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Fusion gene ID: 19780 |
FusionGeneSummary for LINC00668_SLC9B1 |
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Fusion gene information | Fusion gene name: LINC00668_SLC9B1 | Fusion gene ID: 19780 | Hgene | Tgene | Gene symbol | LINC00668 | SLC9B1 | Gene ID | 400643 | 150159 |
Gene name | long intergenic non-protein coding RNA 668 | solute carrier family 9 member B1 | |
Synonyms | - | NHA1|NHEDC1 | |
Cytomap | 18p11.31 | 4q24 | |
Type of gene | ncRNA | protein-coding | |
Description | - | sodium/hydrogen exchanger 9B1NHE domain-containing protein 1Na(+)/H(+) exchanger-like domain-containing protein 1sodium/hydrogen exchanger-like domain-containing protein 1solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member | |
Modification date | 20180329 | 20180523 | |
UniProtAcc | Q4ZJI4 | ||
Ensembl transtripts involved in fusion gene | ENST00000580197, | ENST00000394789, ENST00000296422, ENST00000512651, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
# samples | 2 | 2 | |
** MAII score | log2(2/1*10)=4.32192809488736 | log2(2/1*10)=4.32192809488736 | |
Context | PubMed: LINC00668 [Title/Abstract] AND SLC9B1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AI970491 | LINC00668 | chr18 | 6925664 | + | SLC9B1 | chr4 | 103936016 | + | ||
ChiTaRS3.1 | BE464457 | LINC00668 | chr18 | 6925664 | + | SLC9B1 | chr4 | 103936016 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000580197 | ENST00000394789 | LINC00668 | chr18 | 6925664 | + | SLC9B1 | chr4 | 103936016 | + |
intron-intron | ENST00000580197 | ENST00000296422 | LINC00668 | chr18 | 6925664 | + | SLC9B1 | chr4 | 103936016 | + |
intron-intron | ENST00000580197 | ENST00000512651 | LINC00668 | chr18 | 6925664 | + | SLC9B1 | chr4 | 103936016 | + |
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FusionProtFeatures for LINC00668_SLC9B1 |
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Hgene | Tgene |
LINC00668 | SLC9B1 |
Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Sperm-specific Na(+)/H(+) exchanger involved inintracellular pH regulation of spermatozoa. Involved in spermmotility and fertility. {ECO:0000250|UniProtKB:Q8C0X2}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for LINC00668_SLC9B1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for LINC00668_SLC9B1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LINC00668_SLC9B1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LINC00668_SLC9B1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |