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Fusion gene ID: 2027 |
FusionGeneSummary for AP1G1_MTSS1L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AP1G1_MTSS1L | Fusion gene ID: 2027 | Hgene | Tgene | Gene symbol | AP1G1 | MTSS1L | Gene ID | 164 | 92154 |
| Gene name | adaptor related protein complex 1 subunit gamma 1 | MTSS1L, I-BAR domain containing | |
| Synonyms | ADTG|CLAPG1 | ABBA|ABBA-1|ABBA1 | |
| Cytomap | 16q22.2 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AP-1 complex subunit gamma-1adapter-related protein complex 1 subunit gamma-1adaptor protein complex AP-1 subunit gamma-1adaptor related protein complex 1 gamma 1 subunitclathrin assembly protein complex 1 gamma large chainclathrin assembly protein c | MTSS1-like proteinactin-bundling with BAIAP2 homology protein 1metastasis suppressor 1-like | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | O43747 | Q765P7 | |
| Ensembl transtripts involved in fusion gene | ENST00000299980, ENST00000423132, ENST00000433195, ENST00000569748, ENST00000393512, ENST00000570297, ENST00000564155, | ENST00000338779, | |
| Fusion gene scores | * DoF score | 7 X 7 X 5=245 | 5 X 5 X 3=75 |
| # samples | 7 | 5 | |
| ** MAII score | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AP1G1 [Title/Abstract] AND MTSS1L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | MTSS1L | GO:0036120 | cellular response to platelet-derived growth factor stimulus | 20875796 |
| Tgene | MTSS1L | GO:0090630 | activation of GTPase activity | 20875796 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-AB2Q-01A | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000299980 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| Frame-shift | ENST00000423132 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| In-frame | ENST00000433195 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| Frame-shift | ENST00000569748 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| Frame-shift | ENST00000393512 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| intron-3CDS | ENST00000570297 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
| Frame-shift | ENST00000564155 | ENST00000338779 | AP1G1 | chr16 | 71779047 | - | MTSS1L | chr16 | 70698999 | - |
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FusionProtFeatures for AP1G1_MTSS1L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AP1G1 | MTSS1L |
| Subunit of clathrin-associated adaptor protein complex 1that plays a role in protein sorting in the late-Golgi/trans-Golginetwork (TGN) and/or endosomes. The AP complexes mediate both therecruitment of clathrin to membranes and the recognition ofsorting signals within the cytosolic tails of transmembrane cargomolecules. | Involved in plasma membrane dynamics. Potentiated PDGF-mediated formation of membrane ruffles and lamellipodia infibroblasts, acting via RAC1 activation (PubMed:14752106). Mayfunction in actin bundling (PubMed:14752106).{ECO:0000269|PubMed:14752106}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for AP1G1_MTSS1L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AP1G1_ENST00000433195_chr16_71779047_-_MTSS1L_ENST00000338779_chr16_70698999_-_1061aa MEKNINLRNCQTLNTYVMLTHLRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQ LECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKA ALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQV RILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQ TDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLT TAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNM STSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEP APLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGLVQGRLPXAALRRHSAAEEGPSGAPARHRA RPCQWGHPGPQRGRGTATPDVPCHHRSQARXGGVPRRQXPGHGADAGPEPGAPEEQPGLAAVLQRLQHADHHALLLXGHHPLPRLRLRLL LREWGCGQRGPARVXQVIHHPAQQQHRPELPPPDPDQAPSLHCWAAHRGAAHGHWPALGRTPRRGHHPPHTLHQAHRAPRPVQRWPHPHP AAHRPCEDAHGAXLPRLHGAHTGGQXGVRLLYRRDRLTPGTGPRQGLPKEAQPAQHSLGQPIPRGSRVPRGRGRGRAAAAGGQPAQPGGE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AP1G1_ENST00000433195_chr16_71779047_-_MTSS1L_ENST00000338779_chr16_70698999_-_3184nt ATGGAGAAAAATATTAATCTGAGGAACTGTCAAACACTGAACACCTATGTAATGCTCACTCATTTAAGGATGCCAGCCCCCATCAGATTG CGGGAGCTGATCCGGACCATCCGGACAGCCCGAACCCAAGCTGAAGAACGAGAAATGATCCAGAAAGAATGTGCTGCAATCCGGTCATCT TTTAGAGAAGAAGACAATACATACCGATGTCGGAATGTGGCAAAATTACTGTATATGCACATGCTGGGCTACCCTGCTCACTTTGGACAG TTGGAGTGCCTCAAGCTTATTGCCTCTCAAAAATTTACAGACAAACGCATTGGCTATTTAGGGGCAATGCTGCTGTTAGATGAAAGACAA GATGTCCATCTTCTCATGACCAACTGTATCAAGAATGATCTTAATCATAGCACGCAATTCGTACAGGGGTTAGCACTTTGTACCCTCGGC TGCATGGGCTCCTCAGAGATGTGCAGAGATCTTGCAGGAGAGGTAGAGAAGCTCCTGAAAACCTCCAACTCTTACTTAAGAAAAAAGGCA GCACTGTGTGCTGTTCATGTCATCAGGAAAGTTCCTGAACTTATGGAGATGTTTTTACCAGCAACAAAAAATTTATTGAATGAGAAGAAC CATGGTGTCCTCCACACATCTGTAGTCCTCCTCACAGAAATGTGTGAGCGAAGCCCAGACATGCTTGCGCATTTCAGAAAGCTTGTGCCC CAATTAGTTCGTATTTTAAAGAACCTCATCATGTCCGGATATTCACCAGAACATGATGTTTCTGGTATCAGTGACCCCTTTTTGCAGGTA CGAATTTTGCGGTTATTAAGAATTTTAGGACGAAATGATGATGATTCAAGTGAAGCTATGAATGATATATTAGCACAGGTTGCCACTAAT ACTGAGACTAGTAAAAATGTAGGAAATGCTATTCTTTATGAAACGGTTTTGACTATCATGGATATTAAGTCAGAGAGTGGATTGCGAGTC CTAGCCATAAATATCCTGGGTCGTTTCTTATTGAACAATGACAAGAATATTAGATATGTGGCTCTGACATCTTTGTTGAAGACTGTACAG ACAGATCATAATGCAGTACAGAGGCACAGAAGCACAATTGTGGACTGTCTTAAAGATTTGGATGTCTCAATAAAACGGCGTGCAATGGAA TTGAGTTTTGCCCTGGTAAATGGGAATAATATCCGAGGCATGATGAAAGAATTACTTTATTTTCTGGATTCGTGTGAGCCAGAATTTAAA GCAGACTGTGCATCTGGAATCTTTCTTGCTGCAGAAAAGTATGCACCTTCCAAACGATGGCATATAGACACAATTATGCGTGTTTTGACA ACGGCAGGAAGTTATGTTCGTGATGATGCAGTCCCCAATTTAATCCAGTTAATAACTAATAGTGTGGAGATGCATGCCTATACTGTCCAG CGCCTGTACAAAGCAATTCTTGGTGATTATTCTCAACAACCTTTGGTACAAGTGGCTGCATGGTGTATAGGTGAATATGGTGATCTTCTT GTATCTGGCCAGTGTGAAGAGGAAGAGCCTATTCAGGTAACAGAGGATGAAGTGTTGGATATTTTAGAAAGTGTCCTAATCTCTAATATG TCCACCTCTGTGACACGAGGTTATGCCCTCACTGCCATTATGAAGCTTTCCACTCGATTCACTTGTACTGTAAACCGAATTAAGAAAGTG GTTTCCATCTACGGAAGCAGCATTGATGTGGAACTCCAGCAGAGGGCAGTAGAATATAATGCACTTTTCAAGAAATATGACCACATGAGG TCTGCCCTACTTGAGAGAATGCCTGTCATGGAAAAAGTGACCACAAATGGCCCTACTGAGATTGTGCAGACAAATGGAGAGACAGAACCA GCTCCACTAGAGACCAAACCGCCACCCTCTGGGCCACAGCCCACCAGCCAGGCCAATGATTTATTGGATTTGTTGGGAGGAAATGACATA ACACCTGTTATTCCAACTGCGCCTACAAGCAAACCATCTTCTGCTGGTGGAGAACTTCTTGATTTGCTGGGAGACATCAACCTTACAGGA CTGGTCCAAGGTCGGCTCCCATGAGCAGCCCTCAGGCGCCACTCTGCAGCGGAGGAAGGACCGAGTGGAGCTCCTGCGAGACACAGAGCC AGGCCCTGCCAGTGGGGGCACCCTGGGCCCCAGCGGGGAAGAGGCACCGCGACCCCGGATGTCCCCTGCCACCATCGCAGCCAAGCACGG TGAGGAGGTGTCCCCCGCCGCCAGTGACCTGGCCATGGTGCTGACGCGGGGCCTGAGCCTGGAGCACCAGAAGAGCAGCCGGGACTCGCT GCAGTACTCCAGCGGCTACAGCACGCAGACCACCACGCCCTCCTGCTCTGAGGACACCATCCCCTCCCAAGGCTCCGACTACGACTGCTA CTCCGTGAATGGGGATGCGGACAGCGAGGGCCCGCCCGAGTTTGACAAGTCATCCACCATCCCGCGCAACAGCAACATCGCCCAGAACTA CCGCCGCCTGATCCAGACCAAGCGCCCAGCCTCCACTGCTGGGCTGCCCACCGCGGGGCTGCCCACGGCCACTGGCCTGCCCTCGGGCGC ACCCCCCGGCGTGGCCACCATCCGCCGCACACCCTCCACCAAGCCCACCGTGCGCCGCGCCCTGTCCAGCGCTGGCCCCATCCCCATCCG GCCGCCCATCGTCCCTGTGAAGACGCCCACGGTGCCTGACTCCCCCGGCTACATGGGGCCCACACGGGCGGGCAGTGAGGAGTGCGTCTT CTATACCGACGAGACCGCCTCACCCCTGGCACCGGACCTCGCCAAGGCCTCCCCAAAGAGGCTCAGCCTGCCCAACACAGCCTGGGGCAG CCCATCCCCAGAGGCAGCCGGGTACCCCGGGGCAGGGGCCGAGGACGAGCAGCAGCAGCTGGCGGCCAACCGGCACAGCCTGGTGGAGAA GCTGGGGGAGCTGGTGGCGGGTGCCCACGCACTGGGTGAGGGCCAGTTCCCCTTCCCCACTGCTCTGTCGGCCACCCCCACGGAGGAGAC GCCCACCCCACCCCCAGCCGCCACCAGCGACCCCCCGGCCGAAGACATGCTGGTGGCCATCCGGCGTGGGGTCCGGCTCCGCAGGACCGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AP1G1_ENST00000433195_chr16_71779047_-_MTSS1L_ENST00000338779_chr16_70698999_-_6457nt AGCAGTCGCCTCCTCCTTGGCAAATAGTCCTCGGCAGGGTCCGAGTTCTTGGATAATTCGAGAGAAAAGGCACGATAAGTTGCAGTACGA GGACACGGAAACGACCAGGAGAGGAGGACAGGGAGCGAAGTTTCCTCAATAGTGTGTGAAGTTAGTTAAAAACTCCCTCCTTCCTCAGGA TCCCTCCGCCTGCGGTAGCGGTGGTGAGGCCGAGGGAGCCGCCATTTTGGATGTTCGGTTCCTGCTGCCACTGCTGCCGCCGCCCCCGGA GCTGCTGGTTTCATTCGAGGTTTCGGGCCGTTTCAGGGGTCCAGTCCCAGGCTGTGGGTGTTGAGAAGAGAAGACAGAGAAGCTGGGCCA GGAGAGGCCGGGAGCCCCAGGGGCTGCTCCGACTTCTGGAGGGCCGACCCCGAGGCCTCGGACCGGGAGGTTCCGCGCGCCGCGGCGTTC CGTGTTGTGGCGTTGCCCCGCCGCTCCTGGCCCTGCGGACGTCAGCGTCTAATAATTCTCCCGGTCTTCCTGATTGCCTGAAAGAGTCGG GACGGTTCGGTTGATTGTGTTTCCCGGTTAGGACTCGGTGTAGGAGATCCATCGAACCACTCGCTCAGGGTAATGTTTATGAAGCAGATT ATGTTTATGAAGCAGATTAAATGGCTTTTGGGAGGCAAGAGCTGTCAAATGTTTTCTCATATGTGGATTCCCTCCCTGTGCTGAATACTT AGCTTTTTGGTGCTTACTGACACTTGTGTGGTATTTTTTTTTCTCCCCTATTATATATCCCTGAGCACGGAAATCTGTCCATGGAGAAAA ATATTAATCTGAGGAACTGTCAAACACTGAACACCTATGTAATGCTCACTCATTTAAGGATGCCAGCCCCCATCAGATTGCGGGAGCTGA TCCGGACCATCCGGACAGCCCGAACCCAAGCTGAAGAACGAGAAATGATCCAGAAAGAATGTGCTGCAATCCGGTCATCTTTTAGAGAAG AAGACAATACATACCGATGTCGGAATGTGGCAAAATTACTGTATATGCACATGCTGGGCTACCCTGCTCACTTTGGACAGTTGGAGTGCC TCAAGCTTATTGCCTCTCAAAAATTTACAGACAAACGCATTGGCTATTTAGGGGCAATGCTGCTGTTAGATGAAAGACAAGATGTCCATC TTCTCATGACCAACTGTATCAAGAATGATCTTAATCATAGCACGCAATTCGTACAGGGGTTAGCACTTTGTACCCTCGGCTGCATGGGCT CCTCAGAGATGTGCAGAGATCTTGCAGGAGAGGTAGAGAAGCTCCTGAAAACCTCCAACTCTTACTTAAGAAAAAAGGCAGCACTGTGTG CTGTTCATGTCATCAGGAAAGTTCCTGAACTTATGGAGATGTTTTTACCAGCAACAAAAAATTTATTGAATGAGAAGAACCATGGTGTCC TCCACACATCTGTAGTCCTCCTCACAGAAATGTGTGAGCGAAGCCCAGACATGCTTGCGCATTTCAGAAAGCTTGTGCCCCAATTAGTTC GTATTTTAAAGAACCTCATCATGTCCGGATATTCACCAGAACATGATGTTTCTGGTATCAGTGACCCCTTTTTGCAGGTACGAATTTTGC GGTTATTAAGAATTTTAGGACGAAATGATGATGATTCAAGTGAAGCTATGAATGATATATTAGCACAGGTTGCCACTAATACTGAGACTA GTAAAAATGTAGGAAATGCTATTCTTTATGAAACGGTTTTGACTATCATGGATATTAAGTCAGAGAGTGGATTGCGAGTCCTAGCCATAA ATATCCTGGGTCGTTTCTTATTGAACAATGACAAGAATATTAGATATGTGGCTCTGACATCTTTGTTGAAGACTGTACAGACAGATCATA ATGCAGTACAGAGGCACAGAAGCACAATTGTGGACTGTCTTAAAGATTTGGATGTCTCAATAAAACGGCGTGCAATGGAATTGAGTTTTG CCCTGGTAAATGGGAATAATATCCGAGGCATGATGAAAGAATTACTTTATTTTCTGGATTCGTGTGAGCCAGAATTTAAAGCAGACTGTG CATCTGGAATCTTTCTTGCTGCAGAAAAGTATGCACCTTCCAAACGATGGCATATAGACACAATTATGCGTGTTTTGACAACGGCAGGAA GTTATGTTCGTGATGATGCAGTCCCCAATTTAATCCAGTTAATAACTAATAGTGTGGAGATGCATGCCTATACTGTCCAGCGCCTGTACA AAGCAATTCTTGGTGATTATTCTCAACAACCTTTGGTACAAGTGGCTGCATGGTGTATAGGTGAATATGGTGATCTTCTTGTATCTGGCC AGTGTGAAGAGGAAGAGCCTATTCAGGTAACAGAGGATGAAGTGTTGGATATTTTAGAAAGTGTCCTAATCTCTAATATGTCCACCTCTG TGACACGAGGTTATGCCCTCACTGCCATTATGAAGCTTTCCACTCGATTCACTTGTACTGTAAACCGAATTAAGAAAGTGGTTTCCATCT ACGGAAGCAGCATTGATGTGGAACTCCAGCAGAGGGCAGTAGAATATAATGCACTTTTCAAGAAATATGACCACATGAGGTCTGCCCTAC TTGAGAGAATGCCTGTCATGGAAAAAGTGACCACAAATGGCCCTACTGAGATTGTGCAGACAAATGGAGAGACAGAACCAGCTCCACTAG AGACCAAACCGCCACCCTCTGGGCCACAGCCCACCAGCCAGGCCAATGATTTATTGGATTTGTTGGGAGGAAATGACATAACACCTGTTA TTCCAACTGCGCCTACAAGCAAACCATCTTCTGCTGGTGGAGAACTTCTTGATTTGCTGGGAGACATCAACCTTACAGGACTGGTCCAAG GTCGGCTCCCATGAGCAGCCCTCAGGCGCCACTCTGCAGCGGAGGAAGGACCGAGTGGAGCTCCTGCGAGACACAGAGCCAGGCCCTGCC AGTGGGGGCACCCTGGGCCCCAGCGGGGAAGAGGCACCGCGACCCCGGATGTCCCCTGCCACCATCGCAGCCAAGCACGGTGAGGAGGTG TCCCCCGCCGCCAGTGACCTGGCCATGGTGCTGACGCGGGGCCTGAGCCTGGAGCACCAGAAGAGCAGCCGGGACTCGCTGCAGTACTCC AGCGGCTACAGCACGCAGACCACCACGCCCTCCTGCTCTGAGGACACCATCCCCTCCCAAGGCTCCGACTACGACTGCTACTCCGTGAAT GGGGATGCGGACAGCGAGGGCCCGCCCGAGTTTGACAAGTCATCCACCATCCCGCGCAACAGCAACATCGCCCAGAACTACCGCCGCCTG ATCCAGACCAAGCGCCCAGCCTCCACTGCTGGGCTGCCCACCGCGGGGCTGCCCACGGCCACTGGCCTGCCCTCGGGCGCACCCCCCGGC GTGGCCACCATCCGCCGCACACCCTCCACCAAGCCCACCGTGCGCCGCGCCCTGTCCAGCGCTGGCCCCATCCCCATCCGGCCGCCCATC GTCCCTGTGAAGACGCCCACGGTGCCTGACTCCCCCGGCTACATGGGGCCCACACGGGCGGGCAGTGAGGAGTGCGTCTTCTATACCGAC GAGACCGCCTCACCCCTGGCACCGGACCTCGCCAAGGCCTCCCCAAAGAGGCTCAGCCTGCCCAACACAGCCTGGGGCAGCCCATCCCCA GAGGCAGCCGGGTACCCCGGGGCAGGGGCCGAGGACGAGCAGCAGCAGCTGGCGGCCAACCGGCACAGCCTGGTGGAGAAGCTGGGGGAG CTGGTGGCGGGTGCCCACGCACTGGGTGAGGGCCAGTTCCCCTTCCCCACTGCTCTGTCGGCCACCCCCACGGAGGAGACGCCCACCCCA CCCCCAGCCGCCACCAGCGACCCCCCGGCCGAAGACATGCTGGTGGCCATCCGGCGTGGGGTCCGGCTCCGCAGGACCGTCACCAACGAC AGGTCGGCGCCCCGCATCTTATGATGGCGCCACCCTCCCCATCCTCTCAGGCCCCAGTGCGAGCAGGTGGCCTGGTCTGTGAGCCGCAGG CACTCAGAGCAAAGGCCCAGCCAGGAGAGAGGACAGAGCCAGGGCAGAGGCCATGCCACTTTATGGAAAGACACCTCACTTGGATTCCAG CATTTAAACAGGAAGTGACTTCTTAGCAAGCCTGGCCAGGACGGAGCCTGCAGGCCTGGGCCTGGTTCGGGGTCTGTTTTATGCTCTTCG GTCCCTCCTCTTCCTCCTCTGGGGCCCTGCCTCTTCCCTACCCATAAGCACCAGAGCCAGGGCCGCTGCCCATGACAGAGGGGCCAGGCT GGCCTCCCTTTCACCATCCCGGCCTCTCCCAGGGCTGGTCCTGCCTCAGCTCCTCCTGGAATGCTGGCCCCCCTCTCCCCTGCCTGAGCC CCCTCCTCCCCTCTTGCCTTCTCTCTGCCTCTCCCAGGCCCCTCTCCCTCCAGGAGGCGGGGCGGCTGTGGAGGGGCCAGGTGCACGCTG GGCTGGATGTCTGCTGGGGGCTGGGGGCCAGGGCGGCAGGTTGGAGTTGGGCGGCCAGGCCCCCCGTGTGGGAAGGGAGTTCCAGGGCCC ACGCCAAGTCTCAGGGAGGAAACCAGGGGCTGCTTGGGGGGGGGGGTCTTGGGGGCCCTGTGGTGGCTCCCACCCCTCGCCTCCCCCACC CCGTGAGGCTGGCTGGAGGGGGCCAGAGCAGCTCTTTGGAAACTAGGGCAGCAGGGTTAGGAGGCCGGAGGCCCTGGGGTCACCGGCCAG CCACACAGGCACCGTTTTCAGATGTCCACTTCTCATTGGGTACATCAATCTTTTAACTTTGGGGGTCACAGTTTTAGCCACCTTTCGGGG GGTGACTGGAGCAGTAGGAGGTGTGGGGTCATTTTATGAATATAATAAAATGGAGCTGACTGTGGACGAGGACTAAGTGTGGGGGAGAGG GGACGATACAGGGTGTGTGTCTGGGAGTGCCTGGGGGACAGGGACCCCCCGGTGGTCCTATGGCAGGATGAGAAGGGAGGGACTTGGCTC CCCCAGAGCCCGGTGGAAGCTACTGTTCTCTCCAGTGTCTCGAGCGTAGCCAAAATAAGGTTGGGAGGCTCCCGGCCTGTCTGCTGTGGT CTGAGCTGGCTGCAAGCCCAGGTGGGGGAGCGAGTCTGGGAAGATTGGCTTTGACTCTCTGTTGCCGGAGGAGATGCCATCCCAGCACGG CCCCCACTGTAGTCCAGGCTCGTGGTGGCAGCGGGGGCAAGGGGAGGGGCAAGGCTGCCCCCACCCCACGCACCAAGTCACGCCAAGTCT CAGCAGGTAAAAGCACGTGAGCCTAGGGCGAGCGGAGGGAGTCCTGGTGGCCCCGCAGGTCAGGAGGGAAAGCAGGGCTCAGAGGGCATC GTGGCCCCAGGGCAGGGTCCTACCTGGGGGTCAGGAGCACCTTGGTCTTGATGATTGATTGATTGATTGATAGAATGGAGCTGGGTCTGA GCCTCCCAGGCTTGAGCTCCTGGGAGTTCTTGTGCGGTGAGCTGGGCAGCTCCTGGGTAGGTCCGGGCACCAAGCAGGCCCTGATGTGGA CAGAGTCCCATCAGAGGGAGCTGATGAAGAATGGTCCCTGTAAGTAAGTCACTAGGTTCAACAACTGCCTGGCCGAGCACTCAGCCCGTG GAGCTCAGGCCAACACCAGAGCCCCGGTTTTAGGGGCCAGGAGAGCAGGTGACCAATTATTTGGGGAGTCTTGGGTAGAATTTCCGCCAC ACATTCTCCCCAGGGCTGCAGGGGTCTTCCGAGGCAGGGCGGTGGAGCAGGATTCAGGATGTGGTGGGAATAGAGTGAGGGGCAGTGGGT GGGCAGACCTGGGCGTCAGAGGTCCTGATGGGAAAGGAGGCAGGGGCTACCCAGAGAGGGGGGCTCGTGTGGCACAGCCCCCACCGACTC CGCCGTCCCCCTCCCCTGTGAGCCCCGGGGGCTGTACATACTCTACTCCATCCCCTTGTCCATCCCTGAGACCACCCCCGCCGCCCTTGC GTCGACTTAGCAACCACCTCATAGGCCCACCCACCTCGGGATCCGAGCCAACCATCCCACATCACAAACTTTGGTTTGGGGGACTTTACG TTCGTTTAATTTCTCATTTTGTACGGAGAAATATTCTTTTCAAAAGCGTCTTTTGACTGAAGTAACTTTCCTGGTGCTGTTGTTAACTCG TTCCTTTTTTTAATTTATTCCCCCACCCCAGGCAGCCCTCCTGGTTCCTACTCACCCTCCCCCCCTCCCCCACCCTCCGTCCCATCTGAA CCATTTGTTTCTTTTCTTTCCGTCAGATTTTGGAAAAATTCTCCTCTCCTCCCCGCCCCCTCCACACCATCCTCCCCGATTTAAATATAG |
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FusionGenePPI for AP1G1_MTSS1L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AP1G1 | SYP, AP1B1, AP1S1, AP1S2, NECAP1, NECAP2, ARF1, SYNRG, RABEP1, CLINT1, AP1M2, AP1M1, KIF13A, AP2M1, AP2S1, JUN, CLTC, ZNF512B, MAP1A, EGFR, NPM3, OSBPL11, PRRC1, TRIP10, ASB10, GPRASP2, PASK, UBL7, CORO7, AAGAB, UNK, DNAJC13, FLNB, GDA, PAFAH1B1, PRKAB1, UBA1, AP2B1, DCPS, NTRK1, XPO1, GTSE1, GGA1, AMPH, SENP3, EPS15, ZNF746, POTEB3, PPP6R2, ARF6, BAALC | MTSS1L | FUS, FBXW11 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AP1G1_MTSS1L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AP1G1_MTSS1L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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