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Fusion gene ID: 1974 |
FusionGeneSummary for ANXA10_FAM198B |
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Fusion gene information | Fusion gene name: ANXA10_FAM198B | Fusion gene ID: 1974 | Hgene | Tgene | Gene symbol | ANXA10 | FAM198B | Gene ID | 11199 | 51313 |
Gene name | annexin A10 | family with sequence similarity 198 member B | |
Synonyms | ANX14 | AD021|AD036|C4orf18|ENED | |
Cytomap | 4q32.3 | 4q32.1 | |
Type of gene | protein-coding | protein-coding | |
Description | annexin A10annexin 14annexin-10 | protein FAM198Bexpressed in nerve and epithelium during development | |
Modification date | 20180519 | 20180403 | |
UniProtAcc | Q9UJ72 | Q6UWH4 | |
Ensembl transtripts involved in fusion gene | ENST00000359299, | ENST00000585682, ENST00000296530, ENST00000393807, ENST00000589306, ENST00000592057, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 2=8 |
# samples | 1 | 2 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/8*10)=1.32192809488736 | |
Context | PubMed: ANXA10 [Title/Abstract] AND FAM198B [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | RV | BRCA | TCGA-BH-A1FL-01A | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000359299 | ENST00000585682 | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
Frame-shift | ENST00000359299 | ENST00000296530 | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
Frame-shift | ENST00000359299 | ENST00000393807 | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
5CDS-5UTR | ENST00000359299 | ENST00000589306 | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
5CDS-intron | ENST00000359299 | ENST00000592057 | ANXA10 | chr4 | 169049316 | + | FAM198B | chr4 | 159052164 | - |
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FusionProtFeatures for ANXA10_FAM198B |
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Hgene | Tgene |
ANXA10 | FAM198B |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ANXA10_FAM198B |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ANXA10_FAM198B |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
ANXA10 | BAG3, EDC3 | FAM198B |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ANXA10_FAM198B |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANXA10_FAM198B |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Tgene | FAM198B | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |