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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 21390

FusionGeneSummary for MDM2_NUP107

check button Fusion gene summary
Fusion gene informationFusion gene name: MDM2_NUP107
Fusion gene ID: 21390
HgeneTgene
Gene symbol

MDM2

NUP107

Gene ID

4193

57122

Gene nameMDM2 proto-oncogenenucleoporin 107
SynonymsACTFS|HDMX|hdm2NPHS11|NUP84
Cytomap

12q15

12q15

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, humnuclear pore complex protein Nup107nucleoporin 107kDa
Modification date2018052720180523
UniProtAcc

Q00987

P57740

Ensembl transtripts involved in fusion geneENST00000462284, ENST00000356290, 
ENST00000540827, ENST00000258149, 
ENST00000428863, ENST00000393412, 
ENST00000258148, ENST00000544561, 
ENST00000393410, ENST00000393413, 
ENST00000517852, ENST00000545204, 
ENST00000350057, ENST00000360430, 
ENST00000299252, ENST00000348801, 
ENST00000478070, ENST00000544125, 
ENST00000229179, ENST00000378905, 
ENST00000539906, ENST00000401003, 
Fusion gene scores* DoF score24 X 14 X 8=268823 X 12 X 9=2484
# samples 2526
** MAII scorelog2(25/2688*10)=-3.42653313811667
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(26/2484*10)=-3.25608164519203
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MDM2 [Title/Abstract] AND NUP107 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMDM2

GO:0000122

negative regulation of transcription by RNA polymerase II

9271120|17310983

HgeneMDM2

GO:0006511

ubiquitin-dependent protein catabolic process

11278372|15314173|16173922|17310983

HgeneMDM2

GO:0016567

protein ubiquitination

9450543|15878855|19656744|20153724

HgeneMDM2

GO:0031648

protein destabilization

9529249|10360174|15314173

HgeneMDM2

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

11278372

HgeneMDM2

GO:0034504

protein localization to nucleus

10360174

HgeneMDM2

GO:0042176

regulation of protein catabolic process

9153395

HgeneMDM2

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

9529249|10360174

HgeneMDM2

GO:0045184

establishment of protein localization

10360174

HgeneMDM2

GO:0045892

negative regulation of transcription, DNA-templated

9271120

HgeneMDM2

GO:0065003

protein-containing complex assembly

10608892|12915590

HgeneMDM2

GO:0071157

negative regulation of cell cycle arrest

9529249

HgeneMDM2

GO:0071480

cellular response to gamma radiation

16213212

HgeneMDM2

GO:0072717

cellular response to actinomycin D

15314173

HgeneMDM2

GO:1901797

negative regulation of signal transduction by p53 class mediator

16173922

TgeneNUP107

GO:0006406

mRNA export from nucleus

11684705


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-3C-AAAU-01AMDM2chr12

69229764

+NUP107chr12

69113121

+
TCGARVLUADTCGA-55-8085-01AMDM2chr12

69229764

+NUP107chr12

69135593

+
TCGARVLUSCTCGA-NC-A5HE-01AMDM2chr12

69202271

+NUP107chr12

69082742

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000462284ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000462284ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000462284ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000462284ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000356290ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000356290ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000356290ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000356290ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000540827ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000540827ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000540827ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000540827ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258149ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258149ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258149ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000258149ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000428863ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000428863ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000428863ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000428863ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393412ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393412ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393412ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000393412ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258148ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258148ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000258148ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000258148ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544561ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544561ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544561ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000544561ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393410ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393410ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393410ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000393410ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393413ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393413ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000393413ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000393413ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000517852ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000517852ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000517852ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000517852ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000545204ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000545204ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000545204ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000545204ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000350057ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000350057ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000350057ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000350057ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000360430ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000360430ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000360430ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000360430ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000299252ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000299252ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000299252ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000299252ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000348801ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000348801ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000348801ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
5CDS-intronENST00000348801ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000478070ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000478070ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000478070ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000478070ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544125ENST00000229179MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544125ENST00000378905MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-3CDSENST00000544125ENST00000539906MDM2chr12

69229764

+NUP107chr12

69113121

+
intron-intronENST00000544125ENST00000401003MDM2chr12

69229764

+NUP107chr12

69113121

+
In-frameENST00000462284ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000462284ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000462284ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000462284ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000356290ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000356290ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000356290ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000356290ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000540827ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000540827ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000540827ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000540827ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258149ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258149ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258149ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000258149ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000428863ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000428863ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000428863ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000428863ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393412ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393412ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393412ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000393412ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258148ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258148ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000258148ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000258148ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544561ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544561ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544561ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000544561ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393410ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393410ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393410ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000393410ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393413ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393413ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000393413ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000393413ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000517852ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000517852ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000517852ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000517852ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000545204ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000545204ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000545204ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000545204ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000350057ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000350057ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000350057ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000350057ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000360430ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000360430ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000360430ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000360430ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000299252ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000299252ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000299252ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000299252ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000348801ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000348801ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000348801ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
5CDS-intronENST00000348801ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000478070ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000478070ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000478070ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000478070ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544125ENST00000229179MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544125ENST00000378905MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-3CDSENST00000544125ENST00000539906MDM2chr12

69229764

+NUP107chr12

69135593

+
intron-intronENST00000544125ENST00000401003MDM2chr12

69229764

+NUP107chr12

69135593

+
In-frameENST00000462284ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-5UTRENST00000462284ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-5UTRENST00000462284ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-intronENST00000462284ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-3CDSENST00000356290ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000356290ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000356290ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-intronENST00000356290ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-3CDSENST00000540827ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000540827ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000540827ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-intronENST00000540827ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-3CDSENST00000258149ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000258149ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000258149ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-intronENST00000258149ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-3CDSENST00000428863ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000428863ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000428863ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-intronENST00000428863ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-3CDSENST00000393412ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000393412ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-5UTRENST00000393412ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5UTR-intronENST00000393412ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
In-frameENST00000258148ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-5UTRENST00000258148ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-5UTRENST00000258148ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
5CDS-intronENST00000258148ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000544561ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000544561ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000544561ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000544561ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000393410ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000393410ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000393410ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000393410ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000393413ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000393413ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000393413ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000393413ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000517852ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000517852ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000517852ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000517852ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000545204ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000545204ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000545204ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000545204ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000350057ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000350057ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000350057ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000350057ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000360430ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000360430ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000360430ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000360430ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000299252ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000299252ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000299252ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000299252ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000348801ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000348801ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000348801ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000348801ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000478070ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000478070ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000478070ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000478070ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-3CDSENST00000544125ENST00000229179MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000544125ENST00000378905MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-5UTRENST00000544125ENST00000539906MDM2chr12

69202271

+NUP107chr12

69082742

+
intron-intronENST00000544125ENST00000401003MDM2chr12

69202271

+NUP107chr12

69082742

+

Top

FusionProtFeatures for MDM2_NUP107


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MDM2

Q00987

NUP107

P57740

Plays a role in the nuclear pore complex (NPC) assemblyand/or maintenance (PubMed:12552102, PubMed:15229283). Requiredfor the assembly of peripheral proteins into the NPC(PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC(PubMed:15229283). {ECO:0000269|PubMed:12552102,ECO:0000269|PubMed:15229283}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79210_215219437Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911210_215280498Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79210_215219437Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911210_215280498Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+7927_107219437DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+3527_107104322DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+4627_107104322DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+91127_107280498DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+7927_107219437DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+3527_107104322DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+4627_107104322DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+91127_107280498DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79179_185219437MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79190_202219437MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911179_185280498MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911190_202280498MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79179_185219437MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79190_202219437MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911179_185280498MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911190_202280498MotifNote=Nuclear export signal

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19210_215-2437Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19243_301-2437Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15210_2150322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15243_3010322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13210_2150266Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13243_3010266Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16210_215-2322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16243_301-2322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14210_2150297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14243_3010297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13210_215-2219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13243_301-2219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12210_2150219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12243_3010219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14210_215-2271Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14243_301-2271Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111210_2154498Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111243_3014498Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15210_215-2297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15243_301-2297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79243_301219437Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35210_215104322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35243_301104322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23210_21574266Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23243_30174266Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46210_215104322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46243_301104322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24210_21579297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24243_30179297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13210_215-92219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13243_301-92219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12210_2150219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12243_3010219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34210_21579271Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34243_30179271Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911243_301280498Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35210_21579297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35243_30179297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79243_301219437Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35210_215104322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35243_301104322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23210_21574266Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23243_30174266Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46210_215104322Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46243_301104322Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24210_21579297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24243_30179297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13210_215-92219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13243_301-92219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12210_2150219Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12243_3010219Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34210_21579271Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34243_30179271Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911243_301280498Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35210_21579297Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35243_30179297Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+1927_107-2437DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+1527_1070322DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+1327_1070266DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+1627_107-2322DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+1427_1070297DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+1327_107-2219DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+1227_1070219DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+1427_107-2271DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+11127_1074498DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+1527_107-2297DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+2327_10774266DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+2427_10779297DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+1327_107-92219DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+1227_1070219DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+3427_10779271DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+3527_10779297DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+2327_10774266DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+2427_10779297DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+1327_107-92219DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+1227_1070219DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+3427_10779271DomainNote=SWIB
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+3527_10779297DomainNote=SWIB
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19179_185-2437MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19190_202-2437MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19466_473-2437MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15179_1850322MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15190_2020322MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15466_4730322MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13179_1850266MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13190_2020266MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13466_4730266MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16179_185-2322MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16190_202-2322MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16466_473-2322MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14179_1850297MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14190_2020297MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14466_4730297MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13179_185-2219MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13190_202-2219MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13466_473-2219MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12179_1850219MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12190_2020219MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12466_4730219MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14179_185-2271MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14190_202-2271MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14466_473-2271MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111179_1854498MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111190_2024498MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111466_4734498MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15179_185-2297MotifNuclear localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15190_202-2297MotifNote=Nuclear export signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15466_473-2297MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79466_473219437MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35179_185104322MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35190_202104322MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35466_473104322MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23179_18574266MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23190_20274266MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23466_47374266MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46179_185104322MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46190_202104322MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46466_473104322MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24179_18579297MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24190_20279297MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24466_47379297MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13179_185-92219MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13190_202-92219MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13466_473-92219MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12179_1850219MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12190_2020219MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12466_4730219MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34179_18579271MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34190_20279271MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34466_47379271MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911466_473280498MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35179_18579297MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35190_20279297MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35466_47379297MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79466_473219437MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35179_185104322MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35190_202104322MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35466_473104322MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23179_18574266MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23190_20274266MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23466_47374266MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46179_185104322MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46190_202104322MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46466_473104322MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24179_18579297MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24190_20279297MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24466_47379297MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13179_185-92219MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13190_202-92219MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13466_473-92219MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12179_1850219MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12190_2020219MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12466_4730219MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34179_18579271MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34190_20279271MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34466_47379271MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911466_473280498MotifNucleolar localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35179_18579297MotifNuclear localization signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35190_20279297MotifNote=Nuclear export signal
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35466_47379297MotifNucleolar localization signal
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19210_304-2437RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19242_331-2437RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15210_3040322RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15242_3310322RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13210_3040266RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13242_3310266RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16210_304-2322RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16242_331-2322RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14210_3040297RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14242_3310297RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13210_304-2219RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13242_331-2219RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12210_3040219RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12242_3310219RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14210_304-2271RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14242_331-2271RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111210_3044498RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111242_3314498RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15210_304-2297RegionNote=ARF-binding
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15242_331-2297RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79210_304219437RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79242_331219437RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35210_304104322RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35242_331104322RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23210_30474266RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23242_33174266RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46210_304104322RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46242_331104322RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24210_30479297RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24242_33179297RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13210_304-92219RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13242_331-92219RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12210_3040219RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12242_3310219RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34210_30479271RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34242_33179271RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911210_304280498RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911242_331280498RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35210_30479297RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35242_33179297RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79210_304219437RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79242_331219437RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35210_304104322RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35242_331104322RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23210_30474266RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23242_33174266RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46210_304104322RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46242_331104322RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24210_30479297RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24242_33179297RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13210_304-92219RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13242_331-92219RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12210_3040219RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12242_3310219RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34210_30479271RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34242_33179271RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911210_304280498RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911242_331280498RegionNote=Region II
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35210_30479297RegionNote=ARF-binding
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35242_33179297RegionNote=Region II
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19299_328-2437Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19438_479-2437Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15299_3280322Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15438_4790322Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13299_3280266Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13438_4790266Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16299_328-2322Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16438_479-2322Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14299_3280297Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14438_4790297Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13299_328-2219Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13438_479-2219Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12299_3280219Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12438_4790219Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14299_328-2271Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14438_479-2271Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111299_3284498Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111438_4794498Zinc fingerRING-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15299_328-2297Zinc fingerRanBP2-type
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15438_479-2297Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79299_328219437Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79438_479219437Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35299_328104322Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35438_479104322Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23299_32874266Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23438_47974266Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46299_328104322Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46438_479104322Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24299_32879297Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24438_47979297Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13299_328-92219Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13438_479-92219Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12299_3280219Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12438_4790219Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34299_32879271Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34438_47979271Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911299_328280498Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911438_479280498Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35299_32879297Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35438_47979297Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79299_328219437Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79438_479219437Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35299_328104322Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35438_479104322Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23299_32874266Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23438_47974266Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46299_328104322Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46438_479104322Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24299_32879297Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24438_47979297Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13299_328-92219Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13438_479-92219Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12299_3280219Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12438_4790219Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34299_32879271Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34438_47979271Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911299_328280498Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911438_479280498Zinc fingerRING-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35299_32879297Zinc fingerRanBP2-type
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35438_47979297Zinc fingerRING-type


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FusionGeneSequence for MDM2_NUP107


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_845aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHC
LELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEV
FVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGI
WKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLV

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_757aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAK
EVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDF
GIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLY

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_845aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEE
GQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPV
CDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEF
SKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHC
LELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEV
FVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGI
WKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLV

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_581aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKH
EAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKT
EMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSER

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_784aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFT
TCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDP
AQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQ
KPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLH

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_696aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVF
DPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSV
PQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFL

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_784aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPS
FSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW
LDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCW
RMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKK
RVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFT
TCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDP
AQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQ
KPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLH

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_790aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHT
NLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVID
WLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKH
MNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPM

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_702aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDV
IDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWF
KHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCL

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_790aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGD
LFGVPSFSVKEHRKITTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
EHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRI
WKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEEL
QATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHT
NLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVID
WLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKH
MNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPM

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_814aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFS
HHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDN
AIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDV
REDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGTE

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_726aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAED
DNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMV
DVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLG

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_814aa
MCNTNMSVPTDGAVTTSQIPASEQETLVLFTLGQTIMTKRLTDEKQQHIVTCSNDLLGDLFGVPSFSVKEHRKITTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI
CCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWK
LYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATL
DETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGL
QTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFS
HHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDN
AIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDV
REDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGTE

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_556aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQ
GMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNV
LLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLM

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_644aa
MCNTNMSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQA
WRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVE
QEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTH
LILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVEN
IRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGM
ESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLL
FVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLL

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_581aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKH
EAAKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKT
EMDFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSER

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_669aa
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTTTMKEDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTS
LSEEGQELSDEDDEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQ
LLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGL
MDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQ
RHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEA
AKEVFVKIPQDSIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEM
DFGIWKGHLDALTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHK

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_639aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKD
NGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLP
AEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGG
WMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLD

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_551aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESP
LPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVD
GGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQG

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_639aa
MSVPTDGAVTTSQIPASEQETLDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDTSLSEEGQELSDEDDEAQRLCKRCGQAWRAAT
LEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQT
SVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFF
RTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKD
NGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEITNQCEEQGMESPLP
AEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDALTADVKEKMTNVLLFVDGG
WMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLD

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_928aa
MVRSRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPR
LTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEETE
NICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLTRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQL
VVDWLESIAKDEIGEFSDNIEFTAKSVTWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKTLFTLIRAGM
TEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDT
VWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKS
RNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEA
DLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQD
SIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDA
LTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELR

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_928aa
MVRSRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPR
LTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEETE
NICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLTRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQL
VVDWLESIAKDEIGEFSDNIEFTAKSVTWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKTLFTLIRAGM
TEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPTRRIWKISCWRMAEDELFNRYERAITAALSGNLKQLLPVCDTWEDT
VWAYFRVMVDSLVEQEIQTSVATLDETEELPRETLGANWTLEKVFEELQATDKKRVLEENQEHTHIVQKFLILGDIDGLMDEFSKWLSKS
RNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFTTCHLPQDLAVAQTALFLESVTEFEQRHHCLELAKEA
DLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQD
SIAEITNQCEEQGMESPLPAEDDNAIREHLCIRATLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKTEMDFGIWKGHLDA
LTADVKEKMTNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQTQECLQLADMVSSERHKLYLVFSKEELR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2535nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTT
TATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGC
CTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTT
AGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGAC
CCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTA
TTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGAT
AATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCA
CAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATT
TGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGAT
GTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTT
CATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTA
TTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTAT

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2271nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTA
TTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAA
GAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAA
GATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCA
GTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTT
GGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATG
GTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTT
CTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTAC
CTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTA

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2535nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
TCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAA
GAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAA
TTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAG
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGAT
TGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAA
GGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGG
AAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGC
TGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTC
TGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACT
CTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAA
AAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTT
AGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGA
CTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTT
TATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGC
CTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTT
AGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGAC
CCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTA
TTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGAT
AATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCA
CAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATT
TGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGAT
GTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTT
CATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTA
TTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTAT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1743nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2352nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2088nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2352nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT
ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC
TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2370nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACA
AATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAA
CAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAA
GATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGAC
TGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAA
GCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTT
CCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCAT
ATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAA
ATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGA
GGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATG
TTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCAC
AAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2106nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTA
ATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAG
CACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGT
CCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTT
AAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAA
TATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTT
GATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTG
CCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAG
CGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAG

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2370nt
ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA
GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT
TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT
TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAA
GAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTG
TGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGT
GAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTAT
AGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCA
ACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATT
TGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAG
CAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAG
ACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTT
CAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGT
TTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTT
TTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACA
AATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAA
CAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAA
GATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGAC
TGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAA
GCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTT
CCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCAT
ATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAA
ATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGA
GGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATG
TTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCAC
AAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2442nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2178nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2442nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1668nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1932nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1743nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2007nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_1917nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1653nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1917nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_2784nt
ATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCACGGAAACAGAGTGCT
CAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTCGAACTCCTAGCTCA
TTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAGGGAAGTCGCCCCGA
CTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCATTTTCATCACAGCGT
TCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGGATGATCCTGGAGAA
GCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTGTGGAAGAGTATGAA
AACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAAAAACAGCCAGTATG
CTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCATTAGAAGAGGAAAGT
GTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTCGACAAAGTCAGCTG
GTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAATCAGTATATTGGGAA
AATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGGACCCTGATGCTCCC
ATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAATCCGTGCTGGAATG
ACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAAT
GTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAG
CTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACA
GTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTC
CCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAAT
CAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGC
AGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTT
TCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAA
GACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCA
GATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCA
GCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCA
CTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGAT
TCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTG
TGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCT
CAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCC
CTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAA
GACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACT
GGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGG

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_2784nt
ATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCACGGAAACAGAGTGCT
CAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTCGAACTCCTAGCTCA
TTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAGGGAAGTCGCCCCGA
CTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCATTTTCATCACAGCGT
TCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGGATGATCCTGGAGAA
GCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTGTGGAAGAGTATGAA
AACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAAAAACAGCCAGTATG
CTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCATTAGAAGAGGAAAGT
GTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTCGACAAAGTCAGCTG
GTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAATCAGTATATTGGGAA
AATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGGACCCTGATGCTCCC
ATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAATCCGTGCTGGAATG
ACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAAT
GTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAG
CTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACA
GTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTC
CCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAAT
CAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGC
AGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTT
TCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAA
GACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCA
GATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCA
GCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCA
CTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGAT
TCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTG
TGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCT
CAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCC
CTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAA
GACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACT
GGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGG


* Fusion transcript sequences (Full-length transcript).
>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_3380nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT
TTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATT
ATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTAC
AAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTA
AAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAA
AATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTC

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2794nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATC
GTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAAT
TCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGG
AACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAA
CCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATG
AACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATA
ACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTAC
TGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAG
ATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTC
TAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAAT
GAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAG
AATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGT

>In-frame_MDM2_ENST00000462284_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2906nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2855nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATG
CATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAA
CAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTG
AGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTA
TGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATC
AGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAG
CCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAG
TGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGA
AAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAA
TGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTAC
AGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAG
AGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTC
ATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGT
ACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAA
ATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAG
CATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGT
ATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATT

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2269nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATG
CAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCT
ATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATT
TGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTG
AGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGA
AGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACAC
ATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAAT
GCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGC
TCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTA
ATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAA
TTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAA

>In-frame_MDM2_ENST00000356290_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2381nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAAT
TTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCT
GTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAG
AACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAG
CAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGA
TGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAA
ACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTC
AAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACC
TGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACAT
ACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATG
CATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAA
CAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTG
AGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTA
TGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATC
AGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAG
CCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAG
TGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGA
AAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAA
TGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTAC
AGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAG
AGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTC

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2780nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA
ATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAG
ACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAAC
TATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTT
TTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTT
ATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGT

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2194nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCAC
TGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATT
CTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGT
GCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTC
AACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCC
TAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAG
ACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTG
GTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGA
AGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATC
TTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAA
ATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAA

>In-frame_MDM2_ENST00000540827_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2306nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_3200nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT
TTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATT
ATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTAC
AAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTA
AAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAA
AATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTC

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2614nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATC
GTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAAT
TCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGG
AACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAA
CCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATG
AACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATA
ACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTAC
TGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAG
ATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTC
TAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAAT
GAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAG
AATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGT

>In-frame_MDM2_ENST00000258149_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2726nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATC
TTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTC
TCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTC
AAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGA
ATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTT
TAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGG
TAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAA
AGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCC
TGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGA
CTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAA
TAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAA
GTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTG
AGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAA
AAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGG
CATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAG
GAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTA
ATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACA
AAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCT
TGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAA
AGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGG
TATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGC
TCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTT

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2780nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA
ATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAG
ACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAAC
TATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTT
TTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTT
ATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGT

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2194nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCAC
TGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATT
CTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGT
GCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTC
AACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCC
TAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAG
ACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTG
GTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGA
AGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATC
TTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAA
ATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAA

>In-frame_MDM2_ENST00000428863_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2306nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATC
AGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATG
AGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATG
GAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTA
ATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGG
CCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAG
AATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAAC
ATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACA
ATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTG
AAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAG
CTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGG
ATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAG
ATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAAC
AAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAG
CAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCA
GAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAA
CTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTG
CTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATG
AAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGT
ATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGC
TGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTA

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2927nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAA
GAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTG
TTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGA
ATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAA
TTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCAT
CAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAA
TGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATG
AGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAG
AAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGT
TGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGC
TTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTAT
CCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCC
TAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTT
AATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATC
GTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAA
TTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAA
TCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAAT
TAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2341nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTT
TAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCT
TGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAAC
AAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCT
TTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAAC
ACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACG
TCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGA
GAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATA
TGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAA
TGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAA
GTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAAT
ATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTT

>In-frame_MDM2_ENST00000258148_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2453nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTG
ATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCG
ACTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAG
CATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATC
CATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAA
GTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAG
AACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGG
TTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGG
GAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTC
ACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAA
GAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTG
TTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGA
ATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAA
TTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCAT
CAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAA
TGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATG
AGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAG
AAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGT
TGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGC
TTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTAT
CCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCC
TAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2985nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA
ATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTC
TTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGT
TTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGA
AAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTT
AAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAA
CATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAAAATAAGAGCATATA

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_2399nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTT
GACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAA
GTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGAT
GATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTT
CCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGT
ATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTG
GATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTG
CTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTG
GTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGG
TATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAAT
TTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATAT

>In-frame_MDM2_ENST00000350057_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2511nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGG
TTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGGA
CAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAA
CTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGG
AGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGT
GACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTG
GATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAG
AGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGC
AAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTA
CAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTAT
ACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTG
GAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGT
CATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCA
GCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTT
GTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAAT
GCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAA
AAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGG
AAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTT
AGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCAT
ACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTT
TCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2475nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA
GACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAA
TAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGT
GACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATT
CCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATC
ATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTA
AGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTA

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1889nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTA
AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG
GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA
GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT
AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC
AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC
TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA
AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG
GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG
CTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGT
TTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATAT

>In-frame_MDM2_ENST00000360430_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2001nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGAT
GCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGAC
TCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCA
TGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCA
TATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGT
GGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAA
CAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTT
TTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGA
GACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCAC
CTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGA
GAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTT
ACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAAT
ATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATT
GATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCA
AAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATG
GAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAG
TGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAA
AAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTG
TTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTT
TGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCC
TCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTA
GACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2550nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT
ATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATG
TAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTT
TTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAA
AGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAA
CAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCA

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1964nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA
CTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATA
CTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTC

>In-frame_MDM2_ENST00000299252_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_2076nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA
AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000229179_chr12_69113121_+_2460nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT
ATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATG
TAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTT
TTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAA
AGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAA
CAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCA

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000378905_chr12_69113121_+_1874nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGGAGGATCGTTTAAAAATTGATGTAATT
GACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCAC
GAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCA
CTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAG
CATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATAT
GAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGAT
GGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCA
ATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGC
CACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGA
CTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATA
CTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTC

>In-frame_MDM2_ENST00000348801_chr12_69229764_+_NUP107_ENST00000539906_chr12_69113121_+_1986nt
ATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGATCTTGATGCTGGTGTAAGTGAA
CATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGC
CTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACA
CTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGG
AAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAG
CTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACA
TCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAA
GCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTG
ATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTC
CGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAAT
CTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAG
CGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGAT
AATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGG
TTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCT
GCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCT
GCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATG
AATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATG
GATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGG
TGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTG
TGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAA
CTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGAC
CCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTT

>In-frame_MDM2_ENST00000462284_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_3629nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAG
AGGTGACACGGACTGCACGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAA
GAAACCAGGTTATCCCTCGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCT
GCATTCTTGGAACAGGAGGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACA
GTAACTGGGCAGCTGCATTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTG
CTGTTATGTTACGTGAGGATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGA
GTACAGTTTTTGATCTTGTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTG
GACTTCAAAAATTTTCAAAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAG
ACAGAATACAGTCTGCATTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTC
AGAGGGATTCACTTGTTCGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATA
TTGAGTTTTATGCAAAATCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTC
CGCTTGTCACTGAATTGGACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCA
AATATCTCTTTACTCTAATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACAC
TTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGA
AAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGC
TGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACAT
CAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAG
CTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGA
TGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCC
GTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATC
TTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGC
GCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATA
ATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGT
TGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTG
CAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTG
CTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGA
ATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGG
ATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGT
GGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGT
GTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAAC
TGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACC
CATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTA
TTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGT
AGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTT
TTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAA
GTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAAC
AAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAA

>In-frame_MDM2_ENST00000258148_chr12_69202271_+_NUP107_ENST00000229179_chr12_69082742_+_3341nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCAC
GGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTC
GAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAG
GGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCAT
TTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGG
ATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTG
TGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAA
AAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCAT
TAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTC
GACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAAT
CAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGG
ACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAA
TCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGT
ACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAA
TGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACA
CCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATG
AAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAG
TTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAAT
GGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGA
CCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCT
GTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGT
TGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATC
ATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGC
AGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGA
AAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTA
TCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAAC
CTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAG
GGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAG
AGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGA
TATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTA
AGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTC
AGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTT
GCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCT
CTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAAT
TAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGC
CAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATA
ACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAAAATAAGAGCATATAAAGA


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FusionGenePPI for MDM2_NUP107


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check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MDM2TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2NUP107SEH1L, NUP133, NUP85, NUP160, NUP43, NUP37, SEC13, TPR, NUP214, KPNB1, SIRT7, NUP98, WRNIP1, CUL3, CENPF, NUP153, TP53BP1, PNPT1, EIF4B, CORO1B, MYL1, C1QBP, CPSF6, VCP, PYCARD, CUL7, OBSL1, SUZ12, EED, PNKD, NTRK1, IFI16, SYNE1, APC, PRKDC, RRP1B, NALCN, CD1E, ACTBL2, HSP90AB1, XPO1, SENP1, SENP2, AHCTF1, RANGAP1, H2AFV, NUP50, RANBP2, B9D2, ACLY, RCC1, GLE1, ITPR2, KPNA4, NUP88, RAN, UBE2I, SUMO1, AAAS, RAE1, NUP155, NUP93, NUPL1, WDR1, NXF1, IPO7, NUPL2, NUP205, NUP210, NUP188, NUP62, NXT1, SEC61A1, NUP54, TMEM214, SMPD4, NDC1, KRAS, IP6K3, TMEM209, NUP35, RPUSD3, RGPD8, POM121C, FOXA3, FOXI2, FOXK2, FOXL1, FOXP3, FOXQ1, CDC5L, ZNF746, DUSP13, SPAST, UXS1, SIGLECL1, CD70, RAF1, PDHA1, TRIM25, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911150_230280498PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911150_230280498PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911223_232280498USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911223_232280498USP7


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19170_306-2437MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15170_3060322MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13170_3060266MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16170_306-2322MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14170_3060297MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13170_306-2219MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12170_3060219MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14170_306-2271MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111170_3064498MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15170_306-2297MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79170_306219437MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35170_306104322MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23170_30674266MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46170_306104322MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24170_30679297MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13170_306-92219MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12170_3060219MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34170_30679271MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000462284+911170_306280498MTBP
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35170_30679297MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79170_306219437MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35170_306104322MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23170_30674266MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46170_306104322MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24170_30679297MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13170_306-92219MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12170_3060219MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34170_30679271MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000462284+911170_306280498MTBP
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35170_30679297MTBP
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19150_230-2437PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15150_2300322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13150_2300266PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16150_230-2322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14150_2300297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13150_230-2219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12150_2300219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14150_230-2271PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111150_2304498PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15150_230-2297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79150_230219437PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35150_230104322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23150_23074266PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46150_230104322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24150_23079297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13150_230-92219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12150_2300219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34150_23079271PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35150_23079297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79150_230219437PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35150_230104322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23150_23074266PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46150_230104322PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24150_23079297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13150_230-92219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12150_2300219PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34150_23079271PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35150_23079297PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69202271chr12:69082742ENST00000258149+19223_232-2437USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000299252+15223_2320322USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000348801+13223_2320266USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000356290+16223_232-2322USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000360430+14223_2320297USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000393412+13223_232-2219USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000393413+12223_2320219USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000428863+14223_232-2271USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000462284+111223_2324498USP7
HgeneMDM2chr12:69202271chr12:69082742ENST00000540827+15223_232-2297USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000258149+79223_232219437USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000299252+35223_232104322USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000348801+23223_23274266USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000356290+46223_232104322USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000360430+24223_23279297USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000393412+13223_232-92219USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000393413+12223_2320219USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000428863+34223_23279271USP7
HgeneMDM2chr12:69229764chr12:69113121ENST00000540827+35223_23279297USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000258149+79223_232219437USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000299252+35223_232104322USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000348801+23223_23274266USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000356290+46223_232104322USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000360430+24223_23279297USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000393412+13223_232-92219USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000393413+12223_2320219USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000428863+34223_23279271USP7
HgeneMDM2chr12:69229764chr12:69135593ENST00000540827+35223_23279297USP7


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MDM2_NUP107


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneMDM2Q00987DB01593ZincE3 ubiquitin-protein ligase Mdm2small moleculeapproved|investigational

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RelatedDiseases for MDM2_NUP107


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMDM2C0007131Non-Small Cell Lung Carcinoma2CTD_human
HgeneMDM2C0007621Neoplastic Cell Transformation1CTD_human
HgeneMDM2C0019693HIV Infections1CTD_human
HgeneMDM2C0021364Male infertility1CTD_human
HgeneMDM2C0025202melanoma1CTD_human
HgeneMDM2C0032927Precancerous Conditions1CTD_human
HgeneMDM2C0033578Prostatic Neoplasms1CTD_human
HgeneMDM2C1458155Mammary Neoplasms1CTD_human
TgeneNUP107C4225228NEPHROTIC SYNDROME, TYPE 111UNIPROT