST00000436874 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000261220 | ENST00000261219 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| 5CDS-3UTR | ENST00000261220 | ENST00000356859 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000550777 | ENST00000436874 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000550777 | ENST00000261219 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| 5CDS-3UTR | ENST00000550777 | ENST00000356859 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000551840 | ENST00000436874 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| In-frame | ENST00000551840 | ENST00000261219 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
| 5CDS-3UTR | ENST00000551840 | ENST00000356859 | METAP2 | chr12 | 95889874 | + | VEZT | chr12 | 95689827 | + |
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FusionProtFeatures for METAP2_VEZT |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| METAP2 | VEZT |
| Cotranslationally removes the N-terminal methionine fromnascent proteins. The N-terminal methionine is often cleaved whenthe second residue in the primary sequence is small and uncharged(Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalyticactivity of human METAP2 toward Met-Val peptides is consistentlytwo orders of magnitude higher than that of METAP1, suggestingthat it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 fromtranslation-inhibiting phosphorylation by inhibitory kinases suchas EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in theregulation of protein synthesis. | Plays a pivotal role in the establishment of adherensjunctions and their maintenance in adult life. In case of Listeriainfection, promotes bacterial internalization by participating inmyosin VIIa recruitment to the entry site.{ECO:0000269|PubMed:15090598}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | METAP2 | chr12:95889874 | chr12:95689827 | ENST00000323666 | + | 7 | 11 | 41_46 | 289 | 479 | Compositional bias | Note=Poly-Lys |
| Hgene | METAP2 | chr12:95889874 | chr12:95689827 | ENST00000323666 | + | 7 | 11 | 98_106 | 289 | 479 | Compositional bias | Note=Poly-Lys |
| Tgene | >VEZT | chr12:95889874 | chr12:95689827 | ENST00000436874 | + | 9 | 12 | 763_766 | 541 | 780 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | VEZT | chr12:95889874 | chr12:95689827 | ENST00000436874 | + | 9 | 12 | 430_462 | 541 | 780 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | VEZT | chr12:95889874 | chr12:95689827 | ENST00000436874 | + | 9 | 12 | 139_159 | 541 | 780 | Transmembrane | Helical |
| Tgene | VEZT | chr12:95889874 | chr12:95689827 | ENST00000436874 | + | 9 | 12 | 162_182 | 541 | 780 | Transmembrane | Helical |
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FusionGeneSequence for METAP2_VEZT |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_528aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDG DGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFN PKYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAV LKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQA >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_528aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDG DGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFN PKYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAV LKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQA >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_505aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDG DGDGATGKKKKKKKKKRGRQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDC SRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEA YVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSD MGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQR >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_505aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDG DGDGATGKKKKKKKKKRGRQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDC SRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEA YVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSD MGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQR >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_505aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEAKVQT DPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDC SRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEA YVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSD MGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQR >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_505aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEAKVQT DPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDC SRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEA YVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSD MGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQR >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_492aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSADGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPN GVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAG LAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRK DDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEES NKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQRLARLQLSPDFTFT >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_492aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSADGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPN GVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAG LAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRK DDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVLKSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEES NKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQADGSGLTTAPPTPRDSLQPSIKQRLARLQLSPDFTFT >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_527aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGD GDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRK YVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNP KYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVL KSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQAD >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_527aa MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGD GDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRK YVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNP KYDTLLKAVKDATNTGIKELEAYVDDIDIDSDFRKDDFYYLSQEDKERQKREHEESKRVLQELKSVLGFKASEAERQKWKQLLFSDHAVL KSLSPVDPVEPISNSEPSMNSDMGKVSKNDTEEESNKSATTDNEISRTEYLCENSLEGKNKDNSSNEVFPQGAEERMCYQCESEDEPQAD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_1584nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCA GGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGC GATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATA TGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACT ACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGA AAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAG AATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACA GTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAAT CCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATT GATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTG CTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTG TTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAAT GATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAA AATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCA GATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCA CCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGT >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1584nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCA GGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGC GATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATA TGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACT ACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGA AAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAG AATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACA GTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAAT CCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATT GATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTG CTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTG TTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAAT GATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAA AATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCA GATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCA CCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGT >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_1515nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCA GGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGC GATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACGACAAGAATGCGAATACCCACCCACACAAGATGGG CGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCA GAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGT TCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACT CCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGT GCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCT TATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAG CATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTT CTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGAT ATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGT GAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAG AGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGG CTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATG >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1515nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCA GGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGC GATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACGACAAGAATGCGAATACCCACCCACACAAGATGGG CGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCA GAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGT TCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACT CCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGT GCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCT TATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAG CATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTT CTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGAT ATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGT GAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAG AGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGG CTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATG >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_1515nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAACCTGATAAAGAATCAGGA GCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGCAAAAGTTCAAACA GACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGG CGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCA GAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGT TCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACT CCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGT GCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCT TATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAG CATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTT CTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGAT ATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGT GAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAG AGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGG CTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATG >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1515nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAACCTGATAAAGAATCAGGA GCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGCAAAAGTTCAAACA GACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGG CGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCA GAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGT TCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACT CCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGT GCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCT TATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAG CATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTT CTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGAT ATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGT GAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAG AGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGG CTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATG >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_1476nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGATGGAGATGGCGATGGAGATGGAGCAACT GGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAAT GGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAA GCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGG ATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGC CTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGAC ATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTA TTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAG GATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCT GTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCT GTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGT AATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCA AATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACC ACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACT GCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATA >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1476nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGATGGAGATGGCGATGGAGATGGAGCAACT GGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAAT GGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAA GCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGG ATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGC CTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGAC ATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTA TTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAG GATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCT GTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCT GTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGT AATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCA AATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACC ACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACT GCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATA >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_1581nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAACCTGATAAAGAATCAGGA GCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGCGAT GGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGT GACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACA AGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAA TACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAAT GGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTA TTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCC AAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGAT AGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTC CAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTG AAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGAT ACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAAT AAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGAT GGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCA GATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAG >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1581nt ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACG GCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAACCTGATAAAGAATCAGGA GCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGCGAT GGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGT GACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACA AGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAA TACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAAT GGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTA TTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCC AAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGAT AGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTC CAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTG AAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGAT ACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAAT AAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGAT GGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCA GATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_3930nt GCAGTCGGGTCTGGCCCCAGTCGACTCCAGCCAGGCGGGGCTCCAAGCCGAGACTCCTGCACGCCCGGCCCGAAGCTAGCCCGACACCCT CAGCTGAGTCCTCCGCCGTCCCAGCATTCCCTGCGTCCCTACCATCGAGAGCAGCTTCCGGCGTGGCTGGTGTAGGCGGGTGGAGAAGGA TCGGGGCCCTCGCCGCTCTGTCTCATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCT GAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAA GAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATC AGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAA GAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGA ATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGA GATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGAT AGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTC TCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAAC ACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTAC TAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCA AGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGA GGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAG TAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAA TGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGC AGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGA CTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGC TGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGAT AGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATA TGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCT GTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCT TGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGC AAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATT TTATTTTTGTTTATACCAGTCTTAAAGATCCAGGTTCTGAATAAAAAAATTAATTGATACAATTGATGTGTGCTGGGGTTTGGAACTAAA AGTAGTTTCAACAGTGCGTGGGTTATGACATTTCTTATGTTTCTTTGTTCATGTGTGTATTTAGTAGTTAATTTTAAGATGTCCTAGTGA TCTTTAAAAGAAAAATATTGTACCATTTTTTAGAATTACACTTTCACCTTTCTTTTTGCAATTGAAAGTGATGATGTCAAAGTGGGATTT CTGTACTCCAAGGCCCCACCCCCAATTTAGCAAGCAGAAAAACGTTCCTTGTATCACTTTACCTTGGATAATTGGGTGCCATTAACACAA ACAGGTCACAATCCTGCTGTTTTCTAGCCCTGTCCACCATAATGAGATTCAGGAAACATCCTGTCAGCCTCCTGGAAAGCATCCTTGTCT CCTTAGTATTTCATTTACAAACTACCTCTTAACAGAGACTGCTTTTCAAATTGGCCAATCTTACCTGTTTTGTGTTGTGATTGCATTTTC AAAGAGTAATTATTTTCAGCATATACAGTTTTGAAACCTGTAGCTCCTATGCAATAACATAGTTCTATAGACATTATTTGGGGGAAATGT AGTAATAACTCAATCTATGTTGCTGTCCTAGAAAGGAAATTGCATGATGAATCTAGATTGTCTTTAGAGTAAAGAAACACATTCAAATTC CTGTAACTTATCACTTTCAGTGAGTAAATTTACTTATACCAAAGGGGATTTTTTTTCTTTCAGGAATCTAAGGAAATTTACTTTTTAACC TGAGAAAAAAACTTGGTTCTGCTTTATATAAACAGTAGAGATTATTGTACTATAAGTGATTTTGCCTTTTTGCCAAAATCCTGGAACTCA TCTATAATTAACCTCTTCGGAGCAATACCTTAGGTTGGGCCTTGCTTTACTACTTAGAAATAGCTAAATTTCAATTTTAAAAATCTTTGT GTGTTATAACTGTTAAATTATTCAATAATACTTAGGGTTTACTTTCTTATTTAAATCACTTATTTAGTTTACCGACTTCATTTTTCTTTG GATTTAGAAGAAGCAATTATGGAAAAACTTGGTAATCTCTCTCAACCTATAACCTTACACAGGAAGAATTAGAGTTTAATAATTTTTAAT TCTTTTATTGTATGTTACTTTTATTACACCAGTTTGGGGGAAAATCTTCATAAAATTGTATCAGTTTTATTCAGTGTTCTCTAAGGTGAT ACCTTTTAATTTTGAAAGACTAAATAATTTTAATCGAGAATTTCCAGTCTTTCAGTCTGATCTATTTAATTCACTACTTGTTACATAATC CAGTGAAAACTCTACTTGTTGAAATTATGACATAAAGATCTTGCAGCTTTATTTGAGTATTTGTTCTTTTGTGTAGTTTCCATCTTTTAA AATATTTAAAATATTTTCAAGATAAAGTATTATCTTCTCTGCAAAAATTCCTGGAGTAATTTTCTCTCATAATATTTGAAGTCAGTGGTT CTCAGTTGTATTAGTGGGGTAACTACATCAAAATAAATAAAGTCTTATTTTTAAAATGCAAATTTTAGACCATACTCCCAGTGATTCTTA >In-frame_METAP2_ENST00000323666_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_2308nt GCAGTCGGGTCTGGCCCCAGTCGACTCCAGCCAGGCGGGGCTCCAAGCCGAGACTCCTGCACGCCCGGCCCGAAGCTAGCCCGACACCCT CAGCTGAGTCCTCCGCCGTCCCAGCATTCCCTGCGTCCCTACCATCGAGAGCAGCTTCCGGCGTGGCTGGTGTAGGCGGGTGGAGAAGGA TCGGGGCCCTCGCCGCTCTGTCTCATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCT GAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAA GAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATC AGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAA GAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGA ATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGA GATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGAT AGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTC TCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAAC ACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTAC TAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCA AGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGA GGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAG TAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAA TGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGC AGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGA CTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGC TGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGAT AGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATA TGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCT GTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCT TGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGC AAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATT >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_3731nt ACCATCGAGAGCAGCTTCCGGCGTGGCTGGTGTAGGCGGGTGGAGAAGGATCGGGGCCCTCGCCGCTCTGTCTCATTCCCTCGCGCTCTC TCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCT GCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGAT AAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGAT GGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACGACAAGAATGCGAATACCCACCCACA CAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGA GAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTG GAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCC CATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATT ATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAA TTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAG AAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGG AAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATG AATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAG TATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTAC CAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATT AAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTT ACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCA AGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATA TATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTA GGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATT TTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGT ATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAG TCTTAAAGATCCAGGTTCTGAATAAAAAAATTAATTGATACAATTGATGTGTGCTGGGGTTTGGAACTAAAAGTAGTTTCAACAGTGCGT GGGTTATGACATTTCTTATGTTTCTTTGTTCATGTGTGTATTTAGTAGTTAATTTTAAGATGTCCTAGTGATCTTTAAAAGAAAAATATT GTACCATTTTTTAGAATTACACTTTCACCTTTCTTTTTGCAATTGAAAGTGATGATGTCAAAGTGGGATTTCTGTACTCCAAGGCCCCAC CCCCAATTTAGCAAGCAGAAAAACGTTCCTTGTATCACTTTACCTTGGATAATTGGGTGCCATTAACACAAACAGGTCACAATCCTGCTG TTTTCTAGCCCTGTCCACCATAATGAGATTCAGGAAACATCCTGTCAGCCTCCTGGAAAGCATCCTTGTCTCCTTAGTATTTCATTTACA AACTACCTCTTAACAGAGACTGCTTTTCAAATTGGCCAATCTTACCTGTTTTGTGTTGTGATTGCATTTTCAAAGAGTAATTATTTTCAG CATATACAGTTTTGAAACCTGTAGCTCCTATGCAATAACATAGTTCTATAGACATTATTTGGGGGAAATGTAGTAATAACTCAATCTATG TTGCTGTCCTAGAAAGGAAATTGCATGATGAATCTAGATTGTCTTTAGAGTAAAGAAACACATTCAAATTCCTGTAACTTATCACTTTCA GTGAGTAAATTTACTTATACCAAAGGGGATTTTTTTTCTTTCAGGAATCTAAGGAAATTTACTTTTTAACCTGAGAAAAAAACTTGGTTC TGCTTTATATAAACAGTAGAGATTATTGTACTATAAGTGATTTTGCCTTTTTGCCAAAATCCTGGAACTCATCTATAATTAACCTCTTCG GAGCAATACCTTAGGTTGGGCCTTGCTTTACTACTTAGAAATAGCTAAATTTCAATTTTAAAAATCTTTGTGTGTTATAACTGTTAAATT ATTCAATAATACTTAGGGTTTACTTTCTTATTTAAATCACTTATTTAGTTTACCGACTTCATTTTTCTTTGGATTTAGAAGAAGCAATTA TGGAAAAACTTGGTAATCTCTCTCAACCTATAACCTTACACAGGAAGAATTAGAGTTTAATAATTTTTAATTCTTTTATTGTATGTTACT TTTATTACACCAGTTTGGGGGAAAATCTTCATAAAATTGTATCAGTTTTATTCAGTGTTCTCTAAGGTGATACCTTTTAATTTTGAAAGA CTAAATAATTTTAATCGAGAATTTCCAGTCTTTCAGTCTGATCTATTTAATTCACTACTTGTTACATAATCCAGTGAAAACTCTACTTGT TGAAATTATGACATAAAGATCTTGCAGCTTTATTTGAGTATTTGTTCTTTTGTGTAGTTTCCATCTTTTAAAATATTTAAAATATTTTCA AGATAAAGTATTATCTTCTCTGCAAAAATTCCTGGAGTAATTTTCTCTCATAATATTTGAAGTCAGTGGTTCTCAGTTGTATTAGTGGGG TAACTACATCAAAATAAATAAAGTCTTATTTTTAAAATGCAAATTTTAGACCATACTCCCAGTGATTCTTAGTTGGTCTTTTTGGAATGA >In-frame_METAP2_ENST00000546753_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_2109nt ACCATCGAGAGCAGCTTCCGGCGTGGCTGGTGTAGGCGGGTGGAGAAGGATCGGGGCCCTCGCCGCTCTGTCTCATTCCCTCGCGCTCTC TCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAAGAAGGAGCT GCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGAT AAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGATGAAGAT GGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACGACAAGAATGCGAATACCCACCCACA CAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGA GAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTG GAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCC CATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATT ATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAA TTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAG AAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGG AAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATG AATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAG TATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTAC CAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATT AAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTT ACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCA AGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATA TATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTA GGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATT TTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGT ATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAG >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_3662nt GTCTCATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCA GACGACAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCA GGGGAACAGGAACCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGA GATGAAGATGATGAAGCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAA GAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAA GAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATG ATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGT TCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGA ACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCT ACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCT CAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCA GAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATA AGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGAC AATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGA GCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGG GACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTG GCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAG ATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAA TATGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTAC CTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAAT CTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTT GCAAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTA TTTTATTTTTGTTTATACCAGTCTTAAAGATCCAGGTTCTGAATAAAAAAATTAATTGATACAATTGATGTGTGCTGGGGTTTGGAACTA AAAGTAGTTTCAACAGTGCGTGGGTTATGACATTTCTTATGTTTCTTTGTTCATGTGTGTATTTAGTAGTTAATTTTAAGATGTCCTAGT GATCTTTAAAAGAAAAATATTGTACCATTTTTTAGAATTACACTTTCACCTTTCTTTTTGCAATTGAAAGTGATGATGTCAAAGTGGGAT TTCTGTACTCCAAGGCCCCACCCCCAATTTAGCAAGCAGAAAAACGTTCCTTGTATCACTTTACCTTGGATAATTGGGTGCCATTAACAC AAACAGGTCACAATCCTGCTGTTTTCTAGCCCTGTCCACCATAATGAGATTCAGGAAACATCCTGTCAGCCTCCTGGAAAGCATCCTTGT CTCCTTAGTATTTCATTTACAAACTACCTCTTAACAGAGACTGCTTTTCAAATTGGCCAATCTTACCTGTTTTGTGTTGTGATTGCATTT TCAAAGAGTAATTATTTTCAGCATATACAGTTTTGAAACCTGTAGCTCCTATGCAATAACATAGTTCTATAGACATTATTTGGGGGAAAT GTAGTAATAACTCAATCTATGTTGCTGTCCTAGAAAGGAAATTGCATGATGAATCTAGATTGTCTTTAGAGTAAAGAAACACATTCAAAT TCCTGTAACTTATCACTTTCAGTGAGTAAATTTACTTATACCAAAGGGGATTTTTTTTCTTTCAGGAATCTAAGGAAATTTACTTTTTAA CCTGAGAAAAAAACTTGGTTCTGCTTTATATAAACAGTAGAGATTATTGTACTATAAGTGATTTTGCCTTTTTGCCAAAATCCTGGAACT CATCTATAATTAACCTCTTCGGAGCAATACCTTAGGTTGGGCCTTGCTTTACTACTTAGAAATAGCTAAATTTCAATTTTAAAAATCTTT GTGTGTTATAACTGTTAAATTATTCAATAATACTTAGGGTTTACTTTCTTATTTAAATCACTTATTTAGTTTACCGACTTCATTTTTCTT TGGATTTAGAAGAAGCAATTATGGAAAAACTTGGTAATCTCTCTCAACCTATAACCTTACACAGGAAGAATTAGAGTTTAATAATTTTTA ATTCTTTTATTGTATGTTACTTTTATTACACCAGTTTGGGGGAAAATCTTCATAAAATTGTATCAGTTTTATTCAGTGTTCTCTAAGGTG ATACCTTTTAATTTTGAAAGACTAAATAATTTTAATCGAGAATTTCCAGTCTTTCAGTCTGATCTATTTAATTCACTACTTGTTACATAA TCCAGTGAAAACTCTACTTGTTGAAATTATGACATAAAGATCTTGCAGCTTTATTTGAGTATTTGTTCTTTTGTGTAGTTTCCATCTTTT AAAATATTTAAAATATTTTCAAGATAAAGTATTATCTTCTCTGCAAAAATTCCTGGAGTAATTTTCTCTCATAATATTTGAAGTCAGTGG TTCTCAGTTGTATTAGTGGGGTAACTACATCAAAATAAATAAAGTCTTATTTTTAAAATGCAAATTTTAGACCATACTCCCAGTGATTCT >In-frame_METAP2_ENST00000261220_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_2040nt GTCTCATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCA GACGACAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCA GGGGAACAGGAACCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGA GATGAAGATGATGAAGCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAA GAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAA GAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATG ATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGT TCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGA ACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCT ACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCT CAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCA GAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATA AGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGAC AATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGA GCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGG GACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTG GCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAG ATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAA TATGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTAC CTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAAT CTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTT GCAAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTA >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_3618nt ATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGA CAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGATGG AGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGT TCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTG GAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACA AGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAAT AAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGA CACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCAC TTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATAT AGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAA GAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCA TGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAG TAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGA AGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACC ACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACA GCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTT TGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAG ATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTA CAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGG CTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCAT TTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCT TGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAGTCTTAAAGATCCAGGTTCTGAAT AAAAAAATTAATTGATACAATTGATGTGTGCTGGGGTTTGGAACTAAAAGTAGTTTCAACAGTGCGTGGGTTATGACATTTCTTATGTTT CTTTGTTCATGTGTGTATTTAGTAGTTAATTTTAAGATGTCCTAGTGATCTTTAAAAGAAAAATATTGTACCATTTTTTAGAATTACACT TTCACCTTTCTTTTTGCAATTGAAAGTGATGATGTCAAAGTGGGATTTCTGTACTCCAAGGCCCCACCCCCAATTTAGCAAGCAGAAAAA CGTTCCTTGTATCACTTTACCTTGGATAATTGGGTGCCATTAACACAAACAGGTCACAATCCTGCTGTTTTCTAGCCCTGTCCACCATAA TGAGATTCAGGAAACATCCTGTCAGCCTCCTGGAAAGCATCCTTGTCTCCTTAGTATTTCATTTACAAACTACCTCTTAACAGAGACTGC TTTTCAAATTGGCCAATCTTACCTGTTTTGTGTTGTGATTGCATTTTCAAAGAGTAATTATTTTCAGCATATACAGTTTTGAAACCTGTA GCTCCTATGCAATAACATAGTTCTATAGACATTATTTGGGGGAAATGTAGTAATAACTCAATCTATGTTGCTGTCCTAGAAAGGAAATTG CATGATGAATCTAGATTGTCTTTAGAGTAAAGAAACACATTCAAATTCCTGTAACTTATCACTTTCAGTGAGTAAATTTACTTATACCAA AGGGGATTTTTTTTCTTTCAGGAATCTAAGGAAATTTACTTTTTAACCTGAGAAAAAAACTTGGTTCTGCTTTATATAAACAGTAGAGAT TATTGTACTATAAGTGATTTTGCCTTTTTGCCAAAATCCTGGAACTCATCTATAATTAACCTCTTCGGAGCAATACCTTAGGTTGGGCCT TGCTTTACTACTTAGAAATAGCTAAATTTCAATTTTAAAAATCTTTGTGTGTTATAACTGTTAAATTATTCAATAATACTTAGGGTTTAC TTTCTTATTTAAATCACTTATTTAGTTTACCGACTTCATTTTTCTTTGGATTTAGAAGAAGCAATTATGGAAAAACTTGGTAATCTCTCT CAACCTATAACCTTACACAGGAAGAATTAGAGTTTAATAATTTTTAATTCTTTTATTGTATGTTACTTTTATTACACCAGTTTGGGGGAA AATCTTCATAAAATTGTATCAGTTTTATTCAGTGTTCTCTAAGGTGATACCTTTTAATTTTGAAAGACTAAATAATTTTAATCGAGAATT TCCAGTCTTTCAGTCTGATCTATTTAATTCACTACTTGTTACATAATCCAGTGAAAACTCTACTTGTTGAAATTATGACATAAAGATCTT GCAGCTTTATTTGAGTATTTGTTCTTTTGTGTAGTTTCCATCTTTTAAAATATTTAAAATATTTTCAAGATAAAGTATTATCTTCTCTGC AAAAATTCCTGGAGTAATTTTCTCTCATAATATTTGAAGTCAGTGGTTCTCAGTTGTATTAGTGGGGTAACTACATCAAAATAAATAAAG TCTTATTTTTAAAATGCAAATTTTAGACCATACTCCCAGTGATTCTTAGTTGGTCTTTTTGGAATGAGCCATAGGTAATGTTTATGTCCA >In-frame_METAP2_ENST00000550777_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_1996nt ATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGA CAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGATGG AGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGT TCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACAGCTGCTTG GAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACA AGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGCAAGTTAAT AAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGA CACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTTACTGTCAC TTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTAGATGATAT AGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAAGAATCCAA GAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTTAGTGATCA TGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGAAAAGTCAG TAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAACTCTCTAGA AGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAAGATGAACC ACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCACGGCTACA GCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAACAGACTTT TGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGTGATATTAG ATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATATATAAAGCTAAGATGTGGATTTA CAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAAGGTAAGGG CTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGAATTATCAT TTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGTATGACTCCTTTTTACTGTATTCT TGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAGTCTTAAAGATCCAGGTTCTGAAT >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000436874_chr12_95689827_+_3716nt CGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAA GAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAA CCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGAT GAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCT CCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACA GCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCA CATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGC AAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAAT GCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTT ACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTA GATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAA GAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTT AGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGA AAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAAC TCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAA GATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCA CGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAA CAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGT GATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATATATAAAGCTAAGATG TGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAA GGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGA ATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGTATGACTCCTTTTTAC TGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAGTCTTAAAGATCCAGG TTCTGAATAAAAAAATTAATTGATACAATTGATGTGTGCTGGGGTTTGGAACTAAAAGTAGTTTCAACAGTGCGTGGGTTATGACATTTC TTATGTTTCTTTGTTCATGTGTGTATTTAGTAGTTAATTTTAAGATGTCCTAGTGATCTTTAAAAGAAAAATATTGTACCATTTTTTAGA ATTACACTTTCACCTTTCTTTTTGCAATTGAAAGTGATGATGTCAAAGTGGGATTTCTGTACTCCAAGGCCCCACCCCCAATTTAGCAAG CAGAAAAACGTTCCTTGTATCACTTTACCTTGGATAATTGGGTGCCATTAACACAAACAGGTCACAATCCTGCTGTTTTCTAGCCCTGTC CACCATAATGAGATTCAGGAAACATCCTGTCAGCCTCCTGGAAAGCATCCTTGTCTCCTTAGTATTTCATTTACAAACTACCTCTTAACA GAGACTGCTTTTCAAATTGGCCAATCTTACCTGTTTTGTGTTGTGATTGCATTTTCAAAGAGTAATTATTTTCAGCATATACAGTTTTGA AACCTGTAGCTCCTATGCAATAACATAGTTCTATAGACATTATTTGGGGGAAATGTAGTAATAACTCAATCTATGTTGCTGTCCTAGAAA GGAAATTGCATGATGAATCTAGATTGTCTTTAGAGTAAAGAAACACATTCAAATTCCTGTAACTTATCACTTTCAGTGAGTAAATTTACT TATACCAAAGGGGATTTTTTTTCTTTCAGGAATCTAAGGAAATTTACTTTTTAACCTGAGAAAAAAACTTGGTTCTGCTTTATATAAACA GTAGAGATTATTGTACTATAAGTGATTTTGCCTTTTTGCCAAAATCCTGGAACTCATCTATAATTAACCTCTTCGGAGCAATACCTTAGG TTGGGCCTTGCTTTACTACTTAGAAATAGCTAAATTTCAATTTTAAAAATCTTTGTGTGTTATAACTGTTAAATTATTCAATAATACTTA GGGTTTACTTTCTTATTTAAATCACTTATTTAGTTTACCGACTTCATTTTTCTTTGGATTTAGAAGAAGCAATTATGGAAAAACTTGGTA ATCTCTCTCAACCTATAACCTTACACAGGAAGAATTAGAGTTTAATAATTTTTAATTCTTTTATTGTATGTTACTTTTATTACACCAGTT TGGGGGAAAATCTTCATAAAATTGTATCAGTTTTATTCAGTGTTCTCTAAGGTGATACCTTTTAATTTTGAAAGACTAAATAATTTTAAT CGAGAATTTCCAGTCTTTCAGTCTGATCTATTTAATTCACTACTTGTTACATAATCCAGTGAAAACTCTACTTGTTGAAATTATGACATA AAGATCTTGCAGCTTTATTTGAGTATTTGTTCTTTTGTGTAGTTTCCATCTTTTAAAATATTTAAAATATTTTCAAGATAAAGTATTATC TTCTCTGCAAAAATTCCTGGAGTAATTTTCTCTCATAATATTTGAAGTCAGTGGTTCTCAGTTGTATTAGTGGGGTAACTACATCAAAAT AAATAAAGTCTTATTTTTAAAATGCAAATTTTAGACCATACTCCCAGTGATTCTTAGTTGGTCTTTTTGGAATGAGCCATAGGTAATGTT >In-frame_METAP2_ENST00000551840_chr12_95889874_+_VEZT_ENST00000261219_chr12_95689827_+_2094nt CGCGCTCTCTCGGGCAACATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGGGAA GAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGGGGAACAGGAA CCTGATAAAGAATCAGGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAAGATGAT GAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCT CCCTCAGTTCCAATATGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGGCGAACA GCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCA CATCGACAAGTTAGAAAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGTTCACGC AAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCTACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAAT GCCGGTGACACAACAGTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATTATTGACTGTGCTTTT ACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTAAAAGATGCTACTAACACTGGAATAAAGGAATTAGAAGCTTATGTA GATGATATAGATATTGATAGTGATTTCAGAAAGGATGATTTTTATTACTTGTCTCAAGAAGACAAAGAGAGACAGAAGCGTGAGCATGAA GAATCCAAGAGGGTGCTCCAAGAATTAAAATCTGTGCTGGGATTTAAAGCTTCAGAGGCAGAAAGGCAGAAGTGGAAGCAACTTCTATTT AGTGATCATGCCGTGTTGAAATCCTTGTCTCCTGTAGACCCAGTGGAACCCATAAGTAATTCAGAACCATCAATGAATTCAGATATGGGA AAAGTCAGTAAAAATGATACTGAAGAGGAAAGTAATAAATCCGCCACAACAGACAATGAAATAAGTAGGACTGAGTATTTATGTGAAAAC TCTCTAGAAGGTAAAAATAAAGATAATTCTTCAAATGAAGTCTTCCCCCAAGGAGCAGAAGAAAGAATGTGTTACCAATGTGAGAGTGAA GATGAACCACAAGCAGATGGAAGTGGTCTGACCACTGCCCCTCCAACTCCCAGGGACTCATTACAGCCCTCCATTAAGCAGAGGCTGGCA CGGCTACAGCTGTCACCAGATTTTACCTTCACTGCTGGCCTTGCTGCAGAAGTGGCTGCTAGATCTCTCTCCTTTACCACCATGCAGGAA CAGACTTTTGGTGGTGAGGAGGAAGAACAAATAATAGAAGAAAATAAAAATGAGATAGAAGAAAAGTAAGAACCAAGATTCATATGAAGT GATATTAGATTGTTCCTTTTACAAAAGTGTTTAGCTTCAAGACTGGAAAGGGAATATGAGTGTAAGTTTACTATATATAAAGCTAAGATG TGGATTTACAGGAAGAACCCTGGTTTGAATAACTGATCTGAAATTAGTAGTTACCTGTAAATGGCAGATCTTTTAGGAAAATAAGAGAAA GGTAAGGGCTCTTTTGAATAAACTGCTGTTTTATTTGTGGCACAACTGATCAATCTTGGAAATTCTTTAAGTATTTTTAATAAGAAATGA ATTATCATTTCTTGCCAGAATTTGCTACCTTAAGGTGATTGGGAAAATTCTGTTGCAAGAACATTAACATTTAGTATGACTCCTTTTTAC TGTATTCTTGCAGTTAATAACTGCAGCTATTATGTTAATAACAAGTTGTTTGTATTTTATTTTTGTTTATACCAGTCTTAAAGATCCAGG |
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FusionGenePPI for METAP2_VEZT |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| METAP2 | EIF2AK2, CALM1, APP, EEF2K, MTOR, HMGA1, DAK, GAPDH, GBP1, NPEPPS, C1QB, BSG, OTUD6B, C1QTNF9, GNAS, LPPR2, ACTL6A, TEKT2, PLIN5, CHD3, NTRK1, KRAS, XPO1, YWHAE, SUCLA2, GPBP1L1, TMEM213, DDX28, CCT7, SLC25A25, LILRB3, ASB6, FCRL2, CCT3, RGS2, TMEM108, MRPL35, MECP2, CUL5, PVR, DLK2, TMEM194A, SUN2, TNFRSF19, GRIA3, TRIM25 | VEZT | MYO7A, CTNNA1, CTNNB1, CDH1, ELAVL1, PLEKHO2, TCTN2, TCTN3, EVC2, TMEM17, TMEM216, CTDNEP1, TPTE, VIPR2, C3AR1, TMED6, GPR21, FZD10, DLK2, CHRM4, IPPK |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for METAP2_VEZT |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | METAP2 | P50579 | DB01422 | Nitroxoline | Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175} | small molecule | approved |
| Hgene | METAP2 | P50579 | DB00134 | Methionine | Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175} | small molecule | approved|nutraceutical |
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RelatedDiseases for METAP2_VEZT |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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