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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 20579

FusionGeneSummary for MAGI1_SUCLG2

check button Fusion gene summary
Fusion gene informationFusion gene name: MAGI1_SUCLG2
Fusion gene ID: 20579
HgeneTgene
Gene symbol

MAGI1

SUCLG2

Gene ID

154043

8801

Gene nameCNKSR family member 3succinate-CoA ligase GDP-forming beta subunit
SynonymsCNK3|CNK3/IPCEF1|MAGI1G-SCS|GBETA|GTPSCS
Cytomap

6q25.2

3p14.1

Type of geneprotein-codingprotein-coding
Descriptionconnector enhancer of kinase suppressor of ras 3CNK homolog protein 3connector enhancer of KSR 3maguin-like proteinmembrane associated guanylate kinase, WW and PDZ domain containing 1membrane-associated guanylate kinase-interacting protein-like 1succinate--CoA ligase [GDP-forming] subunit beta, mitochondrialGTP-specific succinyl-CoA synthetase beta subunitGTP-specific succinyl-CoA synthetase subunit betaSCS-betaGsuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialsuccinyl-CoA ligase
Modification date2018052220180522
UniProtAcc

Q96QZ7

Q96I99

Ensembl transtripts involved in fusion geneENST00000330909, ENST00000402939, 
ENST00000483466, ENST00000497477, 
ENST00000470990, 		ENST00000493112, 
ENST00000307227, ENST00000492795, 
Fusion gene scores* DoF score10 X 6 X 6=3604 X 2 X 3=24
# samples 104
** MAII scorelog2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MAGI1 [Title/Abstract] AND SUCLG2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPRADTCGA-ZG-A9KY-01AMAGI1chr3

66023671

-SUCLG2chr3

67451275

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000330909ENST00000493112MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000330909ENST00000307227MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
5CDS-intronENST00000330909ENST00000492795MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000402939ENST00000493112MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000402939ENST00000307227MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
5CDS-intronENST00000402939ENST00000492795MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000483466ENST00000493112MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000483466ENST00000307227MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
5CDS-intronENST00000483466ENST00000492795MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000497477ENST00000493112MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
In-frameENST00000497477ENST00000307227MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
5CDS-intronENST00000497477ENST00000492795MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
intron-3CDSENST00000470990ENST00000493112MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
intron-3CDSENST00000470990ENST00000307227MAGI1chr3

66023671

-SUCLG2chr3

67451275

-
intron-intronENST00000470990ENST00000492795MAGI1chr3

66023671

-SUCLG2chr3

67451275

-

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FusionProtFeatures for MAGI1_SUCLG2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAGI1

Q96QZ7

SUCLG2

Q96I99

May play a role as scaffolding protein at cell-celljunctions. May regulate acid-induced ASIC3 currents by modulatingits expression at the cell surface (By similarity). {ECO:0000250}. GTP-specific succinyl-CoA synthetase functions in thecitric acid cycle (TCA), coupling the hydrolysis of succinyl-CoAto the synthesis of GTP and thus represents the only step ofsubstrate-level phosphorylation in the TCA. The beta subunitprovides nucleotide specificity of the enzyme and binds thesubstrate succinate, while the binding sites for coenzyme A andphosphate are found in the alpha subunit. {ECO:0000255|HAMAP-Rule:MF_03221}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-12517_1051041288DomainPDZ 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-12317_1051041463DomainPDZ 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-12317_1051041257DomainPDZ 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-12117_1051041161DomainPDZ 1
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000307227-811365_367354433RegionSubstrate binding%3B shared with subunit alpha
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000493112-811365_367354441RegionSubstrate binding%3B shared with subunit alpha

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-1251341_13441041288Compositional biasNote=Poly-Ala
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-1251398_14011041288Compositional biasNote=Poly-Arg
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125402_4211041288Compositional biasNote=Poly-Gln
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125662_6651041288Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125978_9881041288Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-1231341_13441041463Compositional biasNote=Poly-Ala
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-1231398_14011041463Compositional biasNote=Poly-Arg
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123402_4211041463Compositional biasNote=Poly-Gln
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123662_6651041463Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123978_9881041463Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-1231341_13441041257Compositional biasNote=Poly-Ala
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-1231398_14011041257Compositional biasNote=Poly-Arg
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123402_4211041257Compositional biasNote=Poly-Gln
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123662_6651041257Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123978_9881041257Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-1211341_13441041161Compositional biasNote=Poly-Ala
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-1211398_14011041161Compositional biasNote=Poly-Arg
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121402_4211041161Compositional biasNote=Poly-Gln
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121662_6651041161Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121978_9881041161Compositional biasNote=Poly-Gly
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-1251124_12061041288DomainPDZ 6
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125300_3331041288DomainWW 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125359_3921041288DomainWW 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125472_5541041288DomainPDZ 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125643_7211041288DomainPDZ 3
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125813_8951041288DomainPDZ 4
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-12596_2871041288DomainGuanylate kinase-like
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-1231124_12061041463DomainPDZ 6
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123300_3331041463DomainWW 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123359_3921041463DomainWW 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123472_5541041463DomainPDZ 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123643_7211041463DomainPDZ 3
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123813_8951041463DomainPDZ 4
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-12396_2871041463DomainGuanylate kinase-like
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-1231124_12061041257DomainPDZ 6
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123300_3331041257DomainWW 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123359_3921041257DomainWW 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123472_5541041257DomainPDZ 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123643_7211041257DomainPDZ 3
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123813_8951041257DomainPDZ 4
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-12396_2871041257DomainGuanylate kinase-like
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-1211124_12061041161DomainPDZ 6
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121300_3331041161DomainWW 1
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121359_3921041161DomainWW 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121472_5541041161DomainPDZ 2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121643_7211041161DomainPDZ 3
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121813_8951041161DomainPDZ 4
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-12196_2871041161DomainGuanylate kinase-like
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125103_1101041288Nucleotide bindingATP
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123103_1101041463Nucleotide bindingATP
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123103_1101041257Nucleotide bindingATP
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121103_1101041161Nucleotide bindingATP
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000307227-81146_274354433DomainATP-grasp
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000493112-81146_274354441DomainATP-grasp
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000307227-81190_92354433Nucleotide bindingGTP
TgeneSUCLG2chr3:66023671chr3:67451275ENST00000493112-81190_92354441Nucleotide bindingGTP


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FusionGeneSequence for MAGI1_SUCLG2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_191aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRYFYGKKRKLYAHKTRNRKFKXEYNWYPRERRPPKS

>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_183aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRNQRPRGPEDTQQQRTPHYFSHXPGGCSQEGCGQCG

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_191aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRYFYGKKRKLYAHKTRNRKFKXEYNWYPRERRPPKS

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_183aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRNQRPRGPEDTQQQRTPHYFSHXPGGCSQEGCGQCG

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_191aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRYFYGKKRKLYAHKTRNRKFKXEYNWYPRERRPPKS

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_183aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRNQRPRGPEDTQQQRTPHYFSHXPGGCSQEGCGQCG

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_191aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRYFYGKKRKLYAHKTRNRKFKXEYNWYPRERRPPKS

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_183aa
MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVI
DSCKEAVTFKAVRQGXSHPCQYIWWYRQLCHHCQWDHQSLPGARTQGAPGGPAXRNQRPRGPEDTQQQRTPHYFSHXPGGCSQEGCGQCG


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_574nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT

>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_550nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_574nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_550nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_574nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_550nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_574nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_550nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_743nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT
GAGTAAGTGTGCCATCAGCATTTTTTTATGTTAAAGATTTACTTTGCTAAGATACTTGCTGAGATTACTTTTCCAAATTAATGAATATCA
TCACAAAATTATTTTTTTACATTTGGGTTCAGCTGCATGCTAATGGAAATGGAAAATGGAAGGGCATGGCTTATAGCTGTTCATTCACCA

>In-frame_MAGI1_ENST00000330909_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_1575nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC
CAAGAAGTGATGTCTTTGTCCTGATCCAATGGAGAAAGAAAGCCATTTTTCCGTAAAAAGGGATGGTTCATCATTGTGAAAGAAATGGTT
ATCTCATTGGGGAAGAAAAGGGGAGGGGGAAGGCAAGAATCACTGAAAAATCTTAAATCTGTGTTTTCTGGAATAAGATATCTAGACAGC
CTAAATCTGATTTTGGTCTTTATAAAAATAATATCTTGTGTTCTCATACTTTTCTGTCACTGTAAGCCTGCCCAGTAGGCAGTGTTTTGC
AGACTTTGGGGAGTGGTCTATGTGGCCAAATATTGTGTGTATAGACAGAATTTGAAATCAAGTCCTGCTTCATTTACAAGAATTTTGGTG
GGCATCTAATCCTACATAATGAAAAAGAAAAACAGACCATTTAAAAACTCAGACAAGATTATATTTAATATATTAATTACTAAAAAGGCA
TAAGATTACACTGAACATATTAGCTACTAAAAAGGCACTGCTAAGACATTCAAGCAAATAGCTATTACACACTACTGCAGATTTTACAGG
TTTCTAATTCTAACATATGTTTGAAAAATCCGTGAGTATTCCAAAATATATTTAATAATGGAATATCTGCATTAATATACCATCCATGTG
TTTTTACCATTTGCCTTAATATTGAATATACTGTTTACCTCACACTAAAAAGAAAACCAGAAGCCTTATTTGTGATTTTGGGAGTGGAAG
CTTCCATTTTTGTGTCAAAAATGAATCCTGATTCTTATGGAAATCTCTGTTATTAAGATATTTCAAGATGAGACAACACTGAAGATCAAA
TTGTGTTTAGTATCACTATCTTCTCTCCTCGTTTCTCTCTTACTCCTCATCCTCCCAGAATCTACCAGTTTATGGTAGAAAGATGGGAAC
CTTATTTGAATGTGTTTTTTTTTTCCATGATGTCCAATTTTGTTGTGGGAAAGGATTTGGATAAAATTTTTGTTTAAATTTTGGTAGATT

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_743nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT
GAGTAAGTGTGCCATCAGCATTTTTTTATGTTAAAGATTTACTTTGCTAAGATACTTGCTGAGATTACTTTTCCAAATTAATGAATATCA
TCACAAAATTATTTTTTTACATTTGGGTTCAGCTGCATGCTAATGGAAATGGAAAATGGAAGGGCATGGCTTATAGCTGTTCATTCACCA

>In-frame_MAGI1_ENST00000402939_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_1575nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC
CAAGAAGTGATGTCTTTGTCCTGATCCAATGGAGAAAGAAAGCCATTTTTCCGTAAAAAGGGATGGTTCATCATTGTGAAAGAAATGGTT
ATCTCATTGGGGAAGAAAAGGGGAGGGGGAAGGCAAGAATCACTGAAAAATCTTAAATCTGTGTTTTCTGGAATAAGATATCTAGACAGC
CTAAATCTGATTTTGGTCTTTATAAAAATAATATCTTGTGTTCTCATACTTTTCTGTCACTGTAAGCCTGCCCAGTAGGCAGTGTTTTGC
AGACTTTGGGGAGTGGTCTATGTGGCCAAATATTGTGTGTATAGACAGAATTTGAAATCAAGTCCTGCTTCATTTACAAGAATTTTGGTG
GGCATCTAATCCTACATAATGAAAAAGAAAAACAGACCATTTAAAAACTCAGACAAGATTATATTTAATATATTAATTACTAAAAAGGCA
TAAGATTACACTGAACATATTAGCTACTAAAAAGGCACTGCTAAGACATTCAAGCAAATAGCTATTACACACTACTGCAGATTTTACAGG
TTTCTAATTCTAACATATGTTTGAAAAATCCGTGAGTATTCCAAAATATATTTAATAATGGAATATCTGCATTAATATACCATCCATGTG
TTTTTACCATTTGCCTTAATATTGAATATACTGTTTACCTCACACTAAAAAGAAAACCAGAAGCCTTATTTGTGATTTTGGGAGTGGAAG
CTTCCATTTTTGTGTCAAAAATGAATCCTGATTCTTATGGAAATCTCTGTTATTAAGATATTTCAAGATGAGACAACACTGAAGATCAAA
TTGTGTTTAGTATCACTATCTTCTCTCCTCGTTTCTCTCTTACTCCTCATCCTCCCAGAATCTACCAGTTTATGGTAGAAAGATGGGAAC
CTTATTTGAATGTGTTTTTTTTTTCCATGATGTCCAATTTTGTTGTGGGAAAGGATTTGGATAAAATTTTTGTTTAAATTTTGGTAGATT

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_985nt
CGGAATGCAAACAAAGCTCGCGGGCGCCTGTGCGGGGCTCGCGGGGAAGCCCAGAAAGTTTGTTTTATGATGGCTTGAGTGCGCGAGCGT
GTGCAGGGGAGCGAGGCTGCCAAGTTTCTCTCTCCTGTTTTGTGATTTGGGGAGAGATGTTTCTCCCATGAACAAGCGGAGGCTTGGGGG
CTCGTGCTGTGGGGGGCACCTGTCTCTCGTTTTATTTTTTTGGAGGAGGGGTGTAACTCATCATGTCCAAAGTGATCCAGAAGAAGAACC
ACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTGACGGTGCTGGGAGGCGCGGAGCACGGGG
AGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAGGGCCCGAGGCTGGGCGAAGGGGAGCTGC
TTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATCGACAGCTGCAAGGAGGCCGTCACCTTCA
AGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGCCATCATTGCCAATGGGATCACCAAAGCC
TGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAAAAAAGGAAGTTATATGCACATAAAACAA
GAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCTGAGTAAGTGTGCCATCAGCATTTTTTTA
TGTTAAAGATTTACTTTGCTAAGATACTTGCTGAGATTACTTTTCCAAATTAATGAATATCATCACAAAATTATTTTTTTACATTTGGGT

>In-frame_MAGI1_ENST00000483466_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_1817nt
CGGAATGCAAACAAAGCTCGCGGGCGCCTGTGCGGGGCTCGCGGGGAAGCCCAGAAAGTTTGTTTTATGATGGCTTGAGTGCGCGAGCGT
GTGCAGGGGAGCGAGGCTGCCAAGTTTCTCTCTCCTGTTTTGTGATTTGGGGAGAGATGTTTCTCCCATGAACAAGCGGAGGCTTGGGGG
CTCGTGCTGTGGGGGGCACCTGTCTCTCGTTTTATTTTTTTGGAGGAGGGGTGTAACTCATCATGTCCAAAGTGATCCAGAAGAAGAACC
ACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTGACGGTGCTGGGAGGCGCGGAGCACGGGG
AGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAGGGCCCGAGGCTGGGCGAAGGGGAGCTGC
TTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATCGACAGCTGCAAGGAGGCCGTCACCTTCA
AGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGCCATCATTGCCAATGGGATCACCAAAGCC
TGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGAGGCCCAGAAGATACTCAACAACAGCGGA
CTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGCCAAGAAGTGATGTCTTTGTCCTGATCCA
ATGGAGAAAGAAAGCCATTTTTCCGTAAAAAGGGATGGTTCATCATTGTGAAAGAAATGGTTATCTCATTGGGGAAGAAAAGGGGAGGGG
GAAGGCAAGAATCACTGAAAAATCTTAAATCTGTGTTTTCTGGAATAAGATATCTAGACAGCCTAAATCTGATTTTGGTCTTTATAAAAA
TAATATCTTGTGTTCTCATACTTTTCTGTCACTGTAAGCCTGCCCAGTAGGCAGTGTTTTGCAGACTTTGGGGAGTGGTCTATGTGGCCA
AATATTGTGTGTATAGACAGAATTTGAAATCAAGTCCTGCTTCATTTACAAGAATTTTGGTGGGCATCTAATCCTACATAATGAAAAAGA
AAAACAGACCATTTAAAAACTCAGACAAGATTATATTTAATATATTAATTACTAAAAAGGCATAAGATTACACTGAACATATTAGCTACT
AAAAAGGCACTGCTAAGACATTCAAGCAAATAGCTATTACACACTACTGCAGATTTTACAGGTTTCTAATTCTAACATATGTTTGAAAAA
TCCGTGAGTATTCCAAAATATATTTAATAATGGAATATCTGCATTAATATACCATCCATGTGTTTTTACCATTTGCCTTAATATTGAATA
TACTGTTTACCTCACACTAAAAAGAAAACCAGAAGCCTTATTTGTGATTTTGGGAGTGGAAGCTTCCATTTTTGTGTCAAAAATGAATCC
TGATTCTTATGGAAATCTCTGTTATTAAGATATTTCAAGATGAGACAACACTGAAGATCAAATTGTGTTTAGTATCACTATCTTCTCTCC
TCGTTTCTCTCTTACTCCTCATCCTCCCAGAATCTACCAGTTTATGGTAGAAAGATGGGAACCTTATTTGAATGTGTTTTTTTTTTCCAT
GATGTCCAATTTTGTTGTGGGAAAGGATTTGGATAAAATTTTTGTTTAAATTTTGGTAGATTTTTATCTATACAAATTTAAATAAAATTA

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000493112_chr3_67451275_-_743nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGTACTTTTATGGAAAA
AAAAGGAAGTTATATGCACATAAAACAAGAAACAGGAAATTCAAATGAGAATATAACTGGTATCCAAGAGAACGTCGCCCACCAAAATCT
GAGTAAGTGTGCCATCAGCATTTTTTTATGTTAAAGATTTACTTTGCTAAGATACTTGCTGAGATTACTTTTCCAAATTAATGAATATCA
TCACAAAATTATTTTTTTACATTTGGGTTCAGCTGCATGCTAATGGAAATGGAAAATGGAAGGGCATGGCTTATAGCTGTTCATTCACCA

>In-frame_MAGI1_ENST00000497477_chr3_66023671_-_SUCLG2_ENST00000307227_chr3_67451275_-_1575nt
ATGTCCAAAGTGATCCAGAAGAAGAACCACTGGACTAGCAGGGTTCACGAATGCACCGTGAAGCGGGGACCCCAGGGCGAGCTGGGGGTG
ACGGTGCTGGGAGGCGCGGAGCACGGGGAGTTTCCGTACGTCGGAGCGGTGGCGGCGGTCGAGGCAGCGGGGCTTCCCGGCGGCGGCGAG
GGCCCGAGGCTGGGCGAAGGGGAGCTGCTTCTGGAGGTGCAGGGGGTCCGGGTGTCCGGCTTGCCCCGCTATGACGTGCTGGGGGTCATC
GACAGCTGCAAGGAGGCCGTCACCTTCAAGGCCGTCAGACAAGGTTGAAGCCATCCTTGTCAATATATTTGGTGGTATCGTCAACTGTGC
CATCATTGCCAATGGGATCACCAAAGCCTGCCGGGAGCTAGAACTCAAGGTGCCCCTGGTGGTCCGGCTTGAAGGAACCAACGTCCAAGA
GGCCCAGAAGATACTCAACAACAGCGGACTCCCCATTACTTCAGCCATTGACCTGGAGGATGCAGCCAAGAAGGCTGTGGCCAGTGTGGC
CAAGAAGTGATGTCTTTGTCCTGATCCAATGGAGAAAGAAAGCCATTTTTCCGTAAAAAGGGATGGTTCATCATTGTGAAAGAAATGGTT
ATCTCATTGGGGAAGAAAAGGGGAGGGGGAAGGCAAGAATCACTGAAAAATCTTAAATCTGTGTTTTCTGGAATAAGATATCTAGACAGC
CTAAATCTGATTTTGGTCTTTATAAAAATAATATCTTGTGTTCTCATACTTTTCTGTCACTGTAAGCCTGCCCAGTAGGCAGTGTTTTGC
AGACTTTGGGGAGTGGTCTATGTGGCCAAATATTGTGTGTATAGACAGAATTTGAAATCAAGTCCTGCTTCATTTACAAGAATTTTGGTG
GGCATCTAATCCTACATAATGAAAAAGAAAAACAGACCATTTAAAAACTCAGACAAGATTATATTTAATATATTAATTACTAAAAAGGCA
TAAGATTACACTGAACATATTAGCTACTAAAAAGGCACTGCTAAGACATTCAAGCAAATAGCTATTACACACTACTGCAGATTTTACAGG
TTTCTAATTCTAACATATGTTTGAAAAATCCGTGAGTATTCCAAAATATATTTAATAATGGAATATCTGCATTAATATACCATCCATGTG
TTTTTACCATTTGCCTTAATATTGAATATACTGTTTACCTCACACTAAAAAGAAAACCAGAAGCCTTATTTGTGATTTTGGGAGTGGAAG
CTTCCATTTTTGTGTCAAAAATGAATCCTGATTCTTATGGAAATCTCTGTTATTAAGATATTTCAAGATGAGACAACACTGAAGATCAAA
TTGTGTTTAGTATCACTATCTTCTCTCCTCGTTTCTCTCTTACTCCTCATCCTCCCAGAATCTACCAGTTTATGGTAGAAAGATGGGAAC
CTTATTTGAATGTGTTTTTTTTTTCCATGATGTCCAATTTTGTTGTGGGAAAGGATTTGGATAAAATTTTTGTTTAAATTTTGGTAGATT


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FusionGenePPI for MAGI1_SUCLG2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MAGI1CTNNB1, LRP2, ASIC3, BZW1, SFN, FCHSD2, WBP1, WBP2, CDH1, NET1, SYNPO, ACTN4, ATN1, BAI1, RAC1, DDN, SSTR3, IGSF5, LATS1, LATS2, RAPGEF2, MOV10, NXF1, CYYR1, LDLRAD4, PTPN14, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, LRFN1, DENND1A, SH3PXD2A, SRGAP2, EIF4E2, SIPA1L1, LIMA1, TESK2, DCLK1, ZNF638, RTKN, MAST3, SRSF12, PPM1H, SYDE1, DENND4C, AGAP1, CDC25B, CDK16, FAM110B, USP21, MAPKAP1, FAM53C, ANKRD34A, CGN, FAM110A, HDAC4, NF1, TBC1D25, NADK, CBY1, TIAM1, PHLDB2, KIAA1804, RASAL2, CAMSAP2, LPIN3, GAB2, CDC25C, MELK, PLEKHA7, KIF1C, GIGYF2, DEPDC1B, NAV1, DENND4A, MLLT4, STARD13, RPTOR, SH3RF3, PLEKHA5, SH3BP4, HDAC7, EDC3, LARP1, RAB3IP, INPP5ESUCLG2GPR143, USP19, DMWD, CUL3, SUCLG1, SDHA, PRDX6, MRPL12, RNASET2, MRPL50, SCAF4, S100A16, SEPT9, NDUFV2, PITRM1, CTTN, SEC22B, SDHAF2, ECT2, ABCE1, ZNF146, DNAJC12, GALNT11, ACADM, ATP6V1A, CCT3, CCT6A, CTSD, HSP90B1, IDH3A, LDHA, LDHAL6A, RPN1, DLD, ETFA, OGDH, PEF1, RAB2A, AK1, FAF2, SLC25A15


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMAGI1chr3:66023671chr3:67451275ENST00000330909-125970_10661041288FCHSD2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000402939-123970_10661041463FCHSD2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000483466-123970_10661041257FCHSD2
HgeneMAGI1chr3:66023671chr3:67451275ENST00000497477-121970_10661041161FCHSD2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MAGI1_SUCLG2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MAGI1_SUCLG2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMAGI1C0005586Bipolar Disorder2PSYGENET
HgeneMAGI1C0010606Adenoid Cystic Carcinoma1CTD_human
HgeneMAGI1C0036341Schizophrenia1PSYGENET
HgeneMAGI1C1839839MAJOR AFFECTIVE DISORDER 21PSYGENET
TgeneSUCLG2C0014175Endometriosis1CTD_human
TgeneSUCLG2C0028754Obesity1CTD_human
TgeneSUCLG2C0268583Methylmalonic acidemia1CTD_human