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Fusion gene ID: 19476 |
FusionGeneSummary for LARP4_HPD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LARP4_HPD | Fusion gene ID: 19476 | Hgene | Tgene | Gene symbol | LARP4 | HPD | Gene ID | 113251 | 3242 |
| Gene name | La ribonucleoprotein domain family member 4 | 4-hydroxyphenylpyruvate dioxygenase | |
| Synonyms | PP13296 | 4-HPPD|4HPPD|GLOD3|HPPDASE|PPD | |
| Cytomap | 12q13.12 | 12q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | la-related protein 4c-Mpl binding protein | 4-hydroxyphenylpyruvate dioxygenase4-hydroxyphenylpyruvic acid oxidaseglyoxalase domain containing 3 | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | Q71RC2 | P32754 | |
| Ensembl transtripts involved in fusion gene | ENST00000293618, ENST00000429001, ENST00000398473, ENST00000518444, ENST00000347328, ENST00000522085, ENST00000518561, | ENST00000289004, ENST00000543163, ENST00000543869, | |
| Fusion gene scores | * DoF score | 8 X 4 X 6=192 | 4 X 4 X 3=48 |
| # samples | 8 | 4 | |
| ** MAII score | log2(8/192*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LARP4 [Title/Abstract] AND HPD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-YL-A8HO-01A | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000293618 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000293618 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000293618 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000429001 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000429001 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000429001 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000398473 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000398473 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000398473 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000518444 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000518444 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000518444 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000347328 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000347328 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000347328 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000522085 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000522085 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000522085 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000518561 | ENST00000289004 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| In-frame | ENST00000518561 | ENST00000543163 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
| 5CDS-5UTR | ENST00000518561 | ENST00000543869 | LARP4 | chr12 | 50824353 | + | HPD | chr12 | 122285120 | - |
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FusionProtFeatures for LARP4_HPD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LARP4 | HPD |
| RNA binding protein that binds to the poly-A tract ofmRNA molecules (PubMed:21098120). Associates with the 40Sribosomal subunit and with polysomes (PubMed:21098120). Plays arole in the regulation of mRNA translation (PubMed:21098120).Plays a role in the regulation of cell morphology and cytoskeletalorganization (PubMed:21834987, PubMed:27615744).{ECO:0000269|PubMed:21098120, ECO:0000269|PubMed:21834987,ECO:0000269|PubMed:27615744}. | Key enzyme in the degradation of tyrosine. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >HPD | chr12:50824353 | chr12:122285120 | ENST00000543163 | - | 9 | 15 | 180_338 | 159 | 355 | Domain | VOC 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000293618 | + | 4 | 15 | 113_202 | 132 | 654 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000293618 | + | 4 | 15 | 203_281 | 132 | 654 | Domain | Note=RRM |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000347328 | + | 4 | 15 | 113_202 | 132 | 654 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000347328 | + | 4 | 15 | 203_281 | 132 | 654 | Domain | Note=RRM |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000398473 | + | 4 | 16 | 113_202 | 132 | 725 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000398473 | + | 4 | 16 | 203_281 | 132 | 725 | Domain | Note=RRM |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000429001 | + | 4 | 16 | 113_202 | 138 | 731 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000429001 | + | 4 | 16 | 203_281 | 138 | 731 | Domain | Note=RRM |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000518444 | + | 4 | 16 | 113_202 | 131 | 724 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000518444 | + | 4 | 16 | 203_281 | 131 | 724 | Domain | Note=RRM |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000522085 | + | 4 | 11 | 113_202 | 132 | 446 | Domain | HTH La-type RNA-binding |
| Hgene | >LARP4 | chr12:50824353 | chr12:122285120 | ENST00000522085 | + | 4 | 11 | 203_281 | 132 | 446 | Domain | Note=RRM |
| Tgene | HPD | chr12:50824353 | chr12:122285120 | ENST00000543163 | - | 9 | 15 | 18_149 | 159 | 355 | Domain | VOC 1 |
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FusionGeneSequence for LARP4_HPD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_334aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEVSVFNTGNAELSEDICKEYEVMYSSSCETTRNTTG IEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKG >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_334aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEVSVFNTGNAELSEDICKEYEVMYSSSCETTRNTTG IEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKG >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_327aa MLLFVEVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDG MILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGK KKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFT >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_327aa MLLFVEVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDG MILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGK KKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFT >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_328aa MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTD GMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIF >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_258aa MYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRS IVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDA >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_258aa MYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRYLKNLQFHRFWSVDDTQVHTEYSSLRS IVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1002nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGTGTCTGTCTTTAAT ACAGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGC ATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTT TCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGG TCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATC AATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAG ACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGG GAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGC TACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGA GCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTG >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1002nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGTGTCTGTCTTTAAT ACAGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGC ATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTT TCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGG TCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATC AATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAG ACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGG GAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGC TACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGA GCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTG >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_981nt ATGTTGCTTTTCGTGGAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGAT GCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTCTCA GAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGG ATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAA TGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTG CACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAG AAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCG ATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAG ATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACC AAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTG >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_981nt ATGTTGCTTTTCGTGGAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGAT GCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTCTCA GAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGG ATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAA TGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTG CACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAG AAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCG ATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAG ATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACC AAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTG >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_984nt ATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACT GATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTC TCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGAT GGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAA GAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAG GTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGC AAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACA GCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCC AAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTC ACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCA >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_774nt ATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGT TACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGT TTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCC ATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTG GACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTG GAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCC CTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTC TTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAAC >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_774nt ATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGT TACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGT TTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCC ATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTG GACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTG GAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCC CTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTC TTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1387nt AGACCCGGAAGCAGTTGTTGTTTCAAGGGAGGTGGGACTGGGCGGGTCAGGCCGCAGCGGCTGACGGCAGGGGAGGAGCCGGGTCCACTG CCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACG ATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCA AGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCA TCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTAC AGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGC AGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTT CTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCC CATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCT CAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACT GCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAA AGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTT TGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGT GGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTAC TGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCT >In-frame_LARP4_ENST00000293618_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1384nt AGACCCGGAAGCAGTTGTTGTTTCAAGGGAGGTGGGACTGGGCGGGTCAGGCCGCAGCGGCTGACGGCAGGGGAGGAGCCGGGTCCACTG CCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACG ATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCA AGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCA TCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTAC AGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGC AGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTT CTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCC CATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCT CAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACT GCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAA AGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTT TGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGT GGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTAC TGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCT >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1357nt AGGCCGCAGCGGCTGACGGCAGGGGAGGAGCCGGGTCCACTGCCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGG GCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGC ATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAAC TGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGTGTCTGTCTTTAATACAGGTAATGCAGAGCTCTCAGAAGA TATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGAT TTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCT GAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACAC GGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAA GTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCG CCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAA GGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACC GGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAA GGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCC ACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAG CGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCCCTCCCGATTAAAGCGTGCCCC >In-frame_LARP4_ENST00000429001_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1354nt AGGCCGCAGCGGCTGACGGCAGGGGAGGAGCCGGGTCCACTGCCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGG GCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGC ATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAAC TGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGTGTCTGTCTTTAATACAGGTAATGCAGAGCTCTCAGAAGA TATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGAT TTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCT GAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACAC GGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAA GTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCG CCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAA GGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACC GGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAA GGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCC ACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAG CGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCCCTCCCGATTAAAGCGTGCCCC >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1297nt CCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACG ATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCA AGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCA TCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTAC AGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGC AGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTT CTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCC CATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCT CAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACT GCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAA AGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTT TGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGT GGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTAC TGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCT >In-frame_LARP4_ENST00000398473_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1294nt CCGGGTGGAGGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACG ATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCA AGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCA TCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTAC AGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGC AGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTT CTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCC CATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCT CAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACT GCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAA AGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTT TGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGT GGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTAC TGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCT >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1264nt CTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCT TTTCGTGGAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCC AGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTCTCAGAAGATAT ATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGATTTT AGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAA GAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGA ATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTC CCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCGCCA CTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGT GAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGT GCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGC TTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCCACG GAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGG ACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCCCTCCCGATTAAAGCGTGCCCCGGT >In-frame_LARP4_ENST00000518444_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1261nt CTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCT TTTCGTGGAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCC AGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGGTAATGCAGAGCTCTCAGAAGATAT ATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGAAGAATCAACTGATGGGATGATTTT AGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAA GAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGA ATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTC CCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGAAGACATCATCACAGCGATTCGCCA CTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGT GAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGT GCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGC TTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCCACG GAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGG ACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCCCTCCCGATTAAAGCGTGCCCCGGT >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1211nt AACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTAT GGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTG CTCATCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATA CTACAGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATT CAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACC GCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGA TGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCG CTCTCAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAAC AACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACG AGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGG GTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATG GGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCC CTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCC >In-frame_LARP4_ENST00000347328_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1208nt AACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTAT GGCAAGAAATTGCTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTG CTCATCCTGAGGGTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATA CTACAGGCATTGAAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATT CAGCAGTTTCTACAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACC GCTTCTGGTCCGTGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGA TGCCCATCAATGAGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCG CTCTCAAGACCGAAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAAC AACTGCGGGAGAAGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACG AGAAAGGCTACCTCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGG GTTTTGGAGCCGGCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATG GGGTGGTGCCCGGCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCC CTACTGGCTGCTCCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCC >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1288nt GGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTG AGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGC TCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGG TAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGA AGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTAC AGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGT GGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGA GCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGA AGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAA GCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCT CCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGG CAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGG CATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTC CCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCC >In-frame_LARP4_ENST00000522085_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1285nt GGGGCAAGGCGAGTGTGTGTCCTTATCCTAGCAATTGGGGCGCGGGCCTGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTG AGCAGAGGACGACATGTTGCTTTTCGTGGAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTGC TCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGGG TAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTGA AGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTAC AGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCGT GGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATGA GCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCGA AGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGAA GCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACCT CCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCGG CAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCGG CATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCTC CCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGCC >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000289004_chr12_122285120_-_1289nt TGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCATTTATGGGGTTAAGT GGCATGGGATTTCTGTTTCTGATAGTAAATAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTG CTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGG GTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTG AAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTA CAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCG TGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATG AGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCG AAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGA AGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACC TCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCG GCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCG GCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCT CCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGC >In-frame_LARP4_ENST00000518561_chr12_50824353_+_HPD_ENST00000543163_chr12_122285120_-_1286nt TGTGAGCCAGTTGGAGTTGCGGCGGCGGGAACGATTGGGCTGAGCAGAGGACGACATGTTGCTTTTCGTGGAGCATTTATGGGGTTAAGT GGCATGGGATTTCTGTTTCTGATAGTAAATAGCAGGTAGCATCTAAAGGAACTGGTTTAAATCCTAATGCCAAAGTATGGCAAGAAATTG CTCCTGGAAATACTGATGCCACCCCAGTAACTCATGGAACTGAAAGCTCTTGGCATGAAATAGCAGCTACATCAGGTGCTCATCCTGAGG GTAATGCAGAGCTCTCAGAAGATATATGTAAAGAATATGAAGTAATGTATTCTTCATCTTGTGAAACCACAAGAAATACTACAGGCATTG AAGAATCAACTGATGGGATGATTTTAGGACCAGAAGATCTGAGTTACCAAATATATGATGTTTCCGGAGAAAGCAATTCAGCAGTTTCTA CAGAAGACCTAAAAGAATGTCTGAAGAAACAATTAGAATTCTGTTTTTCACGGTACCTGAAAAACCTGCAGTTCCACCGCTTCTGGTCCG TGGATGACACGCAGGTGCACACGGAATATAGCTCTCTGCGATCCATTGTGGTGGCCAACTATGAAGAGTCCATCAAGATGCCCATCAATG AGCCAGCGCCTGGCAAGAAGAAGTCCCAGATCCAGGAATATGTGGACTATAACGGGGGCGCTGGGGTCCAGCACATCGCTCTCAAGACCG AAGACATCATCACAGCGATTCGCCACTTGAGAGAGAGAGGCCTGGAGTTCTTATCTGTTCCCTCCACGTACTACAAACAACTGCGGGAGA AGCTGAAGACGGCCAAGATCAAGGTGAAGGAGAACATTGATGCCCTGGAGGAGCTGAAAATCCTGGTGGACTACGACGAGAAAGGCTACC TCCTGCAGATCTTCACCAAACCGGTGCAGGACCGGCCCACGCTCTTCCTGGAAGTCATCCAGCGCCACAACCACCAGGGTTTTGGAGCCG GCAACTTCAACTCACTGTTCAAGGCTTTCGAGGAGGAGCAGAACCTGCGGGGTAACCTCACCAACATGGAGACCAATGGGGTGGTGCCCG GCATGTAAGCCCCGCCCACCCCACGGAGGCCACAGCCACACAGCCACGCCCCCTGATTCTGGAACTCGCCCAACTTCCCTACTGGCTGCT CCCCTTGGGTCCCGCCCACCAGCGGACTCGGCCCCCAAGGCTCCGCCCACACTGACCACGCCCCTCGGCGGGGCCGCCCTCTGCTCCAGC |
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FusionGenePPI for LARP4_HPD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LARP4 | ELAVL1, SIRT7, CUL3, COPS6, APP, MPG, TARDBP, LIN28A, LIN28B, CRX, BHLHE40, EGFR, GNB2L1, NTRK1, MYO1C, NPM1, RPL10, AKAP1, RNF126, G3BP1 | HPD | HIVEP1, CDKN1A, IKBKG, HRSP12, ASPSCR1, RBMX |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000293618 | + | 4 | 15 | 13_22 | 132 | 654 | PABPC1 |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000347328 | + | 4 | 15 | 13_22 | 132 | 654 | PABPC1 |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000398473 | + | 4 | 16 | 13_22 | 132 | 725 | PABPC1 |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000429001 | + | 4 | 16 | 13_22 | 138 | 731 | PABPC1 |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000518444 | + | 4 | 16 | 13_22 | 131 | 724 | PABPC1 |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000522085 | + | 4 | 11 | 13_22 | 132 | 446 | PABPC1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000293618 | + | 4 | 15 | 111_303 | 132 | 654 | the poly-A tract of mRNA |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000347328 | + | 4 | 15 | 111_303 | 132 | 654 | the poly-A tract of mRNA |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000398473 | + | 4 | 16 | 111_303 | 132 | 725 | the poly-A tract of mRNA |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000429001 | + | 4 | 16 | 111_303 | 138 | 731 | the poly-A tract of mRNA |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000518444 | + | 4 | 16 | 111_303 | 131 | 724 | the poly-A tract of mRNA |
| Hgene | LARP4 | chr12:50824353 | chr12:122285120 | ENST00000522085 | + | 4 | 11 | 111_303 | 132 | 446 | the poly-A tract of mRNA |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LARP4_HPD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | HPD | P32754 | DB00348 | Nitisinone | 4-hydroxyphenylpyruvate dioxygenase | small molecule | approved|investigational |
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RelatedDiseases for LARP4_HPD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | LARP4 | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| Tgene | HPD | C0268623 | Tyrosinemia, Type III | 2 | ORPHANET;UNIPROT |
| Tgene | HPD | C4277682 | Chemical and Drug Induced Liver Injury | 2 | CTD_human |
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