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Fusion gene ID: 2081 |
FusionGeneSummary for AP3B1_DCTN4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AP3B1_DCTN4 | Fusion gene ID: 2081 | Hgene | Tgene | Gene symbol | AP3B1 | DCTN4 | Gene ID | 8546 | 51164 |
| Gene name | adaptor related protein complex 3 subunit beta 1 | dynactin subunit 4 | |
| Synonyms | ADTB3|ADTB3A|HPS|HPS2|PE | DYN4|P62 | |
| Cytomap | 5q14.1 | 5q33.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AP-3 complex subunit beta-1AP-3 complex beta-3A subunitadaptor protein complex AP-3 subunit beta-1adaptor related protein complex 3 beta 1 subunitbeta-3A-adaptinclathrin assembly protein complex 3 beta-1 large chain | dynactin subunit 4dynactin 4 (p62)dynactin p62 subunitdynactin subunit p62 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O00203 | Q9UJW0 | |
| Ensembl transtripts involved in fusion gene | ENST00000255194, ENST00000519295, ENST00000523204, | ENST00000447998, ENST00000424236, ENST00000446090, ENST00000521093, | |
| Fusion gene scores | * DoF score | 6 X 7 X 5=210 | 2 X 3 X 2=12 |
| # samples | 7 | 3 | |
| ** MAII score | log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: AP3B1 [Title/Abstract] AND DCTN4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KIRC | TCGA-BP-4986-01A | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000255194 | ENST00000447998 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000255194 | ENST00000424236 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000255194 | ENST00000446090 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000255194 | ENST00000521093 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| In-frame | ENST00000519295 | ENST00000447998 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000519295 | ENST00000424236 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000519295 | ENST00000446090 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| 5CDS-5UTR | ENST00000519295 | ENST00000521093 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| intron-3CDS | ENST00000523204 | ENST00000447998 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| intron-5UTR | ENST00000523204 | ENST00000424236 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| intron-5UTR | ENST00000523204 | ENST00000446090 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
| intron-5UTR | ENST00000523204 | ENST00000521093 | AP3B1 | chr5 | 77423854 | - | DCTN4 | chr5 | 150136049 | - |
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FusionProtFeatures for AP3B1_DCTN4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AP3B1 | DCTN4 |
| Subunit of non-clathrin- and clathrin-associated adaptorprotein complex 3 (AP-3) that plays a role in protein sorting inthe late-Golgi/trans-Golgi network (TGN) and/or endosomes. The APcomplexes mediate both the recruitment of clathrin to membranesand the recognition of sorting signals within the cytosolic tailsof transmembrane cargo molecules. AP-3 appears to be involved inthe sorting of a subset of transmembrane proteins targeted tolysosomes and lysosome-related organelles. In concert with theBLOC-1 complex, AP-3 is required to target cargos into vesiclesassembled at cell bodies for delivery into neurites and nerveterminals. | Could have a dual role in dynein targeting and inACTR1A/Arp1 subunit of dynactin pointed-end capping. Could beinvolved in ACTR1A pointed-end binding and in additional roles inlinking dynein and dynactin to the cortical cytoskeleton. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >DCTN4 | chr5:77423854 | chr5:150136049 | ENST00000424236 | - | 0 | 13 | 152_172 | -12 | 404 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >DCTN4 | chr5:77423854 | chr5:150136049 | ENST00000446090 | - | 0 | 14 | 152_172 | 45 | 468 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >DCTN4 | chr5:77423854 | chr5:150136049 | ENST00000447998 | - | 0 | 13 | 152_172 | 45 | 461 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >AP3B1 | chr5:77423854 | chr5:150136049 | ENST00000255194 | - | 17 | 27 | 677_802 | 656 | 1095 | Compositional bias | Note=Glu/Ser-rich |
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FusionGeneSequence for AP3B1_DCTN4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AP3B1_ENST00000255194_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_1072aa MSSNSFPYNEQSGGGEATELGQEATSTISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASK NIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSL DPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEGDELEDNG KNFYESDDDQKEKTDKKKKPYTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGIISKSLVRLLRSNREVQYIVLQNIATM SIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATIQTIGRCATNILEVTDTCLNGLVCLL SNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLG AKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNVKSGALSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKA TGYLELSNWPEVAPDPSVRNVEVIELVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYL ACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASIST LAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEF NPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDEL >In-frame_AP3B1_ENST00000519295_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_1023aa MLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVL SSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKL CNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEGDELEDNGKNFYESDDDQKEKTDKKKKPYTMDPDHRLLIRNTKPLLQSRNAAVVMAV AQLYWHISPKSEAGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREF QTYVKSQDKQFAAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASI LWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNVKSGA LSKYAKKIFLAQKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELVDSHYCPSCLENMPSAEAKLKKN RCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKE KVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQR LLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTH VTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AP3B1_ENST00000255194_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_3216nt ATGTCCAGCAATAGTTTTCCTTACAATGAGCAGTCCGGAGGAGGGGAGGCGACGGAGCTGGGTCAGGAGGCGACCTCAACCATTTCCCCC TCGGGGGCCTTCGGCCTCTTTAGCAGCGATTTGAAGAAGAATGAAGATCTAAAGCAAATGTTAGAGAGCAACAAAGATTCTGCTAAACTG GATGCTATGAAGCGGATTGTTGGGATGATTGCAAAAGGGAAAAATGCATCTGAACTGTTTCCTGCTGTTGTGAAGAATGTGGCCAGTAAA AATATTGAGATCAAGAAGTTGGTATATGTTTACCTGGTTCGATATGCTGAAGAACAGCAGGATCTTGCACTCCTGTCCATAAGCACTTTT CAGCGAGCTCTGAAGGACCCAAACCAACTAATTCGTGCAAGCGCTTTGAGAGTTCTGTCAAGTATTAGAGTGCCAATTATTGTACCTATC ATGATGCTTGCTATTAAGGAAGCTTCTGCTGACTTATCACCATATGTTAGGAAGAATGCAGCCCATGCAATACAAAAATTATACAGCCTT GATCCAGAGCAGAAGGAAATGTTAATTGAAGTAATTGAAAAACTTCTGAAAGATAAAAGCACATTGGTAGCTGGCAGTGTTGTGATGGCT TTTGAAGAAGTATGCCCGGACAGAATAGATCTGATTCATAAAAATTACCGCAAGCTATGTAACTTACTAGTGGATGTTGAAGAGTGGGGG CAGGTTGTCATAATCCACATGCTAACTCGATATGCTCGGACACAGTTTGTCAGCCCTTGGAAAGAGGGTGATGAATTAGAAGACAATGGA AAGAATTTCTACGAATCTGATGATGATCAGAAGGAAAAGACTGACAAAAAGAAGAAGCCGTATACTATGGATCCAGATCATAGACTCTTA ATTAGAAATACAAAGCCTTTGCTTCAGAGCAGGAATGCTGCGGTGGTTATGGCAGTTGCTCAGCTGTATTGGCACATATCACCAAAATCT GAAGCTGGCATAATTTCTAAATCACTAGTGCGTTTACTTCGTAGCAATAGGGAGGTGCAGTATATTGTCCTACAAAATATAGCAACTATG TCAATTCAAAGAAAGGGGATGTTTGAACCTTATCTGAAGAGTTTCTATGTTAGGTCAACTGATCCAACTATGATCAAGACACTGAAGCTT GAAATTTTGACAAACTTGGCAAATGAAGCCAACATATCAACTCTTCTTCGAGAATTTCAGACCTATGTGAAAAGCCAGGATAAACAATTT GCAGCAGCCACTATTCAGACTATAGGCAGATGTGCAACCAACATCTTGGAAGTCACTGACACGTGCCTCAATGGCTTGGTCTGTCTGCTG TCCAACAGGGATGAAATAGTTGTTGCTGAAAGTGTGGTTGTTATAAAGAAATTACTGCAAATGCAACCTGCACAACATGGTGAAATTATT AAACATATGGCCAAACTCCTGGACAGTATCACTGTTCCTGTTGCTAGAGCAAGTATTCTTTGGCTAATTGGAGAAAACTGTGAACGAGTT CCTAAAATTGCCCCTGATGTTTTGAGGAAGATGGCTAAAAGCTTCACTAGTGAAGATGATCTGGTAAAACTGCAGATATTAAATCTGGGA GCAAAATTGTATTTAACCAACTCCAAACAGACAAAATTGCTTACCCAGTACATATTAAATCTCGGCAAGTATGATCAAAACTACGACATC AGAGACCGTACAAGATTTATTAGGCAGCTTATTGTTCCGAATGTAAAGAGTGGAGCTTTAAGTAAATATGCCAAAAAAATATTCCTAGCA CAAAAGCCTGCACCACTGCTTGAGTCTCCTTTTAAAGATAGAGATCATTTCCAGCTTGGCACCTTATCTCATACTCTCAACATTAAAGCT ACTGGGTACCTGGAATTATCTAATTGGCCAGAGGTGGCGCCCGACCCATCAGTTCGAAATGTAGAAGTAATAGAGTTGGTGGACTCCCAT TATTGTCCCAGTTGTTTAGAAAATATGCCATCGGCTGAAGCCAAACTAAAAAAGAATAGATGTGCCAATTGTTTTGACTGTCCTGGCTGC ATGCACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGACCCAGCCAAGACCACCATGAAGAAAGCCTATTACCTG GCATGTGGATTTTGTCGCTGGACGTCTAGAGATGTGGGCATGGCAGACAAATCTGTAGCTAGTGGCGGTTGGCAGGAACCTGAAAATCCT CACACACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAAGAGAAGGTTGAGCGAGATCGCAAGAAACTGGCACGA CGTAGAAACTATATGCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAGGCTTCAGCGACCACGAGCTGGTGCATCCATCAGTACC CTTGCCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAGCCAGCTCAGGCTGTGGATGAAGTGGAACCTCTACCT GAAGACTATTATACAAGACCAGTAAATTTAACAGAGGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCT TCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTT AACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTAC ATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCT GATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTG GCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAG CGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGAC >In-frame_AP3B1_ENST00000519295_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_3069nt ATGTTAGAGAGCAACAAAGATTCTGCTAAACTGGATGCTATGAAGCGGATTGTTGGGATGATTGCAAAAGGGAAAAATGCATCTGAACTG TTTCCTGCTGTTGTGAAGAATGTGGCCAGTAAAAATATTGAGATCAAGAAGTTGGTATATGTTTACCTGGTTCGATATGCTGAAGAACAG CAGGATCTTGCACTCCTGTCCATAAGCACTTTTCAGCGAGCTCTGAAGGACCCAAACCAACTAATTCGTGCAAGCGCTTTGAGAGTTCTG TCAAGTATTAGAGTGCCAATTATTGTACCTATCATGATGCTTGCTATTAAGGAAGCTTCTGCTGACTTATCACCATATGTTAGGAAGAAT GCAGCCCATGCAATACAAAAATTATACAGCCTTGATCCAGAGCAGAAGGAAATGTTAATTGAAGTAATTGAAAAACTTCTGAAAGATAAA AGCACATTGGTAGCTGGCAGTGTTGTGATGGCTTTTGAAGAAGTATGCCCGGACAGAATAGATCTGATTCATAAAAATTACCGCAAGCTA TGTAACTTACTAGTGGATGTTGAAGAGTGGGGGCAGGTTGTCATAATCCACATGCTAACTCGATATGCTCGGACACAGTTTGTCAGCCCT TGGAAAGAGGGTGATGAATTAGAAGACAATGGAAAGAATTTCTACGAATCTGATGATGATCAGAAGGAAAAGACTGACAAAAAGAAGAAG CCGTATACTATGGATCCAGATCATAGACTCTTAATTAGAAATACAAAGCCTTTGCTTCAGAGCAGGAATGCTGCGGTGGTTATGGCAGTT GCTCAGCTGTATTGGCACATATCACCAAAATCTGAAGCTGGCATAATTTCTAAATCACTAGTGCGTTTACTTCGTAGCAATAGGGAGGTG CAGTATATTGTCCTACAAAATATAGCAACTATGTCAATTCAAAGAAAGGGGATGTTTGAACCTTATCTGAAGAGTTTCTATGTTAGGTCA ACTGATCCAACTATGATCAAGACACTGAAGCTTGAAATTTTGACAAACTTGGCAAATGAAGCCAACATATCAACTCTTCTTCGAGAATTT CAGACCTATGTGAAAAGCCAGGATAAACAATTTGCAGCAGCCACTATTCAGACTATAGGCAGATGTGCAACCAACATCTTGGAAGTCACT GACACGTGCCTCAATGGCTTGGTCTGTCTGCTGTCCAACAGGGATGAAATAGTTGTTGCTGAAAGTGTGGTTGTTATAAAGAAATTACTG CAAATGCAACCTGCACAACATGGTGAAATTATTAAACATATGGCCAAACTCCTGGACAGTATCACTGTTCCTGTTGCTAGAGCAAGTATT CTTTGGCTAATTGGAGAAAACTGTGAACGAGTTCCTAAAATTGCCCCTGATGTTTTGAGGAAGATGGCTAAAAGCTTCACTAGTGAAGAT GATCTGGTAAAACTGCAGATATTAAATCTGGGAGCAAAATTGTATTTAACCAACTCCAAACAGACAAAATTGCTTACCCAGTACATATTA AATCTCGGCAAGTATGATCAAAACTACGACATCAGAGACCGTACAAGATTTATTAGGCAGCTTATTGTTCCGAATGTAAAGAGTGGAGCT TTAAGTAAATATGCCAAAAAAATATTCCTAGCACAAAAGCCTGCACCACTGCTTGAGTCTCCTTTTAAAGATAGAGATCATTTCCAGCTT GGCACCTTATCTCATACTCTCAACATTAAAGCTACTGGGTACCTGGAATTATCTAATTGGCCAGAGGTGGCGCCCGACCCATCAGTTCGA AATGTAGAAGTAATAGAGTTGGTGGACTCCCATTATTGTCCCAGTTGTTTAGAAAATATGCCATCGGCTGAAGCCAAACTAAAAAAGAAT AGATGTGCCAATTGTTTTGACTGTCCTGGCTGCATGCACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGACCCA GCCAAGACCACCATGAAGAAAGCCTATTACCTGGCATGTGGATTTTGTCGCTGGACGTCTAGAGATGTGGGCATGGCAGACAAATCTGTA GCTAGTGGCGGTTGGCAGGAACCTGAAAATCCTCACACACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAAGAG AAGGTTGAGCGAGATCGCAAGAAACTGGCACGACGTAGAAACTATATGCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAGGCTT CAGCGACCACGAGCTGGTGCATCCATCAGTACCCTTGCCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAGCCA GCTCAGGCTGTGGATGAAGTGGAACCTCTACCTGAAGACTATTATACAAGACCAGTAAATTTAACAGAGGTAACAACCCTTCAGCAGCGT CTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGT AAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAA GTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCAT GTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCT GGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAAC AAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTG GCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AP3B1_ENST00000255194_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_6101nt ACTGCGCATGCGCAGGGGGTGGACTGCCAGGTCGGCTCAGGGAGCCGTGACGAGTCCGGAAGCGCCTGCGCGCGCTCCTCCGTACGAGAA CTAGTTTTGTTCCGTGCCCTCTGGACTGGAACCTTTTGGAGAGAACCCCCGGCAGGACCAACCCCGCACCCGCCAGCACCGCGGCAATGT CCAGCAATAGTTTTCCTTACAATGAGCAGTCCGGAGGAGGGGAGGCGACGGAGCTGGGTCAGGAGGCGACCTCAACCATTTCCCCCTCGG GGGCCTTCGGCCTCTTTAGCAGCGATTTGAAGAAGAATGAAGATCTAAAGCAAATGTTAGAGAGCAACAAAGATTCTGCTAAACTGGATG CTATGAAGCGGATTGTTGGGATGATTGCAAAAGGGAAAAATGCATCTGAACTGTTTCCTGCTGTTGTGAAGAATGTGGCCAGTAAAAATA TTGAGATCAAGAAGTTGGTATATGTTTACCTGGTTCGATATGCTGAAGAACAGCAGGATCTTGCACTCCTGTCCATAAGCACTTTTCAGC GAGCTCTGAAGGACCCAAACCAACTAATTCGTGCAAGCGCTTTGAGAGTTCTGTCAAGTATTAGAGTGCCAATTATTGTACCTATCATGA TGCTTGCTATTAAGGAAGCTTCTGCTGACTTATCACCATATGTTAGGAAGAATGCAGCCCATGCAATACAAAAATTATACAGCCTTGATC CAGAGCAGAAGGAAATGTTAATTGAAGTAATTGAAAAACTTCTGAAAGATAAAAGCACATTGGTAGCTGGCAGTGTTGTGATGGCTTTTG AAGAAGTATGCCCGGACAGAATAGATCTGATTCATAAAAATTACCGCAAGCTATGTAACTTACTAGTGGATGTTGAAGAGTGGGGGCAGG TTGTCATAATCCACATGCTAACTCGATATGCTCGGACACAGTTTGTCAGCCCTTGGAAAGAGGGTGATGAATTAGAAGACAATGGAAAGA ATTTCTACGAATCTGATGATGATCAGAAGGAAAAGACTGACAAAAAGAAGAAGCCGTATACTATGGATCCAGATCATAGACTCTTAATTA GAAATACAAAGCCTTTGCTTCAGAGCAGGAATGCTGCGGTGGTTATGGCAGTTGCTCAGCTGTATTGGCACATATCACCAAAATCTGAAG CTGGCATAATTTCTAAATCACTAGTGCGTTTACTTCGTAGCAATAGGGAGGTGCAGTATATTGTCCTACAAAATATAGCAACTATGTCAA TTCAAAGAAAGGGGATGTTTGAACCTTATCTGAAGAGTTTCTATGTTAGGTCAACTGATCCAACTATGATCAAGACACTGAAGCTTGAAA TTTTGACAAACTTGGCAAATGAAGCCAACATATCAACTCTTCTTCGAGAATTTCAGACCTATGTGAAAAGCCAGGATAAACAATTTGCAG CAGCCACTATTCAGACTATAGGCAGATGTGCAACCAACATCTTGGAAGTCACTGACACGTGCCTCAATGGCTTGGTCTGTCTGCTGTCCA ACAGGGATGAAATAGTTGTTGCTGAAAGTGTGGTTGTTATAAAGAAATTACTGCAAATGCAACCTGCACAACATGGTGAAATTATTAAAC ATATGGCCAAACTCCTGGACAGTATCACTGTTCCTGTTGCTAGAGCAAGTATTCTTTGGCTAATTGGAGAAAACTGTGAACGAGTTCCTA AAATTGCCCCTGATGTTTTGAGGAAGATGGCTAAAAGCTTCACTAGTGAAGATGATCTGGTAAAACTGCAGATATTAAATCTGGGAGCAA AATTGTATTTAACCAACTCCAAACAGACAAAATTGCTTACCCAGTACATATTAAATCTCGGCAAGTATGATCAAAACTACGACATCAGAG ACCGTACAAGATTTATTAGGCAGCTTATTGTTCCGAATGTAAAGAGTGGAGCTTTAAGTAAATATGCCAAAAAAATATTCCTAGCACAAA AGCCTGCACCACTGCTTGAGTCTCCTTTTAAAGATAGAGATCATTTCCAGCTTGGCACCTTATCTCATACTCTCAACATTAAAGCTACTG GGTACCTGGAATTATCTAATTGGCCAGAGGTGGCGCCCGACCCATCAGTTCGAAATGTAGAAGTAATAGAGTTGGTGGACTCCCATTATT GTCCCAGTTGTTTAGAAAATATGCCATCGGCTGAAGCCAAACTAAAAAAGAATAGATGTGCCAATTGTTTTGACTGTCCTGGCTGCATGC ACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGACCCAGCCAAGACCACCATGAAGAAAGCCTATTACCTGGCAT GTGGATTTTGTCGCTGGACGTCTAGAGATGTGGGCATGGCAGACAAATCTGTAGCTAGTGGCGGTTGGCAGGAACCTGAAAATCCTCACA CACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAAGAGAAGGTTGAGCGAGATCGCAAGAAACTGGCACGACGTA GAAACTATATGCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAGGCTTCAGCGACCACGAGCTGGTGCATCCATCAGTACCCTTG CCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAGCCAGCTCAGGCTGTGGATGAAGTGGAACCTCTACCTGAAG ACTATTATACAAGACCAGTAAATTTAACAGAGGTAACAACCCTTCAGCAGCGTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCAC AGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCCGTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACC CAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAGAAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGA AGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCCATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATG ATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAGCTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAG AACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCAACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTG AGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACCTGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGG GAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCACTTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAA GGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATTAGGCCTTGTTTATAACGATGTACCCATGCACTACGGAAT TCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTAGCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGT AAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAATTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGG CATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCACTAAGGATCACAATGTCACAGATGAAACTTAAATGATAA CCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAACTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTA AAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCATATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTAT CATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCTCTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCT TAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCAAACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCAT TCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGGCAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTC TGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCCAAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCA GAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTTCCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTT GAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTTTTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTA AACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGACTTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAA CCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACCAGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGT GGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTTTTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGA ATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATATTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAA AGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACAGTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGA AAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTGGAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAG AAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCACTACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATT TGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACACGTTTGCATAGACTACACACATGTCATGCGTTTATGGCA GGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCATCATTCCCATACACAGAAACACAAAACACTTTGATCATAA ACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGTTTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTA TTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAATTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAA AATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTAGCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTA ATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGTGCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGT GAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATCTTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAA CTTAATGTAGTGAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGCTCTCATGTAGATACTAAGTAGCATGGCTCAGAGCCAAAA GACAAGCGTGAAGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTCCCTTCCATTCCTTAAATGAAGTAATCTAAAATCTCTTAG CAGGTTAGTTCACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATATACATATTCACAGAACCATTATATAAATGTTGTTAGACC >In-frame_AP3B1_ENST00000519295_chr5_77423854_-_DCTN4_ENST00000447998_chr5_150136049_-_6050nt GCCTGCGCGCGCTCCTCCGTACGAGAACTAGTTTTGTTCCGTGCCCTCTGGACTGGAACCTTTTGGAGAGAACCCCCGGCAGGACCAACC CCGCACCCGCCAGCACCGCGGCAATGTCCAGCAATAGTTTTCCTTACAATGAGCAGTCCGGAGGAGGGGAGGCGACGGAGCTGGGTCAGG AGGCGACCTCAACCATTTCCCCCTCGGGGGCCTTCGGCCTCTTTAGCAGCGATTTGAAGAAGTGAGGAGAAAGGAATGAAGATCTAAAGC AAATGTTAGAGAGCAACAAAGATTCTGCTAAACTGGATGCTATGAAGCGGATTGTTGGGATGATTGCAAAAGGGAAAAATGCATCTGAAC TGTTTCCTGCTGTTGTGAAGAATGTGGCCAGTAAAAATATTGAGATCAAGAAGTTGGTATATGTTTACCTGGTTCGATATGCTGAAGAAC AGCAGGATCTTGCACTCCTGTCCATAAGCACTTTTCAGCGAGCTCTGAAGGACCCAAACCAACTAATTCGTGCAAGCGCTTTGAGAGTTC TGTCAAGTATTAGAGTGCCAATTATTGTACCTATCATGATGCTTGCTATTAAGGAAGCTTCTGCTGACTTATCACCATATGTTAGGAAGA ATGCAGCCCATGCAATACAAAAATTATACAGCCTTGATCCAGAGCAGAAGGAAATGTTAATTGAAGTAATTGAAAAACTTCTGAAAGATA AAAGCACATTGGTAGCTGGCAGTGTTGTGATGGCTTTTGAAGAAGTATGCCCGGACAGAATAGATCTGATTCATAAAAATTACCGCAAGC TATGTAACTTACTAGTGGATGTTGAAGAGTGGGGGCAGGTTGTCATAATCCACATGCTAACTCGATATGCTCGGACACAGTTTGTCAGCC CTTGGAAAGAGGGTGATGAATTAGAAGACAATGGAAAGAATTTCTACGAATCTGATGATGATCAGAAGGAAAAGACTGACAAAAAGAAGA AGCCGTATACTATGGATCCAGATCATAGACTCTTAATTAGAAATACAAAGCCTTTGCTTCAGAGCAGGAATGCTGCGGTGGTTATGGCAG TTGCTCAGCTGTATTGGCACATATCACCAAAATCTGAAGCTGGCATAATTTCTAAATCACTAGTGCGTTTACTTCGTAGCAATAGGGAGG TGCAGTATATTGTCCTACAAAATATAGCAACTATGTCAATTCAAAGAAAGGGGATGTTTGAACCTTATCTGAAGAGTTTCTATGTTAGGT CAACTGATCCAACTATGATCAAGACACTGAAGCTTGAAATTTTGACAAACTTGGCAAATGAAGCCAACATATCAACTCTTCTTCGAGAAT TTCAGACCTATGTGAAAAGCCAGGATAAACAATTTGCAGCAGCCACTATTCAGACTATAGGCAGATGTGCAACCAACATCTTGGAAGTCA CTGACACGTGCCTCAATGGCTTGGTCTGTCTGCTGTCCAACAGGGATGAAATAGTTGTTGCTGAAAGTGTGGTTGTTATAAAGAAATTAC TGCAAATGCAACCTGCACAACATGGTGAAATTATTAAACATATGGCCAAACTCCTGGACAGTATCACTGTTCCTGTTGCTAGAGCAAGTA TTCTTTGGCTAATTGGAGAAAACTGTGAACGAGTTCCTAAAATTGCCCCTGATGTTTTGAGGAAGATGGCTAAAAGCTTCACTAGTGAAG ATGATCTGGTAAAACTGCAGATATTAAATCTGGGAGCAAAATTGTATTTAACCAACTCCAAACAGACAAAATTGCTTACCCAGTACATAT TAAATCTCGGCAAGTATGATCAAAACTACGACATCAGAGACCGTACAAGATTTATTAGGCAGCTTATTGTTCCGAATGTAAAGAGTGGAG CTTTAAGTAAATATGCCAAAAAAATATTCCTAGCACAAAAGCCTGCACCACTGCTTGAGTCTCCTTTTAAAGATAGAGATCATTTCCAGC TTGGCACCTTATCTCATACTCTCAACATTAAAGCTACTGGGTACCTGGAATTATCTAATTGGCCAGAGGTGGCGCCCGACCCATCAGTTC GAAATGTAGAAGTAATAGAGTTGGTGGACTCCCATTATTGTCCCAGTTGTTTAGAAAATATGCCATCGGCTGAAGCCAAACTAAAAAAGA ATAGATGTGCCAATTGTTTTGACTGTCCTGGCTGCATGCACACCCTCTCTACTCGGGCCACGAGCATCTCCACACAGCTTCCAGATGACC CAGCCAAGACCACCATGAAGAAAGCCTATTACCTGGCATGTGGATTTTGTCGCTGGACGTCTAGAGATGTGGGCATGGCAGACAAATCTG TAGCTAGTGGCGGTTGGCAGGAACCTGAAAATCCTCACACACAACGGATGAACAAATTGATTGAATATTACCAGCAGCTTGCTCAGAAAG AGAAGGTTGAGCGAGATCGCAAGAAACTGGCACGACGTAGAAACTATATGCCTCTGGCTTTTTCGGACAAATATGGTCTTGGAACCAGGC TTCAGCGACCACGAGCTGGTGCATCCATCAGTACCCTTGCCGGACTTTCCCTTAAAGAAGGAGAGGATCAGAAAGAGATAAAGATTGAGC CAGCTCAGGCTGTGGATGAAGTGGAACCTCTACCTGAAGACTATTATACAAGACCAGTAAATTTAACAGAGGTAACAACCCTTCAGCAGC GTCTGTTACAGCCTGACTTCCAGCCAGTCTGTGCTTCACAGCTCTATCCTCGCCACAAACATCTTCTGATCAAACGGTCCCTGCGCTGCC GTAAATGTGAACATAATTTGAGCAAGCCAGAATTTAACCCAACGTCAATCAAATTCAAAATCCAGCTGGTCGCTGTCAATTATATTCCAG AAGTGAGAATCATGTCAATTCCCAACCTTCGCTACATGAAGGAGAGCCAGGTCCTCCTGACTCTTACAAATCCAGTTGAGAACCTCACCC ATGTGACTCTCTTCGAGTGTGAGGAGGGGGACCCTGATGATATCAACAGCACTGCTAAGGTGGTGGTGCCTCCCAAAGAGCTCGTTTTAG CTGGCAAGGATGCAGCAGCAGAGTACGATGAGTTGGCAGAACCTCAAGACTTTCAGGACGATCCTGACATTATAGCCTTCAGAAAGGCCA ACAAAGTGGGTATTTTCATCAAAGTTACACCACAGCGTGAGGAGGGTGAAGTGACCGTGTGCTTCAAGATGAAGCATGATTTTAAAAACC TGGCAGCCCCCATTCGCCCCATTGAAGAAAGTGACCAGGGAACAGAAGTCATCTGGCTCACCCAGCATGTGGAACTTAGCTTGGGCCCAC TTCTTCCTTAAAAGGTTCCACTGGAGGGCAGATCCCAAAGGACAGTATCACCGTAAACCTGCGTTAAAATGTGGAAGCTGCTGCTTCATT AGGCCTTGTTTATAACGATGTACCCATGCACTACGGAATTCTATTGCTAAGAAAGTGGGAGCATAGGCAAGGCATTGGGAACACAGGGTA GCTGCTGTTGCTCTTGCTCTCACCCCTGTTGACACCAGTAAGTCTGTGTCTCCCTCACTGAACCCTGCACGTTGAGTAACAGCAGCATAA TTCCATCCTAGGAAAGGGGATGGGTGTTCCTTGGAATGGCATTGTATTTACCACCTGAGAAACTCTGTACTGTCTCTTGATCTGATCTCA CTAAGGATCACAATGTCACAGATGAAACTTAAATGATAACCCAAAGGTAGACCTGCTGTTAATGATCCAGCATTGGTCACAATGTACCAA CTGCTTTCTGCATTCCGTTAAATATCATCTAACAGTCTAAAACATATCCCTTCATTGCCATAATGGCTGCCATTTTGCCATAGATTTCCA TATAACTGAAAAACTGAATTGTCACTTTATCTTTAGTATCATGATGATTGGAAAAACCTGTGAAGTTGTTAAGGCACTCTCATTTGCCCT CTTTTTCTAAGTGAATACAGGACACGTATTAGTTGTTCTTAATTTTTTTCCCAGTAAAATATGGATCTTTTAAGAAGAATTTGAGAAGCA AACAATTACATGTCATGTCAAGGGGGTAGCAGATTCCATTCGTTTTCAATATTGCCACAATACCCAGGGATTAATGCTGCCACAGGGGGG CAATCTTTATTTGTCTTACTTCCTACCCCTTCCCTGTTCTGCCTCTTTAACTCAGTTAAGTTGTTCTGTTTGGGACCTGGAAAAGAACCC AAAGAAAACCTGAGTGGACAGGTTCATTTCTGGAATGCAGAAAACATTTTAAAGGCTAGATTTTTAGAATATTCTCAACTAGCATTCTTT CCATTGATTTGAAGGGGAAATTAACTATTATAATCTCTTGAATCCAAAACTGGATATTAAGAACTTTCCCCCTTACTAAGTTTAAGACTT TTGTCATGTGGTGAGTCAAATAAGACCATTTTGATTGTAAACCATAAAATAGTTCAGCAAGTAGCCCACAGTTCTGGCCTAACAGCAGAC TTGCTGTTTTCACTTGGTATCCTGGAGTTGGGTTGCTAACCTTAATTTCTATGATGTTTTCTAAAATGAAACTTGATAAAGTAGACCACC AGCTGCACCGTGTTTTCTGTAAAAGTATTGTTAGTAAGTGGCCAAGAGACTTGAGGAAAATACAGATTTTTTGTTTACCTTGGTCTTGTT TTAAGTCTTAAAAAATTAAAGATAACATTATAATGTAGAATACAGATGGGACATAGTCCTTGTAAGCTTCCCTTGAAAATGTTTTAAATA TTTAGGAAGCTTTTAAAAGACACTAAATTGTACTCTAAAAGACACTAAATTGTACTAATTGTACAAAGGTCAAGCCAATTTTATGAAACA GTCCTACAGAGTAATATATGTGATGCAGTGTAAGAAGGAAAATACTCATCTCTAACATTATGGTAATAACATTTAGCCTCTTAGGAGTTG GAGCAGGGGGATGGGTAATTACAGATTTGCAGACTATAGAAAGAGTTTCATTTTTTTGTGACCCCACAGAGTCTCAAATTTTTATTTCAC TACCTGCTAGAGCCTACTGTGAAATCACTGCTCCATATTTGCCAGTGGAGGAAATGGGCATAGAGTAGAGAATAGCTTCATATGTTTACA CGTTTGCATAGACTACACACATGTCATGCGTTTATGGCAGGTAGCTGGTATTTATTCCCCAAAGTAATAATGTTGAAGTATGGGTCTCAT CATTCCCATACACAGAAACACAAAACACTTTGATCATAAACTTTTTTCTTCAGAAGCCAAACTAACTTGCAGAATAATAGAGCCACTGGT TTAATGTTTCCTCAAGATAGGTTTTAGTGTAAGCTAGTATTCTGTGTGTTCGTAGAAATGATTCAATACCTGCAGCTGGTGAATTAGGAA TTGTATTTGTTGCCTTTTTTATATTAGATGAGGTGCAAAAATTTTAATGCTAGTCAGTATGCACCACCACAGGAAAGTTAGATCCCATTA GCACTTGAAACTACAGCTTTGGAAACTTAGGCTAAGTTAATTTGGATTTGTTACTTGATTCACCTACTGACCTTTTCTTTTGTTTGAAGT GCTTATCAGCATAATGAGCTAAGTGTCATGCATATTTGTGAAGAAACACCCTTTTTGGTCCCTTTTGGGACAGAGAGGTACTCCTTGATC TTTATGAATGACAGGTTACTGTTTTGCCTTATTGCTTAACTTAATGTAGTGAAATAAAGCAGACAAAGCTTGAGCGTGTCTTTTGTTTGC TCTCATGTAGATACTAAGTAGCATGGCTCAGAGCCAAAAGACAAGCGTGAAGTTAAGAGAGTTGGCTAAGAGAGTTGGTGGGGCATGCTC CCTTCCATTCCTTAAATGAAGTAATCTAAAATCTCTTAGCAGGTTAGTTCACCATAATATATAAGTAGATGTTGCTTTGAGCTTCTTATA TACATATTCACAGAACCATTATATAAATGTTGTTAGACCTCTACCAGTTTTTATCCTGGGTCATTGCTTCTAAAGATATCCTTTACAATA |
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FusionGenePPI for AP3B1_DCTN4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AP3B1 | ARRB2, ARRB1, SLC30A3, ARF5, ARF6, AP3S2, GRK5, AP3D1, AP3S1, AP3M1, COG3, SEPT7, LRSAM1, VTI1B, SNX11, AGO3, CREB3, FAM9A, DTNBP1, EDA, PTGER3, EPB41L3, NTRK1, CDK11A, CDC73, JMJD6, PELP1, ATR, ATM, CENPJ, XPO1, DLG3, YWHAZ, NLRP3, SKA3, SNW1, DUSP14, CAMKV, AP3M2, PIP4K2A, TMEM63A, VASN, TPCN2, ERMAP, EPB41L2, FGF8, CREB3L1, PES1, EPB41L5, EAF1, DDX20, POLD1, MFAP1, NAF1, EIF2AK1, NOLC1, ATRX, RBM14, CCDC154, MCM3, PRPF38A, TRIM25 | DCTN4 | ACTR1A, ATP7B, ACTR10, ACTR1B, DCTN2, AKAP10, SEH1L, GOLGA2, PNMA1, CALCOCO2, MTUS2, CSPP1, C4BPB, CAPZA2, GPS2, CAPZA1, CAPZB, DCTN1, DCTN5, DCTN6, EIF4G1, NTRK1, KRAS, DYNC1H1, DUSP13, KLHL2, RIC8A, DEFB127, PDGFD, C16orf45, MIS18A, RPS19BP1, UQCRH, MAPK8IP3, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AP3B1_DCTN4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AP3B1_DCTN4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | AP3B1 | C1842362 | HERMANSKY-PUDLAK SYNDROME 2 | 1 | CTD_human;ORPHANET;UNIPROT |
| Tgene | DCTN4 | C0010674 | Cystic Fibrosis | 1 | CTD_human;ORPHANET |
| Tgene | DCTN4 | C0033817 | Pseudomonas Infections | 1 | CTD_human |
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