	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
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Fusion gene ID: 21390

FusionGeneSummary for MDM2_NUP107

Fusion gene summary

Fusion gene information	Fusion gene name: MDM2_NUP107
	Fusion gene ID: 21390
		Hgene	Tgene
	Gene symbol	MDM2	NUP107
	Gene ID	4193	57122
	Gene name	MDM2 proto-oncogene	nucleoporin 107
	Synonyms	ACTFS\|HDMX\|hdm2	NPHS11\|NUP84
	Cytomap	12q15	12q15
	Type of gene	protein-coding	protein-coding
	Description	E3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, hum	nuclear pore complex protein Nup107nucleoporin 107kDa
	Modification date	20180527	20180523
	UniProtAcc	Q00987	P57740
	Ensembl transtripts involved in fusion gene	ENST00000462284, ENST00000356290, ENST00000540827, ENST00000258149, ENST00000428863, ENST00000393412, ENST00000258148, ENST00000544561, ENST00000393410, ENST00000393413, ENST00000517852, ENST00000545204, ENST00000350057, ENST00000360430, ENST00000299252, ENST00000348801, ENST00000478070, ENST00000544125,	ENST00000229179, ENST00000378905, ENST00000539906, ENST00000401003,
Fusion gene scores	* DoF score	24 X 14 X 8=2688	23 X 12 X 9=2484
	# samples	25	26
	** MAII score	log2(25/2688*10)=-3.42653313811667 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(26/2484*10)=-3.25608164519203 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MDM2 [Title/Abstract] AND NUP107 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation	Oncogene involved fusion gene, in-frame and retained their domain.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	MDM2	GO:0000122	negative regulation of transcription by RNA polymerase II	9271120\|17310983
Hgene	MDM2	GO:0006511	ubiquitin-dependent protein catabolic process	11278372\|15314173\|16173922\|17310983
Hgene	MDM2	GO:0016567	protein ubiquitination	9450543\|15878855\|19656744\|20153724
Hgene	MDM2	GO:0031648	protein destabilization	9529249\|10360174\|15314173
Hgene	MDM2	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	11278372
Hgene	MDM2	GO:0034504	protein localization to nucleus	10360174
Hgene	MDM2	GO:0042176	regulation of protein catabolic process	9153395
Hgene	MDM2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	9529249\|10360174
Hgene	MDM2	GO:0045184	establishment of protein localization	10360174
Hgene	MDM2	GO:0045892	negative regulation of transcription, DNA-templated	9271120
Hgene	MDM2	GO:0065003	protein-containing complex assembly	10608892\|12915590
Hgene	MDM2	GO:0071157	negative regulation of cell cycle arrest	9529249
Hgene	MDM2	GO:0071480	cellular response to gamma radiation	16213212
Hgene	MDM2	GO:0072717	cellular response to actinomycin D	15314173
Hgene	MDM2	GO:1901797	negative regulation of signal transduction by p53 class mediator	16173922
Tgene	NUP107	GO:0006406	mRNA export from nucleus	11684705

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	RV	BRCA	TCGA-3C-AAAU-01A	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
TCGA	RV	LUAD	TCGA-55-8085-01A	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
TCGA	RV	LUSC	TCGA-NC-A5HE-01A	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000462284	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000462284	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000462284	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000462284	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000356290	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000356290	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000356290	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000356290	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000540827	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000540827	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000540827	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000540827	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258149	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258149	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258149	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000258149	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000428863	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000428863	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000428863	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000428863	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393412	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393412	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393412	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000393412	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258148	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258148	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000258148	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000258148	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544561	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544561	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544561	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000544561	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393410	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393410	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393410	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000393410	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393413	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393413	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000393413	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000393413	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000517852	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000517852	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000517852	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000517852	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000545204	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000545204	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000545204	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000545204	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000350057	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000350057	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000350057	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000350057	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000360430	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000360430	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000360430	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000360430	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000299252	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000299252	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000299252	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000299252	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000348801	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000348801	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000348801	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
5CDS-intron	ENST00000348801	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000478070	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000478070	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000478070	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000478070	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544125	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544125	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-3CDS	ENST00000544125	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
intron-intron	ENST00000544125	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69113121	+
In-frame	ENST00000462284	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000462284	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000462284	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000462284	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000356290	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000356290	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000356290	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000356290	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000540827	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000540827	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000540827	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000540827	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258149	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258149	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258149	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000258149	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000428863	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000428863	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000428863	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000428863	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393412	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393412	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393412	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000393412	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258148	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258148	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000258148	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000258148	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544561	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544561	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544561	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000544561	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393410	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393410	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393410	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000393410	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393413	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393413	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000393413	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000393413	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000517852	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000517852	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000517852	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000517852	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000545204	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000545204	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000545204	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000545204	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000350057	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000350057	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000350057	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000350057	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000360430	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000360430	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000360430	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000360430	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000299252	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000299252	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000299252	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000299252	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000348801	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000348801	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000348801	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
5CDS-intron	ENST00000348801	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000478070	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000478070	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000478070	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000478070	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544125	ENST00000229179	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544125	ENST00000378905	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-3CDS	ENST00000544125	ENST00000539906	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
intron-intron	ENST00000544125	ENST00000401003	MDM2	chr12	69229764	+	NUP107	chr12	69135593	+
In-frame	ENST00000462284	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-5UTR	ENST00000462284	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-5UTR	ENST00000462284	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-intron	ENST00000462284	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-3CDS	ENST00000356290	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000356290	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000356290	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-intron	ENST00000356290	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-3CDS	ENST00000540827	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000540827	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000540827	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-intron	ENST00000540827	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-3CDS	ENST00000258149	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000258149	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000258149	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-intron	ENST00000258149	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-3CDS	ENST00000428863	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000428863	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000428863	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-intron	ENST00000428863	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-3CDS	ENST00000393412	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000393412	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-5UTR	ENST00000393412	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5UTR-intron	ENST00000393412	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
In-frame	ENST00000258148	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-5UTR	ENST00000258148	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-5UTR	ENST00000258148	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
5CDS-intron	ENST00000258148	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000544561	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000544561	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000544561	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000544561	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000393410	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000393410	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000393410	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000393410	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000393413	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000393413	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000393413	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000393413	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000517852	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000517852	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000517852	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000517852	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000545204	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000545204	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000545204	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000545204	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000350057	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000350057	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000350057	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000350057	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000360430	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000360430	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000360430	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000360430	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000299252	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000299252	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000299252	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000299252	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000348801	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000348801	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000348801	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000348801	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000478070	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000478070	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000478070	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000478070	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-3CDS	ENST00000544125	ENST00000229179	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000544125	ENST00000378905	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-5UTR	ENST00000544125	ENST00000539906	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+
intron-intron	ENST00000544125	ENST00000401003	MDM2	chr12	69202271	+	NUP107	chr12	69082742	+

Top

FusionProtFeatures for MDM2_NUP107

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MDM2 Q00987	NUP107 P57740
	Plays a role in the nuclear pore complex (NPC) assemblyand/or maintenance (PubMed:12552102, PubMed:15229283). Requiredfor the assembly of peripheral proteins into the NPC(PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC(PubMed:15229283). {ECO:0000269\|PubMed:12552102,ECO:0000269\|PubMed:15229283}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

210_215

219

437

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

210_215

280

498

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

210_215

219

437

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

210_215

280

498

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

27_107

219

437

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

27_107

104

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

27_107

104

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

27_107

280

498

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

27_107

219

437

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

27_107

104

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

27_107

104

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

27_107

280

498

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

179_185

219

437

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

190_202

219

437

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

179_185

280

498

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

190_202

280

498

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

179_185

219

437

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

190_202

219

437

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

179_185

280

498

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

190_202

280

498

Motif

Note=Nuclear export signal

- In-frame and not-retained protein feature among the 13 regional features.

>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

210_215

-2

437

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

243_301

-2

437

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

210_215

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

243_301

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

210_215

266

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

243_301

266

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

210_215

-2

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

243_301

-2

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

210_215

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

243_301

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

210_215

-2

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

243_301

-2

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

210_215

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

243_301

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

210_215

-2

271

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

243_301

-2

271

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

210_215

498

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

243_301

498

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

210_215

-2

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

243_301

-2

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

243_301

219

437

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

210_215

104

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

243_301

104

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

210_215

266

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

243_301

266

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

210_215

104

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

243_301

104

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

210_215

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

243_301

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

210_215

-92

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

243_301

-92

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

210_215

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

243_301

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

210_215

271

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

243_301

271

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

243_301

280

498

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

210_215

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

243_301

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

243_301

219

437

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

210_215

104

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

243_301

104

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

210_215

266

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

243_301

266

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

210_215

104

322

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

243_301

104

322

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

210_215

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

243_301

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

210_215

-92

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

243_301

-92

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

210_215

219

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

243_301

219

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

210_215

271

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

243_301

271

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

243_301

280

498

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

210_215

297

Compositional bias

Note=Poly-Ser

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

243_301

297

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

27_107

-2

437

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

27_107

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

27_107

266

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

27_107

-2

322

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

27_107

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

27_107

-2

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

27_107

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

27_107

-2

271

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

27_107

498

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

27_107

-2

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

27_107

266

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

27_107

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

27_107

-92

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

27_107

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

27_107

271

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

27_107

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

27_107

266

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

27_107

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

27_107

-92

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

27_107

219

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

27_107

271

Domain

Note=SWIB

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

27_107

297

Domain

Note=SWIB

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

179_185

-2

437

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

190_202

-2

437

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

466_473

-2

437

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

179_185

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

190_202

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

466_473

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

179_185

266

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

190_202

266

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

466_473

266

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

179_185

-2

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

190_202

-2

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

466_473

-2

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

179_185

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

190_202

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

466_473

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

179_185

-2

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

190_202

-2

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

466_473

-2

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

179_185

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

190_202

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

466_473

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

179_185

-2

271

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

190_202

-2

271

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

466_473

-2

271

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

179_185

498

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

190_202

498

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

466_473

498

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

179_185

-2

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

190_202

-2

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

466_473

-2

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

466_473

219

437

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

179_185

104

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

190_202

104

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

466_473

104

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

179_185

266

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

190_202

266

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

466_473

266

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

179_185

104

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

190_202

104

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

466_473

104

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

179_185

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

190_202

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

466_473

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

179_185

-92

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

190_202

-92

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

466_473

-92

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

179_185

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

190_202

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

466_473

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

179_185

271

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

190_202

271

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

466_473

271

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

466_473

280

498

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

179_185

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

190_202

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

466_473

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

466_473

219

437

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

179_185

104

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

190_202

104

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

466_473

104

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

179_185

266

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

190_202

266

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

466_473

266

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

179_185

104

322

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

190_202

104

322

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

466_473

104

322

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

179_185

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

190_202

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

466_473

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

179_185

-92

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

190_202

-92

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

466_473

-92

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

179_185

219

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

190_202

219

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

466_473

219

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

179_185

271

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

190_202

271

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

466_473

271

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

466_473

280

498

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

179_185

297

Motif

Nuclear localization signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

190_202

297

Motif

Note=Nuclear export signal

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

466_473

297

Motif

Nucleolar localization signal

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

210_304

-2

437

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

242_331

-2

437

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

210_304

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

242_331

322

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

210_304

266

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

242_331

266

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

210_304

-2

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

242_331

-2

322

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

210_304

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

242_331

297

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

210_304

-2

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

242_331

-2

219

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

210_304

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

242_331

219

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

210_304

-2

271

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

242_331

-2

271

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

210_304

498

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

242_331

498

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

210_304

-2

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

242_331

-2

297

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

210_304

219

437

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

242_331

219

437

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

210_304

104

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

242_331

104

322

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

210_304

266

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

242_331

266

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

210_304

104

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

242_331

104

322

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

210_304

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

242_331

297

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

210_304

-92

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

242_331

-92

219

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

210_304

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

242_331

219

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

210_304

271

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

242_331

271

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

210_304

280

498

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

242_331

280

498

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

210_304

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

242_331

297

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

210_304

219

437

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

242_331

219

437

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

210_304

104

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

242_331

104

322

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

210_304

266

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

242_331

266

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

210_304

104

322

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

242_331

104

322

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

210_304

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

242_331

297

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

210_304

-92

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

242_331

-92

219

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

210_304

219

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

242_331

219

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

210_304

271

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

242_331

271

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

210_304

280

498

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

242_331

280

498

Region

Note=Region II

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

210_304

297

Region

Note=ARF-binding

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

242_331

297

Region

Note=Region II

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

299_328

-2

437

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000258149

438_479

-2

437

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

299_328

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000299252

438_479

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

299_328

266

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000348801

438_479

266

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

299_328

-2

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000356290

438_479

-2

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

299_328

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000360430

438_479

297

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

299_328

-2

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393412

438_479

-2

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

299_328

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000393413

438_479

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

299_328

-2

271

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000428863

438_479

-2

271

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

299_328

498

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000462284

438_479

498

Zinc finger

RING-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

299_328

-2

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69202271

chr12:69082742

ENST00000540827

438_479

-2

297

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

299_328

219

437

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000258149

438_479

219

437

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

299_328

104

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000299252

438_479

104

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

299_328

266

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000348801

438_479

266

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

299_328

104

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000356290

438_479

104

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

299_328

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000360430

438_479

297

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

299_328

-92

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393412

438_479

-92

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

299_328

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000393413

438_479

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

299_328

271

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000428863

438_479

271

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

299_328

280

498

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000462284

438_479

280

498

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

299_328

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69113121

ENST00000540827

438_479

297

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

299_328

219

437

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000258149

438_479

219

437

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

299_328

104

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000299252

438_479

104

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

299_328

266

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000348801

438_479

266

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

299_328

104

322

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000356290

438_479

104

322

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

299_328

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000360430

438_479

297

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

299_328

-92

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393412

438_479

-92

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

299_328

219

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000393413

438_479

219

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

299_328

271

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000428863

438_479

271

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

299_328

280

498

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000462284

438_479

280

498

Zinc finger

RING-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

299_328

297

Zinc finger

RanBP2-type

Hgene

MDM2

chr12:69229764

chr12:69135593

ENST00000540827

438_479

297

Zinc finger

RING-type

Top

FusionGeneSequence for MDM2_NUP107

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_845aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHC
LELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEV
FVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGI
WKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLV

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_757aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAK
EVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDF
GIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLY

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_845aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHC
LELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEV
FVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGI
WKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLV

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_581aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKH
EAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKT
EMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSER

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_784aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFT
TCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDP
AQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQ
KPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLH

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_696aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVF
DPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSV
PQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFL

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_784aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFT
TCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDP
AQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQ
KPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLH

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_790aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHT
NLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVID
WLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKH
MNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPM

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_702aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDV
IDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWF
KHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCL

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_790aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHT
NLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVID
WLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKH
MNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPM

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_814aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFS
HHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDN
AIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDV
REDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGTE

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_726aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAED
DNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMV
DVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLG

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_814aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFS
HHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDN
AIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDV
REDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGTE

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_581aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKH
EAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKT
EMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSER

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_639aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKD
NGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLP
AEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGG
WMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLD

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_551aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESP
LPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVD
GGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQG

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_639aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKD
NGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLP
AEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGG
WMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLD

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_928aa
MVRSRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPR
LTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEETE
NICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLTRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQL
VVDWLESIAKDEIGEFSDNIEFTAKSVTWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKTLFTLIRAGM
TEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDT
VWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKS
RNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEA
DLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQD
SIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDA
LTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELR

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_928aa
MVRSRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPR
LTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEETE
NICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLTRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQL
VVDWLESIAKDEIGEFSDNIEFTAKSVTWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKTLFTLIRAGM
TEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDT
VWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKS
RNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEA
DLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQD
SIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDA
LTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELR

* Fusion transcript sequences (only coding sequence (CDS) region).

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2535nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTT
TATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGC
CTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTT
AGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGAC
CCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTA
TTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGAT
AATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCA
CAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATT
TGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGAT
GTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTT
CATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTA
TTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTAT

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2271nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTA
TTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAA
GAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAA
GATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCA
GTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTT
GGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATG
GTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTT
CTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTAC
CTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTA

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2535nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTT
TATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGC
CTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTT
AGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGAC
CCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTA
TTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGAT
AATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCA
CAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATT
TGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGAT
GTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTT
CATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTA
TTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTAT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1743nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2352nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2088nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2352nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2370nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACA
AATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAA
CAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAA
GATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGAC
TGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAA
GCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTT
CCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCAT
ATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAA
ATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGA
GGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATG
TTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCAC
AAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2106nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTA
ATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAG
CACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGT
CCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTT
AAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAA
TATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTT
GATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTG
CCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAG
CGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAG

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2370nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACA
AATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAA
CAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAA
GATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGAC
TGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAA
GCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTT
CCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCAT
ATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAA
ATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGA
GGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATG
TTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCAC
AAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2442nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2178nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2442nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1743nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1917nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1653nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1917nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_2784nt
ATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCACGGAAACAGAGTGCT
CAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTCGAACTCCTAGCTCA
TTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAGGGAAGTCGCCCCGA
CTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCATTTTCATCACAGCGT
TCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGGATGATCCTGGAGAA
GCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTGTGGAAGAGTATGAA
AACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAAAAACAGCCAGTATG
CTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCATTAGAAGAGGAAAGT
GTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTCGACAAAGTCAGCTG
GTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAATCAGTATATTGGGAA
AATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGGACCCTGATGCTCCC
ATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAATCCGTGCTGGAATG
ACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAAT
GTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAG
CTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACA
GTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTC
CCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAAT
CAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGC
AGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTT
TCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAA
GACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCA
GATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCA
GCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCA
CTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGAT
TCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTG
TGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCT
CAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCC
CTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAA
GACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACT
GGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGG

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_2784nt
ATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCACGGAAACAGAGTGCT
CAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTCGAACTCCTAGCTCA
TTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAGGGAAGTCGCCCCGA
CTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCATTTTCATCACAGCGT
TCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGGATGATCCTGGAGAA
GCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTGTGGAAGAGTATGAA
AACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAAAAACAGCCAGTATG
CTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCATTAGAAGAGGAAAGT
GTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTCGACAAAGTCAGCTG
GTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAATCAGTATATTGGGAA
AATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGGACCCTGATGCTCCC
ATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAATCCGTGCTGGAATG
ACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAAT
GTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAG
CTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACA
GTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTC
CCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAAT
CAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGC
AGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTT
TCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAA
GACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCA
GATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCA
GCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCA
CTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGAT
TCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTG
TGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCT
CAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCC
CTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAA
GACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACT
GGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGG

* Fusion transcript sequences (Full-length transcript).

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_3380nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT
TTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATT
ATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTAC
AAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTA
AAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAA
AATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTC

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2794nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATC
GTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAAT
TCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGG
AACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAA
CCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATG
AACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATA
ACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTAC
TGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAG
ATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTC
TAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAAT
GAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAG
AATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGT

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2906nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2855nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATG
CATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAA
CAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTG
AGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTA
TGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATC
AGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAG
CCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAG
TGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGA
AAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAA
TGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTAC
AGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAG
AGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTC
ATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGT
ACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAA
ATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAG
CATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGT
ATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2269nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATG
CAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCT
ATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATT
TGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTG
AGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGA
AGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACAC
ATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAAT
GCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGC
TCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTA
ATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAA
TTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAA

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2381nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATG
CATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAA
CAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTG
AGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTA
TGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATC
AGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAG
CCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAG
TGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGA
AAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAA
TGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTAC
AGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAG
AGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTC

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2780nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA
ATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAG
ACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAAC
TATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTT
TTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTT
ATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGT

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2194nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCAC
TGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATT
CTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGT
GCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTC
AACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCC
TAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAG
ACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTG
GTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGA
AGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATC
TTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAA
ATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAA

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2306nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_3200nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT
TTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATT
ATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTAC
AAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTA
AAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAA
AATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTC

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2614nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATC
GTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAAT
TCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGG
AACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAA
CCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATG
AACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATA
ACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTAC
TGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAG
ATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTC
TAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAAT
GAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAG
AATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGT

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2726nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2780nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA
ATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAG
ACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAAC
TATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTT
TTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTT
ATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGT

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2194nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCAC
TGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATT
CTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGT
GCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTC
AACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCC
TAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAG
ACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTG
GTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGA
AGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATC
TTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAA
ATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2306nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2927nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAA
GAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTG
TTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGA
ATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAA
TTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCAT
CAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAA
TGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATG
AGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAG
AAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGT
TGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGC
TTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTAT
CCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCC
TAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTT
AATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATC
GTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAA
TTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAA
TCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAAT
TAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2341nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTT
TAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCT
TGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAAC
AAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCT
TTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAAC
ACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACG
TCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGA
GAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATA
TGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAA
TGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAA
GTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAAT
ATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2453nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAA
GAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTG
TTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGA
ATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAA
TTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCAT
CAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAA
TGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATG
AGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAG
AAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGT
TGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGC
TTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTAT
CCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCC
TAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2985nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA
ATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTC
TTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGT
TTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGA
AAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTT
AAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAA
CATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAAAATAAGAGCATATA

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2399nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG
TATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAAT
TTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATAT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2511nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2475nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA
GACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAA
TAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGT
GACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATT
CCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATC
ATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTA
AGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1889nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG
CTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGT
TTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATAT

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2001nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA
GACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2550nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT
ATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATG
TAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTT
TTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAA
AGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAA
CAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1964nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA
CTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATA
CTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTC

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2076nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2460nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT
ATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATG
TAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTT
TTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAA
AGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAA
CAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCA

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1874nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA
CTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATA
CTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1986nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_3629nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAG
AGGTGACACGGACTGCACGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAA
GAAACCAGGTTATCCCTCGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCT
GCATTCTTGGAACAGGAGGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACA
GTAACTGGGCAGCTGCATTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTG
CTGTTATGTTACGTGAGGATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGA
GTACAGTTTTTGATCTTGTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTG
GACTTCAAAAATTTTCAAAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAG
ACAGAATACAGTCTGCATTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTC
AGAGGGATTCACTTGTTCGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATA
TTGAGTTTTATGCAAAATCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTC
CGCTTGTCACTGAATTGGACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCA
AATATCTCTTTACTCTAATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACAC
TTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGA
AAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGC
TGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACAT
CAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAG
CTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGA
TGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCC
GTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATC
TTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGC
GCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATA
ATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGT
TGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTG
CAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTG
CTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGA
ATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGG
ATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGT
GGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGT
GTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAAC
TGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACC
CATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTA
TTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGT
AGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTT
TTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAA
GTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAAC
AAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAA

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_3341nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCAC
GGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTC
GAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAG
GGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCAT
TTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGG
ATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTG
TGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAA
AAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCAT
TAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTC
GACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAAT
CAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGG
ACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAA
TCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGT
ACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAA
TGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACA
CCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATG
AAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAG
TTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAAT
GGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGA
CCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCT
GTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGT
TGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATC
ATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGC
AGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGA
AAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTA
TCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAAC
CTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAG
GGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAG
AGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGA
TATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTA
AGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTC
AGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTT
GCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCT
CTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAAT
TAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGC
CAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATA
ACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAAAATAAGAGCATATAAAGA

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FusionGenePPI for MDM2_NUP107

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene	Hgene's interactors	Tgene	Tgene's interactors
MDM2	TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2	NUP107	SEH1L, NUP133, NUP85, NUP160, NUP43, NUP37, SEC13, TPR, NUP214, KPNB1, SIRT7, NUP98, WRNIP1, CUL3, CENPF, NUP153, TP53BP1, PNPT1, EIF4B, CORO1B, MYL1, C1QBP, CPSF6, VCP, PYCARD, CUL7, OBSL1, SUZ12, EED, PNKD, NTRK1, IFI16, SYNE1, APC, PRKDC, RRP1B, NALCN, CD1E, ACTBL2, HSP90AB1, XPO1, SENP1, SENP2, AHCTF1, RANGAP1, H2AFV, NUP50, RANBP2, B9D2, ACLY, RCC1, GLE1, ITPR2, KPNA4, NUP88, RAN, UBE2I, SUMO1, AAAS, RAE1, NUP155, NUP93, NUPL1, WDR1, NXF1, IPO7, NUPL2, NUP205, NUP210, NUP188, NUP62, NXT1, SEC61A1, NUP54, TMEM214, SMPD4, NDC1, KRAS, IP6K3, TMEM209, NUP35, RPUSD3, RGPD8, POM121C, FOXA3, FOXI2, FOXK2, FOXL1, FOXP3, FOXQ1, CDC5L, ZNF746, DUSP13, SPAST, UXS1, SIGLECL1, CD70, RAF1, PDHA1, TRIM25, BRCA1

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000462284	+	9	11	150_230	280	498	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000462284	+	9	11	150_230	280	498	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000462284	+	9	11	223_232	280	498	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000462284	+	9	11	223_232	280	498	USP7

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000258149	+	1	9	170_306	-2	437	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000299252	+	1	5	170_306	0	322	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000348801	+	1	3	170_306	0	266	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000356290	+	1	6	170_306	-2	322	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000360430	+	1	4	170_306	0	297	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393412	+	1	3	170_306	-2	219	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393413	+	1	2	170_306	0	219	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000428863	+	1	4	170_306	-2	271	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000462284	+	1	11	170_306	4	498	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000540827	+	1	5	170_306	-2	297	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000258149	+	7	9	170_306	219	437	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000299252	+	3	5	170_306	104	322	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000348801	+	2	3	170_306	74	266	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000356290	+	4	6	170_306	104	322	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000360430	+	2	4	170_306	79	297	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393412	+	1	3	170_306	-92	219	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393413	+	1	2	170_306	0	219	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000428863	+	3	4	170_306	79	271	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000462284	+	9	11	170_306	280	498	MTBP
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000540827	+	3	5	170_306	79	297	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000258149	+	7	9	170_306	219	437	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000299252	+	3	5	170_306	104	322	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000348801	+	2	3	170_306	74	266	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000356290	+	4	6	170_306	104	322	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000360430	+	2	4	170_306	79	297	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393412	+	1	3	170_306	-92	219	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393413	+	1	2	170_306	0	219	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000428863	+	3	4	170_306	79	271	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000462284	+	9	11	170_306	280	498	MTBP
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000540827	+	3	5	170_306	79	297	MTBP
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000258149	+	1	9	150_230	-2	437	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000299252	+	1	5	150_230	0	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000348801	+	1	3	150_230	0	266	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000356290	+	1	6	150_230	-2	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000360430	+	1	4	150_230	0	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393412	+	1	3	150_230	-2	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393413	+	1	2	150_230	0	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000428863	+	1	4	150_230	-2	271	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000462284	+	1	11	150_230	4	498	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000540827	+	1	5	150_230	-2	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000258149	+	7	9	150_230	219	437	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000299252	+	3	5	150_230	104	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000348801	+	2	3	150_230	74	266	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000356290	+	4	6	150_230	104	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000360430	+	2	4	150_230	79	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393412	+	1	3	150_230	-92	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393413	+	1	2	150_230	0	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000428863	+	3	4	150_230	79	271	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000540827	+	3	5	150_230	79	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000258149	+	7	9	150_230	219	437	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000299252	+	3	5	150_230	104	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000348801	+	2	3	150_230	74	266	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000356290	+	4	6	150_230	104	322	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000360430	+	2	4	150_230	79	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393412	+	1	3	150_230	-92	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393413	+	1	2	150_230	0	219	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000428863	+	3	4	150_230	79	271	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000540827	+	3	5	150_230	79	297	PYHIN1 and necessary for interaction with RFFL and RNF34
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000258149	+	1	9	223_232	-2	437	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000299252	+	1	5	223_232	0	322	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000348801	+	1	3	223_232	0	266	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000356290	+	1	6	223_232	-2	322	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000360430	+	1	4	223_232	0	297	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393412	+	1	3	223_232	-2	219	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000393413	+	1	2	223_232	0	219	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000428863	+	1	4	223_232	-2	271	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000462284	+	1	11	223_232	4	498	USP7
Hgene	MDM2	chr12:69202271	chr12:69082742	ENST00000540827	+	1	5	223_232	-2	297	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000258149	+	7	9	223_232	219	437	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000299252	+	3	5	223_232	104	322	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000348801	+	2	3	223_232	74	266	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000356290	+	4	6	223_232	104	322	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000360430	+	2	4	223_232	79	297	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393412	+	1	3	223_232	-92	219	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000393413	+	1	2	223_232	0	219	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000428863	+	3	4	223_232	79	271	USP7
Hgene	MDM2	chr12:69229764	chr12:69113121	ENST00000540827	+	3	5	223_232	79	297	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000258149	+	7	9	223_232	219	437	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000299252	+	3	5	223_232	104	322	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000348801	+	2	3	223_232	74	266	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000356290	+	4	6	223_232	104	322	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000360430	+	2	4	223_232	79	297	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393412	+	1	3	223_232	-92	219	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000393413	+	1	2	223_232	0	219	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000428863	+	3	4	223_232	79	271	USP7
Hgene	MDM2	chr12:69229764	chr12:69135593	ENST00000540827	+	3	5	223_232	79	297	USP7

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for MDM2_NUP107

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Hgene	MDM2	Q00987	DB01593	Zinc	E3 ubiquitin-protein ligase Mdm2	small molecule	approved\|investigational

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RelatedDiseases for MDM2_NUP107

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	MDM2	C0007131	Non-Small Cell Lung Carcinoma	2	CTD_human
Hgene	MDM2	C0007621	Neoplastic Cell Transformation	1	CTD_human
Hgene	MDM2	C0019693	HIV Infections	1	CTD_human
Hgene	MDM2	C0021364	Male infertility	1	CTD_human
Hgene	MDM2	C0025202	melanoma	1	CTD_human
Hgene	MDM2	C0032927	Precancerous Conditions	1	CTD_human
Hgene	MDM2	C0033578	Prostatic Neoplasms	1	CTD_human
Hgene	MDM2	C1458155	Mammary Neoplasms	1	CTD_human
Tgene	NUP107	C4225228	NEPHROTIC SYNDROME, TYPE 11	1	UNIPROT

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Fusion gene ID: 21390

FusionGeneSummary for MDM2_NUP107

FusionProtFeatures for MDM2_NUP107

FusionGeneSequence for MDM2_NUP107

FusionGenePPI for MDM2_NUP107

RelatedDrugs for MDM2_NUP107

RelatedDiseases for MDM2_NUP107