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Fusion gene ID: 19433 |
FusionGeneSummary for LANCL2_TTC3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LANCL2_TTC3 | Fusion gene ID: 19433 | Hgene | Tgene | Gene symbol | LANCL2 | TTC3 | Gene ID | 55915 | 7267 |
| Gene name | LanC like 2 | tetratricopeptide repeat domain 3 | |
| Synonyms | GPR69B|TASP | DCRR1|RNF105|TPRDIII | |
| Cytomap | 7p11.2 | 21q22.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lanC-like protein 2G protein-coupled receptor 69BLanC (bacterial lantibiotic synthetase component C)-like 2LanC lantibiotic synthetase component C-like 2testis-specific adriamycin sensitivity protein | E3 ubiquitin-protein ligase TTC3RING finger protein 105RING-type E3 ubiquitin transferase TTC3TPR repeat protein 3TPR repeat protein Dtetratricopeptide repeat protein 3 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q9NS86 | P53804 | |
| Ensembl transtripts involved in fusion gene | ENST00000254770, ENST00000486376, | ENST00000355666, ENST00000399017, ENST00000354749, ENST00000479930, ENST00000540756, ENST00000399010, | |
| Fusion gene scores | * DoF score | 5 X 4 X 5=100 | 9 X 12 X 7=756 |
| # samples | 6 | 14 | |
| ** MAII score | log2(6/100*10)=-0.736965594166206 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(14/756*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LANCL2 [Title/Abstract] AND TTC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | LANCL2 | GO:0009789 | positive regulation of abscisic acid-activated signaling pathway | 19667068 |
| Hgene | LANCL2 | GO:0045892 | negative regulation of transcription, DNA-templated | 12566319 |
| Tgene | TTC3 | GO:0006511 | ubiquitin-dependent protein catabolic process | 20059950 |
| Tgene | TTC3 | GO:0070936 | protein K48-linked ubiquitination | 20059950 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-E1-A7YQ-01A | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000254770 | ENST00000355666 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| In-frame | ENST00000254770 | ENST00000399017 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| In-frame | ENST00000254770 | ENST00000354749 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| 5CDS-3UTR | ENST00000254770 | ENST00000479930 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| 5CDS-intron | ENST00000254770 | ENST00000540756 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| 5CDS-intron | ENST00000254770 | ENST00000399010 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-3CDS | ENST00000486376 | ENST00000355666 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-3CDS | ENST00000486376 | ENST00000399017 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-3CDS | ENST00000486376 | ENST00000354749 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-3UTR | ENST00000486376 | ENST00000479930 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-intron | ENST00000486376 | ENST00000540756 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
| intron-intron | ENST00000486376 | ENST00000399010 | LANCL2 | chr7 | 55433922 | + | TTC3 | chr21 | 38544897 | + |
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FusionProtFeatures for LANCL2_TTC3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LANCL2 | TTC3 |
| Necessary for abscisic acid (ABA) binding on the cellmembrane and activation of the ABA signaling pathway ingranulocytes. {ECO:0000269|PubMed:19667068}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1563_1579 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1899_1902 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1563_1579 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1899_1902 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1563_1579 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1899_1902 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1957_1997 | 1489 | 2026 | Zinc finger | RING-type |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1957_1997 | 1489 | 2026 | Zinc finger | RING-type |
| Tgene | >TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1957_1997 | 1489 | 2026 | Zinc finger | RING-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1018_1029 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1020_1029 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 1172_1185 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 453_456 | 1489 | 2026 | Compositional bias | Note=Poly-Ser |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1018_1029 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1020_1029 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 1172_1185 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 453_456 | 1489 | 2026 | Compositional bias | Note=Poly-Ser |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1018_1029 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1020_1029 | 1489 | 2026 | Compositional bias | Note=Poly-Lys |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 1172_1185 | 1489 | 2026 | Compositional bias | Note=Arg/Lys-rich (basic) |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 453_456 | 1489 | 2026 | Compositional bias | Note=Poly-Ser |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 231_264 | 1489 | 2026 | Repeat | Note=TPR 1 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 266_298 | 1489 | 2026 | Repeat | Note=TPR 2 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 536_572 | 1489 | 2026 | Repeat | Note=TPR 3 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000354749 | + | 32 | 45 | 576_609 | 1489 | 2026 | Repeat | Note=TPR 4 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 231_264 | 1489 | 2026 | Repeat | Note=TPR 1 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 266_298 | 1489 | 2026 | Repeat | Note=TPR 2 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 536_572 | 1489 | 2026 | Repeat | Note=TPR 3 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000355666 | + | 33 | 46 | 576_609 | 1489 | 2026 | Repeat | Note=TPR 4 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 231_264 | 1489 | 2026 | Repeat | Note=TPR 1 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 266_298 | 1489 | 2026 | Repeat | Note=TPR 2 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 536_572 | 1489 | 2026 | Repeat | Note=TPR 3 |
| Tgene | TTC3 | chr7:55433922 | chr21:38544897 | ENST00000399017 | + | 33 | 46 | 576_609 | 1489 | 2026 | Repeat | Note=TPR 4 |
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FusionGeneSequence for LANCL2_TTC3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000355666_chr21_38544897_+_605aa MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKGEISRIEKEHQVLQDQLQEVYE NYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELH LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE LFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGD SPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVR SKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICH >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000399017_chr21_38544897_+_605aa MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKGEISRIEKEHQVLQDQLQEVYE NYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELH LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE LFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGD SPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVR SKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICH >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000354749_chr21_38544897_+_605aa MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKGEISRIEKEHQVLQDQLQEVYE NYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELH LDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWE LFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGD SPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVR SKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000355666_chr21_38544897_+_1815nt ATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAGAAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGAC TACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAGGCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGC CTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGCACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAA AATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAGAGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCA AAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAATGGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAA TCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCCAGAAAAATGATGGAAAGGAAAAGGAACATGAATTACAT CTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAATAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAA GAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGAAGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCA CAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAGCATATCCTGACATGGAGTCTGATATACGTTCATGGGAA TTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTGAAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTC AGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACACGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGAC GATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAGCACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGAT TCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGCCTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGC CAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTCCTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAA AAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACAACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGA AGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAAGAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAA AAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCCCCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTT GTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGAGGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCAC GAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATCACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGC GCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTGGAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCC >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000399017_chr21_38544897_+_1815nt ATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAGAAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGAC TACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAGGCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGC CTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGCACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAA AATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAGAGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCA AAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAATGGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAA TCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCCAGAAAAATGATGGAAAGGAAAAGGAACATGAATTACAT CTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAATAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAA GAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGAAGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCA CAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAGCATATCCTGACATGGAGTCTGATATACGTTCATGGGAA TTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTGAAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTC AGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACACGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGAC GATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAGCACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGAT TCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGCCTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGC CAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTCCTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAA AAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACAACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGA AGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAAGAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAA AAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCCCCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTT GTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGAGGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCAC GAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATCACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGC GCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTGGAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCC >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000354749_chr21_38544897_+_1815nt ATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAGAAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGAC TACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAGGCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGC CTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGCACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAA AATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAGAGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCA AAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAATGGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAA TCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCCAGAAAAATGATGGAAAGGAAAAGGAACATGAATTACAT CTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAATAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAA GAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGAAGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCA CAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAGCATATCCTGACATGGAGTCTGATATACGTTCATGGGAA TTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTGAAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTC AGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACACGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGAC GATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAGCACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGAT TCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGCCTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGC CAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTCCTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAA AAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACAACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGA AGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAAGAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAA AAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCCCCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTT GTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGAGGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCAC GAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATCACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGC GCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTGGAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000355666_chr21_38544897_+_3922nt GGGCTGGCGCAGCAGGGGCCGGTGAAATGCAGGCTGACGACGGCGCGCCAGGGGCTGAGCTCGCCCCGGTCGGCGACGCGCACACACCTT GAGTGACAGCGACCTCTTCTCTACAGGTTTTCCCCGCGGGAGCGTGGCCCTAGCGGGCGTTCGGTTTTCTTTGGAAATCGCGGAGGGGGC TGGCCGGGCGCAGCGATCCCCACCCCGGGACTCCAGCCCCGGCCGTGCGCGTCGCCGCGGACGGGCTCTGCGGGCCACGGGGAAGGTGCG AGGAGGCGCGAGCAGGCTGTGAGCCGCTGGGCGCTCCCGCGAGCCCGCTCCTCTCCGTCGGGAGCAGGGCAAAGGCGCCAGGAACAGGGC AGAGGCACAGCGCCCACCGCCTCTGCGGCCGCCTGATGTGCGAGCAGCCCGCGACGAGGCAGTGCACGCTCAGACGCCCCGCTCCTCCCG CCAGCGCGCGGCCTCGCTCCTCCTAGAGGACGCTCTCTGCGCGGGCCCTCGGAGGAGGCGGCGGCGGGGCGAGCTGCAGCGCCGGGACAG GAGGTTTGTCCCCGCCCGCGCGCCGTACCGCGGCGGAGATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAG AAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGACTACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAG GCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGCCTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGC ACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAAAATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAG AGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCAAAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAAT GGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAATCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCC AGAAAAATGATGGAAAGGAAAAGGAACATGAATTACATCTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAA TAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAAGAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGA AGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCACAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAG CATATCCTGACATGGAGTCTGATATACGTTCATGGGAATTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTG AAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTCAGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACA CGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGACGATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAG CACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGATTCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGC CTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGCCAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTC CTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAAAAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACA ACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGAAGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAA GAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAAAAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCC CCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTTGTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGA GGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCACGAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATC ACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGCGCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTG GAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCCTGCTCTTCTAGGTAGTCACACTTCACTAAAGTGTCATCCACCAGTGTGTTGA ATCCGAAGAATGACAATTTTCTACCACTGGTGTAAAAAACAAACATTTGAAGACCCTTGTGCATTGTGTGTCACAAAGCTAAATACATGG AAATCGTTAATATCGCTGATATTAAGTAATTTCCCCACTCTGAGTGAATACTTTGATGATTGCCAACAGTGGCTAATAAAATGACGGCTA CCACACTCATGGGTCACTGGGGCTGCGCAGGGCTCTTTGAGGTGGGTGGCTTCTTTTGGAAAGTACTATGAACGTCTCGAAGCAGTATTC TAGTGATAAGAATTCTTAACATAGCCAAGCGCCCCACGTTTGTTCCCCACGTTTGTTCCCCTTTTCTGTTTGAAAAACCTGTTCTGGTAG CTCCACAAGAGAGATGATACTGACTTTTTAAATTTTTTACAAGAGTCTGTATTCCTGATATGCCTATATTTTTCCTCAAAGATTCTGCAT TTTAAGGATGGGCATAAGCAAACTATATTTTAATAATTTATAGTTAATGTTAAAATATTGGCTGATTTAGACCAAAAGATTCAAATCTCC TCTTTGTGAAATCCCATCTGCATTTGATTTTTTATTATTTTATGTTCCCCCGTTAGATTGTTTTAAGTGTTTGCTTTTCATCTTTTATAG ATGTAATCTGATTTTCAAAAATCATTAACACTTTTTAATTAGTATCGACTAAGACTTTTTCCCCCTGGAATCGAGGCTGTGTGTCCGTCA TCCCAGCCCCCGGTTGGAGCCTGCTCTTTGAACTCCGCTGCCTTCCTTAGCAGCTTCTGTCCTCTTCTGTGAGTCAGTCAGCGAGTGCTT GGGATCCGCATCCAGCCGTGCTGAGCACACAACAGGCTGTGTGTGGAAATGGCCACCACCATTCTCCTTCCCCACCCCACCACAAAAAGA GAAGCTGTGTCTTTAGACAACCCTGAGGTATCTGTGTTACAATCGTTCTGTGTTTGATATTTGTGTAAAGTATGCATGCAGTCTTGTACT GTGACCTAAGAACAAAACTGTAACTGCATTAGAAACCATGAAAAAATTAGATATTGTTTTGTGACTTTTAGACAGTGGTAAATATAGAAC CATGAATTCTGGTCACATTCCATTTCTCTCCAACATGAAGGATCAAAAAATGTTTTTCAATGTGTTCTTTGTTCCACTGGAAACTTAGAG TCATGAGTTTATGAGCTGATTTGGTCACCTTCCTCTGCCTTTGTTCACTGTGAGTTCTGATGTCTTAGTGACTTAGTTCTTAGAAGCTCA CGCCTTAGTTTGAAACAGATTCTCCACGGTGGTCCCCAAAACACTGTCTGCATATCCATAAGAATTGAGCGCTATGGGTGTTAACGTGCA TGAGGATCAGTTTGCAGCAGCAAGTACAAAAGGAGAAGAGGAACATCCGTTGAATGAGTGTGTTTTGTACATAACTTCAGATACTTGTGA >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000399017_chr21_38544897_+_3931nt GGGCTGGCGCAGCAGGGGCCGGTGAAATGCAGGCTGACGACGGCGCGCCAGGGGCTGAGCTCGCCCCGGTCGGCGACGCGCACACACCTT GAGTGACAGCGACCTCTTCTCTACAGGTTTTCCCCGCGGGAGCGTGGCCCTAGCGGGCGTTCGGTTTTCTTTGGAAATCGCGGAGGGGGC TGGCCGGGCGCAGCGATCCCCACCCCGGGACTCCAGCCCCGGCCGTGCGCGTCGCCGCGGACGGGCTCTGCGGGCCACGGGGAAGGTGCG AGGAGGCGCGAGCAGGCTGTGAGCCGCTGGGCGCTCCCGCGAGCCCGCTCCTCTCCGTCGGGAGCAGGGCAAAGGCGCCAGGAACAGGGC AGAGGCACAGCGCCCACCGCCTCTGCGGCCGCCTGATGTGCGAGCAGCCCGCGACGAGGCAGTGCACGCTCAGACGCCCCGCTCCTCCCG CCAGCGCGCGGCCTCGCTCCTCCTAGAGGACGCTCTCTGCGCGGGCCCTCGGAGGAGGCGGCGGCGGGGCGAGCTGCAGCGCCGGGACAG GAGGTTTGTCCCCGCCCGCGCGCCGTACCGCGGCGGAGATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAG AAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGACTACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAG GCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGCCTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGC ACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAAAATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAG AGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCAAAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAAT GGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAATCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCC AGAAAAATGATGGAAAGGAAAAGGAACATGAATTACATCTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAA TAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAAGAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGA AGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCACAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAG CATATCCTGACATGGAGTCTGATATACGTTCATGGGAATTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTG AAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTCAGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACA CGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGACGATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAG CACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGATTCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGC CTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGCCAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTC CTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAAAAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACA ACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGAAGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAA GAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAAAAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCC CCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTTGTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGA GGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCACGAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATC ACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGCGCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTG GAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCCTGCTCTTCTAGGTAGTCACACTTCACTAAAGTGTCATCCACCAGTGTGTTGA ATCCGAAGAATGACAATTTTCTACCACTGGTGTAAAAAACAAACATTTGAAGACCCTTGTGCATTGTGTGTCACAAAGCTAAATACATGG AAATCGTTAATATCGCTGATATTAAGTAATTTCCCCACTCTGAGTGAATACTTTGATGATTGCCAACAGTGGCTAATAAAATGACGGCTA CCACACTCATGGGTCACTGGGGCTGCGCAGGGCTCTTTGAGGTGGGTGGCTTCTTTTGGAAAGTACTATGAACGTCTCGAAGCAGTATTC TAGTGATAAGAATTCTTAACATAGCCAAGCGCCCCACGTTTGTTCCCCACGTTTGTTCCCCTTTTCTGTTTGAAAAACCTGTTCTGGTAG CTCCACAAGAGAGATGATACTGACTTTTTAAATTTTTTACAAGAGTCTGTATTCCTGATATGCCTATATTTTTCCTCAAAGATTCTGCAT TTTAAGGATGGGCATAAGCAAACTATATTTTAATAATTTATAGTTAATGTTAAAATATTGGCTGATTTAGACCAAAAGATTCAAATCTCC TCTTTGTGAAATCCCATCTGCATTTGATTTTTTATTATTTTATGTTCCCCCGTTAGATTGTTTTAAGTGTTTGCTTTTCATCTTTTATAG ATGTAATCTGATTTTCAAAAATCATTAACACTTTTTAATTAGTATCGACTAAGACTTTTTCCCCCTGGAATCGAGGCTGTGTGTCCGTCA TCCCAGCCCCCGGTTGGAGCCTGCTCTTTGAACTCCGCTGCCTTCCTTAGCAGCTTCTGTCCTCTTCTGTGAGTCAGTCAGCGAGTGCTT GGGATCCGCATCCAGCCGTGCTGAGCACACAACAGGCTGTGTGTGGAAATGGCCACCACCATTCTCCTTCCCCACCCCACCACAAAAAGA GAAGCTGTGTCTTTAGACAACCCTGAGGTATCTGTGTTACAATCGTTCTGTGTTTGATATTTGTGTAAAGTATGCATGCAGTCTTGTACT GTGACCTAAGAACAAAACTGTAACTGCATTAGAAACCATGAAAAAATTAGATATTGTTTTGTGACTTTTAGACAGTGGTAAATATAGAAC CATGAATTCTGGTCACATTCCATTTCTCTCCAACATGAAGGATCAAAAAATGTTTTTCAATGTGTTCTTTGTTCCACTGGAAACTTAGAG TCATGAGTTTATGAGCTGATTTGGTCACCTTCCTCTGCCTTTGTTCACTGTGAGTTCTGATGTCTTAGTGACTTAGTTCTTAGAAGCTCA CGCCTTAGTTTGAAACAGATTCTCCACGGTGGTCCCCAAAACACTGTCTGCATATCCATAAGAATTGAGCGCTATGGGTGTTAACGTGCA TGAGGATCAGTTTGCAGCAGCAAGTACAAAAGGAGAAGAGGAACATCCGTTGAATGAGTGTGTTTTGTACATAACTTCAGATACTTGTGA >In-frame_LANCL2_ENST00000254770_chr7_55433922_+_TTC3_ENST00000354749_chr21_38544897_+_3931nt GGGCTGGCGCAGCAGGGGCCGGTGAAATGCAGGCTGACGACGGCGCGCCAGGGGCTGAGCTCGCCCCGGTCGGCGACGCGCACACACCTT GAGTGACAGCGACCTCTTCTCTACAGGTTTTCCCCGCGGGAGCGTGGCCCTAGCGGGCGTTCGGTTTTCTTTGGAAATCGCGGAGGGGGC TGGCCGGGCGCAGCGATCCCCACCCCGGGACTCCAGCCCCGGCCGTGCGCGTCGCCGCGGACGGGCTCTGCGGGCCACGGGGAAGGTGCG AGGAGGCGCGAGCAGGCTGTGAGCCGCTGGGCGCTCCCGCGAGCCCGCTCCTCTCCGTCGGGAGCAGGGCAAAGGCGCCAGGAACAGGGC AGAGGCACAGCGCCCACCGCCTCTGCGGCCGCCTGATGTGCGAGCAGCCCGCGACGAGGCAGTGCACGCTCAGACGCCCCGCTCCTCCCG CCAGCGCGCGGCCTCGCTCCTCCTAGAGGACGCTCTCTGCGCGGGCCCTCGGAGGAGGCGGCGGCGGGGCGAGCTGCAGCGCCGGGACAG GAGGTTTGTCCCCGCCCGCGCGCCGTACCGCGGCGGAGATGGGCGAGACCATGTCAAAGAGGCTGAAGCTCCACCTGGGAGGGGAGGCAG AAATGGAGGAACGGGCGTTCGTCAACCCCTTCCCGGACTACGAGGCCGCCGCCGGGGCGCTGCTCGCCTCCGGAGCGGCCGAAGAGACAG GCTGTGTTCGTCCCCCGGCGACCACGGATGAGCCCGGCCTCCCTTTTCATCAGGACGGGAAGGGGGAAATTTCACGGATTGAAAAGGAGC ACCAAGTATTACAAGACCAACTTCAAGAAGTGTATGAAAATTATGAGCAGATAAAACTTAAGGGCTTAGAAGAGACCAGGGACCTGGAAG AGAAGTTGAAAAGGCACTTAGAAGAAAACAAGATCTCAAAGACGGAATTAGATTGGTTCCTTCAAGATTTGGAAAGAGAAATTAAAAAAT GGCAACAGGAAAAAAAAGAAATCCAAGAAAGACTAAAATCACTGAAGAAGAAAATTAAAAAGGTTTCAAATGCCAGTGAAATGTATACCC AGAAAAATGATGGAAAGGAAAAGGAACATGAATTACATCTGGATCAGTCCCTTGAAATCAGCAACACACTTACAAATGAGAAAATGAAAA TAGAAGAGTATATAAAGAAAGGGAAAGAGGATTATGAAGAGAGTCATCAGAGAGCTGTGGCTGCAGAGGTATCCGTACTTGAAAACTGGA AGGAGAGTGAAGTGTATAAGCTACAGATCATGGAGTCACAAGCAGAAGCCTTTCTGAAGAAGCTGGGGCTGATTAGCCGTGATCCTGCAG CATATCCTGACATGGAGTCTGATATACGTTCATGGGAATTGTTTCTTTCTAATGTTACAAAAGAAATTGAGAAAGCAAAGTCTCAGTTTG AAGAACAAATTAAGGCAATTAAAAATGGTTCTCGGCTCAGTGAACTTTCTAAAGTGCAGATTTCTGAGCTTTCATTTCCTGCCTGTAACA CGGTTCATCCCGAGTTACTCCCTGAGTCTTCAGGCGACGATGGCCAAGGGCTTGTGACTTCTGCAAGCGACGTGACTGGAAACCACGCAG CACTTCACAGGGATCCTAGTGTGTTCTCTGCTGGTGATTCCCCAGGGGAGGCTCCTTCTGCGCTGTTGCCAGGGCCACCCCCTGGTCAGC CTGAAGCCACTCAGCTGACAGGGCCAAAACGGGCTGGCCAGGCAGCTCTGTCAGAACGAAGCCCTGTGGCTGATCGGAAGCAGCCTGTTC CTCCAGGACGTGCTGCGCGTTCAAGCCAGTCTCCAAAAAAGCCGTTCAATAGTATTATTGAGCACCTGTCAGTGGTATTCCCATGTTACA ACAGCACTGAGCTTGCTGGTTTTATTAAAAAAGTGCGAAGCAAAAACAAGAACTCACTCTCAGGATTGAGTATTGATGAAATTGTCCAAA GAGTGACAGAACACATTCTAGATGAACAGAAAAAGAAAAAGCCAAACCCAGGAAAGGACAAGAGGACTTATGAGCCCAGCTCTGCCACCC CCGTGACCAGGTCCTCCCAGGGCTCACCCTCGGTGGTTGTTGCACCATCACCCAAAACCAAGGGGCAGAAAGCAGAAGATGTCCCTGTGA GGATTGCACTGGGTGCAAGTTCCTGTGAAATATGCCACGAGGTGTTCAAATCAAAAAACGTGCGTGTGCTCAAATGTGGGCACAAGTATC ACAAAGGGTGCTTTAAGCAGTGGCTTAAAGGGCAGAGCGCTTGCCCGGCCTGCCAGGGTCGTGATCTCCTGACAGAAGAGTCACCTTCTG GAAGAGGCTGGCCCAGTCAGAATCAGGAGCTGCCTTCCTGCTCTTCTAGGTAGTCACACTTCACTAAAGTGTCATCCACCAGTGTGTTGA ATCCGAAGAATGACAATTTTCTACCACTGGTGTAAAAAACAAACATTTGAAGACCCTTGTGCATTGTGTGTCACAAAGCTAAATACATGG AAATCGTTAATATCGCTGATATTAAGTAATTTCCCCACTCTGAGTGAATACTTTGATGATTGCCAACAGTGGCTAATAAAATGACGGCTA CCACACTCATGGGTCACTGGGGCTGCGCAGGGCTCTTTGAGGTGGGTGGCTTCTTTTGGAAAGTACTATGAACGTCTCGAAGCAGTATTC TAGTGATAAGAATTCTTAACATAGCCAAGCGCCCCACGTTTGTTCCCCACGTTTGTTCCCCTTTTCTGTTTGAAAAACCTGTTCTGGTAG CTCCACAAGAGAGATGATACTGACTTTTTAAATTTTTTACAAGAGTCTGTATTCCTGATATGCCTATATTTTTCCTCAAAGATTCTGCAT TTTAAGGATGGGCATAAGCAAACTATATTTTAATAATTTATAGTTAATGTTAAAATATTGGCTGATTTAGACCAAAAGATTCAAATCTCC TCTTTGTGAAATCCCATCTGCATTTGATTTTTTATTATTTTATGTTCCCCCGTTAGATTGTTTTAAGTGTTTGCTTTTCATCTTTTATAG ATGTAATCTGATTTTCAAAAATCATTAACACTTTTTAATTAGTATCGACTAAGACTTTTTCCCCCTGGAATCGAGGCTGTGTGTCCGTCA TCCCAGCCCCCGGTTGGAGCCTGCTCTTTGAACTCCGCTGCCTTCCTTAGCAGCTTCTGTCCTCTTCTGTGAGTCAGTCAGCGAGTGCTT GGGATCCGCATCCAGCCGTGCTGAGCACACAACAGGCTGTGTGTGGAAATGGCCACCACCATTCTCCTTCCCCACCCCACCACAAAAAGA GAAGCTGTGTCTTTAGACAACCCTGAGGTATCTGTGTTACAATCGTTCTGTGTTTGATATTTGTGTAAAGTATGCATGCAGTCTTGTACT GTGACCTAAGAACAAAACTGTAACTGCATTAGAAACCATGAAAAAATTAGATATTGTTTTGTGACTTTTAGACAGTGGTAAATATAGAAC CATGAATTCTGGTCACATTCCATTTCTCTCCAACATGAAGGATCAAAAAATGTTTTTCAATGTGTTCTTTGTTCCACTGGAAACTTAGAG TCATGAGTTTATGAGCTGATTTGGTCACCTTCCTCTGCCTTTGTTCACTGTGAGTTCTGATGTCTTAGTGACTTAGTTCTTAGAAGCTCA CGCCTTAGTTTGAAACAGATTCTCCACGGTGGTCCCCAAAACACTGTCTGCATATCCATAAGAATTGAGCGCTATGGGTGTTAACGTGCA TGAGGATCAGTTTGCAGCAGCAAGTACAAAAGGAGAAGAGGAACATCCGTTGAATGAGTGTGTTTTGTACATAACTTCAGATACTTGTGA |
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FusionGenePPI for LANCL2_TTC3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LANCL2 | OTUD5, TCF3, TERF2IP, TERF2, APP, MON1B, CDK9, EGFR, APPBP2, MOV10, NXF1, FAM188A, GSTM3, MCM2, NF2, RHOU, AIRE, DOK2, KCNJ5, PVR, GMFG, FEZ1, PCGF2 | TTC3 | AKT1, AKT2, AKT3, UBE3A, UBC, UBE2D2, HSPB1, CSNK2A2, RAB5C, FGFR1OP, WAPAL, PARD6A, SMC6, KIF18A, DSN1, KRBOX4, DYNC2LI1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | LANCL2 | chr7:55433922 | chr21:38544897 | ENST00000254770 | + | 1 | 9 | 2_15 | 68 | 451 | inositol phospholipids |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LANCL2_TTC3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LANCL2_TTC3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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