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Fusion gene ID: 20817 |
FusionGeneSummary for MAP2K5_IQCH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAP2K5_IQCH | Fusion gene ID: 20817 | Hgene | Tgene | Gene symbol | MAP2K5 | IQCH | Gene ID | 5607 | 128153 |
| Gene name | mitogen-activated protein kinase kinase 5 | spermatogenesis associated 17 | |
| Synonyms | HsT17454|MAPKK5|MEK5|PRKMK5 | IQCH|MSRG-11|MSRG11 | |
| Cytomap | 15q23 | 1q41 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dual specificity mitogen-activated protein kinase kinase 5MAP kinase kinase 5MAP kinase kinase MEK5bMAPK/ERK kinase 5MAPKK 5MEK 5 | spermatogenesis-associated protein 17IQ motif containing Hspermatogenesis-related protein 11 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q13163 | Q86VS3 | |
| Ensembl transtripts involved in fusion gene | ENST00000178640, ENST00000560591, ENST00000395476, ENST00000354498, ENST00000340972, | ENST00000358767, ENST00000546225, ENST00000335894, ENST00000360277, ENST00000512104, ENST00000560790, | |
| Fusion gene scores | * DoF score | 6 X 6 X 7=252 | 4 X 4 X 4=64 |
| # samples | 7 | 5 | |
| ** MAII score | log2(7/252*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAP2K5 [Title/Abstract] AND IQCH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | CESC | TCGA-C5-A7X3-01A | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| TCGA | RV | PRAD | TCGA-EJ-A46G-01A | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000178640 | ENST00000358767 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000178640 | ENST00000546225 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000178640 | ENST00000335894 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000178640 | ENST00000360277 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000178640 | ENST00000512104 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000178640 | ENST00000560790 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000358767 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000546225 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000335894 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000360277 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000512104 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 3UTR-intron | ENST00000560591 | ENST00000560790 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000358767 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000546225 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000335894 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000360277 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000512104 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000395476 | ENST00000560790 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000358767 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000546225 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000335894 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000360277 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000512104 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| 5CDS-intron | ENST00000354498 | ENST00000560790 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000358767 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000546225 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000335894 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000360277 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000512104 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| intron-intron | ENST00000340972 | ENST00000560790 | MAP2K5 | chr15 | 67885312 | + | IQCH | chr15 | 67782341 | + |
| In-frame | ENST00000178640 | ENST00000358767 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000178640 | ENST00000546225 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000178640 | ENST00000335894 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000178640 | ENST00000360277 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000178640 | ENST00000512104 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000178640 | ENST00000560790 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000560591 | ENST00000358767 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000560591 | ENST00000546225 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000560591 | ENST00000335894 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000560591 | ENST00000360277 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-intron | ENST00000560591 | ENST00000512104 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-intron | ENST00000560591 | ENST00000560790 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000395476 | ENST00000358767 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000395476 | ENST00000546225 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000395476 | ENST00000335894 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-3CDS | ENST00000395476 | ENST00000360277 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-intron | ENST00000395476 | ENST00000512104 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| intron-intron | ENST00000395476 | ENST00000560790 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000354498 | ENST00000358767 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000354498 | ENST00000546225 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000354498 | ENST00000335894 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000354498 | ENST00000360277 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000354498 | ENST00000512104 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000354498 | ENST00000560790 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000340972 | ENST00000358767 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000340972 | ENST00000546225 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000340972 | ENST00000335894 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| In-frame | ENST00000340972 | ENST00000360277 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000340972 | ENST00000512104 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
| 5CDS-intron | ENST00000340972 | ENST00000560790 | MAP2K5 | chr15 | 68020283 | + | IQCH | chr15 | 67757465 | + |
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FusionProtFeatures for MAP2K5_IQCH |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAP2K5 | IQCH |
| Acts as a scaffold for the formation of a ternaryMAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of thispathway appears to play a critical role in protecting cells fromstress-induced apoptosis, neuronal survival and cardiacdevelopment and angiogenesis. {ECO:0000269|PubMed:7759517,ECO:0000269|PubMed:9384584}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 18_109 | 358 | 449 | Domain | PB1 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 18_109 | 322 | 413 | Domain | PB1 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 172_180 | 358 | 449 | Nucleotide binding | ATP |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 172_180 | 322 | 413 | Nucleotide binding | ATP |
| Tgene | >IQCH | chr15:68020283 | chr15:67757465 | ENST00000512104 | + | 0 | 6 | 369_398 | -33 | 169 | Domain | IQ |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 166_409 | 358 | 449 | Domain | Protein kinase |
| Hgene | >MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 166_409 | 322 | 413 | Domain | Protein kinase |
| Hgene | >MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 166_409 | -2 | 439 | Domain | Protein kinase |
| Hgene | >MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 18_109 | -2 | 439 | Domain | PB1 |
| Hgene | >MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 172_180 | -2 | 439 | Nucleotide binding | ATP |
| Tgene | IQCH | chr15:68020283 | chr15:67757465 | ENST00000335894 | + | 15 | 21 | 369_398 | 835 | 1028 | Domain | IQ |
| Tgene | IQCH | chr15:68020283 | chr15:67757465 | ENST00000360277 | + | 7 | 12 | 369_398 | 496 | 1009 | Domain | IQ |
| Tgene | IQCH | chr15:68020283 | chr15:67757465 | ENST00000546225 | + | 14 | 20 | 369_398 | 492 | 685 | Domain | IQ |
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FusionGeneSequence for MAP2K5_IQCH |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_484aa MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVM EQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKG LTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVW ATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHG >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_551aa MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVM EQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKG LTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVW ATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHG IGYDVEERQGTVFILYEHLKRHKLGMLTIGEDLQGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSK >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_551aa MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVM EQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKG LTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVW ATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHG IGYDVEERQGTVFILYEHLKRHKLGMLTIGEDLQGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSK >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_484aa MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVM EQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKG LTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVW ATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHG >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_448aa MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRA GPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVST QLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVP >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_515aa MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRA GPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVST QLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVP RFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVEERQGTVFILYEHLKRHKLGMLTIGEDLQGV >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_515aa MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRA GPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVST QLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVP RFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVEERQGTVFILYEHLKRHKLGMLTIGEDLQGV >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_448aa MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRA GPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEIL YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVST QLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVP >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_294aa MEDFEVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKIL HRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSD QLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVENNRR >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_361aa MEDFEVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKIL HRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSD QLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVEERQG TVFILYEHLKRHKLGMLTIGEDLQGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSKDDKNLSKPKK >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_361aa MEDFEVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKIL HRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSD QLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVEERQG TVFILYEHLKRHKLGMLTIGEDLQGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSKDDKNLSKPKK >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_294aa MEDFEVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKIL HRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQVWATGLNLAYSD QLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDVENNRR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_1452nt ATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGAC TGGACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTT GAATATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATG GAACAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTG AAGGTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCT GAACTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTC TACAAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATG TCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGT ACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGC CTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGT GATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGG GAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGG GCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTG AGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGT CGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGC ATTGGCTATGATGTTGAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAAT >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_1653nt ATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGAC TGGACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTT GAATATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATG GAACAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTG AAGGTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCT GAACTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTC TACAAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATG TCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGT ACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGC CTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGT GATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGG GAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGG GCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTG AGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGT CGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGC ATTGGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGC GAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACC AATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAA >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_1653nt ATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGAC TGGACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTT GAATATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATG GAACAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTG AAGGTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCT GAACTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTC TACAAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATG TCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGT ACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGC CTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGT GATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGG GAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGG GCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTG AGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGT CGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGC ATTGGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGC GAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACC AATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAA >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_1452nt ATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGAC TGGACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTT GAATATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATG GAACAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTG AAGGTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCT GAACTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTC TACAAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATG TCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGT ACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGC CTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGT GATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGG GAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGG GCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTG AGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGT CGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGC ATTGGCTATGATGTTGAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAAT >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_1344nt ATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAAGAT GGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAATGGA CAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGGGCC GGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATACTA GCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTC CCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTT TATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGG GGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGT TTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACT CAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCAT TCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTC GCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCC CGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACC ACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAG >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_1545nt ATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAAGAT GGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAATGGA CAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGGGCC GGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATACTA GCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTC CCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTT TATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGG GGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGT TTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACT CAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCAT TCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTC GCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCC CGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACC ACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAG GAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTC CTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATT GCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCT >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_1545nt ATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAAGAT GGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAATGGA CAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGGGCC GGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATACTA GCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTC CCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTT TATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGG GGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGT TTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACT CAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCAT TCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTC GCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCC CGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACC ACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAG GAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTC CTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATT GCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCT >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_1344nt ATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAAGAT GGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAATGGA CAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGGGCC GGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATACTA GCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTC CCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTT TATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGG GGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGT TTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACT CAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCAT TCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTC GCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCC CGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACC ACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAG >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_882nt ATGGAGGACTTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGAT TCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGAT GTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTA CATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAAT TCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGG AGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGAC CAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCA AAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGA CACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGAACAATCGGCGA >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_1083nt ATGGAGGACTTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGAT TCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGAT GTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTA CATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAAT TCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGG AGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGAC CAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCA AAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGA CACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGGAAAGGCAAGGA ACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTT GCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAA ACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAA >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_1083nt ATGGAGGACTTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGAT TCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGAT GTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTA CATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAAT TCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGG AGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGAC CAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCA AAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGA CACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGGAAAGGCAAGGA ACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTT GCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAA ACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAA >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_882nt ATGGAGGACTTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGAT TCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGAT GTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTA CATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAAT TCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGG AGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGAC CAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCA AAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGA CACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGAACAATCGGCGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_3275nt CTCCTCCTCCTCTCGCCGCTACCGCCGTCGCCGCCGCCGCAGCCGCCGCCAGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCG CGCCGCGCCCTGTGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTCCGTGGTGTGGCGGCCCTGGGGCTCT TTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCGAGGACCCTCTCCTAGTCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCC CAAACCGAGTCCTTGCCCTGCTGCCTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCGTTCGCTCAACTCCAGAACCTTCCGA CCTCCGCTAGTTCCTGCGGGCCTTTGCCCGCTTCCCGGTGCACCCTCCCCGGGAGACACCTCAGACCCCCGACAGCCTGGGCAGGCTCGG TGCCTGCGGGTGCGTTCCTGATCACCCCTCCCCTCTTCCCTCCCCCTCATCCTCCATTCCCTTGTTTTCACCCTCTGTCCTCTGCCCGTC ACTCCCCTTGTCACCTCTTGGAGCCCCCTCCTAACCAGCGGCCAGTGGGTTTCCCATACCCCAGGATGTGAGCCTCTTTAACCTGTAATG CTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGACTGG ACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAA TATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAA CAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAG GTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAA CTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTAC AAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCT GAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACA GAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTT ACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGAT TTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAG CAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCA ACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGC ACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGC TATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATT GGCTATGATGTTGAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATC AGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAG ATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCC CAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAG AACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCAT TTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCAC CTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATC GATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATAT TGAAATTATATTTATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTT TTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTG TAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACA TTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATT TCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTA TAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAA >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_3337nt CTCCTCCTCCTCTCGCCGCTACCGCCGTCGCCGCCGCCGCAGCCGCCGCCAGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCG CGCCGCGCCCTGTGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTCCGTGGTGTGGCGGCCCTGGGGCTCT TTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCGAGGACCCTCTCCTAGTCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCC CAAACCGAGTCCTTGCCCTGCTGCCTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCGTTCGCTCAACTCCAGAACCTTCCGA CCTCCGCTAGTTCCTGCGGGCCTTTGCCCGCTTCCCGGTGCACCCTCCCCGGGAGACACCTCAGACCCCCGACAGCCTGGGCAGGCTCGG TGCCTGCGGGTGCGTTCCTGATCACCCCTCCCCTCTTCCCTCCCCCTCATCCTCCATTCCCTTGTTTTCACCCTCTGTCCTCTGCCCGTC ACTCCCCTTGTCACCTCTTGGAGCCCCCTCCTAACCAGCGGCCAGTGGGTTTCCCATACCCCAGGATGTGAGCCTCTTTAACCTGTAATG CTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGACTGG ACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAA TATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAA CAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAG GTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAA CTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTAC AAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCT GAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACA GAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTT ACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGAT TTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAG CAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCA ACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGC ACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGC TATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATT GGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAG GATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAAT TTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGAT GATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTT TTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTA AAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCT TCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCA GGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAA AGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAG TGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTA GTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAAC ATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGT TAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGT GAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAG GAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAAGAGTTTCTGTAATAAAATTAACATTTGT >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_3338nt CTCCTCCTCCTCTCGCCGCTACCGCCGTCGCCGCCGCCGCAGCCGCCGCCAGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCG CGCCGCGCCCTGTGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTCCGTGGTGTGGCGGCCCTGGGGCTCT TTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCGAGGACCCTCTCCTAGTCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCC CAAACCGAGTCCTTGCCCTGCTGCCTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCGTTCGCTCAACTCCAGAACCTTCCGA CCTCCGCTAGTTCCTGCGGGCCTTTGCCCGCTTCCCGGTGCACCCTCCCCGGGAGACACCTCAGACCCCCGACAGCCTGGGCAGGCTCGG TGCCTGCGGGTGCGTTCCTGATCACCCCTCCCCTCTTCCCTCCCCCTCATCCTCCATTCCCTTGTTTTCACCCTCTGTCCTCTGCCCGTC ACTCCCCTTGTCACCTCTTGGAGCCCCCTCCTAACCAGCGGCCAGTGGGTTTCCCATACCCCAGGATGTGAGCCTCTTTAACCTGTAATG CTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGACTGG ACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAA TATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAA CAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAG GTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAA CTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTAC AAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCT GAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACA GAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTT ACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGAT TTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAG CAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCA ACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGC ACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGC TATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATT GGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAG GATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAAT TTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGAT GATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTT TTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTA AAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCT TCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCA GGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAA AGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAG TGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTA GTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAAC ATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGT TAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGT GAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAG GAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAAGAGTTTCTGTAATAAAATTAACATTTGT >In-frame_MAP2K5_ENST00000178640_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_3275nt CTCCTCCTCCTCTCGCCGCTACCGCCGTCGCCGCCGCCGCAGCCGCCGCCAGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCG CGCCGCGCCCTGTGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTCCGTGGTGTGGCGGCCCTGGGGCTCT TTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCGAGGACCCTCTCCTAGTCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCC CAAACCGAGTCCTTGCCCTGCTGCCTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCGTTCGCTCAACTCCAGAACCTTCCGA CCTCCGCTAGTTCCTGCGGGCCTTTGCCCGCTTCCCGGTGCACCCTCCCCGGGAGACACCTCAGACCCCCGACAGCCTGGGCAGGCTCGG TGCCTGCGGGTGCGTTCCTGATCACCCCTCCCCTCTTCCCTCCCCCTCATCCTCCATTCCCTTGTTTTCACCCTCTGTCCTCTGCCCGTC ACTCCCCTTGTCACCTCTTGGAGCCCCCTCCTAACCAGCGGCCAGTGGGTTTCCCATACCCCAGGATGTGAGCCTCTTTAACCTGTAATG CTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTGGTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGACTGG ACAGTGCACTCCGGGCCGCAGTTACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAA TATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAA CAGCAAGTAAATGGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAG GTGAATACTCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAA CTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTAC AAAGCATATCATGTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCT GAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACA GAATTCATGGATGGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTT ACTTATTTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGAT TTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAG CAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCA ACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGC ACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGC TATGCAGTGATGACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATT GGCTATGATGTTGAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATC AGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAG ATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCC CAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAG AACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCAT TTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCAC CTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATC GATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATAT TGAAATTATATTTATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTT TTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTG TAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACA TTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATT TCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTA TAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAA >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_2723nt GAAGTTGCAGCCACTCTGCTAAGTGCCCTGCTTGGAAAGGCTGTGGGCTCCCTGCTGAGAAATACTGCGAGCGGCTTTGTCAGCCGGCTG CCTGGTGCCAGTTCTGCTGCAGCCTGGGAGGGACACTGTGGCAGAGCTCCTGGAGAGAAATGAGGTTTGCAGGCCATTGGAGTTGGACTG GACATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAA GATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAAT GGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGG GCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATA CTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCAT GTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATT CTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGAT GGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGG AGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGC ACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATT CATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAAC CTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTG CCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATG ACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTT GAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATAT GCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGA GCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATA AAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAA TGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTG AACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTAC TTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCAT TTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATT TATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAG GATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTC TGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTT TAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTG AGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTT AGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAAGAGTTTCTGTAA >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_2785nt GAAGTTGCAGCCACTCTGCTAAGTGCCCTGCTTGGAAAGGCTGTGGGCTCCCTGCTGAGAAATACTGCGAGCGGCTTTGTCAGCCGGCTG CCTGGTGCCAGTTCTGCTGCAGCCTGGGAGGGACACTGTGGCAGAGCTCCTGGAGAGAAATGAGGTTTGCAGGCCATTGGAGTTGGACTG GACATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAA GATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAAT GGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGG GCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATA CTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCAT GTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATT CTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGAT GGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGG AGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGC ACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATT CATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAAC CTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTG CCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATG ACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTT GAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGG GTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACC ATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTC TCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAA ATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTA TTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAG AAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGC TTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAAT TGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATCATTC ATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGC ATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTC TAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGT AGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCA AATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTT >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_2786nt GAAGTTGCAGCCACTCTGCTAAGTGCCCTGCTTGGAAAGGCTGTGGGCTCCCTGCTGAGAAATACTGCGAGCGGCTTTGTCAGCCGGCTG CCTGGTGCCAGTTCTGCTGCAGCCTGGGAGGGACACTGTGGCAGAGCTCCTGGAGAGAAATGAGGTTTGCAGGCCATTGGAGTTGGACTG GACATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAA GATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAAT GGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGG GCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATA CTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCAT GTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATT CTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGAT GGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGG AGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGC ACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATT CATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAAC CTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTG CCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATG ACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTT GAGGAAAGGCAAGGAACTGTTTTTATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGG GTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACC ATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTC TCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAA ATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTA TTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAG AAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGC TTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAAT TGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATCATTC ATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGC ATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTC TAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGT AGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCA AATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTT >In-frame_MAP2K5_ENST00000354498_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_2723nt GAAGTTGCAGCCACTCTGCTAAGTGCCCTGCTTGGAAAGGCTGTGGGCTCCCTGCTGAGAAATACTGCGAGCGGCTTTGTCAGCCGGCTG CCTGGTGCCAGTTCTGCTGCAGCCTGGGAGGGACACTGTGGCAGAGCTCCTGGAGAGAAATGAGGTTTGCAGGCCATTGGAGTTGGACTG GACATGATGGAGGGTCACTTTCCCCAGAGCGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATTTGAATATGAAGATGAA GATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATGCTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAAT GGACAGTTAATAGAGCCTCTGCAGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATACTCGG GCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTAAAGAAGTCTTCTGCTGAACTGAAAAAAATA CTAGCCAATGGCCAGATGAATGAACAAGACATACGATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCAT GTCCCGAGTGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATT CTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGAT GGGGGATCTTTGGATGTATATAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGG AGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGC ACTCAGCTGGTGAATTCTATAGCCAAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATT CATTCTGATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAAC CTCGCATATAGTGACCAGCTGGCCCTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTG CCCCGCTTTGTTCCAAAGGAAAGGAAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATG ACCACCCAGCTAAGACACAGCAATCTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTT GAGAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATAT GCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGA GCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATA AAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAA TGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTG AACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTAC TTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCAT TTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATT TATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAG GATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTC TGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTT TAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTG AGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTT AGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTGTTAACTGTGATTCAGCCACAGGCTAAGAGTTTCTGTAA >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000358767_chr15_67757465_+_2429nt AAACTGAATCACCTGCAGGGTCTGACGCCTGCATGGAATGATGAGGGAAATTTAATTTTCCAAGCAAAGTGTGAAGTGTGTGCCACTCCA GCAAATAAACGAAGTCATCCATGACAGCTTGTGATGAATTGCCGTATTTATACTGTATATTTTAATAGCCTCACACTAATTTAAATTGAG CACAGAGTAAATTATAATTCAGTCACTTGACTGCTTATATTTAACTTGACAACTCATCCTTATTTGTCCTGGAGGTGTAGTGGAGAGCAG TGGAAATGCACCAAGGAGATGAGGGATGCATGCTCAAGGCAGAATGTACATATTGAGGGCCAGAGCTAGAGATGAATTTTGATGGAGGAC TTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATAT ATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGG AAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGAC GTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCC AAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGA ATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCC CTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGG AAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAAT CTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGAACAATCGGCGAGGATCTCCA GGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGAC CACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAA CCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTT AGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTG TTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAAC TCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATG TAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAA GAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATC ATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCA AAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTAT TCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTG TAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAA AGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGA >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000546225_chr15_67757465_+_2491nt AAACTGAATCACCTGCAGGGTCTGACGCCTGCATGGAATGATGAGGGAAATTTAATTTTCCAAGCAAAGTGTGAAGTGTGTGCCACTCCA GCAAATAAACGAAGTCATCCATGACAGCTTGTGATGAATTGCCGTATTTATACTGTATATTTTAATAGCCTCACACTAATTTAAATTGAG CACAGAGTAAATTATAATTCAGTCACTTGACTGCTTATATTTAACTTGACAACTCATCCTTATTTGTCCTGGAGGTGTAGTGGAGAGCAG TGGAAATGCACCAAGGAGATGAGGGATGCATGCTCAAGGCAGAATGTACATATTGAGGGCCAGAGCTAGAGATGAATTTTGATGGAGGAC TTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATAT ATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGG AAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGAC GTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCC AAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGA ATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCC CTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGG AAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAAT CTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTT ATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCAT CTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTA AGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGG AATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTT GCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATT AAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAG AAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAG TTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGC CTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCC ACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGT ATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGT AGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCAT TCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATT GTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTG >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000335894_chr15_67757465_+_2492nt AAACTGAATCACCTGCAGGGTCTGACGCCTGCATGGAATGATGAGGGAAATTTAATTTTCCAAGCAAAGTGTGAAGTGTGTGCCACTCCA GCAAATAAACGAAGTCATCCATGACAGCTTGTGATGAATTGCCGTATTTATACTGTATATTTTAATAGCCTCACACTAATTTAAATTGAG CACAGAGTAAATTATAATTCAGTCACTTGACTGCTTATATTTAACTTGACAACTCATCCTTATTTGTCCTGGAGGTGTAGTGGAGAGCAG TGGAAATGCACCAAGGAGATGAGGGATGCATGCTCAAGGCAGAATGTACATATTGAGGGCCAGAGCTAGAGATGAATTTTGATGGAGGAC TTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATAT ATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGG AAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGAC GTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCC AAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGA ATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCC CTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGG AAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAAT CTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGGAAAGGCAAGGAACTGTTTTT ATATTATATGAGCACCTGAAGAGACACAAGTTGGGAATGTTAACAATCGGCGAGGATCTCCAGGGGGTCCTCATGACCTTTGCTCGCCAT CTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGACCACCATTGCTGATATTGAAACTATTCTA AGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAACCTCTCTAAACCCAAGAAATGATCCTGG AATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTTAGAAATAAAAGCCAGGGGAAATTGGTTT GCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTGTTTATTAAGTGATCTTATTTTATTTATT AAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAACTCAGAAAAAAGTAATCTGATAAAAGAAG AAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATGTAGCTTTTATTTTTTATGTTTTATAAAG TTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAAGAATTGCTATTTGTCAAAACACAAATGC CTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATCATTCATCGTGTTTTTGTTATACCAAGCC ACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCAAAGCATCAGAATGTATCTAGGTGGCAGT ATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTATTCTCTAGTTCTCCATTTAATACAGCAGT AGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTGTAGTAGTGCTGACTCTAACTTTCAGCAT TCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAAAGCAAATTACAACACCAAAACCATTATT GTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGATTTTTACCTGTGGAATTTCAATAATTTG >In-frame_MAP2K5_ENST00000340972_chr15_68020283_+_IQCH_ENST00000360277_chr15_67757465_+_2429nt AAACTGAATCACCTGCAGGGTCTGACGCCTGCATGGAATGATGAGGGAAATTTAATTTTCCAAGCAAAGTGTGAAGTGTGTGCCACTCCA GCAAATAAACGAAGTCATCCATGACAGCTTGTGATGAATTGCCGTATTTATACTGTATATTTTAATAGCCTCACACTAATTTAAATTGAG CACAGAGTAAATTATAATTCAGTCACTTGACTGCTTATATTTAACTTGACAACTCATCCTTATTTGTCCTGGAGGTGTAGTGGAGAGCAG TGGAAATGCACCAAGGAGATGAGGGATGCATGCTCAAGGCAGAATGTACATATTGAGGGCCAGAGCTAGAGATGAATTTTGATGGAGGAC TTTGAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATTATGTCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATAT ATCATTGGATTTTATGGAGCATTTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATATAGG AAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTATTTGTGGAGTTTAAAGATTTTACATAGAGAC GTGAAGCCCTCCAATATGCTAGTAAACACAAGAGGACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCC AAGACGTATGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCTGATGTCTGGAGCTTAGGA ATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGGTGTGGGCAACCGGCCTTAACCTCGCATATAGTGACCAGCTGGCC CTGACTCAACTCACCTTATACCTGACAAACGGCCATCTGGATTGCAGTTTGAGCACCCTGGAAGTGCCCCGCTTTGTTCCAAAGGAAAGG AAGAAAACCAAATGCATGAGTGCGCTGTCAATGCCGATGCTGGCAACCAGTCGCTATGCAGTGATGACCACCCAGCTAAGACACAGCAAT CTCTCACTGGTTTTCCACTATGTTTTTCTCCAGATCTGTAGGGCCCATGGCATTGGCTATGATGTTGAGAACAATCGGCGAGGATCTCCA GGGGGTCCTCATGACCTTTGCTCGCCATCTCTTCATCATCCATCAAGAAATATCAGCACCTAATATGCAAGGCGAGACCAATTTTAAGAC CACCATTGCTGATATTGAAACTATTCTAAGAGTAACAAAGGAAAACAAAATGAGATTTGAAGAGGAGCAACAGTCCAAAGATGATAAAAA CCTCTCTAAACCCAAGAAATGATCCTGGAATACAGTACATAACAATTTGGATCCCAGTCTGGAATAAAAAGGGCAATTTTTTTTTCTGTT AGAAATAAAAGCCAGGGGAAATTGGTTTGCTTTGTGTGCTAGGAGGTGAATCAGAACAGATTATAATGAAATGCTCTTTTTAAAACATTG TTTATTAAGTGATCTTATTTTATTTATTAAACCAAAACTTATTTGTGTTTTCATTTGAGAGTGTTGAACAATCCCTTCTTCTTCTCAAAC TCAGAAAAAAGTAATCTGATAAAAGAAGAAAGTTAAAAGTCTTACTGATATCACCTCCGCATTTACTTCCTCATAGGCCTCAGGATTATG TAGCTTTTATTTTTTATGTTTTATAAAGTTTTCTCCTATTTCTAATAGTCCATCGATCTTCTGCATTTATAGGTTTGAATAAAGGCTTAA GAATTGCTATTTGTCAAAACACAAATGCCTTTTTTTCAAAGCTTCAAATTATATTGAAATTATATTTATATGAATTTTTAAGTGACTATC ATTCATCGTGTTTTTGTTATACCAAGCCACTATTGTCTGCTATTGTTGCCATTTTTCAAAAAGTAGGATAAGCCAGCATCTAGTTAACCA AAGCATCAGAATGTATCTAGGTGGCAGTATCTGCTCTTAGTTTAAGATGGAGTGTAGCTCGAGCTCTGTAGCTTGAATAAACATTTGTAT TCTCTAGTTCTCCATTTAATACAGCAGTAGGATTTTTTCAAGTTTAGTTCAACATTATACTACCTTTAAAAAGGCAGACTGTTAAGATTG TAGTAGTGCTGACTCTAACTTTCAGCATTCACTTCATAATTGTCCAAAAATATTTCCACATCAGTGAGCTTTACTGAAGGGTGAAATAAA AGCAAATTACAACACCAAAACCATTATTGTTTTAAAGAATGACCTTTATGTCTATAAAAATATTTTAGTGTATTGGGGAAAGGAATAGGA |
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FusionGenePPI for MAP2K5_IQCH |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MAP2K5 | MAP3K3, MAP3K2, PRKCZ, MAPK7, MAP2K5, YWHAZ, CDC42BPB, ENO1, SQSTM1, ASRGL1, STAMBP, PRKCI, PARD6A, HSP90AA1, GCH1, XRCC6, ESRRA, RPL28, NXF1, LNX2, TRAF7, C10orf88, CDC37 | IQCH | APP, CBX6 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 64_68 | 358 | 449 | MAP3K2/MAP3K3 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 64_68 | 322 | 413 | MAP3K2/MAP3K3 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 117_131 | 358 | 449 | MAPK7 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000178640 | + | 17 | 22 | 18_25 | 358 | 449 | MAPK7 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 117_131 | 322 | 413 | MAPK7 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000354498 | + | 17 | 22 | 18_25 | 322 | 413 | MAPK7 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 64_68 | -2 | 439 | MAP3K2/MAP3K3 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 117_131 | -2 | 439 | MAPK7 |
| Hgene | MAP2K5 | chr15:68020283 | chr15:67757465 | ENST00000395476 | + | 1 | 21 | 18_25 | -2 | 439 | MAPK7 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MAP2K5_IQCH |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MAP2K5_IQCH |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MAP2K5 | C0005910 | Body Weight | 1 | CTD_human |
| Hgene | MAP2K5 | C0011581 | Depressive disorder | 1 | PSYGENET |
| Hgene | MAP2K5 | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
| Tgene | IQCH | C0025202 | melanoma | 1 | CTD_human |
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