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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 19725

FusionGeneSummary for LIMCH1_HOPX

check button Fusion gene summary
Fusion gene informationFusion gene name: LIMCH1_HOPX
Fusion gene ID: 19725
HgeneTgene
Gene symbol

LIMCH1

HOPX

Gene ID

22998

84525

Gene nameLIM and calponin homology domains 1HOP homeobox
SynonymsLIMCH1A|LMO7BCAMEO|HOD|HOP|LAGY|NECC1|OB1|SMAP31|TOTO
Cytomap

4p13

4q12

Type of geneprotein-codingprotein-coding
DescriptionLIM and calponin homology domains-containing protein 1homeodomain-only proteinlung cancer-associated Y proteinnot expressed in choriocarcinoma clone 1odd homeobox protein 1
Modification date2018051920180523
UniProtAcc

Q9UPQ0

Q9BPY8

Ensembl transtripts involved in fusion geneENST00000513024, ENST00000509638, 
ENST00000508501, ENST00000512946, 
ENST00000313860, ENST00000512632, 
ENST00000512820, ENST00000503057, 
ENST00000511496, ENST00000514096, 
ENST00000509277, ENST00000396595, 
ENST00000381753, ENST00000509454, 
ENST00000515785, 		ENST00000554144, 
ENST00000420433, ENST00000556376, 
ENST00000381260, ENST00000337881, 
ENST00000605395, ENST00000508121, 
ENST00000503639, ENST00000553379, 
ENST00000381255, ENST00000317745, 
ENST00000555760, ENST00000556614, 
Fusion gene scores* DoF score10 X 8 X 6=4804 X 3 X 3=36
# samples 135
** MAII scorelog2(13/480*10)=-1.88452278258006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/36*10)=0.473931188332412
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LIMCH1 [Title/Abstract] AND HOPX [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneHOPX

GO:0001829

trophectodermal cell differentiation

17576768

TgeneHOPX

GO:0045596

negative regulation of cell differentiation

17576768

TgeneHOPX

GO:0051131

chaperone-mediated protein complex assembly

10811660


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDPRADTCGA-J4-A67T-01ALIMCH1chr4

41362953

+HOPXchr4

57522178

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000513024ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000513024ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000513024ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000513024ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000513024ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-3CDSENST00000509638ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-3CDSENST00000509638ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-intronENST00000509638ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-intronENST00000509638ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5UTR-5UTRENST00000509638ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000508501ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000508501ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000508501ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000508501ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000508501ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512946ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512946ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512946ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512946ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512946ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000313860ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000313860ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000313860ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000313860ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000313860ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512632ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512632ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512632ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512632ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512632ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512820ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
In-frameENST00000512820ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512820ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-intronENST00000512820ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
5CDS-5UTRENST00000512820ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000503057ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000503057ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000503057ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000503057ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000503057ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000511496ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000511496ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000511496ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000511496ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000511496ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000514096ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000514096ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000514096ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000514096ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000514096ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000509277ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000509277ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000509277ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000509277ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509277ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000396595ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000396595ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000396595ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000396595ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000396595ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000381753ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000381753ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000381753ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000381753ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000381753ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000509454ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000509454ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000509454ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000509454ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000509454ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000515785ENST00000554144LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-3CDSENST00000515785ENST00000420433LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000556376LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000381260LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000337881LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000515785ENST00000605395LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-intronENST00000515785ENST00000508121LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000503639LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000553379LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000381255LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000317745LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000555760LIMCH1chr4

41362953

+HOPXchr4

57522178

-
intron-5UTRENST00000515785ENST00000556614LIMCH1chr4

41362953

+HOPXchr4

57522178

-

Top

FusionProtFeatures for LIMCH1_HOPX


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LIMCH1

Q9UPQ0

HOPX

Q9BPY8

Atypical homeodomain protein which does not bind DNA andis required to modulate cardiac growth and development. Acts viaits interaction with SRF, thereby modulating the expression ofSRF-dependent cardiac-specific genes and cardiac development.Prevents SRF-dependent transcription either by inhibiting SRFbinding to DNA or by recruiting histone deacetylase (HDAC)proteins that prevent transcription by SRF. Overexpression causescardiac hypertrophy (By similarity). May act as a tumorsuppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperoneproteins and assists in chaperone-mediated protein refolding(PubMed:27708256). {ECO:0000250|UniProtKB:Q8R1H0,ECO:0000269|PubMed:27708256}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for LIMCH1_HOPX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_131aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS

>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_110aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_131aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_110aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_131aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_110aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_131aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_110aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_131aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_110aa
MACPALGLEALQPLQPEPPPEPAFSEAQKWIERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_393nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCC
AGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCT

>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_330nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGC

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_393nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCC
AGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCT

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_330nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGC

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_393nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCC
AGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCT

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_330nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGC

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_393nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCC
AGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCT

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_330nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGC

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_393nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCC
AGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCT

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_330nt
ATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGG
ATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTC
GACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_1247nt
GGCGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTC
AGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCG
CGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCA
TCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCCAGGAGCAAAATATGGCACCCAGAAAGTAGCCCCC
AAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCTCTACTGCCGCCCCAGTGTAAAGAAATGGTTTAAG
CAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTT
CACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCT
GTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTG
TGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTG
CTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGG
GAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGG
TGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACT
CCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTG

>In-frame_LIMCH1_ENST00000508501_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_1117nt
GGCGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTC
AGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCG
CGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCA
TCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCT
CAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAA
CCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAAT
GTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGC
ATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAA
TCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTT
CCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAAT
ATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCAC
CAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTAAAATGATATT

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_1247nt
GGCGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTC
AGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCG
CGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCA
TCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCCAGGAGCAAAATATGGCACCCAGAAAGTAGCCCCC
AAAGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCTCTACTGCCGCCCCAGTGTAAAGAAATGGTTTAAG
CAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTT
CACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCT
GTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTG
TGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTG
CTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGG
GAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGG
TGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACT
CCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTG

>In-frame_LIMCH1_ENST00000512946_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_1117nt
GGCGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTC
AGCCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCG
CGAGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCA
TCGCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCT
CAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAA
CCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAAT
GTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGC
ATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAA
TCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTT
CCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAAT
ATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCAC
CAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTAAAATGATATT

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_1245nt
CGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAG
CCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCG
AGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATC
GCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGGGTAGTGATTTGATCTCCAGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAA
AGAGAAGGCTACCCCCATGATAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCTCTACTGCCGCCCCAGTGTAAAGAAATGGTTTAAGCA
GCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCA
CTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGT
CCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTG
TAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCT
TTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGA
ACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTG
TTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCC
AACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCT

>In-frame_LIMCH1_ENST00000313860_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_1115nt
CGACGGCGGCGGCCGTCCTCATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAG
CCCCTGCAGCCCGAGCCGCCCCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCG
AGCGGCCCCACAGAGGACCAGGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATC
GCGGCCGAGGCAGGCCTTTCCGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCA
GAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACC
AAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGT
ACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCAT
TTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATC
CATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCC
TTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATAT
AGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCA
AAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTAAAATGATATTCT

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_1225nt
ATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCC
CCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCA
GGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTC
CGAGGAGGAGACCCAGGGTAGTGATTTGATCTCCAGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGA
TAGTCTGCCGTGCTTGGCTTTCGATTACTTTTCTCTACTGCCGCCCCAGTGTAAAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGC
GCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTG
TTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGT
TGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGG
AAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGT
AGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTT
ACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCAT
AAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCA
TCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTT

>In-frame_LIMCH1_ENST00000512632_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_1095nt
ATCCCGGCGCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCC
CCCCGAGCCCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCA
GGTGGAAATCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTC
CGAGGAGGAGACCCAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGA
CTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAG
CATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAAT
AACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGA
CAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTC
TGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAA
TGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAG
AAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATA
TTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTAAAATGATATTCTAAATAAAACCTTAACTTTTT

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000554144_chr4_57522178_-_1217nt
GCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGC
CCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAA
TCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGG
AGACCCAGGGTAGTGATTTGATCTCCAGGAGCAAAATATGGCACCCAGAAAGTAGCCCCCAAAGAGAAGGCTACCCCCATGATAGTCTGC
CGTGCTTGGCTTTCGATTACTTTTCTCTACTGCCGCCCCAGTGTAAAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAA
GGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAGATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTC
CTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGTTGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTT
TTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAGGAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGG
TGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGTGTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTT
GCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAAAGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCT
AAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTTGAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACT
TCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGTTGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAA
AAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATGCATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTA

>In-frame_LIMCH1_ENST00000512820_chr4_41362953_+_HOPX_ENST00000420433_chr4_57522178_-_1087nt
GCTTGAGAGGACGCGGGGCTGCGCAAATGGCTTGTCCCGCTCTCGGTCTGGAAGCTCTTCAGCCCCTGCAGCCCGAGCCGCCCCCCGAGC
CCGCCTTCTCCGAGGCGCAGAAGTGGATTGAGCGCGCAGGGACCATGTCGGCGGAGACCGCGAGCGGCCCCACAGAGGACCAGGTGGAAA
TCCTGGAGTACAACTTCAACAAGGTCGACAAGCACCCGGATTCCACCACGCTGTGCCTCATCGCGGCCGAGGCAGGCCTTTCCGAGGAGG
AGACCCAGAAATGGTTTAAGCAGCGCCTGGCAAAGTGGCGGCGCTCAGAAGGCCTGCCCTCAGAGTGCAGATCCGTCACAGACTAAGGAG
ATGGCAGGCATTGACAGCTTCACTCCATGAAGGCCATCTCTGTTTCTCTCCTCCGCTTAACCAAGCTGTTGTGGTTTTTCAGCATAGTGT
TGTATGTTCCATTGCTAGCTGTCCTGCTGTTTAACACAGTGTTGTATTTTTTTTCTAAATGTACATAATTAGAAAAGAAAATAACAATAG
GAAGCTATGTGTATCTTCTGTGTAAAGCAGTGGCTTCACTGGAAAAATGGTGTGGCTAGCATTTCCCTTTGAGTCATGATGACAGATGGT
GTGAAAACCATCTAAGTTTGCTTTTGACCATCACCTCCCAGTAGCAATTTGCTTTCATAATCCATTTAGCAATCCAGGCCTCTGTTGAAA
AGATAATATGAGGGAGAAGGGAACACATTTCCTTCTGAACTTACTTCCCTAAGTCACTTTCCTTATGTATCATCTAATACAATGATGGTT
GAGTGAAAATACAGAAGGGGTGTTTGAGTATTCAGATTTCATAAAACACTTCCTTGGAATATAGCTGCATTAACTTGGAAAGAAGCCTGT
TGGGCCAGAAGACAGAAACTCCAACTGGCAAAAAAGCAAGCATCTAAGAAAAAAAACCACCAAAGTTCTTGAATTTACTATATTTAAATG
CATTGGTTAAGTTTATTTTGCTAAATAAAGTGAACTGCTTTTTGTCTCTAAAATGATATTCTAAATAAAACCTTAACTTTTTGTTGAAGA


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FusionGenePPI for LIMCH1_HOPX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
LIMCH1ELAVL1, SH3KBP1, APP, HUWE1, CUTC, DIABLO, GABPA, KPNA1, NPM1, TRMT61A, RPA3, RPA2, RPA1, OTUD6B, KLHL15, RFC2, YES1, NAGK, GNB4, UNK, NTRK1, CEP120, ODF2, XPO1, CAPZA2, CDK2, MYH9, PPP1CB, IQGAP1, ANLN, MYO19, MYO18A, CDH1, TRIM25HOPXHDAC2, HOXB9, TLX3, ZSCAN1, HSP90AA1, HSPA4, EPC1, TCF12, S100A2, ASUN


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LIMCH1_HOPX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LIMCH1_HOPX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLIMCH1C0236969Substance-Related Disorders1CTD_human
HgeneLIMCH1C0345967Malignant mesothelioma1CTD_human
TgeneHOPXC0023893Liver Cirrhosis, Experimental1CTD_human