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Fusion gene ID: 20702 |
FusionGeneSummary for MAML2_CRTC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAML2_CRTC1 | Fusion gene ID: 20702 | Hgene | Tgene | Gene symbol | MAML2 | CRTC1 | Gene ID | 84441 | 23373 |
| Gene name | mastermind like transcriptional coactivator 2 | CREB regulated transcription coactivator 1 | |
| Synonyms | MAM-3|MAM2|MAM3|MLL-MAML2 | MECT1|TORC-1|TORC1|WAMTP1 | |
| Cytomap | 11q21 | 19p13.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mastermind-like protein 2mam-2mastermind-like 2 | CREB-regulated transcription coactivator 1mucoepidermoid carcinoma translocated protein 1transducer of regulated cAMP response element-binding protein (CREB) 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8IZL2 | Q6UUV9 | |
| Ensembl transtripts involved in fusion gene | ENST00000524717, | ENST00000321949, ENST00000338797, ENST00000594658, ENST00000601916, | |
| Fusion gene scores | * DoF score | 11 X 8 X 5=440 | 5 X 3 X 4=60 |
| # samples | 12 | 5 | |
| ** MAII score | log2(12/440*10)=-1.87446911791614 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAML2 [Title/Abstract] AND CRTC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MAML2 | GO:0007219 | Notch signaling pathway | 12370315 |
| Hgene | MAML2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12370315 |
| Tgene | CRTC1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 14536081 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AY186998 | MAML2 | chr11 | 96074547 | - | CRTC1 | chr19 | 18853719 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000524717 | ENST00000321949 | MAML2 | chr11 | 96074547 | - | CRTC1 | chr19 | 18853719 | + |
| In-frame | ENST00000524717 | ENST00000338797 | MAML2 | chr11 | 96074547 | - | CRTC1 | chr19 | 18853719 | + |
| In-frame | ENST00000524717 | ENST00000594658 | MAML2 | chr11 | 96074547 | - | CRTC1 | chr19 | 18853719 | + |
| In-frame | ENST00000524717 | ENST00000601916 | MAML2 | chr11 | 96074547 | - | CRTC1 | chr19 | 18853719 | + |
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FusionProtFeatures for MAML2_CRTC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAML2 | CRTC1 |
| Acts as a transcriptional coactivator for NOTCHproteins. Has been shown to amplify NOTCH-induced transcription ofHES1. Potentiates activation by NOTCH3 and NOTCH4 more efficientlythan MAML1 or MAML3. {ECO:0000269|PubMed:12370315,ECO:0000269|PubMed:12386158, ECO:0000269|PubMed:12539049}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CRTC1 | chr11:96074547 | chr19:18853719 | ENST00000321949 | + | 0 | 14 | 299_366 | 42 | 635 | Compositional bias | Note=Ser-rich |
| Tgene | >CRTC1 | chr11:96074547 | chr19:18853719 | ENST00000338797 | + | 0 | 15 | 299_366 | 42 | 651 | Compositional bias | Note=Ser-rich |
| Tgene | >CRTC1 | chr11:96074547 | chr19:18853719 | ENST00000321949 | + | 0 | 14 | 242_258 | 42 | 635 | Motif | Nuclear export signal |
| Tgene | >CRTC1 | chr11:96074547 | chr19:18853719 | ENST00000338797 | + | 0 | 15 | 242_258 | 42 | 651 | Motif | Nuclear export signal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MAML2_CRTC1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000321949_chr19_18853719_+_764aa MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQLQKSQYL QLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPP ADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQEN TTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR RQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP PLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANAL SHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDS >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000338797_chr19_18853719_+_780aa MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQLQKSQYL QLGPSRGQYYGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHG RQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKS CEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ HRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPG GPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFG DAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSK >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000594658_chr19_18853719_+_764aa MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQLQKSQYL QLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPP ADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQEN TTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR RQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP PLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANAL SHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDS >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000601916_chr19_18853719_+_597aa MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAG KHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQLQKSQYL QLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPP ADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQEN TTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR RQQASPTLSPLSPITQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000321949_chr19_18853719_+_2292nt ATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCTCCTTGGAGGGGGCTCAGTCACCCCG AGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCTGAGCTGTGAAGGACGATATGAACGA GGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCATGGCCAGGGGGCAAGGAAAGCTGGC AAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCCTCCTGCGGCCTCCCAAGCAGCAGCA ACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAGCAATAATGGTGGCAGTGGTGGGATA AACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCC TACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCA CCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCC CCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCG CCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGG AGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTG TCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAG GCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATC ATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCC GACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCC >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000338797_chr19_18853719_+_2340nt ATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCTCCTTGGAGGGGGCTCAGTCACCCCG AGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCTGAGCTGTGAAGGACGATATGAACGA GGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCATGGCCAGGGGGCAAGGAAAGCTGGC AAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCCTCCTGCGGCCTCCCAAGCAGCAGCA ACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAGCAATAATGGTGGCAGTGGTGGGATA AACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG CCCAGCGGATTTCTGGGGGAGGCCCTGGCAGCGGCTCCTGTCTCTCTGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACC CGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGA CGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTG CACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTC CCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCC TGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCC CTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCC AGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAG CACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATC ACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCG CAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGT GGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCC CCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCC AACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGG GACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATC AGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCG GACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAA GAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTG ACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGA >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000594658_chr19_18853719_+_2292nt ATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCTCCTTGGAGGGGGCTCAGTCACCCCG AGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCTGAGCTGTGAAGGACGATATGAACGA GGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCATGGCCAGGGGGCAAGGAAAGCTGGC AAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCCTCCTGCGGCCTCCCAAGCAGCAGCA ACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAGCAATAATGGTGGCAGTGGTGGGATA AACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCC TACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCA CCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCC CCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCG CCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGG AGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTG TCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAG GCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATC ATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCC GACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCC >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000601916_chr19_18853719_+_1791nt ATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCTCCTTGGAGGGGGCTCAGTCACCCCG AGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCTGAGCTGTGAAGGACGATATGAACGA GGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCATGGCCAGGGGGCAAGGAAAGCTGGC AAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCCTCCTGCGGCCTCCCAAGCAGCAGCA ACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAGCAATAATGGTGGCAGTGGTGGGATA AACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGC AGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAG CAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACC AGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000321949_chr19_18853719_+_4147nt CTCCCTCTCCTATCGGAGCACAATGAAAGCCTGTGTATCGCCGTGACTCCGGGCGCGAGCCAGTGTCAGCAAAGCGGCTAACAACAGACG AGAAAGAGAAAGGAAAATACAAGCTACTTTTTTTTTCCATCTATAAAGCGGAGCAAATACAGGAGATAGAACCAGATTGCTTATTGCGAG TCCAGACCCTCAGATCCACTGGCCGGGGATGGAATGTACAAAAGTGGACAGAAAAGTGGCTGGACATGACTCGGTGCAATTTGCTGGAAG TTTGTAAGTTTGACCATCGTTTGTAAATTACTCTCGGAAGAGTTTGTCTCTCTTGATACTGTATTAGAATAGAGCCGGGGGTGAGGAATA GAAACGTAAGCGGGAAAGAAAAAAATGTGTTGAAGGATCTCTCTCAGTGGCTAGCGACTTAAGATTGCTTTTCATTTAAGGCTAGGAAAC CTTAGAGGGAGTGAGGATTTTACCGGTGATTGGATTAGCTGAAGAAAAAAGCATGGTCCAAAAGTCCAATTACTGACATTGTTAACAGTT GAAAAGCTGTCTCCCTCTTTTGGGAGAAGACAACATCCTACAGTACCCCAAAGAGGAGAAAACACCGGAGCGAAAGGAAAGGGAGGAAAA ATTAAAAGCCAAAAGACAGTCTCCCTTGATTTTTGCACATTTTGAACAGTGACTTAAACATCTTCTGAAACAGCACTGTTTTGTTTTGTT TTGGTTTTTTATTTAACCTGAGGAAAAGTCAAGGCTGCTGGTTACATAGACATGGTAGAAATGTGTTTCTCTGCAGAAACATCCCCATAA AGAATTGTCGGAAACAACTAGGTGAGGGGGAGTCCTCTCTATTAATACCTCTCTCAATACCTTTTGCTGTGTGTTTCTGTCTCTTGCTGG ACAATCCCTGAATTCTTGATCTAACCCCCAGATCGTGTGTTTACAAAGTACCTAGTGGCTCTTGTCAGCTTGGTGGAGGAAAAAAAATCC ACCAACTCTGTCCAACTTCTCCAGAGCTGTCAAATGCAATTAGAGTAAGTTAATCAGGGTTTGTTTCCAACTTATCCTCCCCCCAGTTGG TTTCTATTCTTTCTCCCCACCCTCTTTTTACTAACTCCCCTCCCCCACAACTTCTCCACGGCTCCCCCACAACCTCTGAAGACCTCTATT CATGTGGCCCTGAACACTGAGCTCACATTGTCAAAAACAGACTTGCCTGCAATAGCCAGCAGTAGCCTCTTTCCACCTCACCATCCCAGA GGCAGCAATCATTGTGTCCGGTAAGATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCT CCTTGGAGGGGGCTCAGTCACCCCGAGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCT GAGCTGTGAAGGACGATATGAACGAGGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCA TGGCCAGGGGGCAAGGAAAGCTGGCAAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCC TCCTGCGGCCTCCCAAGCAGCAGCAACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAG CAATAATGGTGGCAGTGGTGGGATAAACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCT CCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAG TGGCACCATGGACCTGCCCTTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAG GGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTA TGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCAC GCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATC AGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACAT CTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCA CTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGC CAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCC CCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGC CCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCC TCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAG CCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATC GATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGT CTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGAT GGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCC GGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGC CAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGG GGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCT CAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCG CTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAAT GCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACC CGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCG GGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGG GCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAG CCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCCAGAGCGCGGGGCAGACGCAAAGTGAAATAAACACTATTT >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000338797_chr19_18853719_+_8437nt CTCCCTCTCCTATCGGAGCACAATGAAAGCCTGTGTATCGCCGTGACTCCGGGCGCGAGCCAGTGTCAGCAAAGCGGCTAACAACAGACG AGAAAGAGAAAGGAAAATACAAGCTACTTTTTTTTTCCATCTATAAAGCGGAGCAAATACAGGAGATAGAACCAGATTGCTTATTGCGAG TCCAGACCCTCAGATCCACTGGCCGGGGATGGAATGTACAAAAGTGGACAGAAAAGTGGCTGGACATGACTCGGTGCAATTTGCTGGAAG TTTGTAAGTTTGACCATCGTTTGTAAATTACTCTCGGAAGAGTTTGTCTCTCTTGATACTGTATTAGAATAGAGCCGGGGGTGAGGAATA GAAACGTAAGCGGGAAAGAAAAAAATGTGTTGAAGGATCTCTCTCAGTGGCTAGCGACTTAAGATTGCTTTTCATTTAAGGCTAGGAAAC CTTAGAGGGAGTGAGGATTTTACCGGTGATTGGATTAGCTGAAGAAAAAAGCATGGTCCAAAAGTCCAATTACTGACATTGTTAACAGTT GAAAAGCTGTCTCCCTCTTTTGGGAGAAGACAACATCCTACAGTACCCCAAAGAGGAGAAAACACCGGAGCGAAAGGAAAGGGAGGAAAA ATTAAAAGCCAAAAGACAGTCTCCCTTGATTTTTGCACATTTTGAACAGTGACTTAAACATCTTCTGAAACAGCACTGTTTTGTTTTGTT TTGGTTTTTTATTTAACCTGAGGAAAAGTCAAGGCTGCTGGTTACATAGACATGGTAGAAATGTGTTTCTCTGCAGAAACATCCCCATAA AGAATTGTCGGAAACAACTAGGTGAGGGGGAGTCCTCTCTATTAATACCTCTCTCAATACCTTTTGCTGTGTGTTTCTGTCTCTTGCTGG ACAATCCCTGAATTCTTGATCTAACCCCCAGATCGTGTGTTTACAAAGTACCTAGTGGCTCTTGTCAGCTTGGTGGAGGAAAAAAAATCC ACCAACTCTGTCCAACTTCTCCAGAGCTGTCAAATGCAATTAGAGTAAGTTAATCAGGGTTTGTTTCCAACTTATCCTCCCCCCAGTTGG TTTCTATTCTTTCTCCCCACCCTCTTTTTACTAACTCCCCTCCCCCACAACTTCTCCACGGCTCCCCCACAACCTCTGAAGACCTCTATT CATGTGGCCCTGAACACTGAGCTCACATTGTCAAAAACAGACTTGCCTGCAATAGCCAGCAGTAGCCTCTTTCCACCTCACCATCCCAGA GGCAGCAATCATTGTGTCCGGTAAGATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCT CCTTGGAGGGGGCTCAGTCACCCCGAGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCT GAGCTGTGAAGGACGATATGAACGAGGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCA TGGCCAGGGGGCAAGGAAAGCTGGCAAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCC TCCTGCGGCCTCCCAAGCAGCAGCAACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAG CAATAATGGTGGCAGTGGTGGGATAAACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCT CCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAG TGGCACCATGGACCTGCCCTTCCAGCCCAGCGGATTTCTGGGGGAGGCCCTGGCAGCGGCTCCTGTCTCTCTGACCCCCTTCCAATCCTC GGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCG GCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAG AAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCA GAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAA GAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCC CGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCC CACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAAT GAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCC CACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCA GGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACA GGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGT ACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTA CCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACAC TTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCA GTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCT CACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGG AGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCT GGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGA CACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCG TGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACC TCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTC CCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTC CCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCT CACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGA GGAGGCGCCAGAGCGCGGGGCAGACGCAAAGTGAAATAAACACTATTTTGACGGCTGTCTTTTATATTTCTGAGCACACACAGAGCCCTG GCGTCCACCGGGGCAGGCGCAAAGTGGACAGAGCATGCAGGGCGGCGGACCCCCCCACGACCCTCCTCGCCCTGTCTCCATCCCCTCGAA GCCCTGCCTCACCGCAGGCAGGCCCATCGGTGGCCACCTTTGCCGGGAAGTGACCGGAAGGCCCCGTGAGGGGTCGAACGCGGAGGCAGG GGTTACCTCTTGGGGCTTTACAATCCGTGGCCCCTCCTGTCCTGCACTGTGGTCACCGGTCCTGTCATAGATGCTGTTAATTTAAGGTAC AGGCAGAGGTGGCCAGGGGAGTTTCATTGTGGTTTTTTTTTCCTTTTAGTTTCTAGTTACATTTTGGTTGTAGATGACTCGCTTAATCTT TTAAGCCAACACTTGCCTGAGAGCATGTTTTTATTTCAGAAATCCAACTTTACCTATTTTTTAAGCTAACTGGAAATGGAGGCCATGCGC CCCAAAGCAGCCCGCCACCCACCTGAGTGTAAGAAGTGAGTCCGGCTTTTGGGTTTCACCCCAAGTTATCTCAAAACAAAAGGGCTGGTC AGGCTGGGCAGGGCCTTGTCAGGAGCTCACGGTAGGCAGAGGTGCCTCTGCCAGGGCCACAGAACAGACTTCCGGGAAGGGGCCTTGGCT TTTATTGAGGGTCTCTCAAAGACCCAGCCTGCCAGCCTCTCCCAGAGGTGCCTGCTAGTCCTTAGAGTGTGTGTGTGAAGATGCCATGAC CAGTGGCAGCTGAGACCTCTCTGCCCCAAGAGTGTGGGGGACTGGCAGGGAGCGAGGGTCCCCGAGACGAGGACCACGGTCCTCCCTGAG AACCTGGGTGGAACTGGCATTTCATCCCCTCTCCACCCTACCCTCTGGCTCCTAGCCCACACCCCCTCTCTTGGGCAGCGTGGTCTGCTG GCTGCCCCTTCTTGGCAGCTCAGGGTCGTGGCAGGTGGACTTGGAGACACACAGCAGTGTGTGTTTTAGTGGCAGGTTTCAGGAGCACCT CTAAGACCAGGGTGACAGGGTACTTGGGAGCTGTCCTGGACCCTCCCCATACCACGGGCCCTGCAAGGGAGGCATCAGGGCTGGCTTTGT TTTCTGCTGTTCTTGGAATAGGAACTGCTGTTCTGATCCCCCCAAAACTGCATTGCGGCTCTCGCTCGCTCCTGCCTGCCGGGACAGCGC CTTCTGCTGAGTCCGTTTATTTGTAGTGTCATGGCTGCTGCTTTCACTGGGGTCCTGGGCACCCTGGCTTCTGTCCTCAGAGCTGGGTTT GATCCTAGCAACCATCCCTTCCTCTCTTTGCCCGGCAATGCCTTTGGCATGTGTCTGAGCAGCCAAGTGGCCACTCATAGGAGAAGGCTC CCTGGTCACGTTGCTCCTGCTGCCGTCTTGTTCCAAGGTGCGGGGGGGACACTGTTGGTCTGTCCAGGTCAAGGTCCCTTTCTCTTACCA TGACAGAGGCTGGGGGCAGACAGCGGGGACTTTTTTTTTTTTTTAAGAAAAACTACATGTACATAGGAGAGTTTCATTACCATTAGACTT GTATGTAGGACTTAAAAAAAAATGGCCTTAATAAAATTACAAGCAACCCGCCTGGATGCGGTTTTCAAAAGAAGGCATTGAGGACCATGC TAGGAAACCTCATACCCCATCCGTCCAACCTCCGGCGGGCGCCACTGCTTGTCCTCTGGTCTTCGGTGTGGACAGATAGGAGAGGAGGGA TGCCCACCTCGGAGCATCCCAGGCCCGTGGCCCATTTTCAGCATCCTGAAGCCAGATTCACAGTGACATTGTGTTAACGTGACGACCTTG GTCCATTATGGAGTTCTTTTTCCAATAAGAACCTGGTGGACCGAGGTCCGAGCTTGCCAGGGACAGTGGGGCCCACGCGAGTACCCGGGG CCCAGCCAGGAGCCAGCAGCCAGGCGTCCCTGTGTTCCAGAAGGATTCACGCCCCTCCTGGACCTGGGCGGGCCTCCCAGGGGGTCTGTA TCACGGCCTTTTGTGTGTGCGTACGTGTGGTTTTTTTAAATATCACTACTACATATTCTTGAATTGCCAAGACTTTCTGAAACAAGACAG CTTAAGGGAATCAGCCTTTTGCTTTGTGATGTGAAAATACTGTGATTTGACGAGCCGCTTCCTGAGGGGCAGGCCCACGTGGGGAGGTTG CGCCGTGTACATAGACCCGCCGTCTGTGTCCTTGGTCAGGCCCGGATGCTTGGTCTACACTGGGTTAGAGGCTGCTCTCCCCACGCACCC ATGTGCTCATGGCTTCTGCAGACCCTCTGCTGGGTACATCGGTCCCCTACGGCGAAGTTCAGCCAGGGCTCTCCCTCCTGAGAGCATGGC GTCCCCACCTTCCTGTTTCGCCGACGTCACTACCCAGGGTGGCAAGTCTTGCAGGCAGAGGGTGTAGCCCAAGTTCAGCCTCTCTCTGTG TCCTCCAGAGAAGAGGGTTCTTTGCCCTCATCAGGGCCCTGCTTGTGGGTTTTCGGCTCTGGGGAGGAGAGTGTTGGCATCAGTGTGTTT GGCCTGATTTCTTCAGGGGGCCAAGCTCCCGGGAGGACCCCTAGCCAGGAGGGCCCCCCATGTCCATCCATCCCTCCTGCTGGGGCTTGG ATGTCAGGCTTGGGGGCTGTGAGCTGGGACCTCGCCTGAGCCCGGTCAGGTGGGACAGGAGCCTGCCAGAAGCCCATGGGGGGCCAGGCC GGGTGGCTTCTATTTTATTTTTTTAGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGTCTCGGACTCCTGGGCTCAAGCAGTCCTCCCTC CTCGGCCTCCCAAAGTTCTGGGGCTACAGGTGTGAGCCACTTCTGCCCAGCATCCCAGGCCTGAACAGCCTTGGCAGGACCCGTCCCTAG AGGGGGCTCTGGTGCCTCCCTTAGGTGGGCCTTGAGCTGGTTTTTAACCAAACATCCTTCCAAACTCGGGCTGCGACCTGCTTCCTGAGT TTTCTGTATTTCCAAGGAGCCCTCCGACCAGGGAGAGGCTGGTGGAGTAAGGTCCAGCGGTATTCGGGGGTCCTCTGTCACCTCGCCCTG AAAACAGCAGCTCCCATCACCTTCACTGGGTCCCGATGGAGCCGTCTCAGAGGCCGAGGGGCCCTCTGTGTGGGGGTGGGACGCAGGGGC TCTCAGAGCAAGGGCCACAAAGCCGATGGCACAGATGTGCCCCTGGGCCTGGCCCGTCACCCACATGTGGTGCCCTGGGCCAGGGCGTGC GGGCGCCAGAGCCTTCCCTACACAGCCTAAGAGCAGGGGCAAGACTCGGCCCCTCACTCACCCTGGGAGGCCTGCCTGGGCTACATGGAC ACCTGGGTCTCTTTCTACCCCCATTCACCATGGACCAGGGGCCTCCATTTCCTGGGGGCTCTTGCGGCATGTGATTTGGGGGTCCCTGGG ACATTCTCCCGTCAGCTCCACCTGAGCCAAGTGTCCTGTTCCCTGCGGCCCTTGGCCTTCCAGGGTCCTGGCCAGGCAGGGGTCAGGCAC CCCATACTCTTCCGTGTGGCACAGGTGTCCACCCACCCCCACTGGCCACAGACACCATTCTCCCCCTGGGAGCAGGAGGTGGAGTAAGTT GTACCCCCAGGCCTGGGTGCTGGGGAGTTCCTGAGGGCATGGGTGGGGCAGGAGTGAGTGCCTCGTGATCCCAGCCTCAGTTTCTCTCTT GTCACTTTCTCAAACCTGCAGGTCTCAGGGCCCCGGGCTCCTCCTGGGCAGGATGGGGGGCAGGGGCTGGGCCTTGGGGTGGTGCTGGCT CTGATGATTCCAGAGCCTGTATCCACCTTCTGGGCTCCTGGCCAGCACCCCACCCCCAGGAGCCAGGGACAGGTGGCATGTGTTGGGGTC GGGGGATGGCCCCCATCTCGAAGTGTTCTGGAATTTGGGGGCAACCCTTGCCCAGCCCAGCCATCAAGAACTTCTGATCTCCTGCCCACC AGGAGGGGACTTAGCCATGGACTTGGCCAGTAGGCCTGGGGAGGGAGGGCTTTGGCAGCCAAAGTCCACTGGCCCTGCCGTGCCCCTGAG TAGGAAACTGTCCCCTAGGGGCTGGGTGGCCCCACTGATATATGCAAACCCGCCGGTCCGAGCCCTGTTCCTGCCTGTGCTCCTCTGTGC >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000594658_chr19_18853719_+_4147nt CTCCCTCTCCTATCGGAGCACAATGAAAGCCTGTGTATCGCCGTGACTCCGGGCGCGAGCCAGTGTCAGCAAAGCGGCTAACAACAGACG AGAAAGAGAAAGGAAAATACAAGCTACTTTTTTTTTCCATCTATAAAGCGGAGCAAATACAGGAGATAGAACCAGATTGCTTATTGCGAG TCCAGACCCTCAGATCCACTGGCCGGGGATGGAATGTACAAAAGTGGACAGAAAAGTGGCTGGACATGACTCGGTGCAATTTGCTGGAAG TTTGTAAGTTTGACCATCGTTTGTAAATTACTCTCGGAAGAGTTTGTCTCTCTTGATACTGTATTAGAATAGAGCCGGGGGTGAGGAATA GAAACGTAAGCGGGAAAGAAAAAAATGTGTTGAAGGATCTCTCTCAGTGGCTAGCGACTTAAGATTGCTTTTCATTTAAGGCTAGGAAAC CTTAGAGGGAGTGAGGATTTTACCGGTGATTGGATTAGCTGAAGAAAAAAGCATGGTCCAAAAGTCCAATTACTGACATTGTTAACAGTT GAAAAGCTGTCTCCCTCTTTTGGGAGAAGACAACATCCTACAGTACCCCAAAGAGGAGAAAACACCGGAGCGAAAGGAAAGGGAGGAAAA ATTAAAAGCCAAAAGACAGTCTCCCTTGATTTTTGCACATTTTGAACAGTGACTTAAACATCTTCTGAAACAGCACTGTTTTGTTTTGTT TTGGTTTTTTATTTAACCTGAGGAAAAGTCAAGGCTGCTGGTTACATAGACATGGTAGAAATGTGTTTCTCTGCAGAAACATCCCCATAA AGAATTGTCGGAAACAACTAGGTGAGGGGGAGTCCTCTCTATTAATACCTCTCTCAATACCTTTTGCTGTGTGTTTCTGTCTCTTGCTGG ACAATCCCTGAATTCTTGATCTAACCCCCAGATCGTGTGTTTACAAAGTACCTAGTGGCTCTTGTCAGCTTGGTGGAGGAAAAAAAATCC ACCAACTCTGTCCAACTTCTCCAGAGCTGTCAAATGCAATTAGAGTAAGTTAATCAGGGTTTGTTTCCAACTTATCCTCCCCCCAGTTGG TTTCTATTCTTTCTCCCCACCCTCTTTTTACTAACTCCCCTCCCCCACAACTTCTCCACGGCTCCCCCACAACCTCTGAAGACCTCTATT CATGTGGCCCTGAACACTGAGCTCACATTGTCAAAAACAGACTTGCCTGCAATAGCCAGCAGTAGCCTCTTTCCACCTCACCATCCCAGA GGCAGCAATCATTGTGTCCGGTAAGATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCT CCTTGGAGGGGGCTCAGTCACCCCGAGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCT GAGCTGTGAAGGACGATATGAACGAGGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCA TGGCCAGGGGGCAAGGAAAGCTGGCAAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCC TCCTGCGGCCTCCCAAGCAGCAGCAACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAG CAATAATGGTGGCAGTGGTGGGATAAACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCT CCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAG TGGCACCATGGACCTGCCCTTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAG GGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTA TGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCAC GCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATC AGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACAT CTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCA CTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGC CAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCC CCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGC CCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCC TCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAG CCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATC GATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGT CTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGAT GGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCC GGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGC CAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGG GGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCT CAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCG CTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAAT GCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACC CGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCG GGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGG GCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAG CCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCCAGAGCGCGGGGCAGACGCAAAGTGAAATAAACACTATTT >In-frame_MAML2_ENST00000524717_chr11_96074547_-_CRTC1_ENST00000601916_chr19_18853719_+_3632nt CTCCCTCTCCTATCGGAGCACAATGAAAGCCTGTGTATCGCCGTGACTCCGGGCGCGAGCCAGTGTCAGCAAAGCGGCTAACAACAGACG AGAAAGAGAAAGGAAAATACAAGCTACTTTTTTTTTCCATCTATAAAGCGGAGCAAATACAGGAGATAGAACCAGATTGCTTATTGCGAG TCCAGACCCTCAGATCCACTGGCCGGGGATGGAATGTACAAAAGTGGACAGAAAAGTGGCTGGACATGACTCGGTGCAATTTGCTGGAAG TTTGTAAGTTTGACCATCGTTTGTAAATTACTCTCGGAAGAGTTTGTCTCTCTTGATACTGTATTAGAATAGAGCCGGGGGTGAGGAATA GAAACGTAAGCGGGAAAGAAAAAAATGTGTTGAAGGATCTCTCTCAGTGGCTAGCGACTTAAGATTGCTTTTCATTTAAGGCTAGGAAAC CTTAGAGGGAGTGAGGATTTTACCGGTGATTGGATTAGCTGAAGAAAAAAGCATGGTCCAAAAGTCCAATTACTGACATTGTTAACAGTT GAAAAGCTGTCTCCCTCTTTTGGGAGAAGACAACATCCTACAGTACCCCAAAGAGGAGAAAACACCGGAGCGAAAGGAAAGGGAGGAAAA ATTAAAAGCCAAAAGACAGTCTCCCTTGATTTTTGCACATTTTGAACAGTGACTTAAACATCTTCTGAAACAGCACTGTTTTGTTTTGTT TTGGTTTTTTATTTAACCTGAGGAAAAGTCAAGGCTGCTGGTTACATAGACATGGTAGAAATGTGTTTCTCTGCAGAAACATCCCCATAA AGAATTGTCGGAAACAACTAGGTGAGGGGGAGTCCTCTCTATTAATACCTCTCTCAATACCTTTTGCTGTGTGTTTCTGTCTCTTGCTGG ACAATCCCTGAATTCTTGATCTAACCCCCAGATCGTGTGTTTACAAAGTACCTAGTGGCTCTTGTCAGCTTGGTGGAGGAAAAAAAATCC ACCAACTCTGTCCAACTTCTCCAGAGCTGTCAAATGCAATTAGAGTAAGTTAATCAGGGTTTGTTTCCAACTTATCCTCCCCCCAGTTGG TTTCTATTCTTTCTCCCCACCCTCTTTTTACTAACTCCCCTCCCCCACAACTTCTCCACGGCTCCCCCACAACCTCTGAAGACCTCTATT CATGTGGCCCTGAACACTGAGCTCACATTGTCAAAAACAGACTTGCCTGCAATAGCCAGCAGTAGCCTCTTTCCACCTCACCATCCCAGA GGCAGCAATCATTGTGTCCGGTAAGATGGGGGACACAGCGCCCCCGCAGGCCCCCGCAGGAGGGCTAGGGGGGGCCTCTGGGGCGGGGCT CCTTGGAGGGGGCTCAGTCACCCCGAGAGTGCACAGTGCTATCGTGGAGCGCCTCCGGGCTCGGATCGCTGTCTGCCGCCAACACCACCT GAGCTGTGAAGGACGATATGAACGAGGTAGGGCCGAGAGCTCAGACCGGGAAAGAGAAAGCACCTTGCAGCTCCTGAGCCTTGTACAGCA TGGCCAGGGGGCAAGGAAAGCTGGCAAACACACCAAGGCCACCGCCACTGCTGCCACCACTACAGCCCCTCCACCGCCCCCTGCTGCCCC TCCTGCGGCCTCCCAAGCAGCAGCAACAGCAGCCCCACCGCCCCCACCAGACTATCACCATCACCACCAGCAGCACCTGCTGAACAGTAG CAATAATGGTGGCAGTGGTGGGATAAACGGAGAGCAGCAGCCGCCCGCTTCAACCCCAGGGGACCAGAGGAACTCAGCCCTGATTGCGCT CCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAG TGGCACCATGGACCTGCCCTTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAG GGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTA TGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCAC GCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATC AGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACAT CTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCA CTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGC CAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCC CCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGCTGGAGCAGTTCAACAT GATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAG CCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCC CCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACT CAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCG GATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTC CCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAA GCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTG CAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGG CGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCACTGCCTT CCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCC |
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FusionGenePPI for MAML2_CRTC1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MAML2 | MAML1, NOTCH1, DIABLO, CREBBP, EP300, RBPJ | CRTC1 | CREB1, MAP3K1, MEIS1, YWHAE, CREBBP, EP300, SRPK2, XPO1, KCTD3, KIF13B, CBY1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MAML2_CRTC1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MAML2_CRTC1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MAML2 | C3495559 | Juvenile arthritis | 1 | CTD_human |
| Tgene | CRTC1 | C0279628 | Adenocarcinoma Of Esophagus | 1 | CTD_human |
| Tgene | CRTC1 | C0525045 | Mood Disorders | 1 | PSYGENET |
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