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Fusion gene ID: 21391 |
FusionGeneSummary for MDM2_POLR3B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MDM2_POLR3B | Fusion gene ID: 21391 | Hgene | Tgene | Gene symbol | MDM2 | POLR3B | Gene ID | 4193 | 55703 |
| Gene name | MDM2 proto-oncogene | RNA polymerase III subunit B | |
| Synonyms | ACTFS|HDMX|hdm2 | C128|HLD8|INMAP|RPC2 | |
| Cytomap | 12q15 | 12q23.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, hum | DNA-directed RNA polymerase III subunit RPC2DNA-directed RNA polymerase III 127.6 kDa polypeptideDNA-directed RNA polymerase III subunit BRNA polymerase III subunit C2interphase nucleus and mitotic apparatus associated proteinpolymerase (RNA) III (DN | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | Q00987 | Q9NW08 | |
| Ensembl transtripts involved in fusion gene | ENST00000462284, ENST00000356290, ENST00000540827, ENST00000258149, ENST00000428863, ENST00000393412, ENST00000258148, ENST00000544561, ENST00000393410, ENST00000393413, ENST00000517852, ENST00000545204, ENST00000350057, ENST00000360430, ENST00000299252, ENST00000348801, ENST00000478070, ENST00000544125, | ENST00000228347, ENST00000539066, ENST00000549195, | |
| Fusion gene scores | * DoF score | 24 X 14 X 8=2688 | 2 X 2 X 2=8 |
| # samples | 25 | 2 | |
| ** MAII score | log2(25/2688*10)=-3.42653313811667 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: MDM2 [Title/Abstract] AND POLR3B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MDM2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 9271120|17310983 |
| Hgene | MDM2 | GO:0006511 | ubiquitin-dependent protein catabolic process | 11278372|15314173|16173922|17310983 |
| Hgene | MDM2 | GO:0016567 | protein ubiquitination | 9450543|15878855|19656744|20153724 |
| Hgene | MDM2 | GO:0031648 | protein destabilization | 9529249|10360174|15314173 |
| Hgene | MDM2 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 11278372 |
| Hgene | MDM2 | GO:0034504 | protein localization to nucleus | 10360174 |
| Hgene | MDM2 | GO:0042176 | regulation of protein catabolic process | 9153395 |
| Hgene | MDM2 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator | 9529249|10360174 |
| Hgene | MDM2 | GO:0045184 | establishment of protein localization | 10360174 |
| Hgene | MDM2 | GO:0045892 | negative regulation of transcription, DNA-templated | 9271120 |
| Hgene | MDM2 | GO:0065003 | protein-containing complex assembly | 10608892|12915590 |
| Hgene | MDM2 | GO:0071157 | negative regulation of cell cycle arrest | 9529249 |
| Hgene | MDM2 | GO:0071480 | cellular response to gamma radiation | 16213212 |
| Hgene | MDM2 | GO:0072717 | cellular response to actinomycin D | 15314173 |
| Hgene | MDM2 | GO:1901797 | negative regulation of signal transduction by p53 class mediator | 16173922 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A48N-01A | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000462284 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000462284 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000462284 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000356290 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000356290 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000356290 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000540827 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000540827 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000540827 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000258149 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000258149 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000258149 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000428863 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000428863 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000428863 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393412 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393412 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000393412 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000258148 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000258148 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000258148 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000544561 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000544561 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000544561 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393410 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393410 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000393410 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393413 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000393413 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000393413 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000517852 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000517852 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000517852 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000545204 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000545204 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000545204 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000350057 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000350057 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000350057 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000360430 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000360430 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000360430 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000299252 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| In-frame | ENST00000299252 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| 5CDS-3UTR | ENST00000299252 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000348801 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000348801 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000348801 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000478070 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000478070 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000478070 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000544125 | ENST00000228347 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3CDS | ENST00000544125 | ENST00000539066 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
| intron-3UTR | ENST00000544125 | ENST00000549195 | MDM2 | chr12 | 69230529 | + | POLR3B | chr12 | 106820975 | + |
Top |
FusionProtFeatures for MDM2_POLR3B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MDM2 | POLR3B |
| DNA-dependent RNA polymerase catalyzes the transcriptionof DNA into RNA using the four ribonucleoside triphosphates assubstrates. Second largest core component of RNA polymerase IIIwhich synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposedto contribute to the polymerase catalytic activity and forms thepolymerase active center together with the largest subunit. PolIII is composed of mobile elements and RPC2 is part of the coreelement with the central large cleft and probably a clamp elementthat moves to open and close the cleft (By similarity). Plays akey role in sensing and limiting infection by intracellularbacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensorinvolved in innate immune response. Can sense non-self dsDNA thatserves as template for transcription into dsRNA. The non-self RNApolymerase III transcripts, such as Epstein-Barr virus-encodedRNAs (EBERs) induce type I interferon and NF- Kappa-B through theRIG-I pathway. {ECO:0000250, ECO:0000269|PubMed:19609254,ECO:0000269|PubMed:19631370}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 210_215 | 245 | 437 | Compositional bias | Note=Poly-Ser |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 210_215 | 306 | 498 | Compositional bias | Note=Poly-Ser |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 243_301 | 306 | 498 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 27_107 | 245 | 437 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 27_107 | 130 | 322 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 27_107 | 130 | 322 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 27_107 | 105 | 297 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 27_107 | 306 | 498 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 27_107 | 105 | 297 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 179_185 | 245 | 437 | Motif | Nuclear localization signal |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 190_202 | 245 | 437 | Motif | Note=Nuclear export signal |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 179_185 | 306 | 498 | Motif | Nuclear localization signal |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 190_202 | 306 | 498 | Motif | Note=Nuclear export signal |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 210_304 | 306 | 498 | Region | Note=ARF-binding |
| Tgene | >POLR3B | chr12:69230529 | chr12:106820975 | ENST00000228347 | + | 11 | 28 | 1080_1095 | 367 | 1134 | Zinc finger | Note=C4-type |
| Tgene | >POLR3B | chr12:69230529 | chr12:106820975 | ENST00000539066 | + | 11 | 28 | 1080_1095 | 309 | 1076 | Zinc finger | Note=C4-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 243_301 | 245 | 437 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 210_215 | 130 | 322 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 243_301 | 130 | 322 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 210_215 | 0 | 266 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 243_301 | 0 | 266 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 210_215 | 130 | 322 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 243_301 | 130 | 322 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 210_215 | 105 | 297 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 243_301 | 105 | 297 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 210_215 | -92 | 219 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 243_301 | -92 | 219 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 210_215 | 0 | 219 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 243_301 | 0 | 219 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 210_215 | -102 | 271 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 243_301 | -102 | 271 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 210_215 | 105 | 297 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 243_301 | 105 | 297 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 27_107 | 0 | 266 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 27_107 | -92 | 219 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 27_107 | 0 | 219 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 27_107 | -102 | 271 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 466_473 | 245 | 437 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 179_185 | 130 | 322 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 190_202 | 130 | 322 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 466_473 | 130 | 322 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 179_185 | 0 | 266 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 190_202 | 0 | 266 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 466_473 | 0 | 266 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 179_185 | 130 | 322 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 190_202 | 130 | 322 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 466_473 | 130 | 322 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 179_185 | 105 | 297 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 190_202 | 105 | 297 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 466_473 | 105 | 297 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 179_185 | -92 | 219 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 190_202 | -92 | 219 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 466_473 | -92 | 219 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 179_185 | 0 | 219 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 190_202 | 0 | 219 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 466_473 | 0 | 219 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 179_185 | -102 | 271 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 190_202 | -102 | 271 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 466_473 | -102 | 271 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 466_473 | 306 | 498 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 179_185 | 105 | 297 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 190_202 | 105 | 297 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 466_473 | 105 | 297 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 210_304 | 245 | 437 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 242_331 | 245 | 437 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 210_304 | 130 | 322 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 242_331 | 130 | 322 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 210_304 | 0 | 266 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 242_331 | 0 | 266 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 210_304 | 130 | 322 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 242_331 | 130 | 322 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 210_304 | 105 | 297 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 242_331 | 105 | 297 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 210_304 | -92 | 219 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 242_331 | -92 | 219 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 210_304 | 0 | 219 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 242_331 | 0 | 219 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 210_304 | -102 | 271 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 242_331 | -102 | 271 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 242_331 | 306 | 498 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 210_304 | 105 | 297 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 242_331 | 105 | 297 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 299_328 | 245 | 437 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 438_479 | 245 | 437 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 299_328 | 130 | 322 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 438_479 | 130 | 322 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 299_328 | 0 | 266 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 438_479 | 0 | 266 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 299_328 | 130 | 322 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 438_479 | 130 | 322 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 299_328 | 105 | 297 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 438_479 | 105 | 297 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 299_328 | -92 | 219 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 438_479 | -92 | 219 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 299_328 | 0 | 219 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 438_479 | 0 | 219 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 299_328 | -102 | 271 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 438_479 | -102 | 271 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 299_328 | 306 | 498 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 438_479 | 306 | 498 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 299_328 | 105 | 297 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 438_479 | 105 | 297 | Zinc finger | RING-type |
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FusionGeneSequence for MDM2_POLR3B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_1073aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEE GQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIST GNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPI VKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKK QKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGK QAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKR YTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMI SSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYG TAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEME >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_1073aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEE GQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIST GNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPI VKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKK QKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGK QAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKR YTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMI SSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYG TAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEME >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_897aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYS LSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVN AISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDME DGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYI IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQC AMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKC TLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGR FHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_897aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYS LSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVN AISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDME DGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYI IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQC AMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKC TLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGR FHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_872aa MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE SDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSR LSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELS YPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFE DFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLL AYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKP IWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPE IGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYN YLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISS >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_872aa MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE SDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSR LSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELS YPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFE DFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLL AYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKP IWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPE IGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYN YLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISS >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_1012aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPS FSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW LDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVI PKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPS DTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFV SISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPF TLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIE DALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEG SNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPH GFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHA RARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKL >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_1012aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPS FSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW LDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVI PKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPS DTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFV SISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPF TLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIE DALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEG SNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPH GFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHA RARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKL >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_1018aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS EHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKK IADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQW GMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAG YINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTH LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSY SGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPD IIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMV LDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRI >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_1018aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS EHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKK IADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQW GMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAG YINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTH LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSY SGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPD IIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMV LDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRI >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_1042aa MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDP EISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMM TRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLN GNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEY LDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKT KTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDAD GICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHG QKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSG ITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQ >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_1042aa MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDP EISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMM TRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLN GNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEY LDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKT KTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDAD GICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHG QKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSG ITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQ >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_872aa MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE SDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSR LSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELS YPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFE DFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLL AYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKP IWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPE IGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYN YLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISS >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_872aa MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE SDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSR LSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELS YPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFE DFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLL AYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKP IWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPE IGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYN YLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISS >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_897aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYS LSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVN AISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDME DGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYI IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQC AMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKC TLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGR FHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_897aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYS LSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLALLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVN AISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDME DGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYI IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQC AMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKC TLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGR FHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3219nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA GGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGAT CCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTG ATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACC GGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATG ATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCT TCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATT GTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTT AATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTT GTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAA CAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAA TATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCC TTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAA CAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAG ACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATT GAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGA TACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCA GATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAA GGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATA TCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCAT GGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCA CACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGC ACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCC GGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCAT GCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAA CGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGG CAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAG >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3219nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA GGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGAT CCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTG ATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACC GGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATG ATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCT TCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATT GTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTT AATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTT GTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAA CAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAA TATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCC TTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAA CAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAG ACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATT GAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGA TACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCA GATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAA GGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATA TCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCAT GGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCA CACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGC ACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCC GGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCAT GCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAA CGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGG CAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAG >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_2691nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_2691nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_2616nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_2616nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3036nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3036nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3054nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGAT TCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAG ATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTG AATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATA TCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGG GGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATG GAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTG TTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGA TATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTAC ATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACAT GAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCAC TTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAG TGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAA AAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTAT AGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAA TGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACAT GAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACT CAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATT GAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAA TTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGAC ATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGC AGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAA GACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTG CTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGT CTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAG GTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATT >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3054nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGAT TCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAG ATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTG AATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATA TCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGG GGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATG GAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTG TTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGA TATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTAC ATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACAT GAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCAC TTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAG TGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAA AAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTAT AGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAA TGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACAT GAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACT CAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATT GAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAA TTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGAC ATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGC AGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAA GACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTG CTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGT CTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAG GTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATT >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3126nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3126nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_2616nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_2616nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_2691nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_2691nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_4170nt GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAG GGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTA ATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGA TCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGT CTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCC TCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACAC ACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGC TCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGAC TCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAA GGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATT TTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTA ATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCAC CGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATC TACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAG TTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTG TATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGA AACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGT CCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAG CAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTC CAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATT CTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGG CCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTT ATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGA AGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTC GTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTT CAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACG TGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGT ACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTC TCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAA ACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAA AGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAAT TTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTG TCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATA ATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATG >In-frame_MDM2_ENST00000462284_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_4168nt GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAG GGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTA ATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGA TCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGT CTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCC TCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACAC ACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGC TCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGAC TCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAA GGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATT TTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTA ATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCAC CGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATC TACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAG TTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTG TATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGA AACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGT CCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAG CAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTC CAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATT CTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGG CCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTT ATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGA AGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTC GTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTT CAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACG TGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGT ACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTC TCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAA ACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAA AGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAAT TTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTG TCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATA ATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATG >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3645nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTA CTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACT TGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACA TGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTG TAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGA GTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACT TGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTAT TATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAG TGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTT CTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCC AAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGT ACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTC ACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTG ATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTG GACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCT TTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGG ATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAG TGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCA TAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGA GACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACA TGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGC TGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACC TCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCC CCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCA CTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAG AGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCA AGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGT TAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGG ATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATAC TCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAG ATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAA TGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGG TCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAG TCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTG >In-frame_MDM2_ENST00000356290_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3643nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTA CTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACT TGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACA TGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTG TAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGA GTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACT TGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTAT TATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAG TGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTT CTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCC AAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGT ACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTC ACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTG ATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTG GACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCT TTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGG ATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAG TGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCA TAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGA GACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACA TGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGC TGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACC TCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCC CCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCA CTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAG AGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCA AGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGT TAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGG ATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATAC TCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAG ATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAA TGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGG TCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAG TCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTG >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3570nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG AGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTC TTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTG ATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAA TGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAA AAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTG GTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAG AAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAG ACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATC GATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATA TGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATT GTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGAC TTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACC AGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTG AGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCT CTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGA TGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAG TAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGT ACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGA TCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCG TCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGG GGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGG ATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCAT ACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCC TTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCA GTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCT GGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGA ACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAA CGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAG AGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGG CTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTT ACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGA ATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAA ACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCT >In-frame_MDM2_ENST00000540827_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3568nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG AGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTC TTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTG ATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAA TGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAA AAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTG GTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAG AAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAG ACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATC GATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATA TGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATT GTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGAC TTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACC AGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTG AGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCT CTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGA TGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAG TAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGT ACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGA TCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCG TCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGG GGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGG ATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCAT ACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCC TTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCA GTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCT GGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGA ACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAA CGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAG AGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGG CTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTT ACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGA ATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAA ACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCT >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3990nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAG GGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTA ATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGA TCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGT CTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCC TCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACAC ACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGC TCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGAC TCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAA GGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATT TTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTA ATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCAC CGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATC TACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAG TTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTG TATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGA AACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGT CCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAG CAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTC CAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATT CTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGG CCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTT ATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGA AGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTC GTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTT CAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACG TGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGT ACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTC TCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAA ACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAA AGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAAT TTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTG TCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATA ATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATG >In-frame_MDM2_ENST00000258149_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3988nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAG GGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTA ATTCTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGA TCACCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGT CTCGCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCC TCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACAC ACATCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGC TCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGAC TCATGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAA GGCTATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATT TTGAAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTA ATAAAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCAC CGAGAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATC TACTAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAG TTGCTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTG TATATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGA AACCTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGT CCATGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAG CAACAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTC CAGAAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATT CTGGCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGG CCGGTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTT ATAACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGA AGCTGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTC GTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTT CAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACG TGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGT ACAATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTC TCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAA ACAACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAA AGGATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAAT TTACCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTG TCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATA ATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATG >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3717nt CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGG AGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATT CTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCA CCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTC GCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCC AGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACA TCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCT CTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCA TGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGC TATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTG AAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATA AAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGA GAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTAC TAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTG CTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTAT ATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAAC CTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCA TGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAA CAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAG AAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTG GCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCG GTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATA ACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGC TGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTG ATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAA GTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGT CTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACA ATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCC TCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACA ACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGG ATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTA CCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCG TGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATG AATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAA >In-frame_MDM2_ENST00000258148_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3715nt CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGG AGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATT CTGAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCA CCAATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTC GCTTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCC AGCCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACA TCACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCT CTTACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCA TGAGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGC TATGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTG AAGATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATA AAGACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGA GAAACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTAC TAGCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTG CTGTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTAT ATAAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAAC CTATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCA TGCCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAA CAGACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAG AAATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTG GCATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCG GTGTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATA ACTACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGC TGAAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTG ATGGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAA GTGATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGT CTTCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACA ATGAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCC TCCTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACA ACCTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGG ATAAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTA CCATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCG TGGTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATG AATTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAA >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3775nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG CTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAG AGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCT CTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGA GATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCT TGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTC TTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAA TTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTC >In-frame_MDM2_ENST00000350057_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3773nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA CAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCT GAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATTGCCGACCAGGTGATT CCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAATGCTATTTCTACCGGA AATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCCGCACTGGGCATGATG ACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGAATGCTGTGTCCTTCG GACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAAGATGGACCCATTGTT AAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTTCTTGTCTTTCTTAAT GGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATATATCAATGAATTTGTT TCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATAATTGTCAAGAAACAG AAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAGAGTCTGGTTGAATAT TTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTGGAGATTGAACCCTTC ACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGTGCCATGGGGAAACAA GCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAACCCATGGTTAAGACA AAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGTGGCTATGATATTGAA GATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGTACGTTGAAACGATAC ACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAAATCTTAGATGCAGAT GGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAGATTCCTTTGGAAGGA AGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAAAAAGTGATGATATCT TCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTCAGCAGTCGTCATGGG CAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATCATCATGAACCCACAC GGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGATTCCACTACGGCACT GCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGACTATGTTACATCCGGC ATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTAGATAAAATGCATGCC CGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTCGGGGAAATGGAACGT GACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTTGATGTCTGTGGGCAG TGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCGTATGCCTGCAAGCTG CTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAAAAATGATTATTAAAG AGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCCTTGCGTATTCTCTCT CTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCCTCGAGCCATGGGAGA GATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACTTATGTGCTGATCTCT TGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAACCATATTCAAGATTC TTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGATAAATTTTCCCAACAA TTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTGTCAAGCAAGAATGTC >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3265nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT GAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTC CTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAAC CTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGAT AAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACC ATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTG GTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAA TTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAATA >In-frame_MDM2_ENST00000360430_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3263nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAG AGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCT GAAATGAAAAAGATTGCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACC AATGGCATGGTGAATGCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGC TTGTCATATATATCCGCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAG CCATCTCAGTGGGGAATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATC ACAACTGATATGGAAGATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCT TACCCAAATGTGTTTCTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATG AGAAGAGCAGGATATATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTA TGCAGACCCTACATAATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAA GATTTCTTACATGAGAGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAA GACACCACCCACTTGGAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGA AACACTTATCAGTGTGCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTA GCATATCCACAAAAACCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCT GTGATGAGCTATAGTGGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATAT AAAAATGCTAAATGTACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCT ATCTGGCGACATGAAATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATG CCCACAGTGACTCAGATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACA GACTCATATATTGAAAAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAA ATTGGAGACAAATTCAGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGC ATCTGTCCGGACATCATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGT GTGCTGGACGGCAGATTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAAC TACTTGGGGAAAGACTATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTG AAACACATGGTGCTAGATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGAT GGTGGCTTGCGTCTCGGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGT GATGCCTTTGAGGTTGATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCT TCCCTCCGTATTCCGTATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAAT GAATGAGGATGGAAAAAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTC CTGTGAAGAATTCCCTTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAAC CTTGATCATTGAGCCTCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGAT AAATAAGCTATTACTTATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACC ATATCTTCTGGCTAACCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTG GTGGCTGGCTCGGATAAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAA TTTGTTCCTACCTTGTCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAATA >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000228347_chr12_106820975_+_3340nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG TATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAA AAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCC TTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCC TCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACT TATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAA CCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGAT AAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTG TCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAATACTATTCGTTAAATAT >In-frame_MDM2_ENST00000299252_chr12_69230529_+_POLR3B_ENST00000539066_chr12_106820975_+_3338nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTATATCAAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCA TTTGAAGAAGATCCTGAAATTTCCTTAGCTCTTTTATCTCTTCTTTTTGAAGACTTGTTCAAAAAATTTAATTCTGAAATGAAAAAGATT GCCGACCAGGTGATTCCTAAGCAAAGAGCAGCCCAGTTTGATGTTGTCAAACACATGCGCCAAGACCAGATCACCAATGGCATGGTGAAT GCTATTTCTACCGGAAATTGGTCTTTAAAGAGATTTAAAATGGACCGCCAGGGTGTAACCCAAGTGCTGTCTCGCTTGTCATATATATCC GCACTGGGCATGATGACAAGAATCTCTTCCCAGTTTGAAAAAACGAGAAAAGTGAGTGGTCCTCGCTCCCTCCAGCCATCTCAGTGGGGA ATGCTGTGTCCTTCGGACACTCCTGAAGGAGAGGCATGTGGTTTGGTTAAAAACTTGGCCCTTATGACACACATCACAACTGATATGGAA GATGGACCCATTGTTAAATTAGCCAGTAACTTGGGAGTAGAAGATGTGAATTTATTATGTGGGGAAGAGCTCTCTTACCCAAATGTGTTT CTTGTCTTTCTTAATGGTAACATCTTAGGTGTCATTCGAGACCACAAAAAGCTAGTGAATACATTTCGACTCATGAGAAGAGCAGGATAT ATCAATGAATTTGTTTCCATCTCAACAAATCTTACAGATCGATGTGTCTATATTTCTTCTGATGGGGGAAGGCTATGCAGACCCTACATA ATTGTCAAGAAACAGAAGCCAGCAGTCACAAATAAACATATGGAAGAGCTGGCCCAAGGGTACAGGAATTTTGAAGATTTCTTACATGAG AGTCTGGTTGAATATTTAGATGTGAATGAAGAAAATGATTGTAACATTGCACTGTACGAACACACAATTAATAAAGACACCACCCACTTG GAGATTGAACCCTTCACTCTTCTCGGCGTGTGTGCTGGACTTATCCCATACCCTCACCATAACCAGTCACCGAGAAACACTTATCAGTGT GCCATGGGGAAACAAGCCATGGGTACTATAGGATACAACCAGCGAAACAGAATTGATACTCTCATGTATCTACTAGCATATCCACAAAAA CCCATGGTTAAGACAAAAACCATTGAATTGATAGAATTTGAGAAACTGCCAGCTGGACAGAATGCAACAGTTGCTGTGATGAGCTATAGT GGCTATGATATTGAAGATGCTCTTGTTTTAAACAAGGCCTCTTTAGACAGAGGCTTTGGGCGTTGCCTTGTATATAAAAATGCTAAATGT ACGTTGAAACGATACACCAATCAGACTTTTGATAAAGTGATGGGGCCCATGTTGGATGCTGCTACAAGGAAACCTATCTGGCGACATGAA ATCTTAGATGCAGATGGTATTTGTTCTCCAGGTGAGAAAGTAGAAAACAAACAAGTGCTTGTAAATAAGTCCATGCCCACAGTGACTCAG ATTCCTTTGGAAGGAAGTAATGTACCACAGCAACCACAGTACAAAGATGTACCCATAACCTACAAAGGAGCAACAGACTCATATATTGAA AAAGTGATGATATCTTCAAATGCTGAAGATGCTTTTCTGATCAAAATGCTGCTGAGACAGACAAGGCGTCCAGAAATTGGAGACAAATTC AGCAGTCGTCATGGGCAAAAAGGTGTTTGTGGCTTGATCGTCCCCCAGGAAGACATGCCATTTTGTGATTCTGGCATCTGTCCGGACATC ATCATGAACCCACACGGCTTCCCATCACGAATGACGGTGGGGAAGCTCATTGAGCTGCTGGCTGGCAAGGCCGGTGTGCTGGACGGCAGA TTCCACTACGGCACTGCGTTTGGAGGCAGTAAAGTGAAGGATGTGTGTGAGGACCTCGTTCGCCATGGTTATAACTACTTGGGGAAAGAC TATGTTACATCCGGCATCACAGGTGAGCCCTTAGAAGCATACATCTATTTTGGCCCCGTGTACTATCAGAAGCTGAAACACATGGTGCTA GATAAAATGCATGCCCGGGCCCGGGGCCCACGAGCCGTCCTTACCAGGCAACCCACTGAAGGACGGTCTCGTGATGGTGGCTTGCGTCTC GGGGAAATGGAACGTGACTGTTTAATCGGTTATGGAGCCAGTATGCTTTTGCTAGAGAGACTAATGATTTCAAGTGATGCCTTTGAGGTT GATGTCTGTGGGCAGTGTGGACTTCTGGGGTATTCTGGCTGGTGCCATTACTGCAAGTCATCCTGCCACGTGTCTTCCCTCCGTATTCCG TATGCCTGCAAGCTGCTCTTCCAGGAACTACAGTCTATGAACATCATCCCCAGGTTAAAACTGTCCAAGTACAATGAATGAGGATGGAAA AAATGATTATTAAAGAGAACAAGTGATACATCCAATGCAACGGAAAGCAGAAGGGATTTAGGACTACGTCTCCTCCTGTGAAGAATTCCC TTGCGTATTCTCTCTCTAAAACAACCAAAAAAAAATGGAGAGGCTTTTTATATACTCTAAGACTGGCTAAACAACCTTGATCATTGAGCC TCGAGCCATGGGAGAGATGCTGACCATGTGGACTGCAAGGCTGCTTGATTCACAGATGGATGTGACCTAAAGGATAAATAAGCTATTACT TATGTGCTGATCTCTTGACATTCACTCATTAGAAGACCTTACTCCTTCAAGCAAATGTTTGGGGTCAAATTTACCATATCTTCTGGCTAA CCATATTCAAGATTCTTCTGAAACTTGGAGGATGTAAAGAATCCATTTGATTTGGTCAGCCTGGCTTTTGTCGTGGTGGCTGGCTCGGAT AAATTTTCCCAACAATTAAATCTTGCCTTTACACACCCAAACTTTGTAATTTTAGTCTTGGTGAAATATAATGAATTTGTTCCTACCTTG TCAAGCAAGAATGTCGTCTTCTCCTATGGACTCAATTGCTATTATTTTAAACCTGCATGATTGTACCATGCAATACTATTCGTTAAATAT |
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FusionGenePPI for MDM2_POLR3B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MDM2 | TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2 | POLR3B | POLR3D, RAE1, POLR3H, GPN1, RPAP2, RPAP1, POLR3A, POLR2H, POLR1C, CRCP, POLR1D, TSR1, MOV10, NXF1, MAF1, GPN3, PIH1D1, PPP1CC, PPP1CA, SKAP1, EEF1A1, IPO9, MRPL17, NOB1, POLR1A, POLR1B, POLR2A, POLR2E, POLR3C, POLR3E, LOC101060521, POLR3F, POLR3G, POLR3K, RPL30, RRS1, SMARCA5, NTRK1, KRAS, GSK3A, POLR2F, MATR3, DSN1, POLR3GL, UXT, P4HA2, APOBEC3D, URI1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 170_306 | 306 | 498 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 150_230 | 245 | 437 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 150_230 | 306 | 498 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 223_232 | 245 | 437 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000462284 | + | 10 | 11 | 223_232 | 306 | 498 | USP7 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000258149 | + | 8 | 9 | 170_306 | 245 | 437 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 170_306 | 130 | 322 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 170_306 | 0 | 266 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 170_306 | 130 | 322 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 170_306 | 105 | 297 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 170_306 | -92 | 219 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 170_306 | 0 | 219 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 170_306 | -102 | 271 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 170_306 | 105 | 297 | MTBP |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 150_230 | 130 | 322 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 150_230 | 0 | 266 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 150_230 | 130 | 322 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 150_230 | 105 | 297 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 150_230 | -92 | 219 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 150_230 | 0 | 219 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 150_230 | -102 | 271 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 150_230 | 105 | 297 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000299252 | + | 4 | 5 | 223_232 | 130 | 322 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000348801 | + | 1 | 3 | 223_232 | 0 | 266 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000356290 | + | 5 | 6 | 223_232 | 130 | 322 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000360430 | + | 3 | 4 | 223_232 | 105 | 297 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393412 | + | 1 | 3 | 223_232 | -92 | 219 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000393413 | + | 1 | 2 | 223_232 | 0 | 219 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000428863 | + | 1 | 4 | 223_232 | -102 | 271 | USP7 |
| Hgene | MDM2 | chr12:69230529 | chr12:106820975 | ENST00000540827 | + | 4 | 5 | 223_232 | 105 | 297 | USP7 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MDM2_POLR3B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | MDM2 | Q00987 | DB01593 | Zinc | E3 ubiquitin-protein ligase Mdm2 | small molecule | approved|investigational |
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RelatedDiseases for MDM2_POLR3B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MDM2 | C0007131 | Non-Small Cell Lung Carcinoma | 2 | CTD_human |
| Hgene | MDM2 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Hgene | MDM2 | C0019693 | HIV Infections | 1 | CTD_human |
| Hgene | MDM2 | C0021364 | Male infertility | 1 | CTD_human |
| Hgene | MDM2 | C0025202 | melanoma | 1 | CTD_human |
| Hgene | MDM2 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Hgene | MDM2 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | MDM2 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Tgene | POLR3B | C3280644 | LEUKODYSTROPHY, HYPOMYELINATING, 8, WITH OR WITHOUT OLIGODONTIA AND/OR HYPOGONADOTROPIC HYPOGONADISM | 3 | UNIPROT |
| Tgene | POLR3B | C3714756 | Intellectual Disability | 1 | CTD_human |
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