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Fusion gene ID: 20124 |
FusionGeneSummary for LRP1_BCAN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LRP1_BCAN | Fusion gene ID: 20124 | Hgene | Tgene | Gene symbol | LRP1 | BCAN | Gene ID | 10438 | 63827 |
| Gene name | C1D nuclear receptor corepressor | brevican | |
| Synonyms | LRP1|Rrp47|SUN-CoR|SUNCOR|hC1D | BEHAB|CSPG7 | |
| Cytomap | 2p14 | 1q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nuclear nucleic acid-binding protein C1DC1D DNA-binding proteinC1D nuclear receptor co-repressornuclear DNA-binding proteinsmall unique nuclear receptor co-repressorsmall unique nuclear receptor corepressor | brevican core proteinbrain-enriched hyaluronan-binding proteinchondroitin sulfate proteoglycan 7chondroitin sulfate proteoglycan BEHAB | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q07954 | Q96GW7 | |
| Ensembl transtripts involved in fusion gene | ENST00000553277, ENST00000243077, ENST00000338962, ENST00000554174, ENST00000553446, | ENST00000329117, ENST00000361588, | |
| Fusion gene scores | * DoF score | 16 X 14 X 7=1568 | 3 X 1 X 2=6 |
| # samples | 17 | 3 | |
| ** MAII score | log2(17/1568*10)=-3.20531890797751 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/6*10)=2.32192809488736 | |
| Context | PubMed: LRP1 [Title/Abstract] AND BCAN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-CS-6186-01A | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000553277 | ENST00000329117 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-intron | ENST00000553277 | ENST00000361588 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| In-frame | ENST00000243077 | ENST00000329117 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| 5CDS-intron | ENST00000243077 | ENST00000361588 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-3CDS | ENST00000338962 | ENST00000329117 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-intron | ENST00000338962 | ENST00000361588 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-3CDS | ENST00000554174 | ENST00000329117 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-intron | ENST00000554174 | ENST00000361588 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-3CDS | ENST00000553446 | ENST00000329117 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
| intron-intron | ENST00000553446 | ENST00000361588 | LRP1 | chr12 | 57596320 | + | BCAN | chr1 | 156627467 | + |
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FusionProtFeatures for LRP1_BCAN |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LRP1 | BCAN |
| Endocytic receptor involved in endocytosis and inphagocytosis of apoptotic cells. Required for early embryonicdevelopment. Involved in cellular lipid homeostasis. Involved inthe plasma clearance of chylomicron remnants and activated LRPAP1(alpha 2-macroglobulin), as well as the local metabolism ofcomplexes between plasminogen activators and their endogenousinhibitors. May modulate cellular events, such as APP metabolism,kinase-dependent intracellular signaling, neuronal calciumsignaling as well as neurotransmission (PubMed:11907044,PubMed:12888553, PubMed:12713657). Acts as an alpha-2-macroglobulin receptor (PubMed:26142438).{ECO:0000269|PubMed:11907044, ECO:0000269|PubMed:12713657,ECO:0000269|PubMed:12888553, ECO:0000269|PubMed:26142438}. (Microbial infection) Functions as a receptor forPseudomonas aeruginosa exotoxin A. {ECO:0000269|PubMed:1618748}. | May play a role in the terminally differentiating andthe adult nervous system during postnatal development. Couldstabilize interactions between hyaluronan (HA) and brainproteoglycans. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for LRP1_BCAN |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LRP1_ENST00000243077_chr12_57596320_+_BCAN_ENST00000329117_chr1_156627467_+_3746aa MLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSR LCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYL LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPGLKGFVDE HTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTK LVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEY QVVTRVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRG MDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVA RLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFY DRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVN NGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRF KCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCI NINWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRW RCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGND DCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGES CRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLA VDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWPNGLT VDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHP SRQPMAPNPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVPDIDNVTVL DYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLEQPHGLVVH PLRGKLYWTDGDNISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATALAIMGDKLW WADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVG SFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIY WTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCD ARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCA VANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPG TPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLD ECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGE HIFWTDWVRRAVQRANKHVGSNMKLLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAV NSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEF RCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNY FACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPE RWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWECDG ENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPG FRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAV ALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRAL VVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLF EDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTC VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKC TNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPA RWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCNRYREYQWIGLNDRTIEGDFLWSDGVPLLY ENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPLI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LRP1_ENST00000243077_chr12_57596320_+_BCAN_ENST00000329117_chr1_156627467_+_11238nt ATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAAGACTTGCAGCCCCAAG CAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGACGGATCTGACGAGGCC CCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTGTGTTCCCATGTCCCGC CTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTGCTCTCGCCTGGGCTGC CAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGGCAAGACCTGCAAAGAT TTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTGTGTTGAAGGATACCTC CTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAACTCCCAGAACATCTTG GCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTTCAGCTATGCCAACGAG ACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAAGGGCTTCGTGGATGAG CACACCATCAACATCTCCCTCAGTCTGCACCACGTGGAACAGATGGCCATCGACTGGCTGACAGGCAACTTCTACTTTGTGGATGACATC GATGATAGGATCTTTGTCTGCAACAGAAATGGGGACACATGTGTCACATTGCTAGACCTGGAACTCTACAACCCCAAGGGCATTGCCCTG GACCCTGCCATGGGGAAGGTGTTTTTCACTGACTATGGGCAGATCCCAAAGGTGGAACGCTGTGACATGGATGGGCAGAACCGCACCAAG CTCGTCGACAGCAAGATTGTGTTTCCTCATGGCATCACGCTGGACCTGGTCAGCCGCCTTGTCTACTGGGCAGATGCCTATCTGGACTAT ATTGAAGTGGTGGACTATGAGGGCAAGGGCCGCCAGACCATCATCCAGGGCATCCTGATTGAGCACCTGTACGGCCTGACTGTGTTTGAG AATTATCTCTATGCCACCAACTCGGACAATGCCAATGCCCAGCAGAAGACGAGTGTGATCCGTGTGAACCGCTTTAACAGCACCGAGTAC CAGGTTGTCACCCGGGTGGACAAGGGTGGTGCCCTCCACATCTACCACCAGAGGCGTCAGCCCCGAGTGAGGAGCCATGCCTGTGAAAAC GACCAGTATGGGAAGCCGGGTGGCTGCTCTGACATCTGCCTGCTGGCCAACAGCCACAAGGCGCGGACCTGCCGCTGCCGTTCCGGCTTC AGCCTGGGCAGTGACGGGAAGTCATGCAAGAAGCCGGAGCATGAGCTGTTCCTCGTGTATGGCAAGGGCCGGCCAGGCATCATCCGGGGC ATGGATATGGGGGCCAAGGTCCCGGATGAGCACATGATCCCCATTGAAAACCTCATGAACCCCCGAGCCCTGGACTTCCACGCTGAGACC GGCTTCATCTACTTTGCCGACACCACCAGCTACCTCATTGGCCGCCAGAAGATTGATGGCACTGAGCGGGAGACCATCCTGAAGGACGGC ATCCACAATGTGGAGGGTGTGGCCGTGGACTGGATGGGAGACAATCTGTACTGGACGGACGATGGGCCCAAAAAGACAATCAGCGTGGCC AGGCTGGAGAAAGCTGCTCAGACCCGCAAGACTTTAATCGAGGGCAAAATGACACACCCCAGGGCTATTGTGGTGGATCCACTCAATGGG TGGATGTACTGGACAGACTGGGAGGAGGACCCCAAGGACAGTCGGCGTGGGCGGCTGGAGAGGGCGTGGATGGATGGCTCACACCGAGAC ATCTTTGTCACCTCCAAGACAGTGCTTTGGCCCAATGGGCTAAGCCTGGACATCCCGGCTGGGCGCCTCTACTGGGTGGATGCCTTCTAC GACCGCATCGAGACGATACTGCTCAATGGCACAGACCGGAAGATTGTGTATGAAGGTCCTGAGCTGAACCACGCCTTTGGCCTGTGTCAC CATGGCAACTACCTCTTCTGGACTGAGTATCGGAGTGGCAGTGTCTACCGCTTGGAACGGGGTGTAGGAGGCGCACCCCCCACTGTGACC CTTCTGCGCAGTGAGCGGCCCCCCATCTTTGAGATCCGAATGTATGATGCCCAGCAGCAGCAAGTTGGCACCAACAAATGCCGGGTGAAC AATGGCGGCTGCAGCAGCCTGTGCTTGGCCACCCCTGGGAGCCGCCAGTGCGCCTGTGCTGAGGACCAGGTGTTGGACGCAGACGGCGTC ACTTGCTTGGCGAACCCATCCTACGTGCCTCCACCCCAGTGCCAGCCAGGCGAGTTTGCCTGTGCCAACAGCCGCTGCATCCAGGAGCGC TGGAAGTGTGACGGAGACAACGATTGCCTGGACAACAGTGATGAGGCCCCAGCCCTCTGCCATCAGCACACCTGCCCCTCGGACCGATTC AAGTGCGAGAACAACCGGTGCATCCCCAACCGCTGGCTCTGCGACGGGGACAATGACTGTGGGAACAGTGAAGATGAGTCCAATGCCACT TGTTCAGCCCGCACCTGCCCCCCCAACCAGTTCTCCTGTGCCAGTGGCCGCTGCATCCCCATCTCCTGGACGTGTGATCTGGATGACGAC TGTGGGGACCGCTCTGATGAGTCTGCTTCGTGTGCCTATCCCACCTGCTTCCCCCTGACTCAGTTTACCTGCAACAATGGCAGATGTATC AACATCAACTGGAGATGCGACAATGACAATGACTGTGGGGACAACAGTGACGAAGCCGGCTGCAGCCACTCCTGTTCTAGCACCCAGTTC AAGTGCAACAGCGGGCGTTGCATCCCCGAGCACTGGACCTGCGATGGGGACAATGACTGCGGAGACTACAGTGATGAGACACACGCCAAC TGCACCAACCAGGCCACGAGGCCCCCTGGTGGCTGCCACACTGATGAGTTCCAGTGCCGGCTGGATGGACTATGCATCCCCCTGCGGTGG CGCTGCGATGGGGACACTGACTGCATGGACTCCAGCGATGAGAAGAGCTGTGAGGGAGTGACCCACGTCTGCGATCCCAGTGTCAAGTTT GGCTGCAAGGACTCAGCTCGGTGCATCAGCAAAGCGTGGGTGTGTGATGGCGACAATGACTGTGAGGATAACTCGGACGAGGAGAACTGC GAGTCCCTGGCCTGCAGGCCACCCTCGCACCCTTGTGCCAACAACACCTCAGTCTGCCTGCCCCCTGACAAGCTGTGTGATGGCAACGAC GACTGTGGCGACGGCTCAGATGAGGGCGAGCTCTGCGACCAGTGCTCTCTGAATAACGGTGGCTGCAGCCACAACTGCTCAGTGGCACCT GGCGAAGGCATTGTGTGTTCCTGCCCTCTGGGCATGGAGCTGGGGCCCGACAACCACACCTGCCAGATCCAGAGCTACTGTGCCAAGCAT CTCAAATGCAGCCAAAAGTGCGACCAGAACAAGTTCAGCGTGAAGTGCTCCTGCTACGAGGGCTGGGTCCTGGAACCTGACGGCGAGAGC TGCCGCAGCCTGGACCCCTTCAAGCCGTTCATCATTTTCTCCAACCGCCATGAAATCCGGCGCATCGATCTTCACAAAGGAGACTACAGC GTCCTGGTGCCCGGCCTGCGCAACACCATCGCCCTGGACTTCCACCTCAGCCAGAGCGCCCTCTACTGGACCGACGTGGTGGAGGACAAG ATCTACCGCGGGAAGCTGCTGGACAACGGAGCCCTGACTAGTTTCGAGGTGGTGATTCAGTATGGCCTGGCCACACCCGAGGGCCTGGCT GTAGACTGGATTGCAGGCAACATCTACTGGGTGGAGAGTAACCTGGATCAGATCGAGGTGGCCAAGCTGGATGGGACCCTCCGGACCACC CTGCTGGCCGGTGACATTGAGCACCCAAGGGCAATCGCACTGGATCCCCGGGATGGGATCCTGTTTTGGACAGACTGGGATGCCAGCCTG CCCCGCATTGAGGCAGCCTCCATGAGTGGGGCTGGGCGCCGCACCGTGCACCGGGAGACCGGCTCTGGGGGCTGGCCCAACGGGCTCACC GTGGACTACCTGGAGAAGCGCATCCTTTGGATTGACGCCAGGTCAGATGCCATTTACTCAGCCCGTTACGACGGCTCTGGCCACATGGAG GTGCTTCGGGGACACGAGTTCCTGTCGCACCCGTTTGCAGTGACGCTGTACGGGGGGGAGGTCTACTGGACTGACTGGCGAACAAACACA CTGGCTAAGGCCAACAAGTGGACCGGCCACAATGTCACCGTGGTACAGAGGACCAACACCCAGCCCTTTGACCTGCAGGTGTACCACCCC TCCCGCCAGCCCATGGCTCCCAATCCCTGTGAGGCCAATGGGGGCCAGGGCCCCTGCTCCCACCTGTGTCTCATCAACTACAACCGGACC GTGTCCTGCGCCTGCCCCCACCTCATGAAGCTCCACAAGGACAACACCACCTGCTATGAGTTTAAGAAGTTCCTGCTGTACGCACGTCAG ATGGAGATCCGAGGTGTGGACCTGGATGCTCCCTACTACAACTACATCATCTCCTTCACGGTGCCCGACATCGACAACGTCACAGTGCTA GACTACGATGCCCGCGAGCAGCGTGTGTACTGGTCTGACGTGCGGACACAGGCCATCAAGCGGGCCTTCATCAACGGCACAGGCGTGGAG ACAGTCGTCTCTGCAGACTTGCCAAATGCCCACGGGCTGGCTGTGGACTGGGTCTCCCGAAACCTGTTCTGGACAAGCTATGACACCAAT AAGAAGCAGATCAATGTGGCCCGGCTGGATGGCTCCTTCAAGAACGCAGTGGTGCAGGGCCTGGAGCAGCCCCATGGCCTTGTCGTCCAC CCTCTGCGTGGGAAGCTCTACTGGACCGATGGTGACAACATCAGCATGGCCAACATGGATGGCAGCAATCGCACCCTGCTCTTCAGTGGC CAGAAGGGCCCCGTGGGCCTGGCTATTGACTTCCCTGAAAGCAAACTCTACTGGATCAGCTCCGGGAACCATACCATCAACCGCTGCAAC CTGGATGGGAGTGGGCTGGAGGTCATCGATGCCATGCGGAGCCAGCTGGGCAAGGCCACCGCCCTGGCCATCATGGGGGACAAGCTGTGG TGGGCTGATCAGGTGTCGGAAAAGATGGGCACATGCAGCAAGGCTGACGGCTCGGGCTCCGTGGTCCTTCGGAACAGCACCACCCTGGTG ATGCACATGAAGGTCTATGACGAGAGCATCCAGCTGGACCATAAGGGCACCAACCCCTGCAGTGTCAACAACGGTGACTGCTCCCAGCTC TGCCTGCCCACGTCAGAGACGACCCGCTCCTGCATGTGCACAGCCGGCTATAGCCTCCGGAGTGGCCAGCAGGCCTGCGAGGGCGTAGGT TCCTTTCTCCTGTACTCTGTGCATGAGGGAATCAGGGGAATTCCCCTGGATCCCAATGACAAGTCAGATGCCCTGGTCCCAGTGTCCGGG ACCTCGCTGGCTGTCGGCATCGACTTCCACGCTGAAAATGACACCATCTACTGGGTGGACATGGGCCTGAGCACGATCAGCCGGGCCAAG CGGGACCAGACGTGGCGTGAAGACGTGGTGACCAATGGCATTGGCCGTGTGGAGGGCATTGCAGTGGACTGGATCGCAGGCAACATCTAC TGGACAGACCAGGGCTTTGATGTCATCGAGGTCGCCCGGCTCAATGGCTCCTTCCGCTACGTGGTGATCTCCCAGGGTCTAGACAAGCCC CGGGCCATCACCGTCCACCCGGAGAAAGGGTACTTGTTCTGGACTGAGTGGGGTCAGTATCCGCGTATTGAGCGGTCTCGGCTAGATGGC ACGGAGCGTGTGGTGCTGGTCAACGTCAGCATCAGCTGGCCCAACGGCATCTCAGTGGACTACCAGGATGGGAAGCTGTACTGGTGCGAT GCACGGACAGACAAGATTGAACGGATCGACCTGGAGACAGGTGAGAACCGCGAGGTGGTTCTGTCCAGCAACAACATGGACATGTTTTCA GTGTCTGTGTTTGAGGATTTCATCTACTGGAGTGACAGGACTCATGCCAACGGCTCTATCAAGCGCGGGAGCAAAGACAATGCCACAGAC TCCGTGCCCCTGCGAACCGGCATCGGCGTCCAGCTTAAAGACATCAAAGTCTTCAACCGGGACCGGCAGAAAGGCACCAACGTGTGCGCG GTGGCCAATGGCGGGTGCCAGCAGCTGTGCCTGTACCGGGGCCGTGGGCAGCGGGCCTGCGCCTGTGCCCACGGGATGCTGGCTGAAGAC GGAGCATCGTGCCGCGAGTATGCCGGCTACCTGCTCTACTCAGAGCGCACCATTCTCAAGAGTATCCACCTGTCGGATGAGCGCAACCTC AATGCGCCCGTGCAGCCCTTCGAGGACCCTGAGCACATGAAGAACGTCATCGCCCTGGCCTTTGACTACCGGGCAGGCACCTCTCCGGGC ACCCCCAATCGCATCTTCTTCAGCGACATCCACTTTGGGAACATCCAACAGATCAACGACGATGGCTCCAGGAGGATCACCATTGTGGAA AACGTGGGCTCCGTGGAAGGCCTGGCCTATCACCGTGGCTGGGACACTCTCTATTGGACAAGCTACACGACATCCACCATCACGCGCCAC ACAGTGGACCAGACCCGCCCAGGGGCCTTCGAGCGTGAGACCGTCATCACTATGTCTGGAGATGACCACCCACGGGCCTTCGTTTTGGAC GAGTGCCAGAACCTCATGTTCTGGACCAACTGGAATGAGCAGCATCCCAGCATCATGCGGGCGGCGCTCTCGGGAGCCAATGTCCTGACC CTTATCGAGAAGGACATCCGTACCCCCAATGGCCTGGCCATCGACCACCGTGCCGAGAAGCTCTACTTCTCTGACGCCACCCTGGACAAG ATCGAGCGGTGCGAGTATGACGGCTCCCACCGCTATGTGATCCTAAAGTCAGAGCCTGTCCACCCCTTCGGGCTGGCCGTGTATGGGGAG CACATTTTCTGGACTGACTGGGTGCGGCGGGCAGTGCAGCGGGCCAACAAGCACGTGGGCAGCAACATGAAGCTGCTGCGCGTGGACATC CCCCAGCAGCCCATGGGCATCATCGCCGTGGCCAACGACACCAACAGCTGTGAACTCTCTCCATGCCGAATCAACAACGGTGGCTGCCAG GACCTGTGTCTGCTCACTCACCAGGGCCATGTCAACTGCTCATGCCGAGGGGGCCGAATCCTCCAGGATGACCTCACCTGCCGAGCGGTG AATTCCTCTTGCCGAGCACAAGATGAGTTTGAGTGTGCCAATGGCGAGTGCATCAACTTCAGCCTGACCTGCGACGGCGTCCCCCACTGC AAGGACAAGTCCGATGAGAAGCCATCCTACTGCAACTCCCGCCGCTGCAAGAAGACTTTCCGGCAGTGCAGCAATGGGCGCTGTGTGTCC AACATGCTGTGGTGCAACGGGGCCGACGACTGTGGGGATGGCTCTGACGAGATCCCTTGCAACAAGACAGCCTGTGGTGTGGGCGAGTTC CGCTGCCGGGACGGGACCTGCATCGGGAACTCCAGCCGCTGCAACCAGTTTGTGGATTGTGAGGACGCCTCAGATGAGATGAACTGCAGT GCCACCGACTGCAGCAGCTACTTCCGCCTGGGCGTGAAGGGCGTGCTCTTCCAGCCCTGCGAGCGGACCTCACTCTGCTACGCACCCAGC TGGGTGTGTGATGGCGCCAATGACTGTGGGGACTACAGTGATGAGCGCGACTGCCCAGGTGTGAAACGCCCCAGATGCCCTCTGAATTAC TTCGCCTGCCCTAGTGGGCGCTGCATCCCCATGAGCTGGACGTGTGACAAAGAGGATGACTGTGAACATGGCGAGGACGAGACCCACTGC AACAAGTTCTGCTCAGAGGCCCAGTTTGAGTGCCAGAACCATCGCTGCATCTCCAAGCAGTGGCTGTGTGACGGCAGCGATGACTGTGGG GATGGCTCAGACGAGGCTGCTCACTGTGAAGGCAAGACGTGCGGCCCCTCCTCCTTCTCCTGCCCTGGCACCCACGTGTGCGTCCCCGAG CGCTGGCTCTGTGACGGTGACAAAGACTGTGCTGATGGTGCAGACGAGAGCATCGCAGCTGGTTGCTTGTACAACAGCACTTGTGACGAC CGTGAGTTCATGTGCCAGAACCGCCAGTGCATCCCCAAGCACTTCGTGTGTGACCACGACCGTGACTGTGCAGATGGCTCTGATGAGTCC CCCGAGTGTGAGTACCCGACCTGCGGCCCCAGTGAGTTCCGCTGTGCCAATGGGCGCTGTCTGAGCTCCCGCCAGTGGGAGTGTGATGGC GAGAATGACTGCCACGACCAGAGTGACGAGGCTCCCAAGAACCCACACTGCACCAGCCAAGAGCACAAGTGCAATGCCTCGTCACAGTTC CTGTGCAGCAGTGGGCGCTGTGTGGCTGAGGCACTGCTCTGCAACGGCCAGGATGACTGTGGCGACAGCTCGGACGAGCGTGGCTGCCAC ATCAATGAGTGTCTCAGCCGCAAGCTCAGTGGCTGCAGCCAGGACTGTGAGGACCTCAAGATCGGCTTCAAGTGCCGCTGTCGCCCTGGC TTCCGGCTGAAGGACGACGGCCGGACGTGTGCTGATGTGGACGAGTGCAGCACCACCTTCCCCTGCAGCCAGCGCTGCATCAACACTCAT GGCAGCTATAAGTGTCTGTGTGTGGAGGGCTATGCACCCCGCGGCGGCGACCCCCACAGCTGCAAGGCTGTGACTGACGAGGAACCGTTT CTGATCTTCGCCAACCGGTACTACCTGCGCAAGCTCAACCTGGACGGGTCCAACTACACGTTACTTAAGCAGGGCCTGAACAACGCCGTT GCCTTGGATTTTGACTACCGAGAGCAGATGATCTACTGGACAGATGTGACCACCCAGGGCAGCATGATCCGAAGGATGCACCTTAACGGG AGCAATGTGCAGGTCCTACACCGTACAGGCCTCAGCAACCCCGATGGGCTGGCTGTGGACTGGGTGGGTGGCAACCTGTACTGGTGCGAC AAAGGCCGGGACACCATCGAGGTGTCCAAGCTCAATGGGGCCTATCGGACGGTGCTGGTCAGCTCTGGCCTCCGTGAGCCCAGGGCTCTG GTGGTGGATGTGCAGAATGGGTACCTGTACTGGACAGACTGGGGTGACCATTCACTGATCGGCCGCATCGGCATGGATGGGTCCAGCCGC AGCGTCATCGTGGACACCAAGATCACATGGCCCAATGGCCTGACGCTGGACTATGTCACTGAGCGCATCTACTGGGCCGACGCCCGCGAG GACTACATTGAATTTGCCAGCCTGGATGGCTCCAATCGCCACGTTGTGCTGAGCCAGGACATCCCGCACATCTTTGCACTGACCCTGTTT GAGGACTACGTCTACTGGACCGACTGGGAAACAAAGTCCATTAACCGAGCCCACAAGACCACGGGCACCAACAAAACGCTCCTCATCAGC ACGCTGCACCGGCCCATGGACCTGCATGTCTTCCATGCCCTGCGCCAGCCAGACGTGCCCAATCACCCCTGCAAGGTCAACAATGGTGGC TGCAGCAACCTGTGCCTGCTGTCCCCCGGGGGAGGGCACAAATGTGCCTGCCCCACCAACTTCTACCTGGGCAGCGATGGGCGCACCTGT GTGTCCAACTGCACGGCTAGCCAGTTTGTATGCAAGAACGACAAGTGCATCCCCTTCTGGTGGAAGTGTGACACCGAGGACGACTGCGGG GACCACTCAGACGAGCCCCCGGACTGCCCTGAGTTCAAGTGCCGGCCCGGACAGTTCCAGTGCTCCACAGGTATCTGCACAAACCCTGCC TTCATCTGCGATGGCGACAATGACTGCCAGGACAACAGTGACGAGGCCAACTGTGACATCCACGTCTGCTTGCCCAGTCAGTTCAAATGC ACCAACACCAACCGCTGTATTCCCGGCATCTTCCGCTGCAATGGGCAGGACAACTGCGGAGATGGGGAGGATGAGAGGGACTGCCCCGAG GTGACCTGCGCCCCCAACCAGTTCCAGTGCTCCATTACCAAACGGTGCATCCCCCGGGTCTGGGTCTGCGACCGGGACAATGACTGTGTG GATGGCAGTGATGAGCCCGCCAACTGCACCCAGATGACCTGTGGTGTGGACGAGTTCCGCTGCAAGGATTCGGGCCGCTGCATCCCAGCG CGTTGGAAGTGTGACGGAGAGGATGACTGTGGGGATGGCTCGGATGAGCCCAAGGAAGAGTGTGATGAACGCACCTGTGAGCCATACCAG TTCCGCTGCAAGAACAACCGCTGCGTGCCCGGCCGCTGGCAGTGCGACTACGACAACGATTGCGGTGACAACTCCGATGAAGAGAGCTGC AACCGGTACCGGGAGTACCAGTGGATCGGACTCAACGACAGGACCATCGAAGGCGACTTCTTGTGGTCGGATGGCGTCCCCCTGCTCTAT GAGAACTGGAACCCTGGGCAGCCTGACAGCTACTTCCTGTCTGGAGAGAACTGCGTGGTCATGGTGTGGCATGATCAGGGACAATGGAGT GACGTGCCCTGCAACTACCACCTGTCCTACACCTGCAAGATGGGGCTGGTGTCCTGTGGGCCGCCACCGGAGCTGCCCCTGGCTCAAGTG TTCGGCCGCCCACGGCTGCGCTATGAGGTGGACACTGTGCTTCGCTACCGGTGCCGGGAAGGACTGGCCCAGCGCAATCTGCCGCTGATC CGATGCCAAGAGAACGGTCGTTGGGAGGCCCCCCAGATCTCCTGTGTGCCCAGAAGACCTGCCCGAGCTCTGCACCCAGAGGAGGACCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LRP1_ENST00000243077_chr12_57596320_+_BCAN_ENST00000329117_chr1_156627467_+_12098nt CAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGCTCCCCT ACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCTGTGAGC TTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGT CAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAG GAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCT TGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAA GACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGA CGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTG TGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTG CTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGG CAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTG TGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAA CTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTT CAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAA GGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACGTGGAACAGATGGCCATCGACTGGCTGACAGGCAACTTCTA CTTTGTGGATGACATCGATGATAGGATCTTTGTCTGCAACAGAAATGGGGACACATGTGTCACATTGCTAGACCTGGAACTCTACAACCC CAAGGGCATTGCCCTGGACCCTGCCATGGGGAAGGTGTTTTTCACTGACTATGGGCAGATCCCAAAGGTGGAACGCTGTGACATGGATGG GCAGAACCGCACCAAGCTCGTCGACAGCAAGATTGTGTTTCCTCATGGCATCACGCTGGACCTGGTCAGCCGCCTTGTCTACTGGGCAGA TGCCTATCTGGACTATATTGAAGTGGTGGACTATGAGGGCAAGGGCCGCCAGACCATCATCCAGGGCATCCTGATTGAGCACCTGTACGG CCTGACTGTGTTTGAGAATTATCTCTATGCCACCAACTCGGACAATGCCAATGCCCAGCAGAAGACGAGTGTGATCCGTGTGAACCGCTT TAACAGCACCGAGTACCAGGTTGTCACCCGGGTGGACAAGGGTGGTGCCCTCCACATCTACCACCAGAGGCGTCAGCCCCGAGTGAGGAG CCATGCCTGTGAAAACGACCAGTATGGGAAGCCGGGTGGCTGCTCTGACATCTGCCTGCTGGCCAACAGCCACAAGGCGCGGACCTGCCG CTGCCGTTCCGGCTTCAGCCTGGGCAGTGACGGGAAGTCATGCAAGAAGCCGGAGCATGAGCTGTTCCTCGTGTATGGCAAGGGCCGGCC AGGCATCATCCGGGGCATGGATATGGGGGCCAAGGTCCCGGATGAGCACATGATCCCCATTGAAAACCTCATGAACCCCCGAGCCCTGGA CTTCCACGCTGAGACCGGCTTCATCTACTTTGCCGACACCACCAGCTACCTCATTGGCCGCCAGAAGATTGATGGCACTGAGCGGGAGAC CATCCTGAAGGACGGCATCCACAATGTGGAGGGTGTGGCCGTGGACTGGATGGGAGACAATCTGTACTGGACGGACGATGGGCCCAAAAA GACAATCAGCGTGGCCAGGCTGGAGAAAGCTGCTCAGACCCGCAAGACTTTAATCGAGGGCAAAATGACACACCCCAGGGCTATTGTGGT GGATCCACTCAATGGGTGGATGTACTGGACAGACTGGGAGGAGGACCCCAAGGACAGTCGGCGTGGGCGGCTGGAGAGGGCGTGGATGGA TGGCTCACACCGAGACATCTTTGTCACCTCCAAGACAGTGCTTTGGCCCAATGGGCTAAGCCTGGACATCCCGGCTGGGCGCCTCTACTG GGTGGATGCCTTCTACGACCGCATCGAGACGATACTGCTCAATGGCACAGACCGGAAGATTGTGTATGAAGGTCCTGAGCTGAACCACGC CTTTGGCCTGTGTCACCATGGCAACTACCTCTTCTGGACTGAGTATCGGAGTGGCAGTGTCTACCGCTTGGAACGGGGTGTAGGAGGCGC ACCCCCCACTGTGACCCTTCTGCGCAGTGAGCGGCCCCCCATCTTTGAGATCCGAATGTATGATGCCCAGCAGCAGCAAGTTGGCACCAA CAAATGCCGGGTGAACAATGGCGGCTGCAGCAGCCTGTGCTTGGCCACCCCTGGGAGCCGCCAGTGCGCCTGTGCTGAGGACCAGGTGTT GGACGCAGACGGCGTCACTTGCTTGGCGAACCCATCCTACGTGCCTCCACCCCAGTGCCAGCCAGGCGAGTTTGCCTGTGCCAACAGCCG CTGCATCCAGGAGCGCTGGAAGTGTGACGGAGACAACGATTGCCTGGACAACAGTGATGAGGCCCCAGCCCTCTGCCATCAGCACACCTG CCCCTCGGACCGATTCAAGTGCGAGAACAACCGGTGCATCCCCAACCGCTGGCTCTGCGACGGGGACAATGACTGTGGGAACAGTGAAGA TGAGTCCAATGCCACTTGTTCAGCCCGCACCTGCCCCCCCAACCAGTTCTCCTGTGCCAGTGGCCGCTGCATCCCCATCTCCTGGACGTG TGATCTGGATGACGACTGTGGGGACCGCTCTGATGAGTCTGCTTCGTGTGCCTATCCCACCTGCTTCCCCCTGACTCAGTTTACCTGCAA CAATGGCAGATGTATCAACATCAACTGGAGATGCGACAATGACAATGACTGTGGGGACAACAGTGACGAAGCCGGCTGCAGCCACTCCTG TTCTAGCACCCAGTTCAAGTGCAACAGCGGGCGTTGCATCCCCGAGCACTGGACCTGCGATGGGGACAATGACTGCGGAGACTACAGTGA TGAGACACACGCCAACTGCACCAACCAGGCCACGAGGCCCCCTGGTGGCTGCCACACTGATGAGTTCCAGTGCCGGCTGGATGGACTATG CATCCCCCTGCGGTGGCGCTGCGATGGGGACACTGACTGCATGGACTCCAGCGATGAGAAGAGCTGTGAGGGAGTGACCCACGTCTGCGA TCCCAGTGTCAAGTTTGGCTGCAAGGACTCAGCTCGGTGCATCAGCAAAGCGTGGGTGTGTGATGGCGACAATGACTGTGAGGATAACTC GGACGAGGAGAACTGCGAGTCCCTGGCCTGCAGGCCACCCTCGCACCCTTGTGCCAACAACACCTCAGTCTGCCTGCCCCCTGACAAGCT GTGTGATGGCAACGACGACTGTGGCGACGGCTCAGATGAGGGCGAGCTCTGCGACCAGTGCTCTCTGAATAACGGTGGCTGCAGCCACAA CTGCTCAGTGGCACCTGGCGAAGGCATTGTGTGTTCCTGCCCTCTGGGCATGGAGCTGGGGCCCGACAACCACACCTGCCAGATCCAGAG CTACTGTGCCAAGCATCTCAAATGCAGCCAAAAGTGCGACCAGAACAAGTTCAGCGTGAAGTGCTCCTGCTACGAGGGCTGGGTCCTGGA ACCTGACGGCGAGAGCTGCCGCAGCCTGGACCCCTTCAAGCCGTTCATCATTTTCTCCAACCGCCATGAAATCCGGCGCATCGATCTTCA CAAAGGAGACTACAGCGTCCTGGTGCCCGGCCTGCGCAACACCATCGCCCTGGACTTCCACCTCAGCCAGAGCGCCCTCTACTGGACCGA CGTGGTGGAGGACAAGATCTACCGCGGGAAGCTGCTGGACAACGGAGCCCTGACTAGTTTCGAGGTGGTGATTCAGTATGGCCTGGCCAC ACCCGAGGGCCTGGCTGTAGACTGGATTGCAGGCAACATCTACTGGGTGGAGAGTAACCTGGATCAGATCGAGGTGGCCAAGCTGGATGG GACCCTCCGGACCACCCTGCTGGCCGGTGACATTGAGCACCCAAGGGCAATCGCACTGGATCCCCGGGATGGGATCCTGTTTTGGACAGA CTGGGATGCCAGCCTGCCCCGCATTGAGGCAGCCTCCATGAGTGGGGCTGGGCGCCGCACCGTGCACCGGGAGACCGGCTCTGGGGGCTG GCCCAACGGGCTCACCGTGGACTACCTGGAGAAGCGCATCCTTTGGATTGACGCCAGGTCAGATGCCATTTACTCAGCCCGTTACGACGG CTCTGGCCACATGGAGGTGCTTCGGGGACACGAGTTCCTGTCGCACCCGTTTGCAGTGACGCTGTACGGGGGGGAGGTCTACTGGACTGA CTGGCGAACAAACACACTGGCTAAGGCCAACAAGTGGACCGGCCACAATGTCACCGTGGTACAGAGGACCAACACCCAGCCCTTTGACCT GCAGGTGTACCACCCCTCCCGCCAGCCCATGGCTCCCAATCCCTGTGAGGCCAATGGGGGCCAGGGCCCCTGCTCCCACCTGTGTCTCAT CAACTACAACCGGACCGTGTCCTGCGCCTGCCCCCACCTCATGAAGCTCCACAAGGACAACACCACCTGCTATGAGTTTAAGAAGTTCCT GCTGTACGCACGTCAGATGGAGATCCGAGGTGTGGACCTGGATGCTCCCTACTACAACTACATCATCTCCTTCACGGTGCCCGACATCGA CAACGTCACAGTGCTAGACTACGATGCCCGCGAGCAGCGTGTGTACTGGTCTGACGTGCGGACACAGGCCATCAAGCGGGCCTTCATCAA CGGCACAGGCGTGGAGACAGTCGTCTCTGCAGACTTGCCAAATGCCCACGGGCTGGCTGTGGACTGGGTCTCCCGAAACCTGTTCTGGAC AAGCTATGACACCAATAAGAAGCAGATCAATGTGGCCCGGCTGGATGGCTCCTTCAAGAACGCAGTGGTGCAGGGCCTGGAGCAGCCCCA TGGCCTTGTCGTCCACCCTCTGCGTGGGAAGCTCTACTGGACCGATGGTGACAACATCAGCATGGCCAACATGGATGGCAGCAATCGCAC CCTGCTCTTCAGTGGCCAGAAGGGCCCCGTGGGCCTGGCTATTGACTTCCCTGAAAGCAAACTCTACTGGATCAGCTCCGGGAACCATAC CATCAACCGCTGCAACCTGGATGGGAGTGGGCTGGAGGTCATCGATGCCATGCGGAGCCAGCTGGGCAAGGCCACCGCCCTGGCCATCAT GGGGGACAAGCTGTGGTGGGCTGATCAGGTGTCGGAAAAGATGGGCACATGCAGCAAGGCTGACGGCTCGGGCTCCGTGGTCCTTCGGAA CAGCACCACCCTGGTGATGCACATGAAGGTCTATGACGAGAGCATCCAGCTGGACCATAAGGGCACCAACCCCTGCAGTGTCAACAACGG TGACTGCTCCCAGCTCTGCCTGCCCACGTCAGAGACGACCCGCTCCTGCATGTGCACAGCCGGCTATAGCCTCCGGAGTGGCCAGCAGGC CTGCGAGGGCGTAGGTTCCTTTCTCCTGTACTCTGTGCATGAGGGAATCAGGGGAATTCCCCTGGATCCCAATGACAAGTCAGATGCCCT GGTCCCAGTGTCCGGGACCTCGCTGGCTGTCGGCATCGACTTCCACGCTGAAAATGACACCATCTACTGGGTGGACATGGGCCTGAGCAC GATCAGCCGGGCCAAGCGGGACCAGACGTGGCGTGAAGACGTGGTGACCAATGGCATTGGCCGTGTGGAGGGCATTGCAGTGGACTGGAT CGCAGGCAACATCTACTGGACAGACCAGGGCTTTGATGTCATCGAGGTCGCCCGGCTCAATGGCTCCTTCCGCTACGTGGTGATCTCCCA GGGTCTAGACAAGCCCCGGGCCATCACCGTCCACCCGGAGAAAGGGTACTTGTTCTGGACTGAGTGGGGTCAGTATCCGCGTATTGAGCG GTCTCGGCTAGATGGCACGGAGCGTGTGGTGCTGGTCAACGTCAGCATCAGCTGGCCCAACGGCATCTCAGTGGACTACCAGGATGGGAA GCTGTACTGGTGCGATGCACGGACAGACAAGATTGAACGGATCGACCTGGAGACAGGTGAGAACCGCGAGGTGGTTCTGTCCAGCAACAA CATGGACATGTTTTCAGTGTCTGTGTTTGAGGATTTCATCTACTGGAGTGACAGGACTCATGCCAACGGCTCTATCAAGCGCGGGAGCAA AGACAATGCCACAGACTCCGTGCCCCTGCGAACCGGCATCGGCGTCCAGCTTAAAGACATCAAAGTCTTCAACCGGGACCGGCAGAAAGG CACCAACGTGTGCGCGGTGGCCAATGGCGGGTGCCAGCAGCTGTGCCTGTACCGGGGCCGTGGGCAGCGGGCCTGCGCCTGTGCCCACGG GATGCTGGCTGAAGACGGAGCATCGTGCCGCGAGTATGCCGGCTACCTGCTCTACTCAGAGCGCACCATTCTCAAGAGTATCCACCTGTC GGATGAGCGCAACCTCAATGCGCCCGTGCAGCCCTTCGAGGACCCTGAGCACATGAAGAACGTCATCGCCCTGGCCTTTGACTACCGGGC AGGCACCTCTCCGGGCACCCCCAATCGCATCTTCTTCAGCGACATCCACTTTGGGAACATCCAACAGATCAACGACGATGGCTCCAGGAG GATCACCATTGTGGAAAACGTGGGCTCCGTGGAAGGCCTGGCCTATCACCGTGGCTGGGACACTCTCTATTGGACAAGCTACACGACATC CACCATCACGCGCCACACAGTGGACCAGACCCGCCCAGGGGCCTTCGAGCGTGAGACCGTCATCACTATGTCTGGAGATGACCACCCACG GGCCTTCGTTTTGGACGAGTGCCAGAACCTCATGTTCTGGACCAACTGGAATGAGCAGCATCCCAGCATCATGCGGGCGGCGCTCTCGGG AGCCAATGTCCTGACCCTTATCGAGAAGGACATCCGTACCCCCAATGGCCTGGCCATCGACCACCGTGCCGAGAAGCTCTACTTCTCTGA CGCCACCCTGGACAAGATCGAGCGGTGCGAGTATGACGGCTCCCACCGCTATGTGATCCTAAAGTCAGAGCCTGTCCACCCCTTCGGGCT GGCCGTGTATGGGGAGCACATTTTCTGGACTGACTGGGTGCGGCGGGCAGTGCAGCGGGCCAACAAGCACGTGGGCAGCAACATGAAGCT GCTGCGCGTGGACATCCCCCAGCAGCCCATGGGCATCATCGCCGTGGCCAACGACACCAACAGCTGTGAACTCTCTCCATGCCGAATCAA CAACGGTGGCTGCCAGGACCTGTGTCTGCTCACTCACCAGGGCCATGTCAACTGCTCATGCCGAGGGGGCCGAATCCTCCAGGATGACCT CACCTGCCGAGCGGTGAATTCCTCTTGCCGAGCACAAGATGAGTTTGAGTGTGCCAATGGCGAGTGCATCAACTTCAGCCTGACCTGCGA CGGCGTCCCCCACTGCAAGGACAAGTCCGATGAGAAGCCATCCTACTGCAACTCCCGCCGCTGCAAGAAGACTTTCCGGCAGTGCAGCAA TGGGCGCTGTGTGTCCAACATGCTGTGGTGCAACGGGGCCGACGACTGTGGGGATGGCTCTGACGAGATCCCTTGCAACAAGACAGCCTG TGGTGTGGGCGAGTTCCGCTGCCGGGACGGGACCTGCATCGGGAACTCCAGCCGCTGCAACCAGTTTGTGGATTGTGAGGACGCCTCAGA TGAGATGAACTGCAGTGCCACCGACTGCAGCAGCTACTTCCGCCTGGGCGTGAAGGGCGTGCTCTTCCAGCCCTGCGAGCGGACCTCACT CTGCTACGCACCCAGCTGGGTGTGTGATGGCGCCAATGACTGTGGGGACTACAGTGATGAGCGCGACTGCCCAGGTGTGAAACGCCCCAG ATGCCCTCTGAATTACTTCGCCTGCCCTAGTGGGCGCTGCATCCCCATGAGCTGGACGTGTGACAAAGAGGATGACTGTGAACATGGCGA GGACGAGACCCACTGCAACAAGTTCTGCTCAGAGGCCCAGTTTGAGTGCCAGAACCATCGCTGCATCTCCAAGCAGTGGCTGTGTGACGG CAGCGATGACTGTGGGGATGGCTCAGACGAGGCTGCTCACTGTGAAGGCAAGACGTGCGGCCCCTCCTCCTTCTCCTGCCCTGGCACCCA CGTGTGCGTCCCCGAGCGCTGGCTCTGTGACGGTGACAAAGACTGTGCTGATGGTGCAGACGAGAGCATCGCAGCTGGTTGCTTGTACAA CAGCACTTGTGACGACCGTGAGTTCATGTGCCAGAACCGCCAGTGCATCCCCAAGCACTTCGTGTGTGACCACGACCGTGACTGTGCAGA TGGCTCTGATGAGTCCCCCGAGTGTGAGTACCCGACCTGCGGCCCCAGTGAGTTCCGCTGTGCCAATGGGCGCTGTCTGAGCTCCCGCCA GTGGGAGTGTGATGGCGAGAATGACTGCCACGACCAGAGTGACGAGGCTCCCAAGAACCCACACTGCACCAGCCAAGAGCACAAGTGCAA TGCCTCGTCACAGTTCCTGTGCAGCAGTGGGCGCTGTGTGGCTGAGGCACTGCTCTGCAACGGCCAGGATGACTGTGGCGACAGCTCGGA CGAGCGTGGCTGCCACATCAATGAGTGTCTCAGCCGCAAGCTCAGTGGCTGCAGCCAGGACTGTGAGGACCTCAAGATCGGCTTCAAGTG CCGCTGTCGCCCTGGCTTCCGGCTGAAGGACGACGGCCGGACGTGTGCTGATGTGGACGAGTGCAGCACCACCTTCCCCTGCAGCCAGCG CTGCATCAACACTCATGGCAGCTATAAGTGTCTGTGTGTGGAGGGCTATGCACCCCGCGGCGGCGACCCCCACAGCTGCAAGGCTGTGAC TGACGAGGAACCGTTTCTGATCTTCGCCAACCGGTACTACCTGCGCAAGCTCAACCTGGACGGGTCCAACTACACGTTACTTAAGCAGGG CCTGAACAACGCCGTTGCCTTGGATTTTGACTACCGAGAGCAGATGATCTACTGGACAGATGTGACCACCCAGGGCAGCATGATCCGAAG GATGCACCTTAACGGGAGCAATGTGCAGGTCCTACACCGTACAGGCCTCAGCAACCCCGATGGGCTGGCTGTGGACTGGGTGGGTGGCAA CCTGTACTGGTGCGACAAAGGCCGGGACACCATCGAGGTGTCCAAGCTCAATGGGGCCTATCGGACGGTGCTGGTCAGCTCTGGCCTCCG TGAGCCCAGGGCTCTGGTGGTGGATGTGCAGAATGGGTACCTGTACTGGACAGACTGGGGTGACCATTCACTGATCGGCCGCATCGGCAT GGATGGGTCCAGCCGCAGCGTCATCGTGGACACCAAGATCACATGGCCCAATGGCCTGACGCTGGACTATGTCACTGAGCGCATCTACTG GGCCGACGCCCGCGAGGACTACATTGAATTTGCCAGCCTGGATGGCTCCAATCGCCACGTTGTGCTGAGCCAGGACATCCCGCACATCTT TGCACTGACCCTGTTTGAGGACTACGTCTACTGGACCGACTGGGAAACAAAGTCCATTAACCGAGCCCACAAGACCACGGGCACCAACAA AACGCTCCTCATCAGCACGCTGCACCGGCCCATGGACCTGCATGTCTTCCATGCCCTGCGCCAGCCAGACGTGCCCAATCACCCCTGCAA GGTCAACAATGGTGGCTGCAGCAACCTGTGCCTGCTGTCCCCCGGGGGAGGGCACAAATGTGCCTGCCCCACCAACTTCTACCTGGGCAG CGATGGGCGCACCTGTGTGTCCAACTGCACGGCTAGCCAGTTTGTATGCAAGAACGACAAGTGCATCCCCTTCTGGTGGAAGTGTGACAC CGAGGACGACTGCGGGGACCACTCAGACGAGCCCCCGGACTGCCCTGAGTTCAAGTGCCGGCCCGGACAGTTCCAGTGCTCCACAGGTAT CTGCACAAACCCTGCCTTCATCTGCGATGGCGACAATGACTGCCAGGACAACAGTGACGAGGCCAACTGTGACATCCACGTCTGCTTGCC CAGTCAGTTCAAATGCACCAACACCAACCGCTGTATTCCCGGCATCTTCCGCTGCAATGGGCAGGACAACTGCGGAGATGGGGAGGATGA GAGGGACTGCCCCGAGGTGACCTGCGCCCCCAACCAGTTCCAGTGCTCCATTACCAAACGGTGCATCCCCCGGGTCTGGGTCTGCGACCG GGACAATGACTGTGTGGATGGCAGTGATGAGCCCGCCAACTGCACCCAGATGACCTGTGGTGTGGACGAGTTCCGCTGCAAGGATTCGGG CCGCTGCATCCCAGCGCGTTGGAAGTGTGACGGAGAGGATGACTGTGGGGATGGCTCGGATGAGCCCAAGGAAGAGTGTGATGAACGCAC CTGTGAGCCATACCAGTTCCGCTGCAAGAACAACCGCTGCGTGCCCGGCCGCTGGCAGTGCGACTACGACAACGATTGCGGTGACAACTC CGATGAAGAGAGCTGCAACCGGTACCGGGAGTACCAGTGGATCGGACTCAACGACAGGACCATCGAAGGCGACTTCTTGTGGTCGGATGG CGTCCCCCTGCTCTATGAGAACTGGAACCCTGGGCAGCCTGACAGCTACTTCCTGTCTGGAGAGAACTGCGTGGTCATGGTGTGGCATGA TCAGGGACAATGGAGTGACGTGCCCTGCAACTACCACCTGTCCTACACCTGCAAGATGGGGCTGGTGTCCTGTGGGCCGCCACCGGAGCT GCCCCTGGCTCAAGTGTTCGGCCGCCCACGGCTGCGCTATGAGGTGGACACTGTGCTTCGCTACCGGTGCCGGGAAGGACTGGCCCAGCG CAATCTGCCGCTGATCCGATGCCAAGAGAACGGTCGTTGGGAGGCCCCCCAGATCTCCTGTGTGCCCAGAAGACCTGCCCGAGCTCTGCA CCCAGAGGAGGACCCAGAAGGACGTCAGGGGAGGCTACTGGGACGCTGGAAGGCGCTGTTGATCCCCCCTTCCAGCCCCATGCCAGGTCC CTAGGGGGCAAGGCCTTGAACACTGCCGGCCACAGCACTGCCCTGTCACCCAAATTTTCCCTCACACCCTGCGCTCCCGCCACCACAGGA AGTGACAACATGACGAGGGGTGGTACTGGAGTCCAGGTGACAGTTCCTGAAGGGGCTTCTGGGAAATACCTAGGAGGCTCCAGCCCAGCC CAGGCCCTCTCCCCCTACCCTGGGCACCAGATCTTCCATCAGGGCCGGAGTAAATCCCTAAGTGCCTCAACTGCCCTCTCCCTGGCAGCC ATCTTGTCCCCTCTATTCCTCTAGGGAGCACTGTGCCCACTCTTTCTGGGTTTTCCAAGGGAATGGGCTTGCAGGATGGAGTGTCTGTAA |
Top |
FusionGenePPI for LRP1_BCAN |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LRP1 | SERPINE1, CANX, CALR, PDIA2, MMP14, KAT5, CALCR, SHC1, THBS1, GIPC1, MAPK8IP1, DLG4, MAPK8IP2, SYNJ2BP, NOS1AP, SCN3A, APBA2, DAB1, ITGB1BP1, ANAPC10, A2M, PDGFB, SRC, DAB2, MDK, F8, GULP1, PLAUR, PLAT, F9, LRPAP1, LPL, LIPC, SNX17, APBB1, USP3, CACNA1A, APOE, RIC8B, CC2D1A, SNRNP70, ANKS1B, PID1, HNRNPDL, MAPRE1, FBXO6, CUBN, CHFR, SKIL, RANBP9, APP, COPS5, EGFR, ZFP41, DIAPH1, FOXB1, KCTD18, INTS6, TNKS2, TNKS, FOXF2, BCKDHB, TUBB8, SAMD1, TUBA4A, TUBB3, LOXL2, MTG2, SLC25A6, SLC25A30, GATB, SMOC1, C17orf80, GSG2, NME4, HARS2, TUBA1A, TUBB4A, SLC25A23, LCOR, CCRN4L, FAM115A, SLC25A25, MTO1, C1orf85, PC, PTGES2, SLC26A6, GFPT2, GFPT1, HSPA5, RPL23, TUBB2A, NPC2, MTPAP, TUBB4B, RPUSD3, GNB2, NPRL3, FAM132B, ERAL1, GCNT1, TUBB2B, PTCD2, SENP1, MAP2K7, RTEL1, LGALS9 | BCAN | FBLN2, MMP1, MMP2, MMP3, MMP7, MMP8, MMP10, MMP13, FBXO11, VCAN, ULK3, REPIN1, CCNYL1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LRP1_BCAN |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | LRP1 | Q07954 | DB00031 | Tenecteplase | Prolow-density lipoprotein receptor-related protein 1 | biotech | approved |
| Hgene | LRP1 | Q07954 | DB00025 | Antihemophilic factor, human recombinant | Prolow-density lipoprotein receptor-related protein 1 | biotech | approved|investigational |
| Hgene | LRP1 | Q07954 | DB00100 | Coagulation Factor IX (Recombinant) | Prolow-density lipoprotein receptor-related protein 1 | biotech | approved|investigational |
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RelatedDiseases for LRP1_BCAN |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | LRP1 | C0036341 | Schizophrenia | 1 | CTD_human |
| Hgene | LRP1 | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Hgene | LRP1 | C0149931 | Migraine Disorders | 1 | CTD_human |
| Hgene | LRP1 | C0338480 | Common Migraine | 1 | CTD_human |
| Hgene | LRP1 | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
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