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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 19384

FusionGeneSummary for LAMB1_NRCAM

check button Fusion gene summary
Fusion gene informationFusion gene name: LAMB1_NRCAM
Fusion gene ID: 19384
HgeneTgene
Gene symbol

LAMB1

NRCAM

Gene ID

3912

4897

Gene namelaminin subunit beta 1neuronal cell adhesion molecule
SynonymsCLM|LIS5-
Cytomap

7q31.1

7q31.1

Type of geneprotein-codingprotein-coding
Descriptionlaminin subunit beta-1laminin B1 chainlaminin, beta 1neuronal cell adhesion moleculeNgCAM-related cell adhesion moleculeneuronal surface protein Bravo
Modification date2018052220180519
UniProtAcc

P07942

Q92823

Ensembl transtripts involved in fusion geneENST00000393561, ENST00000222399, 
ENST00000393560, ENST00000474380, 
ENST00000379028, ENST00000413765, 
ENST00000351718, ENST00000379024, 
ENST00000379022, ENST00000425651, 
ENST00000522550, 
Fusion gene scores* DoF score10 X 8 X 4=3203 X 3 X 3=27
# samples 104
** MAII scorelog2(10/320*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LAMB1 [Title/Abstract] AND NRCAM [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLAMB1

GO:0030335

positive regulation of cell migration

16289578

HgeneLAMB1

GO:0031175

neuron projection development

15894315

HgeneLAMB1

GO:0034446

substrate adhesion-dependent cell spreading

16236823

HgeneLAMB1

GO:0042476

odontogenesis

15894315

TgeneNRCAM

GO:0045162

clustering of voltage-gated sodium channels

14602817


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-X6-A8C6-01ALAMB1chr7

107626467

-NRCAMchr7

107800937

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000393561ENST00000379028LAMB1chr7

107626467

-NRCAMchr7

107800937

-
In-frameENST00000393561ENST00000413765LAMB1chr7

107626467

-NRCAMchr7

107800937

-
In-frameENST00000393561ENST00000351718LAMB1chr7

107626467

-NRCAMchr7

107800937

-
In-frameENST00000393561ENST00000379024LAMB1chr7

107626467

-NRCAMchr7

107800937

-
In-frameENST00000393561ENST00000379022LAMB1chr7

107626467

-NRCAMchr7

107800937

-
In-frameENST00000393561ENST00000425651LAMB1chr7

107626467

-NRCAMchr7

107800937

-
5CDS-intronENST00000393561ENST00000522550LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000379028LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000413765LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000351718LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000379024LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000379022LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000222399ENST00000425651LAMB1chr7

107626467

-NRCAMchr7

107800937

-
5CDS-intronENST00000222399ENST00000522550LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000379028LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000413765LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000351718LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000379024LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000379022LAMB1chr7

107626467

-NRCAMchr7

107800937

-
Frame-shiftENST00000393560ENST00000425651LAMB1chr7

107626467

-NRCAMchr7

107800937

-
5CDS-intronENST00000393560ENST00000522550LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000379028LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000413765LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000351718LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000379024LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000379022LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-3CDSENST00000474380ENST00000425651LAMB1chr7

107626467

-NRCAMchr7

107800937

-
intron-intronENST00000474380ENST00000522550LAMB1chr7

107626467

-NRCAMchr7

107800937

-

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FusionProtFeatures for LAMB1_NRCAM


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LAMB1

P07942

NRCAM

Q92823

Binding to cells via a high affinity receptor, lamininis thought to mediate the attachment, migration and organizationof cells into tissues during embryonic development by interactingwith other extracellular matrix components. Involved in theorganization of the laminar architecture of cerebral cortex. It isprobably required for the integrity of the basement membrane/glialimitans that serves as an anchor point for the endfeet of radialglial cells and as a physical barrier to migrating neurons. Radialglial cells play a central role in cerebral cortical development,where they act both as the proliferative unit of the cerebralcortex and a scaffold for neurons migrating toward the pialsurface. {ECO:0000269|PubMed:23472759}. Cell adhesion protein that is required for normalresponses to cell-cell contacts in brain and in the peripheralnervous system. Plays a role in neurite outgrowth in response tocontactin binding. Plays a role in mediating cell-cell contactsbetween Schwann cells and axons. Plays a role in the formation andmaintenance of the nodes of Ranvier on myelinated axons. Nodes ofRanvier contain clustered sodium channels that are crucial for thesaltatory propagation of action potentials along myelinated axons.During development, nodes of Ranvier are formed by the fusion oftwo heminodes. Required for normal clustering of sodium channelsat heminodes; not required for the formation of mature nodes withnormal sodium channel clusters. Required, together with GLDN, formaintaining NFASC and sodium channel clusters at mature nodes ofRanvier. {ECO:0000250|UniProtKB:Q810U4}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-24281064_115610341184DomainFibronectin type-III 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-26301064_115610431193DomainFibronectin type-III 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-24281191_130410341184Topological domainCytoplasmic
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-26301191_130410431193Topological domainCytoplasmic
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-29331191_130411551305Topological domainCytoplasmic
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-26301191_130411551305Topological domainCytoplasmic
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-24281168_119010341184TransmembraneHelical
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-26301168_119010431193TransmembraneHelical
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-29331168_119011551305TransmembraneHelical
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-26301168_119011551305TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341216_13152251787Coiled coilOntology_term=ECO:0000255
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341353_13882251787Coiled coilOntology_term=ECO:0000255
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341442_17812251787Coiled coilOntology_term=ECO:0000255
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341028_10832251787DomainLaminin EGF-like 11
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341084_11312251787DomainLaminin EGF-like 12
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341132_11782251787DomainLaminin EGF-like 13
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734271_3342251787DomainLaminin EGF-like 1
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-73431_2702251787DomainLaminin N-terminal
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734335_3972251787DomainLaminin EGF-like 2
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734398_4572251787DomainLaminin EGF-like 3
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734458_5092251787DomainLaminin EGF-like 4
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734510_5402251787DomainLaminin EGF-like 5%3B truncated
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734549_7672251787DomainLaminin IV type B
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734773_8202251787DomainLaminin EGF-like 6
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734821_8662251787DomainLaminin EGF-like 7
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734867_9162251787DomainLaminin EGF-like 8
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734917_9752251787DomainLaminin EGF-like 9
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-734976_10272251787DomainLaminin EGF-like 10
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341179_13972251787RegionNote=Domain II
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341398_14302251787RegionNote=Domain alpha
HgeneLAMB1chr7:107626467chr7:107800937ENST00000222399-7341431_17862251787RegionNote=Domain I
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428141_23510341184DomainNote=Ig-like 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428267_35610341184DomainNote=Ig-like 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428361_44810341184DomainNote=Ig-like 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428454_54110341184DomainNote=Ig-like 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-242846_13410341184DomainNote=Ig-like 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428545_63210341184DomainNote=Ig-like 6
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428649_74410341184DomainFibronectin type-III 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428746_84310341184DomainFibronectin type-III 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428848_95010341184DomainFibronectin type-III 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-2428954_105110341184DomainFibronectin type-III 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630141_23510431193DomainNote=Ig-like 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630267_35610431193DomainNote=Ig-like 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630361_44810431193DomainNote=Ig-like 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630454_54110431193DomainNote=Ig-like 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-263046_13410431193DomainNote=Ig-like 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630545_63210431193DomainNote=Ig-like 6
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630649_74410431193DomainFibronectin type-III 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630746_84310431193DomainFibronectin type-III 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630848_95010431193DomainFibronectin type-III 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-2630954_105110431193DomainFibronectin type-III 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-29331064_115611551305DomainFibronectin type-III 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933141_23511551305DomainNote=Ig-like 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933267_35611551305DomainNote=Ig-like 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933361_44811551305DomainNote=Ig-like 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933454_54111551305DomainNote=Ig-like 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-293346_13411551305DomainNote=Ig-like 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933545_63211551305DomainNote=Ig-like 6
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933649_74411551305DomainFibronectin type-III 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933746_84311551305DomainFibronectin type-III 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933848_95011551305DomainFibronectin type-III 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-2933954_105111551305DomainFibronectin type-III 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-26301064_115611551305DomainFibronectin type-III 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630141_23511551305DomainNote=Ig-like 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630267_35611551305DomainNote=Ig-like 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630361_44811551305DomainNote=Ig-like 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630454_54111551305DomainNote=Ig-like 5
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-263046_13411551305DomainNote=Ig-like 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630545_63211551305DomainNote=Ig-like 6
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630649_74411551305DomainFibronectin type-III 1
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630746_84311551305DomainFibronectin type-III 2
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630848_95011551305DomainFibronectin type-III 3
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-2630954_105111551305DomainFibronectin type-III 4
TgeneNRCAMchr7:107626467chr7:107800937ENST00000351718-242825_116710341184Topological domainExtracellular
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379024-263025_116710431193Topological domainExtracellular
TgeneNRCAMchr7:107626467chr7:107800937ENST00000379028-293325_116711551305Topological domainExtracellular
TgeneNRCAMchr7:107626467chr7:107800937ENST00000425651-263025_116711551305Topological domainExtracellular


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FusionGeneSequence for LAMB1_NRCAM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379028_chr7_107800937_-_399aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA
VALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQF

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000413765_chr7_107800937_-_399aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA
VALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQF

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000351718_chr7_107800937_-_399aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA
VALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQF

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379024_chr7_107800937_-_399aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA
VALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQF

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379022_chr7_107800937_-_331aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000425651_chr7_107800937_-_399aa
MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI
VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDF
GKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQTMASRQVDIATQGWFIGLMCA
VALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQF


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379028_chr7_107800937_-_1197nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGAAAAAA
GGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCCAGTTC
AATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTTCTCCT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000413765_chr7_107800937_-_1197nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGAAAAAA
GGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCCAGTTC
AATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTTCTCCT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000351718_chr7_107800937_-_1197nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGAAAAAA
GGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCCAGTTC
AATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTTCTCCT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379024_chr7_107800937_-_1197nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGAAAAAA
GGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCCAGTTC
AATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTTCTCCT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379022_chr7_107800937_-_993nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGGCTGTTTTCATTTGTTTCTTCTGCATCCTTT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000425651_chr7_107800937_-_1197nt
ATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTG
TTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTAT
CCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATC
GTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATCTCATT
GAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAACTGGAT
TTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCGACTTT
GGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAGTCGAT
GACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCAAAATA
GAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGTGTGCT
GTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAGATGCC
CATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGAAAAAA
GGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCCAGTTC
AATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTTCTCCT


* Fusion transcript sequences (Full-length transcript).
>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379028_chr7_107800937_-_3655nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGA
AAAAAGGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCC
AGTTCAATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTT
CTCCTGTCAACGCCATGAATTCCTTTGTTTAATTTTTAAGCTCTTTGCCAATATTCCATTTCTCTAGAATGTTTATCCTAAGCACTTGTT
TGTCAGCCCTCTCATACTATGAACATATGGGTAGAGAGTATATTTTCTGCTGTATGTTAGTATTATGAGAATAGTTACAGCAAAAACATA
ACTCAGTCAAATGATATGTTAATATGAACTGGAATGCAAAGTGCATACTTTTTCATTCAAAATGGGTATTCTTGATTTCCTCAGAACTGA
TAAAAAATAATGCAACATCACCAACAGATCCTGTTATTTCCTCTGCAGGATACAGTTCAATATGATGCATGAAAAATGCTCCACATTTAA
AGGACATACCCGTGTATGTTATGAAAACATGGTTTGATACTTTGTTTATACTACCCTCAGCTGAACCCCTATATATGAATTCCGTTTTCA
TTGTCAAGAATGTTACTGTAGTATTCTCTAGAACTTCAATGTCTTTGTGGACATTGTTGTGAAATTGGTGACTATGTATAGCTGTCGTTA
GTCTTTTTGGGAGACTGTTAGGAACAGTTTGTACAGTATATACTTGCTAAATGAGTTCATTATGACAGTCACATTGCTGATGCTTACTGA
GAACTATTACCTACTCTTGGCTCCTGTTACTCCGTAGGCTTCTTAATCTTCCAGGCATTACAGCAGCACAGTGTTCTACTTTTTACATCA
TTTCTATGTTCGGTTGTTTTTAGGCATAAACAATGTGTATTGCAGTGCATTTCGGCATTTGTGCCATACTGAAAGAATCAAAAACAAATC
ATCCAAATTAAATTTCAAACATTATTTCAGAGAACACAGGGCAAGACACATACAGTGCCTTCAGATATTAAGCATTCCACAACATCGTGC
ATTCTGTATCAGCTGGTCCAGTCCATTCTGGGTCCTAGATTACTGTCATTGTCTAAAAGTAACTTTTAAAAAGCAGAGTTCATGAAAACT
GCAATGCTGGGAAAAGAAGGAAACATGAAAATAAAAATAAGACAGTTTATTAGAAATAGCATTTCCTCATAAGCATAAAAAGAAAATCTT
TGTTGCCAACTGAAGCACATGATGATTTTGTGGTCCTTTATGGTTTCTATTACATTCAGTAAGAAAGATGTCAACATGCTAGAAAATTAA
TTTTAAAACTAAGTTATTCCAACACTAAAAGCATACAACAGCATGCCAACAGTAATATATTATTCTCCAAGACTTTACCTATGTAAGTGT
TCAAAACTCTGCAGCATTAAACAACGTGTATGCAAATTGTTATGGATACATTTCAGAATCTAAGAAATCAGGCAAGTGCTTAAAAGGCCA
ACGGTCCAAGGGATTACATCTGCAGTTTAAAAAGTAAATATATATTCTATCGTATTCATAAACAATATCTATCAAATGGGTTACCTCCAA
ATATGAAAATCTATAACAACCTATGGTTGAAGGAATGCTCAGTTTCATTTGCCAATAAATTGGTTTCTCATAACTTGCATCAAGTTTAAT
TTTAAGTAAAGCTTTTTATATGTAGATATTTTGTTGAATTTGTAAATACACTTAAAATGTAGATGCTATATGCTTATAGGTGTTACATAC
AAATAAACATGCAATGTTTATGTTGTACTGTATAAGAGGTAAGCTAATTAATGCAGTGAATGGGATTGGAAAGCATCTACTTAAATATCT
ATTGGGTTCCCCCCTCCCCCCACCTTTTTTGCTGTGAAACTGAAATAGTGAACTTTTCTACGTATTGACAGCAGATTTTTCGATGAAATC
TTCAGAGCTTTGCCTATGGGGCACAGTAGGCCTAGTAACCTGGCATGTTTGATATATGTAGGTAAAGCATAATTTAAAGTAATCCCAGGT
AAAGATGGCCCTAAATACTTTCATGTCTCTATATTCATTTTTCACAGATCCACCTGTCTCTTGAAAATATAAAAAGACAAAACAGGTTTG
CCTTGGCATCAGAGAGCACAAAGATTAAAAGTTACTTTAAATTTGCCAATATTTTGGGAGAACAATAAAACTACATTTTTTCCTCTTCCA
TACTGGTAGATGCGAAATTTATCTGTGCATGAAAGGGTCACTTCTGTAATAGTGCAACAGATTTGGTATTAAAAATTAAATGTGGTTTTA
AAAGTTCCTCTCTCTTTTGTAATTTATGTTCCCAATTGAGTGTGAATGTCCAAGTAATGGTGTATGTAATGGTACAGGCAAATGTGACTG

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000413765_chr7_107800937_-_3655nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGA
AAAAAGGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCC
AGTTCAATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTT
CTCCTGTCAACGCCATGAATTCCTTTGTTTAATTTTTAAGCTCTTTGCCAATATTCCATTTCTCTAGAATGTTTATCCTAAGCACTTGTT
TGTCAGCCCTCTCATACTATGAACATATGGGTAGAGAGTATATTTTCTGCTGTATGTTAGTATTATGAGAATAGTTACAGCAAAAACATA
ACTCAGTCAAATGATATGTTAATATGAACTGGAATGCAAAGTGCATACTTTTTCATTCAAAATGGGTATTCTTGATTTCCTCAGAACTGA
TAAAAAATAATGCAACATCACCAACAGATCCTGTTATTTCCTCTGCAGGATACAGTTCAATATGATGCATGAAAAATGCTCCACATTTAA
AGGACATACCCGTGTATGTTATGAAAACATGGTTTGATACTTTGTTTATACTACCCTCAGCTGAACCCCTATATATGAATTCCGTTTTCA
TTGTCAAGAATGTTACTGTAGTATTCTCTAGAACTTCAATGTCTTTGTGGACATTGTTGTGAAATTGGTGACTATGTATAGCTGTCGTTA
GTCTTTTTGGGAGACTGTTAGGAACAGTTTGTACAGTATATACTTGCTAAATGAGTTCATTATGACAGTCACATTGCTGATGCTTACTGA
GAACTATTACCTACTCTTGGCTCCTGTTACTCCGTAGGCTTCTTAATCTTCCAGGCATTACAGCAGCACAGTGTTCTACTTTTTACATCA
TTTCTATGTTCGGTTGTTTTTAGGCATAAACAATGTGTATTGCAGTGCATTTCGGCATTTGTGCCATACTGAAAGAATCAAAAACAAATC
ATCCAAATTAAATTTCAAACATTATTTCAGAGAACACAGGGCAAGACACATACAGTGCCTTCAGATATTAAGCATTCCACAACATCGTGC
ATTCTGTATCAGCTGGTCCAGTCCATTCTGGGTCCTAGATTACTGTCATTGTCTAAAAGTAACTTTTAAAAAGCAGAGTTCATGAAAACT
GCAATGCTGGGAAAAGAAGGAAACATGAAAATAAAAATAAGACAGTTTATTAGAAATAGCATTTCCTCATAAGCATAAAAAGAAAATCTT
TGTTGCCAACTGAAGCACATGATGATTTTGTGGTCCTTTATGGTTTCTATTACATTCAGTAAGAAAGATGTCAACATGCTAGAAAATTAA
TTTTAAAACTAAGTTATTCCAACACTAAAAGCATACAACAGCATGCCAACAGTAATATATTATTCTCCAAGACTTTACCTATGTAAGTGT
TCAAAACTCTGCAGCATTAAACAACGTGTATGCAAATTGTTATGGATACATTTCAGAATCTAAGAAATCAGGCAAGTGCTTAAAAGGCCA
ACGGTCCAAGGGATTACATCTGCAGTTTAAAAAGTAAATATATATTCTATCGTATTCATAAACAATATCTATCAAATGGGTTACCTCCAA
ATATGAAAATCTATAACAACCTATGGTTGAAGGAATGCTCAGTTTCATTTGCCAATAAATTGGTTTCTCATAACTTGCATCAAGTTTAAT
TTTAAGTAAAGCTTTTTATATGTAGATATTTTGTTGAATTTGTAAATACACTTAAAATGTAGATGCTATATGCTTATAGGTGTTACATAC
AAATAAACATGCAATGTTTATGTTGTACTGTATAAGAGGTAAGCTAATTAATGCAGTGAATGGGATTGGAAAGCATCTACTTAAATATCT
ATTGGGTTCCCCCCTCCCCCCACCTTTTTTGCTGTGAAACTGAAATAGTGAACTTTTCTACGTATTGACAGCAGATTTTTCGATGAAATC
TTCAGAGCTTTGCCTATGGGGCACAGTAGGCCTAGTAACCTGGCATGTTTGATATATGTAGGTAAAGCATAATTTAAAGTAATCCCAGGT
AAAGATGGCCCTAAATACTTTCATGTCTCTATATTCATTTTTCACAGATCCACCTGTCTCTTGAAAATATAAAAAGACAAAACAGGTTTG
CCTTGGCATCAGAGAGCACAAAGATTAAAAGTTACTTTAAATTTGCCAATATTTTGGGAGAACAATAAAACTACATTTTTTCCTCTTCCA
TACTGGTAGATGCGAAATTTATCTGTGCATGAAAGGGTCACTTCTGTAATAGTGCAACAGATTTGGTATTAAAAATTAAATGTGGTTTTA
AAAGTTCCTCTCTCTTTTGTAATTTATGTTCCCAATTGAGTGTGAATGTCCAAGTAATGGTGTATGTAATGGTACAGGCAAATGTGACTG

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000351718_chr7_107800937_-_3630nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGA
AAAAAGGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCC
AGTTCAATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTT
CTCCTGTCAACGCCATGAATTCCTTTGTTTAATTTTTAAGCTCTTTGCCAATATTCCATTTCTCTAGAATGTTTATCCTAAGCACTTGTT
TGTCAGCCCTCTCATACTATGAACATATGGGTAGAGAGTATATTTTCTGCTGTATGTTAGTATTATGAGAATAGTTACAGCAAAAACATA
ACTCAGTCAAATGATATGTTAATATGAACTGGAATGCAAAGTGCATACTTTTTCATTCAAAATGGGTATTCTTGATTTCCTCAGAACTGA
TAAAAAATAATGCAACATCACCAACAGATCCTGTTATTTCCTCTGCAGGATACAGTTCAATATGATGCATGAAAAATGCTCCACATTTAA
AGGACATACCCGTGTATGTTATGAAAACATGGTTTGATACTTTGTTTATACTACCCTCAGCTGAACCCCTATATATGAATTCCGTTTTCA
TTGTCAAGAATGTTACTGTAGTATTCTCTAGAACTTCAATGTCTTTGTGGACATTGTTGTGAAATTGGTGACTATGTATAGCTGTCGTTA
GTCTTTTTGGGAGACTGTTAGGAACAGTTTGTACAGTATATACTTGCTAAATGAGTTCATTATGACAGTCACATTGCTGATGCTTACTGA
GAACTATTACCTACTCTTGGCTCCTGTTACTCCGTAGGCTTCTTAATCTTCCAGGCATTACAGCAGCACAGTGTTCTACTTTTTACATCA
TTTCTATGTTCGGTTGTTTTTAGGCATAAACAATGTGTATTGCAGTGCATTTCGGCATTTGTGCCATACTGAAAGAATCAAAAACAAATC
ATCCAAATTAAATTTCAAACATTATTTCAGAGAACACAGGGCAAGACACATACAGTGCCTTCAGATATTAAGCATTCCACAACATCGTGC
ATTCTGTATCAGCTGGTCCAGTCCATTCTGGGTCCTAGATTACTGTCATTGTCTAAAAGTAACTTTTAAAAAGCAGAGTTCATGAAAACT
GCAATGCTGGGAAAAGAAGGAAACATGAAAATAAAAATAAGACAGTTTATTAGAAATAGCATTTCCTCATAAGCATAAAAAGAAAATCTT
TGTTGCCAACTGAAGCACATGATGATTTTGTGGTCCTTTATGGTTTCTATTACATTCAGTAAGAAAGATGTCAACATGCTAGAAAATTAA
TTTTAAAACTAAGTTATTCCAACACTAAAAGCATACAACAGCATGCCAACAGTAATATATTATTCTCCAAGACTTTACCTATGTAAGTGT
TCAAAACTCTGCAGCATTAAACAACGTGTATGCAAATTGTTATGGATACATTTCAGAATCTAAGAAATCAGGCAAGTGCTTAAAAGGCCA
ACGGTCCAAGGGATTACATCTGCAGTTTAAAAAGTAAATATATATTCTATCGTATTCATAAACAATATCTATCAAATGGGTTACCTCCAA
ATATGAAAATCTATAACAACCTATGGTTGAAGGAATGCTCAGTTTCATTTGCCAATAAATTGGTTTCTCATAACTTGCATCAAGTTTAAT
TTTAAGTAAAGCTTTTTATATGTAGATATTTTGTTGAATTTGTAAATACACTTAAAATGTAGATGCTATATGCTTATAGGTGTTACATAC
AAATAAACATGCAATGTTTATGTTGTACTGTATAAGAGGTAAGCTAATTAATGCAGTGAATGGGATTGGAAAGCATCTACTTAAATATCT
ATTGGGTTCCCCCCTCCCCCCACCTTTTTTGCTGTGAAACTGAAATAGTGAACTTTTCTACGTATTGACAGCAGATTTTTCGATGAAATC
TTCAGAGCTTTGCCTATGGGGCACAGTAGGCCTAGTAACCTGGCATGTTTGATATATGTAGGTAAAGCATAATTTAAAGTAATCCCAGGT
AAAGATGGCCCTAAATACTTTCATGTCTCTATATTCATTTTTCACAGATCCACCTGTCTCTTGAAAATATAAAAAGACAAAACAGGTTTG
CCTTGGCATCAGAGAGCACAAAGATTAAAAGTTACTTTAAATTTGCCAATATTTTGGGAGAACAATAAAACTACATTTTTTCCTCTTCCA
TACTGGTAGATGCGAAATTTATCTGTGCATGAAAGGGTCACTTCTGTAATAGTGCAACAGATTTGGTATTAAAAATTAAATGTGGTTTTA
AAAGTTCCTCTCTCTTTTGTAATTTATGTTCCCAATTGAGTGTGAATGTCCAAGTAATGGTGTATGTAATGGTACAGGCAAATGTGACTG

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379024_chr7_107800937_-_3175nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGA
AAAAAGGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCC
AGTTCAATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTT
CTCCTGTCAACGCCATGAATTCCTTTGTTTAATTTTTAAGCTCTTTGCCAATATTCCATTTCTCTAGAATGTTTATCCTAAGCACTTGTT
TGTCAGCCCTCTCATACTATGAACATATGGGTAGAGAGTATATTTTCTGCTGTATGTTAGTATTATGAGAATAGTTACAGCAAAAACATA
ACTCAGTCAAATGATATGTTAATATGAACTGGAATGCAAAGTGCATACTTTTTCATTCAAAATGGGTATTCTTGATTTCCTCAGAACTGA
TAAAAAATAATGCAACATCACCAACAGATCCTGTTATTTCCTCTGCAGGATACAGTTCAATATGATGCATGAAAAATGCTCCACATTTAA
AGGACATACCCGTGTATGTTATGAAAACATGGTTTGATACTTTGTTTATACTACCCTCAGCTGAACCCCTATATATGAATTCCGTTTTCA
TTGTCAAGAATGTTACTGTAGTATTCTCTAGAACTTCAATGTCTTTGTGGACATTGTTGTGAAATTGGTGACTATGTATAGCTGTCGTTA
GTCTTTTTGGGAGACTGTTAGGAACAGTTTGTACAGTATATACTTGCTAAATGAGTTCATTATGACAGTCACATTGCTGATGCTTACTGA
GAACTATTACCTACTCTTGGCTCCTGTTACTCCGTAGGCTTCTTAATCTTCCAGGCATTACAGCAGCACAGTGTTCTACTTTTTACATCA
TTTCTATGTTCGGTTGTTTTTAGGCATAAACAATGTGTATTGCAGTGCATTTCGGCATTTGTGCCATACTGAAAGAATCAAAAACAAATC
ATCCAAATTAAATTTCAAACATTATTTCAGAGAACACAGGGCAAGACACATACAGTGCCTTCAGATATTAAGCATTCCACAACATCGTGC
ATTCTGTATCAGCTGGTCCAGTCCATTCTGGGTCCTAGATTACTGTCATTGTCTAAAAGTAACTTTTAAAAAGCAGAGTTCATGAAAACT
GCAATGCTGGGAAAAGAAGGAAACATGAAAATAAAAATAAGACAGTTTATTAGAAATAGCATTTCCTCATAAGCATAAAAAGAAAATCTT
TGTTGCCAACTGAAGCACATGATGATTTTGTGGTCCTTTATGGTTTCTATTACATTCAGTAAGAAAGATGTCAACATGCTAGAAAATTAA
TTTTAAAACTAAGTTATTCCAACACTAAAAGCATACAACAGCATGCCAACAGTAATATATTATTCTCCAAGACTTTACCTATGTAAGTGT
TCAAAACTCTGCAGCATTAAACAACGTGTATGCAAATTGTTATGGATACATTTCAGAATCTAAGAAATCAGGCAAGTGCTTAAAAGGCCA
ACGGTCCAAGGGATTACATCTGCAGTTTAAAAAGTAAATATATATTCTATCGTATTCATAAACAATATCTATCAAATGGGTTACCTCCAA
ATATGAAAATCTATAACAACCTATGGTTGAAGGAATGCTCAGTTTCATTTGCCAATAAATTGGTTTCTCATAACTTGCATCAAGTTTAAT
TTTAAGTAAAGCTTTTTATATGTAGATATTTTGTTGAATTTGTAAATACACTTAAAATGTAGATGCTATATGCTTATAGGTGTTACATAC
AAATAAACATGCAATGTTTATGTTGTACTGTATAAGAGGTAAGCTAATTAATGCAGTGAATGGGATTGGAAAGCATCTACTTAAATATCT
ATTGGGTTCCCCCCTCCCCCCACCTTTTTTGCTGTGAAACTGAAATAGTGAACTTTTCTACGTATTGACAGCAGATTTTTCGATGAAATC

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000379022_chr7_107800937_-_1178nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGGCTGTTTTCATTTGTTTCTTCTGCAT

>In-frame_LAMB1_ENST00000393561_chr7_107626467_-_NRCAM_ENST00000425651_chr7_107800937_-_1382nt
GGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTC
TTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCT
TCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAA
CTCTGTTGCCTGTCCTTCCCGCAGCCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCT
GCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACT
GTATCGTCAGCCACTTGCAGGAGGACAAAAAATGCTTCATATGCAATTCCCAAGATCCTTATCATGAGACCCTGAATCCTGACAGCCATC
TCATTGAAAATGTGGTCACTACATTTGCTCCAAACCGCCTTAAGATTTGGTGGCAATCTGAAAATGGTGTGGAAAATGTAACTATCCAAC
TGGATTTGGAAGCAGAATTCCATTTTACTCATCTCATAATGACTTTCAAGACATTCCGTCCAGCTGCTATGCTGATAGAACGATCGTCCG
ACTTTGGGAAAACCTGGGGTGTGTATAGATACTTCGCCTATGACTGTGAGGCCTCGTTTCCAGGCATTTCAACTGGCCCCATGAAAAAAG
TCGATGACATAATTTGTGATTCTCGATATTCTGACATTGAACCCTCAACTGAAGGAGAGGTGATATTTCGTGCTTTAGATCCTGCTTTCA
AAATAGAAGATCCTTATAGCCCAAGGATACAGACGATGGCAAGCCGGCAGGTGGATATTGCAACTCAGGGCTGGTTCATTGGTCTGATGT
GTGCTGTTGCTCTCCTTATCTTAATTTTGCTGATTGTTTGCTTCATCAGAAGAAACAAGGGTGGTAAATATCCAGTTAAAGAAAAGGAAG
ATGCCCATGCTGACCCTGAAATCCAGCCTATGAAGGAAGATGATGGGACATTTGGAGAATACAGTGATGCAGAAGACCACAAGCCTTTGA
AAAAAGGAAGTCGAACTCCTTCAGACAGGACTGTGAAAAAAGAAGATAGTGACGACAGCCTAGTTGACTATGGAGAAGGGGTTAATGGCC
AGTTCAATGAGGATGGCTCCTTTATTGGACAATACAGTGGTAAGAAAGAGAAAGAGCCGGCTGAAGGAAACGAAAGCTCAGAGGCACCTT


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FusionGenePPI for LAMB1_NRCAM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
LAMB1TGFB1, ATXN7, CACNA1A, LAMC1, UBC, ATXN7L2, GFI1B, FBXO6, NQO1, DPY30, HSPD1, PDIA3, ERBB2IP, HECW2, KIAA1033, POLR2E, ANTXR2, PA2G4, LGALS3, NTF3, OGN, LGALS9, TMEM25, PTPRK, CD96, PSMD5, NTRK1, PSMC5, KIF11, FGFR1OP, SERPINA12, OS9, DEFA1, COLEC12, CRP, LYZL2, PSG8, BCAM, LMNANRCAMPTPRB, CNTN2, HSPA12A, MACF1, MAGI3, LNX1, FRMD5, NTRK1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LAMB1_NRCAM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LAMB1_NRCAM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLAMB1C0004352Autistic Disorder1CTD_human
HgeneLAMB1C0009324Ulcerative Colitis1CTD_human
HgeneLAMB1C0009363Congenital ocular coloboma (disorder)1CTD_human
HgeneLAMB1C0014175Endometriosis1CTD_human
TgeneNRCAMC0004352Autistic Disorder2CTD_human
TgeneNRCAMC0009404Colorectal Neoplasms2CTD_human
TgeneNRCAMC0236969Substance-Related Disorders1CTD_human
TgeneNRCAMC1458155Mammary Neoplasms1CTD_human