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Fusion gene ID: 21376 |
FusionGeneSummary for MDM2_BRI3BP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MDM2_BRI3BP | Fusion gene ID: 21376 | Hgene | Tgene | Gene symbol | MDM2 | BRI3BP | Gene ID | 4193 | 140707 |
| Gene name | MDM2 proto-oncogene | BRI3 binding protein | |
| Synonyms | ACTFS|HDMX|hdm2 | BNAS1|HCCR-1|HCCR-2|HCCRBP-1|HCCRBP-3|KG19 | |
| Cytomap | 12q15 | 12q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, hum | BRI3-binding proteinI3-binding proteincervical cancer 1 proto-oncogene-binding protein KG19cervical cancer oncogene binding protein | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | Q00987 | Q8WY22 | |
| Ensembl transtripts involved in fusion gene | ENST00000462284, ENST00000356290, ENST00000540827, ENST00000258149, ENST00000428863, ENST00000393412, ENST00000258148, ENST00000544561, ENST00000393410, ENST00000393413, ENST00000517852, ENST00000545204, ENST00000350057, ENST00000360430, ENST00000299252, ENST00000348801, ENST00000478070, ENST00000544125, | ENST00000341446, | |
| Fusion gene scores | * DoF score | 24 X 14 X 8=2688 | 3 X 3 X 3=27 |
| # samples | 25 | 3 | |
| ** MAII score | log2(25/2688*10)=-3.42653313811667 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: MDM2 [Title/Abstract] AND BRI3BP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MDM2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 9271120|17310983 |
| Hgene | MDM2 | GO:0006511 | ubiquitin-dependent protein catabolic process | 11278372|15314173|16173922|17310983 |
| Hgene | MDM2 | GO:0016567 | protein ubiquitination | 9450543|15878855|19656744|20153724 |
| Hgene | MDM2 | GO:0031648 | protein destabilization | 9529249|10360174|15314173 |
| Hgene | MDM2 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 11278372 |
| Hgene | MDM2 | GO:0034504 | protein localization to nucleus | 10360174 |
| Hgene | MDM2 | GO:0042176 | regulation of protein catabolic process | 9153395 |
| Hgene | MDM2 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator | 9529249|10360174 |
| Hgene | MDM2 | GO:0045184 | establishment of protein localization | 10360174 |
| Hgene | MDM2 | GO:0045892 | negative regulation of transcription, DNA-templated | 9271120 |
| Hgene | MDM2 | GO:0065003 | protein-containing complex assembly | 10608892|12915590 |
| Hgene | MDM2 | GO:0071157 | negative regulation of cell cycle arrest | 9529249 |
| Hgene | MDM2 | GO:0071480 | cellular response to gamma radiation | 16213212 |
| Hgene | MDM2 | GO:0072717 | cellular response to actinomycin D | 15314173 |
| Hgene | MDM2 | GO:1901797 | negative regulation of signal transduction by p53 class mediator | 16173922 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-KK-A7B2-01A | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000462284 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000356290 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000540827 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| In-frame | ENST00000258149 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000428863 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000393412 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| In-frame | ENST00000258148 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000544561 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000393410 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000393413 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000517852 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000545204 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| In-frame | ENST00000350057 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000360430 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000299252 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000348801 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| Frame-shift | ENST00000478070 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
| intron-3CDS | ENST00000544125 | ENST00000341446 | MDM2 | chr12 | 69214154 | + | BRI3BP | chr12 | 125509890 | + |
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FusionProtFeatures for MDM2_BRI3BP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MDM2 | BRI3BP |
| Involved in tumorigenesis and may function bystabilizing p53/TP53. {ECO:0000269|PubMed:17943721}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 27_107 | 113 | 437 | Domain | Note=SWIB |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 27_107 | 119 | 498 | Domain | Note=SWIB |
| Tgene | >BRI3BP | chr12:69214154 | chr12:125509890 | ENST00000341446 | + | 0 | 3 | 217_247 | -31 | 252 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >BRI3BP | chr12:69214154 | chr12:125509890 | ENST00000341446 | + | 0 | 3 | 125_145 | -31 | 252 | Transmembrane | Helical |
| Tgene | >BRI3BP | chr12:69214154 | chr12:125509890 | ENST00000341446 | + | 0 | 3 | 13_33 | -31 | 252 | Transmembrane | Helical |
| Tgene | >BRI3BP | chr12:69214154 | chr12:125509890 | ENST00000341446 | + | 0 | 3 | 146_166 | -31 | 252 | Transmembrane | Helical |
| Tgene | >BRI3BP | chr12:69214154 | chr12:125509890 | ENST00000341446 | + | 0 | 3 | 185_205 | -31 | 252 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 210_215 | 113 | 437 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 243_301 | 113 | 437 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 210_215 | 0 | 322 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 243_301 | 0 | 322 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 210_215 | 0 | 266 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 243_301 | 0 | 266 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 210_215 | -102 | 322 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 243_301 | -102 | 322 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 210_215 | 0 | 297 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 243_301 | 0 | 297 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 210_215 | -92 | 219 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 243_301 | -92 | 219 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 210_215 | 0 | 219 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 243_301 | 0 | 219 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 210_215 | -102 | 271 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 243_301 | -102 | 271 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 210_215 | 119 | 498 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 243_301 | 119 | 498 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 210_215 | -102 | 297 | Compositional bias | Note=Poly-Ser |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 243_301 | -102 | 297 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 27_107 | 0 | 322 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 27_107 | 0 | 266 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 27_107 | -102 | 322 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 27_107 | 0 | 297 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 27_107 | -92 | 219 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 27_107 | 0 | 219 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 27_107 | -102 | 271 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 27_107 | -102 | 297 | Domain | Note=SWIB |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 179_185 | 113 | 437 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 190_202 | 113 | 437 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 466_473 | 113 | 437 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 179_185 | 0 | 322 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 190_202 | 0 | 322 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 466_473 | 0 | 322 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 179_185 | 0 | 266 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 190_202 | 0 | 266 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 466_473 | 0 | 266 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 179_185 | -102 | 322 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 190_202 | -102 | 322 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 466_473 | -102 | 322 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 179_185 | 0 | 297 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 190_202 | 0 | 297 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 466_473 | 0 | 297 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 179_185 | -92 | 219 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 190_202 | -92 | 219 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 466_473 | -92 | 219 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 179_185 | 0 | 219 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 190_202 | 0 | 219 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 466_473 | 0 | 219 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 179_185 | -102 | 271 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 190_202 | -102 | 271 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 466_473 | -102 | 271 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 179_185 | 119 | 498 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 190_202 | 119 | 498 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 466_473 | 119 | 498 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 179_185 | -102 | 297 | Motif | Nuclear localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 190_202 | -102 | 297 | Motif | Note=Nuclear export signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 466_473 | -102 | 297 | Motif | Nucleolar localization signal |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 210_304 | 113 | 437 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 242_331 | 113 | 437 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 210_304 | 0 | 322 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 242_331 | 0 | 322 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 210_304 | 0 | 266 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 242_331 | 0 | 266 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 210_304 | -102 | 322 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 242_331 | -102 | 322 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 210_304 | 0 | 297 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 242_331 | 0 | 297 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 210_304 | -92 | 219 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 242_331 | -92 | 219 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 210_304 | 0 | 219 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 242_331 | 0 | 219 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 210_304 | -102 | 271 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 242_331 | -102 | 271 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 210_304 | 119 | 498 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 242_331 | 119 | 498 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 210_304 | -102 | 297 | Region | Note=ARF-binding |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 242_331 | -102 | 297 | Region | Note=Region II |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 299_328 | 113 | 437 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 438_479 | 113 | 437 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 299_328 | 0 | 322 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 438_479 | 0 | 322 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 299_328 | 0 | 266 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 438_479 | 0 | 266 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 299_328 | -102 | 322 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 438_479 | -102 | 322 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 299_328 | 0 | 297 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 438_479 | 0 | 297 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 299_328 | -92 | 219 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 438_479 | -92 | 219 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 299_328 | 0 | 219 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 438_479 | 0 | 219 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 299_328 | -102 | 271 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 438_479 | -102 | 271 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 299_328 | 119 | 498 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 438_479 | 119 | 498 | Zinc finger | RING-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 299_328 | -102 | 297 | Zinc finger | RanBP2-type |
| Hgene | >MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 438_479 | -102 | 297 | Zinc finger | RING-type |
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FusionGeneSequence for MDM2_BRI3BP |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MDM2_ENST00000462284_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_2053aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEVSRPGGSTVTSTLSQKTKTEEKNPKPQTILINTTEQESGAVXGYFHPPGSSXDTFPEERK DHXRGTTHEVXLVGEKIFFKQRIXPYLVVQXEKFICAXSIKLIFSSIXIHLLXGFLIKADXVKFIKTLHGGEEYANLTFEKSLNASVCFH SLGIGGXGLCALFSCSQTVSFISCYFWWMLTXFMNVVTSKCGQLGCRMQLNLFWILETPAKPPSVLFLNEDIAISRRPEIFFPLCFDVFX PQHFETENARRGQEMSWGFDARKYLVRIGDCSRIYCMSQFAVCSLGLYTKAIPLRVFFFFFXFPQDLRGKTNSSSXYSQVYCCLERSSGT ISSNKQAFEKIXILFPEIFTIHRCFLSEICCVLLLGSLCGQRVGLARWTAVGILGKGVSEGVAQGLVETPFCXDLFFKKESPRPGAVADA CNPSALGGRGVWITXGQEFKTSLANMVKPPSLLKIQKLVRHGGGCLXSSYSGGXGRRIAXTWEVEVAVSRDHATALQPRQQSKTSSXKKK KKPSILQLXSCWGSRLSLWPLPGHRCTLATRSQCPACRFIDNPCQTCYNQDLMVQVSVWRRFSCLPLLVXCSCEVLFLVASIWKTDADVF VDVVETFETSVSKVHMMGPKLSWRVPFTSXNVHLFQVHVYSVCMDIXDLLEQAGQGGSPLXSQHFGRPRQVDHLRSGVXDQPGQQSETPS LLKIQKLARPGGGRLXSQLLGRLRLENRLNMGGGGCSQLRSYHHTLASATEXDSVSKKIICWIESFFFXDGVSLSTRLECSGTISAHCKL RLLGSRHSPTSASQVAGTTGAHHHARLIFYIFSRDGVSPCXPGWSRSPDLVIRPPRPPKVLGLQAXATALGLDQIFIHAHWNTGLLGXNH SSFVIXILVDESILAQGINNSGGHLYLLSFCAFGYTTFRYXNSFAYVGQGKTWHSVRKANDRQPCLGPSLVYGHCKMPACXGLSCHWAGC NTRFIPPPTLLPETXRALCSIEISIRSSFXLVFNXGRXHDIWVLVDXDLKHQFKIAVENMHYFFFPLWLSVGSEASFIAXYILVKDVFIF NERTYSXXVSPQGRNSDRNSDYLKLXXKSXMLDLKKTWVLLHRFHLFWGTSYPKIIGDFFVPSPFHGTLXGVGIGPPLATRHMSLFFSLF CMWKNVFLYHISYLERNLFSIFRAVEYISVTLHXMXRKSILMKTGSVIIKTQCLKYLNQCXFPSVSVSQXILVLLRTENNPEKEKDQPSL DCWNCMDVLGLVXXSLPXHPSKDAFVECKPFINILSRLGAVAQACNPSTLGGQGGWITCGREFETSLANIVKSRLYQKIQKKKKKKKXPG VVVGSCSPSYSGGXGGRIVXTWEAEVAVNXDHTTVLQLRRQSETQSQKKKKVCVCVYICIYIYTHTHFPIPVGITRPLVSFALDFSPHII SGNRAQQXNFWEADLVNRACVLIHKGXVNAVERCFIHLPQKXEPVSCRSREAAMSGNWDYVFMTVMVVTKWGGPLWGAEXERKGLGQXLG RLXYDFVHAREGCLVERMXAAXSLIWPCDSGLWSVKNNSCQMAXTWLMQFVASGNPELLPFCDHCYFLRCFXXMSSALQVDTXXLLPDGF PNWLTXPKSQLLPSILHXKEFLRLLRGQLPHSXLFYFXWSIPSATFLFMAIXIVGLXLLTCEXXEYILQNLTXYPXNSYWTTISVMYSIW CKQILFSILNYSVFCFSLICRRCTSTSFSLVVAXNADCHLHCLLKSCGSEWYYXPCVLMSFCRFKGFIVVSIXYLHVCLISEYHVIKLIN LXWXWXLAHTKNPMKQLSPSSXLEITLVRYGIHYQQWIHDXLHILCIWLXILYSIXFGTXYKSIXFEXCVCVHGVCVCVHFSFVSLGKLI >In-frame_MDM2_ENST00000258149_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_2047aa MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPS FSVKEHRKIYTMIYRNLVVVNQQEVSRPGGSTVTSTLSQKTKTEEKNPKPQTILINTTEQESGAVXGYFHPPGSSXDTFPEERKDHXRGT THEVXLVGEKIFFKQRIXPYLVVQXEKFICAXSIKLIFSSIXIHLLXGFLIKADXVKFIKTLHGGEEYANLTFEKSLNASVCFHSLGIGG XGLCALFSCSQTVSFISCYFWWMLTXFMNVVTSKCGQLGCRMQLNLFWILETPAKPPSVLFLNEDIAISRRPEIFFPLCFDVFXPQHFET ENARRGQEMSWGFDARKYLVRIGDCSRIYCMSQFAVCSLGLYTKAIPLRVFFFFFXFPQDLRGKTNSSSXYSQVYCCLERSSGTISSNKQ AFEKIXILFPEIFTIHRCFLSEICCVLLLGSLCGQRVGLARWTAVGILGKGVSEGVAQGLVETPFCXDLFFKKESPRPGAVADACNPSAL GGRGVWITXGQEFKTSLANMVKPPSLLKIQKLVRHGGGCLXSSYSGGXGRRIAXTWEVEVAVSRDHATALQPRQQSKTSSXKKKKKPSIL QLXSCWGSRLSLWPLPGHRCTLATRSQCPACRFIDNPCQTCYNQDLMVQVSVWRRFSCLPLLVXCSCEVLFLVASIWKTDADVFVDVVET FETSVSKVHMMGPKLSWRVPFTSXNVHLFQVHVYSVCMDIXDLLEQAGQGGSPLXSQHFGRPRQVDHLRSGVXDQPGQQSETPSLLKIQK LARPGGGRLXSQLLGRLRLENRLNMGGGGCSQLRSYHHTLASATEXDSVSKKIICWIESFFFXDGVSLSTRLECSGTISAHCKLRLLGSR HSPTSASQVAGTTGAHHHARLIFYIFSRDGVSPCXPGWSRSPDLVIRPPRPPKVLGLQAXATALGLDQIFIHAHWNTGLLGXNHSSFVIX ILVDESILAQGINNSGGHLYLLSFCAFGYTTFRYXNSFAYVGQGKTWHSVRKANDRQPCLGPSLVYGHCKMPACXGLSCHWAGCNTRFIP PPTLLPETXRALCSIEISIRSSFXLVFNXGRXHDIWVLVDXDLKHQFKIAVENMHYFFFPLWLSVGSEASFIAXYILVKDVFIFNERTYS XXVSPQGRNSDRNSDYLKLXXKSXMLDLKKTWVLLHRFHLFWGTSYPKIIGDFFVPSPFHGTLXGVGIGPPLATRHMSLFFSLFCMWKNV FLYHISYLERNLFSIFRAVEYISVTLHXMXRKSILMKTGSVIIKTQCLKYLNQCXFPSVSVSQXILVLLRTENNPEKEKDQPSLDCWNCM DVLGLVXXSLPXHPSKDAFVECKPFINILSRLGAVAQACNPSTLGGQGGWITCGREFETSLANIVKSRLYQKIQKKKKKKKXPGVVVGSC SPSYSGGXGGRIVXTWEAEVAVNXDHTTVLQLRRQSETQSQKKKKVCVCVYICIYIYTHTHFPIPVGITRPLVSFALDFSPHIISGNRAQ QXNFWEADLVNRACVLIHKGXVNAVERCFIHLPQKXEPVSCRSREAAMSGNWDYVFMTVMVVTKWGGPLWGAEXERKGLGQXLGRLXYDF VHAREGCLVERMXAAXSLIWPCDSGLWSVKNNSCQMAXTWLMQFVASGNPELLPFCDHCYFLRCFXXMSSALQVDTXXLLPDGFPNWLTX PKSQLLPSILHXKEFLRLLRGQLPHSXLFYFXWSIPSATFLFMAIXIVGLXLLTCEXXEYILQNLTXYPXNSYWTTISVMYSIWCKQILF SILNYSVFCFSLICRRCTSTSFSLVVAXNADCHLHCLLKSCGSEWYYXPCVLMSFCRFKGFIVVSIXYLHVCLISEYHVIKLINLXWXWX LAHTKNPMKQLSPSSXLEITLVRYGIHYQQWIHDXLHILCIWLXILYSIXFGTXYKSIXFEXCVCVHGVCVCVHFSFVSLGKLILQISYI >In-frame_MDM2_ENST00000258148_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_2053aa MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEVSRPGGSTVTSTLSQKTKTEEKNPKPQTILINTTEQESGAVXGYFHPPGSSXDTFPEERK DHXRGTTHEVXLVGEKIFFKQRIXPYLVVQXEKFICAXSIKLIFSSIXIHLLXGFLIKADXVKFIKTLHGGEEYANLTFEKSLNASVCFH SLGIGGXGLCALFSCSQTVSFISCYFWWMLTXFMNVVTSKCGQLGCRMQLNLFWILETPAKPPSVLFLNEDIAISRRPEIFFPLCFDVFX PQHFETENARRGQEMSWGFDARKYLVRIGDCSRIYCMSQFAVCSLGLYTKAIPLRVFFFFFXFPQDLRGKTNSSSXYSQVYCCLERSSGT ISSNKQAFEKIXILFPEIFTIHRCFLSEICCVLLLGSLCGQRVGLARWTAVGILGKGVSEGVAQGLVETPFCXDLFFKKESPRPGAVADA CNPSALGGRGVWITXGQEFKTSLANMVKPPSLLKIQKLVRHGGGCLXSSYSGGXGRRIAXTWEVEVAVSRDHATALQPRQQSKTSSXKKK KKPSILQLXSCWGSRLSLWPLPGHRCTLATRSQCPACRFIDNPCQTCYNQDLMVQVSVWRRFSCLPLLVXCSCEVLFLVASIWKTDADVF VDVVETFETSVSKVHMMGPKLSWRVPFTSXNVHLFQVHVYSVCMDIXDLLEQAGQGGSPLXSQHFGRPRQVDHLRSGVXDQPGQQSETPS LLKIQKLARPGGGRLXSQLLGRLRLENRLNMGGGGCSQLRSYHHTLASATEXDSVSKKIICWIESFFFXDGVSLSTRLECSGTISAHCKL RLLGSRHSPTSASQVAGTTGAHHHARLIFYIFSRDGVSPCXPGWSRSPDLVIRPPRPPKVLGLQAXATALGLDQIFIHAHWNTGLLGXNH SSFVIXILVDESILAQGINNSGGHLYLLSFCAFGYTTFRYXNSFAYVGQGKTWHSVRKANDRQPCLGPSLVYGHCKMPACXGLSCHWAGC NTRFIPPPTLLPETXRALCSIEISIRSSFXLVFNXGRXHDIWVLVDXDLKHQFKIAVENMHYFFFPLWLSVGSEASFIAXYILVKDVFIF NERTYSXXVSPQGRNSDRNSDYLKLXXKSXMLDLKKTWVLLHRFHLFWGTSYPKIIGDFFVPSPFHGTLXGVGIGPPLATRHMSLFFSLF CMWKNVFLYHISYLERNLFSIFRAVEYISVTLHXMXRKSILMKTGSVIIKTQCLKYLNQCXFPSVSVSQXILVLLRTENNPEKEKDQPSL DCWNCMDVLGLVXXSLPXHPSKDAFVECKPFINILSRLGAVAQACNPSTLGGQGGWITCGREFETSLANIVKSRLYQKIQKKKKKKKXPG VVVGSCSPSYSGGXGGRIVXTWEAEVAVNXDHTTVLQLRRQSETQSQKKKKVCVCVYICIYIYTHTHFPIPVGITRPLVSFALDFSPHII SGNRAQQXNFWEADLVNRACVLIHKGXVNAVERCFIHLPQKXEPVSCRSREAAMSGNWDYVFMTVMVVTKWGGPLWGAEXERKGLGQXLG RLXYDFVHAREGCLVERMXAAXSLIWPCDSGLWSVKNNSCQMAXTWLMQFVASGNPELLPFCDHCYFLRCFXXMSSALQVDTXXLLPDGF PNWLTXPKSQLLPSILHXKEFLRLLRGQLPHSXLFYFXWSIPSATFLFMAIXIVGLXLLTCEXXEYILQNLTXYPXNSYWTTISVMYSIW CKQILFSILNYSVFCFSLICRRCTSTSFSLVVAXNADCHLHCLLKSCGSEWYYXPCVLMSFCRFKGFIVVSIXYLHVCLISEYHVIKLIN LXWXWXLAHTKNPMKQLSPSSXLEITLVRYGIHYQQWIHDXLHILCIWLXILYSIXFGTXYKSIXFEXCVCVHGVCVCVHFSFVSLGKLI >In-frame_MDM2_ENST00000350057_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_2022aa MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEV SRPGGSTVTSTLSQKTKTEEKNPKPQTILINTTEQESGAVXGYFHPPGSSXDTFPEERKDHXRGTTHEVXLVGEKIFFKQRIXPYLVVQX EKFICAXSIKLIFSSIXIHLLXGFLIKADXVKFIKTLHGGEEYANLTFEKSLNASVCFHSLGIGGXGLCALFSCSQTVSFISCYFWWMLT XFMNVVTSKCGQLGCRMQLNLFWILETPAKPPSVLFLNEDIAISRRPEIFFPLCFDVFXPQHFETENARRGQEMSWGFDARKYLVRIGDC SRIYCMSQFAVCSLGLYTKAIPLRVFFFFFXFPQDLRGKTNSSSXYSQVYCCLERSSGTISSNKQAFEKIXILFPEIFTIHRCFLSEICC VLLLGSLCGQRVGLARWTAVGILGKGVSEGVAQGLVETPFCXDLFFKKESPRPGAVADACNPSALGGRGVWITXGQEFKTSLANMVKPPS LLKIQKLVRHGGGCLXSSYSGGXGRRIAXTWEVEVAVSRDHATALQPRQQSKTSSXKKKKKPSILQLXSCWGSRLSLWPLPGHRCTLATR SQCPACRFIDNPCQTCYNQDLMVQVSVWRRFSCLPLLVXCSCEVLFLVASIWKTDADVFVDVVETFETSVSKVHMMGPKLSWRVPFTSXN VHLFQVHVYSVCMDIXDLLEQAGQGGSPLXSQHFGRPRQVDHLRSGVXDQPGQQSETPSLLKIQKLARPGGGRLXSQLLGRLRLENRLNM GGGGCSQLRSYHHTLASATEXDSVSKKIICWIESFFFXDGVSLSTRLECSGTISAHCKLRLLGSRHSPTSASQVAGTTGAHHHARLIFYI FSRDGVSPCXPGWSRSPDLVIRPPRPPKVLGLQAXATALGLDQIFIHAHWNTGLLGXNHSSFVIXILVDESILAQGINNSGGHLYLLSFC AFGYTTFRYXNSFAYVGQGKTWHSVRKANDRQPCLGPSLVYGHCKMPACXGLSCHWAGCNTRFIPPPTLLPETXRALCSIEISIRSSFXL VFNXGRXHDIWVLVDXDLKHQFKIAVENMHYFFFPLWLSVGSEASFIAXYILVKDVFIFNERTYSXXVSPQGRNSDRNSDYLKLXXKSXM LDLKKTWVLLHRFHLFWGTSYPKIIGDFFVPSPFHGTLXGVGIGPPLATRHMSLFFSLFCMWKNVFLYHISYLERNLFSIFRAVEYISVT LHXMXRKSILMKTGSVIIKTQCLKYLNQCXFPSVSVSQXILVLLRTENNPEKEKDQPSLDCWNCMDVLGLVXXSLPXHPSKDAFVECKPF INILSRLGAVAQACNPSTLGGQGGWITCGREFETSLANIVKSRLYQKIQKKKKKKKXPGVVVGSCSPSYSGGXGGRIVXTWEAEVAVNXD HTTVLQLRRQSETQSQKKKKVCVCVYICIYIYTHTHFPIPVGITRPLVSFALDFSPHIISGNRAQQXNFWEADLVNRACVLIHKGXVNAV ERCFIHLPQKXEPVSCRSREAAMSGNWDYVFMTVMVVTKWGGPLWGAEXERKGLGQXLGRLXYDFVHAREGCLVERMXAAXSLIWPCDSG LWSVKNNSCQMAXTWLMQFVASGNPELLPFCDHCYFLRCFXXMSSALQVDTXXLLPDGFPNWLTXPKSQLLPSILHXKEFLRLLRGQLPH SXLFYFXWSIPSATFLFMAIXIVGLXLLTCEXXEYILQNLTXYPXNSYWTTISVMYSIWCKQILFSILNYSVFCFSLICRRCTSTSFSLV VAXNADCHLHCLLKSCGSEWYYXPCVLMSFCRFKGFIVVSIXYLHVCLISEYHVIKLINLXWXWXLAHTKNPMKQLSPSSXLEITLVRYG IHYQQWIHDXLHILCIWLXILYSIXFGTXYKSIXFEXCVCVHGVCVCVHFSFVSLGKLILQISYIEINVSGIFLQSDIYIPLIYXITGFG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MDM2_ENST00000462284_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6159nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAG GTCAGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCAAACAATCTTA ATAAACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGAAGAGCGGAAA GATCATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTTAGTTGTACAG TAAGAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAATAAAGGCAGAT TGAGTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGTTTGTTTTCAC AGCTTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTGGTGGATGTTG ACTTAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGAGACCCCTGCC AAGCCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGATGTATTTTAA CCTCAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAGGATTGGAGAT TGCTCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTTTTTTTTTTTC TTTTGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATCCTCAGGAACA ATTAGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATCTGAAATCTGT TGTGTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGGAGTTTCAGAA GGTGTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGTGGCTGATGCC TGTAATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCCG TCTCTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGA ACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAA AAAAAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTACCCTGGCAACC CGCTCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTCAGTTTGGAGA AGATTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGCAGATGTTTTT GTGGATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATTCACTTCCTGA AACGTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGGCTCACCCCTA TAATCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGAAACCCCGTCT CTACTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCGCTTGAAC ATGGGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAAAAAAATTATT TGCTGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGCTC CGCCTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCTAATTTTTTAT ATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTG CTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGGTTGAAATCAT TCTAGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCTTCTTTCCTTT TGTGCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCGCAAAGCTAAT GATCGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTGGGCTGGGTGT AATACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATCATCATTTTAA CTTGTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGTCGAAAATATG CACTATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGTCTTCATTTTT AATGAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATAGAAATCCTAG ATGCTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGGGGATTTTTTT GTTCCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTTTTCTCTCTTT TGTATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATATATTAGCGTA ACACTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCTTAATCAGTGT TAATTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCAGCCCTCTCTA GATTGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGAGTGCAAACCT TTCATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGCGGT CGGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAAATAGCCAGGT GTGGTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGCAGTGAACTGA GATCACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATATATATGTATA TATATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCCCCATATCATT TCTGGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTAAGTGAATGCC GTTGAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAACTGGGACTAT GTCTTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCAGTGATTAGGA AGACTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCCCTGTGATTCA GGCTTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGAATTGCTTCCT TTCTGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCCTGATGGGTTT CCGAACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGGTCAGCTGCCC CACTCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTGACTCCTCACT TGTGAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTATAGTATCTGG TGTAAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAGTTTTTCTCTT GTGGTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGTTCTCATGTCT TTTTGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAAACTGATTAAC TTGTGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACTTGTGAGGTAT GGTATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATTTGGCACTTAA TATAAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGGGAAACTGATT CTACAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAATCACTGGCTTT GGTGTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGTAATTTTGTTG >In-frame_MDM2_ENST00000258149_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6141nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCA AAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTAT ATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGC TTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAGGTCAGCCGGCCGGGCGGG TCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCAAACAATCTTAATAAACACGACTGAGCAA GAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGAAGAGCGGAAAGATCATTGACGTGGAACT ACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTTAGTTGTACAGTAAGAGAAATTTATCTGT GCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAATAAAGGCAGATTGAGTCAAGTTTATTAAA ACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGTTTGTTTTCACAGCTTAGGGATTGGTGGG TGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTGGTGGATGTTGACTTAGTTCATGAATGTT GTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGAGACCCCTGCCAAGCCCCCATCAGTCCTA TTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGATGTATTTTAACCTCAACATTTTGAAACG GAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAGGATTGGAGATTGCTCCAGAATCTACTGC ATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTTTTTTTTTTTCTTTTGATTTCCTCAGGAC CTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATCCTCAGGAACAATTAGCAGCAATAAGCAA GCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATCTGAAATCTGTTGTGTCCTCCTTTTAGGC AGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGGAGTTTCAGAAGGTGTGGCTCAGGGGCTG GTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGTGGCTGATGCCTGTAATCCCAGCGCTTTG GGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCCGTCTCTACTAAAAATACAA AAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTT GCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAAAAAAAGCCCAGCATTTTG CAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTACCCTGGCAACCCGCTCACAGTGCCCTGCG TGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTCAGTTTGGAGAAGATTTAGCTGTCTACCA CTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGCAGATGTTTTTGTGGATGTTGTTGAGACT TTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATTCACTTCCTGAAACGTGCACCTGTTTCAG GTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGGCTCACCCCTATAATCCCAACACTTTGGG AGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGAAACCCCGTCTCTACTAAAAATACAAAAA TTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCGCTTGAACATGGGAGGCGGAGGTTGC AGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAAAAAAATTATTTGCTGGATCGAATCTTTT TTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACGC CATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCTAATTTTTTATATTTTTAGTAGAGACGGG GTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGA GCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGGTTGAAATCATTCTAGTTTTGTCATTTAG ATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCTTCTTTCCTTTTGTGCATTTGGCTATACC ACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCGCAAAGCTAATGATCGCCAGCCCTGCCTT GGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTGGGCTGGGTGTAATACCCGCTTCATTCCT CCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATCATCATTTTAACTTGTATTCAACTGAGGG AGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGTCGAAAATATGCACTATTTTTTTTTTCCA CTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGTCTTCATTTTTAATGAAAGAACCTACAGT TAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATAGAAATCCTAGATGCTAGATTTGAAGAAA ACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGGGGATTTTTTTGTTCCTTCTCCATTCCAT GGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTTTTCTCTCTTTTGTATGTGGAAAAATGTA TTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATATATTAGCGTAACACTTCACTGAATGTGA CGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCTTAATCAGTGTTAATTTCCCAGTGTTTCA GTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCAGCCCTCTCTAGATTGCTGGAATTGTATG GATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGAGTGCAAACCTTTCATAAATATACTTTCC AGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGCGGTCGGGAGTTCGAGACCAGC CTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAAATAGCCAGGTGTGGTGGTGGGTTCCTGT AGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGCAGTGAACTGAGATCACACCACTGTACTC CAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATATATATGTATATATATATACACACACACA CACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCCCCATATCATTTCTGGTAACAGAGCACAG CAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTAAGTGAATGCCGTTGAAAGGTGTTTCATA CACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAACTGGGACTATGTCTTTATGACTGTGATG GTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCAGTGATTAGGAAGACTATAATATGACTTT GTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCCCTGTGATTCAGGCTTATGGAGCGTTAAG AATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGAATTGCTTCCTTTCTGTGATCACTGCTAC TTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCCTGATGGGTTTCCGAACTGGCTGACTTAA CCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGGTCAGCTGCCCCACTCCTGACTTTTTTAT TTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTGACTCCTCACTTGTGAATAATAGGAATAT ATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTATAGTATCTGGTGTAAACAAATTTTATTC AGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAGTTTTTCTCTTGTGGTGGCTTAAAACGCT GATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGTTCTCATGTCTTTTTGCAGATTTAAAGGT TTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAAACTGATTAACTTGTGATGGTGATGGTGA TTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACTTGTGAGGTATGGTATCCATTATCAACAG TGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATTTGGCACTTAATATAAATCCATTTGATTT GAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGGGAAACTGATTCTACAAATATCTTATATA GAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAATCACTGGCTTTGGTGTTATGTAGAGATAT TTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGTAATTTTGTTGTATGGACTTTTAAAATAT >In-frame_MDM2_ENST00000258148_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6159nt ATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAA GAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTT TTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGAT TTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAG GTCAGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCAAACAATCTTA ATAAACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGAAGAGCGGAAA GATCATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTTAGTTGTACAG TAAGAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAATAAAGGCAGAT TGAGTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGTTTGTTTTCAC AGCTTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTGGTGGATGTTG ACTTAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGAGACCCCTGCC AAGCCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGATGTATTTTAA CCTCAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAGGATTGGAGAT TGCTCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTTTTTTTTTTTC TTTTGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATCCTCAGGAACA ATTAGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATCTGAAATCTGT TGTGTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGGAGTTTCAGAA GGTGTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGTGGCTGATGCC TGTAATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCCG TCTCTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGA ACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAA AAAAAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTACCCTGGCAACC CGCTCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTCAGTTTGGAGA AGATTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGCAGATGTTTTT GTGGATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATTCACTTCCTGA AACGTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGGCTCACCCCTA TAATCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGAAACCCCGTCT CTACTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCGCTTGAAC ATGGGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAAAAAAATTATT TGCTGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGCTC CGCCTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCTAATTTTTTAT ATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTG CTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGGTTGAAATCAT TCTAGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCTTCTTTCCTTT TGTGCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCGCAAAGCTAAT GATCGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTGGGCTGGGTGT AATACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATCATCATTTTAA CTTGTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGTCGAAAATATG CACTATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGTCTTCATTTTT AATGAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATAGAAATCCTAG ATGCTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGGGGATTTTTTT GTTCCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTTTTCTCTCTTT TGTATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATATATTAGCGTA ACACTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCTTAATCAGTGT TAATTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCAGCCCTCTCTA GATTGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGAGTGCAAACCT TTCATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGCGGT CGGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAAATAGCCAGGT GTGGTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGCAGTGAACTGA GATCACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATATATATGTATA TATATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCCCCATATCATT TCTGGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTAAGTGAATGCC GTTGAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAACTGGGACTAT GTCTTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCAGTGATTAGGA AGACTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCCCTGTGATTCA GGCTTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGAATTGCTTCCT TTCTGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCCTGATGGGTTT CCGAACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGGTCAGCTGCCC CACTCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTGACTCCTCACT TGTGAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTATAGTATCTGG TGTAAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAGTTTTTCTCTT GTGGTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGTTCTCATGTCT TTTTGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAAACTGATTAAC TTGTGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACTTGTGAGGTAT GGTATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATTTGGCACTTAA TATAAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGGGAAACTGATT CTACAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAATCACTGGCTTT GGTGTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGTAATTTTGTTG >In-frame_MDM2_ENST00000350057_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6066nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAGGTC AGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCAAACAATCTTAATA AACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGAAGAGCGGAAAGAT CATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTTAGTTGTACAGTAA GAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAATAAAGGCAGATTGA GTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGTTTGTTTTCACAGC TTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTGGTGGATGTTGACT TAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGAGACCCCTGCCAAG CCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGATGTATTTTAACCT CAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAGGATTGGAGATTGC TCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTTTTTTTTTTTCTTT TGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATCCTCAGGAACAATT AGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATCTGAAATCTGTTGT GTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGGAGTTTCAGAAGGT GTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGTGGCTGATGCCTGT AATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCCGTCT CTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACC TGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAAAAA AAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTACCCTGGCAACCCGC TCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTCAGTTTGGAGAAGA TTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGCAGATGTTTTTGTG GATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATTCACTTCCTGAAAC GTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGGCTCACCCCTATAA TCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGAAACCCCGTCTCTA CTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCGCTTGAACATG GGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAAAAAAATTATTTGC TGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGCTCCGC CTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCTAATTTTTTATATT TTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTG GGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGGTTGAAATCATTCT AGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCTTCTTTCCTTTTGT GCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCGCAAAGCTAATGAT CGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTGGGCTGGGTGTAAT ACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATCATCATTTTAACTT GTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGTCGAAAATATGCAC TATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGTCTTCATTTTTAAT GAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATAGAAATCCTAGATG CTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGGGGATTTTTTTGTT CCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTTTTCTCTCTTTTGT ATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATATATTAGCGTAACA CTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCTTAATCAGTGTTAA TTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCAGCCCTCTCTAGAT TGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGAGTGCAAACCTTTC ATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGCGGTCGG GAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAAATAGCCAGGTGTG GTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGCAGTGAACTGAGAT CACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATATATATGTATATAT ATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCCCCATATCATTTCT GGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTAAGTGAATGCCGTT GAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAACTGGGACTATGTC TTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCAGTGATTAGGAAGA CTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCCCTGTGATTCAGGC TTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGAATTGCTTCCTTTC TGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCCTGATGGGTTTCCG AACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGGTCAGCTGCCCCAC TCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTGACTCCTCACTTGT GAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTATAGTATCTGGTGT AAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAGTTTTTCTCTTGTG GTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGTTCTCATGTCTTTT TGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAAACTGATTAACTTG TGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACTTGTGAGGTATGGT ATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATTTGGCACTTAATAT AAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGGGAAACTGATTCTA CAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAATCACTGGCTTTGGT GTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGTAATTTTGTTGTAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MDM2_ENST00000462284_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6547nt GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT ACAGGAACTTGGTAGTAGTCAATCAGCAGGTGGAGCACCTGGAGAAGCAGGTCAGACTGCTCAACATCCGTCTCAACCGGGTGCTCGAGA GCCTGGACCGCTCCAAGGACAAGTGAAGGTCAGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGA AAAAAACCCCAAACCCCAAACAATCTTAATAAACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTC TTAGGACACATTCCCAGAAGAGCGGAAAGATCATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACA AAGGATATAACCATATTTAGTTGTACAGTAAGAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCT TTTGTAAGGTTTTTTAATAAAGGCAGATTGAGTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAA AAGTTTAAATGCGAGCGTTTGTTTTCACAGCTTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTT TATTTCATGTTATTTTTGGTGGATGTTGACTTAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAA CCTCTTTTGGATCCTAGAGACCCCTGCCAAGCCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTT CTTCCCTCTGTGCTTCGATGTATTTTAACCTCAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGC CAGGAAGTACCTGGTAAGGATTGGAGATTGCTCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGC TATACCCTTGAGGGTTTTTTTTTTTTTCTTTTGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATA TTGCTGCTTAGAAAGATCCTCAGGAACAATTAGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGAT ACACAGGTGCTTTTTATCTGAAATCTGTTGTGTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGT GGGGATCCTGGGCAAGGGAGTTTCAGAAGGTGTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAG CCCTAGGCCAGGCGCAGTGGCTGATGCCTGTAATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGAC CAGCCTGGCCAACATGGTGAAACCCCCGTCTCTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTC AGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACA GAGCAAGACTTCATCTTAAAAAAAAAAAAAAAAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTT ACCTGGCCACAGATGTACCCTGGCAACCCGCTCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGA CCTTATGGTCCAGGTCTCAGTTTGGAGAAGATTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAG TATCTGGAAAACAGATGCAGATGTTTTTGTGGATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACT CTCCTGGAGAGTTCCATTCACTTCCTGAAACGTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGA GCAGGCTGGGCAGGGTGGCTCACCCCTATAATCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCA GCCCGGCCAACAGAGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGG GAGGCTGAGGCTGGAGAATCGCTTGAACATGGGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGA GTGAGACTCCGTCTCAAAAAAAATTATTTGCTGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAG TGGCACCATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGC CCACCATCATGCCCGGCTAATTTTTTATATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGT GATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTG GAACACAGGATTACTGGGTTGAAATCATTCTAGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTC GGGAGGTCATCTCTATCTTCTTTCCTTTTGTGCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAA AACATGGCATTCTGTGCGCAAAGCTAATGATCGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTA AGGCTTAAGCTGTCACTGGGCTGGGTGTAATACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTAT TGAGATCTCGATAAGATCATCATTTTAACTTGTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCA TCAATTCAAAATTGCTGTCGAAAATATGCACTATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATA CATTCTGGTGAAAGATGTCTTCATTTTTAATGAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGA TTATTTGAAACTCTGATAGAAATCCTAGATGCTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATC TTACCCCAAAATAATTGGGGATTTTTTTGTTCCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCG CCACATGTCTTTGTTTTTTTCTCTCTTTTGTATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTAT CTTCAGGGCTGTAGAATATATTAGCGTAACACTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGAC TCAGTGTTTAAAATATCTTAATCAGTGTTAATTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCC AGAAAAGGAAAAGGACCAGCCCTCTCTAGATTGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAG CAAAGATGCTTTTGTGGAGTGCAAACCTTTCATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGG AGGCCAAGGCGGGTGGATCACTTGCGGTCGGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAA AAAAAAAAAAAAAAAAAAATAGCCAGGTGTGGTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAAC CTGGGAGGCAGAGGTTGCAGTGAACTGAGATCACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAA AGTGTGTGTGTGTGTATATATATGTATATATATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTT TGCTTTGGATTTCAGCCCCCATATCATTTCTGGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGT CTTAATTCACAAAGGGTAAGTGAATGCCGTTGAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGA GGCAGCGATGTCAGGGAACTGGGACTATGTCTTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGA ACGCAAAGGTTTGGGTCAGTGATTAGGAAGACTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGC TTAGTCGCTCATCTGGCCCTGTGATTCAGGCTTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGT TGCTAGTGGAAATCCTGAATTGCTTCCTTTCTGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGA CACCTGATAACTTCTCCCTGATGGGTTTCCGAACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATT CCTGAGGCTCCTAAGGGGTCAGCTGCCCCACTCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCAT TTGAATAGTTGGACTTTGACTCCTCACTTGTGAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGAC AACCATCAGTGTGATGTATAGTATCTGGTGTAAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAG GAGGTGCACCAGTACCAGTTTTTCTCTTGTGGTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTG GTATTATTGACCATGTGTTCTCATGTCTTTTTGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTC TGAATACCATGTAATTAAACTGATTAACTTGTGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTC TTAACTGGAAATCACACTTGTGAGGTATGGTATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAAT TTTGTATAGCATTTAATTTGGCACTTAATATAAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTT TAGTTTCGTGAGCCTTGGGAAACTGATTCTACAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACAT TCCTCTTATTTATTAAATCACTGGCTTTGGTGTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGC >In-frame_MDM2_ENST00000258149_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6532nt GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG TAGTCAATCAGCAGGTGGAGCACCTGGAGAAGCAGGTCAGACTGCTCAACATCCGTCTCAACCGGGTGCTCGAGAGCCTGGACCGCTCCA AGGACAAGTGAAGGTCAGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACC CCAAACAATCTTAATAAACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCC AGAAGAGCGGAAAGATCATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATA TTTAGTTGTACAGTAAGAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTT AATAAAGGCAGATTGAGTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAG CGTTTGTTTTCACAGCTTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTT TTGGTGGATGTTGACTTAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCT AGAGACCCCTGCCAAGCCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTT CGATGTATTTTAACCTCAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGT AAGGATTGGAGATTGCTCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGT TTTTTTTTTTTTCTTTTGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAG ATCCTCAGGAACAATTAGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTT ATCTGAAATCTGTTGTGTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAA GGGAGTTTCAGAAGGTGTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGC AGTGGCTGATGCCTGTAATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT GGTGAAACCCCCGTCTCTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAG GAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATC TTAAAAAAAAAAAAAAAAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATG TACCCTGGCAACCCGCTCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGT CTCAGTTTGGAGAAGATTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGA TGCAGATGTTTTTGTGGATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCC ATTCACTTCCTGAAACGTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGG TGGCTCACCCCTATAATCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAG TGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGA GAATCGCTTGAACATGGGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTC AAAAAAAATTATTTGCTGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGC TCACTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCG GCTAATTTTTTATATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCG GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACT GGGTTGAAATCATTCTAGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTA TCTTCTTTCCTTTTGTGCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGT GCGCAAAGCTAATGATCGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCA CTGGGCTGGGTGTAATACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAG ATCATCATTTTAACTTGTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGC TGTCGAAAATATGCACTATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGA TGTCTTCATTTTTAATGAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTG ATAGAAATCCTAGATGCTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAAT TGGGGATTTTTTTGTTCCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTT TTTTTCTCTCTTTTGTATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGA ATATATTAGCGTAACACTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATA TCTTAATCAGTGTTAATTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGA CCAGCCCTCTCTAGATTGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGT GGAGTGCAAACCTTTCATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTG GATCACTTGCGGTCGGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAA AAAATAGCCAGGTGTGGTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGT TGCAGTGAACTGAGATCACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGT ATATATATGTATATATATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAG CCCCCATATCATTTCTGGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGG GTAAGTGAATGCCGTTGAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGG GAACTGGGACTATGTCTTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGG TCAGTGATTAGGAAGACTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTG GCCCTGTGATTCAGGCTTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCC TGAATTGCTTCCTTTCTGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCT CCCTGATGGGTTTCCGAACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAG GGGTCAGCTGCCCCACTCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACT TTGACTCCTCACTTGTGAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGAT GTATAGTATCTGGTGTAAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTAC CAGTTTTTCTCTTGTGGTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATG TGTTCTCATGTCTTTTTGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAAT TAAACTGATTAACTTGTGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCAC ACTTGTGAGGTATGGTATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTA ATTTGGCACTTAATATAAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCT TGGGAAACTGATTCTACAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTA AATCACTGGCTTTGGTGTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTAT >In-frame_MDM2_ENST00000258148_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6259nt CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG TCAATCAGCAGGTGGAGCACCTGGAGAAGCAGGTCAGACTGCTCAACATCCGTCTCAACCGGGTGCTCGAGAGCCTGGACCGCTCCAAGG ACAAGTGAAGGTCAGCCGGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCA AACAATCTTAATAAACACGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGA AGAGCGGAAAGATCATTGACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTT AGTTGTACAGTAAGAGAAATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAAT AAAGGCAGATTGAGTCAAGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGT TTGTTTTCACAGCTTAGGGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTG GTGGATGTTGACTTAGTTCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGA GACCCCTGCCAAGCCCCCATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGA TGTATTTTAACCTCAACATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAG GATTGGAGATTGCTCCAGAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTT TTTTTTTTTCTTTTGATTTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATC CTCAGGAACAATTAGCAGCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATC TGAAATCTGTTGTGTCCTCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGG AGTTTCAGAAGGTGTGGCTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGT GGCTGATGCCTGTAATCCCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGT GAAACCCCCGTCTCTACTAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAG AATTGCTTGAACCTGGGAGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTA AAAAAAAAAAAAAAAGCCCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTAC CCTGGCAACCCGCTCACAGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTC AGTTTGGAGAAGATTTAGCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGC AGATGTTTTTGTGGATGTTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATT CACTTCCTGAAACGTGCACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGG CTCACCCCTATAATCCCAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGA AACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAA TCGCTTGAACATGGGAGGCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAA AAAAATTATTTGCTGGATCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCA CTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCT AATTTTTTATATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCC TCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGG TTGAAATCATTCTAGTTTTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCT TCTTTCCTTTTGTGCATTTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCG CAAAGCTAATGATCGCCAGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTG GGCTGGGTGTAATACCCGCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATC ATCATTTTAACTTGTATTCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGT CGAAAATATGCACTATTTTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGT CTTCATTTTTAATGAAAGAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATA GAAATCCTAGATGCTAGATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGG GGATTTTTTTGTTCCTTCTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTT TTCTCTCTTTTGTATGTGGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATA TATTAGCGTAACACTTCACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCT TAATCAGTGTTAATTTCCCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCA GCCCTCTCTAGATTGCTGGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGA GTGCAAACCTTTCATAAATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGAT CACTTGCGGTCGGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAA ATAGCCAGGTGTGGTGGTGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGC AGTGAACTGAGATCACACCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATA TATATGTATATATATATACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCC CCATATCATTTCTGGTAACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTA AGTGAATGCCGTTGAAAGGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAA CTGGGACTATGTCTTTATGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCA GTGATTAGGAAGACTATAATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCC CTGTGATTCAGGCTTATGGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGA ATTGCTTCCTTTCTGTGATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCC TGATGGGTTTCCGAACTGGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGG TCAGCTGCCCCACTCCTGACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTG ACTCCTCACTTGTGAATAATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTA TAGTATCTGGTGTAAACAAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAG TTTTTCTCTTGTGGTGGCTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGT TCTCATGTCTTTTTGCAGATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAA ACTGATTAACTTGTGATGGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACT TGTGAGGTATGGTATCCATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATT TGGCACTTAATATAAATCCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGG GAAACTGATTCTACAAATATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAAT CACTGGCTTTGGTGTTATGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGT >In-frame_MDM2_ENST00000350057_chr12_69214154_+_BRI3BP_ENST00000341446_chr12_125509890_+_6152nt ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGTGGAG CACCTGGAGAAGCAGGTCAGACTGCTCAACATCCGTCTCAACCGGGTGCTCGAGAGCCTGGACCGCTCCAAGGACAAGTGAAGGTCAGCC GGCCGGGCGGGTCCACAGTTACCAGCACGCTGTCTCAGAAAACGAAAACGGAGGAAAAAAACCCCAAACCCCAAACAATCTTAATAAACA CGACTGAGCAAGAAAGTGGCGCTGTGTAGGGCTATTTCCACCCACCCGGCAGCTCTTAGGACACATTCCCAGAAGAGCGGAAAGATCATT GACGTGGAACTACACACGAAGTGTAATTAGTGGGGGAAAAAATATTTTTTAAACAAAGGATATAACCATATTTAGTTGTACAGTAAGAGA AATTTATCTGTGCATAGAGCATAAAGTTAATTTTTTCAAGCATTTAAATACATCTTTTGTAAGGTTTTTTAATAAAGGCAGATTGAGTCA AGTTTATTAAAACTTTACATGGAGGGGAAGAATATGCTAATTTGACATTTGAGAAAAGTTTAAATGCGAGCGTTTGTTTTCACAGCTTAG GGATTGGTGGGTGAGGTCTGTGTGCGTTATTTTCATGTTCCCAAACTGTGAGCTTTATTTCATGTTATTTTTGGTGGATGTTGACTTAGT TCATGAATGTTGTCACTTCTAAATGTGGACAGTTGGGCTGCAGGATGCAACTCAACCTCTTTTGGATCCTAGAGACCCCTGCCAAGCCCC CATCAGTCCTATTTTTAAATGAAGACATCGCCATTTCTAGAAGACCTGAGATTTTCTTCCCTCTGTGCTTCGATGTATTTTAACCTCAAC ATTTTGAAACGGAAAATGCAAGGAGGGGCCAAGAAATGTCCTGGGGATTTGATGCCAGGAAGTACCTGGTAAGGATTGGAGATTGCTCCA GAATCTACTGCATGTCCCAATTTGCAGTTTGCTCACTAGGGCTATATACAAAAGCTATACCCTTGAGGGTTTTTTTTTTTTTCTTTTGAT TTCCTCAGGACCTTAGAGGGAAAACAAACAGTAGCAGCTAATATTCTCAAGTATATTGCTGCTTAGAAAGATCCTCAGGAACAATTAGCA GCAATAAGCAAGCCTTTGAAAAGATCTGAATTCTTTTTCCTGAAATATTTACGATACACAGGTGCTTTTTATCTGAAATCTGTTGTGTCC TCCTTTTAGGCAGTCTCTGTGGGCAGAGAGTGGGACTTGCGAGGTGGACAGCTGTGGGGATCCTGGGCAAGGGAGTTTCAGAAGGTGTGG CTCAGGGGCTGGTAGAAACCCCCTTTTGTTAGGACTTGTTTTTTAAAAAAGAAAGCCCTAGGCCAGGCGCAGTGGCTGATGCCTGTAATC CCAGCGCTTTGGGAGGCCGAGGAGTATGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCCGTCTCTAC TAAAAATACAAAAATTAGTCAGGCATGGTGGTGGGTGCCTGTAGTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGG AGGTGGAGGTTGCGGTGAGCCGAGATCACGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGACTTCATCTTAAAAAAAAAAAAAAAAGC CCAGCATTTTGCAGCTTTGAAGCTGCTGGGGATCACGACTGTCTCTGTGGCCCTTACCTGGCCACAGATGTACCCTGGCAACCCGCTCAC AGTGCCCTGCGTGCAGGTTTATAGATAACCCCTGCCAGACCTGCTACAACCAAGACCTTATGGTCCAGGTCTCAGTTTGGAGAAGATTTA GCTGTCTACCACTTCTTGTGTAGTGTTCCTGTGAAGTTTTATTTTTGGTTGCAAGTATCTGGAAAACAGATGCAGATGTTTTTGTGGATG TTGTTGAGACTTTTGAGACTTCTGTTTCTAAGGTACACATGATGGGACCCAAACTCTCCTGGAGAGTTCCATTCACTTCCTGAAACGTGC ACCTGTTTCAGGTGCATGTTTATTCAGTGTGCATGGATATTTAAGATTTGCTGGAGCAGGCTGGGCAGGGTGGCTCACCCCTATAATCCC AACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCCGGCCAACAGAGTGAAACCCCGTCTCTACTAA AAATACAAAAATTAGCCAGGCCTGGTGGTGGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCGCTTGAACATGGGAG GCGGAGGTTGCAGTCAGCTGAGATCATACCACCACACTCTAGCCTCAGCAACAGAGTGAGACTCCGTCTCAAAAAAAATTATTTGCTGGA TCGAATCTTTTTTTTTTTGAGATGGAGTCTCACTGTCAACCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGCTCCGCCTCC TGGGTTCACGCCATTCTCCTACCTCAGCCTCCCAAGTAGCCGGGACTACAGGCGCCCACCATCATGCCCGGCTAATTTTTTATATTTTTA GTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGAT TACAGGCGTGAGCCACCGCGCTGGGCCTAGATCAAATCTTTATCCATGCACATTGGAACACAGGATTACTGGGTTGAAATCATTCTAGTT TTGTCATTTAGATACTTGTAGATGAATCTATTTTAGCACAAGGTATAAATAACTCGGGAGGTCATCTCTATCTTCTTTCCTTTTGTGCAT TTGGCTATACCACGTTTAGGTACTAAAACAGCTTTGCTTATGTTGGCCAGGGGAAAACATGGCATTCTGTGCGCAAAGCTAATGATCGCC AGCCCTGCCTTGGCCCCTCCCTTGTTTATGGTCATTGTAAGATGCCCGCATGTTAAGGCTTAAGCTGTCACTGGGCTGGGTGTAATACCC GCTTCATTCCTCCTCCCACCCTCTTACCCGAAACATGAAGGGCACTGTGCTCTATTGAGATCTCGATAAGATCATCATTTTAACTTGTAT TCAACTGAGGGAGGTAACATGATATCTGGGTGCTGGTGGATTGAGACCTCAAGCATCAATTCAAAATTGCTGTCGAAAATATGCACTATT TTTTTTTTCCACTCTGGCTAAGTGTAGGCTCTGAAGCCAGTTTTATAGCTTGATACATTCTGGTGAAAGATGTCTTCATTTTTAATGAAA GAACCTACAGTTAGTAGGTGTCACCTCAGGGTAGAAATTCTGATAGAAATTCTGATTATTTGAAACTCTGATAGAAATCCTAGATGCTAG ATTTGAAGAAAACCTGGGTTTTATTGCATAGATTTCACCTTTTCTGGGGCACATCTTACCCCAAAATAATTGGGGATTTTTTTGTTCCTT CTCCATTCCATGGAACCTTGTAGGGTGTTGGGATTGGGCCTCCCCTCGCCACCCGCCACATGTCTTTGTTTTTTTCTCTCTTTTGTATGT GGAAAAATGTATTTTTGTACCATATCTCATACCTGGAGAGAAACCTTTTTTCTATCTTCAGGGCTGTAGAATATATTAGCGTAACACTTC ACTGAATGTGACGTAAAAGCATTCTGATGAAAACTGGTTCTGTTATAATTAAGACTCAGTGTTTAAAATATCTTAATCAGTGTTAATTTC CCAGTGTTTCAGTATCACAGTAAATACTTGTTTTACTGAGAACAGAAAATAATCCAGAAAAGGAAAAGGACCAGCCCTCTCTAGATTGCT GGAATTGTATGGATGTGTTGGGGTTGGTTTAGTGATCTCTTCCTTGACACCCTAGCAAAGATGCTTTTGTGGAGTGCAAACCTTTCATAA ATATACTTTCCAGGCTGGGTGCAGTGGCTCAAGCTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGCGGTCGGGAGT TCGAGACCAGCCTGGCCAACATAGTGAAATCCCGTCTCTACCAAAAAATACAAAAAAAAAAAAAAAAAAAAAAATAGCCAGGTGTGGTGG TGGGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTGTATGAACCTGGGAGGCAGAGGTTGCAGTGAACTGAGATCACA CCACTGTACTCCAGTTGAGGCGACAGAGTGAGACCCAGTCTCAAAAAAAAAAAAAAGTGTGTGTGTGTGTATATATATGTATATATATAT ACACACACACACACTTTCCAATACCAGTCGGCATTACCCGCCCTTTGGTTTCTTTTGCTTTGGATTTCAGCCCCCATATCATTTCTGGTA ACAGAGCACAGCAATAGAATTTCTGGGAAGCAGACCTTGTGAATCGTGCCTGTGTCTTAATTCACAAAGGGTAAGTGAATGCCGTTGAAA GGTGTTTCATACACTTACCCCAGAAATGAGAGCCTGTCTCATGCAGGAGTCGGGAGGCAGCGATGTCAGGGAACTGGGACTATGTCTTTA TGACTGTGATGGTGGTAACCAAGTGGGGTGGTCCCCTCTGGGGAGCTGAGTAAGAACGCAAAGGTTTGGGTCAGTGATTAGGAAGACTAT AATATGACTTTGTGCATGCCCGGGAGGGCTGCCTTGTAGAGAGGATGTGAGCAGCTTAGTCGCTCATCTGGCCCTGTGATTCAGGCTTAT GGAGCGTTAAGAATAACAGCTGTCAAATGGCCTAGACATGGTTAATGCAATTTGTTGCTAGTGGAAATCCTGAATTGCTTCCTTTCTGTG ATCACTGCTACTTCTTAAGATGCTTTTGATGAATGTCATCTGCCTTACAAGTTGACACCTGATAACTTCTCCCTGATGGGTTTCCGAACT GGCTGACTTAACCAAAAAGCCAGCTCTTGCCATCTATCTTGCATTAAAAGGAATTCCTGAGGCTCCTAAGGGGTCAGCTGCCCCACTCCT GACTTTTTTATTTTTAATGGTCTATACCTTCTGCAACATTTTTGTTTATGGCCATTTGAATAGTTGGACTTTGACTCCTCACTTGTGAAT AATAGGAATATATTTTGCAGAATCTAACATAATACCCTTAAAATTCATACTGGACAACCATCAGTGTGATGTATAGTATCTGGTGTAAAC AAATTTTATTCAGCATATTAAATTATTCTGTGTTTTGCTTTTCCTTGATATGTAGGAGGTGCACCAGTACCAGTTTTTCTCTTGTGGTGG CTTAAAACGCTGATTGCCATTTGCATTGTCTACTGAAAAGCTGTGGCAGCGAGTGGTATTATTGACCATGTGTTCTCATGTCTTTTTGCA GATTTAAAGGTTTTATTGTAGTGTCCATTTAATATCTGCATGTGTGTTTAATCTCTGAATACCATGTAATTAAACTGATTAACTTGTGAT GGTGATGGTGATTAGCACACACTAAAAACCCAATGAAGCAATTGTCTCCCTCTTCTTAACTGGAAATCACACTTGTGAGGTATGGTATCC ATTATCAACAGTGGATTCATGATTGACTTCATATTTTGTGTATCTGGTTATAAATTTTGTATAGCATTTAATTTGGCACTTAATATAAAT CCATTTGATTTGAATAGTGTGTGTGTGTACATGGTGTGTGTGTGTGTGTGCACTTTAGTTTCGTGAGCCTTGGGAAACTGATTCTACAAA TATCTTATATAGAGATAAATGTATCAGGCATTTTTTTGCAAAGCGATATATACATTCCTCTTATTTATTAAATCACTGGCTTTGGTGTTA TGTAGAGATATTTGTAGATCTCAGAACAGAATTAAAATATTGTGAAAATTACAGCTTAATAAATGTTTATTGTAATTTTGTTGTATGGAC |
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FusionGenePPI for MDM2_BRI3BP |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MDM2 | TP53, MDC1, CTBP1, CTBP2, TP73, PML, RPL11, RPL5, CDKN2A, NUMB, UBE2A, HIF1A, KAT5, HDAC1, EID1, MDM4, KAT2B, EP300, TBP, TAF1, MDM2, ESR1, ARRB2, ABL1, CCNG1, ARRB1, TSG101, RB1, MTBP, FKBP3, RYBP, RRM2B, RPL26, GNAS, FOXO4, IGF1R, DAXX, DHFR, GNL3, CCAR1, PSMD10, PSME3, PTK2, AR, PPM1D, USP7, COPS5, SFN, RBBP6, CDH1, CHEK2, YWHAQ, NCL, UBE2G2, UBE2U, UBE2Z, PYHIN1, BANP, DDX17, E2F1, TRIM28, UBC, GATA3, ATF3, HIST2H2BE, RPL23, YY1, AKT1, RAD23A, CDKN1A, NR3C1, UBE2I, HIST3H3, EHMT1, SUV39H1, RPS27L, RPS27, ADRB2, SIVA1, MTA1, RCHY1, UBE2D1, CASP2, RPS27A, RPS7, G3BP2, PSMD2, PAK1IP1, RPS6KB1, ZNF668, TP63, PCNA, USP10, PSMC1, PSMD4, PSMC3, PSMC5, PSMC6, PSMA7, PSMD1, RUNX3, GNL3L, TERT, APEX1, UIMC1, CREBBP, SOX4, UBE4B, TBRG1, BAIAP2L1, RFWD3, ERBB3, PA2G4, HEXIM1, CDK9, DYRK2, HSP90AA1, HSPA4, HSPA8, LAMP2, RPS3, USP2, TRIM13, XRCC6, GORAB, FOXO1, FOXO3, UCHL1, S100A1, S100A2, S100A4, S100A6, S100B, USP42, CUL1, BTRC, FBXW11, CSNK1D, RFWD2, SMURF1, NOTCH4, CSNK1A1, PDLIM7, SENP3, RN5S1@, PDE4D, NOTCH1, SNAI1, RASSF1, TRIM27, RFFL, RPS14, PPP2R4, TTF1, PSMB6, PSMA8, RASSF3, NR0B2, UBE2B, PIAS1, RANBP1, LATS1, RAD50, NBN, MRE11A, CUL4A, DTL, PIM1, GSK3B, PSMA3, ESR2, ADRBK1, AATF, HNRNPK, BUB1B, SUMO1, RASSF5, UBE2D2, POLH, NPM1, TCAP, CDK5RAP3, ARIH2, IRF2, RPS25, TPT1, ANG, RHOA, PDCD5, CDKN2AIP, LATS2, WWOX, MED1, ERCC6, ERCC8, DDB1, CUL4B, HIPK2, DHRS2, CASP3, ITCH, EEF1A1, DCD, TUBB, TUBB2A, KRT14, RPS20, GAPDH, TUBA1C, GSN, ERBB4, XIAP, HNF4A, PLK1, NME2, NEDD4, DAPK1, DAPK3, ATM, PBX1, UBE2D3, UBE3A, UBE2L3, UBE2E2, UBE2E3, RNF2, EGR1, PAK6, DLG4, IRF1, VCP, STRA13, GADD45A, RABL6, RPS26, RPL37, RPS15, RNF8, TRIM4, TRIM23, TRAF5, TRIM9, MKRN3, PHF7, RNF10, RNF126, UBE2K, LMO7, HLA-DMB, SETDB1, YY1AP1, NACA, ATF4, MYD88, RELA, SDHC, WT1, SORBS2, HRSP12, DNAJB4, GCAT, SHPK, POT1, ANKRD17, GLTSCR2, SESN2, RASSF6, JUND, EZR, RYR2, JUN, CLSTN1, APP, CLU, SREK1, SET, HSP90B1, CWC25, ZNF133, PKM, TAB1, RPL6, AURKA, NOC2L, JAK1, XPC, PGAM1, PGAM2, DNAJB1, ANAPC2, NLK, SNAI2, RBM38, FHIT, AGPS, ALDH16A1, DDX5, DHX9, DLAT, EDC4, EIF2AK1, ESYT1, GTF2I, HMHA1, HNRNPM, HNRNPU, HRNR, HSP90AB1, IARS, IFI16, IGF2BP3, ILF3, KARS, CCAR2, NEK9, OGDH, OGDHL, RARS, RBBP8, RECQL, SF3B1, SFPQ, TOP1, ZNF318, PER2, SIRT6, TSC22D3, RPS6, UBE2M, RAD54B, SMARCA2, ACACA, PTBP1, IYD, ACTB, HNRNPD, U2AF2, FUBP1, TFRC, EEF2, XPO1, KRT2, EIF3B, SND1, DCAF8, USO1, EFTUD2, EXOSC6, IPO7, SF3B3, DET1, UBE2N, RPL10A, DIRAS3, SURF2, RFPL2, CMSS1, PPARD, RPL22L1, IER2, MAGEA2, ZNF420, ELF4, ABL2, SRC, HCK, GTF2E2, ATP2A2, BRINP1, C19orf10, CANX, MS4A1, PDIA3, PPIB, RAB8A, RPS23, RUVBL2, SMARCA4, SMARCE1, SRSF11, TPR, UBTF, PPARG, VDR, FBXO31, TFIP11, SETD7, PPP1CA, RARA, DDX24, NAT10, CCND1, RLIM, IER3, FHL2, RPL23A, SUZ12, EZH2, EED, RRM1, RPL4, NOLC1, DDX42, MAP2, NUCKS1, RRP1, PDS5A, RPL36A, TP53RK, RPL15, NPIPB3, HMGN1, MAP1LC3A, PRDM2, KIAA1551, PBXIP1, SP1, SHARPIN, MAPKAPK2, USP15, USP26, FKBP1A, NGFR, SMG7, RSL1D1, SIRT1, SIRT7, SIRT2, SIRT3, KPNA1, KPNA6, MSI2, PHLDB3, CLPB, XAGE1B, ZNF550, YAF2, PDGFB, ARNTL2, RPS11, TSPYL6, HIST1H2BJ, ZNF764, MAK16, ZNF274, PPAN, RPL37A, CRTC2, CRTC3, TRIM25, CSNK2A1, CSNK2B, CSNK2A2, HEY1, RANBP2 | BRI3BP | ESR1, RNF2, AMFR, TSPAN5, GDE1, PTH1R, P2RY12, DLK1, ZACN, HTR3C, TUSC5, LCA5, TCTN2, TCTN3, TCTN1, SPPL2B, YIPF3, LPAR1, LRRC4C, TPTE, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 170_306 | 113 | 437 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 170_306 | 0 | 322 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 170_306 | 0 | 266 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 170_306 | -102 | 322 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 170_306 | 0 | 297 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 170_306 | -92 | 219 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 170_306 | 0 | 219 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 170_306 | -102 | 271 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 170_306 | 119 | 498 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 170_306 | -102 | 297 | MTBP |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 150_230 | 113 | 437 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 150_230 | 0 | 322 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 150_230 | 0 | 266 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 150_230 | -102 | 322 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 150_230 | 0 | 297 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 150_230 | -92 | 219 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 150_230 | 0 | 219 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 150_230 | -102 | 271 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 150_230 | 119 | 498 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 150_230 | -102 | 297 | PYHIN1 and necessary for interaction with RFFL and RNF34 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000258149 | + | 5 | 9 | 223_232 | 113 | 437 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000299252 | + | 1 | 5 | 223_232 | 0 | 322 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000348801 | + | 1 | 3 | 223_232 | 0 | 266 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000356290 | + | 1 | 6 | 223_232 | -102 | 322 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000360430 | + | 1 | 4 | 223_232 | 0 | 297 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393412 | + | 1 | 3 | 223_232 | -92 | 219 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000393413 | + | 1 | 2 | 223_232 | 0 | 219 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000428863 | + | 1 | 4 | 223_232 | -102 | 271 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000462284 | + | 5 | 11 | 223_232 | 119 | 498 | USP7 |
| Hgene | MDM2 | chr12:69214154 | chr12:125509890 | ENST00000540827 | + | 1 | 5 | 223_232 | -102 | 297 | USP7 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for MDM2_BRI3BP |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | MDM2 | Q00987 | DB01593 | Zinc | E3 ubiquitin-protein ligase Mdm2 | small molecule | approved|investigational |
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RelatedDiseases for MDM2_BRI3BP |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MDM2 | C0007131 | Non-Small Cell Lung Carcinoma | 2 | CTD_human |
| Hgene | MDM2 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Hgene | MDM2 | C0019693 | HIV Infections | 1 | CTD_human |
| Hgene | MDM2 | C0021364 | Male infertility | 1 | CTD_human |
| Hgene | MDM2 | C0025202 | melanoma | 1 | CTD_human |
| Hgene | MDM2 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Hgene | MDM2 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | MDM2 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
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