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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 19898

FusionGeneSummary for LMNA_LMNA

check button Fusion gene summary
Fusion gene informationFusion gene name: LMNA_LMNA
Fusion gene ID: 19898
HgeneTgene
Gene symbol

LMNA

LMNA

Gene ID

4000

4000

Gene namelamin A/Clamin A/C
SynonymsCDCD1|CDDC|CMD1A|CMT2B1|EMD2|FPL|FPLD|FPLD2|HGPS|IDC|LDP1|LFP|LGMD1B|LMN1|LMNC|LMNL1|MADA|PRO1CDCD1|CDDC|CMD1A|CMT2B1|EMD2|FPL|FPLD|FPLD2|HGPS|IDC|LDP1|LFP|LGMD1B|LMN1|LMNC|LMNL1|MADA|PRO1
Cytomap

1q22

1q22

Type of geneprotein-codingprotein-coding
Descriptionlamin70 kDa laminlamin A/C-like 1mandibuloacral dysplasia type Aprelamin-A/Crenal carcinoma antigen NY-REN-32lamin70 kDa laminlamin A/C-like 1mandibuloacral dysplasia type Aprelamin-A/Crenal carcinoma antigen NY-REN-32
Modification date2018052320180523
UniProtAcc

P02545

P02545

Ensembl transtripts involved in fusion geneENST00000368301, ENST00000361308, 
ENST00000347559, ENST00000368300, 
ENST00000368299, ENST00000448611, 
ENST00000368297, ENST00000473598, 
ENST00000392353, ENST00000496738, 
ENST00000368301, ENST00000361308, 
ENST00000347559, ENST00000368300, 
ENST00000368299, ENST00000448611, 
ENST00000368297, ENST00000473598, 
ENST00000392353, ENST00000496738, 
Fusion gene scores* DoF score11 X 12 X 6=7929 X 11 X 3=297
# samples 1411
** MAII scorelog2(14/792*10)=-2.50007360313464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(11/297*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LMNA [Title/Abstract] AND LMNA [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTranscription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLMNA

GO:0090343

positive regulation of cell aging

20458013

TgeneLMNA

GO:0090343

positive regulation of cell aging

20458013


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1AA852769LMNAchr1

156104673

-LMNAchr1

156105753

+
ChiTaRS3.1AW793883LMNAchr1

156099550

-LMNAchr1

156099391

+
ChiTaRS3.1AI184403LMNAchr1

156108918

-LMNAchr1

156109572

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000368301ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368301ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000368301ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000361308ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000361308ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000347559ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000347559ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368300ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000368300ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368299ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000368299ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000448611ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000448611ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000368297ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000368297ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000473598ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000473598ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
In-frameENST00000392353ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
5CDS-3UTRENST00000392353ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000368301LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000361308LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000347559LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000368300LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000368299LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000448611LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000368297LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000473598LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3CDSENST00000496738ENST00000392353LMNAchr1

156104673

-LMNAchr1

156105753

+
3UTR-3UTRENST00000496738ENST00000496738LMNAchr1

156104673

-LMNAchr1

156105753

+
intron-intronENST00000368301ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000361308ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000347559ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368300ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368299ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000448611ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368297ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000368299LMNAchr1

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-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

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intron-intronENST00000473598ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000473598ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000392353ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000368301LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000361308LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000347559LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000368300LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000368299LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000448611LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000368297LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000473598LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000392353LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000496738ENST00000496738LMNAchr1

156099550

-LMNAchr1

156099391

+
intron-intronENST00000368301ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000368301ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000368301ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368301ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000361308ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000361308ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000361308ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000347559ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000347559ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000347559ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000368300ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000368300ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368300ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000368299ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000368299ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000368299ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000448611ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000448611ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000448611ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000368297ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000368297ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000368297ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000473598ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000473598ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000473598ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000392353ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-3UTRENST00000392353ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
intron-intronENST00000392353ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000368301LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000361308LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000496738ENST00000347559LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-3UTRENST00000496738ENST00000368300LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000368299LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000448611LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000368297LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000473598LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000392353LMNAchr1

156108918

-LMNAchr1

156109572

-
3UTR-intronENST00000496738ENST00000496738LMNAchr1

156108918

-LMNAchr1

156109572

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Top

FusionProtFeatures for LMNA_LMNA


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LMNA

P02545

LMNA

P02545


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+01131_387-83635DomainIF rod
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+011428_545-83635DomainLTD
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+01031_387-83573DomainIF rod
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+010428_545-83573DomainLTD
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+01231_387-71665DomainIF rod
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+012428_545-71665DomainLTD
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+01331_387-214573DomainIF rod
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+013428_545-214573DomainLTD
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+01331_387-15575DomainIF rod
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+013428_545-15575DomainLTD
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+011417_422-83635MotifNuclear localization signal
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+010417_422-83573MotifNuclear localization signal
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+012417_422-71665MotifNuclear localization signal
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+013417_422-214573MotifNuclear localization signal
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+013417_422-15575MotifNuclear localization signal
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+0111_33-83635RegionNote=Head
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+011219_242-83635RegionNote=Linker 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+011243_383-83635RegionNote=Coil 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+01134_70-83635RegionNote=Coil 1A
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+011384_664-83635RegionNote=Tail
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+01171_80-83635RegionNote=Linker 1
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+01181_218-83635RegionNote=Coil 1B
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+0101_33-83573RegionNote=Head
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+010219_242-83573RegionNote=Linker 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+010243_383-83573RegionNote=Coil 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+01034_70-83573RegionNote=Coil 1A
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+010384_664-83573RegionNote=Tail
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+01071_80-83573RegionNote=Linker 1
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+01081_218-83573RegionNote=Coil 1B
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+0121_33-71665RegionNote=Head
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+012219_242-71665RegionNote=Linker 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+012243_383-71665RegionNote=Coil 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+01234_70-71665RegionNote=Coil 1A
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+012384_664-71665RegionNote=Tail
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+01271_80-71665RegionNote=Linker 1
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+01281_218-71665RegionNote=Coil 1B
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+0131_33-214573RegionNote=Head
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+013219_242-214573RegionNote=Linker 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+013243_383-214573RegionNote=Coil 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+01334_70-214573RegionNote=Coil 1A
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+013384_664-214573RegionNote=Tail
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+01371_80-214573RegionNote=Linker 1
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+01381_218-214573RegionNote=Coil 1B
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+0131_33-15575RegionNote=Head
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+013219_242-15575RegionNote=Linker 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+013243_383-15575RegionNote=Coil 2
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+01334_70-15575RegionNote=Coil 1A
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+013384_664-15575RegionNote=Tail
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+01371_80-15575RegionNote=Linker 1
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+01381_218-15575RegionNote=Coil 1B

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+11131_387-83635DomainIF rod
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+111428_545-83635DomainLTD
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+11031_387-83573DomainIF rod
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+110428_545-83573DomainLTD
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+11231_387-71665DomainIF rod
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+112428_545-71665DomainLTD
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+11331_387-214573DomainIF rod
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+113428_545-214573DomainLTD
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+11331_387-15575DomainIF rod
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+113428_545-15575DomainLTD
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+111417_422-83635MotifNuclear localization signal
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+110417_422-83573MotifNuclear localization signal
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+112417_422-71665MotifNuclear localization signal
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+113417_422-214573MotifNuclear localization signal
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+113417_422-15575MotifNuclear localization signal
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+1111_33-83635RegionNote=Head
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+111219_242-83635RegionNote=Linker 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+111243_383-83635RegionNote=Coil 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+11134_70-83635RegionNote=Coil 1A
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+111384_664-83635RegionNote=Tail
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+11171_80-83635RegionNote=Linker 1
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+11181_218-83635RegionNote=Coil 1B
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+1101_33-83573RegionNote=Head
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+110219_242-83573RegionNote=Linker 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+110243_383-83573RegionNote=Coil 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+11034_70-83573RegionNote=Coil 1A
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+110384_664-83573RegionNote=Tail
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+11071_80-83573RegionNote=Linker 1
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+11081_218-83573RegionNote=Coil 1B
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+1121_33-71665RegionNote=Head
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+112219_242-71665RegionNote=Linker 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+112243_383-71665RegionNote=Coil 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+11234_70-71665RegionNote=Coil 1A
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+112384_664-71665RegionNote=Tail
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+11271_80-71665RegionNote=Linker 1
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+11281_218-71665RegionNote=Coil 1B
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+1131_33-214573RegionNote=Head
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+113219_242-214573RegionNote=Linker 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+113243_383-214573RegionNote=Coil 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+11334_70-214573RegionNote=Coil 1A
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+113384_664-214573RegionNote=Tail
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+11371_80-214573RegionNote=Linker 1
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+11381_218-214573RegionNote=Coil 1B
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+1131_33-15575RegionNote=Head
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+113219_242-15575RegionNote=Linker 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+113243_383-15575RegionNote=Coil 2
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+11334_70-15575RegionNote=Coil 1A
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+113384_664-15575RegionNote=Tail
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+11371_80-15575RegionNote=Linker 1
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+11381_218-15575RegionNote=Coil 1B


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FusionGeneSequence for LMNA_LMNA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for LMNA_LMNA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneLMNAchr1:156104673chr1:156105753ENST00000347559+0111_130-83635MLIP
TgeneLMNAchr1:156104673chr1:156105753ENST00000361308+0101_130-83573MLIP
TgeneLMNAchr1:156104673chr1:156105753ENST00000368300+0121_130-71665MLIP
TgeneLMNAchr1:156104673chr1:156105753ENST00000368301+0131_130-214573MLIP
TgeneLMNAchr1:156104673chr1:156105753ENST00000448611+0131_130-15575MLIP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneLMNAchr1:156104673chr1:156105753ENST00000347559+1111_130-83635MLIP
HgeneLMNAchr1:156104673chr1:156105753ENST00000361308+1101_130-83573MLIP
HgeneLMNAchr1:156104673chr1:156105753ENST00000368300+1121_130-71665MLIP
HgeneLMNAchr1:156104673chr1:156105753ENST00000368301+1131_130-214573MLIP
HgeneLMNAchr1:156104673chr1:156105753ENST00000448611+1131_130-15575MLIP


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LMNA_LMNA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LMNA_LMNA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLMNAC0410190Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)19ORPHANET;UNIPROT
HgeneLMNAC1449563Cardiomyopathy, Familial Idiopathic17ORPHANET;UNIPROT
HgeneLMNAC0033300Progeria14CTD_human;ORPHANET;UNIPROT
HgeneLMNAC1720860Familial Partial Lipodystrophy, Type 210ORPHANET;UNIPROT
HgeneLMNAC1834653MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1B (disorder)7CTD_human;ORPHANET;UNIPROT
HgeneLMNAC0432291Mandibuloacral dysostosis5CTD_human;ORPHANET;UNIPROT
HgeneLMNAC0271694Familial partial lipodystrophy4CTD_human
HgeneLMNAC0007193Cardiomyopathy, Dilated3CTD_human;HPO
HgeneLMNAC0796031Malouf syndrome3ORPHANET;UNIPROT
HgeneLMNAC2750035Emery-Dreifuss Muscular Dystrophy 32UNIPROT
HgeneLMNAC2750785MUSCULAR DYSTROPHY, CONGENITAL, LMNA-RELATED (disorder)2CTD_human;ORPHANET;UNIPROT
HgeneLMNAC0016508Congenital Foot Deformity1CTD_human
HgeneLMNAC0018566Congenital Hand Deformities1CTD_human
HgeneLMNAC0018794Heart Block1CTD_human
HgeneLMNAC0032460Polycystic Ovary Syndrome1CTD_human;HPO
HgeneLMNAC0036420Localized scleroderma1CTD_human
HgeneLMNAC0037188Sinoatrial Block1CTD_human
HgeneLMNAC0042514Tachycardia, Ventricular1CTD_human
HgeneLMNAC0085298Sudden Cardiac Death1CTD_human;HPO
HgeneLMNAC0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneLMNAC0376634Craniofacial Abnormalities1CTD_human
HgeneLMNAC0410189Muscular Dystrophy, Emery-Dreifuss1CTD_human
HgeneLMNAC0686353Muscular Dystrophies, Limb-Girdle1CTD_human;HPO
HgeneLMNAC1136321HIV-Associated Lipodystrophy Syndrome1CTD_human
HgeneLMNAC1854154Charcot-Marie-Tooth disease, Type 2B11CTD_human;ORPHANET;UNIPROT
TgeneLMNAC0410190Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)19ORPHANET;UNIPROT
TgeneLMNAC1449563Cardiomyopathy, Familial Idiopathic17ORPHANET;UNIPROT
TgeneLMNAC0033300Progeria14CTD_human;ORPHANET;UNIPROT
TgeneLMNAC1720860Familial Partial Lipodystrophy, Type 210ORPHANET;UNIPROT
TgeneLMNAC1834653MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1B (disorder)7CTD_human;ORPHANET;UNIPROT
TgeneLMNAC0432291Mandibuloacral dysostosis5CTD_human;ORPHANET;UNIPROT
TgeneLMNAC0271694Familial partial lipodystrophy4CTD_human
TgeneLMNAC0007193Cardiomyopathy, Dilated3CTD_human;HPO
TgeneLMNAC0796031Malouf syndrome3ORPHANET;UNIPROT
TgeneLMNAC2750035Emery-Dreifuss Muscular Dystrophy 32UNIPROT
TgeneLMNAC2750785MUSCULAR DYSTROPHY, CONGENITAL, LMNA-RELATED (disorder)2CTD_human;ORPHANET;UNIPROT
TgeneLMNAC0016508Congenital Foot Deformity1CTD_human
TgeneLMNAC0018566Congenital Hand Deformities1CTD_human
TgeneLMNAC0018794Heart Block1CTD_human
TgeneLMNAC0032460Polycystic Ovary Syndrome1CTD_human;HPO
TgeneLMNAC0036420Localized scleroderma1CTD_human
TgeneLMNAC0037188Sinoatrial Block1CTD_human
TgeneLMNAC0042514Tachycardia, Ventricular1CTD_human
TgeneLMNAC0085298Sudden Cardiac Death1CTD_human;HPO
TgeneLMNAC0152013Adenocarcinoma of lung (disorder)1CTD_human
TgeneLMNAC0376634Craniofacial Abnormalities1CTD_human
TgeneLMNAC0410189Muscular Dystrophy, Emery-Dreifuss1CTD_human
TgeneLMNAC0686353Muscular Dystrophies, Limb-Girdle1CTD_human;HPO
TgeneLMNAC1136321HIV-Associated Lipodystrophy Syndrome1CTD_human
TgeneLMNAC1854154Charcot-Marie-Tooth disease, Type 2B11CTD_human;ORPHANET;UNIPROT