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Fusion gene ID: 21518 |
FusionGeneSummary for MED1_RHBDL3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MED1_RHBDL3 | Fusion gene ID: 21518 | Hgene | Tgene | Gene symbol | MED1 | RHBDL3 | Gene ID | 8930 | 162494 |
| Gene name | methyl-CpG binding domain 4, DNA glycosylase | rhomboid like 3 | |
| Synonyms | MED1 | RHBDL4|VRHO | |
| Cytomap | 3q21.3 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | methyl-CpG-binding domain protein 43,N(4)-ethenocytosine glycosylaseG/5-fluorouracil mismatch glycosylase with biphasic kineticsG/T mismatch glycosylaseG/U mismatch glycosylasemethyl-CpG binding domain protein 4methyl-CpG-binding endonuclease 1meth | rhomboid-related protein 3rhomboid, veinlet-like 3rhomboid, veinlet-like 4ventrhoid transmembrane protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q15648 | P58872 | |
| Ensembl transtripts involved in fusion gene | ENST00000394287, ENST00000300651, | ENST00000269051, ENST00000538145, ENST00000536287, | |
| Fusion gene scores | * DoF score | 25 X 11 X 9=2475 | 5 X 4 X 4=80 |
| # samples | 25 | 5 | |
| ** MAII score | log2(25/2475*10)=-3.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MED1 [Title/Abstract] AND RHBDL3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-E2-A14Y-01A | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000394287 | ENST00000269051 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| In-frame | ENST00000394287 | ENST00000538145 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| In-frame | ENST00000394287 | ENST00000536287 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| In-frame | ENST00000300651 | ENST00000269051 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| In-frame | ENST00000300651 | ENST00000538145 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
| In-frame | ENST00000300651 | ENST00000536287 | MED1 | chr17 | 37604051 | - | RHBDL3 | chr17 | 30615811 | + |
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FusionProtFeatures for MED1_RHBDL3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MED1 | RHBDL3 |
| Component of the Mediator complex, a coactivatorinvolved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge toconvey information from gene-specific regulatory proteins to thebasal RNA polymerase II transcription machinery. Mediator isrecruited to promoters by direct interactions with regulatoryproteins and serves as a scaffold for the assembly of a functionalpreinitiation complex with RNA polymerase II and the generaltranscription factors (PubMed:10406464, PubMed:11867769,PubMed:12037571, PubMed:12218053, PubMed:12556447,PubMed:14636573, PubMed:15340084, PubMed:15471764,PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as acoactivator for GATA1-mediated transcriptional activation duringerythroid differentiation of K562 erythroleukemia cells(PubMed:24245781). {ECO:0000269|PubMed:10406464,ECO:0000269|PubMed:11867769, ECO:0000269|PubMed:12037571,ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:12556447,ECO:0000269|PubMed:14636573, ECO:0000269|PubMed:15340084,ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:15989967,ECO:0000269|PubMed:16574658, ECO:0000269|PubMed:24245781,ECO:0000269|PubMed:9653119}. | May be involved in regulated intramembrane proteolysisand the subsequent release of functional polypeptides from theirmembrane anchors. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 164_184 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 218_238 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 250_270 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 274_294 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 303_325 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 338_358 | 98 | 405 | Transmembrane | Helical |
| Tgene | >RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 371_391 | 98 | 405 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 1078_1482 | 44 | 1582 | Compositional bias | Note=Ser-rich |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 1496_1529 | 44 | 1582 | Compositional bias | Note=Lys-rich |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 1078_1482 | 44 | 557 | Compositional bias | Note=Ser-rich |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 1496_1529 | 44 | 557 | Compositional bias | Note=Lys-rich |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 604_608 | 44 | 1582 | Motif | Note=LXXLL motif 1 |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 645_649 | 44 | 1582 | Motif | Note=LXXLL motif 2 |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 604_608 | 44 | 557 | Motif | Note=LXXLL motif 1 |
| Hgene | >MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 645_649 | 44 | 557 | Motif | Note=LXXLL motif 2 |
| Tgene | RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 34_69 | 98 | 405 | Domain | EF-hand 1 |
| Tgene | RHBDL3 | chr17:37604051 | chr17:30615811 | ENST00000269051 | + | 2 | 9 | 70_105 | 98 | 405 | Domain | EF-hand 2 |
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FusionGeneSequence for MED1_RHBDL3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_351aa MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETL PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQ LLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_1053nt ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGC AACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTG CCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTT GCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCAC CCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAG CTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCA GTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATG AACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGG CTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGC GTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_4691nt TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACA GCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTA TCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCA TGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTT ACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAAC ACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGG CCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCT CTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGA GCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTG GCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGG CCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGCTGCCGCCTCCCCCCTGAG GGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTCATCACCAGCTCAGCTAGG CCGGGCAGACAAGGACAGAAGACTCTGGGCCACTGTAATGTTTGTGTTTAGATTTGGACACACAGTGGAGACCCTTTTCTGAAAGGCATC TGGCGGAGGAGTTGATGTGGCTGCTGTCGTTTTTCTCGGCTGCTCTGATGACATCGGGCCAGGGTGAAGGTCTGGGGTGGGGTGTGAGAG TGGCCCTCCCTCACCTGGGCTGGGCTTCTTCCATGGGGCCAGGGGGTGCCCCCTCACTGCTGCGGATTGAGCAGCAGCTTCTTCCTCCTC CTCTACCCTCAGAGACCCTAAGAGACATGGGAAGGCTCGAAGGTTGTTGCGTCCAGGCATGGCCCCTCTCTAGCTCAGAAATAATTGCAG GCCATGTGGTGTCTCCTTGACACCTGCTGTGTCTGGGGCTCCAGTAAGAAGAGGGCCTACTGGACATGTCAGCTGTGACCTGGCTGAAAC CAGGGTGCCCTCCTGGGCTGGTTGGTGTGCACCGGGGCATGATCTGTTGTGCCTGGGTTGGGCAGAGCAGGGAGCCTGTAGGCTCTAGGA CCCCTCTTGTGCTGGGGGTACCCAGTGAGAGGGACCCATGCAGGGGGAATAAACTTCATTCCAAGTTCCACCCTGGAGAAGACAGACCCA GGACCAGCTTCAGACTTCTCCCTCCCTTTCTTCCAGGATATTGGCATCTCACACGGGTGCCCCAGCCTCCATGCCCAGCCTTGTTTTAGG GTCTTTTTCTTTCCTTTTGCTGCCCTGACACTACTTTGTGCCTCTCTTTGGTTATGGAGACAGTGTTTTGAAACATTCATGCGTGTGTGT GTGTGTGTGCGTATATGTGTGTATGTGATGGGAAAGGTAACTGAGGCACGACAGCGCCTGCAGAGAAGGCATGGAGGATGCAGGGGGCCC ATGTGGGCATCCGTGAGAGGTGGCAGACCGTGGTGTGCTGTGGTTGCTGAATGTCCTTGCTTTGACAAAGCCTGCCCCCTTCCTTCCCAT CTCCTGTCCCTTCCACACCTGCCCCTGAGCATCACTGACCGGTGGCAGAATGGCCCTGCTGGAGGGAGAGCTCAAGCCCTCCAAGGATCC CTGGATGCTGAGGTTTGCCAGGTTCAGCTCTTGTTTCCGTCTGAGATGGCCTTCATATCCAAAAAGGTTCCATCCTATCTCCCTTAGGAG AGAAAGAGCTTTGGGGGCGCAAGAGAGGCTGGGGTAGGAATGTTGAGGCCATGTGTCCATTTAAGTTAGGGGGACAGGAGGCTACAGGAA GAGGAATTCCAGTTTAGTTGGAAAACTTTGCCTCAGGAGAATTGTTGGGTGCATGGATGAACCTCAGAGGGAGGGCAGCCAGTAGCCTCG GAGGCTTGGATGCGGGAGAGAACATGGTGGTTATCAAATCCACCCCACCCCATTACACAGGTGAGAAAACAAGATGGAGGGAATGACCCT CCTAACAGGAGCTGGTGCAGGCCCCGAATGGAGGGCATGAGGATGACCTTTGACAAAAGATGACACTCCCTTTATCGTGCTCTTGGAATT CTCAACCACTGACAGCCCAGAAGAACAAAGAACGCCAGGCCTGGGAGGAGGCAGGGGGGCTGGGCGTGTCCAGAAACAGGGGCAGGAGTG TGGGAACGGTCTTCCTCCAGCCTGGTGCCCATCCTGGCCCTTGAGTGTAGCAGGGTCCAGGGTCAGTCAGGCCAGGCATTTGGGGTCTTG GGCCACAGTGGCTTCCCATCCTGGTGACTACATGTAAATGGGCTCACTCACTCACTGGCAGGCGAGGCCCAGCCATACCGCATCTTGGCC CACTGCTAAATAGATTGCCCTGGCCTCATCCACATATGTAGTTCCCTAGGTCCTGCTCCCCTGCACCAGTGCCATGCTGAGGGCCGCAGC CTGTGGCACTGTGGGCCCACGCCTTTGGCGGTGTTGCGTCAGCCTGGGGCGTCTTGTGTGTGCCCTGCCCACCGTTCTCTGCCCTAGTGA TAGAAAGATGTAGATGGAAGTCAGTGCCTCAGAGGAGGAGGCTCTGAGGCTGTGGAGCTGGGCTCAGGGAAGACCAGGGGAGGATGCAGA AGGAGTCAGGACATTGCTGCCTCTGCCTGGGCTGCAGCCGCACTAAGCTGAGCGATGAGGTCCTTTCCTGGAGGGATGGAGAATCCCCTC CAGATTCCTGTCCTGGCCCCTGGGGATTCTGTGGTGTGGGTGGAATGAGCAGAGTGCCACCTCTGTCTGGTATGACCTGGAGAGGGGGCT TCCTCTCTTAGGGGTGAGAAAGCATTGAACTAGAAGATTCTAGAAATCCCTCATAGAAGCACTCAGCTCCCTCGGGGACTCCCAGGGAAG CTTGTTACTGAGAAGGACAGTGGAGGCGGAATCGTGTCTCCCACCATGTTAAGTGTGTCCTCTGCTGCCAAGGACCCTCGTCTACACCTT AGACCACCAGCCCCAGCTGTTCTCTGTCAGCACACCCACCTCCATCCCCTCTCCCAACCATGACTTCCAAGCGGGGCCACAGGGTGGGGT CATAGGGTCACTTCACCTGACCCAGGCCTCTCCCCAGGTCAGGAGGCAGCTGTCTGGTCAGAGGGGTTCTCTTTGTGGCATCTGGCTTTC TCCTCAGCAGGTCCCACCACCCTCTCAGCAGCACTTCCCCATGGCCAAGGCTGGCCGTGTCCTCTGTGCCTCTTTCCTTGTCTGAGGTGG CTGCCAGCCCAGGGGGTGGTGTGTAAATCTTCAGGCTGGTGGAGGTAGGTTGGCCTTTTATCCACAGGATACAGAAACTGAAAGCTGGGG AATCCCCAAACAGCAGCCATAGACTCACTGGCTCTCATTAAACGGGAGAGGAATCACAGAAACTGGGGAAGGGAAAACAAACCTTCAAAG GAGAAATTTCGCTTTAATGACACCATTCATCATTCGTTTTTTAATTAGGAAAAGCTCCCTAATGAGGCTCTTTTGCCAGCTAATAGGACT CTCGATTTCCATGAGAACCATTCTTGCCCAGAGGATTAGGGGAGCTGTTGCTCACCACACCAGGATCTTCCCCCAGCGTCCAATTTAATT TGCAAATACGTAATGCAGATTCCCTGGGTGCCGTGAAAGCCTTTCCTGGCATCATTCATGTTGCTCCCCGTGCTGGCTGGAAAGCACGGT TCTCCTCTGCCTTAAAAACAGTGCCCAACAGTGAACTGCCCCTCCGAGGACTTGAGTAAGTGGAAAAAACAAAACACAGACTGCAATGTT TGTTTCTAAGTATTTTTGTATTGTGTACATTCTGTATATTTTTGTTGTAACATATTATTTGAGCACAGATTCCATTAAATATTTTTTTTC >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_1393nt TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACA GCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTA TCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCA TGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTT ACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAAC ACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGG CCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCT CTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGA GCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTG GCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGG CCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGCTGCCGCCTCCCCCCTGAG GGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTCATCACCAGCTCAGCTAGG >In-frame_MED1_ENST00000394287_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_4686nt TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGAGCAACAAGCGTTCCAACA GCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGAGCCTCTCGCAGCGACTTA TCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCTGCCCCCCACCCTGGTTCA TGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGCAGGTAACTCATCCACGTT ACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCATGCATGCAGGGATAGAAC ACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAATTGGGCTTGTCTACGTGG CCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAGGGGTGTATGCTCTCGTCT CTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTGTGGCCCTTATCTGTATGA GCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCTTTGTGGCGCACTTGGGTG GCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCACTGTGGTGGATTTTTGTGG CCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGCTGCCGCCTCCCCCCTGAG GGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTCATCACCAGCTCAGCTAGG CCGGGCAGACAAGGACAGAAGACTCTGGGCCACTGTAATGTTTGTGTTTAGATTTGGACACACAGTGGAGACCCTTTTCTGAAAGGCATC TGGCGGAGGAGTTGATGTGGCTGCTGTCGTTTTTCTCGGCTGCTCTGATGACATCGGGCCAGGGTGAAGGTCTGGGGTGGGGTGTGAGAG TGGCCCTCCCTCACCTGGGCTGGGCTTCTTCCATGGGGCCAGGGGGTGCCCCCTCACTGCTGCGGATTGAGCAGCAGCTTCTTCCTCCTC CTCTACCCTCAGAGACCCTAAGAGACATGGGAAGGCTCGAAGGTTGTTGCGTCCAGGCATGGCCCCTCTCTAGCTCAGAAATAATTGCAG GCCATGTGGTGTCTCCTTGACACCTGCTGTGTCTGGGGCTCCAGTAAGAAGAGGGCCTACTGGACATGTCAGCTGTGACCTGGCTGAAAC CAGGGTGCCCTCCTGGGCTGGTTGGTGTGCACCGGGGCATGATCTGTTGTGCCTGGGTTGGGCAGAGCAGGGAGCCTGTAGGCTCTAGGA CCCCTCTTGTGCTGGGGGTACCCAGTGAGAGGGACCCATGCAGGGGGAATAAACTTCATTCCAAGTTCCACCCTGGAGAAGACAGACCCA GGACCAGCTTCAGACTTCTCCCTCCCTTTCTTCCAGGATATTGGCATCTCACACGGGTGCCCCAGCCTCCATGCCCAGCCTTGTTTTAGG GTCTTTTTCTTTCCTTTTGCTGCCCTGACACTACTTTGTGCCTCTCTTTGGTTATGGAGACAGTGTTTTGAAACATTCATGCGTGTGTGT GTGTGTGTGCGTATATGTGTGTATGTGATGGGAAAGGTAACTGAGGCACGACAGCGCCTGCAGAGAAGGCATGGAGGATGCAGGGGGCCC ATGTGGGCATCCGTGAGAGGTGGCAGACCGTGGTGTGCTGTGGTTGCTGAATGTCCTTGCTTTGACAAAGCCTGCCCCCTTCCTTCCCAT CTCCTGTCCCTTCCACACCTGCCCCTGAGCATCACTGACCGGTGGCAGAATGGCCCTGCTGGAGGGAGAGCTCAAGCCCTCCAAGGATCC CTGGATGCTGAGGTTTGCCAGGTTCAGCTCTTGTTTCCGTCTGAGATGGCCTTCATATCCAAAAAGGTTCCATCCTATCTCCCTTAGGAG AGAAAGAGCTTTGGGGGCGCAAGAGAGGCTGGGGTAGGAATGTTGAGGCCATGTGTCCATTTAAGTTAGGGGGACAGGAGGCTACAGGAA GAGGAATTCCAGTTTAGTTGGAAAACTTTGCCTCAGGAGAATTGTTGGGTGCATGGATGAACCTCAGAGGGAGGGCAGCCAGTAGCCTCG GAGGCTTGGATGCGGGAGAGAACATGGTGGTTATCAAATCCACCCCACCCCATTACACAGGTGAGAAAACAAGATGGAGGGAATGACCCT CCTAACAGGAGCTGGTGCAGGCCCCGAATGGAGGGCATGAGGATGACCTTTGACAAAAGATGACACTCCCTTTATCGTGCTCTTGGAATT CTCAACCACTGACAGCCCAGAAGAACAAAGAACGCCAGGCCTGGGAGGAGGCAGGGGGGCTGGGCGTGTCCAGAAACAGGGGCAGGAGTG TGGGAACGGTCTTCCTCCAGCCTGGTGCCCATCCTGGCCCTTGAGTGTAGCAGGGTCCAGGGTCAGTCAGGCCAGGCATTTGGGGTCTTG GGCCACAGTGGCTTCCCATCCTGGTGACTACATGTAAATGGGCTCACTCACTCACTGGCAGGCGAGGCCCAGCCATACCGCATCTTGGCC CACTGCTAAATAGATTGCCCTGGCCTCATCCACATATGTAGTTCCCTAGGTCCTGCTCCCCTGCACCAGTGCCATGCTGAGGGCCGCAGC CTGTGGCACTGTGGGCCCACGCCTTTGGCGGTGTTGCGTCAGCCTGGGGCGTCTTGTGTGTGCCCTGCCCACCGTTCTCTGCCCTAGTGA TAGAAAGATGTAGATGGAAGTCAGTGCCTCAGAGGAGGAGGCTCTGAGGCTGTGGAGCTGGGCTCAGGGAAGACCAGGGGAGGATGCAGA AGGAGTCAGGACATTGCTGCCTCTGCCTGGGCTGCAGCCGCACTAAGCTGAGCGATGAGGTCCTTTCCTGGAGGGATGGAGAATCCCCTC CAGATTCCTGTCCTGGCCCCTGGGGATTCTGTGGTGTGGGTGGAATGAGCAGAGTGCCACCTCTGTCTGGTATGACCTGGAGAGGGGGCT TCCTCTCTTAGGGGTGAGAAAGCATTGAACTAGAAGATTCTAGAAATCCCTCATAGAAGCACTCAGCTCCCTCGGGGACTCCCAGGGAAG CTTGTTACTGAGAAGGACAGTGGAGGCGGAATCGTGTCTCCCACCATGTTAAGTGTGTCCTCTGCTGCCAAGGACCCTCGTCTACACCTT AGACCACCAGCCCCAGCTGTTCTCTGTCAGCACACCCACCTCCATCCCCTCTCCCAACCATGACTTCCAAGCGGGGCCACAGGGTGGGGT CATAGGGTCACTTCACCTGACCCAGGCCTCTCCCCAGGTCAGGAGGCAGCTGTCTGGTCAGAGGGGTTCTCTTTGTGGCATCTGGCTTTC TCCTCAGCAGGTCCCACCACCCTCTCAGCAGCACTTCCCCATGGCCAAGGCTGGCCGTGTCCTCTGTGCCTCTTTCCTTGTCTGAGGTGG CTGCCAGCCCAGGGGGTGGTGTGTAAATCTTCAGGCTGGTGGAGGTAGGTTGGCCTTTTATCCACAGGATACAGAAACTGAAAGCTGGGG AATCCCCAAACAGCAGCCATAGACTCACTGGCTCTCATTAAACGGGAGAGGAATCACAGAAACTGGGGAAGGGAAAACAAACCTTCAAAG GAGAAATTTCGCTTTAATGACACCATTCATCATTCGTTTTTTAATTAGGAAAAGCTCCCTAATGAGGCTCTTTTGCCAGCTAATAGGACT CTCGATTTCCATGAGAACCATTCTTGCCCAGAGGATTAGGGGAGCTGTTGCTCACCACACCAGGATCTTCCCCCAGCGTCCAATTTAATT TGCAAATACGTAATGCAGATTCCCTGGGTGCCGTGAAAGCCTTTCCTGGCATCATTCATGTTGCTCCCCGTGCTGGCTGGAAAGCACGGT TCTCCTCTGCCTTAAAAACAGTGCCCAACAGTGAACTGCCCCTCCGAGGACTTGAGTAAGTGGAAAAAACAAAACACAGACTGCAATGTT TGTTTCTAAGTATTTTTGTATTGTGTACATTCTGTATATTTTTGTTGTAACATATTATTTGAGCACAGATTCCATTAAATATTTTTTTTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000269051_chr17_30615811_+_4709nt ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGA GCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGA GCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCT GCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGC AGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCA TGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAA TTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAG GGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTG TGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCT TTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCAC TGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGC TGCCGCCTCCCCCCTGAGGGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTC ATCACCAGCTCAGCTAGGCCGGGCAGACAAGGACAGAAGACTCTGGGCCACTGTAATGTTTGTGTTTAGATTTGGACACACAGTGGAGAC CCTTTTCTGAAAGGCATCTGGCGGAGGAGTTGATGTGGCTGCTGTCGTTTTTCTCGGCTGCTCTGATGACATCGGGCCAGGGTGAAGGTC TGGGGTGGGGTGTGAGAGTGGCCCTCCCTCACCTGGGCTGGGCTTCTTCCATGGGGCCAGGGGGTGCCCCCTCACTGCTGCGGATTGAGC AGCAGCTTCTTCCTCCTCCTCTACCCTCAGAGACCCTAAGAGACATGGGAAGGCTCGAAGGTTGTTGCGTCCAGGCATGGCCCCTCTCTA GCTCAGAAATAATTGCAGGCCATGTGGTGTCTCCTTGACACCTGCTGTGTCTGGGGCTCCAGTAAGAAGAGGGCCTACTGGACATGTCAG CTGTGACCTGGCTGAAACCAGGGTGCCCTCCTGGGCTGGTTGGTGTGCACCGGGGCATGATCTGTTGTGCCTGGGTTGGGCAGAGCAGGG AGCCTGTAGGCTCTAGGACCCCTCTTGTGCTGGGGGTACCCAGTGAGAGGGACCCATGCAGGGGGAATAAACTTCATTCCAAGTTCCACC CTGGAGAAGACAGACCCAGGACCAGCTTCAGACTTCTCCCTCCCTTTCTTCCAGGATATTGGCATCTCACACGGGTGCCCCAGCCTCCAT GCCCAGCCTTGTTTTAGGGTCTTTTTCTTTCCTTTTGCTGCCCTGACACTACTTTGTGCCTCTCTTTGGTTATGGAGACAGTGTTTTGAA ACATTCATGCGTGTGTGTGTGTGTGTGCGTATATGTGTGTATGTGATGGGAAAGGTAACTGAGGCACGACAGCGCCTGCAGAGAAGGCAT GGAGGATGCAGGGGGCCCATGTGGGCATCCGTGAGAGGTGGCAGACCGTGGTGTGCTGTGGTTGCTGAATGTCCTTGCTTTGACAAAGCC TGCCCCCTTCCTTCCCATCTCCTGTCCCTTCCACACCTGCCCCTGAGCATCACTGACCGGTGGCAGAATGGCCCTGCTGGAGGGAGAGCT CAAGCCCTCCAAGGATCCCTGGATGCTGAGGTTTGCCAGGTTCAGCTCTTGTTTCCGTCTGAGATGGCCTTCATATCCAAAAAGGTTCCA TCCTATCTCCCTTAGGAGAGAAAGAGCTTTGGGGGCGCAAGAGAGGCTGGGGTAGGAATGTTGAGGCCATGTGTCCATTTAAGTTAGGGG GACAGGAGGCTACAGGAAGAGGAATTCCAGTTTAGTTGGAAAACTTTGCCTCAGGAGAATTGTTGGGTGCATGGATGAACCTCAGAGGGA GGGCAGCCAGTAGCCTCGGAGGCTTGGATGCGGGAGAGAACATGGTGGTTATCAAATCCACCCCACCCCATTACACAGGTGAGAAAACAA GATGGAGGGAATGACCCTCCTAACAGGAGCTGGTGCAGGCCCCGAATGGAGGGCATGAGGATGACCTTTGACAAAAGATGACACTCCCTT TATCGTGCTCTTGGAATTCTCAACCACTGACAGCCCAGAAGAACAAAGAACGCCAGGCCTGGGAGGAGGCAGGGGGGCTGGGCGTGTCCA GAAACAGGGGCAGGAGTGTGGGAACGGTCTTCCTCCAGCCTGGTGCCCATCCTGGCCCTTGAGTGTAGCAGGGTCCAGGGTCAGTCAGGC CAGGCATTTGGGGTCTTGGGCCACAGTGGCTTCCCATCCTGGTGACTACATGTAAATGGGCTCACTCACTCACTGGCAGGCGAGGCCCAG CCATACCGCATCTTGGCCCACTGCTAAATAGATTGCCCTGGCCTCATCCACATATGTAGTTCCCTAGGTCCTGCTCCCCTGCACCAGTGC CATGCTGAGGGCCGCAGCCTGTGGCACTGTGGGCCCACGCCTTTGGCGGTGTTGCGTCAGCCTGGGGCGTCTTGTGTGTGCCCTGCCCAC CGTTCTCTGCCCTAGTGATAGAAAGATGTAGATGGAAGTCAGTGCCTCAGAGGAGGAGGCTCTGAGGCTGTGGAGCTGGGCTCAGGGAAG ACCAGGGGAGGATGCAGAAGGAGTCAGGACATTGCTGCCTCTGCCTGGGCTGCAGCCGCACTAAGCTGAGCGATGAGGTCCTTTCCTGGA GGGATGGAGAATCCCCTCCAGATTCCTGTCCTGGCCCCTGGGGATTCTGTGGTGTGGGTGGAATGAGCAGAGTGCCACCTCTGTCTGGTA TGACCTGGAGAGGGGGCTTCCTCTCTTAGGGGTGAGAAAGCATTGAACTAGAAGATTCTAGAAATCCCTCATAGAAGCACTCAGCTCCCT CGGGGACTCCCAGGGAAGCTTGTTACTGAGAAGGACAGTGGAGGCGGAATCGTGTCTCCCACCATGTTAAGTGTGTCCTCTGCTGCCAAG GACCCTCGTCTACACCTTAGACCACCAGCCCCAGCTGTTCTCTGTCAGCACACCCACCTCCATCCCCTCTCCCAACCATGACTTCCAAGC GGGGCCACAGGGTGGGGTCATAGGGTCACTTCACCTGACCCAGGCCTCTCCCCAGGTCAGGAGGCAGCTGTCTGGTCAGAGGGGTTCTCT TTGTGGCATCTGGCTTTCTCCTCAGCAGGTCCCACCACCCTCTCAGCAGCACTTCCCCATGGCCAAGGCTGGCCGTGTCCTCTGTGCCTC TTTCCTTGTCTGAGGTGGCTGCCAGCCCAGGGGGTGGTGTGTAAATCTTCAGGCTGGTGGAGGTAGGTTGGCCTTTTATCCACAGGATAC AGAAACTGAAAGCTGGGGAATCCCCAAACAGCAGCCATAGACTCACTGGCTCTCATTAAACGGGAGAGGAATCACAGAAACTGGGGAAGG GAAAACAAACCTTCAAAGGAGAAATTTCGCTTTAATGACACCATTCATCATTCGTTTTTTAATTAGGAAAAGCTCCCTAATGAGGCTCTT TTGCCAGCTAATAGGACTCTCGATTTCCATGAGAACCATTCTTGCCCAGAGGATTAGGGGAGCTGTTGCTCACCACACCAGGATCTTCCC CCAGCGTCCAATTTAATTTGCAAATACGTAATGCAGATTCCCTGGGTGCCGTGAAAGCCTTTCCTGGCATCATTCATGTTGCTCCCCGTG CTGGCTGGAAAGCACGGTTCTCCTCTGCCTTAAAAACAGTGCCCAACAGTGAACTGCCCCTCCGAGGACTTGAGTAAGTGGAAAAAACAA AACACAGACTGCAATGTTTGTTTCTAAGTATTTTTGTATTGTGTACATTCTGTATATTTTTGTTGTAACATATTATTTGAGCACAGATTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000538145_chr17_30615811_+_1411nt ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGA GCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGA GCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCT GCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGC AGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCA TGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAA TTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAG GGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTG TGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCT TTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCAC TGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGC TGCCGCCTCCCCCCTGAGGGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTC >In-frame_MED1_ENST00000300651_chr17_37604051_-_RHBDL3_ENST00000536287_chr17_30615811_+_4704nt ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGATGA GCAACAAGCGTTCCAACAGCTTCCGCCAAGCCATCCTGCAGGGCAACCGCAGGCTAAGCAGCAAGGCCCTGCTGGAGGAGAAGGGGCTGA GCCTCTCGCAGCGACTTATCCGCCATGTGGCCTATGAGACCCTGCCCCGGGAAATTGACCGCAAGTGGTACTATGACAGCTACACCTGCT GCCCCCCACCCTGGTTCATGATCACAGTCACGCTGCTGGAGGTTGCCTTTTTCCTCTACAATGGGGTGTCACTAGGTCAATTTGTACTGC AGGTAACTCATCCACGTTACTTGAAGAACTCCCTGGTTTACCACCCACAGCTGCGAGCACAGGTTTGGCGCTACCTGACATACATCTTCA TGCATGCAGGGATAGAACACCTGGGACTCAATGTGGTGCTGCAGCTGCTGGTGGGGGTGCCCCTGGAGATGGTGCATGGAGCCACCCGAA TTGGGCTTGTCTACGTGGCCGGTGTTGTGGCAGGGTCCTTGGCAGTGTCTGTGGCTGACATGACCGCTCCAGTCGTGGGCTCTTCTGGAG GGGTGTATGCTCTCGTCTCTGCCCATCTGGCCAACATTGTCATGAACTGGTCAGGCATGAAGTGCCAGTTCAAGCTGCTGCGGATGGCTG TGGCCCTTATCTGTATGAGCATGGAGTTTGGGCGGGCCGTGTGGCTCCGCTTCCACCCGTCGGCCTATCCCCCGTGCCCTCACCCAAGCT TTGTGGCGCACTTGGGTGGCGTGGCCGTGGGCATCACCCTGGGCGTGGTGGTCCTGAGGAACTACGAGCAGAGGCTCCAGGACCAGTCAC TGTGGTGGATTTTTGTGGCCATGTACACCGTCTTCGTGCTGTTCGCTGTCTTCTGGAACATCTTTGCCTACACCCTGCTGGACTTAAAGC TGCCGCCTCCCCCCTGAGGGCTGGAGGCCCAAGGTCGGGGAGGGGAGGGAAAAGCAGCACCCACAGGGAGCGCCTGCGAGGTTTCTTCTC ATCACCAGCTCAGCTAGGCCGGGCAGACAAGGACAGAAGACTCTGGGCCACTGTAATGTTTGTGTTTAGATTTGGACACACAGTGGAGAC CCTTTTCTGAAAGGCATCTGGCGGAGGAGTTGATGTGGCTGCTGTCGTTTTTCTCGGCTGCTCTGATGACATCGGGCCAGGGTGAAGGTC TGGGGTGGGGTGTGAGAGTGGCCCTCCCTCACCTGGGCTGGGCTTCTTCCATGGGGCCAGGGGGTGCCCCCTCACTGCTGCGGATTGAGC AGCAGCTTCTTCCTCCTCCTCTACCCTCAGAGACCCTAAGAGACATGGGAAGGCTCGAAGGTTGTTGCGTCCAGGCATGGCCCCTCTCTA GCTCAGAAATAATTGCAGGCCATGTGGTGTCTCCTTGACACCTGCTGTGTCTGGGGCTCCAGTAAGAAGAGGGCCTACTGGACATGTCAG CTGTGACCTGGCTGAAACCAGGGTGCCCTCCTGGGCTGGTTGGTGTGCACCGGGGCATGATCTGTTGTGCCTGGGTTGGGCAGAGCAGGG AGCCTGTAGGCTCTAGGACCCCTCTTGTGCTGGGGGTACCCAGTGAGAGGGACCCATGCAGGGGGAATAAACTTCATTCCAAGTTCCACC CTGGAGAAGACAGACCCAGGACCAGCTTCAGACTTCTCCCTCCCTTTCTTCCAGGATATTGGCATCTCACACGGGTGCCCCAGCCTCCAT GCCCAGCCTTGTTTTAGGGTCTTTTTCTTTCCTTTTGCTGCCCTGACACTACTTTGTGCCTCTCTTTGGTTATGGAGACAGTGTTTTGAA ACATTCATGCGTGTGTGTGTGTGTGTGCGTATATGTGTGTATGTGATGGGAAAGGTAACTGAGGCACGACAGCGCCTGCAGAGAAGGCAT GGAGGATGCAGGGGGCCCATGTGGGCATCCGTGAGAGGTGGCAGACCGTGGTGTGCTGTGGTTGCTGAATGTCCTTGCTTTGACAAAGCC TGCCCCCTTCCTTCCCATCTCCTGTCCCTTCCACACCTGCCCCTGAGCATCACTGACCGGTGGCAGAATGGCCCTGCTGGAGGGAGAGCT CAAGCCCTCCAAGGATCCCTGGATGCTGAGGTTTGCCAGGTTCAGCTCTTGTTTCCGTCTGAGATGGCCTTCATATCCAAAAAGGTTCCA TCCTATCTCCCTTAGGAGAGAAAGAGCTTTGGGGGCGCAAGAGAGGCTGGGGTAGGAATGTTGAGGCCATGTGTCCATTTAAGTTAGGGG GACAGGAGGCTACAGGAAGAGGAATTCCAGTTTAGTTGGAAAACTTTGCCTCAGGAGAATTGTTGGGTGCATGGATGAACCTCAGAGGGA GGGCAGCCAGTAGCCTCGGAGGCTTGGATGCGGGAGAGAACATGGTGGTTATCAAATCCACCCCACCCCATTACACAGGTGAGAAAACAA GATGGAGGGAATGACCCTCCTAACAGGAGCTGGTGCAGGCCCCGAATGGAGGGCATGAGGATGACCTTTGACAAAAGATGACACTCCCTT TATCGTGCTCTTGGAATTCTCAACCACTGACAGCCCAGAAGAACAAAGAACGCCAGGCCTGGGAGGAGGCAGGGGGGCTGGGCGTGTCCA GAAACAGGGGCAGGAGTGTGGGAACGGTCTTCCTCCAGCCTGGTGCCCATCCTGGCCCTTGAGTGTAGCAGGGTCCAGGGTCAGTCAGGC CAGGCATTTGGGGTCTTGGGCCACAGTGGCTTCCCATCCTGGTGACTACATGTAAATGGGCTCACTCACTCACTGGCAGGCGAGGCCCAG CCATACCGCATCTTGGCCCACTGCTAAATAGATTGCCCTGGCCTCATCCACATATGTAGTTCCCTAGGTCCTGCTCCCCTGCACCAGTGC CATGCTGAGGGCCGCAGCCTGTGGCACTGTGGGCCCACGCCTTTGGCGGTGTTGCGTCAGCCTGGGGCGTCTTGTGTGTGCCCTGCCCAC CGTTCTCTGCCCTAGTGATAGAAAGATGTAGATGGAAGTCAGTGCCTCAGAGGAGGAGGCTCTGAGGCTGTGGAGCTGGGCTCAGGGAAG ACCAGGGGAGGATGCAGAAGGAGTCAGGACATTGCTGCCTCTGCCTGGGCTGCAGCCGCACTAAGCTGAGCGATGAGGTCCTTTCCTGGA GGGATGGAGAATCCCCTCCAGATTCCTGTCCTGGCCCCTGGGGATTCTGTGGTGTGGGTGGAATGAGCAGAGTGCCACCTCTGTCTGGTA TGACCTGGAGAGGGGGCTTCCTCTCTTAGGGGTGAGAAAGCATTGAACTAGAAGATTCTAGAAATCCCTCATAGAAGCACTCAGCTCCCT CGGGGACTCCCAGGGAAGCTTGTTACTGAGAAGGACAGTGGAGGCGGAATCGTGTCTCCCACCATGTTAAGTGTGTCCTCTGCTGCCAAG GACCCTCGTCTACACCTTAGACCACCAGCCCCAGCTGTTCTCTGTCAGCACACCCACCTCCATCCCCTCTCCCAACCATGACTTCCAAGC GGGGCCACAGGGTGGGGTCATAGGGTCACTTCACCTGACCCAGGCCTCTCCCCAGGTCAGGAGGCAGCTGTCTGGTCAGAGGGGTTCTCT TTGTGGCATCTGGCTTTCTCCTCAGCAGGTCCCACCACCCTCTCAGCAGCACTTCCCCATGGCCAAGGCTGGCCGTGTCCTCTGTGCCTC TTTCCTTGTCTGAGGTGGCTGCCAGCCCAGGGGGTGGTGTGTAAATCTTCAGGCTGGTGGAGGTAGGTTGGCCTTTTATCCACAGGATAC AGAAACTGAAAGCTGGGGAATCCCCAAACAGCAGCCATAGACTCACTGGCTCTCATTAAACGGGAGAGGAATCACAGAAACTGGGGAAGG GAAAACAAACCTTCAAAGGAGAAATTTCGCTTTAATGACACCATTCATCATTCGTTTTTTAATTAGGAAAAGCTCCCTAATGAGGCTCTT TTGCCAGCTAATAGGACTCTCGATTTCCATGAGAACCATTCTTGCCCAGAGGATTAGGGGAGCTGTTGCTCACCACACCAGGATCTTCCC CCAGCGTCCAATTTAATTTGCAAATACGTAATGCAGATTCCCTGGGTGCCGTGAAAGCCTTTCCTGGCATCATTCATGTTGCTCCCCGTG CTGGCTGGAAAGCACGGTTCTCCTCTGCCTTAAAAACAGTGCCCAACAGTGAACTGCCCCTCCGAGGACTTGAGTAAGTGGAAAAAACAA AACACAGACTGCAATGTTTGTTTCTAAGTATTTTTGTATTGTGTACATTCTGTATATTTTTGTTGTAACATATTATTTGAGCACAGATTC |
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FusionGenePPI for MED1_RHBDL3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MED1 | MED10, MED9, MED29, MED19, MED28, MED26, PPARGC1A, NR3C1, YWHAQ, TGS1, TP53, CDK8, VDR, MED1, HNF4A, THRA, THRAP3, MED24, AR, ESR1, ESR2, MED13, MED6, MED16, MED17, MED20, MED14, MED12, MED23, MED27, MED4, MED7, MED8, MED30, MED22, MED31, MED15, MED18, MED11, MED25, POLR2A, MED21, POLR2F, GABPA, GATA1, ATM, POU1F1, GATA2, PARP1, RXRA, TRRAP, PPARG, RARA, SREBF1, KAT2A, SUPT3H, SUPT7L, MYC, CCNC, CDK19, POLR2E, CDK9, ZC3H13, TRIP4, OBFC1, QKI, TADA2A, TRA, NR1H2, KIF1A, BRD4, CTDP1, NCOA6, ELAVL1, MDM2, ZNF281, ZNF326, RALY, SETD7, FBXW7, MED13L, EPAS1, EZH2, BAG3, GJB5, PIN1, POLL, NR1I3, TCL1B, HNRNPC, NTRK1, POLR2G, EMC2, SMEK1, MED12L, RPAP2, POLR2D, BIRC5, PLK1, SPAG5 | RHBDL3 | PTCRA, EIF2AK3, BIK, VCP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 16_590 | 44 | 1582 | ESR1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 656_1066 | 44 | 1582 | ESR1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 16_590 | 44 | 557 | ESR1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 656_1066 | 44 | 557 | ESR1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 681_715 | 44 | 1582 | GATA1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 681_715 | 44 | 557 | GATA1 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 622_701 | 44 | 1582 | PPARGC1A and THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 622_701 | 44 | 557 | PPARGC1A and THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 108_212 | 44 | 1582 | the Mediator complex |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 215_390 | 44 | 1582 | the Mediator complex |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 108_212 | 44 | 557 | the Mediator complex |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 215_390 | 44 | 557 | the Mediator complex |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 1_670 | 44 | 1582 | the Mediator complex and THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 1_670 | 44 | 557 | the Mediator complex and THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 405_644 | 44 | 1582 | THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 405_644 | 44 | 557 | THRA |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 1249_1421 | 44 | 1582 | TP53 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 1249_1421 | 44 | 557 | TP53 |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000300651 | - | 2 | 17 | 542_789 | 44 | 1582 | VDR |
| Hgene | MED1 | chr17:37604051 | chr17:30615811 | ENST00000394287 | - | 2 | 18 | 542_789 | 44 | 557 | VDR |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MED1_RHBDL3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MED1_RHBDL3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MED1 | C0014175 | Endometriosis | 1 | CTD_human |
| Hgene | MED1 | C2239176 | Liver carcinoma | 1 | CTD_human |
| Hgene | MED1 | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
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