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Fusion gene ID: 1970 |
FusionGeneSummary for ANTXR2_CHMP1A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANTXR2_CHMP1A | Fusion gene ID: 1970 | Hgene | Tgene | Gene symbol | ANTXR2 | CHMP1A | Gene ID | 118429 | 5119 |
| Gene name | ANTXR cell adhesion molecule 2 | charged multivesicular body protein 1A | |
| Synonyms | CMG-2|CMG2|HFS|ISH|JHF | CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A | |
| Cytomap | 4q21.21 | 16q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | anthrax toxin receptor 2capillary morphogenesis gene 2 proteincapillary morphogenesis protein 2 | charged multivesicular body protein 1acharged multivesicular body protein 1/chromatin modifying protein 1chromatin modifying protein 1Aprocollagen (type III) N-endopeptidaseprotease, metallo, 1, 33kDvacuolar protein sorting-associated protein 46-1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P58335 | Q9HD42 | |
| Ensembl transtripts involved in fusion gene | ENST00000403729, ENST00000482406, ENST00000404191, ENST00000346652, ENST00000307333, ENST00000295465, | ENST00000397901, ENST00000253475, ENST00000535997, ENST00000550102, ENST00000547614, | |
| Fusion gene scores | * DoF score | 5 X 6 X 3=90 | 15 X 8 X 9=1080 |
| # samples | 8 | 20 | |
| ** MAII score | log2(8/90*10)=-0.169925001442312 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(20/1080*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANTXR2 [Title/Abstract] AND CHMP1A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CHMP1A | GO:0007076 | mitotic chromosome condensation | 11559747 |
| Tgene | CHMP1A | GO:0016192 | vesicle-mediated transport | 11559748 |
| Tgene | CHMP1A | GO:0016458 | gene silencing | 11559747 |
| Tgene | CHMP1A | GO:0045892 | negative regulation of transcription, DNA-templated | 11559747 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-EJ-5506-01A | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| TCGA | LD | PRAD | TCGA-EJ-7125-01A | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000403729 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| Frame-shift | ENST00000403729 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| In-frame | ENST00000403729 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| In-frame | ENST00000403729 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| 5CDS-5UTR | ENST00000403729 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000482406 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000482406 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000482406 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000482406 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-5UTR | ENST00000482406 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| Frame-shift | ENST00000404191 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| In-frame | ENST00000404191 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| Frame-shift | ENST00000404191 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| Frame-shift | ENST00000404191 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| 5CDS-5UTR | ENST00000404191 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000346652 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000346652 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000346652 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000346652 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-5UTR | ENST00000346652 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000307333 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000307333 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000307333 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000307333 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-5UTR | ENST00000307333 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000295465 | ENST00000397901 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000295465 | ENST00000253475 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000295465 | ENST00000535997 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-3CDS | ENST00000295465 | ENST00000550102 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
| intron-5UTR | ENST00000295465 | ENST00000547614 | ANTXR2 | chr4 | 80898775 | - | CHMP1A | chr16 | 89713739 | - |
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FusionProtFeatures for ANTXR2_CHMP1A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANTXR2 | CHMP1A |
| Necessary for cellular interactions with laminin and theextracellular matrix. {ECO:0000269|PubMed:11683410,ECO:0000269|PubMed:12973667}. | Probable peripherally associated component of theendosomal sorting required for transport complex III (ESCRT-III)which is involved in multivesicular bodies (MVBs) formation andsorting of endosomal cargo proteins into MVBs. MVBs containintraluminal vesicles (ILVs) that are generated by invaginationand scission from the limiting membrane of the endosome and mostlyare delivered to lysosomes enabling degradation of membraneproteins, such as stimulated growth factor receptors, lysosomalenzymes and lipids. The MVB pathway appears to require thesequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions intopologically equivalent membrane fission events, such as theterminal stages of cytokinesis and the budding of envelopedviruses (HIV-1 and other lentiviruses). ESCRT-III proteins arebelieved to mediate the necessary vesicle extrusion and/ormembrane fission activities, possibly in conjunction with the AAAATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4Aand/or VPS4B to the midbody of dividing cells. May also beinvolved in chromosome condensation. Targets the Polycomb group(PcG) protein BMI1/PCGF4 to regions of condensed chromatin. Mayplay a role in stable cell cycle progression and in PcG genesilencing. {ECO:0000269|PubMed:11559747,ECO:0000269|PubMed:11559748, ECO:0000269|PubMed:19129479,ECO:0000269|PubMed:23045692}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 352_360 | 476 | 489 | Compositional bias | Note=Poly-Pro |
| Hgene | ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 362_366 | 476 | 489 | Compositional bias | Note=Poly-Glu |
| Hgene | ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 44_213 | 476 | 489 | Domain | VWFA |
| Hgene | ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 34_318 | 476 | 489 | Topological domain | Extracellular |
| Hgene | ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 319_341 | 476 | 489 | Transmembrane | Helical |
| Tgene | >CHMP1A | chr4:80898775 | chr16:89713739 | ENST00000397901 | - | 3 | 7 | 102_124 | 84 | 197 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CHMP1A | chr4:80898775 | chr16:89713739 | ENST00000397901 | - | 3 | 7 | 185_195 | 84 | 197 | Motif | Note=MIT-interacting motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 352_360 | -255 | 323 | Compositional bias | Note=Poly-Pro |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 362_366 | -255 | 323 | Compositional bias | Note=Poly-Glu |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 352_360 | -1 | 490 | Compositional bias | Note=Poly-Pro |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 362_366 | -1 | 490 | Compositional bias | Note=Poly-Glu |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 352_360 | -47 | 387 | Compositional bias | Note=Poly-Pro |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 362_366 | -47 | 387 | Compositional bias | Note=Poly-Glu |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 44_213 | -255 | 323 | Domain | VWFA |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 44_213 | -1 | 490 | Domain | VWFA |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 44_213 | -47 | 387 | Domain | VWFA |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 342_489 | -255 | 323 | Topological domain | Cytoplasmic |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 34_318 | -255 | 323 | Topological domain | Extracellular |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 342_489 | -1 | 490 | Topological domain | Cytoplasmic |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 34_318 | -1 | 490 | Topological domain | Extracellular |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 342_489 | -47 | 387 | Topological domain | Cytoplasmic |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 34_318 | -47 | 387 | Topological domain | Extracellular |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000403729 | - | 16 | 17 | 342_489 | 476 | 489 | Topological domain | Cytoplasmic |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000295465 | - | 1 | 11 | 319_341 | -255 | 323 | Transmembrane | Helical |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000307333 | - | 1 | 16 | 319_341 | -1 | 490 | Transmembrane | Helical |
| Hgene | >ANTXR2 | chr4:80898775 | chr16:89713739 | ENST00000346652 | - | 1 | 12 | 319_341 | -47 | 387 | Transmembrane | Helical |
| Tgene | CHMP1A | chr4:80898775 | chr16:89713739 | ENST00000397901 | - | 3 | 7 | 5_47 | 84 | 197 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for ANTXR2_CHMP1A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000397901_chr16_89713739_-_589aa MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV SVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKG RLDALWALLRRQYDRVSLMRPQEGDEVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDS >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000535997_chr16_89713739_-_589aa MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV SVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKG RLDALWALLRRQYDRVSLMRPQEGDEVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDS >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000550102_chr16_89713739_-_589aa MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQAT IILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPV SVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKG RLDALWALLRRQYDRVSLMRPQEGDEVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDS >In-frame_ANTXR2_ENST00000404191_chr4_80898775_-_CHMP1A_ENST00000253475_chr16_89713739_-_163aa VTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000397901_chr16_89713739_-_1767nt ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA AGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGA AAATCTGTCATTTCAGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTA CTCCTGGGGATCGGTTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCA AAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAA AGAATGGAGGTTCGTTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAA GAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGT CGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAAT ATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAG GTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGC CTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGC >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000535997_chr16_89713739_-_1767nt ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA AGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGA AAATCTGTCATTTCAGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTA CTCCTGGGGATCGGTTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCA AAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAA AGAATGGAGGTTCGTTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAA GAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGT CGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAAT ATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAG GTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGC CTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGC >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000550102_chr16_89713739_-_1767nt ATGGTGGCGGAGCGGTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTG CTGCGCGCCCAGGAGCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATT GAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACT ATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATC CATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAG TTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGAT TTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATT AATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGT GGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTA AGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGA AAATCTGTCATTTCAGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTA CTCCTGGGGATCGGTTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCA AAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAA AGAATGGAGGTTCGTTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAA GAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGT CGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAAT ATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAG GTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGC CTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGC >In-frame_ANTXR2_ENST00000404191_chr4_80898775_-_CHMP1A_ENST00000253475_chr16_89713739_-_491nt GTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGG TTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAG CAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCC GTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCAC CGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000397901_chr16_89713739_-_3928nt TTTCGGAGTGCGGAGGGAGTTGGGGCCGCCGGAGGAGAAGAGTCTCCACTCCTAGTTTGTTCTGCCGTCGCCGCGTCCCAGGGACCCCTT GTCCCGAAGCGCACGGCAGCGGGGGGGACTTCAGCCCTCCAGGCGGGGTGGGTTCCAGGTCCGGGTCCGAGGCGGGCGCTGGAGGCTCGG CCCCAGGCCGGAGAGGAACTCCTTTCGCGAGCTGTCGCCGTGGGCCCGCATTGTCTGCAGGAACTCTCCGGAATCGGGAGGGGGAGGACT GGATCGCGCTTCCACTGGGATTCGTCAAGAGTTCCGGCGGCAGCTGCGGCGGTGGCGGAGACTCCCTTTGTCCTCTCAGGACCTCCCTCT CTCCCTCCCTGTCAGCTGGTGGGTCCCGCTGCCGCAGGCGCCGGCGTCTCAGCTGCTCGCCGCCCCCCACCCCAGAGTGCGTGCCGGGTG ACTCCCGCCACCTTTGCGACCCTCCTGAGCTTAGGGGACTGCGAGCGGGAGGGAGTCTCAGGCCCCCGGCCGCAGGATGGTGGCGGAGCG GTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGA GCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATTGAAATTTATAATTT CGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATT AACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATCCATGAAGGACTAAA GCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGT GCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGATTTTGAACAAGCACA GCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGC TCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGTGGAAGAGGATTCAT GCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAA TTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGAAAATCTGTCATTTC AGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTACTCCTGGGGATCGG TTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCAAAAGAGGAGGAAGA AGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCG TTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAAGAAACAGAGGAACC CATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGTCGTCTTGATGCTCT CTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAATATGGCCCAGGTGAC CAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGA CGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGAT CGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCA GGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAA GGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGG CCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGA TTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCA GCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGG GCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTG TCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGC CTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCA CCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCT GTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCC CTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCT TGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTG TGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTC CTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGA GTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGT GGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCT AGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAA CAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCC >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000535997_chr16_89713739_-_3896nt TTTCGGAGTGCGGAGGGAGTTGGGGCCGCCGGAGGAGAAGAGTCTCCACTCCTAGTTTGTTCTGCCGTCGCCGCGTCCCAGGGACCCCTT GTCCCGAAGCGCACGGCAGCGGGGGGGACTTCAGCCCTCCAGGCGGGGTGGGTTCCAGGTCCGGGTCCGAGGCGGGCGCTGGAGGCTCGG CCCCAGGCCGGAGAGGAACTCCTTTCGCGAGCTGTCGCCGTGGGCCCGCATTGTCTGCAGGAACTCTCCGGAATCGGGAGGGGGAGGACT GGATCGCGCTTCCACTGGGATTCGTCAAGAGTTCCGGCGGCAGCTGCGGCGGTGGCGGAGACTCCCTTTGTCCTCTCAGGACCTCCCTCT CTCCCTCCCTGTCAGCTGGTGGGTCCCGCTGCCGCAGGCGCCGGCGTCTCAGCTGCTCGCCGCCCCCCACCCCAGAGTGCGTGCCGGGTG ACTCCCGCCACCTTTGCGACCCTCCTGAGCTTAGGGGACTGCGAGCGGGAGGGAGTCTCAGGCCCCCGGCCGCAGGATGGTGGCGGAGCG GTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGA GCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATTGAAATTTATAATTT CGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATT AACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATCCATGAAGGACTAAA GCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGT GCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGATTTTGAACAAGCACA GCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGC TCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGTGGAAGAGGATTCAT GCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAA TTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGAAAATCTGTCATTTC AGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTACTCCTGGGGATCGG TTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCAAAAGAGGAGGAAGA AGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCG TTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAAGAAACAGAGGAACC CATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGTCGTCTTGATGCTCT CTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAATATGGCCCAGGTGAC CAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGA CGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGAT CGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCA GGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAA GGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGG CCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGA TTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCA GCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGG GCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTG TCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGC CTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCA CCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCT GTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCC CTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCT TGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTG TGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTC CTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGA GTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGT GGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCT AGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAA CAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCC >In-frame_ANTXR2_ENST00000403729_chr4_80898775_-_CHMP1A_ENST00000550102_chr16_89713739_-_2470nt TTTCGGAGTGCGGAGGGAGTTGGGGCCGCCGGAGGAGAAGAGTCTCCACTCCTAGTTTGTTCTGCCGTCGCCGCGTCCCAGGGACCCCTT GTCCCGAAGCGCACGGCAGCGGGGGGGACTTCAGCCCTCCAGGCGGGGTGGGTTCCAGGTCCGGGTCCGAGGCGGGCGCTGGAGGCTCGG CCCCAGGCCGGAGAGGAACTCCTTTCGCGAGCTGTCGCCGTGGGCCCGCATTGTCTGCAGGAACTCTCCGGAATCGGGAGGGGGAGGACT GGATCGCGCTTCCACTGGGATTCGTCAAGAGTTCCGGCGGCAGCTGCGGCGGTGGCGGAGACTCCCTTTGTCCTCTCAGGACCTCCCTCT CTCCCTCCCTGTCAGCTGGTGGGTCCCGCTGCCGCAGGCGCCGGCGTCTCAGCTGCTCGCCGCCCCCCACCCCAGAGTGCGTGCCGGGTG ACTCCCGCCACCTTTGCGACCCTCCTGAGCTTAGGGGACTGCGAGCGGGAGGGAGTCTCAGGCCCCCGGCCGCAGGATGGTGGCGGAGCG GTCCCCGGCCCGCAGCCCCGGGAGCTGGCTGTTCCCCGGGCTGTGGCTGTTGGTGCTCAGCGGTCCCGGGGGGCTGCTGCGCGCCCAGGA GCAGCCCTCCTGCAGAAGAGCCTTTGATCTCTACTTCGTCCTGGACAAGTCTGGGAGTGTGGCAAATAACTGGATTGAAATTTATAATTT CGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTTTTCTTCTCAAGCAACTATTATTTTGCCATT AACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGTAGGAGAGACATATATCCATGAAGGACTAAA GCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGCTCTGACAGATGGCAAGTTGGACGGTCTGGT GCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTGTGTTGGTGTCCTTGATTTTGAACAAGCACA GCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGCTCTTAAAGGAATAATTAATTCTATACTAGC TCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATTTCAGATTGTCTTAAGTGGAAGAGGATTCAT GCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAACGAGTGTAAAACCAGTAAGTGTACAGCTTAA TTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGTGAGCTTTAATGGAGGAAAATCTGTCATTTC AGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTATTTTGGTGTTACTGCTACTCCTGGGGATCGG TTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCAAAAGAGGAGGAAGA AGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCG TTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAAGAAACAGAGGAACC CATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGTCGTCTTGATGCTCT CTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGTGACCAAGAATATGGCCCAGGTGAC CAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGA CGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGAT CGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCA GGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAA GGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGG >In-frame_ANTXR2_ENST00000404191_chr4_80898775_-_CHMP1A_ENST00000253475_chr16_89713739_-_3321nt AGTCTTGGGTTTGTGAACCACGCATGGGGGCTGTTTTAGCACAGCTGCTAAAATAGGCCAGGCCTGCAGGACATACGGGTCTGGGAGTGT GGCAAATAACTGGATTGAAATTTATAATTTCGTACAGCAACTTGCGGAGAGATTTGTGAGCCCTGAAATGAGATTATCTTTCATTGTGTT TTCTTCTCAAGCAACTATTATTTTGCCATTAACTGGAGACAGAGGCAAAATCAGTAAAGGCTTGGAGGATTTAAAACGTGTTAGTCCAGT AGGAGAGACATATATCCATGAAGGACTAAAGCTAGCGAATGAACAAATTCAGAAAGCAGGAGGCTTGAAAACCTCCAGTATCATAATTGC TCTGACAGATGGCAAGTTGGACGGTCTGGTGCCATCATATGCAGAGAAAGAGGCAAAGATATCCAGGTCACTTGGGGCTAGTGTTTATTG TGTTGGTGTCCTTGATTTTGAACAAGCACAGCTTGAAAGAATTGCTGATTCCAAGGAGCAAGTTTTCCCTGTCAAAGGTGGATTTCAGGC TCTTAAAGGAATAATTAATTCTATACTAGCTCAGTCATGTACTGAAATCCTAGAATTGCAGCCCTCAAGTGTCTGTGTGGGGGAGGAATT TCAGATTGTCTTAAGTGGAAGAGGATTCATGCTGGGCAGTCGGAATGGCAGTGTTCTCTGCACTTACACTGTAAATGAAACATATACAAC GAGTGTAAAACCAGTAAGTGTACAGCTTAATTCTATGCTTTGTCCTGCACCTATCCTGAATAAAGCTGGAGAAACTCTTGATGTTTCAGT GAGCTTTAATGGAGGAAAATCTGTCATTTCAGGATCATTAATTGTCACAGCCACAGAATGTTCTAACGGGATCGCAGCCATCATTGTTAT TTTGGTGTTACTGCTACTCCTGGGGATCGGTTTGATGTGGTGGTTTTGGCCCCTTTGCTGCAAAGTGGTTATTAAGGATCCTCCACCACC ACCCGCCCCTGCACCAAAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGG GGTTGGAGGAATTAAAAGAATGGAGGTTCGTTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGT GGTGAAGATTCCTGAAGAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTA CACCCCAATTAAGGGTCGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGA TGAGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGA CAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCA GGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTC TGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGT GCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCG GCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGG TGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCA GCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACT CCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTG CTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGC CGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACC GTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGC TGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCT GGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTT CCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGT TGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCT TTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAG AAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTG CAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTT TCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTG AGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTC |
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FusionGenePPI for ANTXR2_CHMP1A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ANTXR2 | SMAD2, COL4A5, LAMB1, LAMC1, LGR4, TCEB3, HS1BP3, IKBIP, ANKRD13D | CHMP1A | KIAA1715, VPS4A, STAMBP, USP8, NR1I2, VPS4B, CHMP1A, CHMP1B, UBE2I, ATP6V1B1, FBXL18, OAS3, MOV10, NXF1, ZDHHC17, MEOX1, IST1, VSX2, LHX4, ZNF524, CLTC, RAB5C, RAB7A, TFG, GOLT1B, CHMP4B, MCM2, NF2, CHMP5, SIX2, BROX, HMGN2, GPX7, MECP2, HEY2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ANTXR2_CHMP1A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANTXR2_CHMP1A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ANTXR2 | C0009917 | Contracture | 2 | CTD_human |
| Hgene | ANTXR2 | C0016045 | fibroma | 2 | CTD_human |
| Hgene | ANTXR2 | C0017567 | Gingival Hypertrophy | 2 | CTD_human |
| Hgene | ANTXR2 | C0038013 | Ankylosing spondylitis | 2 | CTD_human |
| Hgene | ANTXR2 | C2745948 | Hyalinosis, Systemic | 2 | CTD_human;ORPHANET;UNIPROT |
| Hgene | ANTXR2 | C0029456 | Osteoporosis | 1 | CTD_human |
| Hgene | ANTXR2 | C0221204 | Lytic lesion | 1 | CTD_human |
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