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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 21498

FusionGeneSummary for MED1_ABCC3

check button Fusion gene summary
Fusion gene informationFusion gene name: MED1_ABCC3
Fusion gene ID: 21498
HgeneTgene
Gene symbol

MED1

ABCC3

Gene ID

8930

8714

Gene namemethyl-CpG binding domain 4, DNA glycosylaseATP binding cassette subfamily C member 3
SynonymsMED1ABC31|EST90757|MLP2|MOAT-D|MRP3|cMOAT2
Cytomap

3q21.3

17q21.33

Type of geneprotein-codingprotein-coding
Descriptionmethyl-CpG-binding domain protein 43,N(4)-ethenocytosine glycosylaseG/5-fluorouracil mismatch glycosylase with biphasic kineticsG/T mismatch glycosylaseG/U mismatch glycosylasemethyl-CpG binding domain protein 4methyl-CpG-binding endonuclease 1methcanalicular multispecific organic anion transporter 2ATP-binding cassette sub-family C member 3ATP-binding cassette, sub-family C (CFTR/MRP), member 3canicular multispecific organic anion transportermulti-specific organic anion transporter Dmultidrug
Modification date2018052320180523
UniProtAcc

Q15648

O15438

Ensembl transtripts involved in fusion geneENST00000394287, ENST00000300651, 
ENST00000285238, ENST00000515707, 
ENST00000427699, ENST00000510891, 
Fusion gene scores* DoF score25 X 11 X 9=24757 X 8 X 3=168
# samples 2511
** MAII scorelog2(25/2475*10)=-3.30742852519225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/168*10)=-0.610957709254101
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MED1 [Title/Abstract] AND ABCC3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-BH-A0AW-01AMED1chr17

37604051

-ABCC3chr17

48733193

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000394287ENST00000285238MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000394287ENST00000515707MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000394287ENST00000427699MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000394287ENST00000510891MED1chr17

37604051

-ABCC3chr17

48733193

+
In-frameENST00000300651ENST00000285238MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000300651ENST00000515707MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000300651ENST00000427699MED1chr17

37604051

-ABCC3chr17

48733193

+
5CDS-intronENST00000300651ENST00000510891MED1chr17

37604051

-ABCC3chr17

48733193

+

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FusionProtFeatures for MED1_ABCC3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MED1

Q15648

ABCC3

O15438

Component of the Mediator complex, a coactivatorinvolved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge toconvey information from gene-specific regulatory proteins to thebasal RNA polymerase II transcription machinery. Mediator isrecruited to promoters by direct interactions with regulatoryproteins and serves as a scaffold for the assembly of a functionalpreinitiation complex with RNA polymerase II and the generaltranscription factors (PubMed:10406464, PubMed:11867769,PubMed:12037571, PubMed:12218053, PubMed:12556447,PubMed:14636573, PubMed:15340084, PubMed:15471764,PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as acoactivator for GATA1-mediated transcriptional activation duringerythroid differentiation of K562 erythroleukemia cells(PubMed:24245781). {ECO:0000269|PubMed:10406464,ECO:0000269|PubMed:11867769, ECO:0000269|PubMed:12037571,ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:12556447,ECO:0000269|PubMed:14636573, ECO:0000269|PubMed:15340084,ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:15989967,ECO:0000269|PubMed:16574658, ECO:0000269|PubMed:24245781,ECO:0000269|PubMed:9653119}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311291_1523151528DomainABC transporter 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031311_594151528DomainABC transmembrane type-1 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031629_851151528DomainABC transporter 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031971_1252151528DomainABC transmembrane type-1 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121291_152315573DomainABC transporter 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012311_59415573DomainABC transmembrane type-1 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012629_85115573DomainABC transporter 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012971_125215573DomainABC transmembrane type-1 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311323_1330151528Nucleotide bindingATP 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031661_668151528Nucleotide bindingATP 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121323_133015573Nucleotide bindingATP 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012661_66815573Nucleotide bindingATP 1
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311043_1085151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311107_1107151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311129_1199151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031121_132151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311221_1222151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311244_1527151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031154_171151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031193_302151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031324_349151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031371_426151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031448_450151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031472_533151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+03154_73151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031555_576151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031598_963151528Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+03195_99151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031985_1021151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121043_108515573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121107_110715573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121129_119915573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012121_13215573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121221_122215573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121244_152715573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012154_17115573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012193_30215573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012324_34915573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012371_42615573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012448_45015573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012472_53315573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+01254_7315573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012555_57615573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012598_96315573Topological domainCytoplasmic
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+01295_9915573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012985_102115573Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031100_120151528TransmembraneHelical%3B Name%3D3
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311022_1042151528TransmembraneHelical%3B Name%3D13
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311086_1106151528TransmembraneHelical%3B Name%3D14
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311108_1128151528TransmembraneHelical%3B Name%3D15
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311200_1220151528TransmembraneHelical%3B Name%3D16
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311223_1243151528TransmembraneHelical%3B Name%3D17
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031133_153151528TransmembraneHelical%3B Name%3D4
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031172_192151528TransmembraneHelical%3B Name%3D5
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031303_323151528TransmembraneHelical%3B Name%3D6
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+03133_53151528TransmembraneHelical%3B Name%3D1
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031350_370151528TransmembraneHelical%3B Name%3D7
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031427_447151528TransmembraneHelical%3B Name%3D8
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031451_471151528TransmembraneHelical%3B Name%3D9
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031534_554151528TransmembraneHelical%3B Name%3D10
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031577_597151528TransmembraneHelical%3B Name%3D11
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+03174_94151528TransmembraneHelical%3B Name%3D2
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+031964_984151528TransmembraneHelical%3B Name%3D12
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012100_12015573TransmembraneHelical%3B Name%3D3
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121022_104215573TransmembraneHelical%3B Name%3D13
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121086_110615573TransmembraneHelical%3B Name%3D14
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121108_112815573TransmembraneHelical%3B Name%3D15
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121200_122015573TransmembraneHelical%3B Name%3D16
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121223_124315573TransmembraneHelical%3B Name%3D17
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012133_15315573TransmembraneHelical%3B Name%3D4
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012172_19215573TransmembraneHelical%3B Name%3D5
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012303_32315573TransmembraneHelical%3B Name%3D6
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+01233_5315573TransmembraneHelical%3B Name%3D1
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012350_37015573TransmembraneHelical%3B Name%3D7
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012427_44715573TransmembraneHelical%3B Name%3D8
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012451_47115573TransmembraneHelical%3B Name%3D9
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012534_55415573TransmembraneHelical%3B Name%3D10
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012577_59715573TransmembraneHelical%3B Name%3D11
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+01274_9415573TransmembraneHelical%3B Name%3D2
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+012964_98415573TransmembraneHelical%3B Name%3D12

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-2171078_1482441582Compositional biasNote=Ser-rich
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-2171496_1529441582Compositional biasNote=Lys-rich
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-2181078_148244557Compositional biasNote=Ser-rich
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-2181496_152944557Compositional biasNote=Lys-rich
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217604_608441582MotifNote=LXXLL motif 1
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217645_649441582MotifNote=LXXLL motif 2
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218604_60844557MotifNote=LXXLL motif 1
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218645_64944557MotifNote=LXXLL motif 2
TgeneABCC3chr17:37604051chr17:48733193ENST00000285238+0311_32151528Topological domainExtracellular
TgeneABCC3chr17:37604051chr17:48733193ENST00000427699+0121_3215573Topological domainExtracellular


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FusionGeneSequence for MED1_ABCC3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MED1_ENST00000394287_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_1557aa
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCR
GYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVP
FRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLW
SLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQL
LSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFM
DLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFL
KQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKR
IQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSV
AYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAV
DSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGA
EDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWD
YAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHN
KIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLES
VSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVS
YSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGI
VGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQ
PAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVV

>In-frame_MED1_ENST00000300651_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_1557aa
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCR
GYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVP
FRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLW
SLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQL
LSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFM
DLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFL
KQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKR
IQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSV
AYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAV
DSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGA
EDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWD
YAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHN
KIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLES
VSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVS
YSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGI
VGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQ
PAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVV


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MED1_ENST00000394287_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_4671nt
ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT
AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGACTCCAACCTGTCTGTGCACACAGAAAACCCGGACCTCACTCCCTGC
TTCCAGAACTCCCTGCTGGCCTGGGTGCCCTGCATCTACCTGTGGGTCGCCCTGCCCTGCTACTTGCTCTACCTGCGGCACCATTGTCGT
GGCTACATCATCCTCTCCCACCTGTCCAAGCTCAAGATGGTCCTGGGTGTCCTGCTGTGGTGCGTCTCCTGGGCGGACCTTTTTTACTCC
TTCCATGGCCTGGTCCATGGCCGGGCCCCTGCCCCTGTTTTCTTTGTCACCCCCTTGGTGGTGGGGGTCACCATGCTGCTGGCCACCCTG
CTGATACAGTATGAGCGGCTGCAGGGCGTACAGTCTTCGGGGGTCCTCATTATCTTCTGGTTCCTGTGTGTGGTCTGCGCCATCGTCCCA
TTCCGCTCCAAGATCCTTTTAGCCAAGGCAGAGGGTGAGATCTCAGACCCCTTCCGCTTCACCACCTTCTACATCCACTTTGCCCTGGTA
CTCTCTGCCCTCATCTTGGCCTGCTTCAGGGAGAAACCTCCATTTTTCTCCGCAAAGAATGTCGACCCTAACCCCTACCCTGAGACCAGC
GCTGGCTTTCTCTCCCGCCTGTTTTTCTGGTGGTTCACAAAGATGGCCATCTATGGCTACCGGCATCCCCTGGAGGAGAAGGACCTCTGG
TCCCTAAAGGAAGAGGACAGATCCCAGATGGTGGTGCAGCAGCTGCTGGAGGCATGGAGGAAGCAGGAAAAGCAGACGGCACGACACAAG
GCTTCAGCAGCACCTGGGAAAAATGCCTCCGGCGAGGACGAGGTGCTGCTGGGTGCCCGGCCCAGGCCCCGGAAGCCCTCCTTCCTGAAG
GCCCTGCTGGCCACCTTCGGCTCCAGCTTCCTCATCAGTGCCTGCTTCAAGCTTATCCAGGACCTGCTCTCCTTCATCAATCCACAGCTG
CTCAGCATCCTGATCAGGTTTATCTCCAACCCCATGGCCCCCTCCTGGTGGGGCTTCCTGGTGGCTGGGCTGATGTTCCTGTGCTCCATG
ATGCAGTCGCTGATCTTACAACACTATTACCACTACATCTTTGTGACTGGGGTGAAGTTTCGTACTGGGATCATGGGTGTCATCTACAGG
AAGGCTCTGGTTATCACCAACTCAGTCAAACGTGCGTCCACTGTGGGGGAAATTGTCAACCTCATGTCAGTGGATGCCCAGCGCTTCATG
GACCTTGCCCCCTTCCTCAATCTGCTGTGGTCAGCACCCCTGCAGATCATCCTGGCGATCTACTTCCTCTGGCAGAACCTAGGTCCCTCT
GTCCTGGCTGGAGTCGCTTTCATGGTCTTGCTGATTCCACTCAACGGAGCTGTGGCCGTGAAGATGCGCGCCTTCCAGGTAAAGCAAATG
AAATTGAAGGACTCGCGCATCAAGCTGATGAGTGAGATCCTGAACGGCATCAAGGTGCTGAAGCTGTACGCCTGGGAGCCCAGCTTCCTG
AAGCAGGTGGAGGGCATCAGGCAGGGTGAGCTCCAGCTGCTGCGCACGGCGGCCTACCTCCACACCACAACCACCTTCACCTGGATGTGC
AGCCCCTTCCTGGTGACCCTGATCACCCTCTGGGTGTACGTGTACGTGGACCCAAACAATGTGCTGGACGCCGAGAAGGCCTTTGTGTCT
GTGTCCTTGTTTAATATCTTAAGACTTCCCCTCAACATGCTGCCCCAGTTAATCAGCAACCTGACTCAGGCCAGTGTGTCTCTGAAACGG
ATCCAGCAATTCCTGAGCCAAGAGGAACTTGACCCCCAGAGTGTGGAAAGAAAGACCATCTCCCCAGGCTATGCCATCACCATACACAGT
GGCACCTTCACCTGGGCCCAGGACCTGCCCCCCACTCTGCACAGCCTAGACATCCAGGTCCCGAAAGGGGCACTGGTGGCCGTGGTGGGG
CCTGTGGGCTGTGGGAAGTCCTCCCTGGTGTCTGCCCTGCTGGGAGAGATGGAGAAGCTAGAAGGCAAAGTGCACATGAAGGGCTCCGTG
GCCTATGTGCCCCAGCAGGCATGGATCCAGAACTGCACTCTTCAGGAAAACGTGCTTTTCGGCAAAGCCCTGAACCCCAAGCGCTACCAG
CAGACTCTGGAGGCCTGTGCCTTGCTAGCTGACCTGGAGATGCTGCCTGGTGGGGATCAGACAGAGATTGGAGAGAAGGGCATTAACCTG
TCTGGGGGCCAGCGGCAGCGGGTCAGTCTGGCTCGAGCTGTTTACAGTGATGCCGATATTTTCTTGCTGGATGACCCACTGTCCGCGGTG
GACTCTCATGTGGCCAAGCACATCTTTGACCACGTCATCGGGCCAGAAGGCGTGCTGGCAGGCAAGACGCGAGTGCTGGTGACGCACGGC
ATTAGCTTCCTGCCCCAGACAGACTTCATCATTGTGCTAGCTGATGGACAGGTGTCTGAGATGGGCCCGTACCCAGCCCTGCTGCAGCGC
AACGGCTCCTTTGCCAACTTTCTCTGCAACTATGCCCCCGATGAGGACCAAGGGCACCTGGAGGACAGCTGGACCGCGTTGGAAGGTGCA
GAGGATAAGGAGGCACTGCTGATTGAAGACACACTCAGCAACCACACGGATCTGACAGACAATGATCCAGTCACCTATGTGGTCCAGAAG
CAGTTTATGAGACAGCTGAGTGCCCTGTCCTCAGATGGGGAGGGACAGGGTCGGCCTGTACCCCGGAGGCACCTGGGTCCATCAGAGAAG
GTGCAGGTGACAGAGGCGAAGGCAGATGGGGCACTGACCCAGGAGGAGAAAGCAGCCATTGGCACTGTGGAGCTCAGTGTGTTCTGGGAT
TATGCCAAGGCCGTGGGGCTCTGTACCACGCTGGCCATCTGTCTCCTGTATGTGGGTCAAAGTGCGGCTGCCATTGGAGCCAATGTGTGG
CTCAGTGCCTGGACAAATGATGCCATGGCAGACAGTAGACAGAACAACACTTCCCTGAGGCTGGGCGTCTATGCTGCTTTAGGAATTCTG
CAAGGGTTCTTGGTGATGCTGGCAGCCATGGCCATGGCAGCGGGTGGCATCCAGGCTGCCCGTGTGTTGCACCAGGCACTGCTGCACAAC
AAGATACGCTCGCCACAGTCCTTCTTTGACACCACACCATCAGGCCGCATCCTGAACTGCTTCTCCAAGGACATCTATGTCGTTGATGAG
GTTCTGGCCCCTGTCATCCTCATGCTGCTCAATTCCTTCTTCAACGCCATCTCCACTCTTGTGGTCATCATGGCCAGCACGCCGCTCTTC
ACTGTGGTCATCCTGCCCCTGGCTGTGCTCTACACCTTAGTGCAGCGCTTCTATGCAGCCACATCACGGCAACTGAAGCGGCTGGAATCA
GTCAGCCGCTCACCTATCTACTCCCACTTTTCGGAGACAGTGACTGGTGCCAGTGTCATCCGGGCCTACAACCGCAGCCGGGATTTTGAG
ATCATCAGTGATACTAAGGTGGATGCCAACCAGAGAAGCTGCTACCCCTACATCATCTCCAACCGGTGGCTGAGCATCGGAGTGGAGTTC
GTGGGGAACTGCGTGGTGCTCTTTGCTGCACTATTTGCCGTCATCGGGAGGAGCAGCCTGAACCCGGGGCTGGTGGGCCTTTCTGTGTCC
TACTCCTTGCAGGTGACATTTGCTCTGAACTGGATGATACGAATGATGTCAGATTTGGAATCTAACATCGTGGCTGTGGAGAGGGTCAAG
GAGTACTCCAAGACAGAGACAGAGGCGCCCTGGGTGGTGGAAGGCAGCCGCCCTCCCGAAGGTTGGCCCCCACGTGGGGAGGTGGAGTTC
CGGAATTATTCTGTGCGCTACCGGCCGGGCCTAGACCTGGTGCTGAGAGACCTGAGTCTGCATGTGCACGGTGGCGAGAAGGTGGGGATC
GTGGGCCGCACTGGGGCTGGCAAGTCTTCCATGACCCTTTGCCTGTTCCGCATCCTGGAGGCGGCAAAGGGTGAAATCCGCATTGATGGC
CTCAATGTGGCAGACATCGGCCTCCATGACCTGCGCTCTCAGCTGACCATCATCCCGCAGGACCCCATCCTGTTCTCGGGGACCCTGCGC
ATGAACCTGGACCCCTTCGGCAGCTACTCAGAGGAGGACATTTGGTGGGCTTTGGAGCTGTCCCACCTGCACACGTTTGTGAGCTCCCAG
CCGGCAGGCCTGGACTTCCAGTGCTCAGAGGGCGGGGAGAATCTCAGCGTGGGCCAGAGGCAGCTCGTGTGCCTGGCCCGAGCCCTGCTC
CGCAAGAGCCGCATCCTGGTTTTAGACGAGGCCACAGCTGCCATCGACCTGGAGACTGACAACCTCATCCAGGCTACCATCCGCACCCAG
TTTGATACCTGCACTGTCCTGACCATCGCACACCGGCTTAACACTATCATGGACTACACCAGGGTCCTGGTCCTGGACAAAGGAGTAGTA

>In-frame_MED1_ENST00000300651_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_4671nt
ATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAAT
AGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGACTCCAACCTGTCTGTGCACACAGAAAACCCGGACCTCACTCCCTGC
TTCCAGAACTCCCTGCTGGCCTGGGTGCCCTGCATCTACCTGTGGGTCGCCCTGCCCTGCTACTTGCTCTACCTGCGGCACCATTGTCGT
GGCTACATCATCCTCTCCCACCTGTCCAAGCTCAAGATGGTCCTGGGTGTCCTGCTGTGGTGCGTCTCCTGGGCGGACCTTTTTTACTCC
TTCCATGGCCTGGTCCATGGCCGGGCCCCTGCCCCTGTTTTCTTTGTCACCCCCTTGGTGGTGGGGGTCACCATGCTGCTGGCCACCCTG
CTGATACAGTATGAGCGGCTGCAGGGCGTACAGTCTTCGGGGGTCCTCATTATCTTCTGGTTCCTGTGTGTGGTCTGCGCCATCGTCCCA
TTCCGCTCCAAGATCCTTTTAGCCAAGGCAGAGGGTGAGATCTCAGACCCCTTCCGCTTCACCACCTTCTACATCCACTTTGCCCTGGTA
CTCTCTGCCCTCATCTTGGCCTGCTTCAGGGAGAAACCTCCATTTTTCTCCGCAAAGAATGTCGACCCTAACCCCTACCCTGAGACCAGC
GCTGGCTTTCTCTCCCGCCTGTTTTTCTGGTGGTTCACAAAGATGGCCATCTATGGCTACCGGCATCCCCTGGAGGAGAAGGACCTCTGG
TCCCTAAAGGAAGAGGACAGATCCCAGATGGTGGTGCAGCAGCTGCTGGAGGCATGGAGGAAGCAGGAAAAGCAGACGGCACGACACAAG
GCTTCAGCAGCACCTGGGAAAAATGCCTCCGGCGAGGACGAGGTGCTGCTGGGTGCCCGGCCCAGGCCCCGGAAGCCCTCCTTCCTGAAG
GCCCTGCTGGCCACCTTCGGCTCCAGCTTCCTCATCAGTGCCTGCTTCAAGCTTATCCAGGACCTGCTCTCCTTCATCAATCCACAGCTG
CTCAGCATCCTGATCAGGTTTATCTCCAACCCCATGGCCCCCTCCTGGTGGGGCTTCCTGGTGGCTGGGCTGATGTTCCTGTGCTCCATG
ATGCAGTCGCTGATCTTACAACACTATTACCACTACATCTTTGTGACTGGGGTGAAGTTTCGTACTGGGATCATGGGTGTCATCTACAGG
AAGGCTCTGGTTATCACCAACTCAGTCAAACGTGCGTCCACTGTGGGGGAAATTGTCAACCTCATGTCAGTGGATGCCCAGCGCTTCATG
GACCTTGCCCCCTTCCTCAATCTGCTGTGGTCAGCACCCCTGCAGATCATCCTGGCGATCTACTTCCTCTGGCAGAACCTAGGTCCCTCT
GTCCTGGCTGGAGTCGCTTTCATGGTCTTGCTGATTCCACTCAACGGAGCTGTGGCCGTGAAGATGCGCGCCTTCCAGGTAAAGCAAATG
AAATTGAAGGACTCGCGCATCAAGCTGATGAGTGAGATCCTGAACGGCATCAAGGTGCTGAAGCTGTACGCCTGGGAGCCCAGCTTCCTG
AAGCAGGTGGAGGGCATCAGGCAGGGTGAGCTCCAGCTGCTGCGCACGGCGGCCTACCTCCACACCACAACCACCTTCACCTGGATGTGC
AGCCCCTTCCTGGTGACCCTGATCACCCTCTGGGTGTACGTGTACGTGGACCCAAACAATGTGCTGGACGCCGAGAAGGCCTTTGTGTCT
GTGTCCTTGTTTAATATCTTAAGACTTCCCCTCAACATGCTGCCCCAGTTAATCAGCAACCTGACTCAGGCCAGTGTGTCTCTGAAACGG
ATCCAGCAATTCCTGAGCCAAGAGGAACTTGACCCCCAGAGTGTGGAAAGAAAGACCATCTCCCCAGGCTATGCCATCACCATACACAGT
GGCACCTTCACCTGGGCCCAGGACCTGCCCCCCACTCTGCACAGCCTAGACATCCAGGTCCCGAAAGGGGCACTGGTGGCCGTGGTGGGG
CCTGTGGGCTGTGGGAAGTCCTCCCTGGTGTCTGCCCTGCTGGGAGAGATGGAGAAGCTAGAAGGCAAAGTGCACATGAAGGGCTCCGTG
GCCTATGTGCCCCAGCAGGCATGGATCCAGAACTGCACTCTTCAGGAAAACGTGCTTTTCGGCAAAGCCCTGAACCCCAAGCGCTACCAG
CAGACTCTGGAGGCCTGTGCCTTGCTAGCTGACCTGGAGATGCTGCCTGGTGGGGATCAGACAGAGATTGGAGAGAAGGGCATTAACCTG
TCTGGGGGCCAGCGGCAGCGGGTCAGTCTGGCTCGAGCTGTTTACAGTGATGCCGATATTTTCTTGCTGGATGACCCACTGTCCGCGGTG
GACTCTCATGTGGCCAAGCACATCTTTGACCACGTCATCGGGCCAGAAGGCGTGCTGGCAGGCAAGACGCGAGTGCTGGTGACGCACGGC
ATTAGCTTCCTGCCCCAGACAGACTTCATCATTGTGCTAGCTGATGGACAGGTGTCTGAGATGGGCCCGTACCCAGCCCTGCTGCAGCGC
AACGGCTCCTTTGCCAACTTTCTCTGCAACTATGCCCCCGATGAGGACCAAGGGCACCTGGAGGACAGCTGGACCGCGTTGGAAGGTGCA
GAGGATAAGGAGGCACTGCTGATTGAAGACACACTCAGCAACCACACGGATCTGACAGACAATGATCCAGTCACCTATGTGGTCCAGAAG
CAGTTTATGAGACAGCTGAGTGCCCTGTCCTCAGATGGGGAGGGACAGGGTCGGCCTGTACCCCGGAGGCACCTGGGTCCATCAGAGAAG
GTGCAGGTGACAGAGGCGAAGGCAGATGGGGCACTGACCCAGGAGGAGAAAGCAGCCATTGGCACTGTGGAGCTCAGTGTGTTCTGGGAT
TATGCCAAGGCCGTGGGGCTCTGTACCACGCTGGCCATCTGTCTCCTGTATGTGGGTCAAAGTGCGGCTGCCATTGGAGCCAATGTGTGG
CTCAGTGCCTGGACAAATGATGCCATGGCAGACAGTAGACAGAACAACACTTCCCTGAGGCTGGGCGTCTATGCTGCTTTAGGAATTCTG
CAAGGGTTCTTGGTGATGCTGGCAGCCATGGCCATGGCAGCGGGTGGCATCCAGGCTGCCCGTGTGTTGCACCAGGCACTGCTGCACAAC
AAGATACGCTCGCCACAGTCCTTCTTTGACACCACACCATCAGGCCGCATCCTGAACTGCTTCTCCAAGGACATCTATGTCGTTGATGAG
GTTCTGGCCCCTGTCATCCTCATGCTGCTCAATTCCTTCTTCAACGCCATCTCCACTCTTGTGGTCATCATGGCCAGCACGCCGCTCTTC
ACTGTGGTCATCCTGCCCCTGGCTGTGCTCTACACCTTAGTGCAGCGCTTCTATGCAGCCACATCACGGCAACTGAAGCGGCTGGAATCA
GTCAGCCGCTCACCTATCTACTCCCACTTTTCGGAGACAGTGACTGGTGCCAGTGTCATCCGGGCCTACAACCGCAGCCGGGATTTTGAG
ATCATCAGTGATACTAAGGTGGATGCCAACCAGAGAAGCTGCTACCCCTACATCATCTCCAACCGGTGGCTGAGCATCGGAGTGGAGTTC
GTGGGGAACTGCGTGGTGCTCTTTGCTGCACTATTTGCCGTCATCGGGAGGAGCAGCCTGAACCCGGGGCTGGTGGGCCTTTCTGTGTCC
TACTCCTTGCAGGTGACATTTGCTCTGAACTGGATGATACGAATGATGTCAGATTTGGAATCTAACATCGTGGCTGTGGAGAGGGTCAAG
GAGTACTCCAAGACAGAGACAGAGGCGCCCTGGGTGGTGGAAGGCAGCCGCCCTCCCGAAGGTTGGCCCCCACGTGGGGAGGTGGAGTTC
CGGAATTATTCTGTGCGCTACCGGCCGGGCCTAGACCTGGTGCTGAGAGACCTGAGTCTGCATGTGCACGGTGGCGAGAAGGTGGGGATC
GTGGGCCGCACTGGGGCTGGCAAGTCTTCCATGACCCTTTGCCTGTTCCGCATCCTGGAGGCGGCAAAGGGTGAAATCCGCATTGATGGC
CTCAATGTGGCAGACATCGGCCTCCATGACCTGCGCTCTCAGCTGACCATCATCCCGCAGGACCCCATCCTGTTCTCGGGGACCCTGCGC
ATGAACCTGGACCCCTTCGGCAGCTACTCAGAGGAGGACATTTGGTGGGCTTTGGAGCTGTCCCACCTGCACACGTTTGTGAGCTCCCAG
CCGGCAGGCCTGGACTTCCAGTGCTCAGAGGGCGGGGAGAATCTCAGCGTGGGCCAGAGGCAGCTCGTGTGCCTGGCCCGAGCCCTGCTC
CGCAAGAGCCGCATCCTGGTTTTAGACGAGGCCACAGCTGCCATCGACCTGGAGACTGACAACCTCATCCAGGCTACCATCCGCACCCAG
TTTGATACCTGCACTGTCCTGACCATCGCACACCGGCTTAACACTATCATGGACTACACCAGGGTCCTGGTCCTGGACAAAGGAGTAGTA


* Fusion transcript sequences (Full-length transcript).
>In-frame_MED1_ENST00000394287_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_5929nt
TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA
GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC
GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC
GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGACTCCAACCTGTCTGTGCACA
CAGAAAACCCGGACCTCACTCCCTGCTTCCAGAACTCCCTGCTGGCCTGGGTGCCCTGCATCTACCTGTGGGTCGCCCTGCCCTGCTACT
TGCTCTACCTGCGGCACCATTGTCGTGGCTACATCATCCTCTCCCACCTGTCCAAGCTCAAGATGGTCCTGGGTGTCCTGCTGTGGTGCG
TCTCCTGGGCGGACCTTTTTTACTCCTTCCATGGCCTGGTCCATGGCCGGGCCCCTGCCCCTGTTTTCTTTGTCACCCCCTTGGTGGTGG
GGGTCACCATGCTGCTGGCCACCCTGCTGATACAGTATGAGCGGCTGCAGGGCGTACAGTCTTCGGGGGTCCTCATTATCTTCTGGTTCC
TGTGTGTGGTCTGCGCCATCGTCCCATTCCGCTCCAAGATCCTTTTAGCCAAGGCAGAGGGTGAGATCTCAGACCCCTTCCGCTTCACCA
CCTTCTACATCCACTTTGCCCTGGTACTCTCTGCCCTCATCTTGGCCTGCTTCAGGGAGAAACCTCCATTTTTCTCCGCAAAGAATGTCG
ACCCTAACCCCTACCCTGAGACCAGCGCTGGCTTTCTCTCCCGCCTGTTTTTCTGGTGGTTCACAAAGATGGCCATCTATGGCTACCGGC
ATCCCCTGGAGGAGAAGGACCTCTGGTCCCTAAAGGAAGAGGACAGATCCCAGATGGTGGTGCAGCAGCTGCTGGAGGCATGGAGGAAGC
AGGAAAAGCAGACGGCACGACACAAGGCTTCAGCAGCACCTGGGAAAAATGCCTCCGGCGAGGACGAGGTGCTGCTGGGTGCCCGGCCCA
GGCCCCGGAAGCCCTCCTTCCTGAAGGCCCTGCTGGCCACCTTCGGCTCCAGCTTCCTCATCAGTGCCTGCTTCAAGCTTATCCAGGACC
TGCTCTCCTTCATCAATCCACAGCTGCTCAGCATCCTGATCAGGTTTATCTCCAACCCCATGGCCCCCTCCTGGTGGGGCTTCCTGGTGG
CTGGGCTGATGTTCCTGTGCTCCATGATGCAGTCGCTGATCTTACAACACTATTACCACTACATCTTTGTGACTGGGGTGAAGTTTCGTA
CTGGGATCATGGGTGTCATCTACAGGAAGGCTCTGGTTATCACCAACTCAGTCAAACGTGCGTCCACTGTGGGGGAAATTGTCAACCTCA
TGTCAGTGGATGCCCAGCGCTTCATGGACCTTGCCCCCTTCCTCAATCTGCTGTGGTCAGCACCCCTGCAGATCATCCTGGCGATCTACT
TCCTCTGGCAGAACCTAGGTCCCTCTGTCCTGGCTGGAGTCGCTTTCATGGTCTTGCTGATTCCACTCAACGGAGCTGTGGCCGTGAAGA
TGCGCGCCTTCCAGGTAAAGCAAATGAAATTGAAGGACTCGCGCATCAAGCTGATGAGTGAGATCCTGAACGGCATCAAGGTGCTGAAGC
TGTACGCCTGGGAGCCCAGCTTCCTGAAGCAGGTGGAGGGCATCAGGCAGGGTGAGCTCCAGCTGCTGCGCACGGCGGCCTACCTCCACA
CCACAACCACCTTCACCTGGATGTGCAGCCCCTTCCTGGTGACCCTGATCACCCTCTGGGTGTACGTGTACGTGGACCCAAACAATGTGC
TGGACGCCGAGAAGGCCTTTGTGTCTGTGTCCTTGTTTAATATCTTAAGACTTCCCCTCAACATGCTGCCCCAGTTAATCAGCAACCTGA
CTCAGGCCAGTGTGTCTCTGAAACGGATCCAGCAATTCCTGAGCCAAGAGGAACTTGACCCCCAGAGTGTGGAAAGAAAGACCATCTCCC
CAGGCTATGCCATCACCATACACAGTGGCACCTTCACCTGGGCCCAGGACCTGCCCCCCACTCTGCACAGCCTAGACATCCAGGTCCCGA
AAGGGGCACTGGTGGCCGTGGTGGGGCCTGTGGGCTGTGGGAAGTCCTCCCTGGTGTCTGCCCTGCTGGGAGAGATGGAGAAGCTAGAAG
GCAAAGTGCACATGAAGGGCTCCGTGGCCTATGTGCCCCAGCAGGCATGGATCCAGAACTGCACTCTTCAGGAAAACGTGCTTTTCGGCA
AAGCCCTGAACCCCAAGCGCTACCAGCAGACTCTGGAGGCCTGTGCCTTGCTAGCTGACCTGGAGATGCTGCCTGGTGGGGATCAGACAG
AGATTGGAGAGAAGGGCATTAACCTGTCTGGGGGCCAGCGGCAGCGGGTCAGTCTGGCTCGAGCTGTTTACAGTGATGCCGATATTTTCT
TGCTGGATGACCCACTGTCCGCGGTGGACTCTCATGTGGCCAAGCACATCTTTGACCACGTCATCGGGCCAGAAGGCGTGCTGGCAGGCA
AGACGCGAGTGCTGGTGACGCACGGCATTAGCTTCCTGCCCCAGACAGACTTCATCATTGTGCTAGCTGATGGACAGGTGTCTGAGATGG
GCCCGTACCCAGCCCTGCTGCAGCGCAACGGCTCCTTTGCCAACTTTCTCTGCAACTATGCCCCCGATGAGGACCAAGGGCACCTGGAGG
ACAGCTGGACCGCGTTGGAAGGTGCAGAGGATAAGGAGGCACTGCTGATTGAAGACACACTCAGCAACCACACGGATCTGACAGACAATG
ATCCAGTCACCTATGTGGTCCAGAAGCAGTTTATGAGACAGCTGAGTGCCCTGTCCTCAGATGGGGAGGGACAGGGTCGGCCTGTACCCC
GGAGGCACCTGGGTCCATCAGAGAAGGTGCAGGTGACAGAGGCGAAGGCAGATGGGGCACTGACCCAGGAGGAGAAAGCAGCCATTGGCA
CTGTGGAGCTCAGTGTGTTCTGGGATTATGCCAAGGCCGTGGGGCTCTGTACCACGCTGGCCATCTGTCTCCTGTATGTGGGTCAAAGTG
CGGCTGCCATTGGAGCCAATGTGTGGCTCAGTGCCTGGACAAATGATGCCATGGCAGACAGTAGACAGAACAACACTTCCCTGAGGCTGG
GCGTCTATGCTGCTTTAGGAATTCTGCAAGGGTTCTTGGTGATGCTGGCAGCCATGGCCATGGCAGCGGGTGGCATCCAGGCTGCCCGTG
TGTTGCACCAGGCACTGCTGCACAACAAGATACGCTCGCCACAGTCCTTCTTTGACACCACACCATCAGGCCGCATCCTGAACTGCTTCT
CCAAGGACATCTATGTCGTTGATGAGGTTCTGGCCCCTGTCATCCTCATGCTGCTCAATTCCTTCTTCAACGCCATCTCCACTCTTGTGG
TCATCATGGCCAGCACGCCGCTCTTCACTGTGGTCATCCTGCCCCTGGCTGTGCTCTACACCTTAGTGCAGCGCTTCTATGCAGCCACAT
CACGGCAACTGAAGCGGCTGGAATCAGTCAGCCGCTCACCTATCTACTCCCACTTTTCGGAGACAGTGACTGGTGCCAGTGTCATCCGGG
CCTACAACCGCAGCCGGGATTTTGAGATCATCAGTGATACTAAGGTGGATGCCAACCAGAGAAGCTGCTACCCCTACATCATCTCCAACC
GGTGGCTGAGCATCGGAGTGGAGTTCGTGGGGAACTGCGTGGTGCTCTTTGCTGCACTATTTGCCGTCATCGGGAGGAGCAGCCTGAACC
CGGGGCTGGTGGGCCTTTCTGTGTCCTACTCCTTGCAGGTGACATTTGCTCTGAACTGGATGATACGAATGATGTCAGATTTGGAATCTA
ACATCGTGGCTGTGGAGAGGGTCAAGGAGTACTCCAAGACAGAGACAGAGGCGCCCTGGGTGGTGGAAGGCAGCCGCCCTCCCGAAGGTT
GGCCCCCACGTGGGGAGGTGGAGTTCCGGAATTATTCTGTGCGCTACCGGCCGGGCCTAGACCTGGTGCTGAGAGACCTGAGTCTGCATG
TGCACGGTGGCGAGAAGGTGGGGATCGTGGGCCGCACTGGGGCTGGCAAGTCTTCCATGACCCTTTGCCTGTTCCGCATCCTGGAGGCGG
CAAAGGGTGAAATCCGCATTGATGGCCTCAATGTGGCAGACATCGGCCTCCATGACCTGCGCTCTCAGCTGACCATCATCCCGCAGGACC
CCATCCTGTTCTCGGGGACCCTGCGCATGAACCTGGACCCCTTCGGCAGCTACTCAGAGGAGGACATTTGGTGGGCTTTGGAGCTGTCCC
ACCTGCACACGTTTGTGAGCTCCCAGCCGGCAGGCCTGGACTTCCAGTGCTCAGAGGGCGGGGAGAATCTCAGCGTGGGCCAGAGGCAGC
TCGTGTGCCTGGCCCGAGCCCTGCTCCGCAAGAGCCGCATCCTGGTTTTAGACGAGGCCACAGCTGCCATCGACCTGGAGACTGACAACC
TCATCCAGGCTACCATCCGCACCCAGTTTGATACCTGCACTGTCCTGACCATCGCACACCGGCTTAACACTATCATGGACTACACCAGGG
TCCTGGTCCTGGACAAAGGAGTAGTAGCTGAATTTGATTCTCCAGCCAACCTCATTGCAGCTAGAGGCATCTTCTACGGGATGGCCAGAG
ATGCTGGACTTGCCTAAAATATATTCCTGAGATTTCCTCCTGGCCTTTCCTGGTTTTCATCAGGAAGGAAATGACACCAAATATGTCCGC
AGAATGGACTTGATAGCAAACACTGGGGGCACCTTAAGATTTTGCACCTGTAAAGTGCCTTACAGGGTAACTGTGCTGAATGCTTTAGAT
GAGGAAATGATCCCCAAGTGGTGAATGACACGCCTAAGGTCACAGCTAGTTTGAGCCAGTTAGACTAGTCCCCGGTCTCCCGATTCCCAA
CTGAGTGTTATTTGCACACTGCACTGTTTTCAAATAACGATTTTATGAAATGACCTCTGTCCTCCCTCTGATTTTTCATATTTTCTAAAG
TTTCGTTTCTGTTTTTTAATAAAAAGCTTTTTCCTCCTGGAACAGAAGACAGCTGCTGGGTCAGGCCACCCCTAGGAACTCAGTCCTGTA
CTCTGGGGTGCTGCCTGAATCCATTAAAAATGGGAGTACTGATGAAATAAAACTACATGGTCAACAGTATATACACAGTAGTCTTTTTGC
ACTTGTTCACAAGGTTTGGGGATTAGGATCTTTGGAGGAGGCCAAGAGGAAGACTTTCTACACATGTACATGGTTGTAGTTACCTGAACT
TCAGACCCAAGAGCTCTTGGCTGCAAATATTGCCTTCACAGCCAAAATTCCCTGGGTAATTGCCAGTAGCTCCTGCTCTGCTGTGCAGAT
ATTGTAAAACGGTGAGAAAGGCCCTGAAATCTGACCTGGGGCCTCTTGGGAAAGCTGCTGTGAACACCTCCACGTTAATGTCATCCCTCA
GCCCTCTATGCCTGTTTCTCTAGGGACTGAGAAGTGCATGATGCTTTTACTTCCTTGCTCATTTCGAAGTCTGTTCCAGACAGTTCCTAT
AACCAGTGAGGCCTCCAAGTCATTCATTTTCCTCAGTCTAGCCAAAGCTGAATGTGTGAGCACAAAGAAGCCGAGAGGCCACCTCCTGCC

>In-frame_MED1_ENST00000300651_chr17_37604051_-_ABCC3_ENST00000285238_chr17_48733193_+_5947nt
ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG
ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG
GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA
TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGACT
CCAACCTGTCTGTGCACACAGAAAACCCGGACCTCACTCCCTGCTTCCAGAACTCCCTGCTGGCCTGGGTGCCCTGCATCTACCTGTGGG
TCGCCCTGCCCTGCTACTTGCTCTACCTGCGGCACCATTGTCGTGGCTACATCATCCTCTCCCACCTGTCCAAGCTCAAGATGGTCCTGG
GTGTCCTGCTGTGGTGCGTCTCCTGGGCGGACCTTTTTTACTCCTTCCATGGCCTGGTCCATGGCCGGGCCCCTGCCCCTGTTTTCTTTG
TCACCCCCTTGGTGGTGGGGGTCACCATGCTGCTGGCCACCCTGCTGATACAGTATGAGCGGCTGCAGGGCGTACAGTCTTCGGGGGTCC
TCATTATCTTCTGGTTCCTGTGTGTGGTCTGCGCCATCGTCCCATTCCGCTCCAAGATCCTTTTAGCCAAGGCAGAGGGTGAGATCTCAG
ACCCCTTCCGCTTCACCACCTTCTACATCCACTTTGCCCTGGTACTCTCTGCCCTCATCTTGGCCTGCTTCAGGGAGAAACCTCCATTTT
TCTCCGCAAAGAATGTCGACCCTAACCCCTACCCTGAGACCAGCGCTGGCTTTCTCTCCCGCCTGTTTTTCTGGTGGTTCACAAAGATGG
CCATCTATGGCTACCGGCATCCCCTGGAGGAGAAGGACCTCTGGTCCCTAAAGGAAGAGGACAGATCCCAGATGGTGGTGCAGCAGCTGC
TGGAGGCATGGAGGAAGCAGGAAAAGCAGACGGCACGACACAAGGCTTCAGCAGCACCTGGGAAAAATGCCTCCGGCGAGGACGAGGTGC
TGCTGGGTGCCCGGCCCAGGCCCCGGAAGCCCTCCTTCCTGAAGGCCCTGCTGGCCACCTTCGGCTCCAGCTTCCTCATCAGTGCCTGCT
TCAAGCTTATCCAGGACCTGCTCTCCTTCATCAATCCACAGCTGCTCAGCATCCTGATCAGGTTTATCTCCAACCCCATGGCCCCCTCCT
GGTGGGGCTTCCTGGTGGCTGGGCTGATGTTCCTGTGCTCCATGATGCAGTCGCTGATCTTACAACACTATTACCACTACATCTTTGTGA
CTGGGGTGAAGTTTCGTACTGGGATCATGGGTGTCATCTACAGGAAGGCTCTGGTTATCACCAACTCAGTCAAACGTGCGTCCACTGTGG
GGGAAATTGTCAACCTCATGTCAGTGGATGCCCAGCGCTTCATGGACCTTGCCCCCTTCCTCAATCTGCTGTGGTCAGCACCCCTGCAGA
TCATCCTGGCGATCTACTTCCTCTGGCAGAACCTAGGTCCCTCTGTCCTGGCTGGAGTCGCTTTCATGGTCTTGCTGATTCCACTCAACG
GAGCTGTGGCCGTGAAGATGCGCGCCTTCCAGGTAAAGCAAATGAAATTGAAGGACTCGCGCATCAAGCTGATGAGTGAGATCCTGAACG
GCATCAAGGTGCTGAAGCTGTACGCCTGGGAGCCCAGCTTCCTGAAGCAGGTGGAGGGCATCAGGCAGGGTGAGCTCCAGCTGCTGCGCA
CGGCGGCCTACCTCCACACCACAACCACCTTCACCTGGATGTGCAGCCCCTTCCTGGTGACCCTGATCACCCTCTGGGTGTACGTGTACG
TGGACCCAAACAATGTGCTGGACGCCGAGAAGGCCTTTGTGTCTGTGTCCTTGTTTAATATCTTAAGACTTCCCCTCAACATGCTGCCCC
AGTTAATCAGCAACCTGACTCAGGCCAGTGTGTCTCTGAAACGGATCCAGCAATTCCTGAGCCAAGAGGAACTTGACCCCCAGAGTGTGG
AAAGAAAGACCATCTCCCCAGGCTATGCCATCACCATACACAGTGGCACCTTCACCTGGGCCCAGGACCTGCCCCCCACTCTGCACAGCC
TAGACATCCAGGTCCCGAAAGGGGCACTGGTGGCCGTGGTGGGGCCTGTGGGCTGTGGGAAGTCCTCCCTGGTGTCTGCCCTGCTGGGAG
AGATGGAGAAGCTAGAAGGCAAAGTGCACATGAAGGGCTCCGTGGCCTATGTGCCCCAGCAGGCATGGATCCAGAACTGCACTCTTCAGG
AAAACGTGCTTTTCGGCAAAGCCCTGAACCCCAAGCGCTACCAGCAGACTCTGGAGGCCTGTGCCTTGCTAGCTGACCTGGAGATGCTGC
CTGGTGGGGATCAGACAGAGATTGGAGAGAAGGGCATTAACCTGTCTGGGGGCCAGCGGCAGCGGGTCAGTCTGGCTCGAGCTGTTTACA
GTGATGCCGATATTTTCTTGCTGGATGACCCACTGTCCGCGGTGGACTCTCATGTGGCCAAGCACATCTTTGACCACGTCATCGGGCCAG
AAGGCGTGCTGGCAGGCAAGACGCGAGTGCTGGTGACGCACGGCATTAGCTTCCTGCCCCAGACAGACTTCATCATTGTGCTAGCTGATG
GACAGGTGTCTGAGATGGGCCCGTACCCAGCCCTGCTGCAGCGCAACGGCTCCTTTGCCAACTTTCTCTGCAACTATGCCCCCGATGAGG
ACCAAGGGCACCTGGAGGACAGCTGGACCGCGTTGGAAGGTGCAGAGGATAAGGAGGCACTGCTGATTGAAGACACACTCAGCAACCACA
CGGATCTGACAGACAATGATCCAGTCACCTATGTGGTCCAGAAGCAGTTTATGAGACAGCTGAGTGCCCTGTCCTCAGATGGGGAGGGAC
AGGGTCGGCCTGTACCCCGGAGGCACCTGGGTCCATCAGAGAAGGTGCAGGTGACAGAGGCGAAGGCAGATGGGGCACTGACCCAGGAGG
AGAAAGCAGCCATTGGCACTGTGGAGCTCAGTGTGTTCTGGGATTATGCCAAGGCCGTGGGGCTCTGTACCACGCTGGCCATCTGTCTCC
TGTATGTGGGTCAAAGTGCGGCTGCCATTGGAGCCAATGTGTGGCTCAGTGCCTGGACAAATGATGCCATGGCAGACAGTAGACAGAACA
ACACTTCCCTGAGGCTGGGCGTCTATGCTGCTTTAGGAATTCTGCAAGGGTTCTTGGTGATGCTGGCAGCCATGGCCATGGCAGCGGGTG
GCATCCAGGCTGCCCGTGTGTTGCACCAGGCACTGCTGCACAACAAGATACGCTCGCCACAGTCCTTCTTTGACACCACACCATCAGGCC
GCATCCTGAACTGCTTCTCCAAGGACATCTATGTCGTTGATGAGGTTCTGGCCCCTGTCATCCTCATGCTGCTCAATTCCTTCTTCAACG
CCATCTCCACTCTTGTGGTCATCATGGCCAGCACGCCGCTCTTCACTGTGGTCATCCTGCCCCTGGCTGTGCTCTACACCTTAGTGCAGC
GCTTCTATGCAGCCACATCACGGCAACTGAAGCGGCTGGAATCAGTCAGCCGCTCACCTATCTACTCCCACTTTTCGGAGACAGTGACTG
GTGCCAGTGTCATCCGGGCCTACAACCGCAGCCGGGATTTTGAGATCATCAGTGATACTAAGGTGGATGCCAACCAGAGAAGCTGCTACC
CCTACATCATCTCCAACCGGTGGCTGAGCATCGGAGTGGAGTTCGTGGGGAACTGCGTGGTGCTCTTTGCTGCACTATTTGCCGTCATCG
GGAGGAGCAGCCTGAACCCGGGGCTGGTGGGCCTTTCTGTGTCCTACTCCTTGCAGGTGACATTTGCTCTGAACTGGATGATACGAATGA
TGTCAGATTTGGAATCTAACATCGTGGCTGTGGAGAGGGTCAAGGAGTACTCCAAGACAGAGACAGAGGCGCCCTGGGTGGTGGAAGGCA
GCCGCCCTCCCGAAGGTTGGCCCCCACGTGGGGAGGTGGAGTTCCGGAATTATTCTGTGCGCTACCGGCCGGGCCTAGACCTGGTGCTGA
GAGACCTGAGTCTGCATGTGCACGGTGGCGAGAAGGTGGGGATCGTGGGCCGCACTGGGGCTGGCAAGTCTTCCATGACCCTTTGCCTGT
TCCGCATCCTGGAGGCGGCAAAGGGTGAAATCCGCATTGATGGCCTCAATGTGGCAGACATCGGCCTCCATGACCTGCGCTCTCAGCTGA
CCATCATCCCGCAGGACCCCATCCTGTTCTCGGGGACCCTGCGCATGAACCTGGACCCCTTCGGCAGCTACTCAGAGGAGGACATTTGGT
GGGCTTTGGAGCTGTCCCACCTGCACACGTTTGTGAGCTCCCAGCCGGCAGGCCTGGACTTCCAGTGCTCAGAGGGCGGGGAGAATCTCA
GCGTGGGCCAGAGGCAGCTCGTGTGCCTGGCCCGAGCCCTGCTCCGCAAGAGCCGCATCCTGGTTTTAGACGAGGCCACAGCTGCCATCG
ACCTGGAGACTGACAACCTCATCCAGGCTACCATCCGCACCCAGTTTGATACCTGCACTGTCCTGACCATCGCACACCGGCTTAACACTA
TCATGGACTACACCAGGGTCCTGGTCCTGGACAAAGGAGTAGTAGCTGAATTTGATTCTCCAGCCAACCTCATTGCAGCTAGAGGCATCT
TCTACGGGATGGCCAGAGATGCTGGACTTGCCTAAAATATATTCCTGAGATTTCCTCCTGGCCTTTCCTGGTTTTCATCAGGAAGGAAAT
GACACCAAATATGTCCGCAGAATGGACTTGATAGCAAACACTGGGGGCACCTTAAGATTTTGCACCTGTAAAGTGCCTTACAGGGTAACT
GTGCTGAATGCTTTAGATGAGGAAATGATCCCCAAGTGGTGAATGACACGCCTAAGGTCACAGCTAGTTTGAGCCAGTTAGACTAGTCCC
CGGTCTCCCGATTCCCAACTGAGTGTTATTTGCACACTGCACTGTTTTCAAATAACGATTTTATGAAATGACCTCTGTCCTCCCTCTGAT
TTTTCATATTTTCTAAAGTTTCGTTTCTGTTTTTTAATAAAAAGCTTTTTCCTCCTGGAACAGAAGACAGCTGCTGGGTCAGGCCACCCC
TAGGAACTCAGTCCTGTACTCTGGGGTGCTGCCTGAATCCATTAAAAATGGGAGTACTGATGAAATAAAACTACATGGTCAACAGTATAT
ACACAGTAGTCTTTTTGCACTTGTTCACAAGGTTTGGGGATTAGGATCTTTGGAGGAGGCCAAGAGGAAGACTTTCTACACATGTACATG
GTTGTAGTTACCTGAACTTCAGACCCAAGAGCTCTTGGCTGCAAATATTGCCTTCACAGCCAAAATTCCCTGGGTAATTGCCAGTAGCTC
CTGCTCTGCTGTGCAGATATTGTAAAACGGTGAGAAAGGCCCTGAAATCTGACCTGGGGCCTCTTGGGAAAGCTGCTGTGAACACCTCCA
CGTTAATGTCATCCCTCAGCCCTCTATGCCTGTTTCTCTAGGGACTGAGAAGTGCATGATGCTTTTACTTCCTTGCTCATTTCGAAGTCT
GTTCCAGACAGTTCCTATAACCAGTGAGGCCTCCAAGTCATTCATTTTCCTCAGTCTAGCCAAAGCTGAATGTGTGAGCACAAAGAAGCC
GAGAGGCCACCTCCTGCCCAGAGAGAAGCCACCCACACTCCCAGGTTGGCAGACAAGATGTGAGGGGTGAATTAAATTTGTTTTCTTGAG


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FusionGenePPI for MED1_ABCC3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MED1MED10, MED9, MED29, MED19, MED28, MED26, PPARGC1A, NR3C1, YWHAQ, TGS1, TP53, CDK8, VDR, MED1, HNF4A, THRA, THRAP3, MED24, AR, ESR1, ESR2, MED13, MED6, MED16, MED17, MED20, MED14, MED12, MED23, MED27, MED4, MED7, MED8, MED30, MED22, MED31, MED15, MED18, MED11, MED25, POLR2A, MED21, POLR2F, GABPA, GATA1, ATM, POU1F1, GATA2, PARP1, RXRA, TRRAP, PPARG, RARA, SREBF1, KAT2A, SUPT3H, SUPT7L, MYC, CCNC, CDK19, POLR2E, CDK9, ZC3H13, TRIP4, OBFC1, QKI, TADA2A, TRA, NR1H2, KIF1A, BRD4, CTDP1, NCOA6, ELAVL1, MDM2, ZNF281, ZNF326, RALY, SETD7, FBXW7, MED13L, EPAS1, EZH2, BAG3, GJB5, PIN1, POLL, NR1I3, TCL1B, HNRNPC, NTRK1, POLR2G, EMC2, SMEK1, MED12L, RPAP2, POLR2D, BIRC5, PLK1, SPAG5ABCC3MLH1, ATP9A, CANX, IDH3A, VCP, EEF2, VDAC1, VDAC2, VDAC3


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-21716_590441582ESR1
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217656_1066441582ESR1
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-21816_59044557ESR1
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218656_106644557ESR1
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217681_715441582GATA1
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218681_71544557GATA1
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217622_701441582PPARGC1A and THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218622_70144557PPARGC1A and THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217108_212441582the Mediator complex
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217215_390441582the Mediator complex
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218108_21244557the Mediator complex
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218215_39044557the Mediator complex
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-2171_670441582the Mediator complex and THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-2181_67044557the Mediator complex and THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217405_644441582THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218405_64444557THRA
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-2171249_1421441582TP53
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-2181249_142144557TP53
HgeneMED1chr17:37604051chr17:48733193ENST00000300651-217542_789441582VDR
HgeneMED1chr17:37604051chr17:48733193ENST00000394287-218542_78944557VDR


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MED1_ABCC3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MED1_ABCC3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMED1C0014175Endometriosis1CTD_human
HgeneMED1C2239176Liver carcinoma1CTD_human
HgeneMED1C4277682Chemical and Drug Induced Liver Injury1CTD_human
TgeneABCC3C0003873Rheumatoid Arthritis1CTD_human
TgeneABCC3C0008370Cholestasis1CTD_human
TgeneABCC3C0009404Colorectal Neoplasms1CTD_human