|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 20528 |
FusionGeneSummary for MACROD2_DCLK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MACROD2_DCLK2 | Fusion gene ID: 20528 | Hgene | Tgene | Gene symbol | MACROD2 | DCLK2 | Gene ID | 140733 | 166614 |
| Gene name | MACRO domain containing 2 | doublecortin like kinase 2 | |
| Synonyms | C20orf133|C2orf133 | CL2|CLICK-II|CLICK2|CLIK2|DCAMKL2|DCDC3|DCDC3B|DCK2 | |
| Cytomap | 20p12.1 | 4q31.23-q31.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | O-acetyl-ADP-ribose deacetylase MACROD2MACRO domain-containing protein 2[Protein ADP-ribosylglutamate] hydrolase | serine/threonine-protein kinase DCLK2CaMK-like CREB regulatory kinase 2doublecortin and CaM kinase-like 2doublecortin domain-containing protein 3Bdoublecortin-like and CAM kinase-like 2 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | A1Z1Q3 | Q8N568 | |
| Ensembl transtripts involved in fusion gene | ENST00000217246, ENST00000310348, ENST00000464883, ENST00000402914, ENST00000378058, ENST00000407045, | ENST00000296550, ENST00000506325, ENST00000302176, ENST00000507694, | |
| Fusion gene scores | * DoF score | 10 X 10 X 8=800 | 2 X 1 X 2=4 |
| # samples | 11 | 2 | |
| ** MAII score | log2(11/800*10)=-2.86249647625006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: MACROD2 [Title/Abstract] AND DCLK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MACROD2 | GO:0042278 | purine nucleoside metabolic process | 21257746 |
| Hgene | MACROD2 | GO:0051725 | protein de-ADP-ribosylation | 23474712 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-C8-A1HN-01A | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000217246 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| In-frame | ENST00000217246 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| In-frame | ENST00000217246 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| 5CDS-intron | ENST00000217246 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| In-frame | ENST00000310348 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| In-frame | ENST00000310348 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| In-frame | ENST00000310348 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| 5CDS-intron | ENST00000310348 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000464883 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000464883 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000464883 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-intron | ENST00000464883 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000402914 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000402914 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000402914 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-intron | ENST00000402914 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000378058 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000378058 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000378058 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-intron | ENST00000378058 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000407045 | ENST00000296550 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000407045 | ENST00000506325 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-3CDS | ENST00000407045 | ENST00000302176 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
| intron-intron | ENST00000407045 | ENST00000507694 | MACROD2 | chr20 | 13983050 | + | DCLK2 | chr4 | 151023630 | + |
Top |
FusionProtFeatures for MACROD2_DCLK2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MACROD2 | DCLK2 |
| Removes ADP-ribose from glutamate residues in proteinsbearing a single ADP-ribose moiety. Inactive towards proteinsbearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, asignaling molecule generated by the deacetylation of acetylatedlysine residues in histones and other proteins.{ECO:0000269|PubMed:21257746, ECO:0000269|PubMed:23474712}. | Protein kinase with a significantly reduced C(a2+)/CAMaffinity and dependence compared to other members of the CaMKfamily. May play a role in the down-regulation of CRE-dependentgene activation probably by phosphorylation of the CREBcoactivator CRTC2/TORC2 and the resulting retention of TORC2 inthe cytoplasm (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 6_9 | 54 | 426 | Compositional bias | Note=Poly-Lys |
| Hgene | MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 6_9 | 54 | 449 | Compositional bias | Note=Poly-Lys |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 293_362 | 140 | 767 | Compositional bias | Note=Ser-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 713_753 | 140 | 767 | Compositional bias | Note=Pro-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 293_362 | 140 | 784 | Compositional bias | Note=Ser-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 713_753 | 140 | 784 | Compositional bias | Note=Pro-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 293_362 | 140 | 766 | Compositional bias | Note=Ser-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 713_753 | 140 | 766 | Compositional bias | Note=Pro-rich |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 197_280 | 140 | 767 | Domain | Doublecortin 2 |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 394_651 | 140 | 767 | Domain | Protein kinase |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 197_280 | 140 | 784 | Domain | Doublecortin 2 |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 394_651 | 140 | 784 | Domain | Protein kinase |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 197_280 | 140 | 766 | Domain | Doublecortin 2 |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 394_651 | 140 | 766 | Domain | Protein kinase |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 400_408 | 140 | 767 | Nucleotide binding | ATP |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 400_408 | 140 | 784 | Nucleotide binding | ATP |
| Tgene | >DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 400_408 | 140 | 766 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 247_388 | 54 | 426 | Compositional bias | Note=Glu-rich |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 247_388 | 54 | 449 | Compositional bias | Note=Glu-rich |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 247_388 | 0 | 214 | Compositional bias | Note=Glu-rich |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 6_9 | 0 | 214 | Compositional bias | Note=Poly-Lys |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 247_388 | -154 | 214 | Compositional bias | Note=Glu-rich |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 6_9 | -154 | 214 | Compositional bias | Note=Poly-Lys |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 247_388 | -79 | 99 | Compositional bias | Note=Glu-rich |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 6_9 | -79 | 99 | Compositional bias | Note=Poly-Lys |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 59_240 | 54 | 426 | Domain | Macro |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 59_240 | 54 | 449 | Domain | Macro |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 59_240 | 0 | 214 | Domain | Macro |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 59_240 | -154 | 214 | Domain | Macro |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 59_240 | -79 | 99 | Domain | Macro |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 185_191 | 54 | 426 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 77_79 | 54 | 426 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 90_92 | 54 | 426 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000217246 | + | 2 | 17 | 97_102 | 54 | 426 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 185_191 | 54 | 449 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 77_79 | 54 | 449 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 90_92 | 54 | 449 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000310348 | + | 2 | 18 | 97_102 | 54 | 449 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 185_191 | 0 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 77_79 | 0 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 90_92 | 0 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000378058 | + | 1 | 10 | 97_102 | 0 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 185_191 | -154 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 77_79 | -154 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 90_92 | -154 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000402914 | + | 1 | 14 | 97_102 | -154 | 214 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 185_191 | -79 | 99 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 77_79 | -79 | 99 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 90_92 | -79 | 99 | Region | Note=Substrate binding |
| Hgene | >MACROD2 | chr20:13983050 | chr4:151023630 | ENST00000407045 | + | 1 | 6 | 97_102 | -79 | 99 | Region | Note=Substrate binding |
| Tgene | DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000296550 | + | 0 | 16 | 72_158 | 140 | 767 | Domain | Doublecortin 1 |
| Tgene | DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000302176 | + | 0 | 17 | 72_158 | 140 | 784 | Domain | Doublecortin 1 |
| Tgene | DCLK2 | chr20:13983050 | chr4:151023630 | ENST00000506325 | + | 0 | 16 | 72_158 | 140 | 766 | Domain | Doublecortin 1 |
Top |
FusionGeneSequence for MACROD2_DCLK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_681aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISA HGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRR VKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLG DFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKE LISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGME >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_680aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKISAH GRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRV KHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGD FGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGMEP >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_698aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKSSS SSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAK CCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPE NLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGK LEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEG >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_681aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISA HGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRR VKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLG DFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKE LISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGME >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_680aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKISAH GRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRV KHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGD FGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGMEP >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_698aa MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRA LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVF IACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKSSS SSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAK CCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPE NLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGK LEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_2043nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCT CATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAA TCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACT GGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGA GTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGAT CTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTC CATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGA GACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACT GGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAAT CTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAA TTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCC CAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGG GTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAG CCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCC >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_2040nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGATTTCTGCTCAT GGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCA TCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGA AAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTG AAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTC TTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCAT GGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGAC TTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGC TATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTC CAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTA ATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAG GAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTC TCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCC ATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCAC >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_2094nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTAAAGCGGGGTGGCCAC TACTCCAGTGCCTATTCTACAGCCAAATCCCCAGTTAATGGAACTCCCAGCAGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGT TCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCTCATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAG CTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTC ATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAA TGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATG GAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAG AGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAG AATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATAC ACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTG ATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAG CTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGG TGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTA AAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGG CAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCT GTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGA >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_2043nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCT CATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAA TCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACT GGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGA GTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGAT CTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTC CATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGA GACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACT GGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAAT CTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAA TTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCC CAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGG GTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAG CCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCC >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_2040nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGATTTCTGCTCAT GGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCA TCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGA AAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTG AAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTC TTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCAT GGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGAC TTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGC TATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTC CAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTA ATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAG GAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTC TCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCC ATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCAC >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_2094nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTAAAGCGGGGTGGCCAC TACTCCAGTGCCTATTCTACAGCCAAATCCCCAGTTAATGGAACTCCCAGCAGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGT TCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCTCATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAG CTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTC ATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAA TGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATG GAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAG AGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAG AATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATAC ACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTG ATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAG CTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGG TGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTA AAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGG CAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCT GTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_3648nt GCGTGCGCCCTGGGGCCCAAGTTGGGGCGCGCCGTGGCTAGAACACGGAGAGCGGCGGGCAGTGCAGCCAATGGGAGGCGGCGCTGCCTA GCGGCTGGTAGGCGGTGCCTGCGCGGGTGTTAGGTTAGCGCGAGGCGTGACCTAGTTGACAGGCTCTGAGGTGCTGCTGTGGCGGCGTCC GCGGGGCTGAGGCGGGTGGGAGCCGGAGCCGAGCGCGGGCTGAGGGAGGAGGGCGGCGACTGGAGAGCGGCGAGCGGCGAGCAGCGCAGG ACGCAGAGCCTCTTTCACTTTTTCCCTGCTGAGTGCCCCCTCCCACCCCTCCCACTCCACACACACCCTGTTTGCCCGTGAGCCTGGGGA ACTTGCAGCTTAAAGCCAGCCACCCCCACGGCAACATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTAT TGAAGATGACCTTAGAAGAGAGACGCAAAGAATACCTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGG GCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGTGCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACT GGTCTGTGAACATCAAGGGTGGGACATCCCGAGCGCTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCA AACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTGAAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTG AACAAGTCTTAACAGATATCACCGAAGCCATTAAACTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTT GTCTGCAAGACTTTTTTGGTGATGACGATGTTTTTATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATC ATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCTCGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCA GCAAATCACCAGCTTCAGTTAATGGAACTCCCAGCAGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTC CAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCTCATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAA GTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATT TTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAAC ACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGC TCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCA TGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTG AATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACAC CCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTC TCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCC CCTACTGGGATAACATCACGGACTCTGCCAAGGAATTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAA TCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATA ATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCA AGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAG TCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGAACCTGGCGCCGCCACC GAGACTGAGCCTCCTGCAGACGGGCGAAGCCGCCTGCTGCAGCCCAGGAAGCCAGCCCTCTGCTCGGCCTCGCCGGCCTCCCTGCTGCAG GCCTCCCTCTCTTCACCGCCTGCGCCTGAGTTCGCGGGTCCTCCGCAGGCCGCCTGGGAACCGGAGCCTGGCGTGCCGGAGCCTGGCCTG GTGCTCTGGGCTCTGCCTTCTGGTTCCTGGAGGCATCAAAGGCTGCATCCGTTCTGCCAACAGCTGTTCGGAGAGACTCGTTCCAGATCA TCCCGTCATTTTCAGTTTGTTGGACATTTTACAGCTTCACCAGGAGAATGTGCAACTTTATTCCAGCATTCGATGCATTTTTATAGAAAC ACTTTGGAAACACTTTGGATGAACCAAGGCCTTTTCCTTATTTAAGTAGACTCAGAACACTCCCTTTCTTTTCTTTTCTCTCTCTCTCTC TCTTTTTTTTTTACGAAAGACTTAGAATTGCATTTGTCCTTTTGTGGGTGTCCTGTGAGAGGTGATATGGGGGCTAAGAGGACTGGCTTT CTAATAGAAGAAGTGAGCGCCTGAGAGGACAATTTGGTCATTGGACACGGATTGCAGGCTTTGAGAAGCGCTCAGAGGCCCAGGGCGGCG GGCTCAGCCATTCGGCTTGGGGCACCAGGCTCCCCAGAGACAATGCTCAGTATTCATTCATACACAGACGATGGAAGAAGCCACTTCTTC CCTGGGCGGTGTGGGTTTCCCCCAGCTCTTCCCACACGTGTGTTAGGAAATGCCCGTGAACTTGCCCTCTGGGCTTTTTAATGAGAGGCT TGGCGCATGCGGCACCCAGCGGCTGCTTCCCTGCAAGCCAGCGACTTGCCGAGCAGAATGAGCTCTGCTCCTGAGCCCCGGTAGCTGCTT CCTCATCTGCATTTCATCTGGAGCAGGGCAGGTAACCACAGGAGGAGGCATGCCCGAGGCAGCCAGGACTGGGCGGGAAGGTGCTCCCTG GATATACTCTGTGAACCTTCTGGAAGGCTGCTGGCAGTTTTTCCTTTTTGTCCACCACCCTGCTCTTTTTAATAATTGTACATAATCCGT GTATTTGTTTTACCTGCTCATCTTCTAAACTGGCGAGCCCTATAGTTCGTTCTCATTGTTAGATTTTGCCTTTTACAAGTGTCCCCAACC >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_2435nt GCGTGCGCCCTGGGGCCCAAGTTGGGGCGCGCCGTGGCTAGAACACGGAGAGCGGCGGGCAGTGCAGCCAATGGGAGGCGGCGCTGCCTA GCGGCTGGTAGGCGGTGCCTGCGCGGGTGTTAGGTTAGCGCGAGGCGTGACCTAGTTGACAGGCTCTGAGGTGCTGCTGTGGCGGCGTCC GCGGGGCTGAGGCGGGTGGGAGCCGGAGCCGAGCGCGGGCTGAGGGAGGAGGGCGGCGACTGGAGAGCGGCGAGCGGCGAGCAGCGCAGG ACGCAGAGCCTCTTTCACTTTTTCCCTGCTGAGTGCCCCCTCCCACCCCTCCCACTCCACACACACCCTGTTTGCCCGTGAGCCTGGGGA ACTTGCAGCTTAAAGCCAGCCACCCCCACGGCAACATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTAT TGAAGATGACCTTAGAAGAGAGACGCAAAGAATACCTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGG GCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGTGCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACT GGTCTGTGAACATCAAGGGTGGGACATCCCGAGCGCTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCA AACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTGAAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTG AACAAGTCTTAACAGATATCACCGAAGCCATTAAACTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTT GTCTGCAAGACTTTTTTGGTGATGACGATGTTTTTATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATC ATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCTCGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCA GCAAATCACCAGCTTCAGTTAATGGAACTCCCAGCAGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTC CAGGAAGTTTCAGAGGATTAAAGATTTCTGCTCATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTC CTGAAGGTGTGAATGGAAACAGATGCTCTGAATCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTG CAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACC TGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCT TTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGG TGTACAACTTAGCCAATGCCCTCAGGTATCTCCATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAAT ATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCA CTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCT GTGGATTCCCACCATTCCGAAGTGAGAACAATCTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCT ACTGGGATAACATCACGGACTCTGCCAAGGAATTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCC TGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATG CGCTCCCCAAACAGAACAGCACTACCACCGGGGTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGC ACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCC CGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGAACCTGGCGCCGCCACCGAG >In-frame_MACROD2_ENST00000217246_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_3680nt GCGTGCGCCCTGGGGCCCAAGTTGGGGCGCGCCGTGGCTAGAACACGGAGAGCGGCGGGCAGTGCAGCCAATGGGAGGCGGCGCTGCCTA GCGGCTGGTAGGCGGTGCCTGCGCGGGTGTTAGGTTAGCGCGAGGCGTGACCTAGTTGACAGGCTCTGAGGTGCTGCTGTGGCGGCGTCC GCGGGGCTGAGGCGGGTGGGAGCCGGAGCCGAGCGCGGGCTGAGGGAGGAGGGCGGCGACTGGAGAGCGGCGAGCGGCGAGCAGCGCAGG ACGCAGAGCCTCTTTCACTTTTTCCCTGCTGAGTGCCCCCTCCCACCCCTCCCACTCCACACACACCCTGTTTGCCCGTGAGCCTGGGGA ACTTGCAGCTTAAAGCCAGCCACCCCCACGGCAACATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTAT TGAAGATGACCTTAGAAGAGAGACGCAAAGAATACCTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGG GCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGTGCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACT GGTCTGTGAACATCAAGGGTGGGACATCCCGAGCGCTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCA AACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTGAAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTG AACAAGTCTTAACAGATATCACCGAAGCCATTAAACTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTT GTCTGCAAGACTTTTTTGGTGATGACGATGTTTTTATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATC ATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCTCGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCA GCAAATCACCAGCTTCAGTAAAGCGGGGTGGCCACTACTCCAGTGCCTATTCTACAGCCAAATCCCCAGTTAATGGAACTCCCAGCAGCC AACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCTCATG GCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCAT CAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAA AGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGA AACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCT TTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCATG GCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACT TTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCT ATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTCC AGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTAA TCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGG AGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTCT CCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCA TCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACC CTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGAACCTGGCGCCGCCACCGAGACTGAGCCTCCTGCAGACGGGCGAAGCCGCCTGCTG CAGCCCAGGAAGCCAGCCCTCTGCTCGGCCTCGCCGGCCTCCCTGCTGCAGGCCTCCCTCTCTTCACCGCCTGCGCCTGAGTTCGCGGGT CCTCCGCAGGCCGCCTGGGAACCGGAGCCTGGCGTGCCGGAGCCTGGCCTGGTGCTCTGGGCTCTGCCTTCTGGTTCCTGGAGGCATCAA AGGCTGCATCCGTTCTGCCAACAGCTGTTCGGAGAGACTCGTTCCAGATCATCCCGTCATTTTCAGTTTGTTGGACATTTTACAGCTTCA CCAGGAGAATGTGCAACTTTATTCCAGCATTCGATGCATTTTTATAGAAACACTTTGGAAACACTTTGGATGAACCAAGGCCTTTTCCTT ATTTAAGTAGACTCAGAACACTCCCTTTCTTTTCTTTTCTCTCTCTCTCTCTCTTTTTTTTTTACGAAAGACTTAGAATTGCATTTGTCC TTTTGTGGGTGTCCTGTGAGAGGTGATATGGGGGCTAAGAGGACTGGCTTTCTAATAGAAGAAGTGAGCGCCTGAGAGGACAATTTGGTC ATTGGACACGGATTGCAGGCTTTGAGAAGCGCTCAGAGGCCCAGGGCGGCGGGCTCAGCCATTCGGCTTGGGGCACCAGGCTCCCCAGAG ACAATGCTCAGTATTCATTCATACACAGACGATGGAAGAAGCCACTTCTTCCCTGGGCGGTGTGGGTTTCCCCCAGCTCTTCCCACACGT GTGTTAGGAAATGCCCGTGAACTTGCCCTCTGGGCTTTTTAATGAGAGGCTTGGCGCATGCGGCACCCAGCGGCTGCTTCCCTGCAAGCC AGCGACTTGCCGAGCAGAATGAGCTCTGCTCCTGAGCCCCGGTAGCTGCTTCCTCATCTGCATTTCATCTGGAGCAGGGCAGGTAACCAC AGGAGGAGGCATGCCCGAGGCAGCCAGGACTGGGCGGGAAGGTGCTCCCTGGATATACTCTGTGAACCTTCTGGAAGGCTGCTGGCAGTT TTTCCTTTTTGTCCACCACCCTGCTCTTTTTAATAATTGTACATAATCCGTGTATTTGTTTTACCTGCTCATCTTCTAAACTGGCGAGCC >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000296550_chr4_151023630_+_3253nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCT CATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAA TCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACT GGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGA GTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGAT CTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTC CATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGA GACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACT GGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAAT CTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAA TTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCC CAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGG GTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAG CCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCC CACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGAACCTGGCGCCGCCACCGAGACTGAGCCTCCTGCAGACGGGCGAAGCCGCCT GCTGCAGCCCAGGAAGCCAGCCCTCTGCTCGGCCTCGCCGGCCTCCCTGCTGCAGGCCTCCCTCTCTTCACCGCCTGCGCCTGAGTTCGC GGGTCCTCCGCAGGCCGCCTGGGAACCGGAGCCTGGCGTGCCGGAGCCTGGCCTGGTGCTCTGGGCTCTGCCTTCTGGTTCCTGGAGGCA TCAAAGGCTGCATCCGTTCTGCCAACAGCTGTTCGGAGAGACTCGTTCCAGATCATCCCGTCATTTTCAGTTTGTTGGACATTTTACAGC TTCACCAGGAGAATGTGCAACTTTATTCCAGCATTCGATGCATTTTTATAGAAACACTTTGGAAACACTTTGGATGAACCAAGGCCTTTT CCTTATTTAAGTAGACTCAGAACACTCCCTTTCTTTTCTTTTCTCTCTCTCTCTCTCTTTTTTTTTTACGAAAGACTTAGAATTGCATTT GTCCTTTTGTGGGTGTCCTGTGAGAGGTGATATGGGGGCTAAGAGGACTGGCTTTCTAATAGAAGAAGTGAGCGCCTGAGAGGACAATTT GGTCATTGGACACGGATTGCAGGCTTTGAGAAGCGCTCAGAGGCCCAGGGCGGCGGGCTCAGCCATTCGGCTTGGGGCACCAGGCTCCCC AGAGACAATGCTCAGTATTCATTCATACACAGACGATGGAAGAAGCCACTTCTTCCCTGGGCGGTGTGGGTTTCCCCCAGCTCTTCCCAC ACGTGTGTTAGGAAATGCCCGTGAACTTGCCCTCTGGGCTTTTTAATGAGAGGCTTGGCGCATGCGGCACCCAGCGGCTGCTTCCCTGCA AGCCAGCGACTTGCCGAGCAGAATGAGCTCTGCTCCTGAGCCCCGGTAGCTGCTTCCTCATCTGCATTTCATCTGGAGCAGGGCAGGTAA CCACAGGAGGAGGCATGCCCGAGGCAGCCAGGACTGGGCGGGAAGGTGCTCCCTGGATATACTCTGTGAACCTTCTGGAAGGCTGCTGGC AGTTTTTCCTTTTTGTCCACCACCCTGCTCTTTTTAATAATTGTACATAATCCGTGTATTTGTTTTACCTGCTCATCTTCTAAACTGGCG AGCCCTATAGTTCGTTCTCATTGTTAGATTTTGCCTTTTACAAGTGTCCCCAACCTGCAATAAACTTTTCCCTCTTGAAAAAAAGTAATC >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000506325_chr4_151023630_+_2040nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTTAATGGAACTCCCAGC AGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGTTCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGATTTCTGCTCAT GGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAGCTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCA TCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTCATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGA AAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAATGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTG AAACATCCCAATATCATTATGCTGGTCGAGGAGATGGAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTC TTTGATGCAATTACTTCGTCGACCAAGTACACTGAGAGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCAT GGCCTCAGCATCGTGCACAGAGACATCAAACCAGAGAATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGAC TTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATACACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGC TATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTGATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTC CAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAGCTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTA ATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGGTGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAG GAGAATAACATGCAAGCTGAGGTGACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTC TCCGTCATCATGAACACGGCTCTAGATAAGGAGGGGCAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCC ATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCTGTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCAC >In-frame_MACROD2_ENST00000310348_chr20_13983050_+_DCLK2_ENST00000302176_chr4_151023630_+_3285nt ATGTACCCCAGCAACAAGAAGAAAAAGGTGTGGAGAGAGGAGAAAGAACGTTTATTGAAGATGACCTTAGAAGAGAGACGCAAAGAATAC CTAAGAGACTATATTCCCCTGAACAGCATTCTATCATGGAAGGAGGAGATGAAGGGCAAGGGCCAAAATGATGGTGAGAGTTACGTGTGT GCATCCAATGAACCATTTCGTAAAGTCGATTACACCAAAAATATTAATCCAAACTGGTCTGTGAACATCAAGGGTGGGACATCCCGAGCG CTGGCTGCTGCCTCCTCTGTGAAAAGTGAAGTAAAAGAAAGTAAAGATTTCATCAAACCCAAGTTAGTGACTGTGATTCGAAGTGGAGTG AAGCCTAGAAAAGCCGTGCGGATCCTTCTGAATAAAAAGACTGCTCATTCCTTTGAACAAGTCTTAACAGATATCACCGAAGCCATTAAA CTAGACTCAGGAGTCGTCAAGAGGCTCTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGTGATGACGATGTTTTT ATTGCATGTGGACCAGAAAAATTTCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGTGAATGTCGTGTCCTGAAGTCATCTTATTCT CGATCCTCAGCTGTTAAGTATTCTGGATCCAAAAGCCCTGGGCCCTCTCGACGCAGCAAATCACCAGCTTCAGTAAAGCGGGGTGGCCAC TACTCCAGTGCCTATTCTACAGCCAAATCCCCAGTTAATGGAACTCCCAGCAGCCAACTTTCTACTCCTAAATCTACGAAATCCTCCAGT TCCTCTCCAACTAGTCCAGGAAGTTTCAGAGGATTAAAGCAGATTTCTGCTCATGGCAGATCTTCTTCCAATGTAAACGGTGGACCTGAG CTTGACCGTTGCATAAGTCCTGAAGGTGTGAATGGAAACAGATGCTCTGAATCATCAACTCTTCTTGAGAAATACAAAATTGGAAAGGTC ATTGGTGATGGCAATTTTGCAGTAGTCAAAGAGTGTATAGACAGGTCCACTGGAAAGGAGTTTGCCCTAAAGATTATAGACAAAGCCAAA TGTTGTGGAAAGGAACACCTGATTGAGAATGAAGTGTCAATACTGCGCCGAGTGAAACATCCCAATATCATTATGCTGGTCGAGGAGATG GAAACAGCAACTGAGCTCTTTCTGGTGATGGAATTGGTCAAAGGTGGAGATCTCTTTGATGCAATTACTTCGTCGACCAAGTACACTGAG AGAGATGGCAGTGCCATGGTGTACAACTTAGCCAATGCCCTCAGGTATCTCCATGGCCTCAGCATCGTGCACAGAGACATCAAACCAGAG AATCTCTTGGTGTGTGAATATCCTGATGGAACCAAGTCTTTGAAACTGGGAGACTTTGGGCTTGCGACTGTGGTAGAAGGCCCTTTATAC ACAGTCTGTGGCACACCCACTTATGTGGCTCCAGAAATCATTGCTGAAACTGGCTATGGCCTGAAGGTGGACATTTGGGCAGCTGGTGTG ATCACATACATACTTCTCTGTGGATTCCCACCATTCCGAAGTGAGAACAATCTCCAGGAAGATCTCTTCGACCAGATCTTGGCTGGGAAG CTGGAGTTTCCGGCCCCCTACTGGGATAACATCACGGACTCTGCCAAGGAATTAATCAGTCAAATGCTTCAGGTAAATGTTGAAGCTCGG TGTACCGCGGGACAAATCCTGAGTCACCCCTGGGTGTCAGATGATGCCTCCCAGGAGAATAACATGCAAGCTGAGGTGACAGGTAAACTA AAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACTACCACCGGGGTCTCCGTCATCATGAACACGGCTCTAGATAAGGAGGGG CAGATTTTCTGCAGCAAGCACTGTCAAGACAGCGGCAGGCCTGGGATGGAGCCCATCTCTCCAGTTCCTCCCTCAGTGGAGGAGATCCCT GTGCCTGGGGAAGCAGTCCCGGCCCCCACCCCTCCGGAATCTCCCACCCCCCACCCTCCTCCCGCTGCCCCGGGTGGTGAGCGGGCAGGA ACCTGGCGCCGCCACCGAGACTGAGCCTCCTGCAGACGGGCGAAGCCGCCTGCTGCAGCCCAGGAAGCCAGCCCTCTGCTCGGCCTCGCC GGCCTCCCTGCTGCAGGCCTCCCTCTCTTCACCGCCTGCGCCTGAGTTCGCGGGTCCTCCGCAGGCCGCCTGGGAACCGGAGCCTGGCGT GCCGGAGCCTGGCCTGGTGCTCTGGGCTCTGCCTTCTGGTTCCTGGAGGCATCAAAGGCTGCATCCGTTCTGCCAACAGCTGTTCGGAGA GACTCGTTCCAGATCATCCCGTCATTTTCAGTTTGTTGGACATTTTACAGCTTCACCAGGAGAATGTGCAACTTTATTCCAGCATTCGAT GCATTTTTATAGAAACACTTTGGAAACACTTTGGATGAACCAAGGCCTTTTCCTTATTTAAGTAGACTCAGAACACTCCCTTTCTTTTCT TTTCTCTCTCTCTCTCTCTTTTTTTTTTACGAAAGACTTAGAATTGCATTTGTCCTTTTGTGGGTGTCCTGTGAGAGGTGATATGGGGGC TAAGAGGACTGGCTTTCTAATAGAAGAAGTGAGCGCCTGAGAGGACAATTTGGTCATTGGACACGGATTGCAGGCTTTGAGAAGCGCTCA GAGGCCCAGGGCGGCGGGCTCAGCCATTCGGCTTGGGGCACCAGGCTCCCCAGAGACAATGCTCAGTATTCATTCATACACAGACGATGG AAGAAGCCACTTCTTCCCTGGGCGGTGTGGGTTTCCCCCAGCTCTTCCCACACGTGTGTTAGGAAATGCCCGTGAACTTGCCCTCTGGGC TTTTTAATGAGAGGCTTGGCGCATGCGGCACCCAGCGGCTGCTTCCCTGCAAGCCAGCGACTTGCCGAGCAGAATGAGCTCTGCTCCTGA GCCCCGGTAGCTGCTTCCTCATCTGCATTTCATCTGGAGCAGGGCAGGTAACCACAGGAGGAGGCATGCCCGAGGCAGCCAGGACTGGGC GGGAAGGTGCTCCCTGGATATACTCTGTGAACCTTCTGGAAGGCTGCTGGCAGTTTTTCCTTTTTGTCCACCACCCTGCTCTTTTTAATA ATTGTACATAATCCGTGTATTTGTTTTACCTGCTCATCTTCTAAACTGGCGAGCCCTATAGTTCGTTCTCATTGTTAGATTTTGCCTTTT |
Top |
FusionGenePPI for MACROD2_DCLK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MACROD2 | TERF1, TERF2 | DCLK2 | HSP90AA1, TSC22D3, ENO1, KRAS, DCTN1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for MACROD2_DCLK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for MACROD2_DCLK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MACROD2 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Hgene | MACROD2 | C0023903 | Liver neoplasms | 1 | CTD_human |
| Hgene | MACROD2 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|