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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 1972

FusionGeneSummary for ANTXR2_OR7E94P

check button Fusion gene summary
Fusion gene informationFusion gene name: ANTXR2_OR7E94P
Fusion gene ID: 1972
HgeneTgene
Gene symbol

ANTXR2

OR7E94P

Gene ID

118429

79273

Gene nameANTXR cell adhesion molecule 2olfactory receptor family 7 subfamily E member 94 pseudogene
SynonymsCMG-2|CMG2|HFS|ISH|JHF-
Cytomap

4q21.21

4q21.21

Type of geneprotein-codingpseudo
Descriptionanthrax toxin receptor 2capillary morphogenesis gene 2 proteincapillary morphogenesis protein 2-
Modification date2018052320180329
UniProtAcc

P58335

Ensembl transtripts involved in fusion geneENST00000403729, ENST00000482406, 
ENST00000404191, ENST00000346652, 
ENST00000307333, ENST00000295465, 
ENST00000601375, 
Fusion gene scores* DoF score5 X 6 X 3=901 X 1 X 1=1
# samples 81
** MAII scorelog2(8/90*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: ANTXR2 [Title/Abstract] AND OR7E94P [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDCOADTCGA-D5-6932-01AANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000403729ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
intron-3CDSENST00000482406ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
Frame-shiftENST00000404191ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
intron-3CDSENST00000346652ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
In-frameENST00000307333ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-
In-frameENST00000295465ENST00000601375ANTXR2chr4

80952777

-OR7E94Pchr4

80509244

-

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FusionProtFeatures for ANTXR2_OR7E94P


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANTXR2

P58335

OR7E94P

Necessary for cellular interactions with laminin and theextracellular matrix. {ECO:0000269|PubMed:11683410,ECO:0000269|PubMed:12973667}. Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-101144_213288323DomainVWFA
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-101644_213288490DomainVWFA
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-101744_213288489DomainVWFA

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-1011352_360288323Compositional biasNote=Poly-Pro
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-1011362_366288323Compositional biasNote=Poly-Glu
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-1016352_360288490Compositional biasNote=Poly-Pro
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-1016362_366288490Compositional biasNote=Poly-Glu
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-112352_360-47387Compositional biasNote=Poly-Pro
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-112362_366-47387Compositional biasNote=Poly-Glu
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-1017352_360288489Compositional biasNote=Poly-Pro
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-1017362_366288489Compositional biasNote=Poly-Glu
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-11244_213-47387DomainVWFA
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-1011342_489288323Topological domainCytoplasmic
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-101134_318288323Topological domainExtracellular
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-1016342_489288490Topological domainCytoplasmic
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-101634_318288490Topological domainExtracellular
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-112342_489-47387Topological domainCytoplasmic
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-11234_318-47387Topological domainExtracellular
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-1017342_489288489Topological domainCytoplasmic
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-101734_318288489Topological domainExtracellular
HgeneANTXR2chr4:80952777chr4:80509244ENST00000295465-1011319_341288323TransmembraneHelical
HgeneANTXR2chr4:80952777chr4:80509244ENST00000307333-1016319_341288490TransmembraneHelical
HgeneANTXR2chr4:80952777chr4:80509244ENST00000346652-112319_341-47387TransmembraneHelical
HgeneANTXR2chr4:80952777chr4:80509244ENST00000403729-1017319_341288489TransmembraneHelical


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FusionGeneSequence for ANTXR2_OR7E94P


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ANTXR2_ENST00000403729_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_288aa
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT
IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD
FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV

>In-frame_ANTXR2_ENST00000307333_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_288aa
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT
IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD
FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV

>In-frame_ANTXR2_ENST00000295465_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_288aa
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT
IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD
FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ANTXR2_ENST00000403729_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_866nt
ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG
CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT
GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT
ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC
CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG
TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT
TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT
AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT
GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA

>In-frame_ANTXR2_ENST00000307333_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_866nt
ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG
CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT
GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT
ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC
CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG
TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT
TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT
AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT
GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA

>In-frame_ANTXR2_ENST00000295465_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_866nt
ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG
CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT
GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT
ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC
CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG
TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT
TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT
AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT
GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ANTXR2_ENST00000403729_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_2182nt
TTTCGGAGTGCGGAGGGAGTTGGGGCCGCCGGAGGAGAAGAGTCTCCACTCCTAGTTTGTTCTGCCGTCGCCGCGTCCCAGGGACCCCTT
GTCCCGAAGCGCACGGCAGCGGGGGGGACTTCAGCCCTCCAGGCGGGGTGGGTTCCAGGTCCGGGTCCGAGGCGGGCGCTGGAGGCTCGG
CCCCAGGCCGGAGAGGAACTCCTTTCGCGAGCTGTCGCCGTGGGCCCGCATTGTCTGCAGGAACTCTCCGGAATCGGGAGGGGGAGGACT
GGATCGCGCTTCCACTGGGATTCGTCAAGAGTTCCGGCGGCAGCTGCGGCGGTGGCGGAGACTCCCTTTGTCCTCTCAGGACCTCCCTCT
CTCCCTCCCTGTCAGCTGGTGGGTCCCGCTGCCGCAGGCGCCGGCGTCTCAGCTGCTCGCCGCCCCCCACCCCAGAGTGCGTGCCGGGTG
ACTCCCGCCACCTTTGCGACCCTCCTGAGCTTAGGGGACTGCGAGCGGGAGGGAGTCTCAGGCCCCCGGCCGCAGGATGGTGGCGGAGCG
GTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGA
GCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATTGAAATTTATAATTT
CGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATT
AACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATCCATGAAGGACTAAA
GCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGT
GCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGATTTTGAACAAGCACA
GCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGC
TCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGTGGAAGAGGATTCAT
GCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAA
TTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAGGTGTCCAAGTCACACAGAACCACAGAATCTCACAGGTGTCTCAGAAT
TCCTTCTCCTGGGACTCTCAGAGGATCCAGAACTGCAGCCTGTCCTCGCTTGGCTGTCCTTGTCCATTTACCTGGTCACAGTGCTGGGGA
ACCTGCTCATCATCCTGGCTGTCAGCTCTGACTCCCACCTCCACACCCCCATATACTTCTTCCTCTTCAACCTGTCCTTGGCTGACATTG
GTTTCACCTCGGCCATGGTTCCCAAGATGATTGTGGACATGCAATCGCATAGCAGAGTCATCTCTTATGCGGGCTGCCTGACATAGATGT
CTTTCTTTGTCCTTTTTTTTTCAATTATTATTATACTTTAAGTTCTAGGGTACATGTGCACAACGTGCAGGTTTGTTATATATGTATACA
TGTGCCATGTTGGTGTGCTGCACCCATTAACTCGTCATTTACATTAGGTATATCTTCTAATGTTATCCCTCCCTCCTCCCCCCAGCCCAC
GACAGGCCCCAGTGTGTGATGTTCCCCATCCTGTGTCCAAGTGTTCTCATTGTTCAATTCCAACCTGTAAGTGAGAACATGCGGTGTTTG
GTTTTCTGTCCTTGCAATAGCTTGCTGAGAATGATGGTTTCCAGCTTCATCCATGTCCCTACAAAGTACATGAACTCATCCCTTTTTATG
GCTGCATAGTATTCCATGGAAGACATGTCTAATGTTTAAAGGTTGTAAATAAGGCAAATAACTCATAAATAAAACATGTCCTGTTCTCTT

>In-frame_ANTXR2_ENST00000307333_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_1659nt
AGGATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGG
CTGCTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGG
ATTGAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCA
ACTATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATAT
ATCCATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGC
AAGTTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTT
GATTTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATA
ATTAATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTA
AGTGGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCA
GTAAGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAGGTGTCCAAGTCACACAGAACCACAGAATCT
CACAGGTGTCTCAGAATTCCTTCTCCTGGGACTCTCAGAGGATCCAGAACTGCAGCCTGTCCTCGCTTGGCTGTCCTTGTCCATTTACCT
GGTCACAGTGCTGGGGAACCTGCTCATCATCCTGGCTGTCAGCTCTGACTCCCACCTCCACACCCCCATATACTTCTTCCTCTTCAACCT
GTCCTTGGCTGACATTGGTTTCACCTCGGCCATGGTTCCCAAGATGATTGTGGACATGCAATCGCATAGCAGAGTCATCTCTTATGCGGG
CTGCCTGACATAGATGTCTTTCTTTGTCCTTTTTTTTTCAATTATTATTATACTTTAAGTTCTAGGGTACATGTGCACAACGTGCAGGTT
TGTTATATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCGTCATTTACATTAGGTATATCTTCTAATGTTATCCCTCCC
TCCTCCCCCCAGCCCACGACAGGCCCCAGTGTGTGATGTTCCCCATCCTGTGTCCAAGTGTTCTCATTGTTCAATTCCAACCTGTAAGTG
AGAACATGCGGTGTTTGGTTTTCTGTCCTTGCAATAGCTTGCTGAGAATGATGGTTTCCAGCTTCATCCATGTCCCTACAAAGTACATGA
ACTCATCCCTTTTTATGGCTGCATAGTATTCCATGGAAGACATGTCTAATGTTTAAAGGTTGTAAATAAGGCAAATAACTCATAAATAAA

>In-frame_ANTXR2_ENST00000295465_chr4_80952777_-_OR7E94P_ENST00000601375_chr4_80509244_-_2419nt
AGTCATCTTCAACTCGGCAGGAACCCACAAGTGTGCATGTGTGGCTCGGAGGCTTCAGCTGGGGCCCCGCCCTCGTCCCCAGGCGCACAC
TGACACACGCAGCCCAGACCCGGCCCGAGCGGGCTCCTGCCCTCGGCGTGGCTTCTCTCCAGCCGGGAGTCCCAGGGCCAGCTAGCCTCC
TCCCCTAAAGGGGACGGCCTGTCAGCGCAGTGCCAGAGTCCAGCACCGGGAGGAAAGTTTCGGAGTGCGGAGGGAGTTGGGGCCGCCGGA
GGAGAAGAGTCTCCACTCCTAGTTTGTTCTGCCGTCGCCGCGTCCCAGGGACCCCTTGTCCCGAAGCGCACGGCAGCGGGGGGGACTTCA
GCCCTCCAGGCGGGGTGGGTTCCAGGTCCGGGTCCGAGGCGGGCGCTGGAGGCTCGGCCCCAGGCCGGAGAGGAACTCCTTTCGCGAGCT
GTCGCCGTGGGCCCGCATTGTCTGCAGGAACTCTCCGGAATCGGGAGGGGGAGGACTGGATCGCGCTTCCACTGGGATTCGTCAAGAGTT
CCGGCGGCAGCTGCGGCGGTGGCGGAGACTCCCTTTGTCCTCTCAGGACCTCCCTCTCTCCCTCCCTGTCAGCTGGTGGGTCCCGCTGCC
GCAGGCGCCGGCGTCTCAGCTGCTCGCCGCCCCCCACCCCAGAGTGCGTGCCGGGTGACTCCCGCCACCTTTGCGACCCTCCTGAGCTTA
GGGGACTGCGAGCGGGAGGGAGTCTCAGGCCCCCGGCCGCAGGATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTT
CCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTA
CTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATTGAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCC
TGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTT
GGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATCCATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGG
CTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATC
CAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGATTTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGT
TTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCC
CTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGTGGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCAC
TTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAA
AGCTGGAGAGGTGTCCAAGTCACACAGAACCACAGAATCTCACAGGTGTCTCAGAATTCCTTCTCCTGGGACTCTCAGAGGATCCAGAAC
TGCAGCCTGTCCTCGCTTGGCTGTCCTTGTCCATTTACCTGGTCACAGTGCTGGGGAACCTGCTCATCATCCTGGCTGTCAGCTCTGACT
CCCACCTCCACACCCCCATATACTTCTTCCTCTTCAACCTGTCCTTGGCTGACATTGGTTTCACCTCGGCCATGGTTCCCAAGATGATTG
TGGACATGCAATCGCATAGCAGAGTCATCTCTTATGCGGGCTGCCTGACATAGATGTCTTTCTTTGTCCTTTTTTTTTCAATTATTATTA
TACTTTAAGTTCTAGGGTACATGTGCACAACGTGCAGGTTTGTTATATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATTAACTC
GTCATTTACATTAGGTATATCTTCTAATGTTATCCCTCCCTCCTCCCCCCAGCCCACGACAGGCCCCAGTGTGTGATGTTCCCCATCCTG
TGTCCAAGTGTTCTCATTGTTCAATTCCAACCTGTAAGTGAGAACATGCGGTGTTTGGTTTTCTGTCCTTGCAATAGCTTGCTGAGAATG
ATGGTTTCCAGCTTCATCCATGTCCCTACAAAGTACATGAACTCATCCCTTTTTATGGCTGCATAGTATTCCATGGAAGACATGTCTAAT


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FusionGenePPI for ANTXR2_OR7E94P


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ANTXR2SMAD2, COL4A5, LAMB1, LAMC1, LGR4, TCEB3, HS1BP3, IKBIP, ANKRD13DOR7E94P


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ANTXR2_OR7E94P


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ANTXR2_OR7E94P


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneANTXR2C0009917Contracture2CTD_human
HgeneANTXR2C0016045fibroma2CTD_human
HgeneANTXR2C0017567Gingival Hypertrophy2CTD_human
HgeneANTXR2C0038013Ankylosing spondylitis2CTD_human
HgeneANTXR2C2745948Hyalinosis, Systemic2CTD_human;ORPHANET;UNIPROT
HgeneANTXR2C0029456Osteoporosis1CTD_human
HgeneANTXR2C0221204Lytic lesion1CTD_human