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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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Fusion gene ID: 2115

FusionGeneSummary for APAF1_TMPO

check button Fusion gene summary
Fusion gene informationFusion gene name: APAF1_TMPO
Fusion gene ID: 2115
HgeneTgene
Gene symbol

APAF1

TMPO

Gene ID

317

7112

Gene nameapoptotic peptidase activating factor 1thymopoietin
SynonymsAPAF-1|CED4CMD1T|LAP2|LEMD4|PRO0868|TP
Cytomap

12q23.1

12q23.1

Type of geneprotein-codingprotein-coding
Descriptionapoptotic protease-activating factor 1thymopoietinLEM domain containing 4TP alphaTP beta/gammalamina-associated polypeptide 2thymopoietin betathymopoietin-related peptide isoform alphathymopoietin-related peptide isoforms beta/gamma
Modification date2018052720180522
UniProtAcc

O14727

P42167

Ensembl transtripts involved in fusion geneENST00000551964, ENST00000339433, 
ENST00000359972, ENST00000333991, 
ENST00000357310, ENST00000552268, 
ENST00000550527, ENST00000547045, 
ENST00000549007, ENST00000547743, 
ENST00000547666, 		ENST00000556029, 
ENST00000343315, ENST00000266732, 
ENST00000393053, ENST00000261210, 
ENST00000548223, 
Fusion gene scores* DoF score3 X 3 X 3=274 X 4 X 3=48
# samples 34
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: APAF1 [Title/Abstract] AND TMPO [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAPAF1

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

21827945

HgeneAPAF1

GO:0008635

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

9267021


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDOVTCGA-24-2262-01AAPAF1chr12

99056584

+TMPOchr12

98931253

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000551964ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000551964ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000339433ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000339433ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000359972ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000359972ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000333991ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000333991ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000357310ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000357310ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000552268ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000552268ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000550527ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000550527ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000547045ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000547045ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000549007ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000549007ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547743ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547743ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547666ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547666ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+

Top

FusionProtFeatures for APAF1_TMPO


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
APAF1

O14727

TMPO

P42167

May help direct the assembly of the nuclear lamina andthereby help maintain the structural organization of the nuclearenvelope. Possible receptor for attachment of lamin filaments tothe inner nuclear membrane. May be involved in the control ofinitiation of DNA replication through its interaction withNAKAP95. Thymopoietin (TP) and Thymopentin (TP5) may play a rolein T-cell development and function. TP5 is an immunomodulatingpentapeptide.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+7895_98318339Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+72695_983181206Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+72695_983071195Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+62595_983181206Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+62695_983071238Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+72795_983181249Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+6795_98318339Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781_90318339DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261_903181206DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261_903071195DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251_903181206DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261_903071238DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271_903181249DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671_90318339DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78154_161318339Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726154_1613181206Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726154_1613071195Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625154_1613181206Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626154_1613071238Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727154_1613181249Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67154_161318339Nucleotide bindingATP
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732+04558_657-80695Coiled coilOntology_term=ECO:0000250
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732+04109_153-80695DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732+045_48-80695DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732+04190_196-80695MotifNuclear localization signal
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732+0449_108-80695RegionNote=Linker
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26299_371188346RegionNote=Binds lamins B
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26300_374188346RegionNote=NAKAP95-binding C
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29299_371188455RegionNote=Binds lamins B
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29300_374188455RegionNote=NAKAP95-binding C
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26435_454188346Topological domainLumenal
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29435_454188455Topological domainLumenal
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26411_434188346TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29411_434188455TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78104_415318339DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726104_4153181206DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726104_4153071195DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625104_4153181206DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626104_4153071238DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727104_4153181249DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67104_415318339DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78910_921318339RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726910_9213181206RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726910_9213071195RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625910_9213181206RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626910_9213071238RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727910_9213181249RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67910_921318339RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781001_1040318339RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781042_1080318339RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781083_1122318339RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781125_1164318339RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781175_1212318339RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781213_1248318339RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78613_652318339RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78655_694318339RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78697_738318339RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78741_780318339RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78796_836318339RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78838_877318339RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78880_910318339RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78922_958318339RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78959_998318339RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261001_10403181206RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261042_10803181206RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261083_11223181206RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261125_11643181206RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261175_12123181206RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261213_12483181206RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726613_6523181206RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726655_6943181206RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726697_7383181206RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726741_7803181206RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726796_8363181206RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726838_8773181206RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726880_9103181206RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726922_9583181206RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726959_9983181206RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261001_10403071195RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261042_10803071195RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261083_11223071195RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261125_11643071195RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261175_12123071195RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261213_12483071195RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726613_6523071195RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726655_6943071195RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726697_7383071195RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726741_7803071195RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726796_8363071195RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726838_8773071195RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726880_9103071195RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726922_9583071195RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726959_9983071195RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251001_10403181206RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251042_10803181206RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251083_11223181206RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251125_11643181206RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251175_12123181206RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251213_12483181206RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625613_6523181206RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625655_6943181206RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625697_7383181206RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625741_7803181206RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625796_8363181206RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625838_8773181206RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625880_9103181206RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625922_9583181206RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625959_9983181206RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261001_10403071238RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261042_10803071238RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261083_11223071238RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261125_11643071238RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261175_12123071238RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261213_12483071238RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626613_6523071238RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626655_6943071238RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626697_7383071238RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626741_7803071238RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626796_8363071238RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626838_8773071238RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626880_9103071238RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626922_9583071238RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626959_9983071238RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271001_10403181249RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271042_10803181249RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271083_11223181249RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271125_11643181249RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271175_12123181249RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271213_12483181249RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727613_6523181249RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727655_6943181249RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727697_7383181249RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727741_7803181249RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727796_8363181249RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727838_8773181249RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727880_9103181249RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727922_9583181249RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727959_9983181249RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671001_1040318339RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671042_1080318339RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671083_1122318339RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671125_1164318339RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671175_1212318339RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671213_1248318339RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67613_652318339RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67655_694318339RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67697_738318339RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67741_780318339RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67796_836318339RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67838_877318339RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67880_910318339RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67922_958318339RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67959_998318339RepeatNote=WD 2-2
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26109_153188346DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+265_48188346DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29109_153188455DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+295_48188455DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+26138_243188346RegionNote=NAKAP95-binding N
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+261_410188346RegionNucleoplasmic
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053+2649_108188346RegionNote=Linker
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+29138_243188455RegionNote=NAKAP95-binding N
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+291_410188455RegionNucleoplasmic
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029+2949_108188455RegionNote=Linker


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FusionGeneSequence for APAF1_TMPO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_574aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKGG
PLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEV
GEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFV

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_534aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTPI
AETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAA

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_574aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKGG
PLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEV
GEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFV

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_534aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTPI
AETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAA

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_585aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_545aa
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1722nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAG
CTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCT
GTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGAC
AAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAA
GAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTG
AAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCT
GTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCAT
AGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACA
CTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGA
CCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGAT
GGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAAT
TTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTG
GGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCT
AGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTT
CCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTT
GTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGA

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1602nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAG
CTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCT
GTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGAC
AAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAA
GAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTG
AAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCT
GTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCAT
AGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACA
CTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATA
GCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATC
ACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAA
AGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCA
GGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAG
TCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTAT

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1722nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAG
CTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCT
GTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGAC
AAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAA
GAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTG
AAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCT
GTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCAT
AGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACA
CTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGA
CCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGAT
GGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAAT
TTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTG
GGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCT
AGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTT
CCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTT
GTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGA

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1602nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAG
CTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCT
GTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGAC
AAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAA
GAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTG
AAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCT
GTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCAT
AGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACA
CTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATA
GCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATC
ACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAA
AGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCA
GGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAG
TCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTAT

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_1755nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_1635nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT


* Fusion transcript sequences (Full-length transcript).
>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_5012nt
ACTTCTACGCGCGCGGGCATGAGCCGTGGCAGGAGTGCGCGGCGGCAGCGGTGGCCGCCCCTTGGGGCTTGGGGTGTGTTTATTTGCATA
AGCGGGCGCGCGCCGTCCGGGCTGGGTGGATCCGGCGGGATTTGACTGCTCCGCTGTCCAGAGGCGGAGAAGAAGAGGTAGCGAGTGGAC
GTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCGAAGACTTGAGGTGCCGCAGCG
GCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGGAAGACCTCCTCCCTTTGTGTC
CAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGTCAGGCTGCGTTGGGTGGACGC
CCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAGGCGCCTGTGAGGCCCGGACCT
GCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTTGCCGTTTCCCTCCACCGGCCT
GGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCATGGTTGACAGCTCAGAGAGAG
AAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACAT
CATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTAT
GCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGC
CCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTG
TGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGG
TGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGA
AGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACG
GTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACA
CCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAG
AGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTT
ATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAA
GCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCA
AGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAG
AAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTAT
AATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTC
AGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCT
TAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATT
AGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGAC
AAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGA
AACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGG
TCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGT
AGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGC
CATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATA
TGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAG
ATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTT
TTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGT
AGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGA
TCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTG
GAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTG
TTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAG
CTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTT
TGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAA
AAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGG
TTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTAC
TTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTT
TTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGC
AATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCT
TCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATG
ATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAA
ATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAA
TAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTA
GCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTG
CAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCT
TTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTT
AGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGA
CCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGA
TGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTT

>In-frame_APAF1_ENST00000551964_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_3341nt
ACTTCTACGCGCGCGGGCATGAGCCGTGGCAGGAGTGCGCGGCGGCAGCGGTGGCCGCCCCTTGGGGCTTGGGGTGTGTTTATTTGCATA
AGCGGGCGCGCGCCGTCCGGGCTGGGTGGATCCGGCGGGATTTGACTGCTCCGCTGTCCAGAGGCGGAGAAGAAGAGGTAGCGAGTGGAC
GTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCGAAGACTTGAGGTGCCGCAGCG
GCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGGAAGACCTCCTCCCTTTGTGTC
CAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGTCAGGCTGCGTTGGGTGGACGC
CCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAGGCGCCTGTGAGGCCCGGACCT
GCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTTGCCGTTTCCCTCCACCGGCCT
GGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCATGGTTGACAGCTCAGAGAGAG
AAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACAT
CATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTAT
GCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGC
CCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTG
TGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGG
TGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGA
AGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACG
GTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACA
CCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAG
AGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTT
ATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAA
GCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTC
AGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGT
CAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACC
ATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTAC
ACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTC
TTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGAT
AAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTT
TCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACA
TTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATA
TATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAAC
TTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGT
GAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAA
ACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTT
TATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACA
GTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGA
ATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAAC
ATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTC
TTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAAT

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4853nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>In-frame_APAF1_ENST00000339433_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_3182nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4820nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGT
ACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATG
GGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCC
AGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGA
TGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCT
CTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGT
TACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGT
TAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAG
AGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAAC
TGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAG
GAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAG
CAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAG
AAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTT
CCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGA
TTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACG
CTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGT
AAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTC
AATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTG
AAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAAT
CTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGT
ATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATT
ATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCA
ACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATA
CTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTA
ACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATT
TTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAG
AAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCC
TATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGG
GCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGG
GCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCA
GAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATAT
TACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGA
GTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCC
TCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCT
GGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTT
AAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGA
CTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTA
CTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCT
TTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGG
GAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTT
TTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAA
TGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACA
TGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAA
GCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATA

>In-frame_APAF1_ENST00000359972_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_3149nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGT
ACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATG
GGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCC
AGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGA
TGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCT
CTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGT
TACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGT
TAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAG
AGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCG
TATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGAC
TGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGC
TGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAAT
TAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAA
ATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCT
GTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGA
CCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACT
TGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACT
TCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCT
TTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAG
TATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATG
TGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAG
TACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAG
TCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAG
CTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTC
ATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATT

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4853nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>In-frame_APAF1_ENST00000333991_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_3182nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4853nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>In-frame_APAF1_ENST00000357310_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_3182nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4320nt
TAGCTCATGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTC
TGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATG
AGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTAC
TACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAA
TAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAA
TTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAG
AAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTC
TGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACC
GTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACA
GTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCT
TAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAG
AATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAA
GAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCAT
TAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTT
CAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCAT
CTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAG
AGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGAC
CAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTC
CCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTT
TTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAA
TGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAA
AATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAAC
TTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCA
TCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACAT
TTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAG
TAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTG
TAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCA
TTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGC
TGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAAT
ATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGT
CTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCG
GTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGT
GAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGG
AGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTC
AAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCA
TTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCG
ATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCT
GACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGT
ACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAA
AATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAA
TGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTG
ATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAG
GTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTC
TTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTA
TAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAA
AAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTT
TATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAA
TAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATGGTTTTCAGATAGCACAAACTGTGATTTCTGGATAACATTTCTTATG

>In-frame_APAF1_ENST00000552268_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_2649nt
TAGCTCATGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTC
TGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATG
AGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTAC
TACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAA
TAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAA
TTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAG
AAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTC
TGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACC
GTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACA
GTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCT
TAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAG
AATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAA
GAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAA
TGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAG
ACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTA
AGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAG
AACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAA
AAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAA
CCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTC
TCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAG
TATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCA
TATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATG
TTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGAT
TTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTT
TGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAG
CCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATC
TTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGA
AATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTT
TAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCT

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4250nt
AGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCA
CATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAA
AATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCA
TGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAG
GAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGG
GAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAA
ACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAA
TATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTG
GGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGT
AGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACA
AGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCC
AGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAA
AGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCG
TATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGAC
TGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGC
TGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAAT
TAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAA
ATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCT
GTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGA
CCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACT
TGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACT
TCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCT
TTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAG
TATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATG
TGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAG
TACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAG
TCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAG
CTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTC
ATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATT
TGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAG
TACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAG
ACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCT
ACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCG
ACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGT
ATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGC
AGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGC
CAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGG
CCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGA
TTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTG
ACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATT
TAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATT
GAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGC
CTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATAC
TGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTA
TGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGG
TCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTA
GACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATGGTTTTCAGATAGCACAAACTGTGATT

>In-frame_APAF1_ENST00000550527_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_2579nt
AGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCA
CATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAA
AATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCA
TGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAG
GAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGG
GAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAA
ACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAA
TATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTG
GGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGT
AGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACA
AGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCC
AGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTAC
TCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCT
GCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAG
AGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGG
GGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGA
TGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTT
GGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCT
TTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGA
TTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAG
TAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCA
TTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTT
AGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAA
AGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTAT
TAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACA
GTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTA
GCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGA
TAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCA

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4281nt
GGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACA
TGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAA
TGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATG
ATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAG
TACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGAT
GGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCC
CAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGG
ATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTC
TCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTG
TTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTG
TTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGA
GAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAA
CTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAA
GGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAA
GCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCA
GAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGT
TCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTG
ATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGAC
GCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAG
TAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTT
CAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATT
GAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAA
TCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTG
TATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAAT
TATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGC
AACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCAT
ACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGT
AACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTAT
TTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTA
GAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCC
CTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAG
GGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTG
GGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGC
AGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATA
TTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGG
AGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGC
CTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGC
TGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTT
TAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTG
ACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTT
ACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATC
TTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTG
GGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACT
TTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAA
ATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAAC
ATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAA
AGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAAT

>In-frame_APAF1_ENST00000547045_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_2610nt
GGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACA
TGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAA
TGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATG
ATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAG
TACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGAT
GGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCC
CAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGG
ATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTC
TCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTG
TTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTG
TTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGA
GAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTC
GTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGA
CTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAG
CTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAA
TTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTA
AATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGC
TGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTG
ACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACAC
TTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGAC
TTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGC
TTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTA
GTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATAT
GTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAA
GTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAA
GTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTA
GCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGT
CATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCAT
TTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAA

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000556029_chr12_98931253_+_4276nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT
CCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATA
ACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAA
GCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTT
TTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTT
GGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTC
TCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAA
AGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCA
CTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACAT
ACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTT
ATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAAT
TGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATA
TTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGG
GTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGT
GATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGA
TTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACA
TCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCT
CACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGG
CAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGA
TTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGC
TGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCA
TTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAA
AAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCA
TACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAA
CTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCT
TTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTG
GGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTA
GTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCAT
TTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATG

>In-frame_APAF1_ENST00000549007_chr12_99056584_+_TMPO_ENST00000343315_chr12_98931253_+_2605nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT
AGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTT
GACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCAT
TAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTAT
TTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATA
ATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAA
ACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACA
GCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCT
ATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGT
ACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCC
AGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGA


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FusionGenePPI for APAF1_TMPO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
APAF1APIP, CASP9, NLRP1, HSPA4, HSP90AA1, CASP4, CASP8, BCL2L1, CYCS, AVEN, TRIAP1, ELAVL1, PPP1CA, XIAP, TOP1, SHMT2, ENDOV, HSP90B1, DEF8, OMD, WDFY3, LINC01587, KIAA1683, LGALS7, AARSD1, LYPD4, CRYBA4TMPORB1, LMNA, AKAP8L, BANF1, LMNB1, LMNB2, CLN3, FYCO1, HDAC3, RNF185, MYC, SMN1, SMARCAD1, RAD21, HDGF, OIP5, ARRB1, ARRB2, XRCC5, PCGF2, USP7, FBXO6, HP1BP3, MRE11A, ILF3, PFKP, CIRBP, PAXIP1, TP53BP1, SMURF1, YWHAE, FMNL1, CSNK2A1, CD81, HDAC9, HDAC11, RPA3, RPA2, RPA1, SPRTN, CUL7, OBSL1, CCDC8, EED, SUMO2, ABCE1, LGALS3, UNK, NTRK1, LARS, MESDC2, SCARNA22, NUP133, NUP160, NUP35, SRPK2, CLK1, TCTN2, TCTN3, TMEM216, HIST1H3E, ATRX, BST2, CHD1, STOM, HSPG2, LIG3, PHB, RRBP1, SDC2, SUPT6H, XRCC3, ZWINT, AP4S1, TMEM63B, TUBG1, UBTF, VARS, MLLT10, HIST1H2BC, HIRIP3, ATP6V0D1, NOLC1, KAT7, RPL35, PHB2, EXOSC8, BRD1, NUSAP1, PHIP, JADE1, PRKCDBP, SGMS2, CRY2, NF2, SNW1, CDC5L, U2AF2, AIRE, CDH1, EYA1, MTMR14, DLD, DLST, PDHA1, FOXA1, SRC, ABL1, YAP1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for APAF1_TMPO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for APAF1_TMPO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAPAF1C0041696Unipolar Depression2PSYGENET
HgeneAPAF1C0376634Craniofacial Abnormalities2CTD_human
HgeneAPAF1C1269683Major Depressive Disorder2PSYGENET
HgeneAPAF1C0007134Renal Cell Carcinoma1CTD_human
HgeneAPAF1C0007138Carcinoma, Transitional Cell1CTD_human
HgeneAPAF1C0015393Eye Abnormalities1CTD_human
HgeneAPAF1C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneAPAF1C0035305Retinal Detachment1CTD_human
HgeneAPAF1C0037268Skin Abnormalities1CTD_human
TgeneTMPOC0003873Rheumatoid Arthritis1CTD_human
TgeneTMPOC0007193Cardiomyopathy, Dilated1CTD_human;HPO
TgeneTMPOC0151744Myocardial Ischemia1CTD_human